Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncell adhesion molecule binding

FLNA ITGA11 OBSCN ITGA2B EHD4 CADM1 PTPRF DCHS1 TLN2 KDR SCRIB PLEC DHX29 CNTN1

1.79e-0559912214GO:0050839
GeneOntologyCellularComponentanchoring junction

FLNA ITGA11 OBSCN RPS16 SORBS1 ITGA2B THSD1 PIKFYVE RASIP1 HEPACAM CADM1 RANGRF MDC1 TLN2 PPP1R9B KDR SCRIB PLEC TBCD

3.31e-0697612119GO:0070161
GeneOntologyCellularComponentmitochondrial prohibitin complex

PHB2 PHB1

3.32e-0521212GO:0035632
GeneOntologyCellularComponentaxon

FLNA PRSS12 PHB2 PLXND1 DCTN1 ADCY8 HEPACAM CADM1 ADRB2 HMCN2 PTPRF AP3B2 PPP1R9B PLEC CNGB1 CNTN1

5.61e-0589112116GO:0030424
GeneOntologyCellularComponentcell-cell junction

FLNA OBSCN SORBS1 PIKFYVE RASIP1 HEPACAM CADM1 RANGRF TLN2 PPP1R9B SCRIB TBCD

1.66e-0459112112GO:0005911
GeneOntologyCellularComponentplasma membrane raft

PRTN3 SORBS1 ADCY8 ADRB2 RANGRF ATP2B4

2.16e-041471216GO:0044853
GeneOntologyCellularComponentmembrane raft

PRTN3 SORBS1 ADCY8 PIKFYVE ADRB2 RANGRF KDR ATP2B4 ATP5F1A

2.61e-043621219GO:0045121
GeneOntologyCellularComponentmembrane microdomain

PRTN3 SORBS1 ADCY8 PIKFYVE ADRB2 RANGRF KDR ATP2B4 ATP5F1A

2.72e-043641219GO:0098857
GeneOntologyCellularComponentglutamatergic synapse

FLNA PRSS12 PHB2 PLXND1 SYT10 ADCY8 PHB1 CADM1 ADRB2 MIB1 PLEKHA5 SCRIB ATP2B4 CNTN1

2.73e-0481712114GO:0098978
GeneOntologyCellularComponentpostsynaptic density

PHB2 ADCY8 PHB1 CADM1 PTPRF MIB1 TRAPPC4 PLEKHA5 PPP1R9B SCRIB

2.97e-0445112110GO:0014069
GeneOntologyCellularComponentcluster of actin-based cell projections

FLNA TSPEAR CUBN ADCY6 LOXHD1 PCDH15 PLEC

3.23e-042231217GO:0098862
GeneOntologyCellularComponentasymmetric synapse

PHB2 ADCY8 PHB1 CADM1 PTPRF MIB1 TRAPPC4 PLEKHA5 PPP1R9B SCRIB

4.61e-0447712110GO:0032279
GeneOntologyCellularComponentcaveola

SORBS1 ADCY8 ADRB2 RANGRF ATP2B4

4.70e-041111215GO:0005901
GeneOntologyCellularComponentpresynapse

PRSS12 PHB2 RPS16 SYT10 ADCY8 PHB1 CADM1 SLC35D3 AP3B2 TRAPPC4 SCRIB CNGB1 ATP2B4 CNTN1

6.13e-0488612114GO:0098793
GeneOntologyCellularComponentstereocilium

TSPEAR ADCY6 LOXHD1 PCDH15

6.91e-04691214GO:0032420
GeneOntologyCellularComponentpostsynaptic specialization

PHB2 ADCY8 PHB1 CADM1 PTPRF MIB1 TRAPPC4 PLEKHA5 PPP1R9B SCRIB

6.94e-0450312110GO:0099572
GeneOntologyCellularComponentfocal adhesion

FLNA ITGA11 RPS16 SORBS1 ITGA2B THSD1 MDC1 TLN2 PLEC

9.15e-044311219GO:0005925
GeneOntologyCellularComponentneuron to neuron synapse

PHB2 ADCY8 PHB1 CADM1 PTPRF MIB1 TRAPPC4 PLEKHA5 PPP1R9B SCRIB

9.34e-0452312110GO:0098984
GeneOntologyCellularComponentcell-substrate junction

FLNA ITGA11 RPS16 SORBS1 ITGA2B THSD1 MDC1 TLN2 PLEC

1.11e-034431219GO:0030055
GeneOntologyCellularComponentstereocilium bundle

TSPEAR ADCY6 LOXHD1 PCDH15

1.15e-03791214GO:0032421
GeneOntologyCellularComponentpresynaptic active zone

PHB2 ADCY8 PHB1 TRAPPC4 ATP2B4

1.38e-031411215GO:0048786
GeneOntologyCellularComponentmyelin sheath

PHB1 ASS1 SCRIB PLEC ATP5F1A CNTN1

1.67e-032171216GO:0043209
GeneOntologyCellularComponentZ disc

FLNA OBSCN HRC PLEC ATP2B4

1.87e-031511215GO:0030018
GeneOntologyCellularComponentsynaptic membrane

ADCY8 PHB1 CADM1 ADRB2 PTPRF TRAPPC4 PPP1R9B SCRIB ATP2B4 CNTN1

2.09e-0358312110GO:0097060
GeneOntologyCellularComponentSchaffer collateral - CA1 synapse

PRSS12 ADCY8 CADM1 ADRB2 ROCK1

2.09e-031551215GO:0098685
GeneOntologyCellularComponentcell-cell contact zone

OBSCN RANGRF TLN2 SCRIB

2.18e-03941214GO:0044291
GeneOntologyCellularComponentpostsynapse

FLNA PHB2 RPS16 ADCY8 PHB1 CADM1 ADRB2 PTPRF MIB1 TRAPPC4 PLEKHA5 PPP1R9B SCRIB CNTN1

2.29e-03101812114GO:0098794
GeneOntologyCellularComponentI band

FLNA OBSCN HRC PLEC ATP2B4

2.82e-031661215GO:0031674
GeneOntologyCellularComponentcytoplasmic vesicle membrane

ITGA2B CUBN THSD1 SYT10 ADCY8 EHD4 SCARF1 PIKFYVE ADRB2 CD33 NBEAL2 SLC35D3 AP3B2 CNGB1 TAP2 DSE

3.57e-03130712116GO:0030659
GeneOntologyCellularComponentcollagen-containing extracellular matrix

