Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

LRP1 LRP2 LRP4 LTBP4 THBS1 NOTCH1 LTBP2 FBN1

1.18e-07749188GO:0005509
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LTBP4 TNC THBS1 LTBP2 FBN1

5.44e-07188185GO:0005201
GeneOntologyMolecularFunctiongrowth factor binding

LRP2 LTBP4 THBS1 LTBP2

1.01e-05156184GO:0019838
GeneOntologyMolecularFunctionproteoglycan binding

LRP1 TNC THBS1

1.25e-0551183GO:0043394
GeneOntologyMolecularFunctionintegrin binding

LTBP4 TNC THBS1 FBN1

1.58e-05175184GO:0005178
GeneOntologyMolecularFunctionglycosaminoglycan binding

LTBP4 THBS1 LTBP2 FBN1

8.37e-05268184GO:0005539
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 LRP2

9.14e-0516182GO:0005041
GeneOntologyMolecularFunctionapolipoprotein binding

LRP1 LRP4

1.44e-0420182GO:0034185
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 LRP2

1.60e-0421182GO:0030228
GeneOntologyMolecularFunctionsulfur compound binding

LRP1 THBS1 LTBP2 FBN1

1.72e-04323184GO:1901681
GeneOntologyMolecularFunctiontransforming growth factor beta binding

LTBP4 THBS1

2.46e-0426182GO:0050431
GeneOntologyMolecularFunctionfibronectin binding

TNC THBS1

5.29e-0438182GO:0001968
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

LRP1 LRP2

5.58e-0439182GO:0070325
GeneOntologyMolecularFunctionheparin binding

THBS1 LTBP2 FBN1

6.42e-04192183GO:0008201
GeneOntologyMolecularFunctionstructural molecule activity

LTBP4 TNC THBS1 LTBP2 FBN1

9.22e-04891185GO:0005198
GeneOntologyMolecularFunctioncell adhesion molecule binding

LTBP4 TNC THBS1 FBN1

1.75e-03599184GO:0050839
GeneOntologyMolecularFunctioncoreceptor activity

LRP1 LRP4

1.89e-0372182GO:0015026
GeneOntologyMolecularFunctionextracellular matrix binding

THBS1 LTBP2

1.94e-0373182GO:0050840
GeneOntologyMolecularFunctioncargo receptor activity

LRP1 LRP2

2.62e-0385182GO:0038024
GeneOntologyMolecularFunctioncytokine binding

LTBP4 THBS1

8.65e-03157182GO:0019955
GeneOntologyMolecularFunctionprotease binding

LRP1 THBS1

1.14e-02181182GO:0002020
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

LRP1 LRP2 LTBP4 THBS1 NOTCH1 LTBP2 FBN1

5.38e-08445187GO:0141091
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

LRP1 LRP2 LTBP4 THBS1 NOTCH1 LTBP2 FBN1

9.28e-08482187GO:0007178
GeneOntologyBiologicalProcessresponse to growth factor

LRP1 LRP2 LTBP4 TNC THBS1 NOTCH1 LTBP2 FBN1

3.26e-07883188GO:0070848
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

LRP1 LRP2 LTBP4 THBS1 NOTCH1 FBN1

3.40e-07347186GO:0090092
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

LRP1 LRP2 LTBP4 THBS1 NOTCH1 FBN1

9.28e-07412186GO:0090287
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

LRP1 LRP2 LRP4 LTBP4 THBS1 NOTCH1 LTBP2 FBN1

3.04e-061186188GO:0007167
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

LRP1 LTBP4 THBS1 LTBP2 FBN1

3.07e-06276185GO:0007179
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

LRP1 LRP2 LTBP4 THBS1 NOTCH1 LTBP2 FBN1

4.21e-06850187GO:0071363
GeneOntologyBiologicalProcessamyloid-beta clearance

LRP1 LRP2 LRP4

5.40e-0640183GO:0097242
GeneOntologyBiologicalProcesschemoattraction of axon

LRP1 LRP2

7.18e-065182GO:0061642
GeneOntologyBiologicalProcesspositive regulation of lysosomal protein catabolic process

LRP1 LRP2

7.18e-065182GO:1905167
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

LRP2 THBS1 NOTCH1 FBN1

7.60e-06150184GO:0090288
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

LRP1 LTBP4 THBS1 LTBP2 FBN1

8.01e-06336185GO:0071560
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

LRP1 LTBP4 THBS1 LTBP2 FBN1

8.86e-06343185GO:0071559
GeneOntologyBiologicalProcessnegative regulation of endothelial cell chemotaxis

THBS1 NOTCH1

1.51e-057182GO:2001027
GeneOntologyBiologicalProcesspositive regulation of protein catabolic process in the vacuole

LRP1 LRP2

1.51e-057182GO:1904352
GeneOntologyBiologicalProcessrenal system development

LRP2 LRP4 MECOM NOTCH1 FBN1

1.57e-05386185GO:0072001
GeneOntologyBiologicalProcessamyloid-beta clearance by cellular catabolic process

LRP1 LRP4

2.01e-058182GO:0150094
GeneOntologyBiologicalProcessregulation of transforming growth factor beta receptor signaling pathway

LRP1 LTBP4 THBS1 FBN1

2.01e-05192184GO:0017015
GeneOntologyBiologicalProcessregulation of cellular response to transforming growth factor beta stimulus

LRP1 LTBP4 THBS1 FBN1

2.14e-05195184GO:1903844
GeneOntologyBiologicalProcessheart development

LRP1 LRP2 MECOM THBS1 NOTCH1 FBN1

3.05e-05757186GO:0007507
GeneOntologyBiologicalProcesscoronary artery morphogenesis

LRP2 NOTCH1

3.22e-0510182GO:0060982
GeneOntologyBiologicalProcessnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

LRP1 LRP2 NOTCH1 FBN1

3.31e-05218184GO:0090101
GeneOntologyBiologicalProcessnegative regulation of cell-substrate adhesion

LRP1 THBS1 NOTCH1

3.48e-0574183GO:0010812
GeneOntologyBiologicalProcessnegative regulation of BMP signaling pathway

LRP2 NOTCH1 FBN1

4.40e-0580183GO:0030514
GeneOntologyBiologicalProcessaorta development

LRP1 LRP2 NOTCH1

4.40e-0580183GO:0035904
GeneOntologyBiologicalProcessregulation of lysosomal protein catabolic process

LRP1 LRP2

4.72e-0512182GO:1905165
GeneOntologyBiologicalProcesscoronary vasculature development

LRP1 LRP2 NOTCH1

4.91e-0583183GO:0060976
GeneOntologyBiologicalProcessregulation of protein catabolic process in the vacuole

LRP1 LRP2

6.51e-0514182GO:1904350
GeneOntologyBiologicalProcessartery morphogenesis

LRP1 LRP2 NOTCH1

6.68e-0592183GO:0048844
GeneOntologyBiologicalProcessoutflow tract morphogenesis

LRP2 THBS1 NOTCH1

7.12e-0594183GO:0003151
GeneOntologyBiologicalProcessnegative regulation of focal adhesion assembly

LRP1 THBS1

9.71e-0517182GO:0051895
GeneOntologyBiologicalProcessnegative regulation of cell-substrate junction organization

LRP1 THBS1

9.71e-0517182GO:0150118
GeneOntologyBiologicalProcesstube development

LRP1 LRP2 MECOM TNC THBS1 NOTCH1 FBN1

1.08e-041402187GO:0035295
GeneOntologyBiologicalProcessaxon development

LRP1 LRP2 LRP4 TNC NOTCH1

1.76e-04642185GO:0061564
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

LRP2 NOTCH1 FBN1

1.91e-04131183GO:0030510
GeneOntologyBiologicalProcesslysosomal protein catabolic process

LRP1 LRP2

1.96e-0424182GO:1905146
GeneOntologyBiologicalProcesstranscytosis

LRP1 LRP2

1.96e-0424182GO:0045056
GeneOntologyBiologicalProcessartery development

LRP1 LRP2 NOTCH1

1.99e-04133183GO:0060840
GeneOntologyBiologicalProcesscardiac septum development

LRP1 LRP2 NOTCH1

2.04e-04134183GO:0003279
GeneOntologyBiologicalProcessregulation of endothelial cell chemotaxis

THBS1 NOTCH1

2.31e-0426182GO:2001026
GeneOntologyBiologicalProcesskidney development

LRP2 LRP4 NOTCH1 FBN1

2.61e-04372184GO:0001822
GeneOntologyBiologicalProcesslipoprotein transport

LRP1 LRP2

2.68e-0428182GO:0042953
GeneOntologyBiologicalProcessprotein catabolic process in the vacuole

LRP1 LRP2

2.68e-0428182GO:0007039
GeneOntologyBiologicalProcesspericardium development

MECOM NOTCH1

2.68e-0428182GO:0060039
GeneOntologyBiologicalProcessnegative regulation of cell adhesion

LRP1 TNC THBS1 NOTCH1

2.69e-04375184GO:0007162
GeneOntologyBiologicalProcessembryonic limb morphogenesis

LRP4 MECOM NOTCH1

2.73e-04148183GO:0030326
GeneOntologyBiologicalProcessembryonic appendage morphogenesis

LRP4 MECOM NOTCH1

2.73e-04148183GO:0035113
GeneOntologyBiologicalProcesstube morphogenesis

LRP1 LRP2 MECOM TNC THBS1 NOTCH1

2.73e-041125186GO:0035239
GeneOntologyBiologicalProcessregulation of brown fat cell differentiation

MECOM FBN1

2.88e-0429182GO:0090335
GeneOntologyBiologicalProcesslipoprotein localization

LRP1 LRP2

2.88e-0429182GO:0044872
GeneOntologyBiologicalProcessreproductive structure development

LRP2 TNC ADAM30 NOTCH1

2.91e-04383184GO:0048608
GeneOntologyBiologicalProcessreproductive system development

LRP2 TNC ADAM30 NOTCH1

3.06e-04388184GO:0061458
GeneOntologyBiologicalProcessprostate gland epithelium morphogenesis

TNC NOTCH1

3.74e-0433182GO:0060740
GeneOntologyBiologicalProcessprostate gland morphogenesis

TNC NOTCH1

3.97e-0434182GO:0060512
GeneOntologyBiologicalProcesscoronary vasculature morphogenesis

LRP2 NOTCH1

3.97e-0434182GO:0060977
GeneOntologyBiologicalProcessendothelial cell chemotaxis

THBS1 NOTCH1

4.21e-0435182GO:0035767
GeneOntologyBiologicalProcessembryonic hindlimb morphogenesis

MECOM NOTCH1

4.21e-0435182GO:0035116
GeneOntologyBiologicalProcessheart formation

LRP2 NOTCH1

4.45e-0436182GO:0060914
GeneOntologyBiologicalProcessgrowth

LRP1 LRP4 LTBP4 TNC THBS1 NOTCH1

4.53e-041235186GO:0040007
GeneOntologyBiologicalProcessanimal organ morphogenesis

LRP2 LRP4 MECOM TNC THBS1 NOTCH1

5.23e-041269186GO:0009887
GeneOntologyBiologicalProcessappendage morphogenesis

LRP4 MECOM NOTCH1

5.25e-04185183GO:0035107
GeneOntologyBiologicalProcesslimb morphogenesis

LRP4 MECOM NOTCH1

5.25e-04185183GO:0035108
GeneOntologyBiologicalProcessnegative regulation of cell junction assembly

LRP1 THBS1

5.78e-0441182GO:1901889
GeneOntologyBiologicalProcessaorta morphogenesis

LRP1 NOTCH1

5.78e-0441182GO:0035909
GeneOntologyBiologicalProcessnegative regulation of Wnt signaling pathway

LRP1 LRP4 NOTCH1

6.11e-04195183GO:0030178
GeneOntologyBiologicalProcessBMP signaling pathway

LRP2 NOTCH1 FBN1

6.30e-04197183GO:0030509
GeneOntologyBiologicalProcessnegative regulation of cell-matrix adhesion

LRP1 THBS1

6.36e-0443182GO:0001953
GeneOntologyBiologicalProcessnegative regulation of cell migration involved in sprouting angiogenesis

THBS1 NOTCH1

7.28e-0446182GO:0090051
GeneOntologyBiologicalProcesscardiac chamber development

LRP1 LRP2 NOTCH1

7.79e-04212183GO:0003205
GeneOntologyBiologicalProcessapoptotic cell clearance

LRP1 THBS1

7.92e-0448182GO:0043277
GeneOntologyBiologicalProcessresponse to BMP

LRP2 NOTCH1 FBN1

8.12e-04215183GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

LRP2 NOTCH1 FBN1

8.12e-04215183GO:0071773
GeneOntologyBiologicalProcesshindlimb morphogenesis

MECOM NOTCH1

8.26e-0449182GO:0035137
GeneOntologyBiologicalProcessnegative regulation of ossification

LRP4 NOTCH1

8.60e-0450182GO:0030279
GeneOntologyBiologicalProcessdevelopmental growth

LRP1 LRP4 TNC THBS1 NOTCH1

8.80e-04911185GO:0048589
GeneOntologyBiologicalProcessregulation of neurogenesis

LRP1 LRP2 LRP4 NOTCH1

8.90e-04515184GO:0050767
GeneOntologyBiologicalProcesschemotaxis

LRP1 LRP2 THBS1 NOTCH1

9.03e-04517184GO:0006935
GeneOntologyBiologicalProcesslimb development

LRP4 MECOM NOTCH1

9.14e-04224183GO:0060173
GeneOntologyBiologicalProcessappendage development

LRP4 MECOM NOTCH1

9.14e-04224183GO:0048736
GeneOntologyBiologicalProcesstaxis

LRP1 LRP2 THBS1 NOTCH1

9.16e-04519184GO:0042330
GeneOntologyBiologicalProcessnegative regulation of chemotaxis

THBS1 NOTCH1

1.00e-0354182GO:0050922
GeneOntologyBiologicalProcesscirculatory system development

LRP1 LRP2 MECOM THBS1 NOTCH1 FBN1

1.03e-031442186GO:0072359
GeneOntologyBiologicalProcesspositive regulation of protein metabolic process

