Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH5 DNAH7 DNAH14

1.75e-0518573GO:0008569
GeneOntologyMolecularFunctionN-acetylglucosamine-6-sulfatase activity

SULF2 SULF1

2.40e-053572GO:0008449
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF3B DNAH5 DNAH7 DNAH14

4.75e-0570574GO:0003777
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH5 DNAH7 DNAH14

6.87e-0528573GO:0051959
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH5 DNAH7 DNAH14

1.60e-0437573GO:0045505
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF3B DNAH5 DNAH7 DNAH14

3.59e-04118574GO:0003774
GeneOntologyMolecularFunctionarylsulfatase activity

SULF2 SULF1

7.13e-0414572GO:0004065
GeneOntologyMolecularFunctionsulfuric ester hydrolase activity

SULF2 SULF1

1.06e-0317572GO:0008484
GeneOntologyMolecularFunctionamino acid binding

GAD2 KARS1 TAT

1.19e-0373573GO:0016597
GeneOntologyMolecularFunctionolfactory receptor activity

OR2T35 OR2AG2 OR2T2 OR5M11 OR52N1 OR2AG1

1.40e-03431576GO:0004984
GeneOntologyMolecularFunctionATP-dependent activity

ABCA3 KIF3B ABCA13 ZNFX1 DNAH5 DNAH7 DNAH14

1.75e-03614577GO:0140657
GeneOntologyMolecularFunctiontRNA binding

KARS1 NAT10 EIF2AK4

1.97e-0387573GO:0000049
GeneOntologyBiologicalProcessesophagus smooth muscle contraction

SULF2 SULF1

7.50e-062572GO:0014846
DomainExtracellular_sulfatase

SULF2 SULF1

8.83e-062562IPR014615
DomainExtracellular_sulfatase_C

SULF2 SULF1

8.83e-062562IPR024609
DomainDUF3740

SULF2 SULF1

8.83e-062562PF12548
DomainDynein_heavy_chain_D4_dom

DNAH5 DNAH7 DNAH14

9.08e-0614563IPR024317
DomainDynein_HC_stalk

DNAH5 DNAH7 DNAH14

9.08e-0614563IPR024743
DomainMT

DNAH5 DNAH7 DNAH14

9.08e-0614563PF12777
DomainAAA_8

DNAH5 DNAH7 DNAH14

9.08e-0614563PF12780
DomainDHC_fam

DNAH5 DNAH7 DNAH14

1.13e-0515563IPR026983
DomainDynein_heavy_dom

DNAH5 DNAH7 DNAH14

1.13e-0515563IPR004273
DomainDynein_heavy

DNAH5 DNAH7 DNAH14

1.13e-0515563PF03028
DomainARM-type_fold

TNPO1 ZNFX1 HEATR1 ARMH3 TRRAP NIPBL

5.17e-04339566IPR016024
DomainABC_A

ABCA3 ABCA13

5.72e-0412562IPR026082
DomainHEAT

TNPO1 HEATR1 NIPBL

7.01e-0458563IPR000357
DomainDynein_heavy_dom-2

DNAH5 DNAH7

7.85e-0414562IPR013602
DomainDHC_N2

DNAH5 DNAH7

7.85e-0414562PF08393
DomainAAA+_ATPase

ABCA3 ABCA13 DNAH5 DNAH7

9.12e-04144564IPR003593
DomainAAA

ABCA3 ABCA13 DNAH5 DNAH7

9.12e-04144564SM00382
DomainSulfatase_CS

SULF2 SULF1

1.03e-0316562IPR024607
DomainOlfact_rcpt

OR2T35 OR2AG2 OR2T2 OR5M11 OR52N1 OR2AG1

1.12e-03393566IPR000725
DomainSULFATASE_1

SULF2 SULF1

1.17e-0317562PS00523
DomainSULFATASE_2

SULF2 SULF1

1.17e-0317562PS00149
DomainHEAT_REPEAT

TNPO1 HEATR1 NIPBL

1.21e-0370563PS50077
DomainSulfatase

SULF2 SULF1

1.31e-0318562PF00884
Domainaa-tRNA-synth_II

KARS1 EIF2AK4

1.31e-0318562IPR006195
DomainSulfatase_N

SULF2 SULF1

1.31e-0318562IPR000917
DomainAA_TRNA_LIGASE_II

KARS1 EIF2AK4

1.31e-0318562PS50862
DomainPID

APBA1 APBA2

3.17e-0328562PF00640
DomainAlkaline_phosphatase_core

SULF2 SULF1

3.88e-0331562IPR017850
DomainAlkaline_Pase-like_a/b/a

SULF2 SULF1

3.88e-0331562IPR017849
Domain-

SULF2 SULF1

3.88e-03315623.40.720.10
DomainSerpin_CS

SERPINI1 SERPINC1

4.13e-0332562IPR023795
DomainPID

APBA1 APBA2

4.13e-0332562PS01179
Domain-

TNPO1 HEATR1 TRRAP NIPBL

4.40e-032225641.25.10.10
DomainEF-hand_8

KCNIP3 RYR2

4.66e-0334562PF13833
Domain-

GAD2 TAT

4.93e-03355623.90.1150.10
DomainSerpin_dom

SERPINI1 SERPINC1

5.21e-0336562IPR023796
DomainPyrdxlP-dep_Trfase_major_sub2

GAD2 TAT

5.21e-0336562IPR015422
DomainSERPIN

SERPINI1 SERPINC1

5.50e-0337562SM00093
DomainSERPIN

SERPINI1 SERPINC1

5.50e-0337562PS00284
DomainSerpin

SERPINI1 SERPINC1

5.79e-0338562PF00079
DomainSerpin_fam

SERPINI1 SERPINC1

6.09e-0339562IPR000215
Domain-

GAD2 TAT

6.09e-03395623.40.640.10
DomainPTB

APBA1 APBA2

6.40e-0340562SM00462
DomainPTB/PI_dom

APBA1 APBA2

6.72e-0341562IPR006020
DomainPyrdxlP-dep_Trfase

GAD2 TAT

6.72e-0341562IPR015424
DomainPyrdxlP-dep_Trfase_major_sub1

GAD2 TAT

6.72e-0341562IPR015421
DomainARM-like

TNPO1 HEATR1 TRRAP NIPBL

8.71e-03270564IPR011989
Pubmed

Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans.