COL9A2 PRTN3 DSPP CCDC80 COL22A1 SSPOP HMCN2 LOXL3 SOD3

3.72e-035301219GO:0062023
DomainProhibitin

PHB2 PHB1

4.16e-0521212IPR000163
DomainIg_I-set

OBSCN HEPACAM CADM1 HMCN2 PTPRF KDR CNTN1

2.40e-041901217IPR013098
DomainI-set

OBSCN HEPACAM CADM1 HMCN2 PTPRF KDR CNTN1

2.40e-041901217PF07679
DomainMib_Herc2

MIB2 MIB1

2.48e-0441212IPR010606
DomainMIB_HERC2

MIB2 MIB1

2.48e-0441212PS51416
DomainMIB_HERC2

MIB2 MIB1

2.48e-0441212PF06701
Domain-

RPS16 FCSK GFM1

3.24e-042112133.30.230.10
DomainRibosomal_S5_D2-typ_fold_subgr

RPS16 FCSK GFM1

3.73e-04221213IPR014721
DomainAdcy_conserved_dom

ADCY6 ADCY8

6.14e-0461212IPR009398
DomainDUF1053

ADCY6 ADCY8

6.14e-0461212PF06327
DomainIGc2

OBSCN HEPACAM CADM1 HMCN2 PTPRF KDR CNTN1

8.56e-042351217SM00408
DomainIg_sub2

OBSCN HEPACAM CADM1 HMCN2 PTPRF KDR CNTN1

8.56e-042351217IPR003598
DomainAC_N

ADCY6 ADCY8

1.14e-0381212IPR032628
DomainAdcy

ADCY6 ADCY8

1.14e-0381212IPR030672
DomainAC_N

ADCY6 ADCY8

1.14e-0381212PF16214
DomainRibosomal_S5_D2-typ_fold

RPS16 FCSK GFM1

1.37e-03341213IPR020568
DomainDNA/RNA_helicase_DEAH_CS

CHD8 DHX35 DHX29

1.49e-03351213IPR002464
Domain-

RASIP1 STARD9 MDC1

1.62e-033612132.60.200.20
DomainFHA_dom

RASIP1 STARD9 MDC1

1.62e-03361213IPR000253
DomainCAP_GLY

DCTN1 TBCE

1.81e-03101212PF01302
DomainCAP_GLY

DCTN1 TBCE

1.81e-03101212SM01052
Domain-

DCTN1 TBCE

1.81e-031012122.30.30.190
DomainCAP_GLY_1

DCTN1 TBCE

1.81e-03101212PS00845
DomainCAP_GLY_2

DCTN1 TBCE

1.81e-03101212PS50245
DomainCAP-Gly_domain

DCTN1 TBCE

1.81e-03101212IPR000938
DomainDEAH_ATP_HELICASE

CHD8 DHX35 DHX29

1.90e-03381213PS00690
DomainBand_7

PHB2 PHB1

2.20e-03111212IPR001107
DomainBand_7

PHB2 PHB1

2.20e-03111212PF01145
DomainPHB

PHB2 PHB1

2.20e-03111212SM00244
DomainRossmann-like_a/b/a_fold

CTU2 ASS1 CTU1

2.71e-03431213IPR014729
Domain-

CTU2 ASS1 CTU1

2.71e-034312133.40.50.620
DomainTRYPSIN_SER

PRTN3 PRSS41 PRSS12 PRSS56

2.79e-03901214IPR033116
DomainG_TR_1

HBS1L GFM1

3.10e-03131212PS00301
DomainEXOIII

ERI2 REXO1

3.60e-03141212SM00479
DomainExonuclease_RNaseT/DNA_pol3

ERI2 REXO1

3.60e-03141212IPR013520
DomainRNase_T

ERI2 REXO1

3.60e-03141212PF00929
DomainTRYPSIN_HIS

PRTN3 PRSS41 PRSS12 PRSS56

4.53e-031031214IPR018114
DomainSMAD_FHA_domain

RASIP1 STARD9 MDC1

4.65e-03521213IPR008984
DomainTRYPSIN_SER

PRTN3 PRSS41 PRSS12 PRSS56

5.01e-031061214PS00135
DomainTRYPSIN_HIS

PRTN3 PRSS41 PRSS12 PRSS56

5.18e-031071214PS00134
DomainA/G_cyclase_CS

ADCY6 ADCY8

5.31e-03171212IPR018297
DomainDUF1605

DHX35 DHX29

5.31e-03171212IPR011709
DomainOB_NTP_bind

DHX35 DHX29

5.31e-03171212PF07717
DomainIntegrin_alpha-2

ITGA11 ITGA2B

5.95e-03181212IPR013649
DomainEFTu-like_2

HBS1L GFM1

5.95e-03181212IPR004161
DomainZF_ZZ_2

MIB2 MIB1

5.95e-03181212PS50135
DomainZF_ZZ_1

MIB2 MIB1

5.95e-03181212PS01357
DomainINTEGRIN_ALPHA

ITGA11 ITGA2B

5.95e-03181212PS00242
Domain-

ADCY6 ADCY8

5.95e-031812123.30.70.1230
DomainIntegrin_alpha2

ITGA11 ITGA2B

5.95e-03181212PF08441
DomainIntegrin_alpha

ITGA11 ITGA2B

5.95e-03181212IPR000413
DomainZZ

MIB2 MIB1

5.95e-03181212PF00569
DomainHA2

DHX35 DHX29

5.95e-03181212SM00847
DomainHA2

DHX35 DHX29

5.95e-03181212PF04408
DomainNucleotide_cyclase

ADCY6 ADCY8

5.95e-03181212IPR029787
DomainHelicase-assoc_dom

DHX35 DHX29

5.95e-03181212IPR007502
DomainGTP_EFTU_D2

HBS1L GFM1

5.95e-03181212PF03144
DomainG_TR_2

HBS1L GFM1

5.95e-03181212PS51722
Domain-

EED GEMIN5 PLXND1 ERCC8 TECPR2 NBEAL2 FBXW7

6.01e-0333312172.130.10.10
DomainIG

OBSCN HEPACAM CADM1 HMCN2 PTPRF CD33 KDR CNTN1

6.14e-034211218SM00409
DomainIg_sub

OBSCN HEPACAM CADM1 HMCN2 PTPRF CD33 KDR CNTN1

6.14e-034211218IPR003599
DomainWD40/YVTN_repeat-like_dom

EED GEMIN5 PLXND1 ERCC8 TECPR2 NBEAL2 FBXW7

6.20e-033351217IPR015943
DomainPeptidase_S1A

PRTN3 PRSS41 PRSS12 PRSS56

6.27e-031131214IPR001314
PathwayPID_NOTCH_PATHWAY

SSPOP NCOR1 MIB1 CNTN1 FBXW7

4.02e-0559925M17
PathwayKEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY

ADCY6 ADCY8 ADRB2

1.16e-0415923M47794
PathwayREACTOME_SIGNALING_BY_NOTCH1

MIB2 NCOR1 MIB1 CNTN1 FBXW7

1.20e-0474925M616
PathwayREACTOME_PROCESSING_OF_SMDT1

PHB2 PHB1 YME1L1

1.42e-0416923M27819
PathwayWP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE

ADCY6 ADCY8 ADRB2

1.42e-0416923M39849
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

ITGA11 COL9A2 DSPP COL22A1 ITGA2B TRAPPC4 KDR LOXL3 PLEC

1.47e-04300929M610
PathwayREACTOME_MITOCHONDRIAL_CALCIUM_ION_TRANSPORT

PHB2 PHB1 YME1L1

1.71e-0417923MM15541
PathwayWP_ENVELOPE_PROTEINS_AND_THEIR_POTENTIAL_ROLES_IN_EDMD_PHYSIOPATHOLOGY

LEMD3 ADCY6 ADCY8 PLEC

2.25e-0446924M39828
PathwayREACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

MIB2 MIB1 CNTN1

3.79e-0422923M27210
PathwayREACTOME_MITOCHONDRIAL_CALCIUM_ION_TRANSPORT

PHB2 PHB1 YME1L1

4.33e-0423923M27816
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

FLNA HBS1L PHB2 GEMIN5 RPS16 CHD8 DCTN1 HNRNPH3 EHD4 PHB1 PLCD3 METTL13 SLC25A1 MDC1 ASS1 MIB1 PLEKHA5 SCRIB PLEC DHX29 YME1L1 ATP5F1A FTSJ3

5.24e-1013531252329467282
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FLNA DUSP5 OBSCN GEMIN5 CHD8 MIB2 PLXND1 DCTN1 REXO1 MAP3K5 PLCD3 PIKFYVE NCOR1 PTPRF NBEAL2 TLN2 DENND5A PLEC TBCD

1.66e-0811051251935748872
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

FLNA PHB2 RPS16 DCTN1 SPECC1 PLCD3 METTL13 SLC25A1 MDC1 ASS1 PPP1R9B DHX35 SCRIB PLEC ATP5F1A FTSJ3

3.23e-079491251636574265
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

FLNA ATG2B GEMIN5 CHD8 NUDCD2 DCTN1 LIN9 NCOR1 PLEKHA5 CRYBG3 PLEC

3.61e-074181251134709266
Pubmed

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.

FLNA PHB2 RPS16 DCTN1 PHB1 NCOR1 SLC25A1 SCRIB YME1L1 ATP5F1A

5.10e-073441251036282215
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

ANKRD35 EED GEMIN5 MIB2 GXYLT2 HMCN2 SLC35D3 MDC1 PLEKHA5 TLN2

7.90e-073611251026167880
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

LEMD3 DUSP5 EHD4 NCOR1 CADM1 PTPRF MIB1 ROCK1 PPP1R9B SCRIB CRYBG3 YME1L1 ATP2B4 ATP5F1A FBXW7 FTSJ3

1.20e-0610491251627880917
Pubmed

Functional proteomics mapping of a human signaling pathway.

FLNA MRI1 LEMD3 DCTN1 PLCD3 NCOR1 CADM1 PTPRF ROCK1 PPP1R9B PLEC TBCD

1.60e-065911251215231748
Pubmed

Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability.

FLNA PHB2 PHB1 ADRB2 GFM1 ATP2B4 ATP5F1A

1.93e-06160125723798571
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

FLNA PHB2 GEMIN5 RPS16 DCTN1 EHD4 PHB1 AP3B2 ROCK1 TLN2 PLEC DHX29 ATP2B4 ATP5F1A

2.34e-068471251435235311
Pubmed

The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs.