LRP1 LRP2 LRP4 THBS1 ASPSCR1 FBN1

1.09e-031458186GO:0051247
GeneOntologyBiologicalProcessendocardial cushion development

THBS1 NOTCH1

1.16e-0358182GO:0003197
GeneOntologyBiologicalProcessextracellular matrix assembly

LTBP4 NOTCH1

1.19e-0359182GO:0085029
GeneOntologyBiologicalProcessventricular cardiac muscle tissue morphogenesis

LRP2 NOTCH1

1.19e-0359182GO:0055010
GeneOntologyBiologicalProcessaxonogenesis

LRP1 LRP2 LRP4 NOTCH1

1.26e-03566184GO:0007409
GeneOntologyBiologicalProcessregeneration

LRP1 TNC NOTCH1

1.28e-03252183GO:0031099
GeneOntologyBiologicalProcessregulation of cell-substrate adhesion

LRP1 THBS1 NOTCH1

1.31e-03254183GO:0010810
GeneOntologyBiologicalProcessprostate gland development

TNC NOTCH1

1.32e-0362182GO:0030850
GeneOntologyBiologicalProcessbrown fat cell differentiation

MECOM FBN1

1.54e-0367182GO:0050873
GeneOntologyBiologicalProcesslung development

TNC NOTCH1 FBN1

1.55e-03269183GO:0030324
GeneOntologyCellularComponentmicrofibril

LTBP4 FBN1

4.83e-0513172GO:0001527
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LTBP4 TNC THBS1 LTBP2 FBN1

4.94e-05530175GO:0062023
GeneOntologyCellularComponentextracellular matrix

LTBP4 TNC THBS1 LTBP2 FBN1

1.36e-04656175GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LTBP4 TNC THBS1 LTBP2 FBN1

1.37e-04658175GO:0030312
GeneOntologyCellularComponentcell surface

LRP1 LRP2 LRP4 ADAM30 THBS1 NOTCH1

1.66e-041111176GO:0009986
GeneOntologyCellularComponentside of membrane

LRP1 LRP2 ADAM30 THBS1 ASPSCR1

5.16e-04875175GO:0098552
GeneOntologyCellularComponentaxonal growth cone

LRP1 LRP2

6.04e-0445172GO:0044295
GeneOntologyCellularComponentexternal side of plasma membrane

LRP1 LRP2 ADAM30 THBS1

6.91e-04519174GO:0009897
GeneOntologyCellularComponentreceptor complex

LRP1 LRP2 TAS1R3 NOTCH1

1.05e-03581174GO:0043235
GeneOntologyCellularComponentclathrin-coated pit

LRP1 LRP2

1.90e-0380172GO:0005905
GeneOntologyCellularComponentendoplasmic reticulum lumen

TNC THBS1 FBN1

2.29e-03332173GO:0005788
GeneOntologyCellularComponentcytoplasmic vesicle membrane

LRP1 LRP2 ADAM30 ASPSCR1 NOTCH1

3.11e-031307175GO:0030659
GeneOntologyCellularComponentvesicle membrane

LRP1 LRP2 ADAM30 ASPSCR1 NOTCH1

3.31e-031325175GO:0012506
GeneOntologyCellularComponentbasement membrane

TNC FBN1

4.34e-03122172GO:0005604
GeneOntologyCellularComponentpostsynaptic density

LRP1 LRP4 NOTCH1

5.42e-03451173GO:0014069
GeneOntologyCellularComponentasymmetric synapse

LRP1 LRP4 NOTCH1

6.33e-03477173GO:0032279
GeneOntologyCellularComponentpostsynaptic density membrane

LRP1 NOTCH1

7.08e-03157172GO:0098839
GeneOntologyCellularComponentpostsynaptic specialization

LRP1 LRP4 NOTCH1

7.32e-03503173GO:0099572
GeneOntologyCellularComponentneuron to neuron synapse

LRP1 LRP4 NOTCH1

8.15e-03523173GO:0098984
GeneOntologyCellularComponentsynaptic membrane

LRP1 LRP4 NOTCH1

1.10e-02583173GO:0097060
GeneOntologyCellularComponentpostsynaptic specialization membrane

LRP1 NOTCH1

1.14e-02201172GO:0099634
GeneOntologyCellularComponentapical part of cell

LRP1 LRP2 NOTCH1

1.14e-02592173GO:0045177
GeneOntologyCellularComponentendocytic vesicle membrane

LRP1 LRP2

1.26e-02212172GO:0030666
GeneOntologyCellularComponentendosome

LRP1 LRP2 ADAM30 NOTCH1

1.28e-021167174GO:0005768
GeneOntologyCellularComponentclathrin-coated vesicle

LRP1 LRP2

1.56e-02237172GO:0030136
HumanPhenoMicrospherophakia

LTBP2 FBN1

2.08e-054102HP:0030961
HumanPhenoIridodonesis

LTBP2 FBN1

3.46e-055102HP:0100693
HumanPhenoSpherophakia

LTBP2 FBN1

3.46e-055102HP:0034375
HumanPhenoPulmonic stenosis

LRP4 NOTCH1 LTBP2 FBN1

9.54e-05138104HP:0001642
HumanPhenoAbnormal pulmonary valve physiology

LRP4 NOTCH1 LTBP2 FBN1

1.83e-04163104HP:0031654
HumanPhenoShort finger

LRP4 MECOM NOTCH1 LTBP2 FBN1

1.98e-04325105HP:0009381
HumanPhenoCardiac valve calcification

NOTCH1 FBN1

2.67e-0413102HP:0005146
HumanPhenoAplasia/Hypoplasia of fingers

LRP4 MECOM NOTCH1 LTBP2 FBN1

3.47e-04366105HP:0006265
HumanPhenoAplasia/Hypoplasia of the lens

LTBP2 FBN1

3.59e-0415102HP:0008063
HumanPhenoAbnormal pulmonary valve morphology

LRP4 NOTCH1 LTBP2 FBN1

3.87e-04198104HP:0001641
MousePhenooverexpanded pulmonary alveolus

LRP2 LTBP4 FBN1

7.60e-0637153MP:0001183
MousePhenoemphysema

LRP2 LTBP4 FBN1

7.60e-0637153MP:0001958
MousePhenoabnormal heart ventricle morphology

LRP1 LRP2 LTBP4 MECOM THBS1 NOTCH1 FBN1

7.93e-06793157MP:0005294
MousePhenoheart right ventricle hypertrophy

LRP2 LTBP4 FBN1

1.12e-0542153MP:0000276
MousePhenoabnormal heart right ventricle wall morphology

LRP2 LTBP4 FBN1

2.14e-0552153MP:0031534
MousePhenoincreased heart right ventricle size

LRP2 LTBP4 FBN1

2.54e-0555153MP:0010563
MousePhenoabnormal heart septum morphology

LRP1 LRP2 LTBP4 MECOM THBS1

3.83e-05388155MP:0006113
MousePhenoincreased aorta wall thickness

LTBP4 FBN1

3.85e-059152MP:0010996
MousePhenoabnormal muscle morphology

LRP1 LRP2 LTBP4 MECOM THBS1 NOTCH1 FBN1

6.95e-051106157MP:0002108
MousePhenoabnormal artery morphology

LRP2 LTBP4 MECOM NOTCH1 FBN1

6.98e-05440155MP:0002191
MousePhenoabnormal lung vasculature morphology

MECOM THBS1 FBN1

7.25e-0578153MP:0004007
MousePhenoabnormal heart right ventricle size

LRP2 LTBP4 FBN1

7.25e-0578153MP:0010577
MousePhenoabnormal aorta morphology

LRP2 LTBP4 MECOM FBN1

7.76e-05225154MP:0000272
MousePhenoabnormal lung morphology

LRP2 LRP4 LTBP4 MECOM THBS1 FBN1

8.73e-05767156MP:0001175
MousePhenoabnormal aorta elastic fiber morphology

LTBP4 FBN1

9.71e-0514152MP:0003211
MousePhenosmall embryonic telencephalon

LRP2 MECOM

1.12e-0415152MP:0000936
MousePhenoabnormal limb bud morphology

LRP1 LRP4 MECOM

1.15e-0491153MP:0005650
MousePhenoabnormal cardiac muscle tissue morphology

LRP2 LTBP4 MECOM NOTCH1 FBN1

1.15e-04489155MP:0010630
MousePhenoabnormal pulmonary alveolus morphology

LRP2 LRP4 LTBP4 FBN1

1.26e-04255154MP:0002270
MousePhenoatelectasis

LRP2 LRP4 LTBP4

1.91e-04108153MP:0001177
MousePhenoabnormal dermal layer morphology

LTBP4 THBS1 FBN1

1.91e-04108153MP:0001243
MousePhenoabnormal pulmonary acinus morphology

LRP2 LRP4 LTBP4 FBN1

1.91e-04284154MP:0010911
MousePhenoabnormal respiratory system physiology

LRP2 LRP4 LTBP4 MECOM THBS1 FBN1

2.08e-04897156MP:0002133
MousePhenoabnormal pulmonary alveolar system morphology

LRP2 LRP4 LTBP4 FBN1

2.24e-04296154MP:0010899
MousePhenoabnormal aorta elastic tissue morphology

LTBP4 FBN1

2.45e-0422152MP:0009862
MousePhenoabnormal systemic artery morphology

LRP2 LTBP4 MECOM FBN1

2.48e-04304154MP:0011655
MousePhenoabnormal blood vessel elastic tissue morphology

LTBP4 FBN1

2.93e-0424152MP:0006083
MousePhenoabnormal spine curvature

LRP4 MECOM THBS1 FBN1

2.94e-04318154MP:0004174
MousePhenoincreased lung compliance

LTBP4 FBN1

3.44e-0426152MP:0010895
MousePhenoabnormal bone trabecula morphology

LRP4 MECOM FBN1

3.60e-04134153MP:0010867
MousePhenoabnormal thoracic aorta morphology

LRP2 MECOM FBN1

3.60e-04134153MP:0010468
MousePhenoabnormal trabecular bone connectivity density

LRP4 MECOM

3.71e-0427152MP:0010931
MousePhenoabnormal interventricular septum morphology

LRP2 LTBP4 MECOM THBS1

3.88e-04342154MP:0000281
MousePhenoabnormal axial skeleton morphology

LRP2 LRP4 LTBP4 MECOM THBS1 NOTCH1 FBN1

4.00e-041458157MP:0002114
MousePhenoabnormal limb development

LRP1 LRP4 MECOM

4.10e-04140153MP:0006279
MousePhenodiaphragmatic hernia

LRP1 FBN1

4.29e-0429152MP:0003924
MousePhenoabnormal respiratory system morphology

LRP2 LRP4 LTBP4 MECOM THBS1 FBN1

4.35e-041027156MP:0002132
MousePhenoabnormal heart valve physiology

NOTCH1 FBN1

4.59e-0430152MP:0011926
MousePhenohemorrhage

LRP1 MECOM THBS1 NOTCH1 FBN1

4.80e-04664155MP:0001914
MousePhenoabnormal tendon morphology

MECOM FBN1

4.91e-0431152MP:0005503
MousePhenoabnormal heart left ventricle morphology

LRP2 LTBP4 NOTCH1 FBN1

5.18e-04369154MP:0003921
MousePhenobrachydactyly

LRP4 MECOM

5.57e-0433152MP:0002544
MousePhenoabnormal heart right ventricle morphology

LRP2 LTBP4 FBN1

5.62e-04156153MP:0003920
MousePhenointernal hemorrhage

LRP1 THBS1 NOTCH1 FBN1

6.20e-04387154MP:0001634
MousePhenoabnormal bronchiole morphology

THBS1 FBN1

7.00e-0437152MP:0002267
MousePhenoabnormal metacarpal bone morphology

LRP4 FBN1

7.00e-0437152MP:0003073
MousePhenodecreased respiration

LRP2 LRP4 FBN1

7.22e-04170153MP:0014274
MousePhenoabnormal bone volume

LRP4 MECOM FBN1

7.60e-04173153MP:0010874
MousePhenoabnormal aorta tunica media morphology

LTBP4 FBN1

7.78e-0439152MP:0009873
MousePhenoincreased heart ventricle size

LRP2 LTBP4 FBN1

7.85e-04175153MP:0008772
MousePhenoabnormal myocardium layer morphology

LRP2 LTBP4 MECOM NOTCH1

7.98e-04414154MP:0005329
MousePhenoabnormal heart layer morphology

LRP2 LTBP4 MECOM NOTCH1

8.58e-04422154MP:0010545
MousePhenoabnormal lung compliance

LTBP4 FBN1

9.03e-0442152MP:0002333
MousePhenoabnormal heart size

LRP1 LRP2 LTBP4 MECOM NOTCH1 FBN1

9.17e-041180156MP:0005406
MousePhenosmall pharyngeal arch

MECOM NOTCH1

9.91e-0444152MP:0006346
MousePhenoabnormal vertebral column morphology

LRP4 MECOM THBS1 NOTCH1 FBN1

1.04e-03787155MP:0004703
MousePhenotrabecula carnea hypoplasia

MECOM NOTCH1

1.08e-0346152MP:0000295
MousePhenocardiac hypertrophy

LRP2 LTBP4 FBN1

1.09e-03196153MP:0001625
MousePhenoabnormal bone trabecular spacing

LRP4 MECOM

1.18e-0348152MP:0013629
MousePhenoabnormal aorta wall morphology

LTBP4 FBN1

1.28e-0350152MP:0009866
MousePhenonarrow eye opening

THBS1 IKZF2

1.28e-0350152MP:0005287
MousePhenoabnormal ear morphology

LRP2 MECOM NOTCH1 IKZF2

1.28e-03470154MP:0002102
MousePhenolimbs/digits/tail phenotype

LRP1 LRP2 LRP4 MECOM THBS1 FBN1

1.29e-031258156MP:0005371
MousePhenolung hemorrhage

THBS1 FBN1

1.38e-0352152MP:0001182
MousePhenolordosis

MECOM THBS1

1.38e-0352152MP:0000162
MousePhenoomphalocele

LRP1 LRP2

1.43e-0353152MP:0003052
MousePhenoabnormal blood circulation

LRP1 MECOM THBS1 NOTCH1 FBN1

1.44e-03845155MP:0002128
MousePhenorespiratory system inflammation

MECOM THBS1 FBN1

1.52e-03220153MP:0002405
MousePhenoabnormal pulmonary interalveolar septum morphology

