Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

ERBB4 EFNA3 IGF2R FER FES NRP1

5.81e-06145626GO:0004713
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

ERBB4 EFNA3 IGF2R NRP1

4.95e-0565624GO:0004714
GeneOntologyMolecularFunctionalkaline phosphatase activity

ALPL ALPP

1.41e-046622GO:0004035
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

ERBB4 EFNA3 IGF2R NRP1

1.41e-0485624GO:0019199
GeneOntologyMolecularFunctioncalcium-independent phospholipase A2 activity

PLB1 PLA2G4C

3.37e-049622GO:0047499
GeneOntologyMolecularFunctionphospholipase activity

PLB1 PLA2G4C DDHD1 PLCG1

4.36e-04114624GO:0004620
GeneOntologyMolecularFunctionphosphatidyl phospholipase B activity

PLB1 PLA2G4C

5.12e-0411622GO:0102545
GeneOntologyMolecularFunctionO-acyltransferase activity

PLA2G4C PORCN SOAT2

8.19e-0459623GO:0008374
GeneOntologyMolecularFunctionlipase activity

PLB1 PLA2G4C DDHD1 PLCG1

8.93e-04138624GO:0016298
GeneOntologyMolecularFunctiongrowth factor binding

ERBB4 IGF2R RPS19 NRP1

1.41e-03156624GO:0019838
GeneOntologyMolecularFunctioncarboxylic ester hydrolase activity

NDST3 PLB1 PLA2G4C DDHD1

1.44e-03157624GO:0052689
GeneOntologyMolecularFunctionphospholipase A1 activity

PLA2G4C DDHD1

1.57e-0319622GO:0008970
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

NDST3 FASN PLB1 PLA2G4C DDHD1 PLCG1 ALPL ALPP

3.37e-03807628GO:0016788
GeneOntologyMolecularFunctionlysophospholipase activity

PLB1 PLA2G4C

3.65e-0329622GO:0004622
GeneOntologyMolecularFunctionphospholipase A2 activity

PLB1 PLA2G4C

5.89e-0337622GO:0004623
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

FASN PLA2G4C PORCN SOAT2

6.39e-03238624GO:0016747
GeneOntologyMolecularFunctionmodified amino acid binding

MFGE8 FASN FOLR2

6.47e-03122623GO:0072341
GeneOntologyMolecularFunctionepidermal growth factor receptor binding

ERBB4 FER

7.20e-0341622GO:0005154
DomainFA58C

CNTNAP3B MFGE8 CNTNAP3 NRP1

7.18e-0721644SM00231
DomainFA58C_3

CNTNAP3B MFGE8 CNTNAP3 NRP1

7.18e-0721644PS50022
DomainFA58C_1

CNTNAP3B MFGE8 CNTNAP3 NRP1

7.18e-0721644PS01285
DomainFA58C_2

CNTNAP3B MFGE8 CNTNAP3 NRP1

7.18e-0721644PS01286
DomainF5_F8_type_C

CNTNAP3B MFGE8 CNTNAP3 NRP1

1.27e-0624644PF00754
DomainFA58C

CNTNAP3B MFGE8 CNTNAP3 NRP1

1.27e-0624644IPR000421
DomainTyr-prot_kinase_Fes/Fps

FER FES

1.16e-052642IPR016250
DomainAlk_phosphatase

ALPL ALPP

6.90e-054642PF00245
DomainAlkaline_phosphatase_AS

ALPL ALPP

6.90e-054642IPR018299
DomainAlkaline_phosphatase

ALPL ALPP

6.90e-054642IPR001952
DomainalkPPc

ALPL ALPP

6.90e-054642SM00098
DomainALKALINE_PHOSPHATASE

ALPL ALPP

6.90e-054642PS00123
DomainDesmosomal_cadherin

DSC2 DSC3

2.40e-047642IPR009122
DomainCadherin_pro

DSC2 DSC3

2.40e-047642PF08758
DomainGalactose-bd-like

CNTNAP3B MFGE8 CNTNAP3 NRP1

3.03e-0494644IPR008979
DomainCadherin_pro_dom

DSC2 DSC3

3.19e-048642IPR014868
DomainCadherin_pro

DSC2 DSC3

3.19e-048642SM01055
DomainHEMATOPO_REC_S_F1

CSF2RB CRLF2

3.19e-048642PS01355
DomainHempt_rcpt_S_F1_CS

CSF2RB CRLF2

4.10e-049642IPR003531
DomainFN3

FNDC7 SDK2 CSF2RB TRIM42 CRLF2

4.29e-04185645SM00060
DomainFN3

FNDC7 SDK2 CSF2RB TRIM42 CRLF2

5.98e-04199645PS50853
DomainMBOAT_fam

PORCN SOAT2

6.23e-0411642IPR004299
DomainMBOAT

PORCN SOAT2

6.23e-0411642PF03062
DomainCUB

KREMEN2 CSMD2 NRP1

6.32e-0449643PF00431
DomainCUB

KREMEN2 CSMD2 NRP1

6.70e-0450643SM00042
DomainFN3_dom

FNDC7 SDK2 CSF2RB TRIM42 CRLF2

7.46e-04209645IPR003961
Domain-

KREMEN2 CSMD2 NRP1

7.52e-04526432.60.120.290
DomainCUB

KREMEN2 CSMD2 NRP1

7.96e-0453643PS01180
DomainCUB_dom

KREMEN2 CSMD2 NRP1

9.84e-0457643IPR000859
DomainAcyl_Trfase/lysoPLipase

FASN PLA2G4C

1.52e-0317642IPR016035
DomainEGF_1

CNTNAP3B LAMB4 MFGE8 RELN CNTNAP3

1.80e-03255645PS00022
Domain-

IGSF8 FNDC7 SDK2 CSF2RB TRIM42 IGSF11 EXOC2 CRLF2

1.85e-036636482.60.40.10
Domain-

MFGE8 CNTNAP3 NRP1

2.01e-03736432.60.120.260
DomainEGF_2

CNTNAP3B LAMB4 MFGE8 RELN CNTNAP3

2.13e-03265645PS01186
Domainfn3

FNDC7 SDK2 CSF2RB TRIM42

2.31e-03162644PF00041
DomainFCH

FER FES

2.55e-0322642PF00611
DomainFCH

FER FES

2.55e-0322642SM00055
DomainIg-like_fold

IGSF8 FNDC7 SDK2 CSF2RB TRIM42 IGSF11 EXOC2 CRLF2

2.74e-03706648IPR013783
DomainFCH_dom

FER FES

2.79e-0323642IPR001060
DomainCadherin_cytoplasmic-dom

DSC2 DSC3

3.30e-0325642IPR000233
DomainF_BAR

FER FES

3.30e-0325642IPR031160
DomainCadherin_C

DSC2 DSC3

3.30e-0325642PF01049
DomainF_BAR

FER FES

3.30e-0325642PS51741
DomainTyrKc

ERBB4 FER FES

3.42e-0388643SM00219
DomainTyr_kinase_cat_dom

ERBB4 FER FES

3.42e-0388643IPR020635
DomainCatenin_binding_dom

DSC2 DSC3

4.42e-0329642IPR027397
DomainARF

ARL5B ARL5A

4.42e-0329642PS51417
DomainSmall_GTPase_ARF

ARL5B ARL5A

4.42e-0329642IPR024156
Domain-

DSC2 DSC3

4.42e-03296424.10.900.10
DomainPROTEIN_KINASE_TYR

ERBB4 FER FES

4.50e-0397643PS00109
Pubmed

In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.