FLNA PHB2 RPS16 DCTN1 PHB1 CADM1 SLC25A1 NBEAL2 ATP5F1A

2.54e-06320125928685749
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

FLNA HBS1L PRSS56 PHB2 ZNF622 LYSMD2 GEMIN5 RPS16 DCTN1 HNRNPH3 PHB1 SARS1 SLC25A1 MDC1 ASS1 PLEC ATP5F1A FTSJ3

3.24e-0614151251828515276
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

FLNA GEMIN5 CHD8 EHD4 NCOR1 SARS1 MDC1 ASS1 PLEC

3.42e-06332125932786267
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

FLNA HBS1L PHB2 GEMIN5 RPS16 DCTN1 HNRNPH3 EHD4 PHB1 METTL13 SARS1 STARD9 MDC1 TLN2 GFM1 DHX29 ATP5F1A FTSJ3

3.57e-0614251251830948266
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

FLNA PHB2 GEMIN5 RPS16 SORBS1 DCTN1 SPECC1 SARS1 AP3B2 PLEKHA5 TLN2 PPP1R9B SCRIB PLEC DHX29 ATP2B4 ATP5F1A CNTN1

3.78e-0614311251837142655
Pubmed

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms.

PHB2 RPS16 HNRNPH3 PHB1 PTPRF SLC25A1 ATP2B4 ATP5F1A

4.33e-06256125824189400
Pubmed

Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies.

PHB2 PHB1 SLC25A1 YME1L1 ATP5F1A

4.47e-0667125530669930
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

FLNA HBS1L ATG2B GEMIN5 CHD8 DCTN1 NCOR1 SLC25A1 MDC1 PLEKHA5 SCRIB

5.03e-065491251138280479
Pubmed

STUB1 is targeted by the SUMO-interacting motif of EBNA1 to maintain Epstein-Barr Virus latency.

FLNA SPECC1 HNRNPH3 PHB1 SLC25A1 TBCE FTSJ3

6.45e-06192125732176739
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

LEMD3 ATG2B PHB2 ZNF622 NUDCD2 HNRNPH3 EHD4 PHB1 PIKFYVE SARS1 ASS1 MIB1 DHX35 CRYBG3 GFM1 YME1L1 ATP5F1A FTSJ3

6.96e-0614961251832877691
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

MRI1 PHB2 ZNF622 RPS16 DCTN1 EHD4 METTL13 SLC25A1 SCRIB DHX29 YME1L1 ATP5F1A

9.46e-067041251229955894
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

HBS1L ATG2B PHB2 THSD1 PHB1 PLEKHA5 ROCK1 SCRIB CRYBG3 DHX29 ATP5F1A TBCE

1.00e-057081251239231216
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

PHB2 CHD8 SORBS1 DCTN1 MAP3K5 NCOR1 DCHS1 PLEKHA5 ROCK1 TLN2 PPP1R9B SCRIB ATP2B4 CNTN1

1.01e-059631251428671696
Pubmed

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation.

PHB2 RPS16 HNRNPH3 PHB1 CADM1 SLC25A1 SCRIB PLEC DHX29 ATP5F1A CNTN1

1.23e-056041251137616343
Pubmed

Targeted disruption of Mib2 causes exencephaly with a variable penetrance.

MIB2 MIB1

1.28e-052125217987667
Pubmed

Prohibitin binds to C3 and enhances complement activation.

PHB2 PHB1

1.28e-052125217070910
Pubmed

Effect of Adenylyl Cyclase Type 6 on Localized Production of cAMP by β-2 Adrenoceptors in Human Airway Smooth-Muscle Cells.

ADCY6 ADRB2

1.28e-052125231068382
Pubmed

Identification of prohibitin as a Chikungunya virus receptor protein.

PHB2 PHB1

1.28e-052125222997079
Pubmed

Expression and localization of tubulin cofactors TBCD and TBCE in human gametes.

TBCD TBCE

1.28e-052125228583220
Pubmed

Sirt3 mitigates LPS-induced mitochondrial damage in renal tubular epithelial cells by deacetylating YME1L1.

SIRT3 YME1L1

1.28e-052125236433732
Pubmed

Prohibitins are required for cancer cell proliferation and adhesion.

PHB2 PHB1

1.28e-052125220856874
Pubmed

Mitochondrial dysfunction and adipogenic reduction by prohibitin silencing in 3T3-L1 cells.

PHB2 PHB1

1.28e-052125222479600
Pubmed

The PHB1/2 phosphocomplex is required for mitochondrial homeostasis and survival of human T cells.

PHB2 PHB1

1.28e-052125218086671
Pubmed

Extracellular SOD-derived H2O2 promotes VEGF signaling in caveolae/lipid rafts and post-ischemic angiogenesis in mice.

KDR SOD3

1.28e-052125220422004
Pubmed

Biallelic TBCD Mutations Cause Early-Onset Neurodegenerative Encephalopathy.

TBCD TBCE

1.28e-052125227666374
Pubmed

Inhibition of PIKfyve prevents myocardial apoptosis and hypertrophy through activation of SIRT3 in obese mice.

SIRT3 PIKFYVE

1.28e-052125228396567
Pubmed

Identification of the cellular prohibitin 1/prohibitin 2 heterodimer as an interaction partner of the C-terminal cytoplasmic domain of the HIV-1 glycoprotein.

PHB2 PHB1

1.28e-052125219906925
Pubmed

Expression of prohibitins on the surface of activated T cells.

PHB2 PHB1

1.28e-052125222417827
Pubmed

Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence.

PHB2 PHB1

1.28e-052125211302691
Pubmed

SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.

MRI1 PRTN3 PHB2 GEMIN5 DCTN1 HNRNPH3 PHB1 SLC25A1 GFM1 TBCD TBCE

1.29e-056071251139147351
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

FLNA GEMIN5 CHD8 NCOR1 PLEKHA5 TLN2 SCRIB DHX29 CTU1 FTSJ3

1.47e-055031251016964243
Pubmed

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.

PHB2 RPS16 DCTN1 PHB1 PPP1R9B PLEC ATP2B4 ATP5F1A CNTN1

1.61e-05403125930562941
Pubmed

Defining the membrane proteome of NK cells.

FLNA HBS1L GEMIN5 RPS16 DCTN1 EHD4 PHB1 NCOR1 NBEAL2 PLEKHA5 YME1L1 TAP2 ATP2B4 ATP5F1A ALG1

2.05e-0511681251519946888
Pubmed

Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease.

FLNA PHB2 RPS16 SORBS1 PHB1 TLN2 PLEC ATP5F1A TBCD

2.15e-05418125932552912
Pubmed

Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.

PHB2 CHD8 NUDCD2 PHB1 NCOR1 MDC1

2.23e-05156125637108203
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

MRI1 CCDC80 DCTN1 PHB1 SCRIB PLEC YME1L1 TAP2 ATP2B4 ATP5F1A ALG1

2.32e-056471251126618866
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

FLNA MRI1 PHB2 GEMIN5 CHD8 PHB1 SLC25A1 SCRIB GFM1 TBCE

2.45e-055341251035032548
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

RSAD1 OXLD1 PHB2 SIRT3 PHB1 SARS1 DNLZ SLC25A1 SARDH GFM1 DHX29 YME1L1 CTU1 ATP5F1A

2.54e-0510471251418614015
Pubmed

Tagging genes with cassette-exchange sites.

LEMD3 ZNF622 GEMIN5 CHD8 REXO1 NCOR1 PLEC DHX29

3.02e-05335125815741177
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

RSAD1 OXLD1 PHB2 SIRT3 PHB1 SARS1 SLC25A1 SARDH GFM1 DHX29 YME1L1 CTU1 ATP5F1A

3.06e-059261251320877624
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

HBS1L LEMD3 GEMIN5 CHD8 MDC1 DHX35 SCRIB DHX29 FTSJ3

3.21e-05440125934244565
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

FLNA EED PHB2 RPS16 NUDCD2 DCTN1 HNRNPH3 EHD4 PHB1 PLEC ATP5F1A FTSJ3

3.44e-058031251236517590
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

DSPP SORBS1 ADRB2 PCDH15 CNGB1 TBCE

3.74e-05171125620201926
Pubmed

Proteomic investigation of the interactome of FMNL1 in hematopoietic cells unveils a role in calcium-dependent membrane plasticity.

PHB2 GEMIN5 PLEC TAP2

3.77e-0552125423182705
Pubmed

Rasip1 is required for endothelial cell motility, angiogenesis and vessel formation.

RASIP1 KDR

3.84e-053125219272373
Pubmed

PMCA4 gene expression is regulated by the androgen receptor in the mouse testis during spermatogenesis.