SULF2 SULF1

2.73e-06258212368295
Pubmed

Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity.

SULF2 SULF1

2.73e-06258216901266
Pubmed

Overexpression of Sulf2 in idiopathic pulmonary fibrosis.

SULF2 SULF1

2.73e-06258223418199
Pubmed

Regulation of fractone heparan sulfate composition in young and aged subventricular zone neurogenic niches.

SULF2 SULF1

2.73e-06258234324645
Pubmed

Sulf loss influences N-, 2-O-, and 6-O-sulfation of multiple heparan sulfate proteoglycans and modulates fibroblast growth factor signaling.

SULF2 SULF1

2.73e-06258218687675
Pubmed

The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion.

APBA1 APBA2

2.73e-0625829614075
Pubmed

Loss of endothelial sulfatase-1 after experimental sepsis attenuates subsequent pulmonary inflammatory responses.

SULF2 SULF1

2.73e-06258231461325
Pubmed

HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo.

SULF2 SULF1

2.73e-06258216192265
Pubmed

Functional consequences of the subdomain organization of the sulfs.

SULF2 SULF1

2.73e-06258219520866
Pubmed

Epithelial Deletion of Sulf2 Exacerbates Bleomycin-Induced Lung Injury, Inflammation, and Mortality.

SULF2 SULF1

2.73e-06258228657777
Pubmed

The SULFs, extracellular sulfatases for heparan sulfate, promote the migration of corneal epithelial cells during wound repair.

SULF2 SULF1

2.73e-06258223950901
Pubmed

Expression and localization of X11 family proteins in neurons.

APBA1 APBA2

2.73e-06258227268412
Pubmed

SULF1/SULF2 splice variants differentially regulate pancreatic tumour growth progression.

SULF2 SULF1

2.73e-06258224726914
Pubmed

Endosulfatases SULF1 and SULF2 limit Chlamydia muridarum infection.

SULF2 SULF1

2.73e-06258223480519
Pubmed

Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage.

SULF2 SULF1

2.73e-06258218507859
Pubmed

Differential involvement of the extracellular 6-O-endosulfatases Sulf1 and Sulf2 in brain development and neuronal and behavioural plasticity.

SULF2 SULF1

2.73e-06258220394677
Pubmed

Heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, regulate glomerular integrity by modulating growth factor signaling.

SULF2 SULF1

2.73e-06258226764203
Pubmed

SULFs in human neoplasia: implication as progression and prognosis factors.

SULF2 SULF1

2.73e-06258221599997
Pubmed

SULF1/SULF2 reactivation during liver damage and tumour growth.

SULF2 SULF1

2.73e-06258227013228
Pubmed

A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission.

APBA1 APBA2

2.73e-06258212547917
Pubmed

Gene in the region of the Friedreich ataxia locus encodes a putative transmembrane protein expressed in the nervous system.

APBA1 APBA2

2.73e-0625827678331
Pubmed

The PTB domain: a new protein module implicated in signal transduction.

APBA1 APBA2

2.73e-0625827545337
Pubmed

Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling.

SULF2 SULF1

2.73e-06258227294358
Pubmed

Heparan Sulfate-Editing Extracellular Sulfatases Enhance VEGF Bioavailability for Ischemic Heart Repair.

SULF2 SULF1

2.73e-06258231434553
Pubmed

Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways.

SULF2 SULF1

2.73e-06258220479257
Pubmed

Multi-tasking Sulf1/Sulf2 enzymes do not only facilitate extracellular cell signalling but also participate in cell cycle related nuclear events.

SULF2 SULF1

2.73e-06258229360432
Pubmed

Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions.

SULF2 SULF1

2.73e-06258226448642
Pubmed

Enhanced tumorigenic potential of colorectal cancer cells by extracellular sulfatases.

SULF2 SULF1

2.73e-06258225477293
Pubmed

Diffusion magnetic resonance tractography-based evaluation of commissural fiber abnormalities in a heparan sulfate endosulfatase-deficient mouse brain.

SULF2 SULF1

2.73e-06258235131262
Pubmed

Organ-specific sulfation patterns of heparan sulfate generated by extracellular sulfatases Sulf1 and Sulf2 in mice.

SULF2 SULF1

2.73e-06258222298771
Pubmed

Abnormal Pyramidal Decussation and Bilateral Projection of the Corticospinal Tract Axons in Mice Lacking the Heparan Sulfate Endosulfatases, Sulf1 and Sulf2.

SULF2 SULF1

2.73e-06258232038163
Pubmed

Comparison of primary structure of a neuron-specific protein, X11, between human and mouse.

APBA1 APBA2

2.73e-0625827719031
Pubmed

Expression of Heparan Sulfate Endosulfatases in the Adult Mouse Brain: Co-expression of Sulf1 and Dopamine D1/D2 Receptors.

SULF2 SULF1

2.73e-06258234489650
Pubmed

Sulfs are regulators of growth factor signaling for satellite cell differentiation and muscle regeneration.

