Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

ROCK2 BICD2 KIF21B STMN4 MYH10 KIF23 MAP7D3 SYNM IQCJ-SCHIP1 PLEC KIF2C MSN

1.22e-0410996212GO:0008092
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

ROCK2 BICD2 CCDC13 STMN4 KIF23 MAP7D3 PPP1R12A SMC1A SDCCAG8 CKAP2 HYDIN CHMP2B KIF2C CCDC40 BBOF1

1.91e-097206115GO:0000226
GeneOntologyBiologicalProcessmicrotubule-based process

ROCK2 BICD2 KIF21B CCDC13 STMN4 KIF23 MAP7D3 PPP1R12A SMC1A SDCCAG8 CKAP2 HYDIN CHMP2B KIF2C CCDC40 BBOF1

4.69e-0810586116GO:0007017
GeneOntologyBiologicalProcesscell cycle process

ROCK2 ANKRD31 TAOK3 MYH10 KIF23 SFRP1 PPP1R12A SMC1A SDCCAG8 SYCP3 PIWIL2 CKAP2 PLEC ENSA ZWINT CHMP2B KIF2C

5.75e-0714416117GO:0022402
GeneOntologyBiologicalProcesscytoskeleton-dependent cytokinesis

ROCK2 MYH10 KIF23 CKAP2 PLEC CHMP2B

2.04e-06127616GO:0061640
GeneOntologyBiologicalProcesscell division

ROCK2 MYH10 KIF23 SMC1A SYCP3 CKAP2 PLEC ENSA ZWINT CHMP2B KIF2C

5.44e-066976111GO:0051301
GeneOntologyBiologicalProcessmitotic cytokinesis

ROCK2 MYH10 KIF23 CKAP2 CHMP2B

9.04e-0695615GO:0000281
GeneOntologyBiologicalProcesscytokinesis

ROCK2 MYH10 KIF23 CKAP2 PLEC CHMP2B

3.07e-05204616GO:0000910
GeneOntologyBiologicalProcessmitotic cell cycle

ROCK2 TAOK3 MYH10 KIF23 PPP1R12A SMC1A SYCP3 CKAP2 ENSA ZWINT CHMP2B KIF2C

3.49e-0510146112GO:0000278
GeneOntologyBiologicalProcessnuclear chromosome segregation

ANKRD31 KIF23 SMC1A SYCP3 ZWINT CHMP2B KIF2C

8.43e-05356617GO:0098813
GeneOntologyBiologicalProcesssupramolecular fiber organization

ROCK2 PTK2B CCDC13 STMN4 MYH10 SFRP1 MAP7D3 COLGALT2 CKAP2 PLEC KIF2C

1.01e-049576111GO:0097435
GeneOntologyBiologicalProcessorganelle assembly

PTK2B CCDC13 MYH10 KIF23 SMC1A SDCCAG8 PLEC HYDIN CHMP2B CCDC40 BBOF1 MSN

1.06e-0411386112GO:0070925
GeneOntologyBiologicalProcessregulation of organelle organization

ROCK2 BICD2 PTK2B STMN4 SFRP1 SDCCAG8 PIWIL2 IQCJ-SCHIP1 CKAP2 ZWINT CHMP2B VAT1 MSN

1.23e-0413426113GO:0033043
GeneOntologyBiologicalProcessnuclear division

ANKRD31 KIF23 SMC1A SYCP3 PIWIL2 ZWINT CHMP2B KIF2C

1.27e-04512618GO:0000280
GeneOntologyBiologicalProcesspostsynaptic cytoskeleton organization

ROCK2 MYH10 KIF2C

1.51e-0435613GO:0099188
GeneOntologyBiologicalProcessmitotic cell cycle process

ROCK2 TAOK3 MYH10 KIF23 SMC1A CKAP2 ENSA ZWINT CHMP2B KIF2C

1.86e-048546110GO:1903047
GeneOntologyBiologicalProcessregulation of microtubule-based process

ROCK2 BICD2 STMN4 CKAP2 CHMP2B CCDC40

2.25e-04293616GO:0032886
GeneOntologyBiologicalProcessorganelle fission

ANKRD31 KIF23 SMC1A SYCP3 PIWIL2 ZWINT CHMP2B KIF2C

2.66e-04571618GO:0048285
GeneOntologyBiologicalProcessregulation of cytoskeleton organization

ROCK2 BICD2 PTK2B STMN4 SFRP1 IQCJ-SCHIP1 CKAP2 CHMP2B

2.92e-04579618GO:0051493
GeneOntologyBiologicalProcesscell-substrate junction assembly

ROCK2 PTK2B SFRP1 PLEC

2.95e-04108614GO:0007044
GeneOntologyBiologicalProcessregulation of meiosis I

PIWIL2 ZWINT

3.06e-049612GO:0060631
GeneOntologyBiologicalProcessmulti-pass transmembrane protein insertion into ER membrane

CCDC47 TMCO1

3.06e-049612GO:0160063
GeneOntologyBiologicalProcesscell-substrate junction organization

ROCK2 PTK2B SFRP1 PLEC

3.75e-04115614GO:0150115
GeneOntologyBiologicalProcessregulation of protein localization to early endosome

ROCK2 MSN

3.81e-0410612GO:1902965
GeneOntologyBiologicalProcesspositive regulation of protein localization to early endosome

ROCK2 MSN

3.81e-0410612GO:1902966
GeneOntologyBiologicalProcessmitotic sister chromatid segregation

KIF23 SMC1A ZWINT CHMP2B KIF2C

4.08e-04212615GO:0000070
GeneOntologyBiologicalProcesschromosome segregation

ANKRD31 KIF23 SMC1A SYCP3 ZWINT CHMP2B KIF2C

4.32e-04465617GO:0007059
GeneOntologyBiologicalProcessresponse to testosterone

ROCK2 HOXA9 MSN

5.19e-0453613GO:0033574
GeneOntologyBiologicalProcessmicrotubule-based movement

BICD2 KIF21B KIF23 HYDIN KIF2C CCDC40 BBOF1

6.11e-04493617GO:0007018
GeneOntologyBiologicalProcesscortical cytoskeleton organization

ROCK2 PTK2B PLEC

6.43e-0457613GO:0030865
GeneOntologyBiologicalProcesscellular response to testosterone stimulus

ROCK2 MSN

6.57e-0413612GO:0071394
GeneOntologyBiologicalProcessmeiotic chromosome separation

SYCP3 ZWINT

6.57e-0413612GO:0051307
GeneOntologyBiologicalProcessendothelin receptor signaling pathway

PTK2B PLCB4

6.57e-0413612GO:0086100
GeneOntologyBiologicalProcessestablishment of endothelial barrier

ROCK2 PPP1R12A MSN

6.76e-0458613GO:0061028
GeneOntologyBiologicalProcessactomyosin structure organization

ROCK2 PTK2B MYH10 SFRP1 PLEC

7.03e-04239615GO:0031032
GeneOntologyBiologicalProcesspositive regulation of protein localization to endosome

ROCK2 MSN

7.65e-0414612GO:1905668
GeneOntologyBiologicalProcessregulation of cell cycle process

ROCK2 ANKRD31 TAOK3 KIF23 SFRP1 PIWIL2 ZWINT CHMP2B KIF2C

7.98e-04845619GO:0010564
GeneOntologyBiologicalProcessregulation of protein localization to endosome

ROCK2 MSN

8.81e-0415612GO:1905666
GeneOntologyBiologicalProcessmeiotic sister chromatid cohesion

SMC1A SYCP3

8.81e-0415612GO:0051177
GeneOntologyBiologicalProcessER overload response

CCDC47 TMCO1

8.81e-0415612GO:0006983
GeneOntologyBiologicalProcesssister chromatid segregation

KIF23 SMC1A ZWINT CHMP2B KIF2C

9.23e-04254615GO:0000819
GeneOntologyBiologicalProcessmeiosis I

ANKRD31 SYCP3 PIWIL2 ZWINT

9.43e-04147614GO:0007127
GeneOntologyBiologicalProcessmicrotubule depolymerization

STMN4 CKAP2 KIF2C

9.86e-0466613GO:0007019
GeneOntologyBiologicalProcessprotein localization to early endosome