LTBP4 FBN1

1.54e-0355152MP:0010900
MousePhenoabnormal trigeminal ganglion morphology

MECOM NOTCH1

1.54e-0355152MP:0001092
MousePhenodistended pericardium

MECOM NOTCH1

1.54e-0355152MP:0000292
MousePhenoimpaired hearing

LRP2 MECOM IKZF2

1.58e-03223153MP:0006325
MousePhenoabnormal pericardium morphology

MECOM NOTCH1 FBN1

1.62e-03225153MP:0000288
MousePhenoabnormal skin condition

MECOM THBS1 FBN1

1.66e-03227153MP:0001191
MousePhenoabnormal heart ventricle size

LRP2 LTBP4 FBN1

1.69e-03228153MP:0031543
MousePhenokyphosis

MECOM THBS1 FBN1

1.71e-03229153MP:0000160
MousePhenomyocardial trabeculae hypoplasia

MECOM NOTCH1

1.72e-0358152MP:0010503
MousePhenoabnormal neutrophil morphology

MECOM THBS1 ASPSCR1 FBN1

1.75e-03511154MP:0005065
MousePhenoabnormal eyelid aperture

THBS1 IKZF2

1.78e-0359152MP:0003671
MousePhenoabnormal jaw morphology

LRP2 LRP4 MECOM FBN1

2.00e-03530154MP:0000454
MousePhenoabnormal posture

LRP4 MECOM FBN1

2.02e-03243153MP:0001504
MousePhenocraniofacial phenotype

LRP1 LRP2 LRP4 MECOM NOTCH1 FBN1

2.03e-031372156MP:0005382
MousePhenoabnormal craniofacial morphology

LRP1 LRP2 LRP4 MECOM NOTCH1 FBN1

2.03e-031372156MP:0000428
DomainEGF_3

LRP1 LRP2 LRP4 LTBP4 TNC ADAM30 THBS1 NOTCH1 LTBP2 FBN1

3.29e-152351810PS50026
DomainEGF-like_dom

LRP1 LRP2 LRP4 LTBP4 TNC ADAM30 THBS1 NOTCH1 LTBP2 FBN1

5.90e-152491810IPR000742
DomainEGF_CA

LRP1 LRP2 LRP4 LTBP4 THBS1 NOTCH1 LTBP2 FBN1

6.10e-1586188PF07645
DomainEGF_1

LRP1 LRP2 LRP4 LTBP4 TNC ADAM30 THBS1 NOTCH1 LTBP2 FBN1

7.50e-152551810PS00022
DomainEGF-like_CS

LRP1 LRP2 LRP4 LTBP4 TNC ADAM30 THBS1 NOTCH1 LTBP2 FBN1

9.48e-152611810IPR013032
DomainEGF_2

LRP1 LRP2 LRP4 LTBP4 TNC ADAM30 THBS1 NOTCH1 LTBP2 FBN1

1.11e-142651810PS01186
DomainEGF_CA

LRP1 LRP2 LRP4 LTBP4 THBS1 NOTCH1 LTBP2 FBN1

1.09e-13122188SM00179
DomainEGF-like_Ca-bd_dom

LRP1 LRP2 LRP4 LTBP4 THBS1 NOTCH1 LTBP2 FBN1

1.24e-13124188IPR001881
DomainEGF

LRP1 LRP2 LRP4 LTBP4 TNC THBS1 NOTCH1 LTBP2 FBN1

2.99e-13235189SM00181
DomainGrowth_fac_rcpt_

LRP1 LRP2 LRP4 LTBP4 TNC NOTCH1 LTBP2 FBN1

8.06e-13156188IPR009030
DomainEGF_Ca-bd_CS

LRP1 LRP2 LRP4 LTBP4 NOTCH1 LTBP2 FBN1

2.48e-1297187IPR018097
DomainEGF_CA

LRP1 LRP2 LRP4 LTBP4 NOTCH1 LTBP2 FBN1

2.88e-1299187PS01187
DomainASX_HYDROXYL

LRP1 LRP2 LRP4 LTBP4 NOTCH1 LTBP2 FBN1

3.09e-12100187PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP1 LRP2 LRP4 LTBP4 NOTCH1 LTBP2 FBN1

4.69e-12106187IPR000152
DomainEGF

LRP1 LRP2 LRP4 TNC NOTCH1 LTBP2

1.45e-09126186PF00008
DomaincEGF

LRP1 LRP2 LRP4 FBN1

8.91e-0926184PF12662
DomaincEGF

LRP1 LRP2 LRP4 FBN1

8.91e-0926184IPR026823
DomainTB

LTBP4 LTBP2 FBN1

2.62e-087183PF00683
Domain-

LTBP4 LTBP2 FBN1

4.20e-0881833.90.290.10
DomainTB_dom

LTBP4 LTBP2 FBN1

6.29e-089183IPR017878
DomainTB

LTBP4 LTBP2 FBN1

6.29e-089183PS51364
DomainLdl_recept_b

LRP1 LRP2 LRP4

2.72e-0714183PF00058
DomainLDLRB

LRP1 LRP2 LRP4

2.72e-0714183PS51120
DomainEGF_extracell

LRP2 TNC NOTCH1 LTBP2

2.85e-0760184IPR013111
DomainEGF_2

LRP2 TNC NOTCH1 LTBP2

2.85e-0760184PF07974
DomainLY

LRP1 LRP2 LRP4

3.40e-0715183SM00135
DomainLDLR_classB_rpt

LRP1 LRP2 LRP4

3.40e-0715183IPR000033
Domain-

LRP1 LRP2 LRP4

6.72e-06391832.120.10.30
DomainLDLR_class-A_CS

LRP1 LRP2 LRP4

7.26e-0640183IPR023415
DomainLdl_recept_a

LRP1 LRP2 LRP4

1.04e-0545183PF00057
Domain-

LRP1 LRP2 LRP4

1.11e-05461834.10.400.10
Domain6-blade_b-propeller_TolB-like

LRP1 LRP2 LRP4

1.11e-0546183IPR011042
DomainLDLRA_1

LRP1 LRP2 LRP4

1.27e-0548183PS01209
DomainLDLa

LRP1 LRP2 LRP4

1.35e-0549183SM00192
DomainLDLRA_2

LRP1 LRP2 LRP4

1.35e-0549183PS50068
DomainLDrepeatLR_classA_rpt

LRP1 LRP2 LRP4

1.35e-0549183IPR002172
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LRP4 LTBP4 TNC THBS1 LTBP2 FBN1

3.76e-07300156M610
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

LTBP4 LTBP2 FBN1

4.75e-0632153MM14854
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LTBP4 TNC THBS1 LTBP2 FBN1

5.11e-06258155MM14572
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

LTBP4 LTBP2 FBN1

7.41e-0637153M27134
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

LTBP4 LTBP2 FBN1

8.04e-0638153MM14874
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

LTBP4 LTBP2 FBN1

8.71e-0639153MM14601
PathwayPID_INTEGRIN3_PATHWAY

TNC THBS1 FBN1

1.17e-0543153M53
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

LTBP4 LTBP2 FBN1

1.26e-0544153M26969
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

LTBP4 LTBP2 FBN1

1.54e-0547153M646
PathwayKEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA

LTBP4 FBN1

2.95e-058152M47850
PathwayPID_INTEGRIN1_PATHWAY

TNC THBS1 FBN1

4.28e-0566153M18
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

TNC THBS1 FBN1

6.54e-0576153MM14867
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

LTBP4 LTBP2 FBN1

6.80e-0577153MM14670
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

TNC THBS1 FBN1

9.14e-0585153M16441
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

LTBP4 LTBP2 FBN1

1.23e-0494153M1041
PathwayWP_AMPLIFICATION_AND_EXPANSION_OF_ONCOGENIC_PATHWAYS_AS_METASTATIC_TRAITS

TNC NOTCH1

1.42e-0417152M39443
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

LTBP4 LTBP2 FBN1

2.42e-04118153MM15588
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

LTBP2 FBN1

3.13e-0425152M39713
PathwayREACTOME_SYNDECAN_INTERACTIONS

TNC THBS1

3.65e-0427152M27217
PathwayPID_SYNDECAN_4_PATHWAY

TNC THBS1

5.15e-0432152M165
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

LTBP4 LTBP2 FBN1

6.01e-04161153M27871
PathwayREACTOME_SENSORY_PERCEPTION

LRP1 LRP2 TAS1R3

9.73e-04190153MM15687
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP1 LRP2

1.02e-0345152MM15344
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP1 LRP2

1.16e-0348152M27642
PathwayWP_MARKERS_OF_KIDNEY_CELL_LINEAGE

TNC NOTCH1

1.75e-0359152M46460
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

TNC THBS1

1.75e-0359152M27218
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

THBS1 FBN1

1.75e-0359152M39886
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

THBS1 NOTCH1

2.31e-0368152M27303
PathwayREACTOME_ECM_PROTEOGLYCANS

LRP4 TNC

2.88e-0376152M27219
PathwayKEGG_ECM_RECEPTOR_INTERACTION

TNC THBS1

3.50e-0384152M7098
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

LRP1 LRP2

4.19e-0392152MM14881
PathwayWP_COMPLEMENT_SYSTEM

LRP2 THBS1

4.55e-0396152M39581
PathwayWP_P53_TRANSCRIPTIONAL_GENE_NETWORK

THBS1 NOTCH1

4.55e-0396152M40062
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

LRP1 LRP2

4.93e-03100152M27158
PathwayWP_1P36_COPY_NUMBER_VARIATION_SYNDROME

LRP4 TAS1R3

6.14e-03112152M48072
PathwayWP_BURN_WOUND_HEALING

TNC FBN1

6.25e-03113152M42571
PathwayWP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES

LRP1 LRP2 LRP4

7.00e-03381153M48063
PathwayREACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS

TNC FBN1

7.02e-03120152MM14982
PathwayREACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS

TNC FBN1

7.48e-03124152M27285
PathwayWP_CELL_LINEAGE_MAP_FOR_NEURONAL_DIFFERENTIATION

TNC NOTCH1

8.44e-03132152M48110
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

THBS1 NOTCH1

9.84e-03143152M27275
Pubmed

Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.

LRP1 LRP2 THBS1

4.65e-1041837775583
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP1 LRP2 LRP4

1.16e-09518319047013
Pubmed

Proteomics characterization of extracellular space components in the human aorta.

LTBP4 TNC THBS1 LTBP2 FBN1

1.55e-0910118520551380
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

LTBP4 TNC THBS1 LTBP2 FBN1

9.98e-0914618527068509
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1 LRP2 LRP4

1.92e-081118324639464
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

LTBP4 TNC THBS1 LTBP2 FBN1

1.96e-0816718522159717
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

LTBP4 TNC THBS1 LTBP2 FBN1

2.47e-0817518528071719
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

LRP1 MECOM NOTCH1 FBN1 FAM193A

3.18e-0818418532908313
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

LRP1 LRP2 THBS1 FBN1

4.77e-087118433541421
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

TNC THBS1 LTBP2 FBN1

1.04e-078618428327460
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

LTBP4 TNC THBS1 LTBP2 FBN1

1.41e-0724818524006456
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

LRP1 LRP2 LRP4

1.54e-072118321337463
Pubmed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.

LTBP4 TNC LTBP2 FBN1

1.69e-079718427559042
Pubmed

Latent TGF-β binding protein 2 and 4 have essential overlapping functions in microfibril development.

LTBP4 LTBP2

2.53e-07218228252045
Pubmed

Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.

LRP1 LRP2

2.53e-07218234445520
Pubmed

High expression of intratumoral stromal proteins is associated with chemotherapy resistance in breast cancer.

TNC THBS1

2.53e-07218227487140
Pubmed

Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans.

LRP1 THBS1

2.53e-07218214991768
Pubmed

Antigen-induced regulation of T-cell motility, interaction with antigen-presenting cells and activation through endogenous thrombospondin-1 and its receptors.

LRP1 THBS1

2.53e-07218225393517
Pubmed

Exome sequencing identified new mutations in a Marfan syndrome family.

LRP1 FBN1

2.53e-07218224484584
Pubmed

Cellular internalization and degradation of thrombospondin-1 is mediated by the amino-terminal heparin binding domain (HBD). High affinity interaction of dimeric HBD with the low density lipoprotein receptor-related protein.

LRP1 THBS1

2.53e-0721829045712
Pubmed

Confocal microscopy demonstrates association of LTBP-2 in fibrillin-1 microfibrils and colocalisation with perlecan in the disc cell pericellular matrix.

LTBP2 FBN1

2.53e-07218224867584
Pubmed

Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1).

LRP1 THBS1

2.53e-07218217154366
Pubmed

Regulation of T-lymphocyte motility, adhesion and de-adhesion by a cell surface mechanism directed by low density lipoprotein receptor-related protein 1 and endogenous thrombospondin-1.

LRP1 THBS1

2.53e-07218224877199
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

LRP1 LTBP4 NOTCH1 FBN1

3.71e-0711818421078624
Pubmed

Thrombospondin 1 binding to calreticulin-LRP1 signals resistance to anoikis.

LRP1 THBS1

7.59e-07318218653767
Pubmed

LTBP-2 specifically interacts with the amino-terminal region of fibrillin-1 and competes with LTBP-1 for binding to this microfibrillar protein.

LTBP2 FBN1

7.59e-07318217293099
Pubmed

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.

LTBP4 FBN1

1.52e-06418212429738
Pubmed

Comparative immunolocalization of the elastin fiber-associated proteins fibrillin-1, LTBP-2, and MAGP-1 with components of the collagenous and proteoglycan matrix of the fetal human intervertebral disc.

LTBP2 FBN1

1.52e-06418221540769
Pubmed

Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.

LTBP4 LTBP2

1.52e-06418215611103
Pubmed

Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.

LRP1 LRP2

1.52e-06418212413896
Pubmed

Weill-Marchesani Syndrome

LTBP2 FBN1

1.52e-06418220301293
Pubmed

Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E.