CNTNAP3B ERBB4 CNTNAP3

1.18e-07664334143959
Pubmed

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

ERBB4 ARL5B EED IGF2R PLA2G4C ARL5A ALPL

7.76e-0727664728319085
Pubmed

Fer kinase limits neutrophil chemotaxis toward end target chemoattractants.

FER FES

3.33e-06264223355730
Pubmed

The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.

CNTNAP3B CNTNAP3

3.33e-06264231150793
Pubmed

Modifications in a flexible surface loop modulate the isozyme-specific properties of mammalian alkaline phosphatases.

ALPL ALPP

3.33e-0626428244974
Pubmed

Fps/Fes and Fer non-receptor protein-tyrosine kinases regulate collagen- and ADP-induced platelet aggregation.

FER FES

3.33e-06264212871378
Pubmed

Closing in on the biological functions of Fps/Fes and Fer.

FER FES

3.33e-06264211994747
Pubmed

Fps/Fes and Fer protein-tyrosinekinases play redundant roles in regulating hematopoiesis.

FER FES

3.33e-06264212901971
Pubmed

Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.

CNTNAP3B CNTNAP3

3.33e-06264226807827
Pubmed

FER and FES tyrosine kinase fusions in follicular T-cell lymphoma.

FER FES

3.33e-06264231746983
Pubmed

Mammalian alkaline phosphatase catalysis requires active site structure stabilization via the N-terminal amino acid microenvironment.

ALPL ALPP

3.33e-06264216893177
Pubmed

Assignment of the human genes for desmocollin 3 (DSC3) and desmocollin 4 (DSC4) to chromosome 18q12.

DSC2 DSC3

9.99e-0636427774948
Pubmed

The defect seen in the phosphatidylinositol hydrolysis pathway in HIV-infected lymphocytes and lymphoblastoid cells is due to inhibition of the inositol 1,4,5-trisphosphate 1,3,4,5-tetrakisphosphate 5-phosphomonoesterase.

ALPL ALPP

9.99e-0636421321014
Pubmed

The Fer tyrosine kinase regulates an axon retraction response to Semaphorin 3A in dorsal root ganglion neurons.

FER FES

9.99e-06364218053124
Pubmed

cDNA cloning and expression of a novel human desmocollin.

DSC2 DSC3

9.99e-0636427929347
Pubmed

Structure and function of desmosomal proteins and their role in development and disease.

DSC2 DSC3

9.99e-06364214523549
Pubmed

Desmocollin switching in colorectal cancer.

DSC2 DSC3

9.99e-06364217088906
Pubmed

The small G protein Arl5 contributes to endosome-to-Golgi traffic by aiding the recruitment of the GARP complex to the Golgi.

ARL5B ARL5A

9.99e-06364225795912
Pubmed

Neuropilin 1 directly interacts with Fer kinase to mediate semaphorin 3A-induced death of cortical neurons.

FER NRP1

9.99e-06364220133938
Pubmed

The influence of desmocollin 1-3 expression on prognosis after curative resection of colorectal liver metastases.

DSC2 DSC3

9.99e-06364223975055
Pubmed

Compositionally different desmosomes in the various compartments of the human hair follicle.

DSC2 DSC3

9.99e-0636429810708
Pubmed

Changing pattern of desmocollin 3 expression accompanies epidermal organisation during skin development.

DSC2 DSC3

9.99e-0636429389456
Pubmed

Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors.

ERBB4 FER FES PLCG1

1.28e-057764422973453
Pubmed

Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.

ERBB4 FER FES

1.33e-052564315254900
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

IGSF8 PCYOX1L FASN IGF2R COPB2 ALPL ALPP CDC45

1.65e-0561364822268729
Pubmed

TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation.

CSF2RB CRLF2

2.00e-05464221841801
Pubmed

Structural evidence of functional divergence in human alkaline phosphatases.

ALPL ALPP

2.00e-05464212372831
Pubmed

Involvement of Fes/Fps tyrosine kinase in semaphorin3A signaling.

FES NRP1

2.00e-05464212093729
Pubmed

Stage-specific expression patterns of alkaline phosphatase during development of the first arch skeleton in inbred C57BL/6 mouse embryos.

ALPL ALPP

2.00e-0546429061447
Pubmed

Plakoglobin as a regulator of desmocollin gene expression.

DSC2 DSC3

2.00e-05464223652796
Pubmed

Inactivation of two mouse alkaline phosphatase genes and establishment of a model of infantile hypophosphatasia.

ALPL ALPP

2.00e-0546429056646
Pubmed

A quantitative protein interaction network for the ErbB receptors using protein microarrays.

ERBB4 FER FES PLCG1

2.37e-059064416273093
Pubmed

Genetic evidence for Dnmt3a-dependent imprinting during oocyte growth obtained by conditional knockout with Zp3-Cre and complete exclusion of Dnmt3b by chimera formation.

IGF2R ALPL

3.32e-05564220132320
Pubmed

Loss of desmocollin 1-3 and homeobox genes PITX1 and CDX2 are associated with tumor progression and survival in colorectal carcinoma.

DSC2 DSC3

3.32e-05564222438068
Pubmed

Genetic and physical mapping of the fitness 1 (fit1) locus within the Fes-Hbb region of mouse chromosome 7.

EED FES

3.32e-0556427767008
Pubmed

Granulocyte-macrophage colony-stimulating factor stimulates JAK2 signaling pathway and rapidly activates p93fes, STAT1 p91, and STAT3 p92 in polymorphonuclear leukocytes.

CSF2RB FES

3.32e-0556428631962
Pubmed

Central role of pyrophosphate in acellular cementum formation.

ALPL ALPP

3.32e-05564222675556
Pubmed

Two alkaline phosphatase genes are expressed during early development in the mouse embryo.

