Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	axon terminus	ITGA2 HCN4 GRM7 SYT11 MPP4	6.88e-05	210	43	5	GO:0043679
GeneOntologyCellularComponent	neuron projection terminus	ITGA2 HCN4 GRM7 SYT11 MPP4	1.12e-04	233	43	5	GO:0044306
GeneOntologyCellularComponent	presynaptic membrane	CADM1 STXBP1 GRM7 SYT11 MPP4	2.51e-04	277	43	5	GO:0042734
GeneOntologyCellularComponent	presynaptic active zone membrane	STXBP1 GRM7 SYT11	5.54e-04	78	43	3	GO:0048787
GeneOntologyCellularComponent	terminal bouton	HCN4 GRM7 SYT11	1.01e-03	96	43	3	GO:0043195
GeneOntologyCellularComponent	basal part of cell	CADM1 ITGA2 HCN4 MPP4 ERBIN	1.03e-03	378	43	5	GO:0045178
GeneOntologyCellularComponent	endocytic vesicle	DPP4 NCF2 STXBP1 SYT11 CEMIP	1.11e-03	384	43	5	GO:0030139
GeneOntologyCellularComponent	axonemal dynein complex	DNAH3 DNAH17	1.20e-03	25	43	2	GO:0005858
GeneOntologyCellularComponent	distal axon	ITGA2 HCN4 GRM7 SYT11 MPP4	1.91e-03	435	43	5	GO:0150034
GeneOntologyCellularComponent	integrin complex	ITGA2 ITGB8	1.97e-03	32	43	2	GO:0008305
GeneOntologyCellularComponent	presynapse	CADM1 ITGA2 STXBP1 HCN4 GRM7 SYT11 MPP4	2.04e-03	886	43	7	GO:0098793
GeneOntologyCellularComponent	axon	CADM1 ITGA2 STXBP1 HCN4 GRM7 SYT11 MPP4	2.10e-03	891	43	7	GO:0030424
GeneOntologyCellularComponent	perinuclear region of cytoplasm	MALT1 ITGA2 STXBP1 SBF1 FASLG HCN4 SYT11	2.74e-03	934	43	7	GO:0048471
GeneOntologyCellularComponent	presynaptic active zone	STXBP1 GRM7 SYT11	3.04e-03	141	43	3	GO:0048786
GeneOntologyCellularComponent	phagocytic vesicle	NCF2 STXBP1 SYT11	4.12e-03	157	43	3	GO:0045335
Domain	Integrin_dom	ITGA2 ITGB8	1.37e-03	25	41	2	IPR032695
Domain	Znf_C3HC4_RING-type	RNF213 RNF2 LTN1	6.33e-03	172	41	3	IPR018957
Pathway	REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI	ST6GAL1 MGAT3 MGAT5	4.50e-05	26	38	3	M979
Pathway	REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI	ST6GAL1 MGAT3 MGAT5	6.29e-05	29	38	3	MM15699
Pubmed	Diverse expression of N-acetylglucosaminyltransferase V and complex-type β1,6-branched N-glycans in uveal and cutaneous melanoma cells.	MGAT3 MGAT5	1.49e-06	2	43	2	26098720
Pubmed	Glycosylation regulates NK cell-mediated effector function through PI3K pathway.	MGAT3 MGAT5	1.49e-06	2	43	2	20089585
Pubmed	Altered β1,6-GlcNAc and bisecting GlcNAc-branched N-glycan on integrin β1 are associated with early spontaneous miscarriage in humans.	MGAT3 MGAT5	1.49e-06	2	43	2	26109616
Pubmed	Glycoprotein glycosylation and cancer progression.	MGAT3 MGAT5	4.48e-06	3	43	2	10580127
Pubmed	The role of N-acetylglucosaminyltransferase III and V in the post-transcriptional modifications of E-cadherin.	MGAT3 MGAT5	4.48e-06	3	43	2	19403558
Pubmed	Overexpression of N-acetylglucosaminyltransferases III and V in human melanoma cells. Implications for MCAM N-glycosylation.	MGAT3 MGAT5	4.48e-06	3	43	2	24726881
Pubmed	E-cadherin and adherens-junctions stability in gastric carcinoma: functional implications of glycosyltransferases involving N-glycan branching biosynthesis, N-acetylglucosaminyltransferases III and V.	MGAT3 MGAT5	4.48e-06	3	43	2	23671930
Pubmed	A genetic approach to Mammalian glycan function.	ST6GAL1 MGAT3 MGAT5	6.98e-06	30	43	3	12676797
Pubmed	Reduction of the ST6 β-galactosamide α-2,6-sialyltransferase 1 (ST6GAL1)-catalyzed sialylation of nectin-like molecule 2/cell adhesion molecule 1 and enhancement of ErbB2/ErbB3 signaling by microRNA-199a.	ST6GAL1 CADM1	8.94e-06	4	43	2	23504322
Pubmed	Glycosylation-dependent lectin-receptor interactions preserve angiogenesis in anti-VEGF refractory tumors.	ST6GAL1 MGAT5	8.94e-06	4	43	2	24529377
Pubmed	N‑glycosylation and receptor tyrosine kinase signaling affect claudin‑3 levels in colorectal cancer cells.	ST6GAL1 MGAT5	8.94e-06	4	43	2	32945502
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	RNF213 ST6GAL1 CADM1 MGAT5 ITGA2 IL1RAP ITGB8 SDHB LTN1	1.33e-05	1201	43	9	35696571
Pubmed	The absence of core fucose up-regulates GnT-III and Wnt target genes: a possible mechanism for an adaptive response in terms of glycan function.	MGAT3 MGAT5	2.23e-05	6	43	2	24619415
Pubmed	APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints.	ITGB8 INPP5D	5.35e-05	9	43	2	37749326
Pubmed	Genetic control of susceptibility to infection with Mycobacterium tuberculosis in mice.	NCF2 FASLG	6.68e-05	10	43	2	11197687
Pubmed	Alpha9 and beta8 integrin expression correlates with the merger of the developing mouse eyelids.	ITGA2 ITGB8	9.78e-05	12	43	2	10090148
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	ST6GAL1 MGAT3 SBF1 ZNF804B	1.08e-04	199	43	4	23382691
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH3 DNAH17	1.35e-04	14	43	2	9373155