ROCK2 MSN

1.01e-0316612GO:1902946
GeneOntologyBiologicalProcessmeiosis I cell cycle process

ANKRD31 SYCP3 PIWIL2 ZWINT

1.15e-03155614GO:0061982
GeneOntologyBiologicalProcessepithelial cell development

ROCK2 PPP1R12A PLEC HYDIN MSN

1.19e-03269615GO:0002064
GeneOntologyCellularComponentcondensed chromosome, centromeric region

PPP1R12A SMC1A SYCP3 ZWINT CHMP2B KIF2C

2.29e-05193626GO:0000779
GeneOntologyCellularComponentspindle

ROCK2 MYH10 KIF23 MAP7D3 SMC1A CKAP2 CHMP2B KIF2C

7.28e-05471628GO:0005819
GeneOntologyCellularComponentchromosome, centromeric region

PPP1R12A SMC1A SYCP3 ZWINT CHMP2B KIF2C

1.66e-04276626GO:0000775
GeneOntologyCellularComponentkinetochore

PPP1R12A SMC1A ZWINT CHMP2B KIF2C

2.00e-04181625GO:0000776
GeneOntologyCellularComponentsarcolemma

SYNM PLEC ADCY5 RYR3 MSN

2.50e-04190625GO:0042383
GeneOntologyCellularComponentcondensed chromosome

PPP1R12A SMC1A SYCP3 ZWINT CHMP2B KIF2C

2.94e-04307626GO:0000793
GeneOntologyCellularComponentmulti-pass translocon complex

CCDC47 TMCO1

3.07e-049622GO:0160064
GeneOntologyCellularComponentmicrotubule organizing center

ROCK2 BICD2 CCDC13 KIF23 PPP1R12A SDCCAG8 CKAP2 ECPAS KIF2C BBOF1

3.46e-049196210GO:0005815
GeneOntologyCellularComponentkinesin complex

KIF21B KIF23 KIF2C

4.15e-0449623GO:0005871
GeneOntologyCellularComponentcentrosome

ROCK2 BICD2 CCDC13 KIF23 PPP1R12A SDCCAG8 CKAP2 ECPAS KIF2C

4.20e-04770629GO:0005813
GeneOntologyCellularComponentER membrane insertion complex

CCDC47 TMCO1

7.70e-0414622GO:0072379
GeneOntologyCellularComponentZ disc

SYNM PPP1R12A PLEC RYR3

1.05e-03151624GO:0030018
GeneOntologyCellularComponentlateral element

SMC1A SYCP3

1.43e-0319622GO:0000800
GeneOntologyCellularComponentI band

SYNM PPP1R12A PLEC RYR3

1.50e-03166624GO:0031674
GeneOntologyCellularComponentchromosomal region

PPP1R12A SMC1A SYCP3 ZWINT CHMP2B KIF2C

1.53e-03421626GO:0098687
GeneOntologyCellularComponentcostamere

SYNM PLEC

1.92e-0322622GO:0043034
GeneOntologyCellularComponentsupramolecular fiber

KIF21B MYH10 KIF23 SYNM PPP1R12A CKAP2 PLEC RYR3 CHMP2B KIF2C

2.31e-0311796210GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

KIF21B MYH10 KIF23 SYNM PPP1R12A CKAP2 PLEC RYR3 CHMP2B KIF2C

2.43e-0311876210GO:0099081
GeneOntologyCellularComponentpostsynapse

ROCK2 KIF21B PTK2B RPL29 MYH10 PLCB4 RGS10 CHMP2B KIF2C

2.95e-031018629GO:0098794
DomainKinesin_motor_CS

KIF21B KIF23 KIF2C

3.23e-0441613IPR019821
DomainKinesin-like_fam

KIF21B KIF23 KIF2C

3.73e-0443613IPR027640
DomainKINESIN_MOTOR_1

KIF21B KIF23 KIF2C

3.99e-0444613PS00411
Domain-

KIF21B KIF23 KIF2C

3.99e-04446133.40.850.10
DomainKinesin_motor_dom

KIF21B KIF23 KIF2C

3.99e-0444613IPR001752
DomainKinesin

KIF21B KIF23 KIF2C

3.99e-0444613PF00225
DomainKINESIN_MOTOR_2

KIF21B KIF23 KIF2C

3.99e-0444613PS50067
DomainKISc

KIF21B KIF23 KIF2C

3.99e-0444613SM00129
PathwayREACTOME_RHO_GTPASES_ACTIVATE_ROCKS

ROCK2 MYH10 PPP1R12A

2.31e-0519423M27493
PathwayREACTOME_CELL_CYCLE

KIF23 PPP1R12A SMC1A SDCCAG8 SYCP3 ENSA ZWINT CHMP2B KIF2C

1.66e-04694429M543
PathwayREACTOME_M_PHASE

KIF23 SMC1A SDCCAG8 ENSA ZWINT CHMP2B KIF2C

2.08e-04417427M27662
PathwayREACTOME_CELL_CYCLE_MITOTIC

KIF23 PPP1R12A SMC1A SDCCAG8 ENSA ZWINT CHMP2B KIF2C

2.13e-04561428M5336
PathwayPID_RHOA_PATHWAY

ROCK2 PPP1R12A MSN

3.20e-0445423M12
PathwayKEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION

ROCK2 PPP1R12A PLCB4 ADCY5

3.70e-04115424M9387
PathwayWP_PTDINS45P2_IN_CYTOKINESIS_PATHWAY

KIF23 MSN

5.61e-0412422M45558
PathwayREACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT

BICD2 KIF21B KIF23 KIF2C

6.06e-04131424MM15497
PathwayREACTOME_KINESINS

KIF21B KIF23 KIF2C

6.43e-0457423MM15714
PathwayREACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT

BICD2 KIF21B KIF23 KIF2C

6.60e-04134424M27751
PathwayREACTOME_MITOTIC_TELOPHASE_CYTOKINESIS

KIF23 SMC1A

6.62e-0413422M27661
PathwayREACTOME_MITOTIC_TELOPHASE_CYTOKINESIS

KIF23 SMC1A

6.62e-0413422MM15363
PathwayREACTOME_KINESINS

KIF21B KIF23 KIF2C

7.85e-0461423M977
PathwayREACTOME_M_PHASE

KIF23 SMC1A SDCCAG8 ZWINT CHMP2B KIF2C

9.36e-04387426MM15364
PathwayREACTOME_RHO_GTPASE_EFFECTORS

ROCK2 MYH10 PPP1R12A ZWINT KIF2C

9.50e-04257425MM14755
PathwayREACTOME_HIV_LIFE_CYCLE

TCEA1 GTF2H3 RNMT CHMP2B

9.82e-04149424M4076
PathwayWP_REGULATION_OF_ACTIN_CYTOSKELETON

ROCK2 MYH10 PPP1R12A MSN

1.01e-03150424M39520
PathwayWP_REGULATION_OF_ACTIN_CYTOSKELETON

ROCK2 MYH10 PPP1R12A MSN

1.06e-03152424MM15834
PathwayREACTOME_TRANSCRIPTION_OF_THE_HIV_GENOME

TCEA1 GTF2H3 RNMT

1.17e-0370423M27008
PathwayWP_CHEMOKINE_SIGNALING

ROCK2 PTK2B PLCB4 ADCY5

1.43e-03165424M39400
PathwayREACTOME_RHO_GTPASES_ACTIVATE_CIT

MYH10 PPP1R12A

1.43e-0319422M27489
PathwayREACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE

ROCK2 MYH10

1.59e-0320422M18415
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

TCEA1 RPL29 MYH10 RBM27 PPP1R12A SMC1A MRPS15 MRPS35 PLEC ECPAS ENSA CHMP2B VAT1 MSN

1.75e-081149641435446349
Pubmed

The Rho-Rock-Myosin signaling axis determines cell-cell integrity of self-renewing pluripotent stem cells.

