Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranslation activator activity

DAZ4 DAZ1 DAZ3 DAZ2

8.54e-0815584GO:0008494
GeneOntologyMolecularFunctiontranslation regulator activity, nucleic acid binding

DAZ4 DAZ1 DAZ3 DAZ2

3.15e-04112584GO:0090079
GeneOntologyMolecularFunction3'-phosphoadenosine 5'-phosphosulfate binding

ENPP1 SULT1C3

6.34e-0413582GO:0050656
GeneOntologyMolecularFunctionpyrophosphatase activity

ARHGAP5 RRAGA ENPP1 RNF213 GNA12 SLFN11 AQR RAD54L

2.80e-03839588GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ARHGAP5 RRAGA ENPP1 RNF213 GNA12 SLFN11 AQR RAD54L

2.82e-03840588GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ARHGAP5 RRAGA ENPP1 RNF213 GNA12 SLFN11 AQR RAD54L

2.82e-03840588GO:0016818
GeneOntologyBiologicalProcessfemale meiosis II

DAZ4 DAZ1 DAZ3 DAZ2

8.41e-106584GO:0007147
GeneOntologyBiologicalProcessmeiosis II

DAZ4 DAZ1 DAZ3 DAZ2

8.41e-106584GO:0007135
GeneOntologyBiologicalProcessmeiosis II cell cycle process

DAZ4 DAZ1 DAZ3 DAZ2

8.41e-106584GO:0061983
GeneOntologyBiologicalProcesspositive regulation of meiotic nuclear division

DAZ4 DAZ1 DAZ3 DAZ2

8.03e-0726584GO:0045836
GeneOntologyBiologicalProcesspositive regulation of translational initiation

DAZ4 DAZ1 DAZ3 DAZ2

1.27e-0629584GO:0045948
GeneOntologyBiologicalProcess3'-UTR-mediated mRNA stabilization

DAZ4 DAZ1 DAZ3 DAZ2

1.67e-0631584GO:0070935
GeneOntologyBiologicalProcesspositive regulation of meiotic cell cycle

DAZ4 DAZ1 DAZ3 DAZ2

3.47e-0637584GO:0051446
GeneOntologyBiologicalProcessregulation of meiotic nuclear division

DAZ4 DAZ1 DAZ3 DAZ2

7.69e-0645584GO:0040020
GeneOntologyBiologicalProcessoocyte maturation

DAZ4 DAZ1 DAZ3 DAZ2

9.17e-0647584GO:0001556
GeneOntologyBiologicalProcessfemale meiotic nuclear division

DAZ4 DAZ1 DAZ3 DAZ2

1.38e-0552584GO:0007143
GeneOntologyBiologicalProcesspositive regulation of nuclear division

DAZ4 DAZ1 DAZ3 DAZ2

5.90e-0575584GO:0051785
GeneOntologyBiologicalProcessmRNA stabilization

DAZ4 DAZ1 DAZ3 DAZ2

6.54e-0577584GO:0048255
GeneOntologyBiologicalProcessregulation of meiotic cell cycle

DAZ4 DAZ1 DAZ3 DAZ2

8.36e-0582584GO:0051445
GeneOntologyBiologicalProcessnegative regulation of mRNA catabolic process

DAZ4 DAZ1 DAZ3 DAZ2

1.05e-0487584GO:1902373
GeneOntologyBiologicalProcessRNA stabilization

DAZ4 DAZ1 DAZ3 DAZ2

1.10e-0488584GO:0043489
GeneOntologyBiologicalProcessregulation of translational initiation

DAZ4 DAZ1 DAZ3 DAZ2

1.25e-0491584GO:0006446
GeneOntologyBiologicalProcessplatelet-derived growth factor receptor-alpha signaling pathway

PDGFRA CBLB

1.62e-047582GO:0035790
GeneOntologyBiologicalProcessoocyte development

DAZ4 DAZ1 DAZ3 DAZ2

1.74e-0499584GO:0048599
GeneOntologyBiologicalProcessnegative regulation of RNA catabolic process

DAZ4 DAZ1 DAZ3 DAZ2

1.88e-04101584GO:1902369
GeneOntologyBiologicalProcessoocyte differentiation

DAZ4 DAZ1 DAZ3 DAZ2

2.02e-04103584GO:0009994
GeneOntologyBiologicalProcessnucleotide-sugar metabolic process

GNE FUT8 CSGALNACT1

2.57e-0444583GO:0009225
GeneOntologyBiologicalProcessnegative regulation of mRNA metabolic process

DAZ4 DAZ1 DAZ3 DAZ2

3.08e-04115584GO:1903312
GeneOntologyBiologicalProcessnuclear membrane organization

BROX ANKLE2 CTDNEP1

3.34e-0448583GO:0071763
GeneOntologyBiologicalProcesspositive regulation of reproductive process