Pubmed	Analysis of common germline polymorphisms as prognostic factors in patients with lymph node-positive breast cancer.	ITGA2 FASLG	1.35e-04	14	43	2	20204402
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ITGA2 STXBP1 SBF1 ERBIN PIK3R3	1.67e-04	421	43	5	36976175
Pubmed	Genetic influences on the end-stage effector phase of arthritis.	NCF2 FASLG	1.77e-04	16	43	2	11489951
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	RNF213 RNF2 LTN1	2.25e-04	95	43	3	29643511
Pubmed	Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor.	ITGA2 FASLG	2.52e-04	19	43	2	16973387
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	NLN ERBIN CEMIP	2.86e-04	103	43	3	10574462
Pubmed	A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.	RNF2 UBE2L6 LTN1	4.26e-04	118	43	3	19690564
Pubmed	Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.	ITGA2 ITGB8	5.14e-04	27	43	2	31541017
Pubmed	Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development.	NLN PIK3R3	6.35e-04	30	43	2	38310234
Pubmed	Identification of interaction partners for individual SH3 domains of Fas ligand associated members of the PCH protein family in T lymphocytes.	FASLG INPP5D	6.79e-04	31	43	2	19041431
Pubmed	Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women.	IL1RAP ZNF804B	7.69e-04	33	43	2	20966902
Pubmed	A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins.	ST6GAL1 MGAT3	7.69e-04	33	43	2	23118208
Pubmed	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	COLGALT2 SDHB	8.17e-04	34	43	2	20189936
Pubmed	BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62.	RNF213 UBE2L6 SDHB	9.58e-04	156	43	3	32850835
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	CDK11A PIK3R3 DNAH17 LTN1	1.04e-03	363	43	4	25036637
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	MALT1 CADM1 IL1RAP	1.07e-03	162	43	3	25826454
Pubmed	Defining the molecular character of the developing and adult kidney podocyte.	DPP4 MGAT5	1.07e-03	39	43	2	21931791
Pubmed	Rab11-FIP1 and Rab11-FIP5 Regulate pIgR/pIgA Transcytosis through TRIM21-Mediated Polyubiquitination.	ZNF202 SDHB	1.19e-03	41	43	2	34638806
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	STXBP1 IL1RAP SYT11 ERBIN	1.20e-03	377	43	4	38117590
Cytoband	Ensembl 112 genes in cytogenetic band chr1q25	NCF2 COLGALT2 RNF2 RALGPS2	1.87e-05	167	43	4	chr1q25
Cytoband	5q12.3	NLN ERBIN	1.30e-04	18	43	2	5q12.3
Cytoband	1q25	NCF2 COLGALT2	2.75e-04	26	43	2	1q25
Cytoband	11q22.3	CWF19L2 ALKBH8	7.91e-04	44	43	2	11q22.3
Cytoband	Ensembl 112 genes in cytogenetic band chr5q12	NLN ERBIN	1.77e-03	66	43	2	chr5q12
Cytoband	17q25.3	RNF213 DNAH17	4.08e-03	101	43	2	17q25.3
Cytoband	Ensembl 112 genes in cytogenetic band chr11q22	CWF19L2 ALKBH8	4.57e-03	107	43	2	chr11q22
GeneFamily	Mannosyl-glycoprotein N-acetylglucosaminyltransferases	MGAT3 MGAT5	1.23e-04	9	34	2	435
GeneFamily	Dyneins, axonemal	DNAH3 DNAH17	4.59e-04	17	34	2	536
GeneFamily	Immunoglobulin like domain containing	MALT1 CADM1 IL1RAP	5.62e-03	193	34	3	594
GeneFamily	Ring finger proteins	RNF213 RNF2 LTN1	1.47e-02	275	34	3	58
GeneFamily	SH2 domain containing	INPP5D PIK3R3	1.54e-02	101	34	2	741
Coexpression	GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_DN	MALT1 NCF2 STXBP1 IL1RAP DNAH17	1.51e-05	196	42	5	M8717
Coexpression	GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_UP	MGAT5 HIBADH ITGB8 SDHB CEMIP	1.66e-05	200	42	5	M4332
Coexpression	MURARO_PANCREAS_DUCTAL_CELL	RNF213 NLN NCF2 ST6GAL1 MGAT5 ITGA2 UBE2L6 ERBIN ITGB8 SDHB	2.55e-05	1276	42	10	M39173
CoexpressionAtlas	kidney_adult_Podocyte_MafB_top-relative-expression-ranked_200	DPP4 MALT1 MGAT5 ITGA2 ITGB8	2.36e-05	179	41	5	gudmap_kidney_adult_Podocyte_MafB_200
CoexpressionAtlas	kidney_adult_RenCorpuscGlomer_k-means-cluster#2_top-relative-expression-ranked_1000	DPP4 MALT1 MGAT5 ITGA2 ITGB8	7.32e-05	227	41	5	gudmap_kidney_adult_RenCorpuscGlomer_k2_1000
CoexpressionAtlas	kidney_adult_Podocyte_MafB_k-means-cluster#1_top-relative-expression-ranked_200	MALT1 MGAT5 ITGA2 ITGB8	8.91e-05	122	41	4	gudmap_kidney_adult_Podocyte_MafB_k1_200
CoexpressionAtlas	kidney_adult_JuxtaGlom_Ren1_k-means-cluster#2_top-relative-expression-ranked_500	DPP4 ITGB8	1.01e-04	8	41	2	gudmap_kidney_adult_JuxtaGlom_Ren1_k2_500
CoexpressionAtlas	kidney_adult_RenCorpuscGlomer_k-means-cluster#3_top-relative-expression-ranked_500	DPP4 MGAT5 ITGA2 ITGB8	1.56e-04	141	41	4	gudmap_kidney_adult_RenCorpuscGlomer_k3_500
CoexpressionAtlas	kidney_adult_Podocyte_MafB_top-relative-expression-ranked_1000	DPP4 MALT1 NCF2 ST6GAL1 MGAT5 ITGA2 ITGB8 CYP27A1	1.71e-04	838	41	8	gudmap_kidney_adult_Podocyte_MafB_1000
CoexpressionAtlas	kidney_adult_Podocyte_MafB_top-relative-expression-ranked_500	DPP4 MALT1 ST6GAL1 MGAT5 ITGA2 ITGB8	1.98e-04	445	41	6	gudmap_kidney_adult_Podocyte_MafB_500