SULF2 SULF1

2.73e-06258217920055
Pubmed

X11 and X11-like proteins regulate the level of extrasynaptic glutamate receptors.

APBA1 APBA2

2.73e-06258230411795
Pubmed

WT1-dependent sulfatase expression maintains the normal glomerular filtration barrier.

SULF2 SULF1

8.19e-06358221719793
Pubmed

Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.

KCNIP3 RYR2

8.19e-06358229730765
Pubmed

Facilitation of stress-induced phosphorylation of beta-amyloid precursor protein family members by X11-like/Mint2 protein.

APBA1 APBA2

8.19e-06358214970211
Pubmed

Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2.

SULF2 SULF1

8.19e-06358217116694
Pubmed

Expression of the heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, in the avian and mammalian inner ear suggests a role for sulfation during inner ear development.

SULF2 SULF1

8.19e-06358225370455
Pubmed

Heparan sulfate 6-O-endosulfatases (Sulfs) coordinate the Wnt signaling pathways to regulate myoblast fusion during skeletal muscle regeneration.

SULF2 SULF1

8.19e-06358222865881
Pubmed

Desulfation of Heparan Sulfate by Sulf1 and Sulf2 Is Required for Corticospinal Tract Formation.

SULF2 SULF1

8.19e-06358229062064
Pubmed

Sulf1 and Sulf2 expression in the nervous system and its role in limiting neurite outgrowth in vitro.

SULF2 SULF1

8.19e-06358225448158
Pubmed

RNA interference-mediated silencing of X11alpha and X11beta attenuates amyloid beta-protein levels via differential effects on beta-amyloid precursor protein processing.

APBA1 APBA2

8.19e-06358215699037
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

TNPO1 KARS1 GTF3C1 EIF3L NAT10 HEATR1 TRRAP NIPBL

1.24e-0565358822586326
Pubmed

A rare autism-associated MINT2/APBA2 mutation disrupts neurexin trafficking and synaptic function.

APBA1 APBA2

1.64e-05458230988517
Pubmed

Genetic analysis of Mint/X11 proteins: essential presynaptic functions of a neuronal adaptor protein family.

APBA1 APBA2

1.64e-05458217167098
Pubmed

Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival.

SULF2 SULF1

1.64e-05458217593974
Pubmed

X11 alpha and x11 beta interact with presenilin-1 via their PDZ domains.

APBA1 APBA2

1.64e-05458211083918
Pubmed

Mapping of the human and murine X11-like genes (APBA2 and apba2), the murine Fe65 gene (Apbb1), and the human Fe65-like gene (APBB2): genes encoding phosphotyrosine-binding domain proteins that interact with the Alzheimer's disease amyloid precursor protein.

APBA1 APBA2

1.64e-0545829585438
Pubmed

Distinct expression patterns of Sulf1 and Hs6st1 spatially regulate heparan sulfate sulfation during prostate development.

SULF2 SULF1

1.64e-05458223074159
Pubmed

Deletion of Mint proteins decreases amyloid production in transgenic mouse models of Alzheimer's disease.

APBA1 APBA2

1.64e-05458219118172
Pubmed

X11 proteins regulate the translocation of amyloid beta-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by beta-site-cleaving enzyme in brain.

APBA1 APBA2

1.64e-05458218845544
Pubmed

Novel mediators of amyloid precursor protein signaling.

APBA1 APBA2

1.64e-05458220016085
Pubmed

Mint proteins are required for synaptic activity-dependent amyloid precursor protein (APP) trafficking and amyloid β generation.

APBA1 APBA2

1.64e-05458224742670
Pubmed

HSulf sulfatases catalyze processive and oriented 6-O-desulfation of heparan sulfate that differentially regulates fibroblast growth factor activity.

SULF2 SULF1

1.64e-05458223457216
Pubmed

Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell niche.

SULF2 SULF1

1.64e-05458220855470
Pubmed

Mints as adaptors. Direct binding to neurexins and recruitment of munc18.

APBA1 APBA2

1.64e-05458211036064
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

KARS1 PDPR GTF3C1 EIF3L HEATR1 TRRAP DNAH5 NIPBL

2.13e-0570458829955894
Pubmed

Munc18 interacting proteins: ADP-ribosylation factor-dependent coat proteins that regulate the traffic of beta-Alzheimer's precursor protein.

APBA1 APBA2

2.72e-05558212842896
Pubmed

Junctophilin Proteins Tether a Cav1-RyR2-KCa3.1 Tripartite Complex to Regulate Neuronal Excitability.

RYR2 JPH3

2.72e-05558231461656
Pubmed

Roles of heparan sulfate sulfation in dentinogenesis.

SULF2 SULF1

2.72e-05558222351753
Pubmed

Sulfatase modifying factor 1-mediated fibroblast growth factor signaling primes hematopoietic multilineage development.

SULF2 SULF1

2.72e-05558220643830
Pubmed

Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting.

APBA1 APBA2

2.72e-0555829822620
Pubmed

Munc18-1 regulates early and late stages of exocytosis via syntaxin-independent protein interactions.

APBA1 APBA2

2.72e-05558215563604
Pubmed

Mints, Munc18-interacting proteins in synaptic vesicle exocytosis.

APBA1 APBA2

2.72e-0555829395480
Pubmed

Regulation of APP-dependent transcription complexes by Mint/X11s: differential functions of Mint isoforms.

APBA1 APBA2

4.08e-05658212196555
Pubmed

The cytochrome P450 enzyme CYP24A1 increases proliferation of mutant KRAS-dependent lung adenocarcinoma independent of its catalytic activity.

