Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
HumanPhenoMalignant neoplasm of the central nervous system

PMS2 NF1 ELP1 FGFR1 SKI ALK CASZ1

1.52e-0699317HP:0100836
HumanPhenoAbnormal hair pattern

SHROOM4 NF1 MAN2B1 NECTIN1 ESAM ASXL2 FGFR1 TAF1 HERC2 SKI PQBP1 ALK CASZ1 EDNRB

1.38e-056763114HP:0010720
HumanPhenoNeuroepithelial neoplasm

PMS2 NF1 FGFR1 SKI ALK CASZ1

1.51e-0592316HP:0030063
HumanPhenoNeuroectodermal neoplasm

PMS2 NF1 FGFR1 SKI ALK CASZ1

1.71e-0594316HP:0030061
HumanPhenoNervous tissue neoplasm

PMS2 NF1 FGFR1 SKI ALK CASZ1

1.71e-0594316HP:0030060
HumanPhenoHypertrichosis

SHROOM4 MAN2B1 NECTIN1 ESAM ASXL2 FGFR1 TAF1 SKI ALK CASZ1 EDNRB

2.18e-054253111HP:0000998
HumanPhenoNeuroblastoma

PMS2 NF1 SKI ALK CASZ1

2.79e-0561315HP:0003006
HumanPhenoNeuroblastic tumor

PMS2 NF1 SKI ALK CASZ1

2.79e-0561315HP:0004376
HumanPhenoPeripheral primitive neuroectodermal neoplasm

PMS2 NF1 SKI ALK CASZ1

3.02e-0562315HP:0030067
HumanPhenoAbnormality of the sphenoid sinus

NF1 MAN2B1

3.58e-052312HP:0430022
HumanPhenoPrimitive neuroectodermal tumor

PMS2 NF1 SKI ALK CASZ1

4.41e-0567315HP:0030065
HumanPhenoNeoplasm of the central nervous system

PMS2 NF1 ELP1 FGFR1 SKI ALK CASZ1

7.30e-05178317HP:0100006
HumanPhenoTalipes

SHROOM4 MAN2B1 NECTIN1 ESAM FGFR1 TAF1 FXN HERC2 SKI CASZ1 DYNC1H1 MYBPC1

8.14e-055833112HP:0001883
HumanPhenoPositional foot deformity

SHROOM4 MAN2B1 NECTIN1 ESAM FGFR1 TAF1 FXN HERC2 SKI CASZ1 DYNC1H1 MYBPC1

8.71e-055873112HP:0005656
HumanPhenoNeoplasm of the nervous system

PMS2 NF1 ELP1 FGFR1 SKI ALK CASZ1

1.30e-04195317HP:0004375
HumanPhenoAbnormal hair quantity

SHROOM4 NF1 MAN2B1 NECTIN1 ESAM ASXL2 FGFR1 TAF1 SKI PQBP1 ALK CASZ1 MSTO1 EDNRB

3.03e-048883114HP:0011362
HumanPhenoImpairment in personality functioning

SHROOM4 NLGN3 PMS2 NF1 MAN2B1 PER2 NECTIN1 ELP1 FGFR1 TAF1 FXN HERC2 SKI PQBP1 CASZ1 MSTO1

3.41e-0411413116HP:0031466
DomainIg_I-set

CHL1 UNC5A HMCN1 KALRN ESAM FGFR1 MYBPC1

2.02e-05190827IPR013098
DomainI-set

CHL1 UNC5A HMCN1 KALRN ESAM FGFR1 MYBPC1

2.02e-05190827PF07679
DomainIGc2

CHL1 HMCN1 KALRN NECTIN1 ESAM FGFR1 MYBPC1

7.79e-05235827SM00408
DomainIg_sub2

CHL1 HMCN1 KALRN NECTIN1 ESAM FGFR1 MYBPC1

7.79e-05235827IPR003598
DomainIMD

BAIAP2 MTSS2

1.89e-045822PS51338
DomainIMD

BAIAP2 MTSS2

2.82e-046822PF08397
DomainIG

CHL1 UNC5A HMCN1 KALRN NECTIN1 ESAM FGFR1 MYBPC1

5.18e-04421828SM00409
DomainIg_sub

CHL1 UNC5A HMCN1 KALRN NECTIN1 ESAM FGFR1 MYBPC1

5.18e-04421828IPR003599
DomainTyrKc

CSK INSRR FGFR1 ALK

6.08e-0488824SM00219
DomainTyr_kinase_cat_dom

CSK INSRR FGFR1 ALK

6.08e-0488824IPR020635
Domain-

CHL1 UNC5A PTPRB HMCN1 KALRN NECTIN1 INSRR ESAM FGFR1 MYBPC1

6.35e-0466382102.60.40.10
Domainfn3

CHL1 PTPRB KALRN INSRR MYBPC1

7.35e-04162825PF00041
DomainPROTEIN_KINASE_TYR

CSK INSRR FGFR1 ALK

8.77e-0497824PS00109
DomainTyr_kinase_AS

CSK INSRR FGFR1 ALK

8.77e-0497824IPR008266
DomainTyr_kinase_rcpt_2_CS

INSRR ALK

1.02e-0311822IPR002011
DomainIg-like_fold

CHL1 UNC5A PTPRB HMCN1 KALRN NECTIN1 INSRR ESAM FGFR1 MYBPC1

1.03e-037068210IPR013783
DomainRECEPTOR_TYR_KIN_II

INSRR ALK

1.22e-0312822PS00239
DomainDUF4599

SPATA31C2 SPATA31C1

1.22e-0312822PF15371
DomainDUF4599

SPATA31C2 SPATA31C1

1.22e-0312822IPR027970
DomainFN3

CHL1 PTPRB KALRN INSRR MYBPC1

1.33e-03185825SM00060
DomainIG_LIKE

CHL1 UNC5A HMCN1 KALRN NECTIN1 ESAM FGFR1 MYBPC1

1.40e-03491828PS50835
DomainI-BAR_dom

BAIAP2 MTSS2

1.44e-0313822IPR013606
DomainIg-like_dom

CHL1 UNC5A HMCN1 KALRN NECTIN1 ESAM FGFR1 MYBPC1

1.63e-03503828IPR007110
DomainFN3

CHL1 PTPRB KALRN INSRR MYBPC1

1.83e-03199825PS50853
DomainMAM_1

ZAN ALK

2.20e-0316822PS00740
DomainFN3_dom

CHL1 PTPRB KALRN INSRR MYBPC1

2.27e-03209825IPR003961
DomainPkinase_Tyr

CSK INSRR FGFR1 ALK

2.51e-03129824PF07714
DomainMAM

ZAN ALK

2.78e-0318822PF00629
DomainMAM_dom

ZAN ALK

2.78e-0318822IPR000998
DomainMAM_2

ZAN ALK

2.78e-0318822PS50060
DomainSer-Thr/Tyr_kinase_cat_dom

CSK INSRR FGFR1 ALK

3.20e-03138824IPR001245
DomainRRM_dom_euk

TIAL1 RBM19

4.54e-0323822IPR003954
DomainRRM_1

TIAL1 RBM19

4.54e-0323822SM00361
Pubmed

Functional proteomics mapping of a human signaling pathway.