ToppCell	COVID-19-Heart-Neuronal\|Heart / Disease (COVID-19 only), tissue and cell type	CADM1 ITGA2 IL1RAP ITGB8 RALGPS2	6.78e-07	173	43	5	6fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell	COVID-19_Severe-gd_T\|COVID-19_Severe / Disease condition and Cell class	RNF213 CADM1 SYT11 ERBIN PIK3R3	9.19e-07	184	43	5	791f1bcb954aadc63d4117c400537d036f68734d
ToppCell	facs-Marrow-T-cells-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MALT1 ST6GAL1 ITGA2 FASLG RALGPS2	9.44e-07	185	43	5	e1fd0a807def8c2127194108b1a30c6de7024292
ToppCell	AT2_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	DPP4 ST6GAL1 CADM1 ITGA2 STXBP1	1.29e-06	197	43	5	5e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NCF2 MGAT3 IL1RAP ITGB8 CYP27A1	1.39e-06	200	43	5	a443e475e7a10c26a6173d1af961de6219e0e567
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NCF2 MGAT3 IL1RAP ITGB8 CYP27A1	1.39e-06	200	43	5	ed785a6d08ca2b350dc3307b587eadfb2886d1f9
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-B_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MGAT5 FASLG INPP5D RALGPS2	1.93e-05	165	43	4	7039bb5a7af4684fbd1192230864e5cd6936e83c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-B_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MGAT5 FASLG INPP5D RALGPS2	1.93e-05	165	43	4	d2c79653710b139794170f3d72f11392fc548ac7
ToppCell	Control-B_cells-Activated_B_cells\|Control / group, cell type (main and fine annotations)	ST6GAL1 MGAT5 INPP5D RALGPS2	2.07e-05	168	43	4	a7159a35fe37f8c241cf8d391debe271e0698105
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM1 ITGA2 IL1RAP SYT11	2.07e-05	168	43	4	95dc690c1987b05685d36e6bb20eb79308696e30
ToppCell	COVID-19-kidney-Bcells\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ST6GAL1 MGAT5 INPP5D RALGPS2	2.21e-05	171	43	4	8e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCell	Control-B_cells-B_cells\|Control / group, cell type (main and fine annotations)	ST6GAL1 MGAT5 INPP5D RALGPS2	2.48e-05	176	43	4	d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCell	COVID-19-B_cells-Activated_B_cells\|COVID-19 / group, cell type (main and fine annotations)	ST6GAL1 MGAT5 INPP5D RALGPS2	2.53e-05	177	43	4	653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCell	IPF-Lymphoid-B\|World / Disease state, Lineage and Cell class	ST6GAL1 MGAT5 INPP5D RALGPS2	2.71e-05	180	43	4	30f9398c9b784f49470847a025bac90687e997a1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ST6GAL1 MGAT5 INPP5D RALGPS2	2.71e-05	180	43	4	65c069585737302a69b9a01476f4eb8b50cb2bfd
ToppCell	Control-Myeloid-Alveolar_macrophages\|Control / group, cell type (main and fine annotations)	NCF2 IL1RAP ITGB8 CYP27A1	2.77e-05	181	43	4	8d2102c8c86c59a82610f26f90946b290552e666
ToppCell	Control-Lymphoid-B\|World / Disease state, Lineage and Cell class	ST6GAL1 MGAT5 INPP5D RALGPS2	2.77e-05	181	43	4	9124f1a610cfc3355ad87921cd3eb5346956475d
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B-B\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ST6GAL1 MGAT5 INPP5D RALGPS2	2.77e-05	181	43	4	8d8cc4dae2c8bd5f4b1c159f2a52edc4c9449c86
ToppCell	pdx-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	MALT1 COLGALT2 ITGA2 CEMIP	2.83e-05	182	43	4	7b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell	droplet-Mammary_Gland-nan-21m-Lymphocytic-B_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 ST6GAL1 INPP5D RALGPS2	2.83e-05	182	43	4	97f393549c7718a32af55b2377801bfebb10cc52
ToppCell	IPF-Lymphoid-B\|IPF / Disease state, Lineage and Cell class	ST6GAL1 MGAT5 INPP5D RALGPS2	2.89e-05	183	43	4	e37d2c015c34471a8a54a0299e94b0371e1ada5a
ToppCell	nucseq-Immune-Lymphocytic_B\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ST6GAL1 MGAT5 INPP5D RALGPS2	2.95e-05	184	43	4	911658e7bb499c1bbc8419eec8ff88729bc39a75
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ST6GAL1 MGAT5 INPP5D RALGPS2	2.95e-05	184	43	4	942b58ae7172bb5f97e55b032db9329d161854af
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MALT1 ST6GAL1 FASLG RALGPS2	2.95e-05	184	43	4	b12fb85a064f715a4f0ada1df8e422c359b573cf
ToppCell	COPD-Lymphoid-B\|COPD / Disease state, Lineage and Cell class	ST6GAL1 MGAT5 INPP5D RALGPS2	3.01e-05	185	43	4	925e79c35c381dd44ec5fb921dca09ce43140135
ToppCell	COPD-Lymphoid-B\|World / Disease state, Lineage and Cell class	ST6GAL1 MGAT5 INPP5D RALGPS2	3.01e-05	185	43	4	22891ed75e25ef30dfa541cb82d85e08ce07e7d9
ToppCell	Children_(3_yrs)-Immune-B_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ST6GAL1 MGAT5 INPP5D RALGPS2	3.08e-05	186	43	4	aa576748921a318798b911a611f05319b95e8d5e
ToppCell	5'-Adult-Appendix-Hematopoietic-B_cells-Memory_B\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST6GAL1 MGAT5 INPP5D RALGPS2	3.08e-05	186	43	4	b5e094850ac3785775393cd78a939b02339732b0