DAZ4 DAZ1 DAZ3 DAZ2

3.40e-04118584GO:2000243
GeneOntologyBiologicalProcessmitotic nuclear membrane organization

BROX ANKLE2

3.45e-0410582GO:0101024
GeneOntologyBiologicalProcessmitotic nuclear membrane reassembly

BROX ANKLE2

3.45e-0410582GO:0007084
GeneOntologyBiologicalProcessmeiotic cell cycle

ZFP42 DAZ4 DAZ1 DAZ3 DAZ2 RAD54L

4.40e-04350586GO:0051321
GeneOntologyBiologicalProcessanatomical structure maturation

ENPP1 DAZ4 DAZ1 DAZ3 DAZ2 FARP2

4.68e-04354586GO:0071695
GeneOntologyBiologicalProcesstranslational initiation

DAZ4 DAZ1 DAZ3 DAZ2

5.20e-04132584GO:0006413
GeneOntologyBiologicalProcessnuclear division

BROX DAZ4 DAZ1 DAZ3 DAZ2 ANKLE2 RAD54L

5.61e-04512587GO:0000280
GeneOntologyBiologicalProcessmeiotic nuclear division

DAZ4 DAZ1 DAZ3 DAZ2 RAD54L

5.67e-04240585GO:0140013
GeneOntologyBiologicalProcessnuclear envelope organization

BROX ANKLE2 CTDNEP1

7.43e-0463583GO:0006998
GeneOntologyBiologicalProcesspositive regulation of translation

DAZ4 DAZ1 DAZ3 DAZ2

8.61e-04151584GO:0045727
GeneOntologyBiologicalProcesscell maturation

DAZ4 DAZ1 DAZ3 DAZ2 FARP2

9.17e-04267585GO:0048469
GeneOntologyBiologicalProcessmeiotic cell cycle process

DAZ4 DAZ1 DAZ3 DAZ2 RAD54L

9.32e-04268585GO:1903046
GeneOntologyBiologicalProcessoogenesis

DAZ4 DAZ1 DAZ3 DAZ2

9.72e-04156584GO:0048477
GeneOntologyBiologicalProcesspurine ribonucleoside bisphosphate metabolic process

ENPP1 SULT1C3

1.03e-0317582GO:0034035
GeneOntologyBiologicalProcess3'-phosphoadenosine 5'-phosphosulfate metabolic process