ALPL ALPP

3.32e-0556422133555
Pubmed

Chromosomal assignment of the human genes coding for the major proteins of the desmosome junction, desmoglein DGI (DSG), desmocollins DGII/III (DSC), desmoplakins DPI/II (DSP), and plakoglobin DPIII (JUP).

DSC2 DSC3

3.32e-0556421889810
Pubmed

Neuropilin-1 expression in cancer and development.

LYVE1 NRP1

3.32e-05564222025255
Pubmed

Phospholipase Cgamma2 is necessary for separation of blood and lymphatic vasculature in mice.

LYVE1 PLCG1

3.32e-05564219056831
Pubmed

Nomenclature of the desmosomal cadherins.

DSC2 DSC3

3.32e-0556428486729
Pubmed

Requirement for early-generated neurons recognized by monoclonal antibody lot1 in the formation of lateral olfactory tract.

RELN NRP1

3.32e-0556429742149
Pubmed

Germ cell nuclear antigen (GCNA1) expression does not require a gonadal environment or steroidogenic factor 1: examination of GCNA1 in ectopic germ cells and in Ftz-F1 null mice.

ALPL ALPP

3.32e-0556429291464
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

MFGE8 RELN PLCG1 ALPL ALPP

4.37e-0521064516537572
Pubmed

Control of vesicle fusion by a tyrosine phosphatase.

FER FES

4.98e-05664215322554
Pubmed

Dissection of the odontoblast differentiation process in vitro by a combination of FGF1, FGF2, and TGFbeta1.

ALPL ALPP

4.98e-05664210878613
Pubmed

Fer and Fps/Fes participate in a Lyn-dependent pathway from FcepsilonRI to platelet-endothelial cell adhesion molecule 1 to limit mast cell activation.

FER FES

4.98e-05664216731527
Pubmed

Oligomerization but Not Membrane Bending Underlies the Function of Certain F-BAR Proteins in Cell Motility and Cytokinesis.

FER FES

4.98e-05664226702831
Pubmed

An unexpected role of semaphorin3a-neuropilin-1 signaling in lymphatic vessel maturation and valve formation.

LYVE1 NRP1

4.98e-05664222723300
Pubmed

Hierarchical expression of desmosomal cadherins during stratified epithelial morphogenesis in the mouse.

DSC2 DSC3

4.98e-0566429404003
Pubmed

Mouse desmocollin (Dsc3) and desmoglein (Dsg1) genes are closely linked in the proximal region of chromosome 18.

DSC2 DSC3

4.98e-0566427959727
Pubmed

Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.

RELN IGF2R TRIM42

5.18e-053964319010793
Pubmed

Lymphoangiocrine signals promote cardiac growth and repair.

LYVE1 RELN

6.96e-05764233299187
Pubmed

Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia.

ERBB4 PLCG1

6.96e-05764216767099
Pubmed

Fenestral diaphragms and PLVAP associations in liver sinusoidal endothelial cells are developmentally regulated.

LYVE1 NRP1

6.96e-05764231666588
Pubmed

Fer kinase is required for sustained p38 kinase activation and maximal chemotaxis of activated mast cells.

FER FES

6.96e-05764212192036
Pubmed

Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles.

LYVE1 FOLR2

6.96e-05764234995099
Pubmed

TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.

EFNA3 PLCG1 NRP1

9.09e-054764335462405
Pubmed

Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice.

FASN IGF2R GDF9

9.09e-054764332892421
Pubmed

Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting.

IGF2R ALPL

9.27e-05864215215868
Pubmed

Neuregulin repellent signaling via ErbB4 restricts GABAergic interneurons to migratory paths from ganglionic eminence to cortical destinations.

RELN ERBB4

9.27e-05864222376909
Pubmed

The semaphorin 3A receptor may directly regulate the activity of small GTPases.

FES NRP1

9.27e-05864211108845
Pubmed

Expression of the hyaluronan receptor LYVE-1 is not restricted to the lymphatic vasculature; LYVE-1 is also expressed on embryonic blood vessels.

LYVE1 NRP1

9.27e-05864218570254
Pubmed

Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies.

PCYOX1L MFGE8 IGF2R RBM27 ALPP

9.76e-0524964530097533
Pubmed

Tissue-specific venous expression of the EPH family receptor EphB1 in the skin vasculature.

LYVE1 NRP1

1.19e-04964223649798
Pubmed

Refuting the hypothesis that semaphorin-3f/neuropilin-2 exclude blood vessels from the cap mesenchyme in the developing kidney.

LYVE1 NRP1

1.19e-04964228929539
Pubmed

DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons.

RELN ERBB4 NRP1

1.23e-045264337566909
Pubmed

Mice lacking the giant protocadherin mFAT1 exhibit renal slit junction abnormalities and a partially penetrant cyclopia and anophthalmia phenotype.

DSC2 DSC3

1.49e-041064212724416
Pubmed

Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons.

RELN PLCG1

1.49e-041064215062102
Pubmed

Expression of tyrosine kinase gene in mouse thymic stromal cells.

FER FES

1.49e-04106428943574
Pubmed

CISH constrains the tuft-ILC2 circuit to set epithelial and immune tone.

POU2F3 CRLF2

1.49e-041064234290377
Pubmed

Fetal liver endothelium regulates the seeding of tissue-resident macrophages.

LYVE1 NRP1

1.81e-041164227732581
Pubmed

Evidence for new homotypic and heterotypic interactions between transmembrane helices of proteins involved in receptor tyrosine kinase and neuropilin signaling.

ERBB4 NRP1

1.81e-041164225315821
Pubmed

Defining desmosomal plakophilin-3 interactions.

DSC2 DSC3

2.17e-041264212707304
Pubmed

Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules.

ERBB4 NRP1

2.17e-041264215457507
Pubmed

TNAP limits TGF-β-dependent cardiac and skeletal muscle fibrosis by inactivating the SMAD2/3 transcription factors.

ALPL ALPP

2.17e-041264231289197
Pubmed

ErbB4 in Laminated Brain Structures: A Neurodevelopmental Approach to Schizophrenia.

RELN ERBB4

2.17e-041264226733804
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

CNTNAP3B PCYOX1L IGF2R DSC3

2.43e-0416464432409323
Pubmed

A type 2 immune circuit in the stomach controls mammalian adaptation to dietary chitin.

POU2F3 CRLF2

2.57e-041364237676935
Pubmed

HOXA13 Is essential for placental vascular patterning and labyrinth endothelial specification.

LYVE1 NRP1

2.57e-041364218483557
Pubmed

CD4+ T helper 2 cells suppress breast cancer by inducing terminal differentiation.

CSF2RB CRLF2

2.57e-041364235657353
Pubmed

Assessment of splice variant-specific functions of desmocollin 1 in the skin.