CYP24A1 CCNB1

4.08e-05658232165494
Pubmed

Interrogation and validation of the interactome of neuronal Munc18-interacting Mint proteins with AlphaFold2.

APBA1 APBA2

4.08e-05658238072052
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

GAD2 DIP2A SULF1 APBA1 APBA2 ZNFX1 HERPUD2 NIPBL JPH3 KLHL4

4.75e-051285581035914814
Pubmed

Sulfatase 1 is an inhibitor of ductal morphogenesis with sexually dimorphic expression in the urogenital sinus.

SULF2 SULF1

5.71e-05758220410206
Pubmed

Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development.

SULF2 SULF1

5.71e-05758218213582
Pubmed

14-3-3 theta binding to cell cycle regulatory factors is enhanced by HIV-1 Vpr.

TNPO1 CCNB1

7.60e-05858218445273
Pubmed

Hippo pathway-dependent and -independent roles of RASSF6.

LATS2 NRDC

7.60e-05858219797269
Pubmed

Genomic analysis of orthologous mouse and human olfactory receptor loci.

OR2AG2 OR2AG1

9.77e-05958211416212
Pubmed

SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation.

SULF2 SULF1

9.77e-05958217720696
Pubmed

Interactions of HIV-1 viral protein R with host cell proteins.

TNPO1 CCNB1

1.22e-041058217586317
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

SULF1 CYP24A1 NAT10 HACE1 PORCN EIF2AK4 HEATR1 NIPBL DNAH14

1.72e-04121558915146197
Pubmed

Dysregulated cell signalling and reduced satellite cell potential in ageing muscle.

SULF2 SULF1

1.78e-041258231647919
Pubmed

The extracellular matrix glycoprotein tenascin-R regulates neurogenesis during development and in the adult dentate gyrus of mice.

GAD2 TNR

1.78e-041258224338367
Pubmed

Sulfatase 2 Modulates Fate Change from Motor Neurons to Oligodendrocyte Precursor Cells through Coordinated Regulation of Shh Signaling with Sulfatase 1.

SULF2 SULF1

1.78e-041258228490013
Pubmed

New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.

RYR2 JPH3

1.78e-041258219095005
Pubmed

Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport.

APBA1 APBA2

1.78e-041258210846156
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

DIP2A CLUAP1 KIF3B NACC2 NAT10 PLET1 ARMH3 TRRAP RETREG3

2.02e-04124258930973865
Pubmed

Expression patterns of sulfatase genes in the developing mouse embryo.

SULF2 SULF1

2.11e-041358220503373
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

DIP2A KARS1 GTF3C1 EIF3L TNR OR52N1 DNAH14

2.18e-0473658729676528
Pubmed

Genetic and physical delineation of the region overlapping the progressive motor neuropathy (pmn) locus on mouse chromosome 13.

HEATR1 RYR2

2.46e-041458211472062
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH5 DNAH7

2.46e-04145829373155
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KARS1 SULF2 PDPR SULF1 NAT10 EIF2AK4

2.49e-0452958614621295
Pubmed

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia.

TNPO1 KARS1 NIPBL

2.52e-047358330224337
Pubmed

The human olfactory receptor gene family.

OR2T35 OR2AG2 OR2T2 OR5M11 OR52N1 OR2AG1

2.81e-0454158614983052
Pubmed

Spatially distinct functions of PAX6 and NKX2.2 during gliogenesis in the ventral spinal cord.

SULF2 SULF1

3.23e-041658219258013
Pubmed

Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes.

GTF3C1 TRRAP

3.66e-041758221653943
Pubmed

Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production.

TNPO1 NRDC NAT10 NIPBL

3.95e-0420658422174317
Pubmed

Polymorphisms in innate immunity genes and risk of childhood leukemia.

SERPINI1 SERPINC1 MUC6 STAT4

3.95e-0420658420438785
Pubmed

Risk of meningioma and common variation in genes related to innate immunity.

SERPINI1 SERPINC1 MUC6 STAT4

4.02e-0420758420406964
Pubmed

Common variation in genes related to innate immunity and risk of adult glioma.

SERPINI1 SERPINC1 MUC6 STAT4

4.10e-0420858419423540
Pubmed

USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier.

GTF3C1 TRRAP

4.11e-041858217846119
Pubmed

HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic intervention.

TNPO1 CCNB1

4.59e-041958221489275
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR2AG2 OR2T2 OR5M11 OR2AG1

4.97e-0421958412213199
CytobandEnsembl 112 genes in cytogenetic band chr16q22

PDPR TAT PMFBP1

1.64e-03183583chr16q22
Cytoband1q43

HEATR1 RYR2

1.92e-03515821q43
Cytoband11p15.4

OR2AG2 OR52N1 OR2AG1

2.11e-0320058311p15.4
Cytoband2q21.1

POTEJ KCNIP3

2.48e-03585822q21.1
CytobandEnsembl 112 genes in cytogenetic band chr1q43

HEATR1 RYR2

2.83e-0362582chr1q43
CytobandEnsembl 112 genes in cytogenetic band chr11p15

OR2AG2 MUC6 OR52N1 OR2AG1

5.66e-03564584chr11p15
Cytoband16q22.1

PDPR TAT

8.62e-0311058216q22.1
Cytoband1q44

OR2T35 OR2T2

8.62e-031105821q44
CytobandEnsembl 112 genes in cytogenetic band chr2q32

DNAH7 STAT4

8.62e-03110582chr2q32
GeneFamilyDyneins, axonemal

DNAH5 DNAH7 DNAH14

7.75e-0617423536
GeneFamilyOlfactory receptors, family 2

OR2T35 OR2AG2 OR2T2 OR2AG1

1.35e-04113424149
GeneFamilyATP binding cassette subfamily A

ABCA3 ABCA13

4.71e-0414422805
GeneFamilySulfatases

SULF2 SULF1

7.87e-0418422410
GeneFamilySerpin peptidase inhibitors

SERPINI1 SERPINC1

3.33e-0337422739
CoexpressionGSE14415_INDUCED_VS_NATURAL_TREG_UP

SERPINI1 LATS2 HERPUD2 KCNIP3 RGS1

1.68e-05149565M2968
CoexpressionGSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_DN