MYG1 SF3B1 MAN2B1 DCP1B EXPH5 RBM19 ASXL2 HERC2 SKI MGA ANKLE2 DYNC1H1

4.83e-08591911215231748
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

CRYBG2 FASN MAN2B1 PER2 KALRN BTBD7 RBM19 NADK FGFR1 HERC2 POM121C CASZ1 DYNC1H1 IQCE

1.08e-061105911435748872
Pubmed

A human MAP kinase interactome.

SF3B1 POM121 JADE2 EXPH5 TAF1 BAIAP2 HERC2 POM121C MGA

5.37e-0648691920936779
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SHROOM4 SEC16B NLGN3 POM121 EXPH5 UBR3 POM121C MGA CASZ1

6.02e-0649391915368895
Pubmed

Neurofibromin interacts with the cytoplasmic Dynein Heavy Chain 1 in melanosomes of human melanocytes.

NF1 DYNC1H1

6.77e-06291223583712
Pubmed

Molecular characterization reveals NF1 deletions and FGFR1-activating mutations in a pediatric spinal oligodendroglioma.

NF1 FGFR1

6.77e-06291227862886
Pubmed

NF1 mutation drives neuronal activity-dependent initiation of optic glioma.

NLGN3 NF1

6.77e-06291234040258
Pubmed

Genetic inhibition of Anaplastic Lymphoma Kinase rescues cognitive impairments in Neurofibromatosis 1 mutant mice.

NF1 ALK

6.77e-06291228057529
Pubmed

Pharmacological inhibition of Anaplastic Lymphoma Kinase rescues spatial memory impairments in Neurofibromatosis 1 mutant mice.

NF1 ALK

6.77e-06291228629962
Pubmed

Genetic interactions between neurofibromin and endothelin receptor B in mice.

NF1 EDNRB

6.77e-06291223555837
Pubmed

The double face of the histone variant H3.3.

H3Y2 H3Y1

6.77e-06291221263457
Pubmed

Identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y.

H3Y2 H3Y1

6.77e-06291220819935
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

CCNT1 INTS13 TAF1 SKI MGA LIN9 CASZ1

6.95e-0626891733640491
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NLGN3 NF1 SF3B1 KALRN PRRC2C TRIOBP DAPK1 BAIAP2 HERC2 MGA DYNC1H1 MTSS2

8.04e-06963911228671696
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

NLGN3 NF1 KALRN AGAP11 BAIAP2 PQBP1 DYNC1H1

9.46e-0628191728706196
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

SEC16B FASN SF3B1 TIAL1 PRRC2C RBM19 ELP1 DHX57 BAIAP2 HERC2 PQBP1 ALK DYNC1H1 NCBP3

1.28e-051371911436244648
Pubmed

Hirschsprung Disease Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

NF1 ELP1 EDNRB

1.37e-051891320301612
Pubmed

Rosette-forming glioneuronal tumors share a distinct DNA methylation profile and mutations in FGFR1, with recurrent co-mutation of PIK3CA and NF1.

NF1 FGFR1

2.03e-05391231250151
Pubmed

POM121 inhibits the macrophage inflammatory response by impacting NF-κB P65 nuclear accumulation.

POM121 POM121C

2.03e-05391230802453
Pubmed

FGFR1 signaling in hypertrophic chondrocytes is attenuated by the Ras-GAP neurofibromin during endochondral bone formation.

NF1 FGFR1

2.03e-05391225616962
Pubmed

Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.

POM121 POM121C

2.03e-05391235507432
Pubmed

Activating mutations in the MAP-kinase pathway define non-ossifying fibroma of bone.

NF1 FGFR1

2.03e-05391230549028
Pubmed

IRSp53: crossing the road of membrane and actin dynamics in the formation of membrane protrusions.

BAIAP2 MTSS2

2.03e-05391218215522
Pubmed

DUX4-Induced Histone Variants H3.X and H3.Y Mark DUX4 Target Genes for Expression.

H3Y2 H3Y1

2.03e-05391231722199
Pubmed

Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma.

NF1 SF3B1

2.03e-05391228296713
Pubmed

Lack of Association between Genetic Polymorphism of Circadian Genes (PER2, PER3, CLOCK and OX2R) with Late Onset Depression and Alzheimer's Disease in a Sample of a Brazilian Population (Circadian Genes, Late-Onset Depression and Alzheimer's Disease).

PER2 HCRTR2

4.05e-05491227335043
Pubmed

Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes.

POM121 POM121C

4.05e-05491217900573
Pubmed

A novel actin bundling/filopodium-forming domain conserved in insulin receptor tyrosine kinase substrate p53 and missing in metastasis protein.

BAIAP2 MTSS2

4.05e-05491214752106
Pubmed

The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase.

UNC5A DAPK1

4.05e-05491215729359
Pubmed

Relationship between APOE, PER2, PER3 and OX2R Genetic Variants and Neuropsychiatric Symptoms in Patients with Alzheimer's Disease.

PER2 HCRTR2

4.05e-05491236901420
Pubmed

Differential effects of neurofibromin gene dosage on melanocyte development.

NF1 EDNRB

4.05e-05491222810304
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

PRRC2C HERC2 MGA DYNC1H1

4.87e-057691427542412
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

CRYBG2 SGSM1 JADE2 NADK TRIOBP ASXL2 HERC2

5.57e-0537191715747579
Pubmed

The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing.

POM121 PRRC2C POM121C

6.03e-052991317577209
Pubmed

Nectin-1 binds and signals through the fibroblast growth factor receptor.

NECTIN1 FGFR1

6.74e-05591222955284
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

CDCA3 POM121 EXPH5 USP54 POM121C ANKLE2

6.88e-0526391634702444
Pubmed

The protein tyrosine kinase family of the human genome.

