Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionendopeptidase activity

HGFAC C1S ERVK-19 TMPRSS5 CAPN5 OVCH1 F10 F11

1.25e-07430298GO:0004175
GeneOntologyMolecularFunctionpeptidase activity

HGFAC C1S ERVK-19 TMPRSS5 CAPN5 OVCH1 F10 F11 USP47

2.29e-07654299GO:0008233
GeneOntologyMolecularFunctionserine-type endopeptidase activity

HGFAC C1S TMPRSS5 OVCH1 F10 F11

2.72e-07190296GO:0004252
GeneOntologyMolecularFunctionserine-type peptidase activity

HGFAC C1S TMPRSS5 OVCH1 F10 F11

4.49e-07207296GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

HGFAC C1S TMPRSS5 OVCH1 F10 F11

5.17e-07212296GO:0017171
MousePhenomyopathy

OBSCN LAMA2 MTM1

6.90e-0554213MP:0000751
MousePhenocentrally nucleated skeletal muscle fibers

OBSCN LAMA2 MTM1

2.23e-0480213MP:0009404
MousePhenoabnormal sarcolemma morphology

OBSCN LAMA2

2.23e-0415212MP:0004121
DomainTRYPSIN_SER

HGFAC C1S TMPRSS5 OVCH1 F10 F11

2.88e-0990276IPR033116
DomainTRYPSIN_HIS

HGFAC C1S TMPRSS5 OVCH1 F10 F11

6.54e-09103276IPR018114
DomainTRYPSIN_SER

HGFAC C1S TMPRSS5 OVCH1 F10 F11

7.78e-09106276PS00135
DomainTRYPSIN_HIS

HGFAC C1S TMPRSS5 OVCH1 F10 F11

8.24e-09107276PS00134
DomainPeptidase_S1A

HGFAC C1S TMPRSS5 OVCH1 F10 F11

1.14e-08113276IPR001314
DomainTRYPSIN_DOM

HGFAC C1S TMPRSS5 OVCH1 F10 F11

1.27e-08115276PS50240
DomainTryp_SPc

HGFAC C1S TMPRSS5 OVCH1 F10 F11

1.41e-08117276SM00020
DomainTrypsin

HGFAC C1S TMPRSS5 OVCH1 F10 F11

1.73e-08121276PF00089
DomainTrypsin_dom

HGFAC C1S TMPRSS5 OVCH1 F10 F11

1.73e-08121276IPR001254
DomainPeptidase_S1_PA

HGFAC C1S TMPRSS5 OVCH1 F10 F11

1.91e-08123276IPR009003
DomainEGF-like_dom

TENM1 LAMA2 HGFAC C1S F10 SLIT3

1.24e-06249276IPR000742
DomainEGF_1

TENM1 LAMA2 HGFAC C1S F10 SLIT3

1.42e-06255276PS00022
DomainEGF-like_CS

TENM1 LAMA2 HGFAC C1S F10 SLIT3

1.63e-06261276IPR013032
DomainEGF_2

TENM1 LAMA2 HGFAC C1S F10 SLIT3

1.78e-06265276PS01186
DomainEGF_3

TENM1 HGFAC C1S F10 SLIT3

1.95e-05235275PS50026
DomainEGF

TENM1 LAMA2 HGFAC F10 SLIT3

1.95e-05235275SM00181
DomainEGF

HGFAC C1S F10 SLIT3

3.07e-05126274PF00008
DomainEGF_Ca-bd_CS

C1S F10 SLIT3

3.63e-0497273IPR018097
DomainEGF_CA

C1S F10 SLIT3

3.85e-0499273PS01187
DomainEGF-type_Asp/Asn_hydroxyl_site

C1S F10 SLIT3

4.71e-04106273IPR000152
DomainEGF_CA

C1S F10 SLIT3

7.09e-04122273SM00179
DomainEGF-like_Ca-bd_dom

C1S F10 SLIT3

7.44e-04124273IPR001881
DomainLRRCT

LRRC24 SLIT3

9.72e-0432272PF01463
DomainLAM_G_DOMAIN

LAMA2 SLIT3

1.37e-0338272PS50025
DomainLaminin_G_2

LAMA2 SLIT3

1.52e-0340272PF02210
DomainLamG

LAMA2 SLIT3

1.83e-0344272SM00282
DomainCUB

C1S OVCH1

2.27e-0349272PF00431
DomainCUB

C1S OVCH1

2.36e-0350272SM00042
Domain-

C1S OVCH1

2.55e-03522722.60.120.290
DomainCUB

C1S OVCH1

2.65e-0353272PS01180
DomainCUB_dom

