Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransporter activity

CACNA1S SLC9A8 SLC38A10 SLC36A1 SLCO4C1 P2RX4 SLC39A3 SLC22A16 SLC6A16 CLN3 SLC2A7 SLC35E2A NPC1L1 SLC34A2 SLC43A3 SLC35E2B SLC26A1 SLC6A14 CDH17 SLC22A31

5.04e-0712898720GO:0005215
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC9A8 SLC36A1 SLCO4C1 SLC6A16 SLC35E2A SLC34A2 SLC35E2B SLC26A1 SLC6A14 CDH17

6.44e-072968710GO:0015291
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1S SLC9A8 SLC38A10 SLC36A1 SLCO4C1 P2RX4 SLC39A3 SLC22A16 SLC6A16 SLC2A7 SLC35E2A SLC34A2 SLC43A3 SLC35E2B SLC26A1 SLC6A14 CDH17 SLC22A31

2.67e-0611808718GO:0022857
GeneOntologyMolecularFunctionvirus receptor activity

SERPINB3 SERPINB4 HYAL3 CD55 LAMP1

3.49e-0585875GO:0001618
GeneOntologyMolecularFunctionexogenous protein binding

SERPINB3 SERPINB4 HYAL3 CD55 LAMP1

3.69e-0586875GO:0140272
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC9A8 SLC36A1 SLCO4C1 SLC6A16 SLC35E2A SLC34A2 SLC35E2B SLC26A1 SLC6A14 CDH17

4.25e-054778710GO:0022804
GeneOntologyMolecularFunctioncarnitine transmembrane transporter activity

SLC22A16 SLC6A14

2.78e-046872GO:0015226
GeneOntologyMolecularFunctionnetrin receptor activity

UNC5A UNC5D

2.78e-046872GO:0005042
GeneOntologyMolecularFunctionamine transmembrane transporter activity

SLC22A16 SLC6A14

6.62e-049872GO:0005275
GeneOntologyMolecularFunctioncysteine-type endopeptidase inhibitor activity

SERPINB13 SERPINB3 SERPINB4

8.69e-0443873GO:0004869
GeneOntologyMolecularFunctionATP-dependent diacylglycerol kinase activity

DGKB DGKG

1.01e-0311872GO:0004143
GeneOntologyMolecularFunctionaromatic amino acid transmembrane transporter activity

SLC36A1 SLC6A14

1.42e-0313872GO:0015173
GeneOntologyBiologicalProcessregulation of cell killing

SLAMF6 SERPINB4 HLA-G CD55 LAMP1 HSPA8

3.72e-05147876GO:0031341
GeneOntologyBiologicalProcesspositive regulation of lymphocyte mediated immunity

RIF1 SLAMF6 HLA-G CD55 LAMP1 HSPA8

4.16e-05150876GO:0002708
GeneOntologyBiologicalProcessregulation of lymphocyte mediated immunity

RIF1 SLAMF6 SERPINB4 HLA-G CD55 LAMP1 HSPA8

5.66e-05232877GO:0002706
GeneOntologyBiologicalProcessorganic anion transport

SLC38A10 SLC36A1 SLCO4C1 P2RX4 CLN3 APBA1 SLC43A3 SLC26A1 SLC6A14 CYB5R1

6.17e-055158710GO:0015711
GeneOntologyBiologicalProcesspositive regulation of leukocyte mediated immunity