PLEKHA5 ATP2B4

3.84e-053125233355366
Pubmed

Gain-of-Function Mutation in Filamin A Potentiates Platelet Integrin αIIbβ3 Activation.

FLNA ITGA2B

3.84e-053125228428218
Pubmed

FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling.

FLNA ROCK1

3.84e-053125216862148
Pubmed

Mind bomb-2 is an E3 ligase for Notch ligand.

MIB2 MIB1

3.84e-053125215824097
Pubmed

Identification of prohibitin and prohibiton as novel factors binding to the p53 induced gene 3 (PIG3) promoter (TGYCC)(15) motif.

PHB2 PHB1

3.84e-053125224388982
Pubmed

Prohibitin-2 binding modulates insulin-like growth factor-binding protein-6 (IGFBP-6)-induced rhabdomyosarcoma cell migration.

PHB2 PHB1

3.84e-053125224003225
Pubmed

Stomatin-like protein 2 binds cardiolipin and regulates mitochondrial biogenesis and function.

PHB2 PHB1

3.84e-053125221746876
Pubmed

Narciclasine inhibits angiogenic processes by activation of Rho kinase and by downregulation of the VEGF receptor 2.

ROCK1 KDR

3.84e-053125231381906
Pubmed

Prohibitins are involved in protease-activated receptor 1-mediated platelet aggregation.

PHB2 PHB1

3.84e-053125222212092
Pubmed

Prohibitins and the cytoplasmic domain of CD86 cooperate to mediate CD86 signaling in B lymphocytes.

PHB2 PHB1

3.84e-053125223241883
Pubmed

Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural Precursor Cells by Signaling Through LAR and RPTPσ and Modulation of the Rho/ROCK Pathway.

PTPRF ROCK1

3.84e-053125225703008
Pubmed

Structural mechanism of integrin inactivation by filamin.

FLNA ITGA2B

3.84e-053125225849143
Pubmed

Angiogenesis is uncoupled from osteogenesis during calvarial bone regeneration.

KDR FBXW7

3.84e-053125238834586
Pubmed

Disrupted filamin A/αIIbβ3 interaction induces macrothrombocytopenia by increasing RhoA activity.

FLNA ITGA2B

3.84e-053125230602618
Pubmed

PDE8 Is Expressed in Human Airway Smooth Muscle and Selectively Regulates cAMP Signaling by β2-Adrenergic Receptors and Adenylyl Cyclase 6.

ADCY6 ADRB2

3.84e-053125229262264
Pubmed

SLP-2 interacts with prohibitins in the mitochondrial inner membrane and contributes to their stability.

PHB2 PHB1

3.84e-053125218339324
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

MRI1 LEMD3 PHB2 RPS16 SPECC1 ADCY6 EHD4 PHB1 PIKFYVE SLC25A1 GFM1 ATP2B4 ATP5F1A

4.06e-059521251338569033
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

LEMD3 SPECC1 ADCY6 CADM1 PTPRF NBEAL2 PLEKHA5 ROCK1 SCRIB ATP2B4

4.19e-055691251030639242
Pubmed

Hrd1-mediated ACLY ubiquitination alleviate NAFLD in db/db mice.

FLNA PLEC ATP5F1A

4.21e-0519125332888949
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

ANKRD35 FLNA ZNF622 RPS16 NUDCD2 DCTN1 SPECC1 HNRNPH3 NCOR1 SARS1 SLC25A1 ASS1 DHX35 ATP5F1A FTSJ3

4.34e-0512471251527684187
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

FLNA PHB2 RPS16 CHD8 SPECC1 NCOR1 MDC1 ATP5F1A

4.73e-05357125837059091
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

FLNA PHB2 RPS16 SPECC1 HNRNPH3 PHB1 SLC25A1 MDC1 ASS1 PLEKHA5 PPP1R9B SCRIB PLEC ATP5F1A FTSJ3

4.75e-0512571251536526897
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

MRI1 PHB2 RPS16 DCTN1 HNRNPH3 PHB1 NCOR1 METTL13 SLC25A1 SCRIB GFM1 YME1L1 ATP5F1A ALG1 TBCD

4.75e-0512571251537317656
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

LEMD3 PHB2 GEMIN5 SPECC1 PHB1 SLC25A1 PPP1R9B PLEC YME1L1 ATP5F1A FTSJ3

4.79e-057011251130196744
Pubmed

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.

FLNA PHB2 RPS16 PHB1 PLCD3 SLC25A1 ASS1 SCRIB PLEC ATP5F1A

4.91e-055801251035676659
Pubmed

Prohibitin regulates TGF-beta induced apoptosis as a downstream effector of Smad-dependent and -independent signaling.

COL9A2 PHB1 PLEC

5.75e-0521125319725029
Pubmed

Combined treatment of human multiple myeloma cells with bortezomib and doxorubicin alters the interactome of 20S proteasomes.

PHB2 HNRNPH3 PHB1 ATP5F1A

5.81e-0558125430009671
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

FLNA PHB2 RPS16 HNRNPH3 PHB1 SLC25A1 SCRIB GFM1 ATP5F1A

6.68e-05484125931995728
Pubmed

Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.

FLNA PHB2 RPS16 SPECC1 PHB1 SLC25A1 DHX35 PLEC ATP5F1A

7.11e-05488125931324722
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

LEMD3 PHB2 DCTN1 SPECC1 LIN9 PHB1 ERCC8 ASS1 MIB1 TLN2 DHX35 SCRIB TBCD FAM110B

7.31e-0511551251420360068
Pubmed

Ascorbic acid is a regulator of the intracellular cAMP concentration: old molecule, new functions?

ADCY6 ADCY8

7.65e-054125218835269
Pubmed

BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor.

MIB1 FBXW7

7.65e-054125230044990
Pubmed

Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities.

ROCK1 KDR

7.65e-054125215247219
Pubmed

Positive regulation of ASK1-mediated c-Jun NH(2)-terminal kinase signaling pathway by the WD-repeat protein Gemin5.

GEMIN5 MAP3K5

7.65e-054125217541429
Pubmed

Analysis of the Rab GTPase Interactome in Dendritic Cells Reveals Anti-microbial Functions of the Rab32 Complex in Bacterial Containment.

PHB2 PHB1

7.65e-054125226885862
Pubmed

Identification of a molecular component of the mitochondrial acetyltransferase programme: a novel role for GCN5L1.

SIRT3 ATP5F1A

7.65e-054125222309213
Pubmed

Impaired vascular remodeling in the yolk sac of embryos deficient in ROCK-I and ROCK-II.

ROCK1 KDR

7.65e-054125221895889
Pubmed

Chaperonin-mediated folding of actin and tubulin.

TBCD TBCE

7.65e-05412528567715
Pubmed

Tubulin subunits exist in an activated conformational state generated and maintained by protein cofactors.

TBCD TBCE

7.65e-05412529265649
Pubmed

The IgM antigen receptor of B lymphocytes is associated with prohibitin and a prohibitin-related protein.

PHB2 PHB1

7.65e-05412528070406
Pubmed

Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation.

ITGA2B KDR

7.65e-054125216690964
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

FLNA HBS1L PHB2 GEMIN5 RPS16 CHD8 HNRNPH3 PHB1 NCOR1 METTL13 SLC25A1 MIB1 PLEC ATP5F1A FTSJ3

8.08e-0513181251530463901
Pubmed

Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA-splicing factors during adipogenesis.

FLNA PHB2 RPS16 PLEC ATP5F1A

8.20e-05122125529530978
Pubmed

A Noncanonical Role of Fructose-1, 6-Bisphosphatase 1 Is Essential for Inhibition of Notch1 in Breast Cancer.