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CADM1 ITGA2 SYT11 ITGB8	3.08e-05	186	43	4	6f88b68735d0f7c9904eb8413e6007910d556185
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-B_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ST6GAL1 MGAT5 INPP5D RALGPS2	3.14e-05	187	43	4	8fa454dc4e6a3e8e2bb2ad803acc579e0d3f76da
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-B_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ST6GAL1 MGAT5 INPP5D RALGPS2	3.14e-05	187	43	4	edad646d5eb1d70b768dc21fe02ef5265214e8e6
ToppCell	5'-Adult-Appendix-Hematopoietic-B_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST6GAL1 MGAT5 INPP5D RALGPS2	3.21e-05	188	43	4	7b56c680e9f1851cb961b0f8faeeb987685ae36d
ToppCell	B_cells-Naive_B_cells_\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ST6GAL1 MGAT5 INPP5D RALGPS2	3.21e-05	188	43	4	d1bc1316bbb8cfc39acc70f8680b14d19f536997
ToppCell	Children_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MGAT3 IL1RAP ITGB8 CYP27A1	3.21e-05	188	43	4	d7a9fb5b021e127b8d927658a55a71098d513b5c
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	DPP4 CADM1 STXBP1 ACTR3C	3.27e-05	189	43	4	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NCF2 IL1RAP ITGB8 CYP27A1	3.27e-05	189	43	4	a59025e82fabd9d60e2438dee85b2644478cc7c8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RNF213 DPP4 GRM7 ITGB8	3.27e-05	189	43	4	aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RNF213 DPP4 GRM7 ITGB8	3.27e-05	189	43	4	8977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCell	390C-Myeloid-Macrophage-FABP4+_Macrophage_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	NCF2 MGAT3 ITGB8 CYP27A1	3.27e-05	189	43	4	3b5e1a8d5c1e1fa2124f64f212e9c6b8f1b7d7da
ToppCell	IPF-Myeloid-Macrophage_Alveolar\|IPF / Disease state, Lineage and Cell class	NCF2 MGAT3 ITGB8 CYP27A1	3.34e-05	190	43	4	e539ebc0f4c5ee5dba86c614387be7d91338ad47
ToppCell	Fetal_29-31_weeks-Immune-B_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ST6GAL1 MGAT5 INPP5D RALGPS2	3.41e-05	191	43	4	84452125d1b5b76974e3f9126f611eff16d45c25
ToppCell	Control-Myeloid-Macrophage_Alveolar\|Myeloid / Disease state, Lineage and Cell class	MGAT3 MGAT5 ITGB8 CYP27A1	3.41e-05	191	43	4	a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-memory_B_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ST6GAL1 MGAT5 INPP5D RALGPS2	3.63e-05	194	43	4	f0c113edb706d53792892115b67277a285219942
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical\|TCGA-Thryoid / Sample_Type by Project: Shred V9	DPP4 MGAT3 ITGA2 IL1RAP	3.63e-05	194	43	4	b46c54802b8d1e0a0a17f9ed8e82eaf5e7f4849d
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_cell-B_mature\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ST6GAL1 MGAT5 INPP5D RALGPS2	3.70e-05	195	43	4	3311a1bf4ed94820b45047d44fc14b14ac72e6fb
ToppCell	Macrophages-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	CWF19L2 NCF2 ITGB8 CYP27A1	3.70e-05	195	43	4	e48bf57e6da23fbb4637a02387155f825455c49f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CADM1 STXBP1 GRM7 CEMIP	3.70e-05	195	43	4	787e95fb59c40bba784544b662fac37606ae1427
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CADM1 ACTR3C ITGB8 RALGPS2	3.77e-05	196	43	4	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CADM1 ACTR3C ITGB8 RALGPS2	3.77e-05	196	43	4	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	Children_(3_yrs)-Immune\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NCF2 MGAT5 INPP5D CYP27A1	3.85e-05	197	43	4	f18807124b91310fcd84238484a80ecdba684679
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ST6GAL1 MGAT5 INPP5D RALGPS2	3.85e-05	197	43	4	da61afba697ec49ca86e062d35a825280da558ac
ToppCell	AT2_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	DPP4 CADM1 ITGA2 STXBP1	3.85e-05	197	43	4	8b5d4e1c33a57c899c51feb9a6f347232f8910a3
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NCF2 MGAT3 ITGB8 CYP27A1	3.93e-05	198	43	4	e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NCF2 MGAT3 ITGB8 CYP27A1	3.93e-05	198	43	4	0baeb8e2c199ff10bb5c829c523546af3c9227c1
ToppCell	mLN-(2)_B_cell-(22)_B_cell_memory\|mLN / shred on region, Cell_type, and subtype	ST6GAL1 MGAT5 INPP5D RALGPS2	3.93e-05	198	43	4	4d189df1db5b41306e9653436d7d7e75ff5afa06
ToppCell	mLN-B_cell-B_cell_memory\|mLN / Region, Cell class and subclass	ST6GAL1 MGAT5 INPP5D RALGPS2	3.93e-05	198	43	4	6dc155ee487abb1319a60a7a70e84c28c9851985
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SBF1 IL1RAP SYT11 ERBIN	4.08e-05	200	43	4	0e85c90719d9ec51a566e230c9dd2909d8df1f52
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Cortical_neuron\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	CADM1 STXBP1 UBE2L6 HIBADH	4.08e-05	200	43	4	458fb0f40c1720f1cacedf78c40bd059692bfc62