RIF1 SLAMF6 HLA-G CD55 LAMP1 HSPA8

9.79e-05175876GO:0002705
GeneOntologyCellularComponentapical part of cell

SLC9A8 SLC36A1 P2RX4 SLC39A3 SLC2A7 NPC1L1 CD55 SLC34A2 DUOX2 UPK3A SLC6A14

3.42e-055928711GO:0045177
GeneOntologyCellularComponentapical plasma membrane

SLC9A8 SLC36A1 SLC39A3 SLC2A7 NPC1L1 CD55 SLC34A2 DUOX2 UPK3A SLC6A14

3.45e-054878710GO:0016324
GeneOntologyCellularComponentlysosome

SLC36A1 SERPINB13 SLCO4C1 P2RX4 SERPINB3 CLN3 HYAL3 HLA-G LAMP1 FUCA2 HSPA8

5.34e-048118711GO:0005764
GeneOntologyCellularComponentlytic vacuole

SLC36A1 SERPINB13 SLCO4C1 P2RX4 SERPINB3 CLN3 HYAL3 HLA-G LAMP1 FUCA2 HSPA8

5.34e-048118711GO:0000323
DomainMFS_dom

SLCO4C1 SLC22A16 CLN3 SLC2A7 MFSD6 SLC43A3 SLC22A31

2.39e-06134847IPR020846
DomainDAG_kinase_N

DGKB DGKG

5.98e-053842PF14513
DomainDAG_kinase_typeI_N

DGKB DGKG

5.98e-053842IPR029477
Domain-

DGKB DGKG

5.98e-0538421.10.238.110
DomainMFS

SLCO4C1 SLC22A16 SLC2A7 MFSD6 SLC22A31

1.26e-04108845PS50850
DomainUPA

UNC5A UNC5D

1.98e-045842IPR033772
DomainSterol-sensing

NPC1L1 PTCH2

1.98e-045842PF12349
DomainUPA

UNC5A UNC5D

1.98e-045842PF17217
DomainSerpin_CS

SERPINB13 SERPINB3 SERPINB4

3.96e-0432843IPR023795
DomainMFS_sugar_transport-like

SLC22A16 SLC2A7 SLC22A31

5.63e-0436843IPR005828
DomainSerpin_dom

SERPINB13 SERPINB3 SERPINB4

5.63e-0436843IPR023796
DomainSugar_tr

SLC22A16 SLC2A7 SLC22A31

5.63e-0436843PF00083
DomainSERPIN

SERPINB13 SERPINB3 SERPINB4

6.11e-0437843SM00093
DomainSERPIN

SERPINB13 SERPINB3 SERPINB4

6.11e-0437843PS00284
DomainSerpin

SERPINB13 SERPINB3 SERPINB4

6.61e-0438843PF00079
DomainZU5

UNC5A UNC5D

7.05e-049842SM00218
DomainPtc/Disp

NPC1L1 PTCH2

7.05e-049842IPR003392
DomainPatched

NPC1L1 PTCH2

7.05e-049842PF02460
DomainSerpin_fam

SERPINB13 SERPINB3 SERPINB4

7.14e-0439843IPR000215
DomainSugar_P_trans_dom

SLC35E2A SLC35E2B

8.79e-0410842IPR004853
DomainDAGK_acc

DGKB DGKG

8.79e-0410842PF00609
DomainDiacylglycerol_kin_accessory

DGKB DGKG

8.79e-0410842IPR000756
DomainZU5

UNC5A UNC5D

8.79e-0410842PS51145
DomainDAGKa

DGKB DGKG

8.79e-0410842SM00045
DomainTPT

SLC35E2A SLC35E2B

8.79e-0410842PF03151
DomainZU5

UNC5A UNC5D

1.28e-0312842PF00791
DomainZU5_dom

UNC5A UNC5D

1.28e-0312842IPR000906
DomainSSD

NPC1L1 PTCH2

1.51e-0313842IPR000731
DomainSSD

NPC1L1 PTCH2

1.51e-0313842PS50156
DomainDAGKc

DGKB DGKG

1.76e-0314842SM00046
DomainDiacylglycerol_kinase_cat_dom

DGKB DGKG

2.02e-0315842IPR001206
DomainDAGK_cat

DGKB DGKG

2.02e-0315842PF00781
DomainDAGK

DGKB DGKG

2.02e-0315842PS50146
DomainNAD/diacylglycerol_kinase

DGKB DGKG

2.60e-0317842IPR016064
DomainAa_trans

SLC38A10 SLC36A1

2.60e-0317842PF01490
DomainAA_transpt_TM

SLC38A10 SLC36A1

2.60e-0317842IPR013057
Domain-

PTGR2 SORD

2.92e-03188423.90.180.10
DomainNA_NEUROTRAN_SYMP_2

SLC6A16 SLC6A14

2.92e-0318842PS00754
DomainFd_Rdtase_FAD-bd

DUOX2 CYB5R1

3.25e-0319842IPR017927
DomainADH_zinc_N

PTGR2 SORD

3.25e-0319842PF00107
DomainSNF

SLC6A16 SLC6A14

3.25e-0319842PF00209
DomainFAD_FR

DUOX2 CYB5R1

3.25e-0319842PS51384
DomainNA_NEUROTRAN_SYMP_1

SLC6A16 SLC6A14

3.25e-0319842PS00610
DomainNA_NEUROTRAN_SYMP_3

SLC6A16 SLC6A14

3.25e-0319842PS50267
DomainADH_SF_Zn-type

PTGR2 SORD

3.25e-0319842IPR002085
DomainADH_C

PTGR2 SORD

3.25e-0319842IPR013149
DomainNa/ntran_symport

SLC6A16 SLC6A14

3.25e-0319842IPR000175
DomainRiboflavin_synthase-like_b-brl

DUOX2 CYB5R1

3.25e-0319842IPR017938
DomainGroES-like

PTGR2 SORD

5.17e-0324842IPR011032
DomainEFh

DGKB DGKG DUOX2 ZZEF1

5.63e-03158844SM00054
DomainDEATH

UNC5A UNC5D

6.52e-0327842SM00005
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC9A8 SLC36A1 SLCO4C1 SLC39A3 SLC22A16 SLC2A7 SLC34A2 SLC26A1 SLC6A14

2.25e-06238699MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC9A8 SLC36A1 SLCO4C1 SLC39A3 SLC22A16 SLC2A7 SLC34A2 SLC26A1 SLC6A14

3.26e-06249699M5988
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC9A8 SLC36A1 SLC34A2 SLC26A1 SLC6A14

1.83e-04108695M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC9A8 SLC36A1 SLC34A2 SLC26A1 SLC6A14

1.91e-04109695MM15074
Pubmed

Comparative genomic analysis of the clade B serpin cluster at human chromosome 18q21: amplification within the mouse squamous cell carcinoma antigen gene locus.

SERPINB13 SERPINB3 SERPINB4

2.46e-061187315203215
Pubmed

The amplified mouse squamous cell carcinoma antigen gene locus contains a serpin (Serpinb3b) that inhibits both papain-like cysteine and trypsin-like serine proteinases.

SERPINB3 SERPINB4

6.19e-06287215203214
Pubmed

Increased Th1 immune response in SERPINB3 transgenic mice during acute liver failure.

SERPINB3 SERPINB4

6.19e-06287223354406
Pubmed

Serpin B4 isoform overexpression is associated with aberrant epithelial proliferation and lung cancer in idiopathic pulmonary fibrosis.

SERPINB3 SERPINB4

6.19e-06287222406480
Pubmed

Recurrent SERPINB3 and SERPINB4 mutations in patients who respond to anti-CTLA4 immunotherapy.

SERPINB3 SERPINB4

6.19e-06287227668655
Pubmed

SLC35E2 promoter mutation as a prognostic marker of esophageal squamous cell carcinoma.

SLC35E2A SLC35E2B

6.19e-06287235247439
Pubmed

Characterization of novel squamous cell carcinoma antigen-related molecules in mice.

SERPINB3 SERPINB4

6.19e-06287215504361
Pubmed

SCCA2-like serpins mediate genetic predisposition to skin tumors.

SERPINB3 SERPINB4

6.19e-06287212702576
Pubmed

Serpinb3 is overexpressed in the liver in presence of iron overload.

SERPINB3 SERPINB4

6.19e-06287228935635
Pubmed

Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins.

SERPINB3 SERPINB4

6.19e-06287235022507
Pubmed

Overexpression of SERPIN B3 promotes epithelial proliferation and lung fibrosis in mice.

SERPINB3 SERPINB4

6.19e-06287221403642
Pubmed

Structure-based mapping of DAF active site residues that accelerate the decay of C3 convertases.

CD55 CFB

6.19e-06287217395591
Pubmed

SERPINB3/B4 contributes to early inflammation and barrier dysfunction in an experimental murine model of atopic dermatitis.

SERPINB3 SERPINB4

6.19e-06287225111616
Pubmed

Molecular cloning of human squamous cell carcinoma antigen 1 gene and characterization of its promoter.

SERPINB3 SERPINB4

6.19e-06287211267667
Pubmed

Squamous Cell Carcinoma Antigen-encoding Genes SERPINB3/B4 as Potentially Useful Markers for the Stratification of HNSCC Tumours.

SERPINB3 SERPINB4

6.19e-06287229491058
Pubmed

Squamous cell carcinoma antigen production in nasal inverted papilloma.

SERPINB3 SERPINB4

6.19e-06287223168150
Pubmed

The serpin SQN-5 is a dual mechanistic-class inhibitor of serine and cysteine proteinases.

SERPINB3 SERPINB4

6.19e-06287211863458
Pubmed

IgM-linked SerpinB3 and SerpinB4 in sera of patients with chronic liver disease.

SERPINB3 SERPINB4

6.19e-06287222808225
Pubmed

Overexpression of squamous cell carcinoma antigen variants in hepatocellular carcinoma.