ROCK2 MYH10 PPP1R12A

5.93e-08564318714354
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

RPL29 MYH10 KIF23 MAP7D3 RBM27 SYNM PPP1R12A SMC1A MRPS35 CKAP2 PLEC KIF2C MSN

3.99e-071257641336526897
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

BICD2 TCEA1 URB1 GTF2H3 MAP7D3 RBM27 PPP1R12A PLEC TMCO1 CHMP2B

7.90e-07724641036232890
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

RPL29 MYH10 GTF2H3 PPP1R12A SMC1A MRPS35 CKAP2 PLEC ECPAS KIF2C

2.14e-06809641032129710
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

KIF23 CKAP2 PLEC TMCO1 CDCA7L CHMP2B

2.53e-0621064616565220
Pubmed

Testosterone promotes vascular endothelial cell migration via upregulation of ROCK-2/moesin cascade.

ROCK2 MSN

3.33e-06264224065547
Pubmed

A standardized kinesin nomenclature.

KIF23 KIF2C

3.33e-06264215479732
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

ROCK2 RPL29 MYH10 KIF23 CCDC47 PPP1R12A SMC1A ECPAS ENSA RGS10 CHMP2B MSN

3.39e-061284641217353931
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

KIF21B TAOK3 PPP1R12A PLCB4 ECPAS HYDIN RYR3 KIF2C

3.61e-0649764836774506
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

ROCK2 RPL29 MYH10 KIF23 RNMT CCDC47 ECPAS ENSA CHMP2B KIF2C VAT1 MSN

6.41e-061367641232687490
Pubmed

Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.

KIF21B PTK2B MYH10 PPP1R12A

7.32e-066764429254152
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

KIF23 MAP7D3 RBM27 SYNM PLEC MSN

7.87e-0625664633397691
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

RPL29 MYH10 KIF23 MAP7D3 PPP1R12A SMC1A MRPS15 PLEC KIF2C MSN

8.71e-06949641036574265
Pubmed

Phasic contractions of isolated human myometrium are associated with Rho-kinase (ROCK)-dependent phosphorylation of myosin phosphatase-targeting subunit (MYPT1).

ROCK2 PPP1R12A

9.99e-06364222155728
Pubmed

Phosphorylation of the myosin phosphatase targeting subunit and CPI-17 during Ca2+ sensitization in rabbit smooth muscle.

ROCK2 PPP1R12A

9.99e-06364212563012
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ROCK2 MYH10 INTS12 CCDC47 PPP1R12A MRPS35 PLEC ABCC2 TMCO1 VAT1 BBOF1 MSN

1.10e-051442641235575683
Pubmed

Vascular endothelial growth factor C promotes cervical cancer metastasis via up-regulation and activation of RhoA/ROCK-2/moesin cascade.

ROCK2 MSN

2.00e-05464220429915
Pubmed

Myosin light chain kinase activation and calcium sensitization in smooth muscle in vivo.

ROCK2 PPP1R12A

2.00e-05464218524939
Pubmed

Mechanosensory hair cells express two molecularly distinct mechanotransduction channels.

PIEZO2 TMC1

2.00e-05464227893727
Pubmed

Impaired vascular remodeling in the yolk sac of embryos deficient in ROCK-I and ROCK-II.

ROCK2 PPP1R12A

2.00e-05464221895889
Pubmed

Genetic variants in GCKR, GIPR, ADCY5 and VPS13C and the risk of severe sulfonylurea-induced hypoglycaemia in patients with type 2 diabetes.

GCKR ADCY5

2.00e-05464222956255
Pubmed

Effects of genetic variants in ADCY5, GIPR, GCKR and VPS13C on early impairment of glucose and insulin metabolism in children.

GCKR ADCY5

2.00e-05464221789219
Pubmed

Phosphorylation of the regulatory subunit of smooth muscle protein phosphatase 1M at Thr850 induces its dissociation from myosin.

ROCK2 PPP1R12A

2.00e-05464212220642
Pubmed

Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle.

ROCK2 PPP1R12A

2.00e-05464212600888
Pubmed

Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase.

ROCK2 PPP1R12A

2.00e-05464210601309
Pubmed

Cortical mechanics and meiosis II completion in mammalian oocytes are mediated by myosin-II and Ezrin-Radixin-Moesin (ERM) proteins.

MYH10 MSN

2.00e-05464220660156
Pubmed

Global landscape of HIV-human protein complexes.

BICD2 KIF21B PTK2B CCDC47 PPP1R12A SDCCAG8 MSN

2.10e-0545764722190034
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

ROCK2 KIF21B RPL29 MYH10 SMC1A MRPS15 PLEC CCDC93 MSN

2.40e-0584764935235311
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

ROCK2 MAP7D3 PPP1R12A SMC1A SDCCAG8 MRPS35 PLEC CCDC93 CCDC144A KIF2C CCDC40

2.66e-051321641127173435
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

RPL29 MYH10 RBM27 PPP1R12A SMC1A PLEC MSN

2.76e-0547764731300519
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RPL29 URB1 MYH10 KIF23 CCDC47 SMC1A MRPS15 PLEC CCDC93 KIF2C MSN

3.32e-051353641129467282
Pubmed

The DNA methyltransferase DNMT3C protects male germ cells from transposon activity.

SYCP3 PIWIL2

3.32e-05564227856912
Pubmed

Integrin-linked kinase phosphorylates the myosin phosphatase target subunit at the inhibitory site in platelet cytoskeleton.

ROCK2 PPP1R12A

3.32e-05564211931630
Pubmed

Rho-kinase regulates endothelin-1-stimulated IL-6 synthesis via p38 MAP kinase in osteoblasts.

ROCK2 PPP1R12A

3.32e-05564217825250
Pubmed

Temporally and spatially selective loss of Rec8 protein from meiotic chromosomes during mammalian meiosis.

SMC1A SYCP3

3.32e-05564212759374
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

RPL29 MYH10 KIF23 RNMT SMC1A PLEC ECPAS

3.45e-0549464726831064
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

RPL29 TAOK3 RBM27 CCDC47 PPP1R12A SMC1A PLEC MSN

4.29e-0570164830196744
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

KIF23 CCDC47 PPP1R12A SMC1A MRPS35 PLEC ECPAS CHMP2B MSN

4.41e-0591664932203420
Pubmed

All kinesin superfamily protein, KIF, genes in mouse and human.

KIF21B KIF23 KIF2C

4.42e-053764311416179
Pubmed

Cutting edge: integration of human T lymphocyte cytoskeleton by the cytolinker plectin.

PLEC MSN

4.98e-05664211441066
Pubmed

Rho-kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closure.

ROCK2 MYH10

4.98e-05664226040287
Pubmed

Shroom regulates epithelial cell shape via the apical positioning of an actomyosin network.

ROCK2 MYH10

4.98e-05664216249236
Pubmed

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.

GCKR ADCY5

4.98e-05664220081857
Pubmed

Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes.

PLEC MSN

4.98e-05664217515952
Pubmed

KAP regulates ROCK2 and Cdk2 in an RNA-activated glioblastoma invasion pathway.

ROCK2 PPP1R12A

4.98e-05664224704824
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RPL29 MYH10 KIF23 MAP7D3 RBM27 PPP1R12A CKAP2 ENSA CHMP2B

5.13e-0593464933916271
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

BICD2 TCEA1 KIF21B RNMT MRPS15 MRPS35 CKAP2 KIF2C

5.32e-0572364834133714
Pubmed

An Interaction Network of the Human SEPT9 Established by Quantitative Mass Spectrometry.

MYH10 RBM27 PPP1R12A

6.96e-054364330975701
Pubmed

Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A.

SMC1A ZWINT

6.96e-05764211682612
Pubmed

Pinpointing the expression of piRNAs and function of the PIWI protein subfamily during spermatogenesis in the mouse.

SYCP3 PIWIL2

6.96e-05764221539824
Pubmed

GPAT2 is required for piRNA biogenesis, transposon silencing, and maintenance of spermatogonia in mice†.

SYCP3 PIWIL2

6.96e-05764230951587
Pubmed

PIEZO2 mediates ultrasonic hearing via cochlear outer hair cells in mice.