LRP1 LRP2

1.52e-06418211421580
Pubmed

The latent transforming growth factor beta binding protein (LTBP) family.

LTBP4 LTBP2

1.52e-06418211104663
Pubmed

Congenital Diaphragmatic Hernia Overview

LRP2 LTBP4 FBN1

1.74e-064618320301533
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

TNC THBS1 FBN1

2.25e-065018323658023
Pubmed

ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association.

LRP1 LRP2

2.53e-06518216101684
Pubmed

DLL4/Notch1 and BMP9 Interdependent Signaling Induces Human Endothelial Cell Quiescence via P27KIP1 and Thrombospondin-1.

THBS1 NOTCH1

2.53e-06518226471266
Pubmed

Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.

LRP1 LRP2

2.53e-06518218685438
Pubmed

Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.

LTBP4 FBN1

3.79e-06618219349279
Pubmed

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein.

LRP1 LRP2

3.79e-0661829837937
Pubmed

Exploring functional candidate genes for genetic association in german patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma.

LTBP2 FBN1

3.79e-06618219182256
Pubmed

The tight-skin (Tsk) mutation is closely linked to B2m on mouse chromosome 2.

THBS1 FBN1

3.79e-0661828111131
Pubmed

Notch1 haploinsufficiency causes ascending aortic aneurysms in mice.

NOTCH1 FBN1

5.30e-06718229093270
Pubmed

Gene expression changes during the development of acute lung injury: role of transforming growth factor beta.

TNC THBS1

5.30e-06718216100012
Pubmed

Tenascin-C drives persistence of organ fibrosis.

TNC FBN1

5.30e-06718227256716
Pubmed

Polymorphisms in the transforming growth factor beta 1 pathway in relation to colorectal cancer progression.

LTBP4 THBS1

5.30e-06718219998449
Pubmed

Developmental expression of latent transforming growth factor beta binding protein 2 and its requirement early in mouse development.

LTBP2 FBN1

5.30e-06718210848613
Pubmed

Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta.

LTBP4 LTBP2

5.30e-06718210930463
Pubmed

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

LRP1 LRP2

5.30e-06718212169628
Pubmed

Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis.

TNC FBN1

7.07e-06818223055981
Pubmed

Retinal transcriptome of neonatal mice after optic nerve injury.

THBS1 FBN1

7.07e-06818237252932
Pubmed

APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice.

LRP1 LRP4

9.09e-06918223986861
Pubmed

Usp25m protease regulates ubiquitin-like processing of TUG proteins to control GLUT4 glucose transporter translocation in adipocytes.

LRP1 ASPSCR1

9.09e-06918229773651
Pubmed

LDL receptor-related protein as a component of the midkine receptor.

LRP1 LRP2

9.09e-06918210772929
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DPF1 LRP1 LRP2 LRP4 LTBP4 MECOM

1.44e-05111618631753913
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

LRP1 LRP2 NOTCH1

1.88e-0510118323382219
Pubmed

Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice.

LRP1 LRP4

1.97e-051318216207730
Pubmed

The Mohawk homeobox gene is a critical regulator of tendon differentiation.

TNC FBN1

1.97e-051318220498044
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

LRP1 LRP4 THBS1 NOTCH1 LTBP2 FBN1

2.18e-05120118635696571
Pubmed

bHLH gene expression in the Emx2-deficient dentate gyrus reveals defective granule cells and absence of migrating precursors.

TNC NOTCH1

2.29e-051418215084498
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

LRP1 LRP2

2.29e-051418217389516
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

LRP1 LRP2

2.29e-051418215082773
Pubmed

Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease.

LRP1 LRP4

2.65e-051518220205790
Pubmed

A primary expression map of the chromosome 15q15 region containing the recessive form of limb-girdle muscular dystrophy (LGMD2A) gene.

THBS1 FBN1

3.02e-05161827633422
Pubmed

Wnt signaling in the murine diastema.

LRP4 NOTCH1

3.42e-051718221531785
Pubmed

Role for ephrinB2 in postnatal lung alveolar development and elastic matrix integrity.

TNC FBN1

3.85e-051818218651661
Pubmed

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

LRP1 LRP2

3.85e-051818210827173
Pubmed

A Wnt/Notch/Pax7 signaling network supports tissue integrity in tongue development.

TNC NOTCH1

4.30e-051918228438836
Pubmed

Generation of Distal Renal Segments Involves a Unique Population of Aqp2 + Progenitor Cells.

LRP2 NOTCH1

4.30e-051918234667084
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

LTBP4 TNC FBN1

4.47e-0513518328675934
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

LRP1 LRP2 MECOM FAM193A

5.51e-0541818434709266
Pubmed

Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs.

TNC FBN1

5.81e-052218227527664
Pubmed

Netrin 1 directs vascular patterning and maturity in the developing kidney.

LTBP4 NOTCH1

6.36e-052318237818607
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

LTBP4 TNC FBN1

6.49e-0515318325037231
Pubmed

Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool.

TNC NOTCH1

6.94e-052418226116661
Pubmed

Deficient signaling via Alk2 (Acvr1) leads to bicuspid aortic valve development.

TNC NOTCH1

7.54e-052518222536403
Pubmed

Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.

MECOM THBS1

8.81e-052718224586749
Pubmed

Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.

LTBP4 MECOM LTBP2

1.00e-0417718322560297
Pubmed

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

LRP1 MECOM

1.09e-043018221946350
Pubmed

Heritable Thoracic Aortic Disease Overview

NOTCH1 FBN1

1.09e-043018220301299
Pubmed

Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening.

LRP1 NOTCH1

1.17e-043118232546759
Pubmed

TBX1 is required for normal stria vascularis and semicircular canal development.

THBS1 FBN1

1.17e-043118231550482
Pubmed

NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1.

TNC NOTCH1

1.24e-043218220610746
Pubmed

Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study.

LRP2 MECOM

1.24e-043218225189868
Pubmed

RUNX1 and TGF-β signaling cross talk regulates Ca2+ ion channels expression and activity during megakaryocyte development.

THBS1 LTBP2

1.49e-043518232281291
Pubmed

WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis.

LRP2 LRP4

1.49e-043518230940800
Pubmed

The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation.

DPF1 LRP2

1.49e-043518232504627
Pubmed

Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.

LTBP4 LTBP2

1.58e-043618220587546
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

TNC THBS1 NOTCH1

1.66e-0421018316537572
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

LTBP4 TNC NOTCH1 FBN1

1.70e-0456018421653829
Pubmed

HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2.

LRP2 NOTCH1

1.95e-044018223362348
Pubmed

Extracellular Hsp90α and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1.

LRP1 THBS1

2.36e-044418231273033
Pubmed

Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.

LRP1 LRP2

2.70e-044718211208732
Pubmed

Protein profile of exosomes from trabecular meshwork cells.

THBS1 LTBP2

2.93e-044918221362503
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

LRP1 TNC THBS1

3.00e-0425718316335952
Pubmed

Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.

THBS1 FBN1

3.30e-045218230389913
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

LRP1 LRP2

3.30e-045218226590417
Pubmed

Comparative mapping of 50 human chromosome 9 loci in the laboratory mouse.

TNC NOTCH1

3.43e-04531827774911
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

LRP1 LRP2 LRP4 THBS1 FBN1

3.91e-04128518535914814
Pubmed

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.

LRP1 MECOM

4.11e-045818223284291
InteractionNTN5 interactions

LRP2 LRP4 LTBP4 NOTCH1 FBN1

9.41e-1224175int:NTN5
InteractionZFP41 interactions

LRP1 LRP2 LRP4 LTBP4 FBN1

9.12e-1057175int:ZFP41
InteractionZNF74 interactions

LRP4 LTBP4 NOTCH1 LTBP2

1.58e-0834174int:ZNF74
InteractionZNF408 interactions

LRP2 LRP4 LTBP4 LTBP2 FBN1

1.04e-07145175int:ZNF408
InteractionZNF707 interactions

LRP4 LTBP4 NOTCH1 LTBP2

5.01e-0779174int:ZNF707
InteractionZDHHC15 interactions

LRP1 LRP2 THBS1 FBN1

3.15e-06125174int:ZDHHC15
InteractionTRIM37 interactions

LRP1 MECOM NOTCH1 FBN1 FAM193A ZNF554

8.40e-06630176int:TRIM37
InteractionANKRD36B interactions

LRP1 LRP2 LRP4

1.66e-0560173int:ANKRD36B
InteractionHRG interactions

LTBP4 THBS1 FBN1

1.92e-0563173int:HRG
InteractionFBN2 interactions

THBS1 LTBP2 FBN1

2.11e-0565173int:FBN2
InteractionIGFL3 interactions

LRP2 LRP4 NOTCH1

3.24e-0575173int:IGFL3
InteractionMBD1 interactions

LTBP4 TNC NOTCH1

3.51e-0577173int:MBD1
InteractionZNF778 interactions

LRP4 LTBP2

3.67e-0511172int:ZNF778
InteractionZNF563 interactions

LRP4 LTBP4

4.40e-0512172int:ZNF563
InteractionCALCR interactions

LRP1 THBS1

5.20e-0513172int:CALCR
InteractionIGSF5 interactions

LRP4 NOTCH1

6.06e-0514172int:IGSF5
InteractionCUBN interactions

LRP1 LRP2

6.99e-0515172int:CUBN
InteractionSCN3A interactions

LRP1 LRP2

7.98e-0516172int:SCN3A
InteractionDAB1 interactions

LRP1 LRP2 NOTCH1

9.37e-05107173int:DAB1
InteractionLRP5 interactions

LRP4 ADAM30 THBS1

9.90e-05109173int:LRP5
InteractionZNF224 interactions

LRP2 LRP4

1.26e-0420172int:ZNF224
InteractionCACNA1A interactions

LRP1 LTBP4 NOTCH1

1.42e-04123173int:CACNA1A
InteractionCFC1 interactions

LTBP4 THBS1 NOTCH1

1.52e-04126173int:CFC1
InteractionTHBS1 interactions

LRP1 LRP2 THBS1

1.56e-04127173int:THBS1
InteractionBRD1 interactions

DPF1 LRP1 LRP2 LRP4

1.67e-04344174int:BRD1
InteractionIKZF2 interactions

NOTCH1 IKZF2

2.15e-0426172int:IKZF2
InteractionTNFAIP6 interactions

LRP2 THBS1

2.32e-0427172int:TNFAIP6
InteractionPID1 interactions

LRP1 LRP4

2.32e-0427172int:PID1
InteractionFEZF1 interactions

LRP2 LRP4

2.50e-0428172int:FEZF1
InteractionZNF517 interactions

LRP2 LTBP4

2.68e-0429172int:ZNF517
InteractionFBXO2 interactions

LRP2 LTBP4 NOTCH1 FBN1

3.29e-04411174int:FBXO2
InteractionITGB1BP1 interactions

LRP1 LRP2

3.48e-0433172int:ITGB1BP1
InteractionANKS1B interactions

LRP1 LRP2

3.70e-0434172int:ANKS1B
InteractionLPL interactions

LRP1 LRP2

3.92e-0435172int:LPL
InteractionSOST interactions

LRP2 LRP4

3.92e-0435172int:SOST
InteractionDLK2 interactions

LRP2 NOTCH1

4.15e-0436172int:DLK2
InteractionLRPAP1 interactions

LRP1 LRP2 LRP4

4.35e-04180173int:LRPAP1
InteractionZNF17 interactions

LRP4 LTBP2

4.38e-0437172int:ZNF17
InteractionLDLRAP1 interactions

LRP1 LRP2

4.38e-0437172int:LDLRAP1
InteractionEMX2 interactions

LRP2 LRP4

4.87e-0439172int:EMX2
InteractionRAB4A interactions

LRP1 LRP2 LRP4 NOTCH1

4.91e-04457174int:RAB4A
InteractionCCN2 interactions

LRP1 LRP2

5.13e-0440172int:CCN2
InteractionJAG1 interactions

THBS1 NOTCH1

5.39e-0441172int:JAG1
InteractionAPBB1 interactions

LRP1 LRP2 NOTCH1

5.49e-04195173int:APBB1
InteractionLRP1 interactions

LRP1 THBS1 ASPSCR1

5.57e-04196173int:LRP1
InteractionZNF398 interactions

LRP4 LTBP2

5.93e-0443172int:ZNF398
InteractionDCN interactions

THBS1 FBN1

5.93e-0443172int:DCN
InteractionELANE interactions

LRP1 THBS1

7.08e-0447172int:ELANE
InteractionAPBA2 interactions

LRP1 LRP2

7.38e-0448172int:APBA2
InteractionDKK2 interactions

LRP2 NOTCH1

7.69e-0449172int:DKK2
InteractionWNT3A interactions

LRP1 NOTCH1

7.69e-0449172int:WNT3A
InteractionODAPH interactions

LTBP4 FBN1

7.69e-0449172int:ODAPH
InteractionFOXD4L6 interactions

LTBP4 NOTCH1

7.69e-0449172int:FOXD4L6
InteractionC9orf163 interactions

LTBP4 NOTCH1

8.33e-0451172int:C9orf163
InteractionKDM1A interactions

LRP1 LRP2 MECOM NOTCH1 FAM193A

8.49e-04941175int:KDM1A
InteractionMFAP5 interactions

LTBP4 FBN1

8.66e-0452172int:MFAP5
InteractionZNF669 interactions

LRP4 LTBP4

8.66e-0452172int:ZNF669
InteractionFOXF2 interactions

LRP1 ADAM30

9.34e-0454172int:FOXF2
InteractionSERPINE1 interactions

LRP1 LRP2

9.34e-0454172int:SERPINE1
InteractionSMOC1 interactions

LRP1 TNC

9.34e-0454172int:SMOC1
InteractionDYRK1A interactions

LRP2 LRP4 THBS1 FBN1

9.97e-04552174int:DYRK1A
InteractionCLU interactions

LRP1 LRP2 TNC

1.06e-03245173int:CLU
InteractionMAPK8IP1 interactions

LRP1 LRP2

1.08e-0358172int:MAPK8IP1
InteractionVPS39 interactions

MECOM NOTCH1

1.08e-0358172int:VPS39
InteractionZNF331 interactions

LRP4 LTBP4

1.27e-0363172int:ZNF331
InteractionCOL5A1 interactions

THBS1 FBN1

1.35e-0365172int:COL5A1
InteractionSPARC interactions

TNC THBS1

1.35e-0365172int:SPARC
InteractionLTBP4 interactions

LTBP4 LTBP2

1.43e-0367172int:LTBP4
InteractionANAPC10 interactions

LRP1 LRP2

1.48e-0368172int:ANAPC10
InteractionCNTN1 interactions

TNC NOTCH1

1.52e-0369172int:CNTN1
InteractionPRG2 interactions

LTBP4 THBS1 NOTCH1

1.64e-03285173int:PRG2
InteractionSNX17 interactions

LRP1 LRP2

2.09e-0381172int:SNX17
InteractionLTBP2 interactions

LTBP4 LTBP2

2.29e-0385172int:LTBP2
InteractionLRP1B interactions

LRP1 LRP2

2.29e-0385172int:LRP1B
InteractionSIRPD interactions

THBS1 NOTCH1

2.35e-0386172int:SIRPD
InteractionPDGFB interactions

LRP1 THBS1

2.46e-0388172int:PDGFB
InteractionASPSCR1 interactions

LRP1 ASPSCR1

2.51e-0389172int:ASPSCR1
InteractionZNF324B interactions

LTBP4 LTBP2

2.51e-0389172int:ZNF324B
InteractionLGALS1 interactions

LRP2 THBS1 NOTCH1

2.54e-03332173int:LGALS1
InteractionLAMB3 interactions

ADAM30 THBS1

2.57e-0390172int:LAMB3
InteractionMDK interactions

LRP1 LRP2

2.62e-0391172int:MDK
CytobandEnsembl 112 genes in cytogenetic band chr19q13

IGFLR1 DPF1 LTBP4

1.06e-021192183chr19q13
GeneFamilyLow density lipoprotein receptors

LRP1 LRP2 LRP4

1.05e-0713143634
GeneFamilyLatent transforming growth factor beta binding proteins