ToppCell	Parenchyma_COVID-19-Immune-TX-TRAM-3\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	NCF2 CYP27A1 OSGIN1	2.99e-04	135	43	3	4c3a54465af2f6f0cd2a06dc5ce6f760100f37cc
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	DPP4 ALKBH8 GRM7	3.39e-04	141	43	3	c7043f3b024bb16bbc89e33075f5b6ced5cb9185
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-MAIT\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MALT1 FASLG INPP5D	3.99e-04	149	43	3	f4bee5fdaaa4a1917e403de90e5a62353006df24
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MALT1 ITGA2 SYT11	3.99e-04	149	43	3	7e295b2b82dea0754e98f8cef788e2781e5d641f
ToppCell	Leuk-UTI-Lymphocyte-T_NK-dnT\|Leuk-UTI / Disease, Lineage and Cell Type	CADM1 ITGA2 PIK3R3	3.99e-04	149	43	3	53f145cf7089d948d41aa3c443e983e011826836
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MALT1 ITGA2 SYT11	3.99e-04	149	43	3	b4f77dc5f9d08b249fe5cd9a0acf86308c528ef4
ToppCell	normal_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	COLGALT2 DNAH17 PIGM	3.99e-04	149	43	3	a34d095b8e0fe59d69d84e4fd2fe4ccb82f92e4f
ToppCell	E16.5-samps-Myeloid\|E16.5-samps / Age Group, Lineage, Cell class and subclass	NCF2 INPP5D CYP27A1	4.56e-04	156	43	3	c7c73cef5700b0ae75280e62c94728434c712537
ToppCell	droplet-Heart-nan-24m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAT3 ALKBH8 GRM7	4.82e-04	159	43	3	7ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCell	5'-Adult-LymphNode-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF213 ST6GAL1 CADM1	4.91e-04	160	43	3	e44b3c74c76b4632ada7f5bd6d09434b02d79743
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CWF19L2 DNAH3 GRM7	4.91e-04	160	43	3	8374ae912337947b2cc8d17d5840f306361fe1ff
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RNF213 NCF2 INPP5D	5.00e-04	161	43	3	5a8698790f9aba796dd2b64af419055c60bd7de8
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	CDK11A ERBIN INPP5D	5.09e-04	162	43	3	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	390C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	COLGALT2 ITGA2 FASLG	5.09e-04	162	43	3	45be019b50e3727fc9d3fad2ff78e74e4f2d746b
ToppCell	390C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	COLGALT2 ITGA2 FASLG	5.09e-04	162	43	3	fbb0cc2b1434a340dc35058b77c73ea61004c252
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CADM1 CYP27A1 CEMIP	5.18e-04	163	43	3	bca9abd02ffb2a90c8386a59f5e25126ae7b6acd
ToppCell	Adult-Immune-B_cell-D231\|Adult / Lineage, Cell type, age group and donor	ST6GAL1 INPP5D RALGPS2	5.18e-04	163	43	3	4f5821299b265663c7d0352b28285f56e1988841
ToppCell	droplet-Fat-Gat-18m-Myeloid-monocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 IL1RAP OSGIN1	5.18e-04	163	43	3	3d12a8ca97005308403a3ab136af483ab25f9b0e
ToppCell	Basal_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	ITGA2 SYT11 CEMIP	5.27e-04	164	43	3	85487a303194f5244956ec1ca2d1758d38117f41
ToppCell	facs-BAT-Fat-3m-Lymphocytic-NK_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MALT1 ITGA2 FASLG	5.27e-04	164	43	3	cbdb7e893cb3959b9920c0c7c535ace03a5f4986
ToppCell	facs-Heart-LA-18m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 CADM1 INPP5D	5.37e-04	165	43	3	be7e18d798e81e4b0f3080054aa222c6913e350b
ToppCell	facs-Heart-LA-18m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 CADM1 INPP5D	5.37e-04	165	43	3	941a5b95164eaea47c3e6376e358f94c15b98312
ToppCell	LV-16._Neuronal\|World / Chamber and Cluster_Paper	CADM1 ITGA2 ITGB8	5.37e-04	165	43	3	6ed52cb756d21addf46c7f6c457458b01339fe04
ToppCell	droplet-Bladder-nan-3m-Hematologic-granulocyte-monocyte_progenitor\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 NCF2 INPP5D	5.46e-04	166	43	3	e01c720de6d4ca144c55378e023e718a64bf32f6
ToppCell	facs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MALT1 ST6GAL1 SBF1	5.56e-04	167	43	3	528493896aebe7d03d4b6ad2341b12927859e2e4
ToppCell	facs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MALT1 ST6GAL1 SBF1	5.56e-04	167	43	3	a82e85caf79395baa48380786d9df32a86dfd1ce
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CADM1 CYP27A1 CEMIP	5.66e-04	168	43	3	63437b3c3a66f953eaed600965ab193f9cc49da2
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l34\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPP4 NCF2 INPP5D	5.66e-04	168	43	3	84977db9d71e59208727885320cc18d80d064380
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CADM1 IL1RAP ITGB8	5.66e-04	168	43	3	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	5'-Adult-LymphNode-Hematopoietic-Plasma_cells-IgG_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF213 ST6GAL1 CADM1	5.66e-04	168	43	3	f5a18123f84c62211d9279e9c41e90122e4c4895