PIEZO2 TMC1

6.96e-05764234244441
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

URB1 KIF23 MAP7D3 RBM27 SMC1A CKAP2 CHMP2B KIF2C

7.47e-0575964835915203
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

RPL29 URB1 MYH10 KIF23 RNMT RBM27 SMC1A PLEC KIF2C

7.94e-0598964936424410
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

MYH10 MAP7D3 SYNM CCDC47 MRPS15 MRPS35 CKAP2 TMCO1 CHMP2B KIF2C VAT1

8.19e-051496641132877691
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

ROCK2 BICD2 RBM27 CCDC47 TMCO1 CHMP2B VAT1

8.29e-0556864737774976
Pubmed

Sequential assembly of centromeric proteins in male mouse meiosis.

SYCP3 KIF2C

9.27e-05864219283064
Pubmed

EED is required for mouse primordial germ cell differentiation in the embryonic gonad.

SYCP3 PIWIL2

9.27e-05864235679863
Pubmed

The Piezo channel is a mechano-sensitive complex component in the mammalian inner ear hair cell.

PIEZO2 TMC1

9.27e-05864238228630
Pubmed

SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation.

SYCP3 PIWIL2

9.27e-05864232674113
Pubmed

Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases.

ROCK2 PPP1R12A

9.27e-05864225816133
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

TCEA1 KIF23 RNMT RBM27 SMC1A PLEC ECPAS CDCA7L MSN

9.60e-05101464932416067
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

RPL29 MYH10 KIF23 CCDC47 SMC1A PLEC MSN

1.18e-0460164733658012
Pubmed

Statins improve NASH via inhibition of RhoA and Ras.

ROCK2 MSN

1.19e-04964227634010
Pubmed

Substrate-driven assembly of a translocon for multipass membrane proteins.

CCDC47 TMCO1

1.19e-04964236261522
Pubmed

The molecular basis of vascular lumen formation in the developing mouse aorta.

MYH10 MSN

1.19e-04964219853564
Pubmed

MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline.

SYCP3 PIWIL2

1.19e-04964221397847
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

RPL29 URB1 KIF23 INTS12 MAP7D3 RBM27 SMC1A CKAP2 CDCA7L KIF2C

1.19e-041294641030804502
Pubmed

Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment.

ROCK2 PTK2B SDCCAG8 PLCB4

1.36e-0414164420056178
Pubmed

RAD21L, a novel cohesin subunit implicated in linking homologous chromosomes in mammalian meiosis.

SMC1A SYCP3

1.49e-041064221242291
Pubmed

MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs.

SYCP3 PIWIL2

1.49e-041064220547853
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

RPL29 URB1 MYH10 KIF23 RBM27 PPP1R12A SMC1A CDCA7L

1.59e-0484764835850772
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

BICD2 MYH10 MAP7D3 SDCCAG8 CKAP2 PLEC ECPAS ENSA

1.67e-0485364828718761
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PTK2B KIF23 INTS12 MAP7D3 PPP1R12A CKAP2 PLEC KIF2C

1.78e-0486164836931259
Pubmed

Genome-Wide CRISPR-Cas9 Screen Reveals Selective Vulnerability of ATRX-Mutant Cancers to WEE1 Inhibition.

RNMT RBM27 SMC1A

1.79e-045964331551363
Pubmed

An ER translocon for multi-pass membrane protein biogenesis.

CCDC47 TMCO1

1.81e-041164232820719
Pubmed

Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference.

KIF23 KIF2C

1.81e-041164215843429
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

TCEA1 KIF23 MAP7D3 RBM27 PPP1R12A CKAP2 KIF2C

1.82e-0464564725281560
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

HOXA9 ANKRD31 PLEC VAT1

1.82e-0415264434299191
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

ROCK2 TCEA1 MYH10 RBM27 SYNM SMC1A ECPAS

1.96e-0465364733742100
Pubmed

RNF38 suppress growth and metastasis via ubiquitination of ACTN4 in nasopharyngeal carcinoma.

MYH10 PPP1R12A PLEC

2.08e-046264335568845
Pubmed

Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases.

MYH10 RBM27 PPP1R12A PLEC MSN

2.15e-0429564526209609
Pubmed

A new meiosis-specific cohesin complex implicated in the cohesin code for homologous pairing.

SMC1A SYCP3

2.17e-041264221274006
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

RPL29 CCDC47 PPP1R12A SYCP3 ZWINT KIF2C BBOF1

2.29e-0467064722990118
Pubmed

Hypermethylation of UCHL1 Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN).

ANKRD31 MYH10 SYNM

2.39e-046564332120844
Pubmed

SWI/SNF chromatin remodeling complex is required for initiation of sex-dependent differentiation in mouse germline.

SYCP3 PIWIL2

2.57e-041364234912016
Pubmed

UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination.

TCEA1 MYH10 KIF23 MAP7D3 PPP1R12A KIF2C

2.88e-0449164636273042
Pubmed

TRIM8 interacts with KIF11 and KIFC1 and controls bipolar spindle formation and chromosomal stability.

BICD2 KIF2C

2.99e-041464231904480
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

ROCK2 MAP7D3 CCDC47 SMC1A ECPAS KIF2C MSN

3.20e-0470864739231216
Pubmed

Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis.

BICD2 PPP1R12A

3.45e-041564216417406
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

RPL29 MAP7D3 RBM27 SYNM

3.76e-0418464432908313
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ROCK2 KIF21B CCDC13 MYH10 KIF23 PPP1R12A KIF2C MSN

3.77e-0496364828671696
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

URB1 GTF2H3 INTS12 RBM27 CCDC47 PPP1R12A MRPS35 CKAP2 TMCO1 KIF2C

3.85e-041497641031527615
Pubmed

Gtsf1/Cue110, a gene encoding a protein with two copies of a CHHC Zn-finger motif, is involved in spermatogenesis and retrotransposon suppression in murine testes.

SYCP3 PIWIL2

3.93e-041664219735653
Pubmed

Sex-specific chromatin remodelling safeguards transcription in germ cells.

SYCP3 PIWIL2

3.93e-041664234880491
Pubmed

Near-atomic resolution visualization of human transcription promoter opening.

TCEA1 GTF2H3

3.93e-041664227193682
Pubmed

Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?

SYCP3 PIWIL2

3.93e-041664216787967
Pubmed

Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.

TCEA1 GTF2H3

3.93e-041664211313499
Pubmed

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.

ROCK2 BICD2 CCDC47 PLCB4 VAT1

4.07e-0433964537232246
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF21B KIF23 KIF2C

1.32e-0446393622
GeneFamilyGeneral transcription factors|Xeroderma pigmentosum complementation groups|DNA helicases|ERCC excision repair associated

TCEA1 GTF2H3

1.32e-0325392565
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

PTK2B MSN

5.20e-03503921293
GeneFamilyMitochondrial ribosomal proteins

MRPS15 MRPS35

1.26e-0279392646
CoexpressionZHONG_PFC_MAJOR_TYPES_NPCS

KIF23 SFRP1 CKAP2 ZWINT KIF2C

2.37e-05142635M39078
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

TCEA1 TAOK3 MYH10 KIF23 PIEZO2 RNMT RBM27 CCDC47 CHMP2B

2.59e-05656639M18979
CoexpressionFAN_EMBRYONIC_CTX_MICROGLIA_1

KIF23 SMC1A CKAP2 ZWINT KIF2C

3.61e-05155635M39041
CoexpressionAtlasDevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#1_top-relative-expression-ranked_1000

ROCK2 SYNM PPP1R12A PLCB4 ADCY5 RYR3

4.19e-06148616gudmap_developingLowerUrinaryTract_adult_bladder_1000_k1
CoexpressionAtlasDevelopingGonad_e16.5_testes_emap-8444_top-relative-expression-ranked_1000

BICD2 PTK2B KIF23 SFRP1 SYNM SYCP3 PIWIL2 PLEC ECPAS ZWINT MSN

1.88e-058196111gudmap_developingGonad_e16.5_testes_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000

URB1 KIF23 DTWD2 PIWIL2 CKAP2 CDCA7L KIF2C

7.68e-05361617gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_1000
CoexpressionAtlasDevelopingGonad_e14.5_ testes_emap-6710_top-relative-expression-ranked_200

SFRP1 SYCP3 PIWIL2 ZWINT MSN

9.38e-05159615gudmap_developingGonad_e14.5_ testes_200
CoexpressionAtlasDevelopingGonad_e18.5_testes_emap-11164_top-relative-expression-ranked_1000