CSK INSRR FGFR1 ALK

6.88e-058391411114734
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

CHL1 HMCN1 KALRN NECTIN1 ESAM

6.94e-0516291525826454
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

FASN NF1 SF3B1 POM121 TIAL1 ELP1 HERC2 PQBP1 MGA DYNC1H1 NCBP3

7.54e-051024911124711643
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

CCNT1 INTS13 DHX57 TAF1 BAIAP2 HERC2 MGA DYNC1H1

8.06e-0553391830554943
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CDCA3 PMS2 PTPRB CSK TRIOBP ELP1 UBR3 BAIAP2 HERC2 PQBP1 ANKLE2

9.34e-051049911127880917
Pubmed

Fine-scale comparative mapping of the human 7q11.23 region and the orthologous region on mouse chromosome 5G: the low-copy repeats that flank the Williams-Beuren syndrome deletion arose at breakpoint sites of an evolutionary inversion(s).

POM121 ZAN POM121C

1.07e-043591311013070
Pubmed

Genetic variants in COL2A1, COL11A2, and IRF6 contribute risk to nonsyndromic cleft palate.

NECTIN1 FGFR1 SKI

1.16e-043691320672350
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PMS2 LARP6 SF3B1 KALRN JADE2 TRIOBP TAF1 USP54 BAIAP2 HERC2 DYNC1H1 MSTO1

1.31e-041285911235914814
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

SF3B1 CSK EXPH5 INTS13 TRIOBP ELP1 ANKLE2 DYNC1H1

1.33e-0457391828330616
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

NLGN3 NF1 ELP1 AGAP11 BAIAP2 HERC2 MTSS2

1.39e-0443091732581705
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

PTPRB INSRR FGFR1 ALK

1.47e-0410191423382219
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

ARHGAP22 SF3B1 CSK INTS13 TAF1 SKI MGA LIN9

1.49e-0458391829844126
Pubmed

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

POM121 EXPH5 RBM19 ANKLE2

1.53e-041029149734811
Pubmed

Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.

INSRR FGFR1 ALK

1.60e-044091330898150
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

NF1 SF3B1 KALRN AKR7L PRRC2C NECTIN1 TRIOBP UBR3 BAIAP2 MTX1 ANKLE2

1.91e-041139911136417873
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

FASN SF3B1 PRRC2C USP54 CCDC157

1.95e-0420291524639526
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

CCNT1 SF3B1 TIAL1 PRRC2C RBM19 TAF1 PQBP1 MGA ALK NCBP3

1.99e-04954911036373674
Pubmed

TFIID component TAF7 functionally interacts with both TFIIH and P-TEFb.

CCNT1 TAF1

2.41e-04991218391197
Pubmed

Large-scale structural analysis of the classical human protein tyrosine phosphatome.

PTPRB CSK ALK

2.58e-044791319167335
Pubmed

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.

FASN SF3B1 ELP1 MGA DYNC1H1

2.95e-0422191529991511
Pubmed

Dynein and kinesin regulate stress-granule and P-body dynamics.

TIAL1 DYNC1H1

3.01e-041091219825938
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

FASN NF1 SF3B1 PRRC2C ELP1 DHX57 HERC2 DYNC1H1

3.20e-0465391822586326
Pubmed

Interaction network of human early embryonic transcription factors.

ASXL2 TAF1 SKI POM121C MGA LIN9

3.28e-0435191638297188
Pubmed

Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins.

UNC5A SGSM1 AGAP11

3.29e-045191311853319
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

NLGN3 FASN NF1 SF3B1 KALRN PRRC2C ELP1 DAPK1 DHX57 USP54 BAIAP2 DYNC1H1

3.52e-041431911237142655
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

SF3B1 TIAL1 FGFR1 TAF1 CASZ1 DYNC1H1

3.64e-0435891632460013
Pubmed

Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin.

KALRN TAF1

3.67e-041191217607528
Pubmed

A comprehensive view of the epigenetic landscape part I: DNA methylation, passive and active DNA demethylation pathways and histone variants.

H3Y2 H3Y1

3.67e-041191225362550
Pubmed

Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis.

DAPK1 FGFR1

3.67e-041191212031912
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

SF3B1 PER2 RBM19 USP54 DYNC1H1

3.69e-0423291525515538
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

SEC16B NF1 SF3B1 PRRC2C RBM19 NADK

3.81e-0436191626167880
Pubmed

Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J.

OLFML1 HERC2 CASZ1

4.12e-045591329997285
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

FASN SF3B1 PRRC2C ASXL2 SKI MGA LIN9 CASZ1 DYNC1H1

4.15e-0485791925609649
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NF1 DCP1B EXPH5 PRRC2C NADK USP54 BAIAP2 RNF180 MTSS2

4.29e-0486191936931259
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

FASN TIAL1 RBM19 TAF1 DYNC1H1 NCBP3

4.34e-0437091622922362
Pubmed

An Eph-related receptor protein tyrosine kinase gene segmentally expressed in the developing mouse hindbrain.

CSK FGFR1

4.39e-04129121281307
Pubmed

Chromatin dynamics associated with HIV-1 Tat-activated transcription.

CCNT1 TAF1

4.39e-041291219716452
Pubmed

Loss of late primitive streak mesoderm and interruption of left-right morphogenesis in the Ednrb(s-1Acrg) mutant mouse.

FGFR1 EDNRB

4.39e-041291210964471
Pubmed

Innate neural stem cell heterogeneity determines the patterning of glioma formation in children.

CHL1 NF1

4.39e-041291222789544
Pubmed

Coordinated diurnal regulation of genes from the Dlk1-Dio3 imprinted domain: implications for regulation of clusters of non-paralogous genes.

PER2 DYNC1H1

4.39e-041291217901046
Pubmed

Blood pressure and hypertension are associated with 7 loci in the Japanese population.

CSK CASZ1

5.18e-041391220479155
Pubmed

Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.

BAIAP2 MTSS2

5.18e-041391221406566
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

SF3B1 PARP16 RBM19 DHX57 HERC2

5.18e-0425091533536335
Pubmed

Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.

FASN SF3B1 DHX57 DYNC1H1

5.70e-0414491435681168
Pubmed

Capillary cell-type specialization in the alveolus.

PTPRB EDNRB

6.04e-041491233057196
Pubmed

Redundant functions of I-BAR family members, IRSp53 and IRTKS, are essential for embryonic development.

BAIAP2 EDNRB

6.04e-041491228067313
Pubmed

The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.

HMCN1 PRRC2C TRIOBP SKI

6.16e-0414791428977470
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

SHROOM4 SF3B1 KALRN TAF1 HERC2 POM121C MSTO1

6.26e-0455291710737800
Pubmed

IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration.