DSC2 DSC3

2.57e-041364214673151
Pubmed

Sall1 regulates mitral cell development and olfactory nerve extension in the developing olfactory bulb.

RELN NRP1

2.57e-041364218024993
Pubmed

Plexin signaling via off-track and rho family GTPases.

FES NRP1

2.57e-041364211604131
Pubmed

Tag1 deficiency results in olfactory dysfunction through impaired migration of mitral cells.

RELN NRP1

2.57e-041364226525675
Pubmed

Ephrin signalling controls brain size by regulating apoptosis of neural progenitors.

RELN EFNA3

2.99e-041464215902206
Pubmed

Smooth muscle-endothelial cell communication activates Reelin signaling and regulates lymphatic vessel formation.

LYVE1 RELN

2.99e-041464222665518
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

IGSF8 IRGM FASN IGF2R DSC2 COPB2 RPS19 COQ3 ALPL NRP1

3.01e-041451641030550785
Pubmed

Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells.

ERBB4 NRP1

3.45e-041564218356247
Pubmed

Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling.

RELN EFNA3

3.45e-041564219759535
Pubmed

The protocadherin gene Celsr3 is required for interneuron migration in the mouse forebrain.

ERBB4 NRP1

3.45e-041564219332558
Pubmed

Desmosomal localization of beta-catenin in the skin of plakoglobin null-mutant mice.

DSC2 DSC3

3.45e-04156429847250
Pubmed

Antagonist Xist and Tsix co-transcription during mouse oogenesis and maternal Xist expression during pre-implantation development calls into question the nature of the maternal imprint on the X chromosome.

IGF2R GDF9

3.45e-041564226267271
Pubmed

Vascular-Derived Vegfa Promotes Cortical Interneuron Migration and Proximity to the Vasculature in the Developing Forebrain.

RELN NRP1

3.45e-041564229901792
Pubmed

Desmocollin 3 is required for pre-implantation development of the mouse embryo.

DSC2 DSC3

3.93e-041664216418220
Pubmed

IRF6 and AP2A Interaction Regulates Epidermal Development.

DSC2 DSC3

3.93e-041664229913133
Pubmed

RPGRIP1L is required for stabilizing epidermal keratinocyte adhesion through regulating desmoglein endocytosis.

DSC2 DSC3

3.93e-041664230689641
Pubmed

Stem cell factor induces phosphatidylinositol 3'-kinase-dependent Lyn/Tec/Dok-1 complex formation in hematopoietic cells.

FES PLCG1

3.93e-041664211071635
Pubmed

Tbr2-positive intermediate (basal) neuronal progenitors safeguard cerebral cortex expansion by controlling amplification of pallial glutamatergic neurons and attraction of subpallial GABAergic interneurons.

RELN ERBB4

3.93e-041664220713522
InteractionNDST4 interactions

NDST3 EED IGF2R

1.69e-068643int:NDST4
InteractionFBXO6 interactions

IGSF8 CNTNAP3B PCYOX1L FASN IGF2R DSC3 KREMEN2 COPB2 ALPL ALPP CDC45

1.43e-057176411int:FBXO6
CytobandEnsembl 112 genes in cytogenetic band chr18q12

C18orf21 DSC2 DSC3

4.26e-04104643chr18q12
Cytoband18q12.1

DSC2 DSC3

6.08e-042664218q12.1
Cytoband17q25

FASN JMJD6

1.37e-033964217q25
Cytoband3q23

TRIM42 COPB2

1.74e-03446423q23
CytobandEnsembl 112 genes in cytogenetic band chr2q34

KANSL1L ERBB4

1.82e-0345642chr2q34
Cytoband5q32

PCYOX1L RBM27

2.61e-03546425q32
CytobandEnsembl 112 genes in cytogenetic band chr3q23

TRIM42 COPB2

3.54e-0363642chr3q23
Cytoband11q23.3

TRIM29 POU2F3

5.37e-037864211q23.3
CytobandEnsembl 112 genes in cytogenetic band chr5q32

PCYOX1L RBM27

5.64e-0380642chr5q32
GeneFamilyAlkaline phosphatases

ALPL ALPP

3.15e-0544221072
GeneFamilyFibronectin type III domain containing

FNDC7 SDK2 CSF2RB TRIM42 CRLF2

3.33e-05160425555
GeneFamilyDesmosomal cadherins

DSC2 DSC3

1.10e-0474221188
GeneFamilyPhospholipases

PLB1 PLA2G4C PLCG1

1.26e-0442423467
GeneFamilyRho GTPase activating proteins|F-BAR domain containing

FER FES

1.29e-03234221288
GeneFamilySH2 domain containing

FER FES PLCG1

1.66e-03101423741
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

ARL5B ARL5A

2.35e-0331422357
GeneFamilyZinc fingers CCCH-type

RBM27 ZC3H13

2.99e-033542273
GeneFamilyADAM metallopeptidase domain containing|CD molecules

IGSF8 IGF2R CSF2RB NRP1

1.29e-02394424471
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM42 TRIM29

2.05e-029542259
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NDST3 ERBB4 DISP3 IGSF11 MRAP2 HCRTR2

1.12e-071596460dccc4275b9b4f8554dd556da7218e130bff8fd1
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC|lymph-node_spleen / Manually curated celltypes from each tissue

RELN CSF2RB DSC2 TMEM176A TRIM29 CRLF2

1.78e-071726461b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCellsevere_influenza-Neutrophil|World / disease group, cell group and cell class (v2)

NDST3 CNTNAP3B CSF2RB DSC2 CNTNAP3 ALPL

1.91e-07174646f9f07436b7d3f190800cd85d229f007032f391e1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B SDK2 CNTNAP3 GALNT16 HCRTR2 NRP1

1.98e-0717564690e29945aa861082c94bb4f331161adc3a6ef899
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B SDK2 CNTNAP3 GALNT16 HCRTR2 NRP1

2.04e-07176646e4b21fd6a5e0c5950f27c3e1868318e48330ae5e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B SDK2 CNTNAP3 GALNT16 HCRTR2 NRP1

2.11e-071776464c069f0d044a96118090b85ca592a21d6b5d9399
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B SDK2 CNTNAP3 GALNT16 HCRTR2 NRP1

2.18e-07178646431e7557b8e8764e16e9e48368ce6bfa3c61561a
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B SDK2 CNTNAP3 GALNT16 HCRTR2 NRP1

2.26e-07179646f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B SDK2 CNTNAP3 GALNT16 HCRTR2 NRP1

2.57e-0718364665f2a5895d166189a095cf7ea9dda171f0419b08
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lhx6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ERBB4 DSC2 DISP3 IGSF11 HCRTR2

8.34e-07120645a4e3f9a83bc52ccc75bcd64b1be4e2c5441f6d1a
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN ERBB4 TMEM176A IGSF11 HCRTR2