BICD2 KIF23 SFRP1 SYNM SYCP3 PIWIL2 PLEC ECPAS ZWINT MSN

9.94e-058146110gudmap_developingGonad_e18.5_testes_1000
CoexpressionAtlasDevelopingGonad_P2_testes_emap-30171_top-relative-expression-ranked_1000

BICD2 KIF23 SFRP1 SYNM SYCP3 PIWIL2 PLEC ECPAS ZWINT MSN

1.04e-048196110gudmap_developingGonad_P2_testes_1000
CoexpressionAtlasDevelopingGonad_e14.5_ testes_emap-6710_top-relative-expression-ranked_1000

BICD2 PTK2B KIF23 SFRP1 SYNM SYCP3 PIWIL2 ECPAS ZWINT MSN

1.08e-048226110gudmap_developingGonad_e14.5_ testes_1000
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#2_top-relative-expression-ranked_1000

URB1 DTWD2 RBM27 PIWIL2 CKAP2 KIF2C

1.14e-04266616gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k2_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#4_top-relative-expression-ranked_500

SYNM PPP1R12A PLCB4 ADCY5

1.37e-0491614gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_500_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#1_top-relative-expression-ranked_200

SYNM PPP1R12A ADCY5

1.38e-0435613gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_200_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#1_top-relative-expression-ranked_1000

PPP1R12A PLCB4 ADCY5 RYR3

1.43e-0492614gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k1
CoexpressionAtlasDevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#3_top-relative-expression-ranked_100

SYCP3 PIWIL2

1.69e-047612gudmap_developingGonad_e14.5_ testes_100_k3
CoexpressionAtlasFetal Liver, SC.STSL.FL, IgM- CD24- CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Fetal Liver, avg-2

HOXA9 MYH10 KIF23 PLCB4 CKAP2 CDCA7L KIF2C

1.69e-04410617GSM791122_500
CoexpressionAtlasDevelopingGonad_e14.5_ testes_emap-6710_top-relative-expression-ranked_500

PTK2B SFRP1 SYNM SYCP3 PIWIL2 ZWINT MSN

1.71e-04411617gudmap_developingGonad_e14.5_ testes_500
CoexpressionAtlasDevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#1_top-relative-expression-ranked_100

SFRP1 ZWINT MSN

1.92e-0439613gudmap_developingGonad_e12.5_testes_k1_100
CoexpressionAtlasFetal Liver, SC.LTSL.FL, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Fetal Liver, avg-3

HOXA9 MYH10 KIF23 PLCB4 CKAP2 CDCA7L KIF2C

2.05e-04423617GSM791126_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_500

PPP1R12A ADCY5 RYR3

2.22e-0441613DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_500
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#2_top-relative-expression-ranked_500

SYNM PPP1R12A PLCB4 RYR3

2.37e-04105614gudmap_developingLowerUrinaryTract_P1_bladder_J_500_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#4_top-relative-expression-ranked_500

SYNM PPP1R12A PLCB4 ADCY5

2.55e-04107614gudmap_developingLowerUrinaryTract_adult_bladder_500_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#5_top-relative-expression-ranked_1000

KIF23 SFRP1 GTF2H3 CKAP2 ZWINT KIF2C

3.25e-04323616gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000_k5
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

ROCK2 KIF23 SMC1A ECPAS ZWINT KIF2C CCDC40

3.82e-04469617Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000

URB1 DTWD2 RBM27 PIWIL2 CKAP2 KIF2C

3.82e-04333616gudmap_dev gonad_e13.5_M_GermCell_Oct_k1_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#2_top-relative-expression-ranked_1000

SYNM CCDC47 PPP1R12A PLCB4 ADCY5 RYR3

4.07e-04337616gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_1000_k2
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

ROCK2 TCEA1 MYH10 PPP1R12A SMC1A CKAP2 ECPAS ZWINT

4.19e-04629618Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlasDevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#3_top-relative-expression-ranked_200

SFRP1 ZWINT MSN

4.51e-0452613gudmap_developingGonad_e14.5_ testes_200_k3
CoexpressionAtlasDevelopingGonad_P2_testes_emap-30171_k-means-cluster#2_top-relative-expression-ranked_1000

BICD2 KIF23 SFRP1 ECPAS ZWINT MSN

4.90e-04349616gudmap_developingGonad_P2_testes_1000_k2
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

URB1 KIF23 DTWD2 RBM27 SYCP3 PIWIL2 CKAP2 CDCA7L KIF2C

5.23e-04820619gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasDevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#3_top-relative-expression-ranked_1000

BICD2 KIF23 SFRP1 ECPAS ZWINT MSN

5.94e-04362616gudmap_developingGonad_e18.5_testes_1000_k3
CoexpressionAtlasDevelopingGonad_P2_testes_emap-30171_k-means-cluster#3_top-relative-expression-ranked_500

KIF23 SFRP1 ZWINT MSN

6.33e-04136614gudmap_developingGonad_P2_testes_500_k3
CoexpressionAtlasDevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#3_top-relative-expression-ranked_1000

BICD2 KIF23 SFRP1 ECPAS ZWINT MSN

7.44e-04378616gudmap_developingGonad_e16.5_testes_1000_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#5_top-relative-expression-ranked_1000

PPP1R12A PLCB4 RYR3

8.68e-0465613DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k5_1000
CoexpressionAtlasDevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#3_top-relative-expression-ranked_500

SYCP3 PIWIL2

9.49e-0416612gudmap_developingGonad_e16.5_testes_500_k3
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#5_top-relative-expression-ranked_100

SYCP3 PIWIL2

9.49e-0416612gudmap_developingGonad_e18.5_ovary_100_k5
CoexpressionAtlasDevelopingGonad_e12.5_testes_emap-29069_top-relative-expression-ranked_500

PTK2B KIF23 SFRP1 PIWIL2 ZWINT MSN

1.08e-03406616gudmap_developingGonad_e12.5_testes_500
CoexpressionAtlasDevelopingGonad_P2_testes_emap-30171_top-relative-expression-ranked_500

KIF23 SFRP1 SYNM PIWIL2 ZWINT MSN

1.10e-03408616gudmap_developingGonad_P2_testes_500
CoexpressionAtlasDevelopingGonad_e16.5_testes_emap-8444_top-relative-expression-ranked_500

SFRP1 SYNM SYCP3 PIWIL2 ZWINT MSN

1.12e-03409616gudmap_developingGonad_e16.5_testes_500
CoexpressionAtlasDevelopingGonad_e18.5_testes_emap-11164_top-relative-expression-ranked_500

SFRP1 SYNM SYCP3 PIWIL2 ZWINT MSN

1.16e-03412616gudmap_developingGonad_e18.5_testes_500
CoexpressionAtlasDevelopingGonad_P2_testes_emap-30171_top-relative-expression-ranked_200

SFRP1 SYNM PIWIL2 MSN

1.19e-03161614gudmap_developingGonad_P2_testes_200
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_k-means-cluster#1_top-relative-expression-ranked_200

SYCP3 PIWIL2

1.21e-0318612gudmap_developingGonad_P2_ovary_200_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#2_top-relative-expression-ranked_1000

PPP1R12A PLCB4 RYR3

1.22e-0373613gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k2
CoexpressionAtlasDevelopingGonad_e16.5_testes_emap-8444_top-relative-expression-ranked_200

SFRP1 SYNM PIWIL2 MSN

1.24e-03163614gudmap_developingGonad_e16.5_testes_200
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_top-relative-expression-ranked_200

SYNM PPP1R12A ADCY5 RYR3

1.27e-03164614gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_200
ToppCell356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MYH10 KIF23 PLCB4 CKAP2 RYR3 ZWINT KIF2C

9.38e-09186647722da08cd978249a19855fd3ec8ddda780c99d83
ToppCellCOVID-19-lung-Proliferative_fibroblast|lung / Disease (COVID-19 only), tissue and cell type

MYH10 KIF23 PIEZO2 CKAP2 ZWINT KIF2C

3.85e-071966462ce8a787f2731faa913d20342d73041d59468f27
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SFRP1 SYNM IQCJ-SCHIP1 PLCB4 ADCY5 RYR3