LTBP4 LTBP2

3.34e-064142628
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

MECOM IKZF2 ZNF554

1.64e-0271814328
CoexpressionNABA_ECM_GLYCOPROTEINS

LTBP4 TNC THBS1 LTBP2 FBN1

1.55e-07191185MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

LTBP4 TNC THBS1 LTBP2 FBN1

1.76e-07196185M3008
CoexpressionNABA_CORE_MATRISOME

LTBP4 TNC THBS1 LTBP2 FBN1

8.58e-07270185MM17057
CoexpressionNABA_CORE_MATRISOME

LTBP4 TNC THBS1 LTBP2 FBN1

9.39e-07275185M5884
CoexpressionAIZARANI_LIVER_C21_STELLATE_CELLS_1

LRP1 LTBP4 THBS1 FBN1

8.21e-06194184M39122
CoexpressionNABA_MATRISOME_HGSOC_OMENTAL_METASTASIS

TNC THBS1 LTBP2

8.63e-0659183M47993
CoexpressionGSE16450_CTRL_VS_IFNA_6H_STIM_MATURE_NEURON_CELL_LINE_UP

IGFLR1 TAS1R3 IKZF2 FBN1

9.08e-06199184M7420
CoexpressionGSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_DN

NOTCH1 LTBP2 IKZF2 FBN1

9.26e-06200184M9657
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

LRP1 TNC THBS1 FBN1

9.26e-06200184M5930
CoexpressionVERRECCHIA_RESPONSE_TO_TGFB1_C4

TNC THBS1

2.44e-0511182M566
CoexpressionBOQUEST_STEM_CELL_UP

LRP1 TNC LTBP2 FBN1

2.63e-05261184M1834
CoexpressionDESCARTES_FETAL_EYE_STROMAL_CELLS

LTBP4 THBS1 FBN1

3.18e-0591183M40180
CoexpressionNABA_MATRISOME

LTBP4 TNC ADAM30 THBS1 LTBP2 FBN1

3.97e-051008186MM17056
CoexpressionNABA_MATRISOME

LTBP4 TNC ADAM30 THBS1 LTBP2 FBN1

4.39e-051026186M5889
CoexpressionCUI_DEVELOPING_HEART_C3_FIBROBLAST_LIKE_CELL

LRP1 LTBP4 FBN1

6.74e-05117183M39300
CoexpressionZHANG_UTERUS_C0_SECRETORY_STROMAL3_NPPC_HIGH_CELL

LRP1 LTBP4 THBS1 FBN1

7.12e-05337184MM16606
CoexpressionCHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP

TNC THBS1 LTBP2

7.44e-05121183M12828
CoexpressionMURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL

TNC THBS1 NOTCH1 LTBP2 FBN1

7.55e-05681185M39175
CoexpressionCLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP

TNC THBS1

8.40e-0520182MM706
CoexpressionCLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP

TNC THBS1

8.40e-0520182M11701
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_OMD_POS_ENDOTHELIAL_CELL

LTBP4 MECOM THBS1 LTBP2

8.71e-05355184M45758
CoexpressionCHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP

TNC THBS1 LTBP2

9.64e-05132183MM465
CoexpressionDESCARTES_FETAL_THYMUS_STROMAL_CELLS

LRP1 LTBP4 FBN1

1.08e-04137183M40313
CoexpressionHALLMARK_COAGULATION

LRP1 THBS1 FBN1

1.10e-04138183M5946
CoexpressionJEON_SMAD6_TARGETS_UP

THBS1 FBN1

1.22e-0424182M4592
CoexpressionAZARE_STAT3_TARGETS

TNC THBS1

1.22e-0424182M2312
CoexpressionTARTE_PLASMA_CELL_VS_PLASMABLAST_UP

LRP1 TNC LTBP2 FBN1

1.35e-04398184M4872
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_AIRWAY_FIBROBLAST

MECOM TNC

1.55e-0427182M45665
CoexpressionNABA_MATRISOME_METASTATIC_LUNG_LYMPH_NODE_METASTASIS

TNC LTBP2

1.79e-0429182MM17055
CoexpressionBERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_DN

TNC THBS1

1.92e-0430182M3034
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2B

LRP1 LRP2 TNC NOTCH1

1.97e-04439184M39054
CoexpressionBERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_DN

TNC THBS1

2.18e-0432182MM472
CoexpressionVECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP

THBS1 LTBP2 FBN1

2.33e-04178183M17079
CoexpressionNABA_MATRISOME_PRIMARY_METASTATIC_LUNG_TUMOR

TNC LTBP2

2.61e-0435182MM17054
CoexpressionCLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN

LTBP2 FBN1

2.61e-0435182M11788
CoexpressionLIM_MAMMARY_STEM_CELL_UP

LRP1 LRP4 LTBP4 THBS1

2.75e-04479184M2573
CoexpressionCLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN

LTBP2 FBN1

2.77e-0436182MM1212
CoexpressionLIM_MAMMARY_STEM_CELL_UP

LRP1 LRP4 LTBP4 THBS1

2.84e-04483184MM1082
CoexpressionVERRECCHIA_DELAYED_RESPONSE_TO_TGFB1

TNC THBS1

2.92e-0437182M16643
CoexpressionCUI_DEVELOPING_HEART_VASCULAR_ENDOTHELIAL_CELL

LTBP4 MECOM LTBP2

2.96e-04193183M39321
CoexpressionGSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_20MIN_UP

LRP4 MECOM IKZF2

3.05e-04195183M6899
CoexpressionNABA_MATRISOME_POORLY_METASTATIC_MELANOMA

THBS1 LTBP2

3.09e-0438182M47982
CoexpressionGSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_52H_UP

LRP2 IKZF2 FBN1

3.28e-04200183M9633
CoexpressionGSE43955_1H_VS_20H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN

TNC IKZF2 FBN1

3.28e-04200183M9677
CoexpressionGSE15767_MED_VS_SCS_MAC_LN_UP

LRP1 LRP4 THBS1

3.28e-04200183M3584
CoexpressionGSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_DN

LRP2 TNC THBS1

3.28e-04200183M4386
CoexpressionCUI_DEVELOPING_HEART_C5_VALVAR_CELL

LTBP4 THBS1 LTBP2

3.53e-04205183M39302
CoexpressionPARK_HSC_MARKERS

MECOM NOTCH1

4.14e-0444182M6509
CoexpressionZHANG_UTERUS_C2_SECRETORY_STROMAL3_RAMP3_HIGH_CELL

LRP1 LTBP4 FBN1

4.87e-04229183MM16607
CoexpressionCHICAS_RB1_TARGETS_CONFLUENT

MECOM THBS1 LTBP2 FBN1

5.21e-04567184M2129
CoexpressionSASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION

LTBP2 FBN1

5.35e-0450182M1259
CoexpressionLUI_THYROID_CANCER_CLUSTER_1

LRP4 FBN1

5.79e-0452182M2135
CoexpressionSASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION

LTBP2 FBN1

5.79e-0452182MM1118
CoexpressionCHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN

TNC LTBP2

6.24e-0454182M5312
CoexpressionHALLMARK_TGF_BETA_SIGNALING

THBS1 LTBP2

6.24e-0454182M5896
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2A

LRP1 LRP2 TNC NOTCH1

6.44e-04600184M39055
CoexpressionCHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN

TNC LTBP2

6.95e-0457182MM463
CoexpressionKOYAMA_SEMA3B_TARGETS_UP

DPF1 THBS1 LTBP2

7.70e-04268183M12746
CoexpressionKUMAR_PATHOGEN_LOAD_BY_MACROPHAGES

LTBP4 ASPSCR1 ZNF554

8.21e-04274183M2538
CoexpressionOISHI_CHOLANGIOMA_STEM_CELL_LIKE_DN

LRP1 LTBP4 FBN1

8.21e-04274183M289
CoexpressionTRAVAGLINI_LUNG_MYOFIBROBLAST_CELL

TNC LTBP2

9.03e-0465182M41673
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_ARTERIAL_ENDOTHELIAL_CELL

LTBP4 MECOM FBN1

9.29e-04286183M45746
CoexpressionRUBENSTEIN_SKELETAL_MUSCLE_FBN1_FAP_CELLS

LRP1 LTBP4 FBN1

9.57e-04289183M41750
CoexpressionTRAVAGLINI_LUNG_ADVENTITIAL_FIBROBLAST_CELL

LRP1 LTBP4 FBN1

1.03e-03296183M41675
CoexpressionKUMAR_AUTOPHAGY_NETWORK

LTBP4 ZNF554

1.11e-0372182M2539
CoexpressionLEE_AGING_CEREBELLUM_DN

TNC THBS1

1.14e-0373182M1544
CoexpressionZHANG_UTERUS_C1_PROLIFERATIVE_STROMAL1_MGP_HIGH_CELL

LRP1 LTBP4 FBN1

1.17e-03310183MM16608
CoexpressionLEE_AGING_CEREBELLUM_DN

TNC THBS1

1.20e-0375182MM662
CoexpressionMULLIGHAN_NPM1_MUTATED_SIGNATURE_2_DN

LRP4 LTBP4

1.23e-0376182M8315
CoexpressionHELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS

LRP1 FBN1

1.26e-0377182M19128
CoexpressionWONG_ADULT_TISSUE_STEM_MODULE

LRP4 TNC THBS1 LTBP2

1.28e-03721184M1999
CoexpressionWONG_ENDMETRIUM_CANCER_DN

LTBP4 FBN1

1.30e-0378182M1311
CoexpressionTABULA_MURIS_SENIS_MAMMARY_GLAND_BASAL_CELL_AGEING

LRP1 LTBP4 THBS1

1.31e-03322183MM3786
CoexpressionGRESHOCK_CANCER_COPY_NUMBER_UP

MECOM ASPSCR1 NOTCH1

1.32e-03323183M9150
CoexpressionFAN_EMBRYONIC_CTX_ASTROCYTE_1

LRP4 TNC

1.33e-0379182M39033
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2C

LRP1 TNC NOTCH1

1.34e-03325183M39053
CoexpressionWARTERS_RESPONSE_TO_IR_SKIN

ASPSCR1 NOTCH1

1.47e-0383182M2600
CoexpressionONDER_CDH1_SIGNALING_VIA_CTNNB1

LTBP2 FBN1

1.50e-0384182M15484
CoexpressionKIM_GLIS2_TARGETS_UP

LTBP2 FBN1

1.57e-0386182M2259
CoexpressionLAKE_ADULT_KIDNEY_C28_INTERSTITIUM

TNC THBS1

1.57e-0386182M39247
CoexpressionLIU_VAV3_PROSTATE_CARCINOGENESIS_UP

TNC LTBP2

1.68e-0389182M215
CoexpressionJONES_OVARY_T_CELL

LTBP4 MECOM

1.76e-0391182M48354
CoexpressionMURARO_PANCREAS_ENDOTHELIAL_CELL

MECOM THBS1 NOTCH1

1.83e-03362183M39176
CoexpressionZHANG_UTERUS_C4_MYOFIBROBLAST

LTBP4 THBS1 FBN1

1.93e-03369183MM16610
CoexpressionRODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN

THBS1 LTBP2 IKZF2 FBN1

1.93e-03807184M16651
CoexpressionROVERSI_GLIOMA_COPY_NUMBER_UP

DPF1 LRP4

2.12e-03100182M11028
CoexpressionCAHOY_ASTROGLIAL

LRP2 LTBP2

2.12e-03100182M2807
CoexpressionKIM_GLIS2_TARGETS_UP

LTBP2 FBN1

2.20e-03102182MM1064
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MYOFIBROBLAST_2_CELL

LRP4 LTBP2

2.29e-03104182M45682
CoexpressionAtlasStromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4

LTBP4 TNC THBS1 FBN1

9.22e-0791184GSM777059_100
CoexpressionAtlasStromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4

LRP1 LTBP4 TNC THBS1 LTBP2 FBN1

1.40e-06455186GSM777055_500
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_500

LRP1 LRP2 LTBP4 THBS1 FBN1

1.78e-05408185gudmap_kidney_adult_RenalCapsule_500
CoexpressionAtlasStromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4