1.29e-061316459ca209a8652aae603c4a867ea06b06ac51e7d189
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CNTNAP3B IGF2R CSF2RB CNTNAP3 ALPL

1.92e-06142645191a13bba143ecdfc2bfd797c3ac191481388298
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CNTNAP3B IGF2R CSF2RB CNTNAP3 ALPL

1.98e-06143645b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCellfacs-Pancreas-Exocrine-3m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 FNDC7 CSF2RB FOLR2 FES

2.35e-06148645bbf4933582b50b3412c805de5ed137107c996236
ToppCellfacs-Pancreas-Exocrine-3m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 FNDC7 CSF2RB FOLR2 FES

2.35e-061486456543860e3207a7de92a35bb6004be51287582f7a
ToppCellfacs-Pancreas-Exocrine-3m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 FNDC7 CSF2RB FOLR2 FES

2.35e-0614864579e376503a3f9504a1ec5af4a60a09cc80e19059
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Serpinf1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC9A4 ERBB4 CNTNAP3 IGSF11 HCRTR2

2.43e-061496455293c50b3fb41b1edaf9a97354899bd13770078c
ToppCellfacs-Heart-LV-24m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RB FOLR2 TMEM176A TRIM29 CRLF2

3.65e-061626455dfdb4e227e5d7d72dbe8fe032791fddb0be064d
ToppCellfacs-Heart-LV-24m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RB FOLR2 TMEM176A TRIM29 CRLF2

3.65e-061626457f26135b884144473bbccaf3881c8cf2ba4fa05a
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN ERBB4 DISP3 IGSF11 HCRTR2

3.76e-061636458d17f44faf0549fe71a9a45f811f50d767275414
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SDK2 CNTNAP3 GALNT16 HCRTR2 NRP1

4.36e-061686457abaddbcc55e44653d54aa15464266aa6bd5c9d2
ToppCell3'_v3-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

LYVE1 ERBB4 FOLR2 TMEM176A NRP1

4.49e-06169645241644823e6f949aaf4c671d4579721d7ef6b0e5
ToppCellInfluenza_Severe-Neutrophil|World / Disease group and Cell class

NDST3 CNTNAP3B CSF2RB CNTNAP3 ALPL

4.49e-061696456e8e2580e19c96bcf7fa6a6d8c183df65f428396
ToppCellsevere_influenza-Neutrophil|severe_influenza / disease group, cell group and cell class (v2)

NDST3 CNTNAP3B CSF2RB CNTNAP3 ALPL

5.03e-06173645615e266419b9f06e964eff73cb466f05451ba0dd
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B SDK2 CNTNAP3 GALNT16 NRP1

5.63e-06177645bde307e67ad8e48a5ff4c0827015f4688f6b3e46
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DSC2 DSC3 PORCN TRIM29 ALPL

5.78e-06178645b89c4d015b44bf538aa39969ef8778877c8023f1
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DSC2 DSC3 PORCN TRIM29 ALPL

5.78e-06178645fb8f8d95f6b08378fb42c4076ee040276faa296f
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3B LYVE1 RELN PLA2G4C CNTNAP3

5.94e-06179645ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B SDK2 CNTNAP3 GALNT16 NRP1

5.94e-061796457954c0026754ab869b88ab7feb13c2f27d6e272d
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3B LYVE1 RELN PLA2G4C CNTNAP3

5.94e-0617964535fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-monocytoid_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LYVE1 FOLR2 CNTNAP3 TMEM176A NRP1

6.11e-06180645ba4c1fb55e8f1095bea6968417fefcf5f700926b
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B SDK2 CNTNAP3 GALNT16 NRP1

6.11e-06180645b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B SDK2 CNTNAP3 GALNT16 NRP1

6.27e-0618164508f44323bf71b6004a921bbc969c954c75feeb66
ToppCell18-Airway-Epithelial-Submucosal_gland_basal|Airway / Age, Tissue, Lineage and Cell class

EFNA3 DSC3 KREMEN2 TRIM29 POU2F3

6.27e-0618164533938e6521712058312879f84f4ae381c2bfc379
ToppCellHippocampus-Neuronal-Inhibitory|Hippocampus / BrainAtlas - Mouse McCarroll V32

RELN ERBB4 CNTNAP3 MRAP2 ARL5A

6.44e-06182645b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCell390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

LYVE1 FOLR2 FES TMEM176A

6.59e-0684644013cf97d08d0adb3697cf2a146ff5ca13c676f64
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Basal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSC2 DSC3 PORCN TRIM29 ALPL

6.62e-06183645ecac1cfaff7553a60305b34d6cede6973ffb5430
ToppCellfacs-Lung-EPCAM-3m-Epithelial-respiratory_basal_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSC2 DSC3 PORCN TRIM29 ALPL

6.62e-06183645f6ebfd7f61e912f92bd07313cc213a171747ac03
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

SDK2 DSC3 IGSF11 MRAP2 TRIM29

6.79e-06184645ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CNTNAP3B LYVE1 RELN PLA2G4C CNTNAP3

6.97e-06185645f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3B LYVE1 RELN PLA2G4C CNTNAP3

6.97e-061856453be9e05b929ac4d956b1d53284072f668a6c1959
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3B LYVE1 RELN PLA2G4C CNTNAP3

6.97e-06185645c3dd64a726cb8a1fe048683c266b7532a714a52e
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-lymphatic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3B LYVE1 RELN PLA2G4C CNTNAP3

7.16e-061866455d94e6dd2c92e0c46badeb1e6eb54b69af855a66
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3B LYVE1 RELN PLA2G4C CNTNAP3

7.16e-061866451da52e13096dfe4eb08bd0e7461cb3809b3b3deb
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma|TCGA-Lung / Sample_Type by Project: Shred V9

DSC3 IGSF11 COQ3 TRIM29 CDC45

7.74e-06189645aa4f7d7a5196e5ae481ebc2549de8e3f0ef6e6be
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3B LYVE1 CSF2RB CNTNAP3 MRAP2

8.56e-0619364584d1c1b7d3a1cb80f175527e3c89a2c3da7657f7
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|367C / Donor, Lineage, Cell class and subclass (all cells)

LYVE1 DSC2 FOLR2 TMEM176A NRP1

8.78e-06194645e3688f4252aae5f849f025d7f453ff4c0c14590b
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LYVE1 DSC2 FOLR2 TMEM176A NRP1

8.78e-0619464548c37251518f96524807b5bd1bbc2820637666ad
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LYVE1 DSC2 FOLR2 TMEM176A NRP1

8.78e-061946457b6a34d1f8922b71dcc931421666c1822cec8345
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LYVE1 DSC2 FOLR2 TMEM176A NRP1