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8\|TCGA-Thryoid / Sample_Type by Project: Shred V9	CADM1 IL1RAP SYT11	5.66e-04	168	43	3	00646601548b0fee42ae16bfa5e93603bc7c5129
ToppCell	LV-16._Neuronal\|LV / Chamber and Cluster_Paper	CADM1 ITGA2 ITGB8	5.75e-04	169	43	3	a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCell	droplet-Lung-nan-18m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 CADM1 CYP27A1	5.75e-04	169	43	3	149a4f83da15bdeb170e980fb5b5b1af89ae07a6
ToppCell	Basal_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	ITGA2 IL1RAP CEMIP	5.85e-04	170	43	3	776d4224a682b6c648041827efd69794f88906f0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ST6GAL1 INPP5D RALGPS2	5.85e-04	170	43	3	a965e3ee6818790a4a6916824fde64333d9b11b7
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPP4 CADM1 CYP27A1	5.85e-04	170	43	3	bf589c4297ccc90e5f51e3d0fcc229548af4fcef
ToppCell	facs-BAT-Fat-3m-Myeloid-granulocyte\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 IL1RAP OSGIN1	5.85e-04	170	43	3	8fd0a55266066a51266ab616c38c883e2680bcf4
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IL1RAP GRM7 ZNF804B	5.85e-04	170	43	3	49fc45d8a5c3ad89d1649fa46d7a285891379392
ToppCell	Children_(3_yrs)-Immune-B_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ST6GAL1 INPP5D RALGPS2	5.85e-04	170	43	3	e421f9eedf74baffda1d03707a710ece4b777f29
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L6_THEMIS_C6orf48\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MGAT5 ITGB8 ZNF804B	5.95e-04	171	43	3	75279ca22f5dd6cfee11c83f3a7b5f828cdec1c6
ToppCell	10x5'-Liver-Myeloid_Mac-Intermediate_macrophages\|Liver / Manually curated celltypes from each tissue	NCF2 ITGB8 CYP27A1	5.95e-04	171	43	3	25e0333743affdb662223fb5220b8a61fa02ad9f
ToppCell	356C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CADM1 DNAH17 CYP27A1	5.95e-04	171	43	3	3d26ef58fe5231373d7df9ac79d225546918cf82
Drug	15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A	ZNF202 SBF1 IL1RAP DNAH17 CEMIP RALGPS2	1.24e-06	194	41	6	7494_UP
Drug	ethyl vinyl ether	ST6GAL1 MGAT3 MGAT5	5.15e-06	19	41	3	CID000008023
Drug	NSC100058	ZNF202 ST6GAL1 MGAT3 MGAT5	9.50e-06	74	41	4	CID000003449
Drug	Cycloheximide [66-81-9]; Down 200; 14.2uM; PC3; HT_HG-U133A	ST6GAL1 MGAT5 ITGA2 IL1RAP CYP27A1	1.79e-05	181	41	5	5743_DN
Drug	B 113	CADM1 ITGA2	1.89e-05	4	41	2	CID000009993
Drug	AC1NRAF5	DPP4 CADM1	1.89e-05	4	41	2	CID005287848
Drug	Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A	DNAH3 ST6GAL1 COLGALT2 HCN4 RALGPS2	2.37e-05	192	41	5	1207_UP
Drug	genistein; Up 200; 10uM; MCF7; HT_HG-U133A	CADM1 ITGA2 OSGIN1 CEMIP RALGPS2	2.55e-05	195	41	5	1660_UP
Drug	Roxarsone [121-19-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A	DPP4 ST6GAL1 HCN4 DNAH17 RALGPS2	2.55e-05	195	41	5	3511_UP
Drug	Tolmetin sodium salt dihydrate [64490-92-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A	ST6GAL1 FASLG HCN4 GRM7 RALGPS2	2.62e-05	196	41	5	4167_UP
Drug	Lidoflazine [3416-26-0]; Up 200; 8.2uM; MCF7; HT_HG-U133A	HCN4 GRM7 SYT11 OSGIN1 CEMIP	2.68e-05	197	41	5	3201_UP
Drug	Cefaclor [70356-03-5]; Down 200; 10.4uM; PC3; HT_HG-U133A	RNF2 IL1RAP SYT11 DNAH17 CYP27A1	2.75e-05	198	41	5	6622_DN
Drug	2-bromopropane	ITGA2 FASLG	4.72e-05	6	41	2	CID000006358
Drug	GABA methylester	ITGA2 FASLG	6.61e-05	7	41	2	CID000018614
Drug	Dequalinium-14	ITGA2 PIGM	1.13e-04	9	41	2	CID000002497
Drug	AC1N21PP	ITGA2 GRM7	1.13e-04	9	41	2	CID004014619
Drug	sodium chloride	DPP4 ST6GAL1 COLGALT2 MGAT3 MGAT5 FASLG PIK3R3 PIGM	1.32e-04	865	41	8	CID000000206
Drug	Dichlorodiphenyl Dichloroethylene	NCF2 CADM1 STXBP1 FASLG CYP27A1	2.01e-04	302	41	5	ctd:D003633
Drug	Dihydroergotamine tartrate [5989-77-5]; Up 200; 3uM; HL60; HG-U133A	MALT1 NCF2 DNAH17 CYP27A1	2.29e-04	167	41	4	1398_UP
Drug	prochlorperazine dimaleate salt; Up 200; 10uM; MCF7; HT_HG-U133A_EA	DNAH3 HCN4 OSGIN1 CEMIP	2.62e-04	173	41	4	995_UP
Drug	Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A	CADM1 SYT11 PIK3R3 RALGPS2	2.74e-04	175	41	4	4436_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	ST6GAL1 STXBP1 SYT11 CYP27A1	2.86e-04	177	41	4	4821_UP
Drug	15d-PGJ2; Up 200; 10uM; PC3; HT_HG-U133A	ITGA2 RNF2 OSGIN1 RALGPS2	3.24e-04	183	41	4	4455_UP
Drug	AC1L4NWK	DPP4 ITGA2	3.27e-04	15	41	2	CID000189017
Drug	LY 294002; Up 200; 10uM; PC3; HT_HG-U133A	ITGA2 GRM7 ITGB8 RALGPS2	3.45e-04	186	41	4	4460_UP
Drug	Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A	DPP4 DNAH3 ITGA2 CEMIP	3.52e-04	187	41	4	1242_UP
Drug	16, 16-dimethylprostaglandin E2 methyl acetate solution; Up 200; 10uM; PC3; HT_HG-U133A	ST6GAL1 COLGALT2 IL1RAP CEMIP	3.59e-04	188	41	4	6562_UP
Drug	CH2Br	ITGA2 INPP5D	3.74e-04	16	41	2	CID000140103
Drug	PNU-0251126 [267429-19-6]; Up 200; 10uM; MCF7; HT_HG-U133A	COLGALT2 GRM7 OSGIN1 RALGPS2	3.89e-04	192	41	4	4711_UP