ELP1 DYNC1H1

6.95e-041591218303054
Pubmed

Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.

HERC2 EDNRB

6.95e-041591223548203
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

POM121 POM121C

6.95e-041591214697343
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UNC5A PER2 BTBD7 PRRC2C ASXL2 DYNC1H1

7.14e-0440791612693553
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

FASN SF3B1 MGA LIN9 DYNC1H1

7.58e-0427291531010829
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

FASN POM121 TIMM21 ELP1 MTX1 POM121C ANKLE2 RTN2 DYNC1H1

8.15e-0494291931073040
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

FASN NF1 SF3B1 CSK INTS13 ELP1 DYNC1H1

8.54e-0458291720467437
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

FASN SF3B1 PER2 CSK TRIOBP ASXL2 HERC2 NRIP3 LIN9 DYNC1H1

8.84e-041155911020360068
Pubmed

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

SF3B1 INSRR KRT87P DYNC1H1 IQCE

9.20e-0428491529459677
Pubmed

MTHFR and MSX1 contribute to the risk of nonsyndromic cleft lip/palate.

NECTIN1 SKI

1.01e-031891220572854
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

NF1 POM121 ELP1 USP54 HERC2 POM121C

1.07e-0344091634244565
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

POM121 KALRN TAF1 USP54 BAIAP2 FXN PQBP1

1.10e-0360891716713569
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

CCNT1 TAF1 HERC2 MGA LIN9 CASZ1 NCBP3

1.10e-0360891736089195
Pubmed

Proteostasis is essential during cochlear development for neuron survival and hair cell polarity.

NF1 ELP1

1.12e-031991231321879
Pubmed

Feto-maternal cholesterol transport regulated by β-Klotho-FGF15 axis is essential for fetal growth.

FASN FGFR1

1.12e-031991237541847
Pubmed

Lost in transcription: molecular mechanisms that control HIV latency.

CCNT1 TAF1

1.12e-031991223518577
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

CHL1 UNC5A HMCN1 KALRN FGFR1 MYBPC1

8.24e-06161546593
GeneFamilyI-BAR domain containing

BAIAP2 MTSS2

8.71e-0555421287
GeneFamilyFibronectin type III domain containing

CHL1 PTPRB KALRN INSRR MYBPC1

1.14e-04160545555
GeneFamilyReceptor Tyrosine Kinases|CD molecules

INSRR FGFR1 ALK

2.30e-0440543321
CoexpressionAIZARANI_LIVER_C13_LSECS_2

SGSM1 PTPRB TRIOBP ESAM FGFR1 BAIAP2 TAMALIN EDNRB

5.55e-06283898M39117
CoexpressionFIRESTEIN_PROLIFERATION

NF1 KALRN ELP1 TAF1 TSKS ALK

2.22e-05166896M5354
ToppCelldistal-Endothelial-Capillary_Intermediate_1-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SHROOM4 PTPRB EXPH5 ESAM BAIAP2 TAMALIN EDNRB

1.82e-0720091743bc48413b100a06f8edd9acd812296788fcbf5b
ToppCelldistal-Endothelial-Capillary_Intermediate_1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SHROOM4 PTPRB EXPH5 ESAM BAIAP2 TAMALIN EDNRB

1.82e-072009174d6714d48738cdee7d535923f6dd2431e5304741
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

CHL1 SHROOM4 KALRN ESAM TAMALIN EDNRB

1.90e-06180916b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM4 PTPRB HMCN1 PRRC2C ESAM EDNRB

2.29e-061869160ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|343B / Donor, Lineage, Cell class and subclass (all cells)

CHL1 SHROOM4 KALRN ESAM TAMALIN EDNRB

2.44e-06188916fe7143c36e4a883745862d3c3147cf751b440e46
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|343B / Donor, Lineage, Cell class and subclass (all cells)

CHL1 SHROOM4 KALRN ESAM TAMALIN EDNRB

2.44e-06188916cbf32b675a7cd0c808d5c9c22dfa7fa79fbe2437
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CHL1 KALRN ESAM TAMALIN CASZ1 EDNRB

2.59e-061909160e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CHL1 SHROOM4 KALRN ESAM TAMALIN EDNRB

2.59e-061909160a351609a72fd638c84b2435782e312ee6a33aac
ToppCellASK454-Endothelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

LARP6 PTPRB ESAM TAMALIN CASZ1 EDNRB

3.10e-0619691614dd6956ef420b660be0baf52a66960e57d75d16
ToppCellASK454-Endothelial-Endothelium|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

LARP6 PTPRB ESAM TAMALIN CASZ1 EDNRB

3.10e-061969162b777a2026b56839112fd179f2db482c49f4594a
ToppCellmedial-2-Endothelial-Capillary_Aerocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHL1 SHROOM4 KALRN EXPH5 ESAM EDNRB

3.39e-06199916c5048b31649a0b7eddcd481b0458ed96508f5561
ToppCelldistal-Endothelial-Capillary_Aerocyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHL1 SHROOM4 KALRN EXPH5 ESAM EDNRB

3.39e-061999169021f4be004efd51bb3658e5bbff53589356b3df
ToppCellmedial-Endothelial-Capillary_Aerocyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHL1 SHROOM4 KALRN EXPH5 ESAM EDNRB

3.39e-0619991684e30c39c2f050aa64af167999824c1cba32ba05
ToppCellmedial-Endothelial-Capillary_Aerocyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHL1 SHROOM4 KALRN EXPH5 ESAM EDNRB

3.39e-06199916f1039d1ab498fc58f0feba545df05833c235db74
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SHROOM4 PTPRB ESAM TAMALIN DYNC1H1 EDNRB

3.48e-0620091672ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CHL1 SHROOM4 KALRN EXPH5 ESAM EDNRB

3.48e-062009163653002c805c314043e2a7b0c9980dfe952dc53e
ToppCellmedial-2-Endothelial-Capillary_Intermediate_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SHROOM4 PTPRB EXPH5 ESAM BAIAP2 EDNRB

3.48e-06200916a8adf5902540f6bb15b72efbb9c389b59d67e001
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SHROOM4 PTPRB ESAM TAMALIN DYNC1H1 EDNRB

3.48e-062009165c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellmedial-Endothelial-Capillary_Intermediate_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SHROOM4 PTPRB EXPH5 ESAM BAIAP2 EDNRB

3.48e-062009163ef7b7728615710c691aed8977e2582f19692cf9
ToppCelldistal-2-Endothelial-Capillary_Intermediate_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SHROOM4 PTPRB EXPH5 ESAM BAIAP2 EDNRB