FLNA PHB2 RPS16 PLCD3 SLC25A1 ATP5F1A FBXW7

8.24e-05286125732041737
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

FLNA HBS1L RPS16 SLC25A1 AP3B2 TLN2 SCRIB DHX29 TBCD

8.30e-05498125936634849
InteractionPCDHGB1 interactions

LEMD3 PCDHGA11 SPECC1 PTPRF DCHS1 ATP2B4 CNTN1

4.74e-07771247int:PCDHGB1
InteractionTOP3B interactions

FLNA DUSP5 OBSCN GEMIN5 RPS16 CHD8 MIB2 PLXND1 DCTN1 REXO1 MAP3K5 PHB1 PLCD3 PIKFYVE NCOR1 PTPRF NBEAL2 MDC1 MIB1 TLN2 PPP1R9B DENND5A PLEC TBCD

9.18e-06147012424int:TOP3B
Cytoband8q24.3

IQANK1 COL22A1 SCRIB OPLAH

2.68e-0411312548q24.3
CytobandEnsembl 112 genes in cytogenetic band chr8q24

IQANK1 COL22A1 ADCY8 SCRIB PLEC OPLAH

4.44e-043551256chr8q24
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

OBSCN HMCN2 PTPRF KDR CNTN1

6.97e-04161795593
GeneFamilyAdenylate cyclases|Deafness associated genes

ADCY6 ADCY8

8.29e-041079253
GeneFamilyActins|Deafness associated genes

DSPP TSPEAR LOXHD1 PCDH15

1.52e-031137941152
GeneFamilyImmunoglobulin like domain containing

HEPACAM CADM1 HMCN2 KDR CNTN1

1.57e-03193795594
GeneFamilyExonucleases

ERI2 REXO1

2.17e-0316792544
GeneFamilyDEAH-box helicases

DHX35 DHX29

2.17e-0316792500
GeneFamilyCadherin related

PCDH15 DCHS1

2.46e-031779224
GeneFamilyProteases, serine

PRSS41 PRSS12 PRSS56

2.64e-0363793738
GeneFamilyCD molecules|Integrin alpha subunits

ITGA11 ITGA2B

2.76e-03187921160
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

MIB2 MIB1

2.76e-031879291
GeneFamilyAdenosine receptors|V-set domain containing

HEPACAM CADM1 CD33 KDR

5.66e-03163794590
GeneFamilyWD repeat domain containing

EED GEMIN5 ERCC8 NBEAL2 FBXW7

5.80e-03262795362
CoexpressionDESCARTES_FETAL_LIVER_MEGAKARYOCYTES

FLNA ITGA2B ADCY6 LOXHD1 NBEAL2 SLC35D3 MYEOV

1.26e-051611257M40231
CoexpressionSWEET_LUNG_CANCER_KRAS_DN

LYSMD2 SORBS1 LIN9 ADCY8 RASIP1 CADM1 ADRB2 KDR CNTN1 SOD3

3.60e-0542212510M7396
CoexpressionGSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN

DUSP5 MAP3K5 EHD4 NBEAL2 MIB1 CRYBG3 ATP2B4

4.75e-051981257M3119
CoexpressionGSE11961_MARGINAL_ZONE_BCELL_VS_PLASMA_CELL_DAY7_DN

RSAD1 EED ERI2 SARS1 PLEC CTU1 FAM110B

4.90e-051991257M9323
CoexpressionGSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_DN

ITGA2B EHD4 SCARF1 LOXHD1 SLC25A1 PPP1R9B PLEC

4.90e-051991257M9701
CoexpressionGSE17721_PAM3CSK4_VS_CPG_6H_BMDC_UP

PHB2 RPS16 NUDCD2 SARS1 DNLZ PLEC TBCE

5.06e-052001257M3863
CoexpressionSWEET_LUNG_CANCER_KRAS_DN

LYSMD2 SORBS1 LIN9 ADCY8 RASIP1 CADM1 ADRB2 KDR CNTN1 SOD3

5.51e-0544412510MM1051
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PRTN3 DUSP5 PLXND1 THSD1 EHD4 RASIP1 DCHS1 KDR

4.25e-0817912588f9e538c822940785130297712b75131812a4603
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THSD1 EHD4 RASIP1 GXYLT2 ASS1 PCDH15 KDR

5.54e-0717112573112d15f2a28cf4a71992db4971d960716dc1264
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RPS16 PLXND1 EHD4 RASIP1 STARD9 KDR TBCD

7.82e-07180125716728b9a1c52097e3a460534be71a476ecc54f0f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN COL22A1 SSPOP LOXHD1 PCDH15 TLN2 CNTN1

9.06e-0718412572cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN COL22A1 SSPOP LOXHD1 PCDH15 TLN2 CNTN1

9.06e-071841257ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN COL22A1 SSPOP LOXHD1 PCDH15 TLN2 CNTN1

9.06e-0718412572b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellEndothelial-E|World / shred on cell class and cell subclass (v4)

CCDC80 PLXND1 EHD4 RASIP1 GXYLT2 ASS1 ATP2B4

9.06e-071841257b4c561924c508536fd2112e91e32176b95fdf63a
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCDC80 PLXND1 ADCY6 PLCD3 DCHS1 TLN2 ATP2B4

9.74e-071861257c116cc9f41971622264434ebe29d18e719b0ae19
ToppCelldroplet-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD1 EHD4 SCARF1 RASIP1 CADM1 ADRB2 KDR

1.01e-0618712573827fa80e558b642f3e0036f5ee1a8b69f437e30
ToppCelldroplet-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD1 EHD4 SCARF1 RASIP1 CADM1 ADRB2 KDR

1.01e-0618712571bf696eb03422ea507d3efe58dda1d442a65225d
ToppCelldroplet-Lung-3m-Endothelial-venous_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD1 EHD4 SCARF1 RASIP1 CADM1 ADRB2 KDR

1.01e-061871257ebe4d1216cc0d4c079b413d5a5460cfd3a4af922
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGA11 CCDC80 GXYLT2 AP3B2 PCDH15 LOXL3 SOD3

1.05e-061881257bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR PLEC

1.08e-061891257feedac2751ed770f80bc56fec31662b5b3826f58
ToppCelldroplet-Lung-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LYSMD2 THSD1 EHD4 SCARF1 RASIP1 CADM1 KDR

1.25e-06193125795c9c63bddfed1a84393ccd3578cfe65bc0c1c05
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC80 PLXND1 SCARF1 RASIP1 DCHS1 KDR ATP2B4

1.34e-061951257f55ab1018a6cde7d517b53e6ce44c3f7bde485c4
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC80 PLXND1 SCARF1 RASIP1 DCHS1 KDR ATP2B4

1.34e-061951257ea1b00805391dca8be0883b635768b296369919a
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC80 PLXND1 SCARF1 RASIP1 DCHS1 KDR ATP2B4

1.34e-06195125785df110f753f58ab017018c54ee454edb4428e29
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 THSD1 EHD4 SCARF1 RASIP1 LOXHD1 KDR

1.38e-0619612579b53e3fdb23dbdfc2e7ce012c6b2ce50700c95d5
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR CRYBG3

1.53e-061991257b15304d3d3f6c254969b54a61bee3d9f368840b2
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 THSD1 EHD4 SCARF1 RASIP1 LOXHD1 KDR

1.53e-0619912570d63da0afa93741c37609d879941de202d9ac86c
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

DCTN1 EHD4 ERCC8 PTPRF DHX29 YME1L1 FTSJ3

1.58e-0620012571fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCellLPS-antiTNF-Unknown-Endothelial-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EED LYSMD2 CHD8 DHX35 DENND5A CTU1

3.06e-061421256b66f9602dba30d1d4fbcc49ceb112eb5bd916ba1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 SCARF1 RASIP1 ADRB2 KDR TBCD

5.08e-06155125659035d792c26d870a8b097939e97fa47859ba68c
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HBS1L THSD1 EHD4 SCARF1 KDR CRYBG3

8.33e-0616912568a6d05b5d60b2b2e43a8ff7521feb79cd6dbd940
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ITGA2B SCARF1 RASIP1 STARD9 SCRIB OPLAH

9.21e-0617212563b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCellE12.5-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

9.21e-061721256ba99688e9f46671deccf824b1e77c6db0742d7df
ToppCellE12.5-Endothelial-proliferative_endothelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

9.21e-0617212562136170f6e1204734cec7dbf7b32e7d5179b92b5
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.16e-051791256d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CUBN ASS1 TLN2 SPSB4 SARDH SOD3

1.23e-051811256bec7076efe94898213a62db72d171d737949977e
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CUBN ASS1 TLN2 SPSB4 SARDH SOD3

1.23e-051811256cf149b30b814cf87c9e923ef502cadf7fe4a3597
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA11 PRSS12 TRIM35 AMDHD1 GXYLT2 AP3B2

1.27e-051821256398ce074a04f6482470b488f1affae4af7d2ec58
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THSD1 EHD4 RASIP1 GXYLT2 ASS1 KDR

1.27e-051821256345d0f9d5ee30434bc2aac17608ccdc9e61c8fa3
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CUBN THSD1 EHD4 PLCD3 RASIP1 KDR

1.31e-051831256ce8be9418b473ea94ec806edc7a2078cc30c1703
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA11 SERGEF HRC PPP1R9B CRYBG3 CTU1