8.78e-06194645435406ebe626c702f7d5a99a3d68ee85aa09be95
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DSC2 CNTNAP3 CSMD2 GALNT16 ALPL

9.00e-06195645d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DSC2 CNTNAP3 CSMD2 GALNT16 ALPL

9.00e-0619564519853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3B LYVE1 CNTNAP3 TMEM176A MRAP2

9.00e-06195645ca2cf2c10db1ad17aa0a2e30aa7079a7ad751ea6
ToppCellmLN-(5)_Dendritic_cell|mLN / shred on region, Cell_type, and subtype

CSF2RB DSC2 TMEM176A CRLF2 NRP1

9.93e-061996454feecf533e29a1a558f1018a2e8f7bfa7b9d3864
ToppCellmLN-Dendritic_cell|mLN / Region, Cell class and subclass

CSF2RB DSC2 TMEM176A CRLF2 NRP1

9.93e-06199645597412beae1324b9c43ca2bb96c4cb645c19f3e9
ToppCellBronchus_Control_(B.)-Immune-TX-MoAM-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

LYVE1 DSC2 FOLR2 TMEM176A NRP1

9.93e-06199645fb63885273d906a85fef178d859d20a311eb8a72
ToppCellNeuronal-Excitatory-eD(FEZF2)-ABO-|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3B SDK2 CNTNAP3 HCRTR2 NRP1

1.02e-05200645e3051dcf9b5c8e4dc71a8080b7a7aafea46f2b2b
ToppCellNeuronal-Excitatory-eD(FEZF2)-ABO--|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3B SDK2 CNTNAP3 HCRTR2 NRP1

1.02e-052006451ce9599cc9d8158e8842ca56f35fa7809c234849
ToppCellSigmoid-Macrophage|Sigmoid / Region, Cell class and subclass

LYVE1 DSC2 FOLR2 TMEM176A NRP1

1.02e-05200645b07ac0ff3b8530e99094678fed80f35949cafac8
ToppCellNeuronal-Excitatory-eD(FEZF2)-ABO---L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3B SDK2 CNTNAP3 HCRTR2 NRP1

1.02e-052006457b845aabfbdfe893acc9334a5707833761bed60b
ToppCellNeuronal-Excitatory-eD(FEZF2)-ABO|Neuronal / cells hierarchy compared to all cells using T-Statistic

CNTNAP3B SDK2 CNTNAP3 HCRTR2 NRP1

1.02e-052006450638273fc0910f47fe7a0b6d9a8639b0e9976d13
ToppCellSigmoid-(6)_Macrophage|Sigmoid / shred on region, Cell_type, and subtype

LYVE1 DSC2 FOLR2 TMEM176A NRP1

1.02e-052006459e10cca4429de2c4c8c3c6cf2c9e28637a095be9
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lhx6|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ERBB4 CNTNAP3 IGSF11 HCRTR2

2.45e-051176440602bbad908cb28c5093b74d717da5f2af577943
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN SLC9A4 ERBB4 IGSF11

3.07e-05124644690595d710b57b7cff8029a3bb06a8dd7e3c03c1
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN ERBB4 DISP3 IGSF11

3.70e-051306448bd038b0423960ffdc6c8b128c46a55386f9c58c
ToppCellfacs-Marrow-B-cells-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RB CNTNAP3 DISP3 NRP1

5.36e-051436446df16bf0324661cd9707df69cb39f4b5498d6d49
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB4 ERBB4 CFAP61 GDF9

5.97e-051476442885978bcfc5623967c0c1204dadf5c78c74a082
ToppCellfrontal_cortex-Non-neuronal-macrophage-Macrophage-PVM_Mrc1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LYVE1 CSF2RB FOLR2 FES

6.13e-05148644d3ea907f8f408e9bb97ed223a3089e403e35f911
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP3B IRGM PORCN CDC45

6.13e-0514864418cfecd6ae20edb74f5d44ba759909df356acf3a
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN ERBB4 DISP3 IGSF11

6.13e-051486445e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCellfacs-Skin-nan-18m-Myeloid-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 CSF2RB FOLR2 FES

6.29e-0514964423a1b95c12f2e3708dc003e13fab423e89821f11
ToppCellfacs-Skin-nan-18m-Myeloid-macrophage|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 CSF2RB FOLR2 FES

6.29e-05149644c53a3226adc8fd0eaaa842b6a96442287580cbe0
ToppCellfacs-Skin-nan-18m-Myeloid|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 CSF2RB FOLR2 FES

6.29e-05149644bb18a18b891af85849b9658d774053f839c9a8e1
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN ERBB4 DISP3 IGSF11

6.80e-05152644fed80b467ec9e30c7f98bed6cc4f8c583b715e9e
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Myeloid-macrophage|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 CSF2RB FOLR2 CRLF2

6.97e-051536444b999892fb797e9f0d391630094f466463299d57
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Myeloid-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 CSF2RB FOLR2 CRLF2

6.97e-05153644e426db29e4ba83e7930dc88c74fc975b177c9540
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Myeloid|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A4 CSF2RB FOLR2 CRLF2

6.97e-05153644668eacd76aad6054bd7d57e3af0b122c2443465f
ToppCelldroplet-Fat-SCAT-30m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYVE1 ERBB4 FOLR2 TMEM176A

7.15e-0515464473de626b210ec5482ba89a65e784c1e77ff2894e
ToppCelldroplet-Fat-SCAT-30m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYVE1 ERBB4 FOLR2 TMEM176A

7.15e-0515464456fe9953e58f71626d3ddf63d340ed35dfc4ce9f
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RELN ERBB4 DISP3 HCRTR2

7.33e-05155644105d59d8a1bb8cb37eef2c1767d737b2108ac7c5
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN ERBB4 DISP3 IGSF11

7.70e-05157644516903469756c5fabfdf56d7bd59b3bdd7b44e39
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-lymphocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G4C CSF2RB FES GDF9

8.09e-051596443bab00f8fb7d9232538e50f83dd0fd70ddd16819
ToppCellPND07-28-samps-Myeloid-Macrophage-macrophage-B|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SLC9A4 CSF2RB DDHD1 TRIM29

8.29e-05160644694bf1f1952bd8ab444819f533da24fa2b73f701
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-CD45|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G4C CSF2RB FES GDF9

8.29e-051606445bec867def73fa8531f8dad611679f4b44f573bd
ToppCelldroplet-Fat-SCAT-30m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYVE1 ERBB4 FOLR2 TMEM176A

8.29e-0516064461eefe84c8e30d8a3812f5b48d26ed01739aa1ce
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Hippocampus / BrainAtlas - Mouse McCarroll V32