Drug	2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A	STXBP1 RNF2 SBF1 CEMIP	3.89e-04	192	41	4	1634_UP
Drug	Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A	ITGA2 ITGB8 CEMIP RALGPS2	3.97e-04	193	41	4	4466_UP
Drug	Fluphenazine dihydrochloride [146-56-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A	MALT1 DNAH3 PIK3R3 DNAH17	4.04e-04	194	41	4	3194_DN
Drug	Tribenoside [10310-32-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A	DPP4 MGAT5 FASLG DNAH17	4.04e-04	194	41	4	3507_UP
Drug	Pyrimethamine [58-14-0]; Up 200; 16uM; PC3; HT_HG-U133A	CADM1 SYT11 CEMIP RALGPS2	4.04e-04	194	41	4	4194_UP
Drug	2-propylpentanoic acid; Up 200; 200uM; PC3; HT_HG-U133A	COLGALT2 SBF1 IL1RAP SYT11	4.12e-04	195	41	4	1214_UP
Drug	Azathymine, 6 [932-53-6]; Down 200; 31.4uM; MCF7; HT_HG-U133A	ZNF202 PIK3R3 CEMIP RALGPS2	4.12e-04	195	41	4	4106_DN
Drug	estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A	HCN4 DNAH17 CYP27A1 CEMIP	4.12e-04	195	41	4	5568_UP
Drug	Oleandomycin phosphate [7060-74-4]; Up 200; 5uM; MCF7; HT_HG-U133A	NCF2 MGAT3 SBF1 CYP27A1	4.12e-04	195	41	4	5676_UP
Drug	Acacetin [480-44-4]; Down 200; 14uM; PC3; HT_HG-U133A	RNF2 IL1RAP PIK3R3 CEMIP	4.12e-04	195	41	4	4324_DN
Drug	Prednicarbate [73771-04-7]; Up 200; 8.2uM; MCF7; HT_HG-U133A	MALT1 DNAH17 OSGIN1 CEMIP	4.12e-04	195	41	4	3542_UP
Drug	(S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; PC3; HT_HG-U133A	DNAH3 CADM1 HCN4 GRM7	4.12e-04	195	41	4	3789_UP
Drug	haloperidol; Down 200; 10uM; HL60; HT_HG-U133A	DNAH3 ST6GAL1 SBF1 IL1RAP	4.12e-04	195	41	4	1144_DN
Drug	Telenzepine dihydrochloride [147416-96-4]; Down 200; 9uM; MCF7; HT_HG-U133A	MALT1 DNAH3 STXBP1 PIK3R3	4.20e-04	196	41	4	7419_DN
Drug	Napelline [5008-52-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A	DPP4 ST6GAL1 SYT11 CEMIP	4.20e-04	196	41	4	6824_UP
Drug	Nocodazole [31430-18-9]; Down 200; 13.2uM; MCF7; HT_HG-U133A	DNAH3 RNF2 SBF1 PIK3R3	4.20e-04	196	41	4	2239_DN
Drug	Procyclidine hydrochloride [1508-76-5]; Down 200; 12.4uM; HL60; HT_HG-U133A	DNAH3 MGAT3 IL1RAP GRM7	4.20e-04	196	41	4	2991_DN
Drug	2-propylpentanoic acid; Down 200; 50uM; PC3; HT_HG-U133A	COLGALT2 SBF1 PIK3R3 CEMIP	4.20e-04	196	41	4	4446_DN
Drug	1,4-anthraquinone	ITGA2 FASLG	4.23e-04	17	41	2	CID000069457
Drug	alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A	ZNF202 MGAT3 RNF2 CEMIP	4.29e-04	197	41	4	1635_UP
Drug	Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; PC3; HT_HG-U133A	ST6GAL1 COLGALT2 PIK3R3 CEMIP	4.29e-04	197	41	4	3801_DN
Drug	Rapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A	ZNF202 ST6GAL1 HCN4 GRM7	4.29e-04	197	41	4	6167_DN
Drug	Tinidazole [19387-91-8]; Up 200; 16.2uM; PC3; HT_HG-U133A	CADM1 GRM7 ITGB8 RALGPS2	4.29e-04	197	41	4	3813_UP
Drug	raloxifene hydrochloride; Up 200; 0.1uM; HL60; HG-U133A	DNAH3 GRM7 INPP5D OSGIN1	4.29e-04	197	41	4	388_UP
Drug	Vitamin K2 [11032-49-8]; Down 200; 9uM; PC3; HT_HG-U133A	DPP4 ITGB8 PIK3R3 CEMIP	4.29e-04	197	41	4	3798_DN
Drug	Pirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; HL60; HG-U133A	STXBP1 IL1RAP CYP27A1 OSGIN1	4.29e-04	197	41	4	1388_UP
Drug	3-Acetamidocoumarin [779-30-6]; Up 200; 19.6uM; PC3; HT_HG-U133A	FASLG ITGB8 DNAH17 CEMIP	4.37e-04	198	41	4	4601_UP
Drug	Molindone hydrochloride [15622-65-8]; Up 200; 12.8uM; HL60; HT_HG-U133A	ZNF202 GRM7 ITGB8 CYP27A1	4.37e-04	198	41	4	2917_UP
Drug	Pramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; MCF7; HT_HG-U133A	MGAT3 MGAT5 ITGA2 FASLG	4.37e-04	198	41	4	3894_UP
Drug	Bethanechol chloride [590-63-6]; Up 200; 20.4uM; MCF7; HT_HG-U133A	MALT1 MGAT3 FASLG OSGIN1	4.37e-04	198	41	4	3537_UP
Drug	Vitexin [3681-93-4]; Up 200; 9.2uM; MCF7; HT_HG-U133A	MGAT5 IL1RAP GRM7 CYP27A1	4.37e-04	198	41	4	4413_UP
Drug	Mecamylamine hydrochloride [826-39-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A	MGAT3 RNF2 SBF1 DNAH17	4.37e-04	198	41	4	7023_UP
Drug	Niflumic acid [4394-00-7]; Down 200; 14.2uM; HL60; HT_HG-U133A	DNAH3 STXBP1 SYT11 INPP5D	4.45e-04	199	41	4	2399_DN
Drug	Protoveratrine A [143-57-7]; Up 200; 5uM; PC3; HT_HG-U133A	MGAT5 FASLG HCN4 ITGB8	4.45e-04	199	41	4	6618_UP
Drug	Spiramycin [8025-81-8]; Up 200; 4.8uM; PC3; HT_HG-U133A	MGAT3 HCN4 SYT11 CEMIP	4.45e-04	199	41	4	3762_UP
Drug	MK-886; Down 200; 1uM; MCF7; HG-U133A	DNAH3 ST6GAL1 IL1RAP HCN4	4.45e-04	199	41	4	264_DN
Drug	estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A	MGAT3 ITGA2 RNF2 DNAH17	4.45e-04	199	41	4	1633_UP
Drug	Tobramycin [32986-56-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A	MALT1 SBF1 IL1RAP ERBIN	4.45e-04	199	41	4	2841_DN
Drug	Sulfamerazine [127-79-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A	DPP4 GRM7 DNAH17 OSGIN1	4.54e-04	200	41	4	4740_UP