3.85e-07196646a58bdf9de05d13d84211e09a933679d485bf8ab4
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SFRP1 INTS12 SYNM IQCJ-SCHIP1 ADCY5 RYR3

3.96e-07197646f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / Treatment groups by lineage, cell group, cell type

FICD KIF23 INTS12 DTWD2 CKAP2 ZWINT

3.96e-07197646038fd92750257d43d5e980fd06d77742b543f11a
ToppCellNon-neuronal-Dividing-Radial_Glia-vRG-11|World / Primary Cells by Cluster

KIF23 SFRP1 CKAP2 CDCA7L ZWINT KIF2C

4.08e-07198646672c6faeed54e1397e12c0aac1a5cbd19c684f06
ToppCellNon-neuronal|World / Primary Cells by Cluster

KIF23 SFRP1 CKAP2 CDCA7L ZWINT KIF2C

4.20e-07199646165d9de6cedc79e13bb6fa244e8898a5dacc54ff
ToppCellNon-neuronal-Dividing|World / Primary Cells by Cluster

KIF23 SFRP1 CKAP2 CDCA7L ZWINT KIF2C

4.33e-0720064650fa7b34a05f2c5ebbc7d113bd8e31326688a231
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Stem_cells-Neuroepithelial_cell|3m / Sample Type, Dataset, Time_group, and Cell type.

KIF23 SFRP1 CKAP2 CDCA7L ZWINT KIF2C

4.33e-072006462938a029fa0478be561574ace91f95c4a528b2d4
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Stem_cells|3m / Sample Type, Dataset, Time_group, and Cell type.

KIF23 SFRP1 CKAP2 CDCA7L ZWINT KIF2C

4.33e-07200646cfe017b4a4d604a553d0a3df9659687f38e9a7af
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Stem_cells|GW16 / Sample Type, Dataset, Time_group, and Cell type.

KIF23 SFRP1 CKAP2 ZWINT KIF2C MSN

4.33e-07200646b71138729d2a81cc2f30e3bc15853516a525a17f
ToppCellNon-neuronal-Dividing-Radial_Glia-vRG|World / Primary Cells by Cluster

KIF23 SFRP1 CKAP2 CDCA7L ZWINT KIF2C

4.33e-072006467596143925cd403ec7baceef87d19d570e48586a
ToppCellNon-neuronal-Dividing-Radial_Glia|World / Primary Cells by Cluster

KIF23 SFRP1 CKAP2 CDCA7L ZWINT KIF2C

4.33e-07200646ecbbad00e16041a9e1cd88d8bd7279a1b52c0aa4
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Stem_cells-Stem_cells|GW16 / Sample Type, Dataset, Time_group, and Cell type.

KIF23 SFRP1 CKAP2 ZWINT KIF2C MSN

4.33e-072006468f3067b52865a0f5488e4df0d5a4fea80135cef5
ToppCellCOVID-19-Lymphoid-Proliferating_CD8_T_cells|Lymphoid / Condition, Lineage and Cell class

KIF23 SMC1A CKAP2 CDCA7L ZWINT KIF2C

4.33e-072006464556bb626ca1a00a6db13d2adb35acb8ba848f9c
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_immature_4|E18.5-samps / Age Group, Lineage, Cell class and subclass

HOXA9 KIF23 PDE6C CKAP2 KIF2C

1.24e-06130645169d88bffd7cd813a484d809defa638ceaca4bcb
ToppCellLPS-antiTNF-Unknown-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF23 CKAP2 ADCY5 ZWINT KIF2C

1.24e-06130645615c233c7c2600c1c2bc5cf5b1c501fc474564ef
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF23 ADCY5 RYR3 ZWINT KIF2C

1.34e-0613264502491930097b75aaeedab9e8200711b0dc610944
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SYNM PPP1R12A IQCJ-SCHIP1 ADCY5 RYR3

2.76e-06153645ec6fe6b8c884fa76adc7a0f9db041f7b1567a2ee
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ZCCHC4 KIF23 SYNM ZWINT KIF2C

3.65e-06162645a957c7e347189b72fbd47db3075bb5e879a21c67
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 PIWIL2 GCKR CKAP2 KIF2C

4.76e-06171645621f9da0bfa09c86fc89fd26919403e94cd56d2b
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HOXA9 KIF21B KIF23 ZWINT KIF2C

6.27e-06181645e4dbc09f0210de465d8347969b301c22463a2b7d
ToppCell356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|356C / Donor, Lineage, Cell class and subclass (all cells)

KIF23 CKAP2 RYR3 ZWINT KIF2C

6.27e-06181645be4f35c9eb5b3083acb2264128f095fac1f3da45
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC13 KIF23 CKAP2 ZWINT KIF2C

6.62e-0618364529b62dd542bc3f8df843998f577724f3818d4271
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic|lymph-node_spleen / Manually curated celltypes from each tissue

KIF23 IQCJ-SCHIP1 GCKR ZWINT KIF2C

6.97e-06185645912d8efdc37820dbb07736221a98af929e5a7c97
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA9 KIF23 CKAP2 ZWINT KIF2C

7.74e-06189645fd8834d1feb7f63911c5fa51efb1f679a8baddeb
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

ROCK2 MYH10 PPP1R12A PLCB4 RYR3

7.74e-061896456b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA9 KIF23 CKAP2 ZWINT KIF2C

7.94e-06190645cd37ccd30c27cf65eda0a9165f35b7672f5acaf6
ToppCellmild-Myeloid-Immature_Neutrophils_2|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIF23 CDCA7L ZWINT KIF2C VAT1

8.35e-061926450445fdc670fa7b847dcd0a061d7736ddcf3519ba
ToppCellcontrol-Myeloid-Immature_Neutrophils_2|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIF23 CDCA7L ZWINT KIF2C VAT1

8.56e-0619364533349830e9eba506470ad3661fad5e5a283d20ca
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_DC1|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

KIF23 CKAP2 ENSA ZWINT KIF2C

8.56e-0619364542775588e788c330aade07e54b208f1c2eea3ab3
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

MYH10 PIEZO2 INTS12 SYCP3 L3MBTL4

8.56e-061936455896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KIF23 CKAP2 CDCA7L ZWINT KIF2C

8.56e-06193645ecbe1bd16df547427da5e69a3017300e766c2899
ToppCellcontrol-Myeloid-Immature_Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIF23 CDCA7L ZWINT KIF2C VAT1

9.00e-06195645bfaceb0601cf3855f38d6e1f482f01ad03ef11fe
ToppCellCOVID-19-lung-Proliferative_fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

KIF23 PIEZO2 CKAP2 ZWINT KIF2C

9.23e-06196645ca91d5e325875e7444809b80fcbd491d8899ea36
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH10 KIF23 CKAP2 ZWINT KIF2C

9.46e-06197645196eaecef7003ed83f323c1f157c6a3594650097
ToppCellmild-Myeloid-Immature_Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIF23 CDCA7L ZWINT KIF2C VAT1

9.46e-06197645bd9d57e0c873f6526dca322f4dad8e6bd692586c
ToppCellsevere-Myeloid-Immature_Neutrophils_2|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIF23 CDCA7L ZWINT KIF2C VAT1

9.69e-06198645844f534551483c89ef789d1cfeb4680e54f794b2
ToppCellsevere-Myeloid-Immature_Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIF23 CDCA7L ZWINT KIF2C VAT1

9.69e-06198645e36303628af3139310c1d7a84d2919b7319bbda4
ToppCell18-Airway-Mesenchymal-Mesenchyme_RSPO2+|Airway / Age, Tissue, Lineage and Cell class

KIF23 PIEZO2 CKAP2 ZWINT KIF2C

9.93e-061996457ac35e8f45dcdc702422dabd8f3e4d03e2bf61af
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_IN_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

KIF23 CKAP2 CDCA7L ZWINT KIF2C

9.93e-06199645f315ec3fb6c0799668c9195f836a77fc0db2b615
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors_nGenesUnder4k|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

KIF23 SFRP1 CKAP2 ZWINT KIF2C

9.93e-061996452fbf94f7858250088e0f5ce1ff51892730a13ae8
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells-Neuroepithelial_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

KIF23 CKAP2 CDCA7L ZWINT KIF2C

1.02e-052006458f8b8c225cdc79baf16fe04be89bdb65e404a055
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells|10w / Sample Type, Dataset, Time_group, and Cell type.