LRP1 LTBP4 TNC THBS1 FBN1

2.48e-05437185GSM777046_500
CoexpressionAtlasStromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4

LTBP4 TNC THBS1 LTBP2 FBN1

2.53e-05439185GSM777059_500
CoexpressionAtlasStromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3

LRP1 LTBP4 TNC THBS1 FBN1

2.70e-05445185GSM777043_500
CoexpressionAtlasStromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4

LTBP4 TNC THBS1 LTBP2 FBN1

2.85e-05450185GSM777063_500
CoexpressionAtlasStromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2

LRP1 LTBP4 TNC THBS1 FBN1

2.94e-05453185GSM777067_500
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_1000

LRP1 LRP2 LTBP4 THBS1 LTBP2 FBN1

3.02e-05778186gudmap_kidney_adult_RenalCapsule_1000
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000

LRP2 LRP4 MECOM TNC NOTCH1 FBN1

3.13e-05783186gudmap_kidney_P4_CapMesRenVes_Crym_1000
CoexpressionAtlasStromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5

LRP1 LTBP4 TNC THBS1 FBN1

3.37e-05466185GSM777050_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_200

LRP1 LTBP4 FBN1

4.34e-0582183gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_200
CoexpressionAtlasStromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5

LRP1 THBS1 FBN1

5.19e-0587183GSM777050_100
CoexpressionAtlasStromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4

LTBP4 TNC THBS1

6.96e-0596183GSM777063_100
CoexpressionAtlasStromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3

LTBP4 THBS1 FBN1

7.17e-0597183GSM777043_100
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500_k-means-cluster#2

LTBP4 MECOM THBS1

8.58e-05103183Facebase_RNAseq_e8.5_Paraxial Mesoderm_500_K2
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000

LRP2 LTBP4 MECOM TNC THBS1 IKZF2

1.05e-04973186Facebase_RNAseq_e9.5_Olfactory Placode_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000

LTBP4 MECOM TNC THBS1 LTBP2 FBN1

1.05e-04973186Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000

LRP2 LTBP4 MECOM TNC THBS1 IKZF2

1.07e-04976186Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000

LRP2 LTBP4 MECOM TNC THBS1 IKZF2

1.12e-04984186Facebase_RNAseq_e10.5_Olfactory Pit_1000
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_1000

MECOM NOTCH1 FBN1

1.16e-04114183gudmap_kidney_P3_CapMes_Crym_k2_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

LRP1 LTBP4 TNC FBN1

1.16e-04310184gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_k-means-cluster#3_top-relative-expression-ranked_1000

LRP1 TNC THBS1 FBN1

1.17e-04311184gudmap_dev gonad_e11.5_M_GonMes_Sma_k3_1000
CoexpressionAtlasdev gonad_e11.5_F_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

LRP1 TNC THBS1 FBN1

1.42e-04327184gudmap_dev gonad_e11.5_F_GonMes_Sma_k4_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_500

LRP1 LTBP4 FBN1

1.71e-04130183gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_500
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#5

DPF1 LTBP4 MECOM TAS1R3 THBS1

1.72e-04658185Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K5
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

LRP1 LTBP4 TNC FBN1

2.08e-04361184gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#5

DPF1 LTBP4 MECOM TAS1R3 THBS1

2.12e-04688185Facebase_RNAseq_e10.5_Mandibular Arch_2500_K5
CoexpressionAtlaskidney_adult_RenalCapsule_k-means-cluster#2_top-relative-expression-ranked_1000

LRP1 LTBP4 LTBP2 FBN1

2.26e-04369184gudmap_kidney_adult_RenalCapsule_k2_1000
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_500

LRP4 MECOM TNC NOTCH1

2.29e-04370184gudmap_kidney_P3_CapMes_Crym_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_500

LRP1 LTBP4 THBS1 FBN1

2.33e-04372184gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

LRP1 LTBP4 THBS1 FBN1

2.36e-04373184gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_200

LRP1 LTBP4 FBN1

2.41e-04146183gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_200
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#2_top-relative-expression-ranked_1000

LTBP4 TNC THBS1 FBN1

2.51e-04379184gudmap_developingLowerUrinaryTract_P1_bladder_B_1000_k2
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#5

DPF1 LTBP4 MECOM TAS1R3 THBS1

2.66e-04722185Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K5
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500

LRP1 LTBP4 FBN1

2.93e-04156183gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_500
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500

LRP2 LRP4 MECOM NOTCH1

3.02e-04398184gudmap_kidney_P4_CapMesRenVes_Crym_500
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5

DPF1 LTBP4 MECOM TAS1R3 THBS1

3.03e-04743185Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K5
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#2

DPF1 LTBP4 MECOM TAS1R3 THBS1

3.11e-04747185Facebase_RNAseq_e9.5_Maxillary Arch_2500_K2
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#2

DPF1 LTBP4 MECOM TAS1R3 THBS1

3.11e-04747185Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K2
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_1000

LRP4 MECOM TNC NOTCH1 FBN1

3.15e-04749185gudmap_kidney_P3_CapMes_Crym_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500

LRP1 LTBP4 FBN1

3.45e-04165183gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_500
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_200

LRP4 MECOM TNC

3.51e-04166183gudmap_kidney_P3_CapMes_Crym_200
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

LRP1 LTBP4 FBN1

3.64e-04168183gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k4_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

LRP1 LTBP4 TNC THBS1 FBN1

3.73e-04777185gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

LRP1 LTBP4 TNC THBS1 FBN1

4.10e-04793185gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_200

LRP4 MECOM NOTCH1

4.10e-04175183gudmap_kidney_P4_CapMesRenVes_Crym_200
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_1000

LRP2 MECOM THBS1 IKZF2 FAM193A

4.14e-04795185gudmap_developingKidney_e15.5_anlage of loop of Henle_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_500

LRP1 LTBP4 FBN1

4.60e-04182183gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_500
CoexpressionAtlasStromal Cells, BEC.MLN, gp38- CD31+, Lymph Node, avg-5

LTBP4 MECOM THBS1 LTBP2

5.06e-04456184GSM777032_500
CoexpressionAtlasStromal Cells, BEC.SLN, gp38- CD31+, Lymph Node, avg-4

LTBP4 MECOM THBS1 LTBP2

5.18e-04459184GSM777037_500
CoexpressionAtlasMesoderm Day 30_vs_Mesoderm Day 15-Confounder_removed-fold2.0_adjp0.05

LTBP2 FBN1

5.19e-0440182PCBC_ratio_MESO-30_vs_MESO-15_cfr-2X-p05
CoexpressionAtlasJC_fibro_top-relative-expression-ranked_1000_k-means-cluster#1

LRP1 THBS1 LTBP2 FBN1

5.40e-04464184JC_fibro_1000_K1
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000

LRP1 LRP4 TNC THBS1 FBN1

5.60e-04849185gudmap_dev gonad_e11.5_M_GonMes_Sma_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#4_top-relative-expression-ranked_200

LRP1 FBN1

5.73e-0442182gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k4_200
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_500

LTBP4 MECOM TNC THBS1

6.09e-04479184Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_500
CoexpressionAtlaskidney_adult_Mesangium_Meis_top-relative-expression-ranked_1000

LRP1 MECOM TNC THBS1 FBN1

6.33e-04872185gudmap_kidney_adult_Mesangium_Meis_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500

LTBP4 MECOM TNC THBS1

6.58e-04489184Facebase_RNAseq_e8.5_Paraxial Mesoderm_500
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#3_top-relative-expression-ranked_500

TNC FBN1

7.80e-0449182gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k3_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_500

LRP1 FBN1

9.46e-0454182gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k2_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000

LTBP4 MECOM TNC TAS1R3 THBS1

1.01e-03967185Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000
CoexpressionAtlaskidney_adult_RenalCapsule_k-means-cluster#1_top-relative-expression-ranked_500

LTBP4 THBS1 FBN1

1.03e-03240183gudmap_kidney_adult_RenalCapsule_k1_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

LRP2 LRP4 LTBP4 MECOM TNC

1.09e-03983185Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#4

LTBP4 MECOM TAS1R3

1.12e-03247183Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000_K4
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#1

LTBP4 MECOM THBS1

1.22e-03255183Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000_K1
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_k-means-cluster#4_top-relative-expression-ranked_200

LRP2 IKZF2

1.25e-0362182gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_200_k4
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_200

LRP4 NOTCH1

1.25e-0362182gudmap_kidney_P4_CapMesRenVes_Crym_k3_200
CoexpressionAtlasdev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_1000

TNC FBN1

1.29e-0363182gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k2_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000

LRP1 LTBP4 FBN1

1.37e-03265183gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_500_k-means-cluster#4

LTBP4 MECOM

1.45e-0367182Facebase_RNAseq_e9.5_Facial Mesenchyne_500_K4
CoexpressionAtlasMyeloid Cells, Mo.6C+II-.LN, F480+ Ly6c+ MHCII lo/+, Lymph Node, avg-3

LRP1 THBS1

1.50e-0368182GSM605875_100
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

DPF1 LTBP4 MECOM TAS1R3

1.53e-03614184Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K1
CoexpressionAtlasMyeloid Cells, Mo.6C+II-.Bl, Cd115+ B220- CD43+ Ly6C+ MHCII-, Blood, avg-3

LRP1 THBS1

1.54e-0369182GSM605872_100
CoexpressionAtlasBM Top 100 - saphenous vein

TNC THBS1

1.54e-0369182BM Top 100 - saphenous vein
CoexpressionAtlasBM Top 100 - stomach cardiac

MECOM THBS1

1.67e-0372182BM Top 100 - stomach cardiac
CoexpressionAtlasMyeloid Cells, MF.Lv, CD45+ F4/80+ CD11b+, Liver, avg-2

LRP1 THBS1

1.67e-0372182GSM854320_100
CoexpressionAtlaskidney_P2_CapMes_Crym_top-relative-expression-ranked_1000

LRP4 MECOM TNC THBS1

1.75e-03636184gudmap_kidney_P2_CapMes_Crym_1000
CoexpressionAtlaskidney_P0_CapMes_Crym_top-relative-expression-ranked_1000

LRP2 MECOM TNC THBS1

1.78e-03639184gudmap_kidney_P0_CapMes_Crym_1000
CoexpressionAtlaskidney_P0_CapMes_Crym_top-relative-expression-ranked_500

MECOM TNC THBS1

1.84e-03294183gudmap_kidney_P0_CapMes_Crym_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#1

LRP2 LTBP4 THBS1

1.86e-03295183Facebase_RNAseq_e10.5_Olfactory Pit_2500_K1
CoexpressionAtlasMyeloid Cells, DC.II+480lo.PC, F4/80lo MHC II+ CD11c+ CD115+, Peritoneal Cavity, avg-3

LRP1 THBS1

1.91e-0377182GSM854294_100
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

DPF1 LRP4 LTBP4 TAS1R3

1.93e-03654184Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlasMyeloid Cells, MF.Thio5.II-480int.PC, CD115+ MHCII- F480int SiglecF- CD11c+, Peritoneal Cavity, avg-3

LRP1 THBS1

2.11e-0381182GSM605865_100
CoexpressionAtlaskidney_e10.5_UretericTrunk_HoxB7_top-relative-expression-ranked_100

LRP2 MECOM

2.11e-0381182gudmap_kidney_e10.5_UretericTrunk_HoxB7_100
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_top-relative-expression-ranked_100

LRP2 MECOM

2.17e-0382182gudmap_kidney_e15.5_Podocyte_MafB_100
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4

DPF1 LTBP4 THBS1 FBN1 FAM193A

2.17e-031148185facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_2500_k-means-cluster#4

DPF1 LTBP4 MECOM TAS1R3

2.27e-03683184Facebase_RNAseq_e9.5_Olfactory Placode_2500_K4
CoexpressionAtlasMyeloid Cells, MF.Thio5.II-480hi.PC, CD115+ MHC II- F480hi Siglec F-, Peritoneal Cavity, avg-3

LRP1 THBS1

2.27e-0384182GSM605862_100
CoexpressionAtlasStromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2

THBS1 FBN1

2.32e-0385182GSM777067_100
CoexpressionAtlasMyeloid Cells, MF.II-480hi.PC, F4/80hi CD115hi CD11b+ MHC II- CD11c-, Peritoneal Cavity, avg-3

LRP1 THBS1

2.38e-0386182GSM605850_100
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_100

LRP2 MECOM

2.43e-0387182gudmap_kidney_P0_JuxtaGlom_Ren1_100
CoexpressionAtlasFetal Liver, SC.STSL.FL, IgM- CD24- CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Fetal Liver, avg-2

MECOM IKZF2

2.43e-0387182GSM791122_100
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_100

LRP4 MECOM

2.54e-0389182gudmap_kidney_P3_CapMes_Crym_100
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_100

LRP4 MECOM

2.54e-0389182gudmap_kidney_P4_CapMesRenVes_Crym_100
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#1

MECOM LTBP2 FBN1

2.69e-03336183ratio_EB_vs_SC_1000_K1
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000

LRP1 LTBP4 FBN1

2.69e-03336183gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

LRP1 TNC FBN1

2.71e-03337183gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlasFetal Liver, SC.LTSL.FL, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Fetal Liver, avg-3

MECOM IKZF2

2.72e-0392182GSM791126_100
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_500_k-means-cluster#4

LTBP4 MECOM

2.72e-0392182Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_500_K4
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#5

LTBP4 MECOM

2.72e-0392182Facebase_RNAseq_e9.5_Maxillary Arch_500_K5
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

LRP1 LRP4 LTBP4 TNC THBS1 LTBP2 FBN1

9.42e-13200187a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

LRP1 LRP4 LTBP4 TNC THBS1 FBN1

9.03e-111891860c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

LRP1 LTBP4 TNC THBS1 LTBP2 FBN1

1.06e-10194186d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LRP1 LRP4 LTBP4 TNC LTBP2 FBN1

1.23e-101991866b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LRP1 LRP4 LTBP4 TNC LTBP2 FBN1