3.48e-062009167a99f28670ffb8ece7873d8a9bcd2a3936d0255d
ToppCellmedial-Endothelial-Capillary_Intermediate_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SHROOM4 PTPRB EXPH5 ESAM BAIAP2 EDNRB

3.48e-06200916707148e01e961097819a05437a842b7d3bf72b0a
ToppCellmetastatic_Lymph_Node-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

CHL1 NWD1 FHOD3 NRIP3 RTN2

1.33e-05148915db046a02a00829910bf9d7dbda068e730aa78f00
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Lypd1_Gpr88|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEC16B EXPH5 NECTIN1 HSD17B13 FHOD3

1.77e-051579155aee90ad7aaa65fdabc23597451da5e48db8f4e6
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BNIP5 EXPH5 AGAP11 TAMALIN CASZ1

2.25e-0516591534fd00be2b28716c871ad9fb356de84a299a0c01
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SHROOM4 PTPRB ZAN ESAM EDNRB

2.82e-05173915ad9777e4ae70b11676ec735eb6db91776ca0cb19
ToppCellE17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PTPRB TRIOBP ESAM TAMALIN EDNRB

3.24e-051789150139b42494c1186390b12106dea7957e2b6717c2
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRB HSD17B13 ESAM FGFR1 TAMALIN

3.24e-05178915375156ba1c7b8592bf733c75f24968161f7cfa09
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-proliferating_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SHROOM4 PTPRB HMCN1 ESAM EDNRB

3.60e-05182915997d37ca2af661c92a56add888762724dfccc890
ToppCellCOPD-Endothelial-VE_Capillary_A|COPD / Disease state, Lineage and Cell class

SHROOM4 KALRN EXPH5 ESAM EDNRB

3.79e-051849155f4f7775d488ececf086c71441defecbee9d8a9c
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CHL1 ESAM TAMALIN CASZ1 EDNRB

4.09e-0518791597b2463fb37e7196dd2f92553acf8e7bc3ec40dd
ToppCellControl-Endothelial-VE_Capillary_A|Control / Disease state, Lineage and Cell class

CHL1 SHROOM4 KALRN ESAM EDNRB

4.09e-0518791554d7588172ac145ff5045ad9771636729ca3f0ca
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 ARHGAP22 NLGN3 RNF180 EDNRB

4.20e-051889157471c194276161422326647f09022e94f3d1640c
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Adult / Lineage, Cell type, age group and donor

CHL1 KALRN ESAM TAMALIN EDNRB

4.20e-05188915e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 ARHGAP22 NLGN3 RNF180 EDNRB

4.20e-05188915053c251d3ddbeb866f34565aefca4535517b4387
ToppCellControl-Endothelial_cells|Control / group, cell type (main and fine annotations)

SHROOM4 PTPRB KALRN TAMALIN EDNRB

4.20e-051889153953b08abfea93468fc8d177bdb16ca7c6ffa1ab
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CHL1 SHROOM4 KALRN ESAM EDNRB

4.31e-05189915b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellCOVID-19-Endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

SHROOM4 PTPRB KALRN ESAM TAMALIN

4.41e-051909159fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CHL1 ESAM TAMALIN CASZ1 EDNRB

4.53e-051919151de0bdfd13bd930691564c2673f2e66393bc0255
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

CHL1 KALRN ESAM TAMALIN EDNRB

4.53e-05191915f229abf69a1217194f74b0502486907e07dba989
ToppCellLPS_only-Endothelial-Endothelial-Vein|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM4 PTPRB HMCN1 KALRN ESAM

4.64e-0519291552acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCellEndothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|World / Lineage, Cell type, age group and donor

CHL1 KALRN ESAM TAMALIN EDNRB

4.64e-051929151e156bab5ecf64627890d2de9b27603d9a01f28d
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CHL1 ESAM TAMALIN CASZ1 EDNRB

4.64e-051929157197e401e563441ab94815f7619e032ebef9e586
ToppCelldroplet-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB HMCN1 ESAM TAMALIN CASZ1

4.64e-0519291542e4dafbe3e8b4a3c25d594f06b95430a1dd8b28
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SF3B1 JADE2 BTBD7 HERC2 EDNRB

4.64e-051929151ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SHROOM4 PTPRB KALRN ESAM EDNRB

4.76e-05193915f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCellCOPD-Endothelial|COPD / Disease state, Lineage and Cell class

SHROOM4 PTPRB KALRN ESAM EDNRB

4.76e-05193915093b28dcccb5841c995d0b33fae0efd6b88f97e0
ToppCellCOVID-19-Endothelial_cells-Inflamed_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

SHROOM4 PTPRB KALRN ESAM TAMALIN

4.76e-05193915979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCellRV-09._Endothelium_I|RV / Chamber and Cluster_Paper

SHROOM4 PTPRB HMCN1 KALRN TAMALIN

4.87e-051949157b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM4 PTPRB KALRN ESAM TAMALIN

4.99e-05195915818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCellLV-09._Endothelium_I|World / Chamber and Cluster_Paper

SHROOM4 PTPRB HMCN1 KALRN TAMALIN

4.99e-0519591519e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

SHROOM4 PTPRB KALRN ESAM TAMALIN

4.99e-0519591550a193475db1bb1e05b8590225a553688c372c14
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SHROOM4 PTPRB KALRN ESAM TAMALIN

5.12e-051969154cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCelldroplet-Lung-30m-Endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPRB HMCN1 ESAM TAMALIN CASZ1

5.12e-0519691558871891185aa7e1e4ab9b99cd25c1ca3c932cc8
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

SHROOM4 PTPRB HMCN1 KALRN TAMALIN

5.24e-05197915ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCellLV-09._Endothelium_I|LV / Chamber and Cluster_Paper

SHROOM4 PTPRB HMCN1 KALRN TAMALIN

5.24e-05197915f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCell3'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LARP6 OLFML1 FGFR1 TSKS EDNRB

5.37e-05198915abac765c4f6864bdb1700bc546c3b9771edc25c3
ToppCellTracheal-NucSeq-Endothelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PTPRB KALRN ESAM TAMALIN EDNRB

5.37e-0519891577e31b6edeeb5ccd5cd3f080898c96bf9ab9f98d
ToppCell5'-Adult-Appendix-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SHROOM4 PTPRB ESAM TAMALIN EDNRB

5.37e-0519891590e85fe7a0ab376a41666dfff6c0e95b7f1c9475
ToppCell3'-Adult-LymphNode-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LARP6 OLFML1 FGFR1 TSKS EDNRB