Drug	haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A	ZNF202 MGAT3 RNF2 SBF1	4.54e-04	200	41	4	6963_UP
Drug	AC1L1A7Z	ITGA2 SDHB	4.75e-04	18	41	2	CID000000874
Drug	aminocyclopentane	ITGA2 GRM7	5.31e-04	19	41	2	CID000002906
Drug	4-carboxy-3-hydroxyphenylglycine	ITGA2 GRM7	5.89e-04	20	41	2	CID000001297
Drug	1,2-dimethylhydrazine dihydrochloride	MGAT3 MGAT5	5.89e-04	20	41	2	CID000009380
Drug	8a beta-indolizidine-1 alpha, 2 alpha, 8 beta-triol	DPP4 MGAT3 MGAT5	6.48e-04	94	41	3	CID000005363
Drug	glycyl-l-prolylalanine	DPP4 ITGA2	6.50e-04	21	41	2	CID000097052
Drug	boronic acids	DPP4 ITGA2	7.14e-04	22	41	2	CID000139619
Drug	cupric chloride	RNF213 DPP4 NCF2 ST6GAL1 FASLG CYP27A1	8.15e-04	623	41	6	ctd:C029892
Drug	coformycin 5'-phosphate	NCF2 CYP27A1	1.08e-03	27	41	2	CID005287911
Drug	5-Azachrysene	DPP4 ITGA2	1.16e-03	28	41	2	CID000344234
Drug	AC1L3UFA	MGAT3 MGAT5	1.16e-03	28	41	2	CID000122350
Drug	phorbol 12-myristate	NCF2 FASLG GRM7 CYP27A1	1.22e-03	261	41	4	CID000107854
Drug	6-fluorotryptophan	ST6GAL1 MGAT3	1.25e-03	29	41	2	CID000094937
Drug	3,4,3',4'-tetrachlorobiphenyl	NLN DNAH3 IL1RAP ITGB8 CYP27A1	1.27e-03	453	41	5	ctd:C028451
Drug	gly-pro	DPP4 NLN ITGA2	1.28e-03	119	41	3	CID000079101
Drug	indene	NLN MGAT3 INPP5D	1.32e-03	120	41	3	CID000007219
Drug	8-Bromo Cyclic Adenosine Monophosphate	NCF2 CADM1 ITGA2 FASLG PIK3R3 CYP27A1	1.41e-03	693	41	6	ctd:D015124
Drug	AC1Q5TX2	DPP4 ST6GAL1	1.52e-03	32	41	2	CID000051716
Drug	BiM4	ITGA2 FASLG GRM7 PIK3R3	1.65e-03	283	41	4	CID000002399
Disease	N-glycan measurement	ST6GAL1 MGAT3 MGAT5	4.35e-06	22	43	3	EFO_0004999
Disease	IgG disialylation measurement	ST6GAL1 MGAT3	2.07e-05	5	43	2	EFO_0008429
Disease	IgG digalactosylation measurement	ST6GAL1 MGAT3	5.78e-05	8	43	2	EFO_0008424
Disease	anemia (phenotype), response to ribavirin	DNAH17 ZNF804B	7.42e-05	9	43	2	EFO_0004272, GO_1901559
Disease	IgG bisecting N-acetyl glucosamine measurement	ST6GAL1 MGAT3	7.42e-05	9	43	2	EFO_0008426
Disease	IgG monogalactosylation measurement	ST6GAL1 MGAT3	7.42e-05	9	43	2	EFO_0008423
Disease	IgG fucosylation measurement	ST6GAL1 MGAT3	9.27e-05	10	43	2	EFO_0008427
Disease	IgG sialylation measurement	ST6GAL1 MGAT3	9.27e-05	10	43	2	EFO_0008428
Disease	serum IgG glycosylation measurement	CWF19L2 ST6GAL1 MGAT3 ALKBH8 SBF1 ZNF804B	1.05e-04	523	43	6	EFO_0005193
Disease	IgG galactosylation measurement	ST6GAL1 MGAT3	1.36e-04	12	43	2	EFO_0008425
Disease	proteinuria (implicated_via_orthology)	NCF2 MGAT5	8.79e-04	30	43	2	DOID:576 (implicated_via_orthology)
Disease	colorectal adenoma	GRM7 INPP5D	1.06e-03	33	43	2	EFO_0005406
Disease	clopidogrel metabolite measurement	RNF2 GRM7	1.06e-03	33	43	2	EFO_0007966
Disease	glucagon measurement	IL1RAP GRM7 ACTR3C	1.48e-03	154	43	3	EFO_0008463
Disease	Moyamoya disease	RNF213 NLN	1.56e-03	40	43	2	MONDO_0016820
Disease	cervix uteri carcinoma in situ (is_marker_for)	CADM1 FASLG	1.72e-03	42	43	2	DOID:8991 (is_marker_for)
Disease	type 2 diabetes mellitus (is_implicated_in)	DPP4 ITGA2 FASLG	1.99e-03	171	43	3	DOID:9352 (is_implicated_in)
Disease	hippocampal CA1 volume	DPP4 MGAT5	2.24e-03	48	43	2	EFO_0009394

Protein segments in the cluster

Peptide	Gene	Start	Entry
PPYKFIHMLKGISIY	SYT11	51	Q9BT88
IDYLMLKVAHQPPYT	ERBIN	1291	Q96RT1
YIKHKPDQMTINQYE	ALKBH8	216	Q96BT7
MKIIKNDFPSHPLYL	CEMIP	1016	Q8WUJ3
IKINPKLHTPMYFFL	OR5D16	51	Q8NGK9
PVQIAVYHMLYKLMP	LTN1	1396	O94822
LSVPMPYTLKVHYKY	NCF2	346	P19878
VHYKYTVVMKTQPGL	NCF2	356	P19878
DPSEHMYAPKYLLKN	MGAT3	476	Q09327
PLTHETKKLYMVPYV	MALT1	266	Q9UDY8
TKKLYMVPYVDLEHQ	MALT1	271	Q9UDY8
VKAILNQKIEPYMPY	MGAT5	591	Q09328
PMKLPVHKLYIEYGI	IL1RAP	141	Q9NPH3
LYKMEQIPLSYPQGH	ACTR3C	186	Q9C0K3
KKQYHMVYECIPLPK	CWF19L2	761	Q2TBE0
HELKPYVIFIKPSNM	MPP4	536	Q96JB8
YQMILPPHFDKSKKY	DPP4	526	P27487
IHIPQYTKEKNPLMY	ITGA2	991	P17301
YKQVEQYMSFHKLPP	HCN4	531	Q9Y3Q4
YKNENPYPAVAMHKV	SBF1	476	O95248
MLKVHPLKKYPVDLY	ITGB8	136	P26012
AQYNPKLDVKLMYPV	PIK3R3	146	Q92569
YKPQVHIQMTYPLQG	CADM1	241	Q9BY67
TKYFNPHYKPEMQAQ	DNAH17	3531	Q9UFH2
YPLLQAMLKNKVPYE	DNAH3	856	Q8TD57
LHQLQVLYKAKYGPM	CYP27A1	81	Q02318
LPVVKKMTFSEHPYN	CDK11A	656	Q9UQ88
YMPKVYIIIFHPELN	GRM7	841	Q14831
MYIYKVLKQVHPDIG	H2BK1	36	A0A2R8Y619
LPVMYNKHPVAEYKE	COLGALT2	526	Q8IYK4
VNKPMELYYAPTKEH	RNF2	321	Q99496
FNQLPKMLYPEYHKV	OSGIN1	326	Q9UJX0
PMLPHVQKYLNSVQY	RALGPS2	251	Q86X27
YKKENMGLVTHLQYP	INPP5D	86	Q92835
KLHPNQPFYILKPQM	ST6GAL1	286	P15907
FYSPHKAQMKNPILE	STXBP1	156	P61764
KNLMKHGYPLIIYDV	HIBADH	56	P31937
ITLKYPHYFPVMKKC	NLN	241	Q9BYT8
YDIVYMKPHGRLQKV	RNF213	496	Q63HN8
LIQEDYQYPKPKTMI	ZNF804B	526	A4D1E1
PMIKFTTKIYHPNVD	UBE2L6	66	O14933
PLSHKVYMRNSKYPQ	FASLG	206	P48023
LNKVSKIYPLPHMYV	SDHB	121	P21912
KIYPLPHMYVIKDLV	SDHB	126	P21912
AVHMKIYPVTYILPI	PIGM	176	Q9H3S5
VHKMNAPYKYPLNRK	ZNF202	446	O95125