SERPINI1 LATS2 HERPUD2 KCNIP3 RGS1

2.66e-05164565M2972
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA3 PDPR ABCA13 NAT10 OR2AG2

1.21e-061435858f897278f9ccc82ae35e4f30c5f930b2a3eb509d
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Trm_Tgd|Liver / Manually curated celltypes from each tissue

CLUAP1 ABCA3 KIF3B HACE1 RTN4IP1

1.74e-06154585c6308074468235c88ef4ea43ab155d9f86cbf261
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SULF2 ABCA13 CYP24A1 DNAH7 DNAH14

4.62e-06188585af740fa78542438fdff627ea1f74f4eee43316be
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF3B ABCA13 CYP24A1 DNAH5 DNAH7

4.75e-06189585b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCellsevere_influenza-NK|World / disease group, cell group and cell class (v2)

DIP2A GTF3C1 APBA2 STAT4 KLHL4

5.81e-061975858e86a1ee0418e153d4f0bf291006cffc6cf36f71
ToppCellsevere_COVID-19-NK|World / disease group, cell group and cell class (v2)

DIP2A GTF3C1 APBA2 RGS1 STAT4

5.95e-0619858536b1370ef68c4bbe0268933a6ef5e6022d992bdf
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-iNKT-MAIT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

APBA2 RGS1 STAT4 CCNB1

3.34e-05140584a8f3b01d03ee0bf0e752327a98d6b9035930c2b0
ToppCelldroplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNIP3 RGS1 STAT4 KLHL4

5.77e-05161584cd4a736d0cec31477c6e8d3b07a04ede1559854b
ToppCelldroplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNIP3 RGS1 STAT4 KLHL4

5.77e-0516158428930ba576625b98cc15993d1499e9dc5edbb5a9
ToppCelldroplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNIP3 RGS1 STAT4 KLHL4

5.91e-05162584ccba6d8d644fe56060ad388ec3a062b7e3b9f086
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNIP3 RGS1 STAT4 KLHL4

6.19e-05164584e9e5a1462d8ed60b2e5bf603c8c47eb85bce83d5
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SULF2 SULF1 PLET1 TAT

6.49e-05166584545f6c91102568791443717e522f89cb3bd1a070
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNIP3 RGS1 STAT4 KLHL4

6.49e-051665840b7503e27e26dcbf7f1b893c32ce0b21ce58bd4a
ToppCellICU-SEP-Lymphocyte-T_NK-dnT|ICU-SEP / Disease, Lineage and Cell Type

SERPINI1 GTF3C1 RTN4IP1 RGS1

6.49e-0516658496d92316cee20b722fe782db9dafcceb8f2c220b
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-Th1|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CA10 RGS1 RYR2 STAT4

6.64e-051675849c55ec8f70b86d4d3d5c2a6ecd9bff2dafe68c11
ToppCelldroplet-Spleen-nan-21m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SULF2 KCNIP3 RGS1 KLHL4

6.64e-0516758492ddabbe55315856d8ea6f8db1560b6d97636bac
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SULF2 RGS1 STAT4 KLHL4

6.64e-05167584aef22535a76e93472bcedacbb2c6991f3c9c8cd5
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HERPUD2 CA10 RGS1 STAT4

6.80e-051685842765d98f0b7f6861d662937535e051d41dba3500
ToppCelldroplet-Marrow-nan-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SULF2 GTF3C1 NACC2 HACE1

6.96e-051695845f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 ABCA13 DNAH5 DNAH7

6.96e-0516958414aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_HSPB3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CMAHP CA10 DNAH5 DNAH7

7.12e-05170584985c6c9e3c593ed0628a481f06c2c91b2ab5d746
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAT10 HACE1 PLET1 STAT4

7.12e-051705843ad9f950b87ee98f025ab9b4a8ed551e6a9b4764
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC18A2 HACE1 HEATR1 RGS1

7.45e-0517258413d7117f92a92d77d6b4335ed800c585dc8b4511
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC18A2 HACE1 HEATR1 RGS1

7.45e-051725843d83b2f03ad3af4dae3fe6cc0a0ef356872ca94f
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC18A2 HACE1 HEATR1 RGS1

7.45e-05172584a3d431aed12c1192e8dca1dc85b8340fb7354f8d
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC18A2 HACE1 HEATR1 RGS1

7.45e-05172584028a5441242b2cc760cafc1822120180619c63ae
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC18A2 HACE1 HEATR1 RGS1

7.45e-051725849fc70b1a143a8ec910336c23b761d908bb6aecb2
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SULF2 SULF1 PLET1 TAT

8.51e-051785841e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CMAHP CA10 DNAH5 DNAH7

8.51e-051785840e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCell10x3'2.3-week_14-16-Myeloid_DC-DC-tDC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SULF2 SERPINC1 EIF2AK4 RGS1

8.88e-051805843d9f3e6f13e558279b4ef43e2c44c7c50d761745
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 CYP24A1 DNAH5 DNAH7

8.88e-051805841f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HERPUD2 CA10 RGS1 STAT4