SERPINB3 SERPINB4

6.19e-06287214970861
Pubmed

Endoplasmic reticulum-associated degradation of Niemann-Pick C1: evidence for the role of heat shock proteins and identification of lysine residues that accept ubiquitin.

NPC1L1 HSPA8

6.19e-06287224891511
Pubmed

Co-expression of the squamous cell carcinoma antigens 1 and 2 in normal adult human tissues and squamous cell carcinomas.

SERPINB3 SERPINB4

6.19e-06287210653592
Pubmed

Serum squamous cell carcinoma antigen as an early indicator of response during therapy of cervical cancer.

SERPINB3 SERPINB4

6.19e-06287229112685
Pubmed

Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells.

SERPINB3 SERPINB4

6.19e-06287210956412
Pubmed

Tumor-related protein, the squamous cell carcinoma antigen binds to the intracellular protein carbonyl reductase.

SERPINB3 SERPINB4

6.19e-06287220428762
Pubmed

SerpinB3 as a Pro-Inflammatory Mediator in the Progression of Experimental Non-Alcoholic Fatty Liver Disease.

SERPINB3 SERPINB4

6.19e-06287235874657
Pubmed

The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease.

SERPINB3 SERPINB4 LAMP1

6.73e-061587330704515
Pubmed

Serpin B3/B4, activated by STAT3, promote survival of squamous carcinoma cells.

SERPINB3 SERPINB4

1.85e-05387219070595
Pubmed

A murine ortholog of the human serpin SCCA2 maps to chromosome 1 and inhibits chymotrypsin-like serine proteinases.

SERPINB3 SERPINB4

1.85e-0538729828132
Pubmed

Anti-apoptotic effects of SERPIN B3 and B4 via STAT6 activation in macrophages after infection with Toxoplasma gondii.

SERPINB3 SERPINB4

1.85e-05387222451727
Pubmed

A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene.

SERPINB3 SERPINB4

1.85e-0538727724531
Pubmed

Differentially expressed proteins in human breast cancer cells sensitive and resistant to paclitaxel.

SERPINB3 SERPINB4

1.85e-05387224898082
Pubmed

Taurine uptake across the human intestinal brush-border membrane is via two transporters: H+-coupled PAT1 (SLC36A1) and Na+- and Cl(-)-dependent TauT (SLC6A6).

SLC36A1 SLC6A14

1.85e-05387219074966
Pubmed

A nonredundant role for mouse Serpinb3a in the induction of mucus production in asthma.

SERPINB3 SERPINB4

1.85e-05387221126757
Pubmed

Diagnostic and prognostic role of SCCA-IgM serum levels in hepatocellular carcinoma (HCC).

SERPINB3 SERPINB4

1.85e-05387224635038
Pubmed

Heparin enhances serpin inhibition of the cysteine protease cathepsin L.

SERPINB3 SERPINB4

1.85e-05387219959474
Pubmed

Uteroglobin suppresses SCCA gene expression associated with allergic asthma.

SERPINB3 SERPINB4

1.85e-05387215677460
Pubmed

Emerging role for autophagy in the removal of aggresomes in Schwann cells.

LAMP1 HSPA8

3.70e-05487214627652
Pubmed

Serpin squamous cell carcinoma antigen inhibits UV-induced apoptosis via suppression of c-JUN NH2-terminal kinase.

SERPINB3 SERPINB4

3.70e-05487216549498
Pubmed

Inhibitory mechanism of a cross-class serpin, the squamous cell carcinoma antigen 1.

SERPINB3 SERPINB4

3.70e-05487212949073
Pubmed

Squamous cell carcinoma antigen 1 promotes caspase-8-mediated apoptosis in response to endoplasmic reticulum stress while inhibiting necrosis induced by lysosomal injury.

SERPINB3 SERPINB4

3.70e-05487221576355
Pubmed

Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases.

DGKB DGKG

6.16e-05587222627129
Pubmed

Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosis.

CLN3 LAMP1

6.16e-05587215588329
Pubmed

Retrovirus-mediated over-expression of decay-accelerating factor rescues Crry-deficient erythrocytes from acute alternative pathway complement attack.

CD55 CFB

6.16e-05587217015743
Pubmed

The collapsin response mediator protein 1 (CRMP-1) and the promyelocytic leukemia zinc finger protein (PLZF) bind to UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE), the key enzyme of sialic acid biosynthesis.

RIF1 ZBTB16

6.16e-05587217118363
Pubmed

ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection.

RIF1 ASTE1

9.22e-05687234354233
Pubmed

A role for Ly108 in the induction of promyelocytic zinc finger transcription factor in developing thymocytes.

SLAMF6 ZBTB16

1.29e-04787223355739
Pubmed

Cloning of three mouse Unc5 genes and their expression patterns at mid-gestation.

UNC5A UNC5D

1.29e-04787212351186
Pubmed

Peri-pubertal emergence of UNC-5 homologue expression by dopamine neurons in rodents.

UNC5A UNC5D

1.29e-04787220628609
Pubmed

Defining the membrane proteome of NK cells.

RCE1 NCAPG EIF4ENIF1 P2RX4 RECQL4 MFSD6 HLA-G LAMP1 AK6 HSPA8 CYB5R1

1.59e-041168871119946888
Pubmed

Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway.

CD55 CFB

1.72e-04887214670299
Pubmed

Macrophage MHC receptor 2: a novel receptor on allograft (H-2D(d)K(d))-induced macrophage (H-2D(b)K(b)) recognizing an MHC class I molecule, H-2K(d), in mice.

MFSD6 HLA-G

1.72e-04887217010536
Pubmed

Proteomic identification of exosomal LRG1: a potential urinary biomarker for detecting NSCLC.

SERPINB3 SORD

1.72e-04887221557262
Pubmed

Update of the human and mouse SERPIN gene superfamily.

SERPINB13 SERPINB3 SERPINB4

1.74e-044387324172014
Pubmed

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.

SERPINB3 SLC34A2 SLC6A14

2.12e-044687319190083
Pubmed

Familial pure proximal renal tubular acidosis--a clinical and genetic study.

SLC9A8 SLC26A1

2.20e-04987217881426
Pubmed

Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain.

UNC5A UNC5D

2.20e-04987223457482
Pubmed

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.

UNC5A PTCH2 CD55 UNC5D

2.90e-0412687416284245
Pubmed

The global gene-expression profiles of U-937 human macrophages treated with Tat peptide and Tat-FITC conjugate.

APOL6 HLA-G UPK3A

3.06e-045287322632162
Pubmed

Novel role for Netrins in regulating epithelial behavior during lung branching morphogenesis.

UNC5A UNC5D

3.35e-041187215186747
Pubmed

Analysis of Netrin 1 receptors during inner ear development.