KIF23 CKAP2 CDCA7L ZWINT KIF2C

1.02e-05200645a1f48eca9efb4f3ec3c9ace20f8c9257dd72c4ed
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Stem_cells|GW10 / Sample Type, Dataset, Time_group, and Cell type.

KIF23 SFRP1 CKAP2 ZWINT KIF2C

1.02e-052006454c22a1f35ff496fa6af2ab171f2936785272bc06
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell|2m / Sample Type, Dataset, Time_group, and Cell type.

KIF23 CKAP2 CDCA7L ZWINT KIF2C

1.02e-052006450d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

KIF23 SMC1A CKAP2 ZWINT KIF2C

1.02e-052006455f2fbd789cc16af411a01c3199583888b260ae91
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Stem_cells|GW10 / Sample Type, Dataset, Time_group, and Cell type.

KIF23 SFRP1 CKAP2 ZWINT KIF2C

1.02e-05200645474e6ab48f199315f3cca86b81fdf54e0461b7b8
ToppCell356C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

KIF23 SMC1A CKAP2 ZWINT KIF2C

1.02e-05200645548a0f486ab8745da107f2815914dbf873a6e3c8
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Stem_cells-Neuroepithelial_cell|GW09 / Sample Type, Dataset, Time_group, and Cell type.

KIF23 SFRP1 CKAP2 ZWINT KIF2C

1.02e-05200645c88d8e67647c90d1fa2569516865a9fd766eaf1c
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells|2m / Sample Type, Dataset, Time_group, and Cell type.

KIF23 CKAP2 CDCA7L ZWINT KIF2C

1.02e-052006450675f580ccef705875854247bbfd4ee2bcf126a1
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Proliferating|3_mon / Sample Type, Dataset, Time_group, and Cell type.

KIF23 CKAP2 CDCA7L ZWINT KIF2C

1.02e-052006459279415f5e76cb5b4e071c6582ac249b72dd694c
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating|1_mon / Sample Type, Dataset, Time_group, and Cell type.

KIF23 SFRP1 CKAP2 ZWINT KIF2C

1.02e-05200645762442d125e594fede4506b72da15563b1d8798a
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_ventral_progenitors|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

KIF23 CKAP2 CDCA7L ZWINT KIF2C

1.02e-052006459359faa749f41aaef70b4874f20b4eed2dc12cc2
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Proliferating-Cycling|3_mon / Sample Type, Dataset, Time_group, and Cell type.

KIF23 CKAP2 CDCA7L ZWINT KIF2C

1.02e-05200645d582385b2dbb25eeba1b22c5d258a8f26a40ef8b
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF23 SMC1A CKAP2 ZWINT KIF2C

1.02e-0520064543571c9284d4e41402a2d1eefc1efe2ce8476d4a
ToppCellNon-neuronal-Dividing-IPC|World / Primary Cells by Cluster

KIF23 SFRP1 CKAP2 ZWINT KIF2C

1.02e-05200645971533181daa1bfac1f1b8c507d2013f891f9078
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Stem_cells|GW09 / Sample Type, Dataset, Time_group, and Cell type.

KIF23 SFRP1 CKAP2 ZWINT KIF2C

1.02e-0520064528935053cd6918cd2e9f3e7691f8522216585cb6
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

KIF23 CKAP2 CDCA7L ZWINT KIF2C

1.02e-052006452154c976f96489d0fa7bfe6ac1cd21edcbefe735
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Stem_cells-Neuroepithelial_cell|GW10 / Sample Type, Dataset, Time_group, and Cell type.

KIF23 SFRP1 CKAP2 ZWINT KIF2C

1.02e-052006450632b8d3a1be437f146bc86aae9646303e37a0bd
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors_nGenesUnder4k|1_mon / Sample Type, Dataset, Time_group, and Cell type.

KIF23 SFRP1 CKAP2 ZWINT KIF2C

1.02e-05200645243c7f88befd402a57e9226706811c802b28e3fd
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Stem_cells-Stem_cells|GW10 / Sample Type, Dataset, Time_group, and Cell type.

KIF23 SFRP1 CKAP2 ZWINT KIF2C

1.02e-0520064501a29651e9bb64ef7666c6a61ec396eeb88b2816
ToppCellLPS-antiTNF-Unknown|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF23 CKAP2 ADCY5 ZWINT

3.59e-05129644739b263296c28554967362060b154f7a95e1341d
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF23 CKAP2 ZWINT KIF2C

4.16e-051346444d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chodl|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SFRP1 L3MBTL4 CCDC40 VAT1

4.54e-051376445cb84392e4483f50e09fb7395e2ec98f3eb6ecf3
ToppCellEndothelial-Endothelial-H_(cycle)|Endothelial / shred on cell class and cell subclass (v4)

URB1 KIF23 CKAP2 KIF2C

4.67e-05138644a1f41a5a9da40adcc343722baef78c603599c3f0
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PIWIL2 HYDIN RYR3 L3MBTL4

5.51e-0514464408005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF23 CKAP2 ZWINT KIF2C

6.62e-05151644c06a54afe918b14f885d6a85fbcf81e80f33afae
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

HOXA9 INTS12 L3MBTL4 VAT1

6.97e-05153644e7d20c88466ff81db613869cf7a6a4bb95fd6c2f
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

MYH10 PLCB4 ADCY5 RYR3

8.49e-0516164464891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF23 CKAP2 ZWINT KIF2C

8.49e-051616442165897924c790fec43502283f1df221c56c1e9f
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF23 CKAP2 ZWINT KIF2C

8.91e-051636445285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF23 CKAP2 RYR3 KIF2C

9.12e-051646444307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF23 CKAP2 RYR3 KIF2C

9.12e-051646441d84aa5b925f502ee9c5fa39714490f613a58028
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF23 CKAP2 ZWINT KIF2C

9.34e-05165644eec2d327c94832d1390314c93ef6a2be4648478b
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KIF23 SYNM ZWINT KIF2C

9.34e-05165644a5c3af634d2698f9a01cf074791756b7669f9fff
ToppCell343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell|343B / Donor, Lineage, Cell class and subclass (all cells)

HOXA9 RYR3 ZWINT KIF2C

9.78e-05167644315cde87eed2b42a1b9b068fae94caa10ec64c70
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF23 CKAP2 ZWINT KIF2C

1.00e-04168644d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellEndothelial-B-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

HOXA9 SFRP1 PIEZO2 SYNM

1.00e-041686444977c3837fbb1f36c89fddd5764e37290ac25ad8
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BICD2 PIEZO2 COLGALT2 MSN

1.02e-0416964441ad349806b279fbe1374b7e3cc7f146a11adb44
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 KIF23 CKAP2 KIF2C

1.02e-04169644563c267edaade0e5df192ad953801ef9768d4270
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF23 CKAP2 ZWINT KIF2C

1.02e-04169644e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellDividing_Macrophages-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

KIF23 CKAP2 ZWINT KIF2C

1.02e-04169644bc859a103cad567caf50c3c3882d2d2017807c73
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BICD2 PIEZO2 COLGALT2 MSN

1.02e-0416964442782c61592742190ab0cba8a94f8bdf9c278f90
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF21B KIF23 CKAP2 KIF2C

1.07e-041716446e7ade1d14a3ec4c566476aac3eb509bd2661e39
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIF23 CKAP2 ZWINT KIF2C

1.10e-041726447f3d0ef18f5df1ed80498d435b0378ca398c0b88
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTK2B FICD PLCB4 MSN

1.10e-041726449a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

MYH10 PLCB4 ADCY5 RYR3

1.12e-04173644a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYH10 SYNM PLCB4 ADCY5

1.12e-04173644cb6389536195443633adb06e5f1b7483530773d1
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 PIEZO2 CDCA7L KIF2C

1.12e-04173644f38bf7584e08d15a6e2c116b7c3551ba475a5e14
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA9 MYH10 PIEZO2 PLCB4

1.15e-041746449d22a554617a93701d0945de63cc3e7b24322c40
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF23 CKAP2 ZWINT KIF2C