9.07e-05181584ee1c5af8ed75dd8a0ed3152ba5b9a42d2a8c2ae4
ToppCell3'-Adult-LargeIntestine-Hematopoietic-T_cells-NK_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

APBA2 TNR RGS1 STAT4

1.01e-04186584e083356f72995645f873ca0157d56bea5e942044
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 CYP24A1 DNAH7 DNAH14

1.01e-04186584f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD2 SERPINI1 APBA1 JPH3

1.03e-04187584e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SULF2 KCNIP3 TNR DNAH5

1.05e-04188584a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

ABCA3 ABCA13 DNAH5 DNAH14

1.05e-04188584ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellCOPD-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

APBA2 CMAHP DNAH5 STAT4

1.05e-04188584186fe1ea328c942910190a4240262c0d8642ea3b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SULF2 KCNIP3 TNR DNAH5

1.05e-04188584c8530c9ff98666c64a94683261af4288cb790a7e
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 SERPINI1 NACC2 SULF1

1.07e-0418958499a13b1b669b0cd36e3096632351d9ade25d1173
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 DNAH5 DNAH7 DNAH14

1.09e-041905843fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellCOVID-19-Heart-T_cell|Heart / Disease (COVID-19 only), tissue and cell type

ABCA13 APBA2 CA10 STAT4

1.09e-04190584e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 DNAH5 DNAH7 DNAH14

1.12e-04191584d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|lymph-node_spleen / Manually curated celltypes from each tissue

APBA2 RGS1 STAT4 KLHL4

1.12e-04191584f802a4686ecf00e8302047bfe23356f24b266cf8
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4/8-lo|lymph-node_spleen / Manually curated celltypes from each tissue

APBA2 RGS1 STAT4 KLHL4

1.14e-041925844d72b9264ed62e0c08cde4078061b348253f6989
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DIP2A GTF3C1 APBA2 STAT4

1.14e-041925841922b0350d3375e67c314dbce8074e5cf986f2ef
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DIP2A GTF3C1 APBA2 STAT4

1.14e-0419258497c197643e59835c6d45dde9e549c9a1b1bb7288
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DIP2A GTF3C1 APBA2 STAT4

1.14e-04192584a4d161e3d48bc020e687808b352325ef9d1cc1f3
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SULF2 APBA1 CA10 KLHL4

1.16e-04193584cd45118ced91b10baed3b1068d4673ec99824b86
ToppCell3'_v3-Lung-Lymphocytic_NK|Lung / Manually curated celltypes from each tissue

DIP2A GTF3C1 APBA2 STAT4

1.16e-04193584a98ee519e0da93ae4a2dcdda1ee8b4138dec131b
ToppCellCTRL-Myeloid-Monocyte_Macrophage|Myeloid / Disease state, Lineage and Cell class

SULF2 CMAHP RGS1 STAT4

1.19e-0419458473459ee062ae1f1a3bb9719dc0b89aae10600e22
ToppCellmoderate-Epithelial-FOXN4+|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CLUAP1 ABCA13 DNAH7 CCNB1

1.19e-041945845dffa578149104dda33774361e9e77b227b5f1ce
ToppCell3'_v3-Lung-Lymphocytic_NK-NK_CD16|Lung / Manually curated celltypes from each tissue

DIP2A GTF3C1 APBA2 STAT4

1.19e-041945843337042eef91a49f621058785723228cf4dfdad4
ToppCellCTRL-Myeloid-Monocyte_Macrophage|CTRL / Disease state, Lineage and Cell class

SULF2 CMAHP RGS1 STAT4

1.19e-04194584927480f56cccd3940b689f3c40ee132fe3e63745
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 ABCA13 DNAH5 DNAH7

1.19e-041945844a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DIP2A GTF3C1 APBA2 STAT4

1.19e-04194584ae5357e2a276473cde1fc8c43acaf9f69da35fd7
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-innate_lymphocytic|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DIP2A GTF3C1 APBA2 STAT4

1.19e-041945843a0b8b5d0354c43da57bb951cd8ba878363c3de5
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 ABCA13 DNAH5 DNAH7

1.21e-04195584d211a836cf711fdb91b10d512f09d462be937cc5
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF3B ABCA13 DNAH5 DNAH7

1.21e-0419558479dc031258579ea328181dda33710dd897f1064a
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLUAP1 ABCA13 DNAH5 DNAH7

1.21e-041955849651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

ABCA13 CMAHP DNAH5 DNAH7

1.23e-04196584af4cdc61830685a888a1209826c23bcf54a43084
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SULF2 KCNIP3 CA10 TNR

1.23e-04196584f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCellhealthy_donor-Myeloid-Dendritic|healthy_donor / Disease condition, Lineage, Cell class and subclass

SULF2 EIF3L EIF2AK4 RGS1

1.23e-04196584ea590b8ea3d13ff93cb5863a44936b0cfdf3b868
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SULF2 KCNIP3 CA10 TNR

1.23e-04196584671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

ABCA13 CMAHP DNAH5 DNAH7

1.23e-041965846d02d494196e3f857d53eea46d9419690d43beca
ToppCellhealthy_donor-Myeloid-Dendritic-cDC|healthy_donor / Disease condition, Lineage, Cell class and subclass

SULF2 EIF3L EIF2AK4 RGS1

1.23e-04196584aac79fc45cab4a16e2fa02652ece0999591261a5
ToppCellnormal_Lung-T/NK_cells-NK|normal_Lung / Location, Cell class and cell subclass

DIP2A GTF3C1 APBA2 STAT4

1.26e-041975846045a05a5f1073d683806eb46a3fa98358414625
ToppCellCaecum-B_cell-B_cell_IgG_Plasma|B_cell / Region, Cell class and subclass