UNC5A UNC5D

3.35e-041187217616930
Pubmed

VPS4B deficiency causes early embryonic lethality and induces signal transduction disorders of cell endocytosis.

LAMP1 HSPA8

3.35e-041187233682352
Pubmed

Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis.

CD55 CFB

3.35e-041187223204401
Pubmed

Diacylglycerol kinase delta regulates protein kinase C and epidermal growth factor receptor signaling.

DGKB DGKG

3.35e-041187217021016
Pubmed

Quantitative trait locus for seizure susceptibility on mouse chromosome 5 confirmed with reciprocal congenic strains.

SLC34A2 GNRHR

3.35e-041187217698926
Pubmed

Deficiency of decay-accelerating factor and complement receptor 1-related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg.

CD55 CFB

4.02e-041287218524992
Pubmed

An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program.

EIF4ENIF1 UNC5D

4.02e-041287225456498
Pubmed

SAP protein-dependent natural killer T-like cells regulate the development of CD8(+) T cells with innate lymphocyte characteristics.

ZBTB16 HLA-G

4.02e-041287220674402
Pubmed

Genome-wide association analysis identifies three psoriasis susceptibility loci.

SLC9A8 PRSS53

4.74e-041387220953189
Pubmed

Blocking properdin, the alternative pathway, and anaphylatoxin receptors ameliorates renal ischemia-reperfusion injury in decay-accelerating factor and CD59 double-knockout mice.

CD55 CFB

4.74e-041387223427256
Pubmed

Interleukin-32α modulates promyelocytic leukemia zinc finger gene activity by inhibiting protein kinase Cɛ-dependent sumoylation.

ZBTB16 HSPA8

4.74e-041387225178676
Pubmed

Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse.

SERPINB3 SERPINB4

4.74e-041387211863365
Pubmed

Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects.

SLC38A10 SLC36A1

6.36e-041587223506890
Pubmed

Muscle contraction is necessary to maintain joint progenitor cell fate.

CACNA1S MATN1

6.36e-041587219460349
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

RIF1 CLN3 NFRKB EIF5B NSMCE3 HSPA8 UNC5D CDH17

7.22e-0477487815302935
Pubmed

Programme of self-reactive innate-like T cell-mediated cancer immunity.

ZBTB16 HLA-G

7.26e-041687235444279
Pubmed

Tissue distribution, ontogeny, and hormonal regulation of xenobiotic transporters in mouse kidneys.

SLCO4C1 SLC34A2

7.26e-041687219679677
Pubmed

Activated Hedgehog-GLI Signaling Causes Congenital Ureteropelvic Junction Obstruction.

PTCH2 UPK3A

7.26e-041687229109083
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

RCE1 TPST1 PTPRS HYAL3 CD55 LAMP1 FUCA2 SLC43A3 ZZEF1 AMIGO2

8.36e-041201871035696571
Pubmed

Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons.

LAMP1 HSPA8

1.38e-032287227407143
Pubmed

Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate.

UNC5A UNC5D

1.38e-032287222726835
Pubmed

Recombination in the class III region of the mouse major histocompatibility complex.

HLA-G CFB

1.38e-03228727916002
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

P2RX4 PTPRS CD55 LAMP1 UPK3A FUCA2 HSPA8 CFB SORD

1.43e-03107087923533145
Pubmed

A genomic analysis of rat proteases and protease inhibitors.

SERPINB3 SERPINB4

1.51e-032387215060002
Pubmed

Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons.

UNC5A UNC5D

1.65e-032487226633881
Pubmed

NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy.

CD55 HSPA8

1.79e-032587230309841
Pubmed

Ubiquitin ligase MARCH5 localizes to peroxisomes to regulate pexophagy.

HSPA8 CYB5R1

1.79e-032587234747980
Pubmed

Differential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways.

CDC42EP3 HSPA8

1.79e-032587224947832
Pubmed

Host determinants of HIV-1 control in African Americans.

HLA-G CFB

1.93e-032687220205591
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

SLC9A8 SLCO4C1 SLC34A2 SLC6A14

2.01e-0321287419521566
Pubmed

Control of TurboID-dependent biotinylation intensity in proximity ligation screens.

SLC38A10 HYAL3 HLA-G

2.05e-0310087336966971
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SLC9A8 STXBP5L DTX4

2.17e-0310287310231032
Pubmed

N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.

SLC38A10 SLC35E2A TMEM170A SLC35E2B

2.19e-0321787434048709
Pubmed

Differential expression of paralog RNA binding proteins establishes a dynamic splicing program required for normal cerebral cortex development.

STXBP5L DGKB

2.24e-032887238324473
Pubmed

Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration.

PTCH2 UPK3A

2.40e-032987228049658
Pubmed

Proteomic and Interactome Approaches Reveal PAK4, PHB-2, and 14-3-3η as Targets of Overactivated Cdc42 in Cellular Responses to Genomic Instability.

SERPINB3 HLA-G EIF5B CDC42EP3

2.50e-0322587431478661
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

RCE1 SLC38A10 SLC22A16 RECQL4 HLA-G ZZEF1 HSPA8

2.50e-0373687729676528
Cytoband18q21.3

SERPINB3 SERPINB4

1.93e-041187218q21.3
GeneFamilySolute carriers

SLC9A8 SLC38A10 SLC36A1 SLCO4C1 SLC39A3 SLC22A16 SLC6A16 SLC2A7 SLC35E2A SLC34A2 SLC43A3 SLC35E2B SLC26A1 SLC6A14 SLC22A31

2.68e-123956115752
GeneFamilySerpin peptidase inhibitors

SERPINB13 SERPINB3 SERPINB4

2.62e-0437613739
GeneFamilyEF-hand domain containing|Diacylglycerol kinases

DGKB DGKG

4.95e-04106121178
CoexpressionGSE37301_LYMPHOID_PRIMED_MPP_VS_CD4_TCELL_UP

SLC36A1 SLC6A16 NPC1L1 SLC34A2 DUOX2 SLC35E2B GNRHR

3.54e-06196857M8858
ToppCell(05)_Secretory|World / shred by cell type by condition

SERPINB3 SERPINB4 DTX4 CD55 SLC34A2 ERN2 CFB SLC6A14

4.89e-091968788032c25b51ef96aeba28cc52686a2bd45213453d
ToppCellBL-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SERPINB13 SERPINB3 SERPINB4 DTX4 ERN2 CFB SLC6A14

9.42e-08190877f2abe4bc28e934287e2dcd7b9399d5af78c5c8cf
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 SERPINB4 CD55 DUOX2 ERN2 CFB SLC6A14