C1S OVCH1

3.06e-0357272IPR000859
DomainLaminin_G

LAMA2 SLIT3

3.16e-0358272IPR001791
DomainConA-like_dom

LAMA2 TRIM58 SLIT3

3.78e-03219273IPR013320
DomainCys-rich_flank_reg_C

LRRC24 SLIT3

7.45e-0390272IPR000483
DomainLRRCT

LRRC24 SLIT3

7.45e-0390272SM00082
Domain-

LAMA2 SLIT3

8.27e-03952722.60.120.200
DomainLRRNT

LRRC24 SLIT3

8.78e-0398272IPR000372
DomainLRRNT

LRRC24 SLIT3

8.78e-0398272SM00013
DomainASX_HYDROXYL

C1S F10

9.13e-03100272PS00010
PathwayREACTOME_DEFECTIVE_FACTOR_IX_CAUSES_HEMOPHILIA_B

F10 F11

6.84e-059202M39001
PathwayKEGG_COMPLEMENT_AND_COAGULATION_CASCADES

C1S F10 F11

1.21e-0469203M16894
PathwayREACTOME_DEFECTS_OF_CONTACT_ACTIVATION_SYSTEM_CAS_AND_KALLIKREIN_KININ_SYSTEM_KKS

F10 F11

2.27e-0416202M38996
PathwayWP_COMPLEMENT_SYSTEM

C1S F10 F11

3.21e-0496203M39581
PathwayREACTOME_DISEASES_OF_HEMOSTASIS

F10 F11

3.22e-0419202M48230
PathwayWP_BLOOD_CLOTTING_CASCADE

F10 F11

4.34e-0422202M39480
PathwayBIOCARTA_INTRINSIC_PATHWAY

F10 F11

4.75e-0423202M15997
PathwayREACTOME_INTRINSIC_PATHWAY_OF_FIBRIN_CLOT_FORMATION

F10 F11

4.75e-0423202M14766
PathwayBIOCARTA_INTRINSIC_PATHWAY

F10 F11

4.75e-0423202MM1427
PathwayWP_BLOOD_CLOTTING_CASCADE

F10 F11

4.75e-0423202MM15936
PathwayREACTOME_INTRINSIC_PATHWAY_OF_FIBRIN_CLOT_FORMATION

F10 F11

4.75e-0423202MM14557
PathwayREACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE

F10 F11

1.37e-0339202M2844
PathwayREACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE

F10 F11

1.37e-0339202MM14559
Pubmed

Associations of coagulation factor X and XI with incident acute coronary syndrome and stroke: A nested case-control study.

F10 F11

6.71e-07229234351069
Pubmed

Gene targeting of tissue factor, factor X, and factor VII in mice: their involvement in embryonic development.

F10 F11

2.01e-06329211841337
Pubmed

Apixaban, a direct factor Xa inhibitor, inhibits tissue-factor induced human platelet aggregation in vitro: comparison with direct inhibitors of factor VIIa, XIa and thrombin.

F10 F11

6.70e-06529220589316
Pubmed

Purification and characterization of plasma protein C inhibitor.

F10 F11

1.41e-0572922551064
Pubmed

A CpG mutational hotspot in a ONECUT binding site accounts for the prevalent variant of hemophilia B Leyden.

F10 F11

1.87e-05829223472758
Pubmed

AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis.

LAMA2 MTM1

3.01e-051029218434328
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

LAMA2 HGFAC C1S F11

5.98e-0525729416335952
Pubmed

Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.

TENM1 LAMA2

1.53e-042229235245678
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

OBSCN ST3GAL1 SPIRE2 LRRC24 ATP13A2 SLC1A5

2.57e-04110529635748872
Pubmed

Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors.