RELN ERBB4 CNTNAP3 ARL5A

8.49e-05161644b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCellInfluenza_Severe-Neutrophil|Influenza_Severe / Disease group and Cell class

NDST3 CNTNAP3B CNTNAP3 ALPL

8.49e-0516164498c95b1b85d5427415af2ca8fb14849e97f6e8b5
ToppCellTCGA-Kidney-Solid_Tissue_Normal-Kidney-Kidney_normal_tissue|TCGA-Kidney / Sample_Type by Project: Shred V9

NDST3 SLC9A4 ERBB4 HCRTR2

8.70e-05162644a0367e9af78e4699b9d89d3e0597589e644f844c
ToppCellTCGA-Kidney-Solid_Tissue_Normal-Kidney|TCGA-Kidney / Sample_Type by Project: Shred V9

NDST3 SLC9A4 ERBB4 HCRTR2

8.70e-05162644d007ec42d6458431f6c490df61de7a9caef857f0
ToppCellTCGA-Kidney-Solid_Tissue_Normal|TCGA-Kidney / Sample_Type by Project: Shred V9

NDST3 SLC9A4 ERBB4 HCRTR2

8.70e-0516264465549ffdbfe8619693345db78e6ddbdde7b742c9
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DISP3 IGSF11 MRAP2 HCRTR2

8.91e-05163644bba830a302919c8b33f914a8839877fc21dd28a0
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN ERBB4 DISP3 IGSF11

9.12e-0516464408819970174a3eb4eee8e1e675075828665b845e
ToppCellBasal_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DSC2 KREMEN2 TRIM29 SOAT2

9.12e-0516464485487a303194f5244956ec1ca2d1758d38117f41
ToppCellMonocytes-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

NDST3 KREMEN2 FES TMEM176A

9.34e-0516564483d06210a50073fbb7082eabd8298dd355c40416
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells-ectodermal/neuroectodermal-like_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

DSC3 KREMEN2 RPS19 TRIM29

9.56e-05166644d7e49416426a62801ea1062d7aaf55ea622ae118
ToppCellDendritic_Cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

LYVE1 PLB1 FOLR2 TMEM176A

9.56e-05166644fbeb74b98b58085de323f744b18d4a8f7b22d5d4
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D122|Adult / Lineage, Cell type, age group and donor

LYVE1 PLB1 FOLR2 NRP1

9.56e-05166644be284e2e596390f05305c7bcfc316f87b963fc0b
ToppCellfacs-Heart-LA-24m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYVE1 CSF2RB FOLR2 TMEM176A

9.56e-051666442c931d593e189127c31adaf36a3df81d8287bb53
ToppCellfacs-Heart-LA-24m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYVE1 CSF2RB FOLR2 TMEM176A

9.56e-051666449e7a9cb7beeb7015fcaa476a4902883dee99e8c0
ToppCellfacs-Heart-LA-24m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYVE1 CSF2RB FOLR2 TMEM176A

9.56e-051666442a3c396deb068066b8c2f85ddd2fa52629776bcd
ComputationalIntermediate filaments.

FASN DSC3 MRAP2 TRIM29

1.35e-0475384MODULE_154
ComputationalIntermediate filaments and keratins.

FASN DSC3 MRAP2 TRIM29

1.73e-0480384MODULE_357
ComputationalGenes in the cancer module 297.

FASN DSC3 MRAP2 TRIM29

1.73e-0480384MODULE_297
ComputationalGenes in the cancer module 20.

EFNA3 FES PLCG1 RABGGTA

2.00e-0483384MODULE_20
ComputationalNeighborhood of LTK

FES RABGGTA HTT

5.57e-0446383GCM_LTK
ComputationalGenes in the cancer module 85.

ERBB4 CSF2RB NRP1

7.55e-0451383MODULE_85
ComputationalGenes in the cancer module 199.

ERBB4 CSF2RB NRP1

1.05e-0357383MODULE_199
DrugAC1L48S9

LYVE1 ALPL ALPP

4.58e-0612643CID000152644
DrugMethylnitronitrosoguanidine

RELN FASN ERBB4 JMJD6 FES ALPL NRP1

9.43e-06265647ctd:D008769
DrugAmbroxol hydrochloride [23828-92-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A

MFGE8 DSC2 JMJD6 TRIM29 SOAT2 HCRTR2

1.87e-051966463238_UP
DrugOrphenadrine hydrochloride [341-69-5]; Up 200; 13uM; MCF7; HT_HG-U133A

RELN DSC2 FOLR2 KREMEN2 TMEM176A SOAT2

1.92e-051976462318_UP
DrugScopolamin-N-oxide hydrobromide [6106-81-6]; Up 200; 10uM; MCF7; HT_HG-U133A

LYVE1 MFGE8 PLA2G4C DSC3 ZC3H13 KREMEN2

2.03e-051996465436_UP
Drug5-hydroxycytidine

ALPL ALPP

2.33e-053642CID000198207
DrugAlphostatin

ALPL ALPP

2.33e-053642CID000174788
DrugG 3012

MFGE8 RELN EFNA3 NRP1 CDC45

3.52e-05132645CID000120739
Drug3-indoxyl phosphate

ALPL ALPP

4.65e-054642CID000026292
Drugp-bromotetramisole

ALPL ALPP

4.65e-054642CID000005121
Drugammediol

ALPL ALPP

4.65e-054642CID000001531
Drugethylethanolamine

ALPL ALPP

4.65e-054642CID000008072
DrugFast Blue RR

ALPL ALPP

7.74e-055642CID000093116
DrugSMR 6

ALPL ALPP

7.74e-055642CID006439864
Drugranelic acid

ALPL ALPP

7.74e-055642CID003052774
Drugmitomycin phosphate

ALPL ALPP

7.74e-055642CID000130219
Drugbutylparaben

RELN FASN ERBB4 IGF2R ALPL

8.03e-05157645ctd:C038091
Diseaseout at first protein homolog measurement

TRIM29 POU2F3

1.39e-053642EFO_0801862
Diseasearrhythmogenic right ventricular cardiomyopathy (implicated_via_orthology)

DSC2 DSC3

4.61e-055642DOID:0050431 (implicated_via_orthology)
Diseasedesmocollin-2 measurement

DSC2 DSC3

4.61e-055642EFO_0021936
Diseasehepatocellular carcinoma (is_implicated_in)

ERBB4 IGF2R FES PLCG1 SOAT2

4.67e-05181645DOID:684 (is_implicated_in)
Diseaseresponse to tenofovir, creatinine clearance measurement

ZC3H13 IGSF11 MRAP2 NRP1

1.05e-04112644EFO_0007934, EFO_0009279
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP3B CNTNAP3