9.76e-08191877529068029fb461df766135576dd0d8b5980f9bc0
ToppCellNS-critical-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SERPINB3 SERPINB4 DTX4 ERN2 CFB SLC6A14 SORD

1.21e-07197877a72047b7428c0d4aaf016c1ac23dc30919260fd8
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 CD55 DUOX2 ERN2 CFB SLC6A14 SORD

1.29e-071998778bf8d7cd774479f065bbbbcb5a4bd1aa91aa0d85
ToppCelldistal-2-Epithelial-Mucous|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB3 SERPINB4 SLC34A2 ERN2 CFB SLC6A14 SORD

1.29e-07199877c0275b5011c2bb08e873955afe2e213ec8070d0e
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 CD55 DUOX2 ERN2 CFB SLC6A14 SORD

1.29e-071998770c060ef64341659f4b1247d0264ac12e53a7e12e
ToppCellcontrol-Epithelial-Secretory|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RIF1 SLCO4C1 PTPRS DTX4 LAMP1 ERN2 SORD

1.29e-07199877262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SERPINB13 SERPINB3 SERPINB4 CD55 SLC6A14 SORD

1.08e-0617187625c1979e972c959e1ce4c57804f976f53a247ad7
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SERPINB13 SERPINB3 SERPINB4 CD55 SLC6A14 SORD

1.08e-06171876fe27bf581c75ef33c2848878e51ed16b275a4c8e
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SERPINB13 SLCO4C1 SERPINB3 ERN2 CFB SLC6A14

1.16e-06173876d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCell18-Airway-Epithelial-Club-like_secretory|Airway / Age, Tissue, Lineage and Cell class

SERPINB13 SLCO4C1 SERPINB3 SERPINB4 ERN2 SLC6A14

1.82e-06187876d1e301afcc39054ae1f867d80e564e30a137e3f8
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 DTX4 APOL6 DUOX2 ERN2 SLC6A14

1.99e-061908766ea9fa08bd97bedcb21d3654467e7f8dd74c8fd0
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 SERPINB4 CD55 ERN2 CFB SLC6A14

1.99e-0619087623f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 SERPINB4 CD55 ERN2 CFB SLC6A14

1.99e-061908763c337374d89e69cc0a78e65a4a7e21db7b050fcd
ToppCellNS-critical-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTPRS SERPINB3 DTX4 ERN2 CFB SORD

2.25e-061948762172d951896265243d14996eacce5aab5e14e26e
ToppCellNasal_Brush|World / Tissue, Lineage and Cell class of Lung Cells from 10X

SERPINB3 SERPINB4 DUOX2 ERN2 SLC6A14 SORD

2.31e-061958767509b980b6b293df02bec619ef5b83a6c7b49c03
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 SERPINB4 CD55 DUOX2 SLC6A14 SORD

2.31e-061958763f8ed20ad17afe1545e574e5ca5fe33c3704c7f3
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 SERPINB4 CD55 ERN2 CFB SLC6A14

2.38e-061968762c3fbfbb08cd327cd97b3fa5a6f83b6d50771fb7
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 SERPINB4 CD55 ERN2 CFB SLC6A14

2.38e-06196876a52879a4c822c5e4be569f01f845a795e00c5f4b
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 SERPINB4 CD55 ERN2 CFB SLC6A14

2.38e-061968767a4d502550e9e37dc42f2ff1be3c896afe365d7f
ToppCellNS-moderate-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DTX4 DUOX2 ERN2 CFB SLC6A14 SORD

2.38e-0619687647930de6b47b7bf22d8dae8b7419a9cd1d22f0ea
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 SERPINB4 CD55 ERN2 CFB SLC6A14

2.38e-0619687660ea673ed887fe3890c5cf4ff4165384b76d7361
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 CD55 DUOX2 ERN2 CFB SLC6A14

2.46e-06197876adb4e27d73ae2e6a39d212c0ead3ac0ad62d9131
ToppCellproximal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB13 SERPINB3 SERPINB4 ERN2 CFB SORD

2.53e-061988763477202c4f702d8f75231b13d4b5216f56d981d7
ToppCellproximal-Epithelial-Goblet|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB13 SERPINB3 SERPINB4 ERN2 CFB SORD

2.53e-06198876e7e1c430486a81280abc4a7e7f5bc3713dd20737
ToppCellBL-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SERPINB3 SERPINB4 DUOX2 ERN2 SLC6A14 SORD

2.53e-06198876484d16aaa601a1e11b871b0475dd01a2de1a29ce
ToppCellproximal-Epithelial-Goblet-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB13 SERPINB3 SERPINB4 ERN2 CFB SORD

2.53e-06198876da7b40eb00bb5e454e1cfcd1219dc0d84712592a
ToppCellmedial-2-Epithelial-Mucous|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB3 SERPINB4 ERN2 CFB SLC6A14 SORD

2.60e-061998764737250b7ffa7cc19eb6b057d35d78f13b1afe66
ToppCellmedial-Epithelial-Mucous|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB3 SERPINB4 ERN2 CFB SLC6A14 SORD

2.60e-061998764385963ab25b5378e7964b984028c25b27e5794e
ToppCellNS-control-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SLCO4C1 PTPRS DTX4 LAMP1 ERN2 SORD

2.60e-0619987632bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SERPINB13 SERPINB3 SERPINB4 ERN2 CFB SLC6A14

2.60e-061998763c3133d0aa65338a576634def13e7f0f5c573a10
ToppCell(04)_Interm._basal>secr.|World / shred by cell type by condition

SERPINB3 SERPINB4 DTX4 CD55 CFB SLC6A14

2.60e-06199876ed399244433f781fc291a9bff16825b8a3ca294f
ToppCellcontrol-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RIF1 SLCO4C1 PTPRS LAMP1 ERN2 SORD

2.60e-061998763d01f90ffd271ca00129192787e4921bdca7e01e
ToppCellBiopsy_IPF-Epithelial-MUC5AC+_High|Biopsy_IPF / Sample group, Lineage and Cell type

SERPINB13 SERPINB3 SERPINB4 ERN2 CFB SLC6A14

2.60e-0619987651cb306e36537a53968c55187bd87c83e1706187
ToppCelldistal-Epithelial-Mucous-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB3 SERPINB4 ERN2 CFB SLC6A14 SORD

2.60e-061998760af89ef40807fc4ad79ab82a2186ab6e866c6931
ToppCellmedial-Epithelial-Mucous-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB3 SERPINB4 ERN2 CFB SLC6A14 SORD

2.60e-0619987653198bcf5f2f012a3ed1600d95c0923d6976a099
ToppCelldistal-Epithelial-Mucous|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB3 SERPINB4 ERN2 CFB SLC6A14 SORD

