Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF66 ZNF7 ZNF816 ZNF624 ZNF16 ZNF880 ZNF766 ZNF799 ZNF749 ZNF470 ZNF221 ZNF860 ZNF302 ZNF160 ZSCAN21 ZNF41 ZIM3 ZNF570 ZNF774 ZNF433 SMAD5 ZNF239 ZNF331	3.52e-16	1412	42	23	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF66 ZNF7 ZNF816 ZNF624 ZNF16 ZNF880 ZNF766 ZNF799 ZNF749 ZNF470 ZNF221 ZNF860 ZNF302 ZNF160 ZSCAN21 ZNF41 ZIM3 ZNF570 ZNF774 ZNF433 SMAD5 ZNF239 ZNF331	7.18e-16	1459	42	23	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF66 ZNF7 ZNF816 ZNF624 ZNF16 ZNF880 ZNF766 ZNF470 ZNF221 ZNF860 ZNF302 ZNF160 ZSCAN21 ZNF41 ZIM3 ZNF570 ZNF774 ZNF433 SMAD5 ZNF239 ZNF331	6.26e-15	1244	42	21	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF66 ZNF7 ZNF816 ZNF624 ZNF16 ZNF880 ZNF766 ZNF470 ZNF221 ZNF860 ZNF302 ZNF160 ZSCAN21 ZNF41 ZIM3 ZNF570 ZNF774 ZNF433 SMAD5 ZNF239 ZNF331	9.58e-15	1271	42	21	GO:0000987
Domain	KRAB	ZNF7 ZNF816 ZNF624 ZNF233 ZNF880 ZNF766 ZNF799 ZNF749 ZNF470 ZNF221 ZNF860 ZNF302 ZNF235 ZNF160 ZNF41 ZIM3 ZNF570 ZNF774 ZNF433 ZNF331	9.24e-24	358	42	20	PS50805
Domain	ZINC_FINGER_C2H2_1	CIZ1 ZNF7 ZNF816 ZNF624 ZNF16 ZNF233 ZNF880 ZNF766 ZNF799 ZNF749 ZNF470 ZNF221 ZNF860 ZNF302 ZNF235 ZNF160 ZSCAN21 ZNF41 ZIM3 ZNF570 ZNF774 ZNF433 ZNF239 ZNF331	8.89e-23	777	42	24	PS00028
Domain	-	ZNF7 ZNF816 ZNF624 ZNF16 ZNF233 ZNF880 ZNF766 ZNF799 ZNF749 ZNF470 ZNF221 ZNF860 ZNF302 ZNF235 ZNF160 ZSCAN21 ZNF41 ZIM3 ZNF570 ZNF774 ZNF433 ZNF239 ZNF331	1.27e-22	679	42	23	3.30.160.60
Domain	Znf_C2H2-like	CIZ1 ZNF7 ZNF816 ZNF624 ZNF16 ZNF233 ZNF880 ZNF766 ZNF799 ZNF749 ZNF470 ZNF221 ZNF860 ZNF302 ZNF235 ZNF160 ZSCAN21 ZNF41 ZIM3 ZNF570 ZNF774 ZNF433 ZNF239 ZNF331	1.57e-22	796	42	24	IPR015880
Domain	zf-C2H2	ZNF7 ZNF816 ZNF624 ZNF16 ZNF233 ZNF880 ZNF766 ZNF799 ZNF749 ZNF470 ZNF221 ZNF860 ZNF302 ZNF235 ZNF160 ZSCAN21 ZNF41 ZIM3 ZNF570 ZNF774 ZNF433 ZNF239 ZNF331	2.01e-22	693	42	23	PF00096
Domain	Znf_C2H2	CIZ1 ZNF7 ZNF816 ZNF624 ZNF16 ZNF233 ZNF880 ZNF766 ZNF799 ZNF749 ZNF470 ZNF221 ZNF860 ZNF302 ZNF235 ZNF160 ZSCAN21 ZNF41 ZIM3 ZNF570 ZNF774 ZNF433 ZNF239 ZNF331	2.05e-22	805	42	24	IPR007087
Domain	Znf_C2H2/integrase_DNA-bd	ZNF7 ZNF816 ZNF624 ZNF16 ZNF233 ZNF880 ZNF766 ZNF799 ZNF749 ZNF470 ZNF221 ZNF860 ZNF302 ZNF235 ZNF160 ZSCAN21 ZNF41 ZIM3 ZNF570 ZNF774 ZNF433 ZNF239 ZNF331	2.08e-22	694	42	23	IPR013087
Domain	ZnF_C2H2	CIZ1 ZNF7 ZNF816 ZNF624 ZNF16 ZNF233 ZNF880 ZNF766 ZNF799 ZNF749 ZNF470 ZNF221 ZNF860 ZNF302 ZNF235 ZNF160 ZSCAN21 ZNF41 ZIM3 ZNF570 ZNF774 ZNF433 ZNF239 ZNF331	2.24e-22	808	42	24	SM00355