ENPP1 SULT1C3

1.03e-0317582GO:0050427
GeneOntologyBiologicalProcessorganelle fission

BROX DAZ4 DAZ1 DAZ3 DAZ2 ANKLE2 RAD54L

1.06e-03571587GO:0048285
MousePhenoabsent ovarian follicles

DAZ4 DAZ1 DAZ3 DAZ2

1.44e-0551414MP:0002777
DomainFERM_N

TLN2 FRMD1 FARP2

1.31e-0433563PF09379
DomainFERM_N

TLN2 FRMD1 FARP2

1.31e-0433563IPR018979
DomainFERM_M

TLN2 FRMD1 FARP2

3.54e-0446563PF00373
Domain-

TLN2 FRMD1 FARP2

4.27e-04495631.20.80.10
DomainFERM_central

TLN2 FRMD1 FARP2

4.27e-0449563IPR019748
DomainFERM_domain

TLN2 FRMD1 FARP2

4.27e-0449563IPR000299
DomainFERM_1

TLN2 FRMD1 FARP2

4.53e-0450563PS00660
DomainFERM_2

TLN2 FRMD1 FARP2

4.53e-0450563PS00661
DomainFERM_3

TLN2 FRMD1 FARP2

4.53e-0450563PS50057
DomainBand_41_domain

TLN2 FRMD1 FARP2

4.53e-0450563IPR019749
DomainB41

TLN2 FRMD1 FARP2

4.53e-0450563SM00295
DomainFERM/acyl-CoA-bd_prot_3-hlx

TLN2 FRMD1 FARP2

4.53e-0450563IPR014352
Domain-

ARHGAP5 RRAGA SULT1C3 RNF213 GNA12 SLFN11 AQR RAD54L

1.62e-037465683.40.50.300
DomainPH_dom-like

ARHGEF19 SH3BP2 SPTBN2 TLN2 FRMD1 FARP2

1.68e-03426566IPR011993
DomainFERM_CS

TLN2 FARP2

2.34e-0324562IPR019747
DomainFERM_C

FRMD1 FARP2

2.95e-0327562SM01196
DomainFERM_PH-like_C

FRMD1 FARP2

2.95e-0327562IPR018980
DomainRRM_1

DAZ4 DAZ1 DAZ3 DAZ2

3.49e-03208564PF00076
DomainP-loop_NTPase

ARHGAP5 RRAGA SULT1C3 RNF213 GNA12 SLFN11 AQR RAD54L

3.59e-03848568IPR027417
Domain-

ZFP42 IKZF3 ZBTB48 ZNF740 ZNF721 ZNF30 ZFP62

4.02e-036795673.30.160.60
DomainRRM

DAZ4 DAZ1 DAZ3 DAZ2

4.06e-03217564SM00360
DomainZnf_C2H2/integrase_DNA-bd

ZFP42 IKZF3 ZBTB48 ZNF740 ZNF721 ZNF30 ZFP62

4.52e-03694567IPR013087
DomainRRM_dom

DAZ4 DAZ1 DAZ3 DAZ2

4.76e-03227564IPR000504
DomainRRM

DAZ4 DAZ1 DAZ3 DAZ2

4.99e-03230564PS50102
DomainDeath_domain

ANKDD1B IRAK2

5.79e-0338562IPR000488
DomainDEATH_DOMAIN

ANKDD1B IRAK2

5.79e-0338562PS50017
Domain-

DAZ4 DAZ1 DAZ3 DAZ2

6.13e-032445643.30.70.330
Domain-

ARHGEF19 SH3BP2 SPTBN2 TLN2 FARP2

6.24e-033915652.30.29.30
DomainNucleotide-bd_a/b_plait

DAZ4 DAZ1 DAZ3 DAZ2

7.45e-03258564IPR012677
DomainZINC_FINGER_C2H2_2

ZFP42 IKZF3 ZBTB48 ZNF740 ZNF721 ZNF30 ZFP62

8.16e-03775567PS50157
DomainZINC_FINGER_C2H2_1

ZFP42 IKZF3 ZBTB48 ZNF740 ZNF721 ZNF30 ZFP62

8.27e-03777567PS00028
DomainZnf_C2H2-like

ZFP42 IKZF3 ZBTB48 ZNF740 ZNF721 ZNF30 ZFP62

9.38e-03796567IPR015880
DomainPH

ARHGEF19 SH3BP2 SPTBN2 FARP2

9.62e-03278564SM00233
DomainPH_DOMAIN

ARHGEF19 SH3BP2 SPTBN2 FARP2

9.74e-03279564PS50003
DomainPH_domain

ARHGEF19 SH3BP2 SPTBN2 FARP2

9.86e-03280564IPR001849
PathwayWP_OVARIAN_INFERTILITY

DAZ4 DAZ1 DAZ3 DAZ2

4.82e-0635464MM15948
PathwayWP_MALE_INFERTILITY

DAZ4 DAZ1 XPC DAZ3 DAZ2

1.05e-04145465M39856
Pubmed

Analysis of the DAZ gene family in cryptorchidism and idiopathic male infertility.

DAZ4 DAZ1 DAZ3 DAZ2

6.96e-12458415066457
Pubmed

Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene.

DAZ4 DAZ1 DAZ3 DAZ2

6.96e-1245847670487
Pubmed

Impact of partial DAZ1/2 deletion and partial DAZ3/4 deletion on male infertility.

DAZ4 DAZ1 DAZ3 DAZ2

6.96e-12458426232607
Pubmed

Male infertility, genetic analysis of the DAZ genes on the human Y chromosome and genetic analysis of DNA repair.

DAZ4 DAZ1 DAZ3 DAZ2

6.96e-12458411694340
Pubmed

The human DAZ genes, a putative male infertility factor on the Y chromosome, are highly polymorphic in the DAZ repeat regions.

DAZ4 DAZ1 DAZ3 DAZ2

6.96e-1245849321470
Pubmed

Polymorphic expression of DAZ proteins in the human testis.

DAZ4 DAZ1 DAZ3 DAZ2

6.96e-12458419223287
Pubmed

Male infertility caused by a de novo partial deletion of the DAZ cluster on the Y chromosome.

DAZ4 DAZ1 DAZ3 DAZ2

6.96e-12458411095434
Pubmed

[Microdeletion of chromosome Y in male infertility: role of the DAZ gene].

DAZ4 DAZ1 DAZ3 DAZ2

6.96e-12458411688365
Pubmed

Polymorphic DAZ gene family in polymorphic structure of AZFc locus: Artwork or functional for human spermatogenesis?

DAZ4 DAZ1 DAZ3 DAZ2

6.96e-12458412752250
Pubmed

A novel approach for the analysis of DAZ gene copy number in severely idiopathic infertile men.

DAZ4 DAZ1 DAZ3 DAZ2

6.96e-12458411883873
Pubmed

Four DAZ genes in two clusters found in the AZFc region of the human Y chromosome.

DAZ4 DAZ1 DAZ3 DAZ2

6.96e-12458410936047
Pubmed

[Study on DAZ gene copy deletion in severe oligozoospermia sperm donor for ICSI].