2.60e-06199876a7fe7b792d696f369ad0310a772160a1729ef223
ToppCellmoderate-Epithelial-Secretory-diff|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SERPINB3 SERPINB4 CD55 DUOX2 SLC6A14 SORD

2.68e-062008766f29ef9dcf126c5c19386f6aa9a20c38a2c8ccc8
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_basal-Suprabasal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SERPINB13 SERPINB3 SERPINB4 ERN2 SLC6A14 SORD

2.68e-062008765f0f67958c9635db53e61f8370a92da6ea3e80fe
ToppCellNS-moderate-d_16-33-Epithelial-Secretory-diff|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SERPINB3 SERPINB4 CD55 DUOX2 SLC6A14 SORD

2.68e-062008768f179b5768fd504af6dd6f6749a0bed7b689e77f
ToppCellParenchyma_COVID-19-Epithelial-TX-Club|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

SERPINB3 SERPINB4 DTX4 CD55 SLC34A2 ERN2

2.68e-0620087685f946dd3831acf3488c87efba96689cc2667c3a
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SERPINB3 CD55 SLC34A2 ERN2 SLC6A14 SORD

2.68e-062008768f811ddd84c037a250d124496b0fbb2e4717011c
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SERPINB3 SERPINB4 DTX4 CD55 SLC34A2 ERN2

2.68e-062008768a44a4f7ea9358f2194a490e79601c98ff7fdcb0
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Club|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SERPINB3 SERPINB4 DTX4 CD55 SLC34A2 ERN2

2.68e-0620087630d428510c68da96c7c8cfd472f449ebb9631132
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Metaplastic_Carcinoma-4|TCGA-Breast / Sample_Type by Project: Shred V9

SERPINB13 SLCO4C1 SERPINB3 SERPINB4 SLC6A14

4.35e-0612387511802979943a9205f10facda322fc220d4bf7133
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Metaplastic_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

SERPINB13 SLCO4C1 SERPINB3 SERPINB4 SLC6A14

4.35e-0612387551e49a64fbbf77e2ee21f45fd515d43282b11516
ToppCellNS-moderate-d_07-13-Epithelial-IRC-IFNG_responsive_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SERPINB3 SERPINB4 CD55 SLC34A2 SLC6A14

7.10e-061368757f1ca43e0d164b511120316d4218d80ba21a9b5c
ToppCellClub_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

SERPINB13 SERPINB3 SERPINB4 ERN2 SORD

1.11e-0514987581c813588bb5efb7b31141a75d387210dcb76094
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 CD55 ERN2 CFB SLC6A14

1.51e-0515987560b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 CD55 DGKG DUOX2 GPAT2

1.66e-05162875c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 CD55 DGKG DUOX2 GPAT2

1.66e-05162875f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 CD55 DGKG DUOX2 GPAT2

1.66e-051628755d902bb31e691aea9749617cc88303c2448f24b8
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Calb2|Hippocampus / BrainAtlas - Mouse McCarroll V32

APOL6 PTCH2 PKHD1L1 AMIGO2

1.75e-057987403c5af851b53800eced1c74e9da374c71092bcd4
ToppCellNS-critical-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DTX4 SLC34A2 ERN2 CFB SORD

2.03e-05169875aec97583b23112060437b619cb429dc32f29285f
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.4|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 CD55 DUOX2 CFB SLC6A14

2.27e-05173875176b956e71d98e8275d698b39437fc326e5fe449
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCAPG SERPINB13 SERPINB3 SERPINB4 SLC6A14

2.34e-05174875207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S TPST1 P2RX4 UPK3A AMIGO2

2.82e-0518187597022416d0f5a5ba9c9bd5e70ce95cf4cb19af89
ToppCellControl-Myeloid-DC1|Control / Condition, Lineage and Cell class

ARHGAP42 TPST1 EGR3 RDH5 CDH17

2.82e-051818755a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC5A EGR3 APBA1 TM4SF4 AMIGO2

2.90e-05182875398ce074a04f6482470b488f1affae4af7d2ec58
ToppCellPSB-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SERPINB3 SERPINB4 CD55 DUOX2

3.07e-05918749c61b9f3e9e4f0c9cb242e313d642c2b75705c88
ToppCellCOPD-Epithelial-Goblet|World / Disease state, Lineage and Cell class

ARHGAP42 SERPINB3 SERPINB4 ERN2 SLC6A14

3.21e-05186875d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Pulmonary_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

STXBP5L NPC1L1 DGKB UNC5D AMIGO2

3.21e-05186875fcabebdfbf1b1dbb35ce2b3c53a60d2b1aed8e6c
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTF2 SERPINB3 SLC35E2B CYB5R1 SORD

3.30e-05187875f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SERPINB3 DTX4 ERN2 CFB SORD

3.47e-05189875b06471b1bebb990d5146bddfb8002401c6b099a0
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|343B / Donor, Lineage, Cell class and subclass (all cells)

SERPINB3 DTX4 ERN2 CFB SORD

3.47e-05189875a8246acf31f02c85421268245afb651aa8788f14
ToppCellIPF-Epithelial-Goblet|IPF / Disease state, Lineage and Cell class

ARHGAP42 SERPINB3 SLC34A2 ERN2 SLC6A14

3.56e-05190875e41dd5a997ad9952810ffecb57737c03ea1d88b3
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZBTB16 SLCO4C1 CD55 SLC34A2 SLC22A31

3.74e-0519287529f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCellCOPD-Epithelial-Goblet|COPD / Disease state, Lineage and Cell class

ARHGAP42 SERPINB3 SERPINB4 ERN2 SLC6A14

3.74e-0519287593b2ca0a97776d28c7e8f1a0642c4b63a5554aab
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 SERPINB4 CD55 SLC6A14 SORD

3.83e-05193875463274f394757fb2570ae885d58e1f9fa7e60c4a
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

EGR3 SERPINB3 SERPINB4 CD55 SLC34A2

3.83e-05193875ca7c0a4ceb05bced90f6cdc53d278e547fb241e9
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SERPINB3 DTX4 ERN2 CFB SORD

3.83e-051938758ede7038a222c7e7ecaf7e86520823cf606cbee7
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SERPINB3 DTX4 ERN2 CFB SORD

3.83e-051938750e7d7adfaa7191e34038fcda6677561ae13934eb
ToppCelldistal-Epithelial-Differentiating_Basal-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB13 PTPRS SERPINB3 SERPINB4 ERN2

4.02e-051958753fe6e49a9161fc9e5160251e6932cb5378175a54
ToppCellNS-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SERPINB3 DUOX2 ERN2 CFB SLC6A14