LAMA2 SLIT3

6.50e-044529222696295
InteractionSERPINA5 interactions

HGFAC F10 F11

2.47e-0541283int:SERPINA5
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

OBSCN LRRC24

1.22e-02161192593
CoexpressionBOQUEST_STEM_CELL_UP

TENM1 LAMA2 C1S F10 SLIT3

7.68e-06261285M1834
CoexpressionHALLMARK_COAGULATION

C1S CAPN5 F10 F11

1.37e-05138284M5946
CoexpressionHALLMARK_XENOBIOTIC_METABOLISM

HGFAC SLC1A5 F10 F11

5.83e-05200284M5934
ToppCellFibroblasts|World / lung cells shred on cell class, cell subclass, sample id

LAMA2 C1S CAPN5 F10 SLIT3

1.46e-07199285e2b6752fcabd5249a166486ae6796f2c97c1fcaf
ToppCell(5)_Fibroblast-D|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

LAMA2 C1S CAPN5 F10 SLIT3

1.46e-071992853f415620ad8b8d8c6871e1353e13f87b281fcc0e
ToppCell(5)_Fibroblasts|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

LAMA2 C1S CAPN5 F10 SLIT3

1.49e-0720028522c839f27d3abdf86bfabdfa305f205dd899a9dc
ToppCellFibroblast|World / shred by cell class for parenchyma

LAMA2 C1S CAPN5 F10 SLIT3

1.49e-07200285dec9ce1bc2571197003596f32e5f742ede72aa79
ToppCell-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

LAMA2 C1S CAPN5 SLIT3

3.67e-061692848ebe9a88111c53a09c25a7b6a164a0a17880458d
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMA2 C1S EDA2R SLIT3

3.67e-06169284335619507857383c3b0b507cdf05d786ed59e585
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OBSCN LAMA2 DPYSL4 C1S

4.40e-06177284bd602db857f37869ef76d14c05ef522c509f08ee
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

4.50e-0617828478a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

LAMA2 C1S CAPN5 SLIT3

4.60e-0617928410fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

LAMA2 C1S F10 SLIT3

5.24e-06185284fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 C1S F10 SLIT3

5.36e-0618628407d94d5d1c2fe7bb909a07ca81058a0eabc65c60
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 C1S F10 SLIT3

5.59e-06188284e18065bbc26d6f3774fd1f478fb41d8fb555fa26
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

THSD4 LAMA2 C1S F10

5.71e-06189284eccf3d49354a67c94f1ed7c15a98a48a5e8e2ed0
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA2 C1S SLC1A5 SLIT3

5.71e-0618928440cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

5.71e-0618928471397e993a77d70b2eeede240bdfc7660b558987
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

5.71e-061892844eea4759520c312bd17a681034d8074e47093d2b
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

THSD4 LAMA2 C1S F10

5.71e-0618928440764f461b8aa1d3a2c5a30590b7fb9307d47d09
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

5.95e-06191284a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellASK454-Mesenchymal-Fibroblast|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

TENM1 LAMA2 C1S SLIT3

5.95e-061912841726add3f392a061536b7aff72ba84303f4a0b1f
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

THSD4 LAMA2 C1S F10

5.95e-061912845271198116343c07202649889057e5774d7fdde3
ToppCellASK440-Mesenchymal-Fibroblast|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

TENM1 LAMA2 C1S SLIT3

5.95e-06191284387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCellASK440-Mesenchymal|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

TENM1 LAMA2 C1S SLIT3

5.95e-06191284f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

5.95e-061912848f6d592edc32fdb901af30501d4360512334e8c2
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA2 C1S SLC1A5 SLIT3

5.95e-06191284997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCellASK454-Mesenchymal|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

TENM1 LAMA2 C1S SLIT3

5.95e-06191284e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.07e-06192284bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.07e-061922845105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.07e-06192284d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA2 C1S F10 SLIT3

6.07e-06192284e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 C1S SLC1A5 SLIT3

6.07e-06192284beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.07e-061922840ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 C1S SLC1A5 SLIT3

6.07e-061922845876ff75e273a48e7ad8236423fb41e4ae4c0a91
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

THSD4 LAMA2 C1S F10

6.20e-0619328409de51f8ac509e03d480ed3dc9dfe7e7defc59cb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.20e-061932845b602b1702283184bd3943c2a6f2290b7c37e407
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.20e-06193284c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

THSD4 LAMA2 C1S F10

6.20e-061932843d85c28f6ebdcb15e875ad01d52d6c138fbf8525
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.33e-0619428490efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.33e-06194284e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.33e-06194284df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.46e-06195284d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 C1S F10 SLIT3

6.46e-061952841236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.46e-06195284783bfa8110161cbd6def50ce849cae676c39c458
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.46e-06195284cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCellIPF-Stromal-Fibroblast|World / Disease state, Lineage and Cell class

LAMA2 C1S F10 SLIT3

6.46e-061952849c32756edb54f0c211185d9a98073fe01fd1526a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.59e-06196284a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.59e-061962843a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCellLAM-Mesenchyme|LAM / Condition, Lineage and Cell class