DAZ4 DAZ1 DAZ3 DAZ2

6.96e-12458416963411
Pubmed

Partial DAZ deletions in a family with five infertile brothers.

DAZ4 DAZ1 DAZ3 DAZ2

6.96e-12458412801575
Pubmed

Targets and dynamics of promoter DNA methylation during early mouse development.

ZFP42 DAZ4 DAZ1 DAZ3 DAZ2

2.14e-111458521057502
Pubmed

Mouse Dazl and its novel splice variant functions in translational repression of target mRNAs in embryonic stem cells.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558423298641
Pubmed

Connecting cis-elements and trans-factors with mechanisms of developmental regulation of mRNA translation in meiotic and haploid mammalian spermatogenic cells.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558423579190
Pubmed

DAZL is essential for stress granule formation implicated in germ cell survival upon heat stress.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558422223682
Pubmed

Kinked β-strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZL.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558422021443
Pubmed

The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-1155849288969
Pubmed

The dazzle in germ cell differentiation.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558420008336
Pubmed

Co-culture of spermatogonial stem cells with sertoli cells in the presence of testosterone and FSH improved differentiation via up-regulation of post meiotic genes.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558423456578
Pubmed

Isolation of a mouse homolog of the human DAZ (Deleted in Azoospermia) gene.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-1155848679003
Pubmed

A human DAZ transgene confers partial rescue of the mouse Dazl null phenotype.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558410393944
Pubmed

The human autosomal gene DAZLA: testis specificity and a candidate for male infertility.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-1155848968756
Pubmed

A SPGY copy homologous to the mouse gene Dazla and the Drosophila gene boule is autosomal and expressed only in the human male gonad.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-1155848968755
Pubmed

DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558430380414
Pubmed

Regulated Formation of an Amyloid-like Translational Repressor Governs Gametogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558426411291
Pubmed

In vivo and in vitro analysis of homodimerisation activity of the mouse Dazl1 protein.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558410903443
Pubmed

Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558423223451
Pubmed

Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558434985827
Pubmed

Identification of target messenger RNA substrates for the murine deleted in azoospermia-like RNA-binding protein.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558411804965
Pubmed

Gene sequence, localization, and evolutionary conservation of DAZLA, a candidate male sterility gene.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-1155849143498
Pubmed

Expression profiling of the developing testis in wild-type and Dazl knockout mice.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558414648873
Pubmed

Bisphenol A exposure modifies DNA methylation of imprint genes in mouse fetal germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558422699882
Pubmed

A murine homologue of the human DAZ gene is autosomal and expressed only in male and female gonads.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-1155848845845
Pubmed

The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-1155848896558
Pubmed

DAZ family proteins exist throughout male germ cell development and transit from nucleus to cytoplasm at meiosis in humans and mice.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558411058556
Pubmed

AZFc partial deletions in Chilean men with severe spermatogenic failure.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558417416365
Pubmed

Dazl promotes germ cell differentiation from embryonic stem cells.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558419783541
Pubmed

Retinoic acid regulates germ cell differentiation in mouse embryonic stem cells through a Smad-dependent pathway.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558422293198
Pubmed

DAZL protein expression in mouse preimplantation embryo.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558417761180
Pubmed

Dazl functions in maintenance of pluripotency and genetic and epigenetic programs of differentiation in mouse primordial germ cells in vivo and in vitro.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558419468308
Pubmed

Evolution of the DAZ gene family suggests that Y-linked DAZ plays little, or a limited, role in spermatogenesis but underlines a recent African origin for human populations.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-1155849700189
Pubmed

Partial rescue of the Dazl knockout mouse by the human DAZL gene.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558412200456
Pubmed

Nature of the spermatogenic arrest in Dazl -/- mice.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558411514340
Pubmed

Decreased oocyte DAZL expression in mice results in increased litter size by modulating follicle-stimulating hormone-induced follicular growth.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558421270429
Pubmed

Loss of oocytes in Dazl knockout mice results in maintained ovarian steroidogenic function but altered gonadotropin secretion in adult animals.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-11558411089564
Pubmed

Mouse autosomal homolog of DAZ, a candidate male sterility gene in humans, is expressed in male germ cells before and after puberty.