4.02e-05195875b0d782eeee30c797b4da9b3be29b864983fd9e71
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 CD55 ERN2 CFB SLC6A14

4.02e-051958756095bb237d7bc75cbaeaeb492f6948f3c3fa4848
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 CD55 ERN2 CFB SLC6A14

4.12e-05196875c18874f37b90e6afacc562b2082b67ea8a7cb4a4
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|COVID-19 / Condition, Lineage and Cell class

SERPINB13 SERPINB3 SERPINB4 ERN2 SLC6A14

4.12e-05196875dd32046067d93b9484cfbf1d7826a436a3d9f0e9
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 SERPINB4 DUOX2 ERN2 SORD

4.12e-051968755789b5b0763d6eab21bf4da1fd8eae6116f46f3f
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Club|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP42 DTX4 CD55 SLC34A2 SLC22A31

4.12e-05196875d5f9168001e60bafec17fe6c702e68f5528edc20
ToppCellcritical-Epithelial-Secretory|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SERPINB3 ERN2 CFB SLC6A14 SORD

4.12e-051968757da687eb983a54c28ee990424cc52e01caf5f4aa
ToppCellcritical-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SERPINB3 LAMP1 ERN2 CFB SORD

4.12e-05196875dbf14f5851c2b779a8b35e820c4584ea9096e49d
ToppCelldistal-3-Epithelial-Proximal_Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB13 SERPINB3 SERPINB4 DUOX2 ERN2

4.12e-051968757e1a565dd2da4f375cbce8842ba4fd6c22ac8375
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 SERPINB4 DUOX2 ERN2 SORD

4.12e-051968758e96fc87812d112ccae6e2ca1821bee1ee2efe48
ToppCellBronchial_Biopsy-Epithelial-Club|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

SLCO4C1 SERPINB3 CD55 ERN2 SLC6A14

4.12e-05196875057d150bdf0cad959fd03ec2d1560a96ba03fae9
ToppCelldistal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB13 SERPINB3 SERPINB4 ERN2 CFB

4.22e-05197875a00784ccfb1de6a96b91e2a8a2889b69f31a33da
ToppCellBronchial_Biopsy-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SLCO4C1 SERPINB3 CD55 ERN2 SLC6A14

4.22e-051978753f5dfa892a1f631b96eeb6f4cfc284aee51d1ce6
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CELF5 NCAPG SERPINB13 SERPINB3 RECQL4

4.22e-0519787525bbe270d0897b9b1bd00d205f66efd1def81b99
ToppCellBronchus_Control_(B.)|World / Sample group, Lineage and Cell type

SERPINB13 EGR3 SERPINB3 SERPINB4 ERN2

4.22e-05197875b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCellBiopsy_Other_PF-Epithelial-MUC5AC+_High|Biopsy_Other_PF / Sample group, Lineage and Cell type

SERPINB13 SERPINB3 SERPINB4 ERN2 CFB

4.33e-0519887530e6177e216f66caddcd009fafef0e07369f4d8e
ToppCellmoderate-Epithelial-Secretory|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DUOX2 ERN2 CFB SLC6A14 SORD

4.33e-051988757d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB13 SERPINB3 SERPINB4 ERN2 SLC6A14

4.33e-051988753cc9e671f596ef0829684018e4257571fefb6267
ToppCellmoderate-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

LAMP1 ERN2 CFB SLC6A14 SORD

4.33e-051988757ecce5e266bb08797088cc8f8309e0c7b48df5c9
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SERPINB13 SERPINB3 SERPINB4 DTX4 ERN2

4.33e-051988755dd2aa7684c36beffa204ca4c04d0501cabac10f
ToppCellNS-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SERPINB3 DUOX2 ERN2 SLC6A14 SORD

4.33e-051988754a481e1edb80b950c823ed926842cd5132cfb27f
ToppCellNS-critical-d_0-4-Epithelial-IRC-IFNG_responsive_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SERPINB3 SERPINB4 DUOX2 CFB SLC6A14

4.33e-05198875cf612c09a782b6ddc17e723865b8c0c7ddb19761
ToppCellNS-moderate-d_07-13-Epithelial-Secretory-diff|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SERPINB3 SERPINB4 CD55 SLC6A14 SORD

4.33e-05198875361f3062f73a0add16dd6fbe927698416515879f
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NCAPG SERPINB13 SERPINB3 SERPINB4 RECQL4

4.33e-05198875f088badb90c6c2d916195f5649eda102119c9ac6
ToppCellproximal-Epithelial-Differentiating_Basal-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB13 SERPINB3 SERPINB4 ERN2 SORD

4.43e-05199875c607346f60e5997e757e5a31cab412ab3734377b
ToppCellLPS_IL1RA_TNF-Hematopoietic_Erythro-Megakary|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NCAPG SLC22A16 HYAL3 HECTD4 PKHD1L1

4.43e-05199875f894c88ecc7fd0edca28587801fa59352d10f750
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

TM4SF4 DUOX2 CDH17 CES2

9.51e-0550524GAVISH_3CA_MALIGNANT_METAPROGRAM_30_PDAC_CLASSICAL
Drugsodium

CACNA1S SLC9A8 SLC36A1 P2RX4 SLC22A16 SLC6A16 CLN3 SLC2A7 SLC34A2 DUOX2 GCDH SLC43A3 SLC26A1 CFB SLC6A14

1.96e-069448515CID000000923
Diseaseinsulin metabolic clearance rate measurement, glucose homeostasis measurement

SLC22A16 SLC43A3 ZZEF1

7.92e-0614843EFO_0006830, EFO_0006896
Diseaseneutrophil measurement

SLC36A1 ZBTB16 SLCO4C1 HYAL3

1.66e-03177844EFO_0803548
Diseaseglucose metabolism disease (implicated_via_orthology)

DGKB DGKG

2.88e-0328842DOID:4194 (implicated_via_orthology)
Diseaseeosinophil measurement

SLC36A1 HYAL3 SLC43A3

3.66e-03108843EFO_0803540
DiseaseComplement deficiency disease

CD55 CFB

3.99e-0333842C0272242
Diseaserefractive error, self reported educational attainment

CD55 RDH5

4.23e-0334842EFO_0004784, MONDO_0004892
Diseasecervical cancer (is_marker_for)

CD55 HSPA8

4.74e-0336842DOID:4362 (is_marker_for)
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CACNA1S SLC6A14

4.74e-0336842DOID:11723 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
LIFIGGVPRSGTTLM