1.35e-051841256a6dee97ee4ef9d89e11d17339e0dadaea1210ce5
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLXND1 CUBN ADCY6 SCARF1 RASIP1 ATP2B4

1.35e-051841256087666ba949b129c53d7ace40f9e543e3875a7de
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 EHD4 SCARF1 RASIP1 LOXHD1 KDR

1.39e-051851256a987dbf6adf533c5f8a0a8a465a6c8e67e0ffcc8
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_bronchial_(8)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DUSP5 LYSMD2 THSD1 SCARF1 RASIP1 KDR

1.44e-0518612560cc7504297fd0c97ea50e4b3ff58fcedc4c1cfaa
ToppCellPCW_05-06-Endothelial-Endothelial_mature-lymphatic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LYSMD2 PLXND1 THSD1 SCARF1 RASIP1 KDR

1.44e-05186125686b218a400f9c64f92b050f00b49f09647b17437
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 EHD4 SCARF1 RASIP1 PCDH15 KDR

1.44e-051861256055cc23c4db9aad2d6c62e62c8e58bfe5047c6b1
ToppCellPCW_05-06-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LYSMD2 PLXND1 THSD1 SCARF1 RASIP1 KDR

1.44e-051861256f51c76b1c3c6c49e0ebc9a913d8413e0b6a04d80
ToppCellE12.5-Endothelial|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.48e-051871256b8ed57b3c39ffbf750cd08a3e03ec11dae43d00e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 EHD4 RASIP1 STARD9 KDR TBCD

1.48e-05187125635c382c0aabd46906113e5db30ea24bb8e658899
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.53e-0518812560026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR THSD1 SSPOP SCARF1 RASIP1 KDR

1.53e-051881256524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPEAR THSD1 SSPOP SCARF1 RASIP1 KDR

1.53e-051881256d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.57e-0518912569e58411e51019ca59e78d3e737d65d2bcbbea2be
ToppCellfacs-Heart-RA-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS1 PLXND1 THSD1 SCARF1 RASIP1 KDR

1.57e-0518912561be5067c1e45af7d09c1fd6955952cb9e031a3a0
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-endo_bronchial_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DUSP5 LYSMD2 THSD1 SCARF1 RASIP1 KDR

1.57e-0518912564bc3826e0515b3cf2e2ef72a7b2cf9c32ade1812
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS1 PLXND1 THSD1 SCARF1 RASIP1 KDR

1.57e-05189125630dc1725d43a60017fb12d706f1f85a33de4947e
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.57e-0518912561d660bceee449aebf12fc9af4c74af246837b27a
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.57e-051891256b5fa3a619e3b554a1a45a551c9b6369075fe5615
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.57e-05189125628b9e96a5206b7fdae9b17daf05c8f5d24b6c5ec
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 ITGA2B THSD1 SCARF1 RASIP1 KDR

1.62e-05190125632400c62cb9de4c2b24af4206c21a0215ab12212
ToppCellPCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LYSMD2 PLXND1 THSD1 SCARF1 RASIP1 KDR

1.62e-0519012569a2244c3973aee7270646bf00db7727edb9decc5
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.62e-051901256d4aefae2d3164db6a9e953c54af0151501e9d1da
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 EHD4 RASIP1 STARD9 KDR TBCD

1.67e-051911256f663131a4810584c5854bd64ee7991a237b7707f
ToppCellPCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DUSP5 LYSMD2 THSD1 SCARF1 RASIP1 KDR

1.67e-051911256edfd5eeff69b5de19c5df3d899e42acd7e015913
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.67e-05191125644c596984c6196f6014e0e405dbe5560841e54ff
ToppCellE16.5-samps-Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.67e-051911256e7521d4d24f016d4e531cd492a7a69604f0c9e6f
ToppCellP07-Endothelial-large_vessel_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PLXND1 SPECC1 EHD4 RASIP1 ASS1 PLEC

1.67e-051911256d162917816dd2e4767c97447c1cddae9397713ab
ToppCellE15.5-Endothelial|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.72e-05192125688cc7f14d031a0613d032eb01c93e88c72d3938f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 EHD4 RASIP1 STARD9 KDR TBCD

1.72e-051921256c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCellE15.5-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.77e-0519312569f4ffce4e1440b009b0b5947ebf52b12a644704d
ToppCelldroplet-Lung-3m-Endothelial-capillary_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LYSMD2 THSD1 EHD4 RASIP1 CADM1 KDR

1.77e-0519312561b6317b740cad2439f08b9e9895426d861e7a161
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNA CCDC80 ADCY8 HRC ATP2B4 SOD3

1.77e-05193125688916d9a7d831eb52848599917c04238f8f9812b
ToppCellPCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating3_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LYSMD2 PLXND1 THSD1 SCARF1 RASIP1 KDR

1.77e-051931256f7e4a390921780587b9bd084e495e646fa1ec74f
ToppCellE15.5-Endothelial-proliferative_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.77e-051931256ed6fc4f731624be702563d7d2f0bf366bec1e042
ToppCellE15.5-Endothelial-capillary_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.77e-0519312563b3ffba483d114e9036a6fc64895fc37fc19d3e5
ToppCelldroplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LYSMD2 THSD1 EHD4 RASIP1 CADM1 KDR

1.77e-051931256f5861cfa4401b476229a7c61cd64abad79a4bbfc
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.77e-051931256807fa1443b3c883cb318c71f4fca3c41d58f4910
ToppCellE15.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.77e-0519312561719a741f8458f658e2965853020f485c22d6106
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.77e-0519312561b69f92c6a7a2516e393d3f3c371407ec791343d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DUSP5 PLXND1 EHD4 RASIP1 DCHS1 TBCD

1.82e-051941256cf9cf115dbbb9997f7c303ae07f42f3d80ff9a21
ToppCell15-Airway-Endothelial|Airway / Age, Tissue, Lineage and Cell class

DUSP5 PLXND1 THSD1 SCARF1 RASIP1 KDR

1.82e-051941256ac0e48b0c09a7f57d30dff321b0c30a4c5e16ad9
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

COL9A2 SPECC1 CD33 CRYBG3 ATP5F1A DSE

1.82e-0519412566af2971d83f5ad6aed16d0ceb8bfc52f3947bc10
ToppCell15-Airway-Endothelial-Endothelial|Airway / Age, Tissue, Lineage and Cell class

DUSP5 PLXND1 THSD1 SCARF1 RASIP1 KDR

1.82e-051941256f3851337a2d17f4acef2cd812a766eb0b503748b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 EHD4 RASIP1 STARD9 KDR TBCD

1.82e-051941256f76808666fb875fc787751cbfd924d9be20a8192
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 THSD1 EHD4 RASIP1 KDR TBCD

1.82e-05194125674a9fdb73f279bebb6337510deab9aaaf9f7e957
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL9A2 SPECC1 CD33 CRYBG3 ATP5F1A DSE

1.82e-0519412565c60670ec24470225fabaa6071fdb4ef6e579840
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 EHD4 RASIP1 STARD9 KDR TBCD

1.82e-051941256b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCellPCW_05-06-Endothelial-Endothelial_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LYSMD2 PLXND1 THSD1 SCARF1 RASIP1 KDR

1.82e-051941256eb279e0d922de921343f0ae032a809f837d915b3
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.82e-05194125623f2a627226aaed468c55adc42ab22e051dfe7fe
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 EHD4 RASIP1 STARD9 KDR TBCD

1.82e-051941256a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA ITGA11 SORBS1 MAP3K5 LOXHD1 CNTN1

1.88e-051951256803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC80 PLXND1 RASIP1 DCHS1 KDR ATP2B4

1.88e-051951256126f46dd15dddcf5701144718bb8ba1ce84b2d1d
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.88e-051951256f65053811074a7f2ff0368f3a63b88e2a08da1a0
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.88e-051951256ccfb80e3bfdf5304fa798e0a47b473955ecc0c6d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA ITGA11 SORBS1 MAP3K5 LOXHD1 CNTN1

1.88e-0519512564f70157d42a16ff0259bc24a62803c4df4285c44
ToppCellfacs-Heart-RA-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS1 PLXND1 THSD1 SCARF1 RASIP1 KDR

1.88e-05195125630c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 EHD4 RASIP1 STARD9 KDR TBCD

1.93e-0519612568ad8efb631164b46f0c082572270188e5ead20bf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 SORBS1 SPECC1 MAP3K5 GXYLT2 CNTN1

1.93e-0519612562b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 EHD4 RASIP1 STARD9 KDR TBCD