1.29e-048642DOID:0060308 (implicated_via_orthology)
Diseaseinterleukin 25 measurement

TRIM29 POU2F3

1.65e-049642EFO_0008182
Diseaseurolithiasis

HCRTR2 ALPL ALPP

3.52e-0463643MONDO_0024647
Diseasemigraine disorder, endometriosis

ERBB4 EXOC2 NRP1

5.43e-0473643EFO_0001065, MONDO_0005277
DiseaseHuntington Disease

RELN HTT

6.17e-0417642C0020179
Diseasesusceptibility to scarlet fever measurement

PLB1 SDK2 FRYL

6.84e-0479643EFO_0008409
Diseaselaryngeal squamous cell carcinoma (is_marker_for)

ERBB4 PLCG1

7.73e-0419642DOID:2876 (is_marker_for)
Diseasesleep duration, low density lipoprotein cholesterol measurement

IGF2R PLCG1 HTT

1.03e-0391643EFO_0004611, EFO_0005271
DiseaseBreast Carcinoma

MFGE8 FASN ERBB4 DSC3 JMJD6 GALNT16

1.09e-03538646C0678222
Diseasediffuse plaque measurement

NDST3 RELN ERBB4 SDK2 EXOC2 TRIM29 HCRTR2

1.25e-03758647EFO_0010699
Diseasepallidum volume

FER ALPL

1.35e-0325642EFO_0006933
DiseaseBell's palsy

ERBB4 EFNA3 RBM27

1.43e-03102643EFO_0007167
Diseaseacute myocardial infarction (biomarker_via_orthology)

DSC2 PLCG1

1.69e-0328642DOID:9408 (biomarker_via_orthology)
Diseasemelanoma

FASN ERBB4 ARL5B JMJD6

2.08e-03248644C0025202

Protein segments in the cluster

PeptideGeneStartEntry
TDNSNLCYYHTINWT

ERBB4

461

Q15303
TKFSNRYYSNEWTHS

CFAP61

981

Q8NHU2
RYYSNEWTHSNFSSK

CFAP61

986

Q8NHU2
WDYSRAYVSANTQTH

DISP3

256

Q9P2K9
FWNSASFNTETSYLH

CNTNAP3

791

Q9BZ76
ESLRSSWNTYYTNTE

ARL5A

71

Q9Y689
ESLRSSWNTYYSNTE

ARL5B

71

Q96KC2
SNSVYLRWSSDHAYN

CSMD2

2441

Q7Z408
WHSSTYRLESTLNYG

COPB2

256

P35606
WHWSENTSLNYAAYA

COQ3

316

Q9NZJ6
VDNCRYTYSEWHSFT

DSC2

816

Q02487
FYYLWQDNRAHAASS

GALNT16

21

Q8N428
DPSDRAYSWYQHQRS

NDST3

696

O95803
AHHSENTTESWSNYY

RBM27

246

Q9P2N5
NTTESWSNYYNNHSS

RBM27

251

Q9P2N5
WSNYYNNHSSSNSFG

RBM27

256

Q9P2N5
ASTWSSYEHNSESYL

KANSL1L

606

A0AUZ9
WTRHNYYESFSLSPA

JMJD6

26

Q6NYC1
SRQFAAYCYNSSDTW

LYVE1

121

Q9Y5Y7
VASYKVAYSNDSANW

MFGE8

316

Q08431
IYWQASRGSANYSTD

FNDC7

646

Q5VTL7
ASYFSSHFSNVVLWD

IRGM

76

A1A4Y4
FRSYYSVQTAEWQAH

PCYOX1L

411

Q8NBM8
SAAWYLIENHSNTSF

EXOC2

166

Q96KP1
YSTHTYSRDCSNWIN

FRYL

2151

O94915
LFWDQTQQHSYSSAS

KREMEN2

61

Q8NCW0
NFYTCAWTYDSNTSH

EED

146

O75530
WNASKYSRTNLTFHY

CRLF2

46

Q9HC73
NSSGSWYRWNHSTYL

POU2F3

421

Q9UKI9
STVYSSENYSGWNRI

RELN

621

P78509
ATRFRWSQSYYTAQD

RELN

1006

P78509
QYSTNWSAERSRLNY

NRP1

296

O14786
TYAHTVNRNWYSDAD

ALPP

181

P05187
AAYAHSADRDWYSDN

ALPL

176

P05186
WLRAYESAVSFHFSN

PORCN

241

Q9H237
FTFSHWLVYANSAAN

HCRTR2

346

O43614
AARSENYSLTDFWAY

PLA2G4C

126

Q9UP65
YQHWSLHDSLCNTSY

CDC45

281

O75419
SICQHSRRTQYFYSW

HTT

276

P42858
LTSSNAYNSRYWSNN

IGSF11

311

Q5DX21
YNDYTSHITCRWADT

CSF2RB

36

P32927
QHADYSWYQAGSARS

IGSF8

551

Q969P0
VDNCRYTYSEWHSFT

DSC3

811

Q14574
YWNSSNQHLRREGYT

EFNA3

36

P52797
ALNYGRYSSESDVWS

FER

731

P16591
LWSHSYKVSNYSRGS

FOLR2

186

P14207
QYFAHSCYQNLWSSD

LAMB4

921

A4D0S4
YLNDTSAQAYHSWYS

GDF9

266

O60383
VESRYWSAVTSHTAY

DDHD1

856

Q8NEL9
QWHSSLARTSSAEYN

FASN

721

P49327
SWEEYNRTNTRVTHY

SDK2

931

Q58EX2
QARYLLWAYTSSHDD

C18orf21

21

Q32NC0
FWNSASFNTETSYLH

CNTNAP3B

791

Q96NU0
WTHLQNIASNYNVSY

PTX4

56

Q96A99
ALNYGRYSSESDVWS

FES

731

P07332
HETADCQYLFSWYTS

IGF2R

2261

P11717
NYTSRVWEYSSSIQN

TRIM29

511

Q14134
NSSSFHNWYSFNDGS

TRIM42

586

Q8IWZ5
LQFYSNLHNAETSSW

TMEM179B

156

Q7Z7N9
NWFYTRAASTARHLY

RPS19

51

P39019
YYNSACRISSSSDWN

TMEM176A

146

Q96HP8
ITRNFSNYSSWHYRS

RABGGTA

171

Q92696
STAQYASNAWFAAAS

SLC9A4

36

Q6AI14
SYQEAWNSLLASSRY

PLB1

256

Q6P1J6
SFSNYYRTWNVVVHD

SOAT2

386

O75908
TSQQSASNSDYTWEY

MRAP2

11

Q96G30
LSHYWISSSHNTYLT

PLCG1

326

P19174
HSSNSNYHDSWETRS

ZC3H13

586

Q5T200