LAMA2 C1S F10 SLIT3

6.59e-06196284e7918b0cd5eeb675012f871f43f4388471845035
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.59e-061962843e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.59e-06196284bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCellIPF-Stromal-Fibroblast|IPF / Disease state, Lineage and Cell class

LAMA2 C1S F10 SLIT3

6.59e-06196284f7ae604ba32b322d86d68b2b54892e7c6ab06c49
ToppCellLAM-Mesenchyme-Mesenchyme|LAM / Condition, Lineage and Cell class

LAMA2 C1S F10 SLIT3

6.59e-061962844590fb157797a68dca4295e203702bbae279cd03
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TENM1 LAMA2 C1S SLIT3

6.72e-0619728444673c38384453207871d3fd8e8ba9093cc06bc5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.72e-0619728409946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMA2 C1S F10 SLIT3

6.72e-0619728417344464fdcc5ba0c03959696b97c195f11e644c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.72e-061972846d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellCOPD-Stromal|COPD / Disease state, Lineage and Cell class

LAMA2 C1S F10 SLIT3

6.72e-06197284d5390d86acaa8c39f1da893e8d2271f9ed2951d7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.72e-06197284ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 C1S F10 SLIT3

6.72e-06197284c747c496ac090309b7f8a3e9d840928f12c83f2f
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMA2 C1S F10 SLIT3

6.72e-061972843bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMA2 C1S SLIT3

6.72e-0619728437f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMA2 C1S F10 SLIT3

6.72e-061972845b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCell3'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA2 C1S F10 SLIT3

6.86e-06198284abac765c4f6864bdb1700bc546c3b9771edc25c3
ToppCelltumor_Lung-Fibroblasts-COL13A1+_matrix_FBs|tumor_Lung / Location, Cell class and cell subclass

LAMA2 C1S F10 SLIT3

6.86e-061982842d7842f352273b6b823c86eb548b9f4a4cddf0ae
ToppCell3'-Adult-LymphNode-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA2 C1S F10 SLIT3

6.86e-06198284ff57addcbdd53e5d2d0c80ec76b5eab3b3a67ca2
ToppCellCOPD-Stromal-Fibroblast|World / Disease state, Lineage and Cell class

LAMA2 C1S F10 SLIT3

6.86e-061982842f13c0b3372af53d1bd85f9546f315c878580a71
ToppCellCOPD-Stromal-Fibroblast|COPD / Disease state, Lineage and Cell class

LAMA2 C1S F10 SLIT3

6.86e-061982847904af61473cb20064f7a3a1e1bfe8d5913cf317
ToppCell5'-Parenchyma_lung-Mesenchymal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 C1S F10 SLIT3

6.86e-06198284aae663c6da70b6e716edeed50cc7d3962d78e697
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 C1S F10 SLIT3

7.00e-061992844032f03a4165f5f2a90ef1d8315cc743ce9075bb
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TENM1 LAMA2 C1S SLIT3

7.00e-06199284e1f1950d6f840485e263b83dc81b98910be3ae7a
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 C1S F10 SLIT3

7.00e-061992840019cfaa586a450c2e4952d1184a540561c8d0ba
ToppCelldistal-mesenchymal-Alveolar_Fibroblast-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMA2 C1S F10 SLIT3

7.00e-0619928428c1722deef3b8347371c7359be7c64b95780de3
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LAMA2 C1S F10 SLIT3

7.00e-06199284dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCell368C-Fibroblasts-Fibroblast-D-|368C / Donor, Lineage, Cell class and subclass (all cells)

LAMA2 C1S F10 SLIT3

7.00e-061992845a425e7d11c5911ff5855c27a7f058a7ed7abbb0
ToppCell356C-Fibroblasts-Fibroblast-F|356C / Donor, Lineage, Cell class and subclass (all cells)

LAMA2 C1S F10 SLIT3

7.00e-0619928459fe5f3c6338e019a149ab135acf9cc5657298bf
ToppCell(5)_Fibroblast-A_(Fibroblast_progenitors)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

LAMA2 C1S CAPN5 SLIT3

7.00e-06199284b783917fe0a9725a680aa430a42f02ce294900ef
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA2 C1S F10 SLIT3

7.00e-0619928466a79732caf2f04c09b4d9832377aa01ca477677
ToppCell368C-Fibroblasts|368C / Donor, Lineage, Cell class and subclass (all cells)