1.23e-1019918638cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

LRP1 LRP4 LTBP4 TNC LTBP2 FBN1

1.27e-10200186a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

LRP1 LRP4 LTBP4 TNC THBS1 FBN1

1.27e-102001869d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

LRP1 LRP4 LTBP4 TNC LTBP2 FBN1

1.27e-1020018609537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LRP4 LTBP4 TNC LTBP2

7.74e-0917918502c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP4 LTBP4 TNC LTBP2 FBN1

8.19e-09181185b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LTBP4 MECOM TNC LTBP2 FBN1

9.13e-091851859f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LTBP4 MECOM TNC LTBP2 FBN1

9.64e-0918718513731298bc562ec29582f5da1b4c97261284f6f1
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LTBP4 MECOM TNC LTBP2 FBN1

9.64e-091871855258674d0346e5c51a4b965efcdc1790c970845d
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LTBP4 TAS1R3 THBS1 LTBP2 FBN1

9.90e-09188185b382d18fb09fb2869f3c151efa71540a7f5ed229
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

LRP1 LRP4 LTBP4 TNC FBN1

9.90e-091881853f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LTBP4 TNC THBS1 FBN1

1.02e-08189185e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellwk_15-18-Mesenchymal-Fibroblast-Airway_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

LTBP4 MECOM TNC LTBP2 FBN1

1.02e-081891854f9608b84d135268a17455661870c46ae8554a24
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LTBP4 TNC THBS1 FBN1

1.02e-081891852a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-mesenchymal_stem_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP4 THBS1 LTBP2 FBN1

1.04e-08190185d13fd234caa3fc69d8a59bc0060cdacdf716ee55
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

LTBP4 TNC THBS1 LTBP2 FBN1

1.07e-081911859bbafdf316c1fa3a9f1ee30d41dd7158b5c97279
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 LRP4 LTBP4 THBS1 FBN1

1.07e-081911855c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LTBP4 TNC THBS1 FBN1

1.07e-08191185b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 LTBP4 THBS1 LTBP2 FBN1

1.07e-081911854e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 LRP4 LTBP4 THBS1 FBN1

1.07e-0819118580484d39f34703a33b9bac09826b7a526e883cab
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LTBP4 TNC THBS1 FBN1

1.10e-08192185162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LTBP4 TNC THBS1 FBN1

1.10e-081921856f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

LRP1 MECOM TNC LTBP2 FBN1

1.10e-0819218560b1312e84f6d6448365a952469c506c00b5fe93
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LTBP4 TNC THBS1 FBN1

1.10e-081921853d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LTBP4 TNC THBS1 FBN1

1.10e-081921854e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LTBP4 TNC THBS1 FBN1

1.10e-08192185ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LTBP4 TNC THBS1 FBN1

1.10e-08192185f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LTBP4 TNC THBS1 FBN1

1.10e-08192185df1545670370fb1010c567cd059c2783eab315f7
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LTBP4 TNC LTBP2 FBN1

1.13e-08193185dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LTBP4 TNC LTBP2 FBN1

1.13e-08193185e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LTBP4 TNC LTBP2 FBN1

1.16e-0819418529f83cdd63314fff41258937d70b881a5503bfcc
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LTBP4 TNC THBS1 FBN1

1.16e-081941856e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LTBP4 TNC LTBP2 FBN1

1.16e-08194185d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LTBP4 TNC THBS1 FBN1

1.16e-0819418589b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

LRP1 LTBP4 MECOM LTBP2 FBN1

1.16e-08194185234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LTBP4 TNC LTBP2 FBN1

1.19e-0819518547762d9e442fb1f6f0033e3e10f4c6e498d2c081
ToppCellCOVID-19-Heart-Low_count_Fib|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP1 LTBP4 THBS1 LTBP2 FBN1

1.19e-08195185e09590d1f51d5fa57fceb84c9f48f84b23d4d224
ToppCellP07-Mesenchymal|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP1 TNC THBS1 LTBP2 FBN1

1.19e-08195185859764b605866b6c3e6edd0698670ca9c0f20745
ToppCellP03-Mesenchymal|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP1 LTBP4 TNC THBS1 FBN1

1.19e-081951856180309c6ae278b996fd98c57461cbc129c028ba
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LRP2 LRP4 LTBP4 FBN1

1.22e-081961856bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellPND10-Mesenchymal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 TNC THBS1 LTBP2 FBN1

1.22e-08196185ace167a40adb7022b365be3c2b1cbd4ba963739a
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LRP2 LRP4 LTBP4 FBN1

1.22e-08196185c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.25e-08197185fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellwk_20-22-Mesenchymal-Fibroblast-Airway_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LTBP4 MECOM TNC LTBP2 FBN1

1.25e-08197185233caeee200ca905900226f85426e084caf290fb
ToppCellPND14-Mesenchymal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 LTBP4 TNC LTBP2 FBN1

1.25e-081971859a14bc2e7d6081e2ab0e2e5555fc8804f13d3dbe
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LTBP4 TNC LTBP2 FBN1

1.25e-081971854cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.32e-08199185ba586690f88fd051f449753bfe7603a2cb431782
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.32e-0819918530d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.32e-08199185e1849505b92820a219c5a2c35492bdd55579fb48
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.32e-0819918538ed3bc7daa993d9edcf3e7834597ebb06dd24f8
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.32e-0819918506a7d874ff7c4616577f6e59d3118717a8c47c00
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.32e-08199185fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.32e-08199185a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts|LPS_only / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.32e-081991851a0add79f4e34078b3475eb11c85a4234bda197c
ToppCellLPS_only-Mesenchymal_fibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.32e-08199185211c3a08f2d484ab7a3368006767289088f0d957
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.35e-082001859b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.35e-08200185ab4fda0cc95cb8f80ea9f28745013f3248def820
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.35e-0820018544a68bacdb3d5bf563bd35952176995850933a81
ToppCell5'-Adult-Distal_Rectal-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 LTBP4 THBS1 LTBP2 FBN1

1.35e-08200185db6281b5d4032116310db379d9175d790994c99c
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.35e-08200185b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.35e-0820018550ca6550998e461ef26dd670351060bd940765a8
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.35e-08200185a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 LTBP4 THBS1 LTBP2 FBN1

1.35e-08200185a2bb67a06757f19be3f56f8cb5bb7e2affa5f4ed
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LTBP4 TNC THBS1 LTBP2 FBN1

1.35e-08200185c5d818203bef80ff97c2e0158cf61970673dd258
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.35e-08200185dc61016c61729f69649cfb21f6264e685ce83dea
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LRP1 LTBP4 TNC THBS1 FBN1

1.35e-082001853bdba9612cd7c612b76aa9abecc4a6529aabfc1c
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 LTBP4 THBS1 LTBP2 FBN1

1.35e-0820018510f0c20ba7c71d9e2e177597f85b41cb40f0d878
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LTBP4 LTBP2 FBN1

5.91e-071711845d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellwk_08-11-Mesenchymal-Fibroblast-Airway_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LRP1 LTBP4 TNC FBN1

6.19e-07173184b23b408acc29a667cce104429afef1a6cf2720a5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DPF1 TNC THBS1 FBN1

6.49e-07175184f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DPF1 TNC THBS1 FBN1

6.49e-07175184910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LTBP4 LTBP2 FBN1

6.49e-07175184795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TNC LTBP2 FBN1

6.63e-071761849bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 TNC LTBP2 FBN1

6.63e-071761843f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellP28-Mesenchymal-mesenchymal_fibroblast|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP1 LRP4 LTBP4 FBN1

7.42e-07181184091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LTBP4 TNC FBN1

7.42e-07181184c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LTBP4 TNC FBN1

7.42e-07181184c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRP4 TNC THBS1 LTBP2

7.58e-07182184ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellP28-Mesenchymal|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP1 LRP4 LTBP4 FBN1

7.58e-0718218469f9d44694fe4f55a971ae0ac5dc3e7448ee78f3
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 LTBP4 TNC FBN1

7.58e-071821843dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 LTBP4 LTBP2 FBN1

7.58e-07182184d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCellfacs-Spleen-nan-18m-Lymphocytic-Cd3e_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFLR1 TNC NOTCH1 IKZF2

7.58e-07182184da3e9093cba791c7c282eb044656046252a32789
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

MECOM TNC LTBP2 FBN1

7.58e-07182184fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LRP4 TNC LTBP2

7.75e-071831847eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP4 LTBP4 LTBP2 FBN1

7.75e-0718318406a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP4 ADAM30 FBN1

7.92e-071841843bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

LRP1 LRP4 LTBP4 THBS1

7.92e-07184184684d05340a3dfb8aa08b881516a37f9627a10448
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 LRP4 LTBP4 TNC

8.09e-071851843b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MECOM TNC LTBP2 FBN1

8.09e-071851847dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TNC THBS1 LTBP2 FBN1

8.09e-07185184427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP1 TNC LTBP2 FBN1

8.09e-071851848f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LTBP4 MECOM TNC FBN1

8.09e-071851841ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP4 TNC FBN1

8.27e-0718618494d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LTBP4 THBS1 LTBP2 FBN1

8.27e-071861845473283fb95cee556b1f6934cf72169b676b5bcc
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LTBP4 MECOM TNC FBN1

8.27e-071861844d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

LRP1 LTBP4 LTBP2 FBN1

8.45e-071871844ea486991f66c29728d127171a07b81404ec0b78
ComputationalECM and collagens.

IGFLR1 LRP1 TNC THBS1 LTBP2 FBN1

2.05e-07225146MODULE_47
ComputationalMetal / Ca ion binding.

LRP1 LTBP2 FBN1

6.10e-04133143MODULE_324
ComputationalOvary genes.

LRP1 TNC LTBP2 FBN1

1.03e-03368144MODULE_1
ComputationalDRG (dorsal root ganglia) genes.

LRP1 TNC LTBP2 FBN1

1.21e-03384144MODULE_2
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

LTBP4 MECOM

1.86e-0350142GAVISH_3CA_METAPROGRAM_ENDOTHELIAL_NOTCH_SIGNALING
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

TNC THBS1

1.86e-0350142GAVISH_3CA_MALIGNANT_METAPROGRAM_13_EMT_2
Drugmonatepil

LRP1 LRP2 LRP4

1.50e-0629183CID000060810
Drugpyrachlostrobin

LRP2 LRP4 TNC THBS1 NOTCH1 LTBP2 FBN1

1.60e-06811187ctd:C513428
Drugfuniferine N-oxide

LTBP4 LTBP2 FBN1

7.47e-0649183CID000191631
Drug1-anilino-4-methyl-2-methylthio-4-phenylimidazolin-5-one

LRP2 TNC THBS1 NOTCH1 FBN1

8.26e-06373185ctd:C540355
DrugSulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A

LTBP4 MECOM LTBP2 FBN1

1.48e-051961843847_UP
DrugF0447-0125; Up 200; 10uM; PC3; HT_HG-U133A

IGFLR1 DPF1 LRP1 LTBP4

1.48e-051961846401_UP
DrugPropidium iodide [25535-16-4]; Up 200; 6uM; MCF7; HT_HG-U133A

LRP2 THBS1 ASPSCR1 LTBP2

1.51e-051971846277_UP
DrugFenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; PC3; HT_HG-U133A

DPF1 LRP1 LRP2 LTBP4

1.61e-052001843714_UP
Drugcoprogen

LRP1 LRP2

2.12e-059182CID006323272
Drug25-azacoprostane

LRP1 LRP2

2.65e-0510182CID000162243
Drugpitavastatin

LRP1 LRP2 LRP4

9.44e-05114183CID005282451
DrugHepI

TNC THBS1

1.11e-0420182CID003036968
DrugEpi Lovastatin

LRP1 LRP2 LRP4 THBS1

1.28e-04341184CID000003962
DrugHymecromone

TNC FBN1

1.75e-0425182ctd:D006923
Drugezetimibe

LRP1 LRP2 LRP4

2.00e-04147183CID000150311
Drugsimvastatin

LRP1 LRP2 LRP4 THBS1

2.14e-04390184CID000054454
Drugtetrahydroaldosterone-3-glucuronide

LRP1 LRP2

2.37e-0429182CID000167918
Drugsodium cholate

LRP1 LRP2 LRP4 THBS1

2.55e-04408184CID000000303
Drug25-hydroxycholesterol

LRP1 LRP2 LRP4

2.57e-04160183CID000065094
Drugprobucol

LRP1 LRP2 LRP4

2.67e-04162183CID000004912
Drug2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide

THBS1 FBN1

2.71e-0431182ctd:C577942
Drugpimobendan

TNC ASPSCR1

2.89e-0432182CID000004823
DruguPA inhibitor

LRP1 LRP2

2.89e-0432182CID000001746
DrugAC1NAG0I

LTBP4 LTBP2

2.89e-0432182CID004476319
DrugTetrahydrozoline hydrochloride [522-48-5]; Up 200; 16.8uM; HL60; HT_HG-U133A

LRP1 THBS1 FBN1

3.35e-041751832507_UP
Drugbeta-Naphthoflavone

LRP2 TNC THBS1 NOTCH1 LTBP2

3.63e-04828185ctd:D019324
DrugAC1L9GQC

TNC THBS1

3.87e-0437182CID000444689
DrugMonensin sodium salt [22373-78-0]; Down 200; 5.8uM; PC3; HT_HG-U133A

THBS1 NOTCH1 FBN1

4.06e-041871837402_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A

MECOM THBS1 ASPSCR1

4.26e-041901835223_DN
Drug0393-0188; Up 200; 10uM; PC3; HT_HG-U133A

TNC THBS1 ASPSCR1

4.39e-041921837536_UP
DrugCotinine (-) [486-56-6]; Down 200; 22.6uM; PC3; HT_HG-U133A

LRP1 THBS1 FBN1

4.46e-041931834650_DN
DrugOxalamine citrate salt [1949-20-8]; Up 200; 9.2uM; MCF7; HT_HG-U133A

DPF1 LTBP4 THBS1

4.46e-041931833344_UP
Drugtrifluoperazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A

LRP2 LTBP4 TNC

4.46e-041931835584_DN
DrugCimetidine [51481-61-9]; Down 200; 15.8uM; MCF7; HT_HG-U133A