Domain	KRAB	ZNF7 ZNF816 ZNF624 ZNF233 ZNF880 ZNF766 ZNF799 ZNF749 ZNF470 ZNF221 ZNF860 ZNF302 ZNF235 ZNF160 ZNF41 ZIM3 ZNF570 ZNF433 ZNF331	4.34e-22	358	42	19	PF01352
Domain	KRAB	ZNF7 ZNF816 ZNF624 ZNF233 ZNF880 ZNF766 ZNF799 ZNF749 ZNF470 ZNF221 ZNF860 ZNF302 ZNF235 ZNF160 ZNF41 ZIM3 ZNF570 ZNF433 ZNF331	7.73e-22	369	42	19	SM00349
Domain	KRAB	ZNF7 ZNF816 ZNF624 ZNF233 ZNF880 ZNF766 ZNF799 ZNF749 ZNF470 ZNF221 ZNF860 ZNF302 ZNF235 ZNF160 ZNF41 ZIM3 ZNF570 ZNF433 ZNF331	8.14e-22	370	42	19	IPR001909
Domain	ZINC_FINGER_C2H2_2	ZNF7 ZNF816 ZNF624 ZNF16 ZNF233 ZNF880 ZNF766 ZNF799 ZNF749 ZNF470 ZNF221 ZNF860 ZNF302 ZNF235 ZNF160 ZSCAN21 ZNF41 ZIM3 ZNF570 ZNF774 ZNF433 ZNF239 ZNF331	2.52e-21	775	42	23	PS50157
Domain	zf-C2H2_6	ZNF816 ZNF624 ZNF16 ZNF880 ZNF766 ZNF799 ZNF749 ZNF860 ZNF302 ZNF160 ZIM3 ZNF570 ZNF433 ZNF331	3.74e-15	314	42	14	PF13912
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF624 ZNF233 ZNF799 ZNF749 ZNF470 ZNF221 ZNF860 ZNF302 ZNF235 ZNF160 ZNF41 ZIM3 ZNF570 ZNF774 ZNF433 ZNF331	1.63e-08	1387	33	16	M734
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF7 ZNF624 ZNF766 ZNF799 ZNF749 ZNF235 ZNF160 ZNF41	5.72e-11	181	43	8	37372979
Pubmed	Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.	ZNF233 ZNF221 ZNF235	1.98e-06	20	43	3	12743021
Pubmed	Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937.	ZNF302 ZNF235 ZNF160	2.31e-06	21	43	3	7865130
Pubmed	Coding region intron/exon organization, alternative splicing, and X-chromosome inactivation of the KRAB/FPB-domain-containing human zinc finger gene ZNF41.	ZNF221 ZNF41	4.48e-06	3	43	2	10449920
Pubmed	Chromosomal localization of two KOX zinc finger genes on chromosome bands 7q21-q22.	ZNF16 ZSCAN21	8.94e-06	4	43	2	7486829
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF7 ZNF624 ZNF160	3.12e-05	49	43	3	9630514
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	CIZ1 ZNF7 KDM4A ZNF235 ZNF160 ZSCAN21 ZNF239	5.54e-05	808	43	7	20412781
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	ZNF880 ZNF766 ZNF749 ZNF235 ZSCAN21	2.30e-04	451	43	5	36168627
Pubmed	Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.	ZNF7 ZNF624	2.80e-04	20	43	2	2542606
Pubmed	Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.	ZNF7 ZNF624	2.80e-04	20	43	2	7479878
Pubmed	Characterization and mapping of human genes encoding zinc finger proteins.	ZNF66 ZNF7	3.40e-04	22	43	2	1946370