5.37e-05198915ff57addcbdd53e5d2d0c80ec76b5eab3b3a67ca2
ToppCell3'-Adult-LymphNode-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LARP6 OLFML1 FGFR1 TSKS EDNRB

5.37e-05198915698166b4ca173176ed563af6a1efc8c7d0a18e0b
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Capillary|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SHROOM4 PTPRB ESAM TAMALIN EDNRB

5.50e-051999153fea92affacd4c1f588fa81807df35d6c69b7241
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Capillary-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SHROOM4 PTPRB ESAM TAMALIN EDNRB

5.50e-05199915993999adf346b4fd557989bc53c17eb0ccb996c9
ToppCellcellseq-Endothelial-Endothelial_Vascular-Endothelial_capillary|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SHROOM4 PTPRB ESAM TAMALIN EDNRB

5.50e-051999155f67ea58512856cbdcef759088a5869720a947a8
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SHROOM4 PTPRB ESAM TAMALIN EDNRB

5.50e-051999156cfe5a3d0ad530411ebc11decb4ab4c529e018d5
ToppCellcellseq-Endothelial|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SHROOM4 PTPRB ESAM TAMALIN EDNRB

5.50e-051999154757827efb393c429adec5079d18a173baf23d74
ToppCelldistal-2-Endothelial-Capillary_Aerocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHL1 KALRN EXPH5 ESAM EDNRB

5.50e-05199915bf70c8bfe932bccac5014e55f82019c5148627e7
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SHROOM4 PTPRB ESAM TAMALIN EDNRB

5.50e-05199915ddfb725ccbcadbd188e20b60a7567e1f8245f18d
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SHROOM4 PTPRB HMCN1 ESAM TAMALIN

5.50e-051999159735a1dc10910f02f1106b20ae5ab4c09c21305e
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Capillary|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

SHROOM4 PTPRB ESAM TAMALIN EDNRB

5.50e-0519991589f4db619fbed90f7fdf6ece7a671e514b5c6d76
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_capillary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SHROOM4 PTPRB ESAM FGFR1 BAIAP2

5.50e-05199915772b3f60b83e29b958e1e70dadfd9f058ed4cb7c
ToppCelldistal-3-Endothelial-Capillary_Aerocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHL1 SHROOM4 EXPH5 ESAM EDNRB

5.63e-05200915e12598a097dd9c4cbf9bb85bfa3057722ef73ad5
ToppCellTracheal-10x3prime_v2-Endothelial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SHROOM4 PTPRB ESAM TAMALIN EDNRB

5.63e-052009152e51195810bca8a98488a8a06c538feaa27f1f28
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CHL1 SHROOM4 PTPRB HMCN1 ESAM

5.63e-052009157547d6339f9380d031cfd2cce21ac9a12491e085
ToppCellmedial-Endothelial|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SHROOM4 PTPRB ESAM BAIAP2 EDNRB

5.63e-05200915e889b593c2ae53c42944213ce8672cd886917105
ToppCellmedial-2-Endothelial|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SHROOM4 PTPRB ESAM BAIAP2 EDNRB

5.63e-0520091570440db2d8be1e29aeb34ea5e8ac72641b5c056f
ToppCellLung_Parenchyma-Control-Endothelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SHROOM4 PTPRB KALRN ESAM TAMALIN

5.63e-0520091541ac6adbf61763aa8a81a0ed586c4a5542a42cc5
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SHROOM4 PTPRB ESAM TAMALIN EDNRB

5.63e-0520091530dc7ffef2052ee8610cdca952ca12f240bcec50
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SHROOM4 PTPRB KALRN ESAM TAMALIN

5.63e-052009155109b417c066ecca0252008206b4f4b7a14c8702
ToppCelldistal-2-Endothelial|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SHROOM4 PTPRB ESAM BAIAP2 EDNRB

5.63e-05200915bc1781cff7a4602057a59ef65cf16c3a9459c628
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SHROOM4 PTPRB ESAM TAMALIN EDNRB

5.63e-052009156567683f8f534310fecb44a6721909183fdc15ca
ToppCellParenchyma_Control_(B.)-Endothelial-TX|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

SHROOM4 PTPRB KALRN ESAM TAMALIN

5.63e-052009159e5627e11288713aa9b622aae40e849dd6eacd29
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ZAN PRRC2C ALK HCRTR2

6.17e-05104914b5ca6e589f414e549f4990fe334d4ee54829b298
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGAP22 MAN2B1 ZNF414 TAMALIN

1.55e-04132914a1fda8c5287168c4f159203ed27cadfb4ce1b131
ToppCellMild/Remission-B_intermediate-14|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SHROOM4 SGSM1 EXPH5 HSD17B13

1.64e-041349145bd1e3fa6278facd9e949e9e5e244e700190126b
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CHL1 EXPH5 ESAM EDNRB

1.89e-041399142fdc8f36510aff24abbc79ef2a842db75a85f946
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CHL1 EXPH5 ESAM EDNRB

1.89e-041399145970a654c64e3b54f9d18c102f5b125eec892fc5
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CCNT1 EXPH5 MGA MSTO1

2.73e-04153914553dff9688a1996d8f4ba16e60c683593d781389
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CCNT1 EXPH5 MGA MSTO1

2.73e-0415391488ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCellfacs-Lung-EPCAM-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB ESAM TSKS NRIP3

2.87e-041559140e942609d3e060f1e589fee5997fc6299f3d18bc
ToppCellfacs-Marrow-KLS-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 NECTIN1 FGFR1 MYBPC1

3.01e-041579145d08ff0ba9d3df9cc30f13cab2d2b395ea6f3446
ToppCellfacs-Marrow-KLS-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 NECTIN1 FGFR1 MYBPC1

3.01e-04157914ad9c9b7dfeee3ae46e7e593c51a0407df12195b4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGSM1 HMCN1 FHOD3 CASZ1

3.09e-041589147960337d87afecf2692ab65e5991f052ceddfacc
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM4 KALRN LIN9 EDNRB

3.16e-041599144000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM4 KALRN LIN9 EDNRB

3.16e-041599147619d0d49738dd08daf01b42664691a5323aa793
ToppCellControl-Endothelial_cells-Inflamed_endothelial_cells|Control / group, cell type (main and fine annotations)

SHROOM4 PTPRB TAMALIN EDNRB

3.24e-04160914958256e3d3836160763b82bb48f794087918d935
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Cbln4_Fezf2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEC16B EXPH5 FHOD3 TAMALIN

3.24e-04160914d8241404d775f9a709abdf17988f36293fcf4c58
ToppCellCOVID-19-kidney-Epithelial_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

PTPRB KALRN H3Y1 TAMALIN

3.24e-041609140d4880f85565d8c540c94a8f8109147b3029279a
ToppCellfacs-Lung-EPCAM-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 ESAM TSKS NRIP3

3.39e-041629141f1b93394b1f27cbb76b369c19b9313609edd577
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KALRN EXPH5 NECTIN1 FHOD3

3.47e-041639141e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KALRN EXPH5 NECTIN1 FHOD3

3.47e-04163914431221a41d396b09170476179590eaf8a55266d8
ComputationalGenes in the cancer module 26.