TPST1

71

O60507
LPLILVAMGLVIAGG

BTNL10

256

A8MVZ5
LIPLMVGLGLSASTV

nan

391

Q9N2K0
LIPLMVGLGLSASTI

nan

391

Q9N2J8
VISGVMSLLGLALAP

APOL6

86

Q9BWW8
LLMITVTVGPGASGV

AMIGO2

26

Q86SJ2
VLVGLGSEMTTVPLL

SORD

271

Q00796
LAGITGILMSAAGLP

DTX4

331

Q9Y2E6
AISLPTIGGSQALML

CDC42EP3

106

Q9UKI2
TMLVGPLIAIINSPG

ASTE1

491

Q2TB18
DIIPTMINIGSGLAL

P2RX4

331

Q99571
MLLPNILLTGTPGVG

AK6

1

Q9Y3D8
LMPFILGLLSGGVTT

CFB

11

P00751
SSLPTIPIMGIVAGL

HLA-G

301

P17693
GGNLLILVAVASMPS

OR10AC1

41

Q8NH08
IQPLSTGTMTGLAIQ

MATN1

111

P21941
TGVPKTGLLMTVLGI

MAGEB10

196

Q96LZ2
GLGRNIILTTMPAGT

NFRKB

1216

Q6P4R8
VSMFPLGGLLGSLLV

SLC2A7

81

Q6PXP3
MGLLLTVDPGSGTVL

ERN2

206

Q76MJ5
TLTGLLGTLVTMGLL

CD55

366

P08174
TVPGMTGVLLLLVLA

DUOX2

1186

Q9NRD8
ELTGIQPGTSLLTLM

RCE1

91

Q9Y256
IMESGVALLPGLIAS

CES2

251

O00748
RAGLGSIIPLQLLTM

HECTD4

3841

Q9Y4D8
LGMSPSQSGLLVGIR

MFSD6

96

Q6ZSS7
SVVGPMGLLVVLLVG

PTPRS

11

Q13332
AGVAMTNLPGILVLG

NPC1L1

1241

Q9UHC9
TGFIMLRNGLLTIPV

OR56B4

151

Q8NH76
VHGGMTTIPLLVLLG

DGKG

246

P49619
GNLLMNIGPTLDGTI

FUCA2

331

Q9BTY2
IPLMQGNLPTLTLSG

GNRHR

21

P30968
IISEMGELGVLGPTI

GCDH

96

Q92947
ILLVESGAMTPLGIS

CACNA1S

511

Q13698
NIISLMSAGILGVPP

EGR3

101

Q06889
MVGQLGILTPSLTLP

CELF5

226

Q8N6W0
MTTQLGPALVLGVAL

HYAL3

1

O43820
GILLPFMLLSQGLGV

GPAT2

211

Q6NUI2
QGGMTTIPLLVLLGL

DGKB

221

Q9Y6T7
IMSINGTSLVGLPLS

APBA1

706

Q02410
SMLIPIAVGGALAGL

LAMP1

381

P11279
GIPTVGMAVGILLTT

CDH17

781

Q12864
GMAVGILLTTLLVIG

CDH17

786

Q12864
PVLLLGTMVTGLASL

SLC22A31

396

A6NKX4
LSVVFGTMVGGILIP

SLC38A10

326

Q9HBR0
GTMVGGILIPNVETI

SLC38A10

331

Q9HBR0
VTPLSLGIETAGGVM

HSPA8

396

P11142
SSAIGIMQGIITPLQ

SLC6A16

511

Q9GZN6
TPLMVNGILGESVTL

SLAMF6

26

Q96DU3
LMTVSNLGVIFGPTL

ARHGAP42

526

A6NI28
GLMVITGSESPIVLL

SEC11B

26

P0C7V7
SNLGGMATIPSIQLL

RIF1

416

Q5UIP0
VLMLTPEALVGAGGL

RECQL4

576

O94761
ILLMGIVGPITAGIL

TMEM170A

86

Q8WVE7
GTMALLSGVLTLKLP

SLC22A16

511

Q86VW1
LPGMGTTIDVILING

EIF5B

866

O60841
PVTDGAISTLLGLLM

PTCH2

1061

Q9Y6C5
ILSLLGGEPSMLGAV

SLC35E2A

96

P0CK97
VSAMIPLGIGLGLGI

SLC39A3

236

Q9BRY0
VLFTILLLGGSTMPL

SLC9A8

456

Q9Y2E8
PMLTIGGILFLITNL

SLC43A3

131

Q8NBI5
MGIQTSPVLLASLGV

CYB5R1

1

Q9UHQ9
NTMGPIGVTLALLPL

RDH5

136

Q92781
PISITSALGMVLLGA

SERPINB3

31

P29508
GTSLGMVLIISLNLP

STXBP5L

856

Q9Y2K9
GLMGSLEPTTSLLGQ

EIF4ENIF1

546

Q9NRA8
GTAIQVAGIGVLPML

CLDN34

176

H7C241
GLSPQQTLLSMLGIP

CLN3

206

Q13286
MNGIIESLILPGIIS

NCAPG

581

Q9BPX3
NSSIMSNPLLGLVIG

SLC34A2

136

O95436
GPVLLIAGATVLMEG

PRSS53

6

Q2L4Q9
LSGTIPVQMLLEIGL

ZWILCH

411

Q9H900
LMTIGQSLLQGTLQP

ZBTB16

206

Q05516
TLGGIGLVTVGIMSI

TLCD2

201

A6NGC4
GIVMGPISLLIIGIV

SLC36A1

76

Q7Z2H8
GDVMSGLVIGIILVP

SLC26A1

71

Q9H2B4
PVGILTAIGMVLLGT

SERPINB13

31

Q9UIV8
GIQFMVLRLLGTIPG

SLCO4C1

616

Q6ZQN7
VLGATEPLTSGQLLM

SPATA20

416

Q8TB22
GGMIVITSILGSLPF

UPK3A

206

O75631
PISITSALGMVLLGA

SERPINB4

31

P48594
ILSLLGGEPSMLGAV

SLC35E2B

96

P0CK96
GLLVNLSLIPVMGGL

SLC35E2B

196

P0CK96
STPILKMLLIQGGTL

PKHD1L1

2211

Q86WI1
LGGRLVMPNTGVSLL

UNC5D

551

Q6UXZ4
QGTPTTGLLMIVLGL

NSMCE3

171

Q96MG7
GGRLMIPNTGISLLI

UNC5A

451

Q6ZN44
LLMLSGAPGEVGSVL

ZZEF1

946

O43149
LPLFQGVGITMVLIS

SLC6A14

111

Q9UN76
GAIGMPGLTSLIGIQ

PTGR2

131

Q8N8N7
GILGSGVLMIFPALV

TM4SF4

51

P48230
NGLLIGTTGVMLQSP

SOCS6

286

O14544
PQVMLISLLAGGVGL

TTF2

1061

Q9UNY4