Pubmed	Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.	ZNF302 ZNF235 GTF3C3	4.05e-04	116	43	3	21549307
Pubmed	The DNA sequence and biology of human chromosome 19.	ZNF749 ZNF470 ZNF221 ZNF239	4.18e-04	284	43	4	15057824
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF7 ZNF16	6.79e-04	31	43	2	2288909
Pubmed	SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.	ZNF66 ZNF16 ZNF766 ZNF470 ZNF221 ASIC4	8.67e-04	915	43	6	32393512
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	CIZ1 KDM4A ZSCAN21 ZNF570 GTF3C3	8.93e-04	608	43	5	36089195
Interaction	LTBP2 interactions	ZNF624 ZNF766 ZNF749 ZSCAN21	2.92e-05	85	42	4	int:LTBP2
Interaction	LRP1B interactions	HRG ZSCAN21 EGFL6 ZNF331	2.92e-05	85	42	4	int:LRP1B
Interaction	TRIM28 interactions	ZNF7 ZNF816 ZNF624 ZNF766 ZNF799 ZNF749 ZNF302 ZNF235 ZNF160 PMPCB ZNF41 ZNF331	3.14e-05	1474	42	12	int:TRIM28
Interaction	KRTAP10-6 interactions	ZNF221 ZNF302 ZNF774 ZNF239	3.35e-05	88	42	4	int:KRTAP10-6
Interaction	SORL1 interactions	ZNF816 ZSCAN21 EGFL6 ZNF331	1.93e-04	138	42	4	int:SORL1
Interaction	CEP70 interactions	ZNF860 ZNF302 ZSCAN21 ZNF433 ZNF239	2.05e-04	262	42	5	int:CEP70
Interaction	ANOS1 interactions	ZNF7 ZNF624 ZNF16 ZSCAN21	2.21e-04	143	42	4	int:ANOS1
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF816 ZNF233 ZNF880 ZNF766 ZNF749 ZNF470 ZNF221 ZNF302 ZNF235 ZNF160 ZIM3 ZNF570 ZNF331	4.06e-11	1192	43	13	chr19q13
Cytoband	19q13.41	ZNF816 ZNF880 ZNF766	5.54e-05	78	43	3	19q13.41
Cytoband	8q24	ZNF7 ZNF16	3.19e-04	28	43	2	8q24
Cytoband	19q13.43	ZNF749 ZNF470	3.05e-03	87	43	2	19q13.43
Cytoband	7q22.1	ZSCAN21 PMPCB	5.08e-03	113	43	2	7q22.1
Cytoband	19q13.42	ZNF160 ZNF331	6.17e-03	125	43	2	19q13.42
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF7 ZNF816 ZNF624 ZNF16 ZNF233 ZNF880 ZNF766 ZNF799 ZNF749 ZNF470 ZNF221 ZNF860 ZNF302 ZNF235 ZNF160 ZSCAN21 ZNF41 ZIM3 ZNF570 ZNF774 ZNF433 ZNF239 ZNF331	8.75e-23	718	39	23	28
Coexpression	GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_UP	ZNF624 ZSCAN21 ZNF570 SMAD5 ZNF331	1.59e-05	198	42	5	M4291
ToppCell	TCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Seminoma-_NOS-5\|TCGA-Testes / Sample_Type by Project: Shred V9	ZNF233 ZNF766 ZNF235 PXDNL ZNF331	5.05e-07	163	43	5	80bc3732afd8501938753120b8403098c7c5e928
ToppCell	TCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Seminoma-_NOS\|TCGA-Testes / Sample_Type by Project: Shred V9	ZNF233 ZNF766 ZNF235 PXDNL ZNF331	5.05e-07	163	43	5	67551fefe22bd5b8178fa248fed2a6c17b19fb0f