LAMA2 C1S F10 SLIT3

7.00e-06199284dbf64b83e2dc311b68f299c3f306ee098efd664c
ToppCell368C-Fibroblasts-Fibroblast-D|368C / Donor, Lineage, Cell class and subclass (all cells)

LAMA2 C1S F10 SLIT3

7.00e-0619928466545eb7f65e450b742628fd431956e13330a0d3
ToppCell(5)_Fibroblast-F|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

LAMA2 C1S CAPN5 SLIT3

7.00e-061992841f66db4f502de4a5159cde90fcb3befb26b8d375
ToppCell356C-Fibroblasts-Fibroblast-F-|356C / Donor, Lineage, Cell class and subclass (all cells)

LAMA2 C1S F10 SLIT3

7.00e-06199284136f24597ddca5cf2175120975c94782a3232ec6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LAMA2 C1S F10 SLIT3

7.00e-06199284c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 C1S F10 SLIT3

7.00e-061992844e128c705ad36fd840582848f278770f356fcc8b
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 C1S F10 SLIT3

7.00e-06199284a538da095ba996ee96e263442cf5b6ba9178f3d4
ToppCellmedial-2-mesenchymal|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMA2 C1S F10 SLIT3

7.14e-06200284a9d8aa5bcf383d98a9e2eaf4b1f8466982d6b088
ToppCellParenchymal-10x3prime_v2-Stromal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA2 C1S F10 SLIT3

7.14e-06200284f6be0f24e607abb9007823a54fb0b24d04990a89
ToppCellBiopsy_Control_(H.)-Mesenchymal-Fibroblasts|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

LAMA2 C1S F10 SLIT3

7.14e-062002848d75ce89393df452defacf2ec9a5bd4b7708afbb
ToppCellcellseq-Mesenchymal-Fibroblastic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA2 C1S F10 SLIT3

7.14e-062002848978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCellcellseq-Mesenchymal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA2 C1S F10 SLIT3

7.14e-06200284238285fc372ce2e5e4341fc3084a3a833bf4a0a6
ToppCellBiopsy_IPF-Mesenchymal-PLIN2+_Fibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

LAMA2 C1S F10 SLIT3

7.14e-062002842c5626ea8fb4b702d4560117e53edf6cfcf1971e
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAMA2 C1S F10 SLIT3

7.14e-062002840b2614b8513693dd508c9003699049efd9abac52
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA2 C1S F10 SLIT3

7.14e-0620028428e5354008adf97b17333f17f8cbef930db6729a
ToppCellParenchyma_Control_(B.)-Stromal-TX|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

LAMA2 C1S F10 SLIT3

7.14e-062002840a86656d48e4238d0e4d592d477d29f7ba7c2ec0
ToppCell356C-Fibroblasts|356C / Donor, Lineage, Cell class and subclass (all cells)

LAMA2 C1S F10 SLIT3

7.14e-062002849c95329f0b26ff378de803030d4c28517b3adc85
ToppCellBiopsy_Other_PF-Mesenchymal-Fibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

LAMA2 C1S F10 SLIT3

7.14e-062002849996b6887cf2b1936e10a1aa396f09fd8da5f4c4
ToppCellproximal-3-mesenchymal-Adventitial_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMA2 C1S F10 SLIT3

7.14e-06200284869d45b71efd395d050873db5fee2ed0443d5e6f
ToppCelldistal-2-mesenchymal-Alveolar_Fibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMA2 C1S F10 SLIT3

7.14e-0620028412b705dabec1b3752a488a891eda1a5123fcdc41
ToppCellTracheal-10x3prime_v2-Stromal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA2 C1S F10 SLIT3

7.14e-06200284f74b9b0e27afedd589e828d30194e8417029817a
ToppCellBiopsy_Control_(H.)-Mesenchymal|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

LAMA2 C1S F10 SLIT3

7.14e-0620028401522ed0b68614b1ebdf190957d44a9d48a6c6e3
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA2 C1S F10 SLIT3

7.14e-062002843a164e3971bcd62b148b813171c103adb81f972e
ToppCellSkin-Fibroblasts|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

LAMA2 C1S F10 SLIT3

7.14e-06200284f777eadf571a1a6d246da87346a9cb9d511c2e81
ComputationalSerine proteases.

C1S F10 F11

2.39e-0539163MODULE_109
ComputationalCatabolic peptidases.