NRDC CA10 MUC6 PMFBP1

1.26e-0419758440c8ff067e8242e2ca083ea04cd6026168191a97
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SULF2 ABCA13 CYP24A1 PMFBP1

1.26e-041975841e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCellInfluenza_Severe-NK|World / Disease group and Cell class

GTF3C1 APBA2 STAT4 KLHL4

1.26e-04197584565d578f7a28a19175d56663bf30c60e0d5e1b22
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SULF2 KCNIP3 CA10 TNR

1.26e-04197584b8dc192fc98428bbb701cc2ea57fc8ad93397785
ToppCellsevere_COVID-19-NK|severe_COVID-19 / disease group, cell group and cell class (v2)

DIP2A GTF3C1 APBA2 STAT4

1.28e-041985847f51e37516f717e424190e6584f1c74d357e2da4
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DIP2A APBA2 RGS1 STAT4

1.28e-0419858458d805e827299292750b09c6283fdbe406b75f79
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_cytokine_secreting_effector_T_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DIP2A APBA2 RGS1 STAT4

1.28e-0419858434c564ece9a2b94dcf646e3c95b5be9c5ecfaafe
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SULF2 KCNIP3 CA10 TNR

1.31e-04199584333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCelldistal-Hematologic-Natural_Killer-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DIP2A GTF3C1 APBA2 STAT4

1.31e-04199584928b152f3bade90dfdb15e46aaa0c85063db0026
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SULF2 KCNIP3 CA10 TNR

1.31e-0419958419a97e27a4758e794ce7246d295e112b47931a48
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SULF2 KCNIP3 CA10 TNR

1.31e-04199584e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SULF2 KCNIP3 CA10 TNR

1.33e-04200584ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-dn_T|ICU-SEP / Disease, condition lineage and cell class

SERPINI1 GTF3C1 RTN4IP1 RGS1

1.33e-042005849ee3e18dc429b9c472e3e366d9bfdbb150daa369
ToppCellLA-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

KCNIP3 RYR2 STAT4

2.06e-04885837232b13a9788f89600411222c0d93bdc3788816f
ToppCellMild/Remission-B_naive-12|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SLC18A2 DNAH5 RETREG3

3.67e-041075831ab09acb66e4282688fd1f6782a4009f4ea18c41
ToppCellMild/Remission-B_naive-12|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SLC18A2 DNAH5 RETREG3

3.77e-041085839c25d199e7d7389c84ff32712eee7e728a4c55cc
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))|Entopeduncular / BrainAtlas - Mouse McCarroll V32

SLC18A2 SERPINC1 ARMH3

4.30e-0411358379ba2eb8f85e5da4c19c838df881c18ffdc450fb
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8|Entopeduncular / BrainAtlas - Mouse McCarroll V32

SLC18A2 SERPINC1 ARMH3

4.30e-0411358391d55fe6fb1c1472867d74461f5b9e4f17db01cd
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Lhx8-Inhibitory_Neuron.Gad1Gad2-Chat_(Nucleus_basalis_(NB))-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

SLC18A2 SERPINC1 ARMH3

4.30e-0411358334ae3dec5ec7585d155ea61de6adc42aa4f45226
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells-iNKT-MAIT|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

APBA2 RGS1 STAT4

7.07e-0413458392981dc68c1b3cdc53f9cf83386c47f0c6c98ae7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 CYP24A1 SERPINC1

7.23e-041355838521107817df49efd9a2e81078c8535ed33e729c
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD2 TNR DNAH5

7.54e-04137583b831d917f5073ccff158662adb281d34f023126a
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD2 TNR DNAH5

7.54e-04137583cf3e928d9a7a7349840bb87475a42a07f65b94f0
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD2 TNR DNAH5

7.54e-041375835d82d6c7eef4ec7a7fae60e37fb956488314987e
ToppCellLPS-IL1RA-Hematopoietic_Mast-Mast_cells-T-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CMAHP RGS1 STAT4

7.70e-0413858310c263c58b83a018791f77098f18927d904cb13b
ToppCellLPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-T-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

APBA2 RGS1 STAT4

7.86e-04139583ecc2a6ecc27748c50885cd4f0ad8a8cd1252aee6
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SULF1 KCNIP3 PMFBP1

8.19e-041415835ef3166c5271aa90fd0633016edfe2c74b835319
ToppCellLPS-IL1RA-Hematopoietic_Mast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC18A2 RGS1 STAT4

8.36e-04142583f7d0d5ca9fc3dd929d4fdd59b71bfa623007e992
ToppCellLPS-IL1RA-Hematopoietic_Mast-Mast_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC18A2 RGS1 STAT4

8.36e-041425832a9a070e7c53ac593d46c6c5f6983f07d4413501
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KCNIP3 RGS1 STAT4

8.36e-04142583c2a3cd9998fd9a8e6b2665347ca5c32511776488
ToppCellcritical-Lymphoid-NKT|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ABCA13 DNAH5 DNAH7

8.54e-04143583dca035bfbfd1665c04076c43da8bc18a1502b9de
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

APBA2 CMAHP STAT4

8.89e-04145583a9f5a32abcf3eb2c66bd65f2521a6dd4ce56c635
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC18A2 RGS1 STAT4

9.06e-04146583a5c84ad44d6ffb25028a4fd5454fd5de81b16a5e
Diseasetype 1 diabetes mellitus (implicated_via_orthology)

GAD2 SLC18A2 STAT4

4.51e-0539523DOID:9744 (implicated_via_orthology)
Diseasealpha 1-antitrypsin deficiency (implicated_via_orthology)