1.93e-051961256ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 EHD4 RASIP1 STARD9 KDR TBCD

1.93e-051961256b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 EHD4 RASIP1 STARD9 KDR TBCD

1.93e-0519612569606ea7e42f707e69ea891b3521037613b9675f5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 EHD4 RASIP1 STARD9 KDR TBCD

1.93e-051961256145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 EHD4 RASIP1 STARD9 KDR TBCD

1.93e-051961256d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 EHD4 RASIP1 STARD9 KDR TBCD

1.99e-051971256cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 EHD4 RASIP1 STARD9 KDR TBCD

1.99e-0519712560f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.99e-051971256131bc6ef55f467cc802db68daf7e7d757ea64fc6
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 THSD1 EHD4 SCARF1 RASIP1 KDR

1.99e-0519712564623cce5eca0c26c8103950e9874b40918226aa5
DiseaseMultiple Epiphyseal Dysplasia

FLNA COL9A2 KDR

6.93e-05201193C0026760
DiseaseStickler syndrome, type 1

COL9A2 LOXL3

1.60e-0451192C2020284
Diseaseplatelet measurement

HBS1L ITGA2B ERCC8 PTPRF TECPR2 NBEAL2 PLEC

2.98e-043151197EFO_0005036
DiseaseHydrops Fetalis, Non-Immune

THSD1 ALG1

3.34e-0471192C0455988
Diseasearteriovenous malformations of the brain (implicated_via_orthology)

LEMD3 SARS1

3.34e-0471192DOID:0060688 (implicated_via_orthology)
DiseaseAlzheimer disease, peptic ulcer disease

PHB1 RASIP1 CD33

5.26e-04391193MONDO_0004247, MONDO_0004975
DiseaseColorectal Carcinoma

OBSCN TSPEAR CUBN ERI2 ADCY8 DCHS1 KDR CNTN1 FAM110B FBXW7

5.66e-0470211910C0009402
Diseasemitral valve prolapse (is_implicated_in)

FLNA DCHS1

5.70e-0491192DOID:988 (is_implicated_in)
Diseasegranulocyte count

ANKRD35 HBS1L LIN9 EHD4 ADRB2 SPSB4

5.91e-042541196EFO_0007987
Diseasehearing impairment

DSPP LOXHD1 PCDH15 TRAPPC4

6.78e-04981194C1384666
DiseaseFacies

CHD8 TBCE

7.11e-04101192C0282631
Diseaseneutrophil measurement

HBS1L PRTN3 ADRB2 PLEC GFM1

7.72e-041771195EFO_0803548
Diseasemean platelet volume

PCDHGA11 SORBS1 PLXND1 ITGA2B LIN9 SIRT3 SCARF1 RASIP1 METTL13 PLEC DSE TBCD

8.71e-04102011912EFO_0004584
Diseasegranulins measurement

ITGA2B SARS1

1.04e-03121192EFO_0008141
Diseasebrain aneurysm

CCDC80 SIRT3 SCARF1 MYEOV

1.15e-031131194EFO_0003870
DiseaseMammary Carcinoma, Human

FLNA CTU2 PHB1 NCOR1 CADM1 KDR CTU1 FBXW7

1.33e-035251198C4704874
DiseaseMammary Neoplasms, Human

FLNA CTU2 PHB1 NCOR1 CADM1 KDR CTU1 FBXW7

1.33e-035251198C1257931
DiseaseMammary Neoplasms

FLNA CTU2 PHB1 NCOR1 CADM1 KDR CTU1 FBXW7

1.36e-035271198C1458155
Diseaseneutrophil count

HBS1L RPS16 DPP8 LIN9 MAP3K5 EHD4 ADRB2 SLC25A1 CD33 NBEAL2 SERGEF TLN2 SPSB4 TAP2

1.37e-03138211914EFO_0004833
DiseaseLeft ventricular noncompaction

MIB2 MIB1

1.42e-03141192C1960469
DiseaseBreast Carcinoma

FLNA CTU2 PHB1 NCOR1 CADM1 KDR CTU1 FBXW7

1.55e-035381198C0678222
Diseaseplatelet crit

HBS1L CTU2 ITGA2B CUBN EHD4 SCARF1 CD33 DCHS1 MYEOV PLEC ATP2B4

1.65e-0395211911EFO_0007985
Diseaseneutrophil count, eosinophil count

HBS1L LIN9 EHD4 ADRB2 SPSB4

1.75e-032131195EFO_0004833, EFO_0004842
DiseaseSpondyloepiphyseal Dysplasia

FLNA KDR

1.87e-03161192C0038015
DiseaseDiabetic Angiopathies

ADCY8 ASS1

1.87e-03161192C0011875
DiseaseSpondyloepiphyseal Dysplasia Tarda, X-Linked

FLNA KDR

1.87e-03161192C3541456
DiseaseMicroangiopathy, Diabetic

ADCY8 ASS1

1.87e-03161192C0025945
DiseaseSchwartz-Jampel Syndrome, Type 1

FLNA KDR

1.87e-03161192C4551479
DiseaseSchwartz-Jampel Syndrome

FLNA KDR

1.87e-03161192C0036391
DiseaseMelnick-Needles Syndrome

FLNA KDR

1.87e-03161192C0025237
DiseaseVan Buchem disease

FLNA KDR

2.11e-03171192C0432272
DiseaseFeeding difficulties

FCSK TRAPPC4

2.37e-03181192C0232466
Diseasebipolar I disorder

CUBN STARD9 PLEC ATP2B4

2.59e-031411194EFO_0009963
Diseaseosteochondrodysplasia (is_implicated_in)

FLNA COL9A2

2.64e-03191192DOID:2256 (is_implicated_in)
DiseaseOsteochondrodysplasias

FLNA KDR

2.64e-03191192C0029422
DiseaseDyschondroplasias

FLNA KDR

2.64e-03191192C0013366
DiseaseDiGeorge syndrome (implicated_via_orthology)

PLXND1 SLC25A1

2.64e-03191192DOID:11198 (implicated_via_orthology)
Diseasecitrulline measurement

HMCN2 ASS1

2.92e-03201192EFO_0009777
Diseasepolycystic ovary syndrome (biomarker_via_orthology)

NCOR1 ADRB2

3.22e-03211192DOID:11612 (biomarker_via_orthology)
Diseasenicotine dependence symptom count, depressive symptom measurement

ITGA11 ADRB2 PCDH15

3.50e-03751193EFO_0007006, EFO_0009262
Diseaseplatelet component distribution width