C1S CAPN5 F10

2.84e-0489163MODULE_209
ComputationalGenes in the cancer module 172.

C1S CAPN5 F10

3.55e-0496163MODULE_172
ComputationalMetal / Ca ion binding.

C1S F10 SLIT3

9.22e-04133163MODULE_324
DrugAC1N17P1

C1S F10 F11

5.81e-087283CID003976779
Drug4-chloro-3-ethoxy-7-guanidinoisocoumarin

C1S F10 F11

4.72e-0713283CID000196678
DrugAC1NDIV9

C1S F10 F11

1.99e-0543283CID004601953
DrugS-2648

C1S F10 F11

2.60e-0547283CID000123687
Drugbenzamidine

HGFAC C1S F10 F11

3.03e-05147284CID000002332
DrugCoagulation Factor IX

F10 F11

3.05e-057282DB00100
DrugAC1N4DEC

TENM1 F10 F11

3.14e-0550283CID000001495
Drugdihydroxyacetophenone

F10 F11

4.07e-058282CID000099611
Drug6-amino-1-naphthalenesulfonamide

F10 F11

7.97e-0511282CID000071009
DrugBetonicine [515-25-3]; Up 200; 25.2uM; HL60; HT_HG-U133A

HGFAC UNC45A TRIM58 ATP13A2

9.28e-051962842207_UP
DrugChromozym Pk

F10 F11

9.55e-0512282CID003080855
Diseasepartial thromboplastin time

C1S F11

2.04e-0424262EFO_0004310
Diseasefactor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement

HGFAC F11

1.12e-0356262EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Diseasevenous thromboembolism, fibrinogen measurement

HGFAC F11

1.59e-0367262EFO_0004286, EFO_0004623
Diseaseneuroimaging measurement

THSD4 LAMA2 DPYSL4 SPIRE2 ATP13A2

2.16e-031069265EFO_0004346
DiseaseParkinson Disease

MTA1 ATP13A2

2.55e-0385262C0030567
Diseasecortical thickness

THSD4 LAMA2 DPYSL4 SPIRE2 ATP13A2

2.57e-031113265EFO_0004840

Protein segments in the cluster

PeptideGeneStartEntry
ASIEDQGAAAGGYCG

SLC1A5

26

Q15758
AGCYQALDGGNTADA

CAPN5

171

O15484
DAGVSGSKYDVAANG

MAGEB6

116

Q8N7X4
TGDCYSNKEGGGEDD

ITGAE

156

P38570
GKYECEASNAGGAAR

LRRC24

341

Q50LG9
CADGYFGDAVDAKNC

LAMA2

901

P24043
YFDCKSDACQGDSGG

HGFAC

586

Q04756
QAGQADAGEYSCEAG

OBSCN

951

Q5VST9
AGKADAGEYSCEAGG

OBSCN

1136

Q5VST9
AGQADAGEYSCKAGD

OBSCN

1596

Q5VST9
ADDFCQGTKAALAGG

DPYSL4

86

O14531
CGDGANDCGALKAAD

ATP13A2

876

Q9NQ11
YGCAVDGNGKDCFSA

C6orf52

61

Q5T4I8
DSCKGDSGGAFAVQD

C1S

626

P09871
AGYREGGKDACKGDS

F11

561

P03951
ADGASYPAADNGECR

FIGNL2

291

A6NMB9
GYDTKQEDACQGDSG

F10

406

P00742
AASGEKDFCQGDSGG

OVCH1

751

Q7RTY7
CDEVDLYGFGADSKG

ST3GAL1

281

Q11201
DPNCDCFSGDGGYAK

TENM1

1476

Q9UKZ4
SVCYKAGPGADNGEE

MTA1

66

Q13330
GYGGDLCDNKNDSAN

SLIT3

1396

O75094
VANKATGGGYESDDA

MTM1

286

Q13496
DSEDSGCGAADEGYG

SPIRE2

136

Q8WWL2
AYQKAGGDSGNVDDD

USP47

841

Q96K76
AGYLDGRADACQGDS

TMPRSS5

391

Q9H3S3
YAACGLDDCINGGKS

ERVK-19

936

Q9WJR5
GQCKSIGCDDYLGSD

THSD4

381

Q6ZMP0
ELSKDCGYGEGGDAY

EDA2R

26

Q9HAV5
KEGNELFKCGDYGGA

UNC45A

26

Q9H3U1
SEFCEKSDGAQGGVY

TRIM58

41

Q8NG06