1.15e-04174644dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Cycling_T|GI_small-bowel / Manually curated celltypes from each tissue

CCDC13 KIF23 ZWINT KIF2C

1.15e-04174644e4c8da80eca07e4396f57dad212f76c2eca4c1bd
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STMN4 KIF23 CKAP2 KIF2C

1.15e-041746441779e67382cb2644534ffb5b9b8f28d32935f4ea
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH10 KIF23 ZWINT KIF2C

1.17e-04175644cc596907ea1a64ab7b5a8c7d4ad12e6ee59bfed9
ToppCell10x_5'_v1-Neoplastic-Stem-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH10 KIF23 ZWINT KIF2C

1.17e-04175644a8400e7e47379901dcab5f2e364c3ff17765b4b9
ToppCellCOVID-19-kidney-Podocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

TMC1 INTS12 IQCJ-SCHIP1 RYR3

1.17e-04175644a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCellRSV-Healthy-2|Healthy / Virus stimulation, Condition and Cluster

ZCCHC4 CKAP2 ZWINT KIF2C

1.17e-04175644c47440c0b0513e67fe13b85f10dd8a8d42d0e9a3
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KIF23 CDCA7L ZWINT KIF2C

1.17e-041756440b1aaa028ba844d4bcb4509fdab8bee648373935
ToppCell10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH10 KIF23 ZWINT KIF2C

1.17e-041756448a3abf40146ae3459d97cdf865c1c8f6b92ac639
Drugnocodazole

ROCK2 BICD2 PTK2B MYH10 KIF23 PPP1R12A SDCCAG8 CKAP2 ZWINT KIF2C

8.16e-074776410CID000004122
Diseasecorpus callosum volume measurement

DTWD2 IQCJ-SCHIP1 PLEC L3MBTL4

5.59e-05100614EFO_0010299
DiseaseAqueductal Stenosis

MYH10 HYDIN

1.17e-048612C2936786
Diseasedisease progression measurement

IQCJ-SCHIP1 ADCY5 RYR3

2.78e-0461613EFO_0008336
Diseasemyeloid white cell count

BICD2 HOXA9 PTK2B RNMT GCKR ADCY5 CDCA7L VAT1

6.66e-04937618EFO_0007988
Diseaseplatelet crit

BICD2 HOXA9 ANKRD31 RBM27 GCKR PLEC ADCY5 CCDC40

7.39e-04952618EFO_0007985
DiseaseBMI-adjusted fasting blood glucose measurement

GCKR ADCY5

1.03e-0323612EFO_0008036
Diseasegestational diabetes

PPP1R12A GCKR

1.03e-0323612EFO_0004593
Diseasefasting blood glucose measurement, HOMA-B, fasting blood insulin measurement

GCKR ADCY5

1.22e-0325612EFO_0004465, EFO_0004466, EFO_0004469
Diseaseglucose tolerance test

GCKR ADCY5

1.43e-0327612EFO_0004307
Diseaselysophosphatidylethanolamine 20:4 measurement

SFRP1 GCKR

1.65e-0329612EFO_0010370
DiseaseEpileptic encephalopathy

SMC1A RYR3

1.76e-0330612C0543888

Protein segments in the cluster

PeptideGeneStartEntry
NMAKAKMKNKQLPSA

ENSA

71

O43768
QKLKQQLMQMEREKA

BICD2

346

Q8TD16
TQKRKEEKAMIAKMN

ADCY5

646

O95622
KNKRKLRKMELLMNS

DTWD2

281

Q8NBA8
QMKDREMNRVKKLAK

BBOF1

336

Q8ND07
AKTMQAVNKKMDPQK

CHMP2B

106

Q9UQN3
KKQMTTEKQKQDANM

CKAP2

156

Q8WWK9
KQEAMKLQQDMRKKR

RBM27

816

Q9P2N5
NKNMKPEERANIMKT

RBM27

851

Q9P2N5
DFKKMQDKTQMQEKA

RGS10

76

O43665
QLNAMKRLQMVKKKA

INTS12

441

Q96CB8
KLREDLQEQMNKNKM

ANKRD31

71

Q8N7Z5
MKRQGKREKAQKLFM

FICD

116

Q9BVA6
LRREQKKLEKKQMKM

CCDC47

461

Q96A33
KKKMRMSEQQDLERN

ECPAS

766

Q5VYK3
RNEEMKAAMKKLQNR

OR4K14

291

Q8NGD5
KMNKLENRKDIAQEM

PDE6C

441

P51160
KKAKVALMKQMREEQ

KIF21B

756

O75037
NRRMKMKKINKDRAK

HOXA9

256

P31269
MKQPNRKRKLNMDSK

L3MBTL4

1

Q8NA19
KQMERAMLENEKKKR

MSN

316

P26038
KQEEQMRKQEEQMRK

GOLGA6L7

301

A0A1B0GV03
KQMLKQKEQMRKQEE

GOLGA6L7

346

A0A1B0GV03
NMKNKDKRLKIMNEI

ABCC2

491

Q92887
KRTMNIKENKAMLAQ

CDCA7L

216

Q96GN5
ERMQKMQEKQKAFVL

GCKR

231

Q14397
KMEKKKQENKMRRDQ

CCDC93

576

Q567U6
MSEKEELNKKKRNMG

HYDIN

2411

Q4G0P3
LDNDLKKLNMLMNKN

CCDC40

836

Q4G0X9
MQHKRLQKQMEKKRE

CCDC13

21

Q8IYE1
EKIKNNENKMLLKRM

RNMT

401

O43148
MQQRVIKKSKDMAKE

MAP7D3

626

Q8IWC1
MKQNLERKNKMLRKE

CCDC196

96

A0A1B0GTZ2
KQMQENLKPKQFRKM

PTK2B

216

Q14289
SKQKELEMARKKMNS

CCDC144A

791

A2RUR9
KKKLMKLMDNIDQAQ

COLGALT2

446

Q8IYK4
MKNKREEKKAQNSEM

KIF2C

201

Q99661
GKKAMVNKDDIQKMN

MYH10

66

P35580
QMEKANARMKQLKRQ

MYH10

1871

P35580
KENHMQGKLNEKEKM

KIF23

536

Q02241
KKGLKKMQANNAKAM

RPL29

51

P47914
EMANKKEMLKIKQEQ

MRPS15

96

P82914
LLQMKAAEKNMEINK

MRPS35

266

P82673
AMKQSKEMDQLKKVQ

PLCB4

1126

Q15147
KLKNNNRDLSMVRMK

TMCO1

126

Q9UM00
QNEFKKEMAMLQKKI

SYCP3

201

Q8IZU3
KEQAMFDKKVQLQRM

SYNM

1521

O15061
KMKKDFRAMKDLAQQ

PIWIL2

506

Q8TC59
SQQEKRAIEKDMMKK

SDCCAG8

381

Q86SQ7
NLKAMEMQIKKQFQD

TAOK3

711

Q9H2K8
VRFAKKMDKMVQKKN

TCEA1

6

P23193
NFIKMAKEKLAQKME

STMN4

136

Q9H169
RQKKLQAEAKMALAM

IQCJ-SCHIP1

436

B3KU38
NKEFKNFMKKMKNHE

SFRP1

291

Q8N474
QARELMKMLKDKNKP

URB1

2006

O60287
ANLDLKKKMKMQALE

TMC1

726

Q8TDI8
NKMRNKKMAAARAAA

TMC1

741

Q8TDI8
EQLQAKKQMAMEKRR

ZWINT

136

O95229
KKRKAQAAEMKAANE

RYR3

4321

Q15413
KKSMDQLKRQMDRIK

PIEZO2

1471

Q9H5I5
EMKMNLEKQNAELRK

ROCK2

836

O75116
KKKELGKMMREQQQI

SMC1A

266

Q14683
QRALAEKMLKEKMQA

PLEC

2441

Q15149
KVADAMKQMQEKKNV

VAT1

366

Q99536
VRKQKQRKSNKMKME

ZCCHC4

471

Q9H5U6
RMNKEVKDNQEMKSR

GTF2H3

146

Q13889
EKRLNMALQMSNFKK

WDR64

6

B1ANS9
MKMADAKQKRNEQLK

PPP1R12A

1

O14974