HBS1L EED ITGA2B CUBN LIN9 METTL13 PPP1R9B PLEC TAP2

3.56e-037551199EFO_0007984
Diseasereticulocyte measurement

FLNA HBS1L SPECC1 ADCY8 MAP3K5 EHD4 SCARF1 PIKFYVE CD33 TLN2 ATP2B4

3.59e-03105311911EFO_0010700
DiseaseDisproportionate short stature

FLNA COL9A2 TBCE

3.77e-03771193C0878659

Protein segments in the cluster

PeptideGeneStartEntry
ELRIGISHGSVVAGV

ADCY8

1086

P40145
LQEVGIEFSGREHSG

ERI2

201

A8K979
RVVAVEVLHGGGETA

ERICH3

1336

Q5RHP9
SQVEQDGRTGHGLRR

ADRB2

246

P07550
GELLRGAARHGVSQT

CHD8

1931

Q9HCK8
AARHVVAVVLGDVGR

ALG1

31

Q9BT22
SRVEVIGKGHRGTVA

DCTN1

31

Q14203
GDFHRIGSIRVIGGV

CRYBG3

2511

Q68DQ2
EAGGRAGRIHITRAT

ADCY6

506

O43306
EREDTHGGVGRVGTA

DNM1P46

116

Q6ZS02
ELGDVQGHGRVVTSR

SPECC1

766

Q5M775
ESGVLVHEGDRGRQE

DSPP

56

Q9NZW4
EAVHRGDVGRVAALA

ANKRD35

26

Q8N283
KRHRVVVVAGETGSG

DHX29

586

Q7Z478
HRQVVAVTGDGTNDG

ATP2B4

776

P23634
AREHESRGVTGAVGE

ATG2B

2016

Q96BY7
HGVGRIDIVENRFIG

ASS1

261

P00966
TGRVLSIGDGIARVH

ATP5F1A

71

P25705
SIGDGIARVHGLRNV

ATP5F1A

76

P25705
HQAGEEGGKVRRITS

CCDC80

191

Q76M96
GVGRQELLHRVAGEG

AP3B2

856

Q13367
RFRGVQDIVVGEGTH

PHB1

41

P35232
HVELRRVGAVKAAGG

RASIP1

66

Q5U651
GLFAVGEHTGEVRTA

PCDHGA11

616

Q9Y5H2
ETGGQTREHGLLVRS

HBS1L

381

Q9Y450
LREEEQQQHRSGGRG

LEMD3

46

Q9Y2U8
VGGVQGARAVHVESV

RANGRF

71

Q9HD47
GHDGSGAVDVVLEAR

DCHS1

2441

Q96JQ0
RLAGGSSVHEGRVEL

PRSS12

281

P56730
GGRSQHEGRVEVQIG

LOXL3

421

P58215
RGVHDGLFTGQIDAV

LIN9

231

Q5TKA1
AQVPTGREREQHVGG

MDC1

666

Q14676
DVLSGIGVRAGREHF

MAGEC1

1021

O60732
VEHRVRAGDTLQGIA

LYSMD2

71

Q8IV50
GLQSRHVALSVGGRE

NUDCD2

46

Q8WVJ2
DVRRTGGSTVHVVGA

MSS51

256

Q4VC12
GQVLRITGSHVGDEG

HMCN2

1491

Q8NDA2
QETRAGVVHGAIGGA

CD33

251

P20138
EHGASVQRVGGTGRD

ASB18

206

Q6ZVZ8
RGAHVDARNGRGETA

ASB18

241

Q6ZVZ8
GGVFDRGRTDIFHIE

LOXHD1

336

Q8IVV2
VSGGRTITVAGERFH

PLXND1

1081

Q9Y4D7
AEHEGVSVLHGNRGV

GXYLT2

351

A0PJZ3
RLVAVAGESVEGLGH

PDZD3

376

Q86UT5
EGLGHEETVSRIQGQ

PDZD3

386

Q86UT5
GVAHLGEAFRVGVEQ

MYEOV

161

Q96EZ4
ETVVDGVHGAFIRQR

DSE

596

Q9UL01
IRVHIDIGADGRATG

HNRNPH3

221

P31942
VAIFGGVEGHRDEVL

EED

226

O75530
GRERAGGADAVQTVT

EHD4

11

Q9H223
HIEQRGGTETRTAFG

ITGA11

231

Q9UKX5
GAARAAEIVGGHEAQ

PRTN3

21

P24158
VRESVFTVEGGHRAI

PHB2

36

Q99623
RDVERIHGGGINTLD

ERCC8

36

Q13216
QHGDVVSAIRAGGDE

SLC9A3R1

211

O14745
VVEGGRAVAAAVRGS

OXLD1

6

Q5BKU9
FGDEGAVIEVLHRGS

MIB1

506

Q86YT6
IHALVAGGVESARGR

PRSS41

51

Q7RTY9
VAGGRVAISAEGTRH

OBSCN

461

Q5VST9
GAKVVVESIGARRHG

PCDH15

1281

Q96QU1
EGSIRAVDHAVIGGV

CADM1

366

Q9BY67
VEIREGNATGHLVGR

CUBN

1796

O60494
RAAGRVVGTEALIHA

FCSK

856

Q8N0W3
SLIEGRGHEGAVQEQ

PIKFYVE

891

Q9Y2I7
ARGEQVHRVAGEGAL

DNLZ

131

Q5SXM8
DASRVRVSGQGLHEG

FLNA

2046

P21333
VAGRVAEERGAVLGH

DHX35

116

Q9H5Z1
EEGARRVGATHIVTG

CTU1

156

Q7Z7A3
VLGRHGSNIQVDEVR

DPP8

521

Q6V1X1
VRAHSDGGDGVVSQV

CNTN1

976

Q12860
GRQGVEGRDATDQHI

COL9A2

511

Q14055
EHTARNGEVVGVEPR

FBXW7

51

Q969H0
HRAGIRIFAVGVGEA

COL22A1

166

Q8NFW1
VRVEGDRFKHTNGGT

COL22A1

226

Q8NFW1
GREAVELGHGEVNIT

DENND5A

771

Q6IQ26
GGGIHFTVERTRQAT

AMDHD1

116

Q96NU7
EGGSHVGRRLLEQSA

FAM110B

176

Q8TC76
SDRELQVAGREGGIH

KLHDC9

141

Q8NEP7
RTAGVHIIREQDEAG

HEPACAM

396

Q14CZ8
SVGGDIGVRTVQHQD

METTL13

376

Q8N6R0
AGINRRHGVITGQDG

GFM1

666

Q96RP9
GGVAAVVVLDQGSRH

DUSP5

81

Q16690
TGFSDERHGDVVVVR

CTU2

291

Q2VPK5
ANVTRAHGRIVGGSA

PRSS56

96

P0CW18
GEDRGRHVVDGISRE

PTPRF

651

P10586
GQTGTVHRITDRGDV

MIB2

291

Q96AX9
RRGGAAAVGEGEEHQ

MAP3K5

31

Q99683
GAGGHTREARIQTLE

RSAD1

311

Q9HA92
FRQEVGSHGRDTRGI

SARS1

301

P49591
SGRRVVSHEVVLGGR

REXO1

886

Q8N1G1
RGRVLGISVAIAHGV

SLC35D3

6

Q5M8T2
VRRITGGGGHSAVVT

SERGEF

51

Q9UGK8
GVVRVRQDSGAEGHS

TRIM35

371

Q9UPQ4
FGQRDGIRVGHAVLA

TRAPPC4

51

Q9Y296
EGCEHQGQVHRVGER

SSPOP

1966

A2VEC9
VDERVVLHRGEAGTG

OPLAH

136

O14841
GSEDGTVIIHTVRRG

NBEAL2

2571

Q6ZNJ1
GLLVRAQHEGVVRGT

NCOR1

1121

O75376
EELAGVRGHQGLRDQ

FTSJ3

476

Q8IY81
VDIRVRVKGGGHVAQ

RPS16

66

P62249
RSRDVAQLGDVVHGV

SIRT3

356

Q9NTG7
VGGLQTVRSFGAEEH

TAP2

336

Q03519
AHRGVSAVVVGADRV

MRI1

236

Q9BV20
GIFVSRIAEGGAAHR

SCRIB

891

Q14160
RIAEGGAAHRAGTLQ

SCRIB

896

Q14160
GAAHRAGTLQVGDRV

SCRIB

901

Q14160
EEVFAEHGGQARGHR

HRC

121

P23327
IGDERGGHSAVRKNS

STARD9

4441

Q9P2P6
VTDVNGDGRHDLLVG

ITGA2B

326

P08514
GVGHDEAGEARRLQR

IQANK1

166

A8MXQ7
GGRTVAEHVEAIEGS

SCARF1

666

Q14162
DFGVRRVAGVETQHG

SARDH

246

Q9UL12
VGGGNRRTANVVAHG

CNGB1

1036

Q14028
TADVIGRRVEVNGEH

TBCE

6

Q15813
GRRVEVNGEHATVRF

TBCE

11

Q15813
AQSTDGIRGKVGHAR

SPSB4

81

Q96A44
AVREGHQSEGLRRFG

PLCD3

116

Q8N3E9
RAVVVHAGEDDLGRG

SOD3

176

P08294
GDHQAGLVAGIERTE

THSD1

741

Q9NS62
EQTERHRGGEQAGRK

SORBS1

1191

Q9BX66
VIGELVGHTERVSGF

GEMIN5

56

Q8TEQ6
GIGDCVRQTVRSHGV

SLC25A1

66

P53007
AHGRELLNGAREDVG

TECPR2

576

O15040
VIRGTQGAEEVLRAH

PLEC

1231

Q15149
DRVGHNEVIGVCRTG

SYT10

456

Q6XYQ8
VIGRGAFGEVQLVRH

ROCK1

81

Q13464
GGRVAEELIFGTDHI

YME1L1

656

Q96TA2
GEVVHATRGQSGELA

TLN2

1256

Q9Y4G6
GRLREVHGGGAEREV

TBCD

41

Q9BTW9
VHGGGAEREVALERF

TBCD

46

Q9BTW9
RNVVAVGTGGRGTHD

ZNF622

156

Q969S3
SDGATSGIRIVQVHG

TSPEAR

41

Q8WU66
VGRGERVISFHVTRG

KDR

536

P35968
QKGRGHEEETRGVIS

PLEKHA5

421

Q9HAU0
VTEGGAAHRDGRIQV

PPP1R9B

531

Q96SB3