SERPINI1 SERPINC1

6.36e-057522DOID:13372 (implicated_via_orthology)
DiseaseSeizures

GAD2 KARS1 HACE1 TRRAP

5.94e-04218524C0036572
Diseaseblood pressure

TNR RGS1

6.88e-0422522EFO_0004325
Diseaseurate measurement, bone density

LATS2 SULF1 EIF2AK4 CA10 DNAH14 JPH3

7.46e-04619526EFO_0003923, EFO_0004531
Diseaseserum gamma-glutamyl transferase measurement

TNPO1 CLUAP1 HACE1 MUC6 RYR2 PMFBP1 JPH3

1.06e-03914527EFO_0004532
Diseaseamino acid measurement

SERPINI1 CMAHP CA10 DNAH7 RYR2 PMFBP1

1.19e-03678526EFO_0005134
DiseaseAstigmatism

ABCA13 TNR DNAH5

1.54e-03129523HP_0000483

Protein segments in the cluster

PeptideGeneStartEntry
AALFMDHSGMLVMLP

EIF2AK4

1101

Q9P2K8
ALLDHMTGREMLVMY

ABCA3

1466

Q99758
EIQIEEYMRMMGVHP

ABCA13

3596

Q86UQ4
EYMRMMGVHPVIHFL

ABCA13

3601

Q86UQ4
VTHMMKEFPMDLYIR

ARMH3

456

Q5T2E6
EIHMKTMPAAMFRLL

APBA2

726

Q99767
MMLVVHMPRFRIEDG

SERPINC1

346

P01008
FGMDMKAYLRSMIPH

RGS1

46

Q08116
PDSHLMVLVERKYMG

MUC6

156

Q6W4X9
IMLMRLDSRLHTPMY

OR5M11

46

Q96RB7
PVIKARMMEYGTTMV

GAD2

531

Q05329
HMPMYLLLGQLSLMD

OR2AG2

56

A6NM03
MILLIHMDSRLHTPM

OR2T2

46

Q6IF00
VRPSGAMYLMVGIEM

TAT

366

P17735
DYIPGGDMMSLLIRM

LATS2

746

Q9NRM7
QMHALLAIALTMYPM

EIF3L

366

Q9Y262
RHRVMEVMPLMYDLK

PDPR

431

Q8NCN5
VYTLMPMVMADQHRS

HACE1

31

Q8IYU2
RPQLMVKHAMTMQPY

NIPBL

2016

Q6KC79
LLAITMEARLHMPMY

OR2AG1

46

Q9H205
MEARLHMPMYLLLGQ

OR2AG1

51

Q9H205
HMPMYLLLGQLSLMD

OR2AG1

56

Q9H205
MILLIHMDSRLHTPM

OR2T35

46

Q8NGX2
MEAMKYHLLPERRSM

KLHL4

401

Q9C0H6
NMVDYHLIMDMIPAI

NAT10

831

Q9H0A0
VTILIYLLMGEMHMV

PORCN

101

Q9H237
LMELTMLDYDMVHFP

CCNB1

326

P14635
MSTFGRMMVTPVELH

CYP24A1

246

Q07973
YMEPHMLGWRPLMLS

DNAH7

1751

Q8WXX0
HMKTMPAAMYRLLTA

APBA1

816

Q02410
SLFRPVAMMVPHYQM

DNAH14

1256

Q0VDD8
RFIMVMGAMLLVYLH

HERPUD2

301

Q9BSE4
MGPFMSILQEHIGVM

HEATR1

1841

Q9H583
VMNRMHVVSVPYALM

DIP2A

571

Q14689
IIMNKPVYITRMQMH

CA10

251

Q9NS85
MKSIYDMMGRHTYPI

KCNIP3

191

Q9Y2W7
MPHVMEVILPMLCSY

RYR2

3231

Q92736
PLLEYMASKAMMERH

DNAH5

1481

Q8TE73
GTILFMGRVMHPETM

SERPINI1

386

Q99574
HIIMANLYLLMPPTM

OR52N1

276

Q8NH53
MGQRMDLTKYIGMPH

PMFBP1

986

Q8TBY8
VLRFTQNMMMPIIHY

RTN4IP1

56

Q8WWV3
MRIAPELYHKMLVVG

KARS1

296

Q15046
TTMYPGMAHRMQKEI

POTEJ

966

P0CG39
NLRFMILMDGVHPEM

CMAHP

151

Q9Y471
EMMRALGYPRHISME

CLUAP1

11

Q96AJ1
MLVTVMMWPLAVYHR

RETREG3

196

Q86VR2
MAVFHDMLLQPLGMF

PLET1

1

Q6UQ28
QHARMSMMIRPEARY

KIF3B

641

O15066
MTYEGDPIPMQRTHM

STAT4

286

Q14765
VEMKMRPYNHRLMAG

TNR

1336

Q92752
LREYTLMELLVMHME

NRDC

931

O43847
QMGIEMQPYIPMVLH

TNPO1

746

Q92973
NLPMHLRRAYMSIMT

ZNFX1

706

Q9P2E3
LPVCKGMMEAMLYHI

GTF3C1

1996

Q12789
GMMEAMLYHIMTRPG

GTF3C1

2001

Q12789
SMMPIMGYLVDLRHV

SLC18A2

401

Q05940
SKRMYPHRPVMMVIS

SULF1

206

Q8IWU6
MQYTGPMLPIHMEFT

SULF1

261

Q8IWU6
HMRPLLMMLGDYRSL

TRRAP

1426

Q9Y4A5
IMRYTGPMKPIHMEF

SULF2

261

Q8IWU5
YRMEMKPLLRMETHP

JPH3

611

Q8WXH2
KSMLPEGVEMYRTVM

NACC2

456

Q96BF6