DAZ4 DAZ1 DAZ3 DAZ2

3.48e-1155848661148
Pubmed

The RNA-binding protein DAZL functions as repressor and activator of mRNA translation during oocyte maturation.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658432170089
Pubmed

Expression profiles of the DAZ gene family in human testis with and without spermatogenic failure.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658415066460
Pubmed

Dazl binds in vivo to specific transcripts and can regulate the pre-meiotic translation of Mvh in germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658416278232
Pubmed

Aged mouse ovaries possess rare premeiotic germ cells that can generate oocytes following transplantation into a young host environment.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658420157580
Pubmed

DAZL binds to the transcripts of several Tssk genes in germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658418452650
Pubmed

A gene trap mutation of a murine homolog of the Drosophila stem cell factor Pumilio results in smaller testes but does not affect litter size or fertility.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658417219433
Pubmed

Mono-butyl phthalate-induced mouse testis injury is associated with oxidative stress and down-regulated expression of Sox9 and Dazl.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658428496037
Pubmed

DAZL regulates Tet1 translation in murine embryonic stem cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658426077710
Pubmed

The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658416001084
Pubmed

Cracd Marks the First Wave of Meiosis during Spermatogenesis and Is Mis-Expressed in Azoospermia Mice.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658432962040
Pubmed

Translation of the synaptonemal complex component Sycp3 is enhanced in vivo by the germ cell specific regulator Dazl.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658417526644
Pubmed

Genetic mapping of a male germ cell-expressed gene Tpx-2 to mouse chromosome 17.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-1065841869307
Pubmed

A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658411390979
Pubmed

A developmental stage-specific switch from DAZL to BOLL occurs during fetal oogenesis in humans, but not mice.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658424086306
Pubmed

BOULE, a Deleted in Azoospermia Homolog, Is Recruited to Stress Granules in the Mouse Male Germ Cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658427632217
Pubmed

The mouse male germ cell-specific gene Tpx-1: molecular structure, mode of expression in spermatogenesis, and sequence similarity to two non-mammalian genes.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-1065841638086
Pubmed

Spermatogenesis in testes of Dazl null mice after transplantation of wild-type germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658414611632
Pubmed

DAZL binds to 3'UTR of Tex19.1 mRNAs and regulates Tex19.1 expression.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658419247806
Pubmed

DAZL is a master translational regulator of murine spermatogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658431355046
Pubmed

The fate of granulosa cells following premature oocyte loss and the development of ovarian cancers.

DAZ4 DAZ1 DAZ3 DAZ2

1.04e-10658423417416
Pubmed

The RNA-binding specificity of the mouse Dazl protein.

DAZ4 DAZ1 DAZ3 DAZ2

2.43e-10758411410654
Pubmed

Identification of a novel gene, DZIP (DAZ-interacting protein), that encodes a protein that interacts with DAZ (deleted in azoospermia) and is expressed in embryonic stem cells and germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

2.43e-10758415081113
Pubmed

Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal mice.

DAZ4 DAZ1 DAZ3 DAZ2

2.43e-10758422699423
Pubmed

Characterization of the mouse Dazap1 gene encoding an RNA-binding protein that interacts with infertility factors DAZ and DAZL.

DAZ4 DAZ1 DAZ3 DAZ2

2.43e-10758411604102
Pubmed

Identification of two novel proteins that interact with germ-cell-specific RNA-binding proteins DAZ and DAZL1.

DAZ4 DAZ1 DAZ3 DAZ2

2.43e-10758410857750
Pubmed

The Dazh gene is expressed in male and female embryonic gonads before germ cell sex differentiation.

DAZ4 DAZ1 DAZ3 DAZ2

2.43e-1075849588208
Pubmed

DAZL and CPEB1 regulate mRNA translation synergistically during oocyte maturation.

DAZ4 DAZ1 DAZ3 DAZ2

2.43e-10758426826184
Pubmed

Dazl can bind to dynein motor complex and may play a role in transport of specific mRNAs.

DAZ4 DAZ1 DAZ3 DAZ2

2.43e-10758416946704
Pubmed

Fanconi anemia complementation group C is required for proliferation of murine primordial germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

4.85e-10858410951504
Pubmed

Single-cell transcriptomics reveal temporal dynamics of critical regulators of germ cell fate during mouse sex determination.

DAZ4 DAZ1 DAZ3 DAZ2

4.85e-10858433749946
Pubmed

Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.

DAZ4 DAZ1 DAZ3 DAZ2

4.85e-10858423204224
Pubmed

Requirement of the 3'-UTR-dependent suppression of DAZL in oocytes for pre-implantation mouse development.

DAZ4 DAZ1 DAZ3 DAZ2

4.85e-10858429883445
Pubmed

Mouse dead end1 acts with Nanos2 and Nanos3 to regulate testicular teratoma incidence.

DAZ4 DAZ1 DAZ3 DAZ2

4.85e-10858432339196
Pubmed

A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection.

DAZ4 DAZ1 DAZ3 DAZ2

4.85e-10858410823932
Pubmed

Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.

DAZ4 DAZ1 DAZ3 DAZ2

4.85e-10858422621333
Pubmed

DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors.

DAZ4 DAZ1 DAZ3 DAZ2

4.85e-10858432686646
Pubmed

A preliminary report on the implication of RT-PCR detection of DAZ, RBMY1, USP9Y and Protamine-2 mRNA in testicular biopsy samples from azoospermic men.