Disease	partial thromboplastin time	HRG ZNF160	4.38e-04	24	38	2	EFO_0004310
Disease	venous thromboembolism, von Willebrand factor measurement	CLEC4M ZNF160	1.35e-03	42	38	2	EFO_0004286, EFO_0004629
Disease	cognitive inhibition measurement	USH2A PXDNL	1.90e-03	50	38	2	EFO_0007969
Disease	liver cirrhosis (is_marker_for)	ITGB6 CD163	5.03e-03	82	38	2	DOID:5082 (is_marker_for)
Disease	Abortion, Tubal	ITGB6 CD163	8.72e-03	109	38	2	C0000822
Disease	Early Pregnancy Loss	ITGB6 CD163	8.72e-03	109	38	2	C3830362
Disease	Miscarriage	ITGB6 CD163	8.72e-03	109	38	2	C4552766
Disease	Spontaneous abortion	ITGB6 CD163	8.72e-03	109	38	2	C0000786
Disease	lipoprotein A measurement	CLEC4M PMPCB	9.18e-03	112	38	2	EFO_0006925
Disease	von Willebrand factor measurement, coronary artery disease	CLEC4M PMPCB	1.01e-02	118	38	2	EFO_0001645, EFO_0004629

Protein segments in the cluster

Peptide	Gene	Start	Entry
FQNAGHSFKKQHICS	nan	51	Q0VG73
SGCGYSIHQHQGNKQ	ASAP3	286	Q8TDY4
SHHANCFNTQGSFKC	EGFL6	231	Q8IUX8
SKIHGNFTHGNFTQD	ADGRG4	2351	Q8IZF6
HNCTGNSSQHFFRQG	AKAP11	1596	Q9UKA4
TCHGNLCHSFQSFNT	PMPCB	341	O75439
SCQHATFGTNGAQRH	HRG	326	P04196
HPQLCFKFSFGNSSH	IL17RE	336	Q8NFR9
EVNSSKCHHGNGSFQ	ITGB6	461	P18564
HAGFNHGFNCAESTN	KDM4A	276	O75164
NFSGHHCSASNFSVV	ASIC4	181	Q96FT7
QGFAQHGHTQAAATC	PXDNL	196	A1KZ92
FTCHANNSHGTVQAA	PXDNL	396	A1KZ92
QGFFFSSCHPQNHVS	KRTAP25-1	6	Q3LHN0
GKHSNCTHQQDAGVT	CD163	136	Q86VB7
LHGSVNKFCNPHSGQ	USH2A	751	O75445
EQSFHANNGHASSSC	SLC41A2	91	Q96JW4
SSIFVQSRNCNFHHG	SMAD5	351	Q99717
HNAFVSGSFKHALGQ	GTF3C3	741	Q9Y5Q9
FQFQQIHGHKSSTGC	CLEC4M	31	Q9H2X3
NSGAQLSHCKSLGHF	CIZ1	811	Q9ULV3
CGKVFTSNSGFNTHQ	ZNF624	701	Q9P2J8
CGKAFFQKSNLHSHQ	ZIM3	396	Q96PE6
HECGKVFTQNSHLAN	ZNF880	271	Q6PDB4
QCGKVFTQNSHLANH	ZNF160	681	Q9HCG1
FNSSQGGKDFCHQHG	ZNF749	196	O43361
CGKAFNHSSNFNKHH	ZSCAN21	421	Q9Y5A6
CGKTFNQRSHFLTHQ	ZNF774	436	Q6NX45
CGKSFSHGHQLTQHQ	ZNF331	416	Q9NQX6
CQQCGKAFHHLGSFQ	ZNF799	311	Q96GE5
CGKAFSQSAHLAQHQ	ZNF470	261	Q6ECI4
CGKAFIQKSHFNTHQ	ZNF41	486	P51814
CGKEFNQSSHLQTHQ	ZNF221	231	Q9UK13
CGKAFSQNSHLAQHQ	ZNF570	391	Q96NI8
CGKGFSQSSHLQDHQ	ZNF233	541	A6NK53
CGKGFSQSSHLIQHQ	ZNF16	606	P17020
QCDKHGKVFHQFSNT	ZNF66	146	Q6ZN08
CGKVFNQQSNLASHH	ZNF860	291	A6NHJ4
CGKVFTQNSHLANHQ	ZNF766	416	Q5HY98
ECGKGFSQSSNLHIH	ZNF239	351	Q16600
CGKGFSQSSNLHIHQ	ZNF239	436	Q16600
QCGKAFSSSHSFQIH	ZNF433	286	Q8N7K0
QQCGKGFSQASHFHT	ZNF235	686	Q14590
CGKAFTGQSTLIHHQ	ZNF816	626	Q0VGE8
CGKAFGQSSSLIHHQ	ZNF7	311	P17097
CGKAFSHGSSLTNHQ	ZNF302	341	Q9NR11