INTS13 NECTIN1 BAIAP2 NRIP3 RTN2 MSTO1

1.82e-04207446MODULE_26
ComputationalGenes in the cancer module 207.

INTS13 NECTIN1 NRIP3 MGA RTN2 MSTO1

2.93e-04226446MODULE_207
DrugMebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Down 200; 4.8uM; PC3; HT_HG-U133A

ARHGAP22 NF1 PTPRB KALRN NADK FGFR1 TSKS MTSS2

9.58e-071998784211_DN
DiseaseLiposarcoma, Pleomorphic

FASN NF1

5.50e-054902C0205825
DiseaseLiposarcoma, Dedifferentiated

FASN NF1

1.37e-046902C0205824
Diseaseliposarcoma

FASN NF1

1.37e-046902C0023827
DiseaseLiposarcoma, well differentiated

FASN NF1

1.37e-046902C1370889
Diseaserenal overload-type gout

SPATA31C2 SPATA31C1

1.37e-046902EFO_0021525
DiseaseGlioma

PMS2 NF1 FGFR1 ALK

1.48e-0487904C0017638
Diseasecancer antigen 15.3 measurement

MTX1 MSTO1

1.91e-047902EFO_0010585
Diseaseeosinophil cationic protein measurement

SPATA31C2 SPATA31C1

2.55e-048902EFO_0010913
Diseasecomparative body size at age 10, self-reported

SEC16B NF1 BTBD7 FGFR1 BAIAP2 ALK HCRTR2

3.05e-04420907EFO_0009819
Diseaselongitudinal alcohol consumption measurement

SPATA31C2 SPATA31C1

3.27e-049902EFO_0007645
DiseaseIntellectual Disability

CHL1 SHROOM4 FASN NF1 TAF1 PQBP1 DYNC1H1

4.43e-04447907C3714756
Diseasesleep disorder (implicated_via_orthology)

NF1 INSRR

4.97e-0411902DOID:535 (implicated_via_orthology)
Diseaseegg allergy measurement, parental genotype effect measurement

SPATA31C2 SPATA31C1

7.02e-0413902EFO_0005939, EFO_0007018
DiseaseMental Retardation, Psychosocial

CHL1 FASN NF1 DYNC1H1

8.81e-04139904C0025363
DiseaseProfound Mental Retardation

CHL1 FASN NF1 DYNC1H1

8.81e-04139904C0020796
DiseaseMental deficiency

CHL1 FASN NF1 DYNC1H1

8.81e-04139904C0917816
DiseaseRhabdomyosarcoma

PMS2 ALK

9.41e-0415902C0035412
Diseasecleft lip (is_implicated_in)

NECTIN1 FGFR1

9.41e-0415902DOID:9296 (is_implicated_in)
Diseaseamygdala volume change measurement