DAZ4 DAZ1 DAZ3 DAZ2

4.85e-10858411869379
Pubmed

A Gene Regulatory Program for Meiotic Prophase in the Fetal Ovary.

DAZ4 DAZ1 DAZ3 DAZ2

8.72e-10958426378784
Pubmed

Dazl deficiency leads to embryonic arrest of germ cell development in XY C57BL/6 mice.

DAZ4 DAZ1 DAZ3 DAZ2

8.72e-10958416310179
Pubmed

Embryoid bodies from mouse stem cells express oxytocin receptor, Oct-4 and DAZL.

DAZ4 DAZ1 DAZ3 DAZ2

8.72e-10958419695304
Pubmed

The epigenetic modifications and the anterior to posterior characterization of meiotic entry during mouse oogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

8.72e-10958428235998
Pubmed

Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

8.72e-10958420159962
Pubmed

Mice with Y chromosome deletion and reduced Rbm genes on a heterozygous Dazl1 null background mimic a human azoospermic factor phenotype.

DAZ4 DAZ1 DAZ3 DAZ2

1.45e-091058410601091
Pubmed

Analysis of Uncharacterized mKiaa1211 Expression during Mouse Development and Cardiovascular Morphogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

1.45e-091058431234534
Pubmed

Tesmin transcription is regulated differently during male and female meiosis.

DAZ4 DAZ1 DAZ3 DAZ2

1.45e-091058414648882
Pubmed

MAX controls meiotic entry in sexually undifferentiated germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.45e-091058438433229
Pubmed

Knockout mouse model and gametogenic failure.

DAZ4 DAZ1 DAZ3 DAZ2

1.45e-09105849922113
Pubmed

SYCP3-like X-linked 2 is expressed in meiotic germ cells and interacts with synaptonemal complex central element protein 2 and histone acetyltransferase TIP60.

DAZ4 DAZ1 DAZ3 DAZ2

1.45e-091058423810942
Pubmed

The CDY-related gene family: coordinated evolution in copy number, expression profile and protein sequence.

DAZ4 DAZ1 DAZ3 DAZ2

1.45e-091058412837688
Pubmed

NANOS2 suppresses the cell cycle by repressing mTORC1 activators in embryonic male germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

2.28e-091158434401671
Pubmed

Retinoic acid activates two pathways required for meiosis in mice.

DAZ4 DAZ1 DAZ3 DAZ2

3.41e-091258425102060
Pubmed

ZGLP1 is a determinant for the oogenic fate in mice.

DAZ4 DAZ1 DAZ3 DAZ2

3.41e-091258432054698
CytobandYq11.223

DAZ4 DAZ1 DAZ3 DAZ2

6.16e-0693584Yq11.223
CytobandEnsembl 112 genes in cytogenetic band chrYq11

DAZ4 DAZ1 DAZ3 DAZ2

6.57e-04311584chrYq11
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

TLN2 FRMD1 FARP2

2.27e-04504331293
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZFP42 IKZF3 ZBTB48 ZNF740 ZNF721 ZNF30 ZFP62

1.40e-0371843728
GeneFamilyRNA binding motif containing

DAZ4 DAZ1 DAZ3 DAZ2

1.61e-03213434725
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF19 FARP2

1.08e-0266432722
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SH3BP2 SPTBN2 FARP2

1.29e-02206433682
GeneFamilySterile alpha motif domain containing

SEC23IP L3MBTL4

1.86e-0288432760
CoexpressionTESAR_JAK_TARGETS_MOUSE_ES_D3_DN

ZFP42 DAZ4 DAZ1 DAZ3 DAZ2

3.48e-1112585MM742
CoexpressionSASAI_TARGETS_OF_CXCR6_AND_PTCH1_DN

DAZ4 DAZ1 DAZ3 DAZ2

1.05e-0812584MM781
CoexpressionWAGSCHAL_EHMT2_TARGETS_UP

DAZ4 DAZ1 DAZ3 DAZ2

1.85e-0723584MM1293
CoexpressionMATZUK_SPERMATOGONIA

DAZ4 DAZ1 DAZ3 DAZ2

6.49e-0731584MM765
CoexpressionCHEN_ETV5_TARGETS_TESTIS

DAZ4 DAZ1 DAZ3 DAZ2

8.42e-0733584MM701
CoexpressionMADAN_DPPA4_TARGETS

DAZ4 DAZ1 DAZ3 DAZ2

4.00e-0586584MM1312
CoexpressionJACKSON_DNMT1_TARGETS_UP

DAZ4 DAZ1 DAZ3 DAZ2

5.44e-0593584MM1185
CoexpressionQI_PLASMACYTOMA_DN

PDGFRA GNE P4HB FARP2

6.68e-0598584M1852
CoexpressionQI_PLASMACYTOMA_DN

PDGFRA GNE P4HB FARP2

7.22e-05100584MM775
CoexpressionGSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_AND_ROSIGLITAZONE_STIM_DN