LRP2 NOTCH1 LTBP2

4.46e-041931831464_DN
DrugSulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A

DPF1 LRP2 TNC

4.52e-041941833422_UP
DrugPhenelzine sulfate [156-51-4]; Up 200; 17uM; PC3; HT_HG-U133A

LRP1 LRP2 LRP4

4.52e-041941834538_UP
DrugDiethylstilbestrol [56-53-1]; Up 200; 15uM; PC3; HT_HG-U133A

DPF1 LTBP4 ADAM30

4.52e-041941833812_UP
DrugGliquidone [33342-05-1]; Up 200; 7.6uM; HL60; HT_HG-U133A

LRP2 THBS1 LTBP2

4.52e-041941833126_UP
DrugTrichlormethiazide [133-67-5]; Up 200; 10.6uM; HL60; HT_HG-U133A

DPF1 LRP2 FBN1

4.52e-041941832998_UP
Drug15d-PGJ2; Down 200; 10uM; PC3; HT_HG-U133A

IGFLR1 LTBP4 THBS1

4.52e-041941834455_DN
DrugPridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; MCF7; HT_HG-U133A

LTBP4 TNC THBS1

4.59e-041951833456_UP
DrugChlorambucil [305-03-3]; Down 200; 13.2uM; MCF7; HT_HG-U133A

LTBP4 THBS1 LTBP2

4.59e-041951834345_DN
DrugST021200; Up 200; 10uM; PC3; HT_HG-U133A

IGFLR1 MECOM NOTCH1

4.59e-041951837559_UP
Drug15d-PGJ2; Down 200; 10uM; MCF7; HT_HG-U133A

IGFLR1 MECOM NOTCH1

4.59e-041951835591_DN
DrugAzapropazone [13539-59-8]; Down 200; 13.4uM; MCF7; HT_HG-U133A

LRP2 THBS1 LTBP2

4.59e-041951836522_DN
DrugFusaric acid [536-69-6]; Up 200; 22.4uM; PC3; HT_HG-U133A

LRP4 LTBP4 ASPSCR1

4.66e-041961833986_UP
DrugFamprofazone [22881-35-2]; Up 200; 10.6uM; HL60; HT_HG-U133A

DPF1 LRP2 THBS1

4.66e-041961832174_UP
DrugEthaverine hydrochloride [985-13-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A

DPF1 ASPSCR1 FBN1

4.66e-041961833375_UP
DrugErgocryptine-alpha [511-09-1]; Up 200; 7uM; PC3; HT_HG-U133A

LRP1 LTBP4 MECOM

4.66e-041961833817_UP
DrugLactobionic acid [96-82-2]; Down 200; 11.2uM; PC3; HT_HG-U133A

TNC THBS1 NOTCH1

4.66e-041961836605_DN
DrugPhthalylsulfathiazole [85-73-4]; Up 200; 10uM; MCF7; HT_HG-U133A

LRP4 LTBP4 LTBP2

4.66e-041961833371_UP
Drughaloperidol; Down 200; 10uM; MCF7; HT_HG-U133A

LRP2 LTBP4 TNC

4.66e-041961835604_DN
DrugAG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A

LTBP4 MECOM TNC

4.66e-041961836435_UP
Drugclozapine; Up 200; 10uM; PC3; HT_HG-U133A

DPF1 LRP4 MECOM

4.66e-041961834453_UP
DrugBeta-sistosterol [83-46-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A

DPF1 LTBP4 THBS1

4.66e-041961834154_UP
DrugIsosorbide dinitrate [87-33-2]; Up 200; 17uM; PC3; HT_HG-U133A

LRP2 LTBP4 ASPSCR1

4.66e-041961833720_UP
DrugRapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A

MECOM THBS1 LTBP2

4.73e-041971836180_UP
DrugMycophenolic acid [24280-93-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A

LTBP4 MECOM THBS1

4.73e-041971834137_DN
DrugThioridazine hydrochloride [130-61-0]; Down 200; 9.8uM; MCF7; HT_HG-U133A

LRP2 MECOM LTBP2

4.73e-041971831486_DN
DrugDeoxycorticosterone [64-85-7]; Down 200; 12.2uM; PC3; HT_HG-U133A

LRP1 TNC THBS1

4.73e-041971836758_DN
DrugTrimethadione [127-48-0]; Up 200; 28uM; MCF7; HT_HG-U133A

DPF1 LTBP4 THBS1

4.73e-041971834165_UP
DrugDiloxanide furoate [3736-81-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A

LTBP4 TNC THBS1

4.73e-041971833399_DN
DrugBetulinic acid [472-15-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A

DPF1 LTBP4 FBN1

4.73e-041971834181_UP
DrugIndapamide [26807-65-8]; Up 200; 10.6uM; HL60; HT_HG-U133A

LRP2 THBS1 FBN1

4.73e-041971832361_UP
DrugAmiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; HL60; HT_HG-U133A

LRP1 MECOM FBN1

4.73e-041971833000_UP
DrugTamoxifen citrate [54965-24-1]; Down 200; 7uM; MCF7; HT_HG-U133A

LRP2 LTBP4 THBS1

4.73e-041971832212_DN
DrugIpratropium bromide [22254-24-6]; Up 200; 9.8uM; PC3; HT_HG-U133A

LRP4 TNC FBN1

4.73e-041971835823_UP
DrugGlipizide [29094-61-9]; Down 200; 9uM; MCF7; HT_HG-U133A

LRP2 ASPSCR1 LTBP2

4.73e-041971831508_DN
DrugClozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A

DPF1 MECOM FBN1

4.73e-041971835630_UP
DrugEthionamide [536-33-4]; Up 200; 24uM; MCF7; HT_HG-U133A

DPF1 LTBP4 FBN1

4.73e-041971834418_UP
DrugPF-00539745-00 [351321-33-0]; Up 200; 10uM; PC3; HT_HG-U133A

LTBP4 THBS1 ASPSCR1

4.73e-041971835939_UP
DrugDiloxanide furoate [3736-81-0]; Up 200; 12.2uM; PC3; HT_HG-U133A

LRP2 LTBP4 NOTCH1

4.73e-041971836679_UP
DrugDiflorasone Diacetate [33564-31-7]; Up 200; 8uM; PC3; HT_HG-U133A

LTBP4 THBS1 ASPSCR1

4.73e-041971834077_UP
Drugestradiol, USP; Up 200; 0.01uM; PC3; HT_HG-U133A

LRP4 TNC ASPSCR1

4.73e-041971834465_UP
DrugNitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A

LRP2 LTBP4 THBS1

4.73e-041971836043_UP
DrugBisacodyl [603-50-9]; Up 200; 11uM; HL60; HT_HG-U133A

LRP2 TNC LTBP2

4.73e-041971832435_UP
DrugDisulfiram [97-77-8]; Down 200; 13.4uM; PC3; HT_HG-U133A

LRP2 TNC THBS1

4.80e-041981835729_DN
DrugSpiramycin [8025-81-8]; Up 200; 4.8uM; MCF7; HT_HG-U133A

LRP2 LTBP4 THBS1

4.80e-041981833419_UP
Drug(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Up 200; 12.2uM; PC3; HT_HG-U133A

DPF1 LRP1 THBS1

4.80e-041981835108_UP
DrugXylometazoline hydrochloride [1218-35-5]; Up 200; 14.2uM; PC3; HT_HG-U133A

LRP1 LRP4 NOTCH1

4.80e-041981832107_UP
DrugAG-013608 [351320-38-2]; Down 200; 10uM; MCF7; HT_HG-U133A

DPF1 MECOM FBN1

4.80e-041981836395_DN
DrugCyclacillin [3485-14-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

LRP2 LTBP4 THBS1

4.80e-041981834358_UP
DrugMeclocycline sulfosalicylate [73816-42-9]; Up 200; 5.8uM; PC3; HT_HG-U133A

LRP2 MECOM ASPSCR1

4.80e-041981836637_UP
DrugAtropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; PC3; HT_HG-U133A

LRP4 LTBP4 TNC

4.80e-041981835865_UP
DrugFoliosidine [2520-38-9]; Up 200; 13uM; PC3; HT_HG-U133A

LRP1 LTBP4 ASPSCR1

4.80e-041981833739_UP
DrugFlumequine [42835-25-6]; Up 200; 15.4uM; PC3; HT_HG-U133A

DPF1 LRP1 MECOM

4.80e-041981835104_UP
DrugPHA-00745360 [351320-33-7]; Up 200; 1uM; PC3; HT_HG-U133A

DPF1 LRP4 ASPSCR1

4.80e-041981834562_UP
Drugrotenone; Up 200; 1uM; PC3; HT_HG-U133A

IGFLR1 DPF1 TNC

4.80e-041981835948_UP
DrugSolanine alpha [20562-02-1]; Down 200; 4.6uM; PC3; HT_HG-U133A

LRP1 LRP2 LRP4

4.87e-041991834087_DN
DrugLidoflazine [3416-26-0]; Down 200; 8.2uM; PC3; HT_HG-U133A

LRP2 ASPSCR1 NOTCH1

4.87e-041991835804_DN
DrugBendroflumethiazide [73-48-3]; Up 200; 9.4uM; HL60; HT_HG-U133A

LRP2 MECOM LTBP2

4.87e-041991832555_UP
DrugMometasone furoate [83919-23-7]; Down 200; 7.6uM; MCF7; HT_HG-U133A

LRP2 MECOM THBS1

4.87e-041991835541_DN
DrugBephenium hydroxynaphthoate [3818-50-6]; Up 200; 9uM; MCF7; HT_HG-U133A

THBS1 ASPSCR1 LTBP2

4.87e-041991836466_UP
DrugMetaraminol bitartrate [33402-03-8]; Up 200; 8.6uM; MCF7; HT_HG-U133A

IGFLR1 DPF1 LTBP4

4.87e-041991834692_UP
DrugLabetalol hydrochloride [32780-64-6]; Up 200; 11uM; MCF7; HT_HG-U133A

DPF1 MECOM TNC

4.94e-042001833167_UP
Drugscopolamine

LRP1 LRP2 IKZF2

4.94e-04200183CID000005184
DrugIsometheptene mucate; Up 200; 8.2uM; HL60; HT_HG-U133A

TNC THBS1 LTBP2

4.94e-042001833145_UP
DrugCS-0398

LTBP4 LTBP2

5.48e-0444182CID005288149
DrugRp-8-Br-cGMPS

TNC THBS1

5.99e-0446182CID003035839
Drugtroglitazone

LRP1 LRP2 LRP4 ASPSCR1

6.66e-04526184CID000005591
DiseaseWeill-Marchesani syndrome

LTBP2 FBN1

1.05e-063182C0265313
DiseaseWeill-Marchesani Syndrome, Autosomal Dominant

LTBP2 FBN1

1.05e-063182C1869115
DiseaseWeill-Marchesani Syndrome, Autosomal Recessive

LTBP2 FBN1

1.05e-063182C1869114
DiseaseWeill-Marchesani syndrome

LTBP2 FBN1

2.11e-064182cv:C0265313
DiseaseWeill-Marchesani syndrome (is_implicated_in)

LTBP2 FBN1

2.11e-064182DOID:0050475 (is_implicated_in)
Diseaseaortic aneurysm

LRP1 FBN1

1.58e-0510182EFO_0001666
DiseaseMarfan Syndrome

LTBP2 FBN1

1.93e-0511182C0024796
DiseaseFEV/FEC ratio

LRP1 LTBP4 MECOM ASPSCR1 LTBP2 FBN1

6.19e-051228186EFO_0004713
Diseasevital capacity

LRP2 LTBP4 MECOM THBS1 ASPSCR1 LTBP2

6.42e-051236186EFO_0004312
DiseaseSplenomegaly

MECOM NOTCH1

8.06e-0522182C0038002
Diseaseurate measurement

LRP1 LRP2 LRP4 MECOM THBS1

1.57e-04895185EFO_0004531
Diseasespontaneous coronary artery dissection

LRP1 FBN1

1.62e-0431182EFO_0010820
Diseaseattempted suicide

DPF1 LRP2 FBN1

1.65e-04178183EFO_0004321
Diseasepack-years measurement, systolic blood pressure

LRP2 MECOM

1.95e-0434182EFO_0006335, EFO_0006526
Diseaseintraocular pressure measurement

LRP4 MECOM LTBP2 FBN1

2.21e-04509184EFO_0004695
Diseasecortical thickness

LRP1 LRP4 MECOM THBS1 FBN1

4.30e-041113185EFO_0004840
Diseaseaortic measurement

LRP1 LTBP4 FBN1

4.52e-04251183EFO_0020865
DiseaseChildhood Acute Lymphoblastic Leukemia

NOTCH1 IKZF2

4.58e-0452182C0023452
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

NOTCH1 FBN1

4.75e-0453182C4707243

Protein segments in the cluster

PeptideGeneStartEntry
LEDTCRRQDFNPCEY

ASPSCR1

36

Q9BZE9
NDDQLLFCDDCDRGY

DPF1

336

Q92782
DPDCEGHRCENGVYD

FAM193A

741

P78312
PDIHEERQYRCEDCD

MECOM

201

Q03112
SPCRNGGECRQSEDY

NOTCH1

836

P46531
ANDCGDYSDERDCPG

LRP1

2676

Q07954
RDCPDGADENDCQYP

LRP2

131

P98164
YNDCGDNSDERDCEM

LRP2

3781

P98164
RDPLECNICGYRSQD

IKZF2

496

Q9UKS7
RPSGYVCRQEGNECD

ADAM30

451

Q9UKF2
PNQDECLDNREGYCF

FBN1

2326

P35555
CPDYEFRENCGLNDH

IGFLR1

51

Q9H665
SQAYCTDDNECLRDP

LTBP2

881

Q14767
RECYFDTAAPDACDN

LTBP4

1181

Q8N2S1
DRDDVGDRCDNCPYN

THBS1

766

P07996
CVDCEAGSYRQNPDD

TAS1R3

521

Q7RTX0
YTGEDCRDRQCPRDC

TNC

491

P24821
GYADRRPCESNECGN

ZNF554

266

Q86TJ5
EEDEFPCQNGYCIRS

LRP4

111

O75096