SPATA31C2 SPATA31C1

1.07e-0316902EFO_0021490
Diseaseinsulin measurement

CHL1 UNC5A SGSM1 LARP6 CASZ1

1.37e-03267905EFO_0004467
DiseaseMalignant neoplasm of breast

FASN NF1 PER2 KALRN ELP1 FGFR1 USP54 HERC2 ALK EDNRB

1.61e-0310749010C0006142
Diseaseserum gamma-glutamyl transferase measurement

SEC16B SGSM1 NF1 POM121 KALRN HSD17B13 TRIOBP SKI POM121C

1.90e-03914909EFO_0004532
DiseaseLeukemia, Myelocytic, Acute

NF1 SF3B1 DAPK1 ASXL2

1.97e-03173904C0023467
Diseaseplatelet component distribution width

KALRN JADE2 BTBD7 PRRC2C SKI LIN9 IQCE MYBPC1

2.17e-03755908EFO_0007984
Diseaseurinary albumin to creatinine ratio

PRRC2C MGA CASZ1 MSTO1

2.23e-03179904EFO_0007778
DiseaseCerebral Astrocytoma

NF1 FGFR1

2.64e-0325902C0750935
DiseaseIntracranial Astrocytoma

NF1 FGFR1

2.64e-0325902C0750936
DiseasePilocytic Astrocytoma

NF1 FGFR1

2.64e-0325902C0334583
DiseaseAstrocytoma

NF1 FGFR1

2.64e-0325902C0004114
DiseaseJuvenile Pilocytic Astrocytoma

NF1 FGFR1

2.64e-0325902C0280783
DiseaseDiffuse Astrocytoma

NF1 FGFR1

2.64e-0325902C0280785
Diseaseresponse to gemcitabine

DCP1B DAPK1

2.64e-0325902GO_0036272
DiseaseGrade I Astrocytoma

NF1 FGFR1

2.64e-0325902C1704230
DiseaseSubependymal Giant Cell Astrocytoma

NF1 FGFR1

2.64e-0325902C0205768
DiseaseMixed oligoastrocytoma

NF1 FGFR1

2.64e-0325902C0547065
DiseaseChildhood Cerebral Astrocytoma

NF1 FGFR1

2.64e-0325902C0338070
DiseaseGemistocytic astrocytoma

NF1 FGFR1

2.85e-0326902C0334581
DiseaseProtoplasmic astrocytoma

NF1 FGFR1

2.85e-0326902C0334580
DiseaseFibrillary Astrocytoma

NF1 FGFR1

2.85e-0326902C0334582

Protein segments in the cluster

PeptideGeneStartEntry
STLPSWRKLNGPNQL

DAPK1

971

P53355
QSWPSPAVKGRFKSQ

ANKLE2

871

Q86XL3
TIKVPGKWPSLATSA

AGAP11

176

Q8TF27
TKANPWIGNSLKPDS

AKR7L

76

Q8NHP1
LKAGEQLSWPAPSTK

CASZ1

246

Q86V15
ATAWQAPRKPLATKA

H3Y2

11

P0DPK5
STQDTGKLPVKWTAP

CSK

341

P41240
KTLWPKGSNASLARS

EDNRB

51

P24530
GKRWLSSQPSFKLEP

CCNT1

331

O60563
VNTGFTKNPSTRLWP

HSD17B13

221

Q7Z5P4
IPQDRLWSPSSKGTQ

CCDC157

621

Q569K6
WKRKVSSSSPQSGCP

ASXL2

131

Q76L83
NRWKPNSSKVLGRSP

CDCA3

186

Q99618
SGTWSQGTKKLITLP

NWD1

686

Q149M9
APKNTTKSWQGRILG

RBM19

376

Q9Y4C8
PQKLWLGTAKPGSLT

IQCE

76

Q6IPM2
KSKGPVSLLSLWSNR

INTS13

646

Q9NVM9
SSKWAQFVLPPRKSS

MRNIP

226

Q6NTE8
NKQIWLSSPSSGPKR

FXN

151

Q16595
EKKSSWPSQAAPSLR

CDIPTOSP

11

P0DO92
GSLTSLKVKWQRPPG

PTPRB

301

P23467
LQKTPVWKGRNTSSA

LIN9

36

Q5TKA1
TATLSWGLPKKLNGN

CHL1

931

O00533
LSSKWLPSSPSGVAK

MGA

441

Q8IWI9
SPKDKWQPLLSTVTG

HERC2

1601

O95714
WSTSKPASAGKLPAQ

HERC2

4316

O95714
PGKPWQTKLSSAGLI

MYG1

121

Q9HB07
SKLPSSTKSGWPRQN

JADE2

31

Q9NQC1
ATAWQAPRKPLATKA

H3Y1

11

P0DPK2
QDPASQRLTWNKSPK

NADK

91

O95544
PGLRNTSGIDSPWKK

PER2

776

O15055
AKASPKRLSLPNTAW

MTSS2

631

Q765P7
WRVKSIPNGKGSSPL

MSTO1

131

Q9BUK6
NIIWTSSSLGPKRKA

CSNKA2IP

196

A0A1B0GTH6
SSPGPKRSTNTLKKW

KALRN

1756

O60229
KSGNLWTRLGSAPKT

NCBP3

541

Q53F19
TQGRLWKPSFLKNPG

EXPH5

1906

Q8NEV8
PWSSPLAQRKGVSRK

LARP6

381

Q9BRS8
NSKLAWTLRSPPTGA

KRT87P

226

A6NCN2
WKPSGSLIASTQDKP

ELP1

246

O95163
RKGSGFRWKNLSQSP

TAMALIN

81

Q7Z6J2
KPAPRKQILTLSWQG

OLFML1

201

Q6UWY5
EATGIPKPSINWRKN

HMCN1

3826

Q96RW7
YSQKPPKRASSQLSW

PARP16

271

Q8N5Y8
SQLWKRNGPSSSPFS

POM121C

401

A8CG34
TWSTGLPKRNEAKTG

PQBP1

216

O60828
RGISQLWKRNGPSSS

POM121

421

Q96HA1
RPNGKTWSTKRPAIS

NLGN3

661

Q9NZ94
PGTSSVVQRKWKPLQ

HCRTR2

256

O43614
TGKPLESWINKTPNT

DCP1B

486

Q8IZD4
PSEQRPSQDTKKGWL

BNIP5

86

P0C671
SGTPNPTLRWLKNGK

FGFR1

181

P11362
PSNSNISKGESRPKW

DHX57

76

Q6P158
WSPALKTQGKLNTRP

CRYBG2

971

Q8N1P7
GWSQVPRGQPTFTKK

FHOD3

876

Q2V2M9
PTTEGGKSNAWLRQK

BTBD7

551

Q9P203
PWPKSSDTISKNGTL

ESAM

296

Q96AP7
SRLKWTTNTGPTPHQ

MAN2B1

966

O00754
SPWKVTSINKSPQRD

INSRR

726

P14616
TAKGRQNISPDKIPW

DYNC1H1

4226

Q14204
GKLSPDAIPGKWTSQ

FASN

1581

P49327
QKSNSAKWPLPSCRK

RNF180

506

Q86T96
LKVHKISNPWQSPSG

MTX1

186

Q13505
LRSGPRVPWASKTNK

NRIP3

76

Q9NQ35
LKWAKSPRSSGVPSL

RTN2

321

O75298
QAKGKPRPWQSSTST

SPATA31C2

481

B4DYI2
TKPQRASLAGWLPSS

TAF1

426

P21675
KSKSETRWGPRPSSN

PRRC2C

986

Q9Y520
LAPGNTWKPRKLTVQ

SHROOM4

951

Q9ULL8
SQAKGKPRPWQSSTS

SPATA31C1

486

P0DKV0
KPSSWLRTLAGSSNK

SKI

351

P12755
STQWPKIKVTRGPAT

TRIOBP

1661

Q9H2D6
KVQTLPSWKSSFRQP

ARHGAP22

421

Q7Z5H3
SPWADRKAAQPKSLS

BAIAP2

311

Q9UQB8
KVHGSRNKPTSLWNP

ALK

1491

Q9UM73
VWKKSQGAGSSPRRP

ZNF414

286

Q96IQ9
KSQGVKRGWLSVPTS

nan

111

Q6ZSN1
QTPGATPKKLSSWDQ

SF3B1

206

O75533
WVGSSSPISKEKLPN

TMEM186

36

Q96B77
RTLKETQPWSSPKGS

NF1

2486

P21359
KQKPEAGLSWNSLGP

TSKS

261

Q9UJT2
SNLPSLWQPSPRKSS

SGSM1

496

Q2NKQ1
SWFRSKPTKNASPAG

SEC16B

916

Q96JE7
PSPDSWSLRLKKQSC

UNC5A

526

Q6ZN44
KLISLPTSKNWTFGP

PMS2

766

P54278
TQKTIWTQGPSPRKA

TIMM21

61

Q9BVV7
TPQSKSPPVRKSNWR

ZC2HC1B

66

Q5TFG8
VRPKTSSKWSAPGSA

UBR3

1061

Q6ZT12
NWATRKPPAPKSTQE

TIAL1

171

Q01085
LKAQKPSPSWTRSIA

ZNF487

411

B1APH4
RQGLPKAPGWTEKNS

USP54

971

Q70EL1
CQSQGLKPPLWRNSS

ZAN

2191

Q9Y493
LNCSVRGNPKPKITW

MYBPC1

1066

Q00872
NGKPPSVVSWETRLK

NECTIN1

176

Q15223