ARHGAP5 ZNF740 XPC TRAPPC8 FUT8

7.56e-05197585M7921
CoexpressionGSE43863_TFH_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP

RNF213 FUT8 CBLB AQR ZFP62

7.93e-05199585M9750
CoexpressionGSE8835_CD4_VS_CD8_TCELL_UP

SLF2 LMBR1 ZFP62 RAD54L NUP205

8.12e-05200585M6254
Drugboron trichloride

DAZ4 DAZ1 DAZ3 DAZ2

5.66e-106584CID000025135
Drugdesmethylazelastine

DAZ4 DAZ1 DAZ3 DAZ2

6.74e-0816584CID000162558
Drugmolybdenum disulfide

DAZ4 DAZ1 DAZ3 DAZ2 FARP2

8.04e-0843585CID000014823
Drugdazmegrel

DAZ4 DAZ1 DAZ3 DAZ2

1.43e-0719584CID000053555
DrugYM 026

DAZ4 DAZ1 DAZ3 DAZ2

1.43e-0719584CID000004443
DrugAZFd

DAZ4 DAZ1 DAZ3 DAZ2

3.24e-0723584CID000196489
Drugdansylaziridine

DAZ4 DAZ1 DAZ3 DAZ2

3.24e-0723584CID000104008
Drugd-gluconhydroximo-1,5-lactam

DAZ4 DAZ1 DAZ3 DAZ2

1.13e-0631584CID000003479
Drugp11-13

DAZ4 SPSB1 DAZ1 DAZ3 DAZ2

1.35e-0675585CID000015759
DrugVistar

DAZ4 DAZ1 DAZ3 DAZ2

2.10e-0636584CID000040896
Drug3-bromo-7-nitroindazole

DAZ4 DAZ1 DAZ3 DAZ2

2.10e-0636584CID000001649
Drug2-chlorodideoxyadenosine

DAZ4 DAZ1 DAZ3 DAZ2

4.34e-0643584CID000072194
Drugpropham

DAZ4 DAZ1 DAZ3 DAZ2

4.77e-0644584CID000024685
Drugridogrel

DAZ4 DAZ1 DAZ3 DAZ2

9.37e-0652584CID005362391
DrugCyproheptadine hydrochloride [969-33-5]; Down 200; 12.4uM; PC3; HG-U133A

B4GAT1 SLF2 SH3BP2 SEC23IP ANKLE2 PPID

1.08e-051975861938_DN
Drugazafagomine

DAZ4 DAZ1 DAZ3 DAZ2

1.35e-0557584CID011957435
DrugNSC56408

DAZ4 DAZ1 DAZ3 DAZ2

1.89e-0562584CID000005604
Drugkt S

DAZ4 DAZ1 DAZ3 DAZ2

2.43e-0566584CID006399216
Drugazelastine

DAZ4 DAZ1 DAZ3 DAZ2

3.82e-0574584CID000002267
DrugBW755C

DAZ4 DAZ1 DAZ3 DAZ2

9.35e-0593584CID000047795
Drugbipy

DAZ4 DAZ1 DAZ3 DAZ2

1.10e-0497584CID000001474
DiseaseMale sterility due to Y-chromosome deletions

DAZ4 DAZ1 DAZ3 DAZ2

6.46e-108534C2931163
DiseasePartial chromosome Y deletion

DAZ4 DAZ1 DAZ3 DAZ2

6.46e-108534C1507149
DiseaseSpermatogenic Failure, Nonobstructive, Y-Linked

DAZ1 DAZ3 DAZ2

3.01e-0616533C1839071
DiseaseSPERMATOGENIC FAILURE, Y-LINKED, 2

DAZ1 DAZ3 DAZ2

3.01e-0616533415000
DiseaseSpermatogenic failure, Y-linked, 2

DAZ1 DAZ3 DAZ2

3.01e-0616533cv:C1839071
Diseaseeosinophil percentage of granulocytes

IKZF3 SPSB1 IRAK2 FARP2

8.32e-04234534EFO_0007996
Diseasepancreatic cancer (is_implicated_in)

PDGFRA XPC RAD54L

1.09e-03112533DOID:1793 (is_implicated_in)
Diseasechronic lymphocytic leukemia

ENPP1 SEC23IP FARP2

1.29e-03119533EFO_0000095
Diseasevenous thromboembolism

ENPP1 SPSB1 FRMD1 CSGALNACT1 NUP205

1.40e-03460535EFO_0004286

Protein segments in the cluster

PeptideGeneStartEntry
KLLKELIRKGIPHHF

EVI5L

106

Q96CN4
KAGFLHHVKKSDPER

ANKLE2

546

Q86XL3
LTFKGDHKHEFKRLI

CSGALNACT1

226

Q8TDX6
DHKHEFKRLILFRPF

CSGALNACT1

231

Q8TDX6
KAKKLDFRSHDKIPH

CRYBG3

566

Q68DQ2
LVHKGFKEALKFHPQ

B4GAT1

371

O43505
RREIGHFHEKKDLPL

SH3BP2

126

P78314
NEEHHRLLKGAPFKL

C4orf47

181

A7E2U8
HAALKRHDLVKLGFK

AQR

1041

O60306
IHFHGKKLKLGPAIR

DAZ2

101

Q13117
IHFHGKKLKLGPAIR

DAZ3

101

Q9NR90
HEFKKHFELPILKGR

RAD54L

351

Q92698
VHLLDKILKKHKPDF

NUP205

36

Q92621
IHLSKKIHFEGKIFP

ARHGEF19

571

Q8IW93
HHPEKPKKELDIFGL

PDGFRA

696

P16234
RGHRHGKPFVFKKLR

IRAK2

226

O43187
EKLIIHLRKHGIPFA

PUDP

96

Q08623
EELFKALGLHKLHLP

LMBR1

456

Q8WVP7
KHRRHDLPLEGAKVF

CBLB

641

Q13191
KHELHIPKGYRKDKF

L3MBTL4

146

Q8NA19
LKHFLPKRLHFAKSD

ENPP1

491

P22413
EFCHRFLEGKIKPHL

P4HB

341

P07237
LEDVPVHFFRLHKDK

FRMD1

256

Q8N878
VHFFRLHKDKKEGRP

FRMD1

261

Q8N878
IHFHGKKLKLGPAIR

DAZ1

101

Q9NQZ3
IHFHGKKLKLGPAIR

DAZ1

266

Q9NQZ3
IHFHGKKLKLGPAIR

DAZ1

431

Q9NQZ3
RKKGIEHHPNFRAVK

GNE

266

Q9Y223
KKHFPDFRGDPHRLE

GNA12

311

Q03113
KHFHKPEKERGSLTL

DENND5A

1121

Q6IQ26
IHFHGKKLKLGPAIR

DAZ4

101

Q86SG3
IHFHGKKLKLGPAIR

DAZ4

266

Q86SG3
KKSLFRHLLHGKEPQ

CCDC168

3816

Q8NDH2
KRKRFLIKLHPEVHG

FARP2

276

O94887
LLRHIKLHTGEKPFK

IKZF3

161

Q9UKT9
THKGKIPKDEHILRF

SEC14L5

256

O43304
KKLGFKHPVIGVHVR

FUT8

351

Q9BYC5
RHAFLELKFPHKEKP

SULT1C3

86

Q6IMI6
KVLKDPGRHQRHLEK

RGS22

441

Q8NE09
LHFKGCPFHRIIKKF

PPID

66

Q08752
RKPKILEEGPFHKIH

SLFN11

156

Q7Z7L1
RLHALKEIVKKFHPV

ARHGAP5

1366

Q13017
IPHHKGRKRLHLELK

SEC23IP

846

Q9Y6Y8
DGPHQKEKFIKHIAL

SLF2

366

Q8IX21
AGIFKHLKESHLPKL

BROX

151

Q5VW32
HAGFPKLAEKTRHFK

ANKDD1B

501

A6NHY2
KVVIDKHPVRFFVHK

CTDNEP1

96

O95476
DHKPRDGFHLVKDKA

RNF213

4536

Q63HN8
LKVHNRKHTGEKPFE

ZBTB48

306

P10074
FVKHGRIHTGEKPLK

ZNF30

191

P17039
HKHRPDLLDFESLKK

SPTBN2

216

O15020
FVKEDDKLIFHRHPV

SPSB1

66

Q96BD6
HFEKLERVDGPKHSL

RRAGA

296

Q7L523
RDHFLEKFGPLKHMV

VPS18

356

Q9P253
FAKHKRIHTGEKPFE

ZNF721

476

Q8TF20
EKNLFPKEILHHERK

WDR49

666

Q8IV35
KPLRFRGVHHAFAKI

SLC25A27

166

O95847
GHPETLEKFDKFKHL

MB

36

P02144
KLKRHFLVHTGEKPF

ZFP42

231

Q96MM3
PHVEHKHKPGFLDLK

TLN2

251

Q9Y4G6
LISHKRVHLGEKPFK

ZFP62

716

Q8NB50
GEESKVARLKLFPHH

TRAPPC8

816

Q9Y2L5
DFPSDLKKAHHLKRG

XPC

101

Q01831
LKRHILIHTGEKPFE

ZNF740

116

Q8NDX6