Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionA-type (transient outward) potassium channel activity

KCND2 KCND3

1.49e-054322GO:0005250
GeneOntologyMolecularFunctionphosphotransferase activity, for other substituted phosphate groups

PGS1 PIGO

5.63e-0422322GO:0016780
GeneOntologyMolecularFunctionmonoatomic ion channel activity

OTOP3 CLCN2 PKD1L2 KCND2 KCND3

7.57e-04459325GO:0005216
GeneOntologyMolecularFunctionoutward rectifier potassium channel activity

KCND2 KCND3

8.52e-0427322GO:0015271
GeneOntologyMolecularFunctionchannel activity

OTOP3 CLCN2 PKD1L2 KCND2 KCND3

1.38e-03525325GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

OTOP3 CLCN2 PKD1L2 KCND2 KCND3

1.39e-03526325GO:0022803
GeneOntologyMolecularFunctionmonoatomic cation channel activity

OTOP3 PKD1L2 KCND2 KCND3

2.10e-03343324GO:0005261
GeneOntologyMolecularFunction4 iron, 4 sulfur cluster binding

RSAD1 NFU1

2.57e-0347322GO:0051539
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CLCN2 KCND2 KCND3

3.04e-03182323GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CLCN2 KCND2 KCND3

3.14e-03184323GO:0022832
GeneOntologyMolecularFunctiontransporter activity

PITPNM2 CNNM3 OTOP3 CLCN2 PKD1L2 KCND2 KCND3

3.71e-031289327GO:0005215
DomainDUF3399

KCND2 KCND3

8.52e-063322PF11879
DomainK_chnl_volt-dep_Kv4

KCND2 KCND3

8.52e-063322IPR003975
DomainShal-type

KCND2 KCND3

8.52e-063322PF11601
DomainShal-type_N

KCND2 KCND3

8.52e-063322IPR021645
DomainK_chnl_volt-dep_Kv4_C

KCND2 KCND3

8.52e-063322IPR024587
DomainPLD

PLD6 PGS1

5.94e-057322PS50035
DomainPLipase_D/transphosphatidylase

PLD6 PGS1

5.94e-057322IPR001736
DomainCBS_dom

CNNM3 CLCN2

5.30e-0420322IPR000644
DomainCBS

CNNM3 CLCN2

5.30e-0420322PF00571
DomainCBS

CNNM3 CLCN2

5.30e-0420322PS51371
DomainK_chnl_volt-dep_Kv

KCND2 KCND3

9.72e-0427322IPR003968
DomainVG_K_chnl

KCND2 KCND3

1.45e-0333322IPR028325
DomainBTB_2

KCND2 KCND3

3.71e-0353322PF02214
DomainT1-type_BTB

KCND2 KCND3

3.71e-0353322IPR003131
DomainChannel_four-helix_dom

KCND2 KCND3

4.28e-0357322IPR027359
Domain-

KCND2 KCND3

4.28e-03573221.20.120.350
PathwayREACTOME_PHASE_1_INACTIVATION_OF_FAST_NA_CHANNELS

KCND2 KCND3

5.80e-057242M27457
PathwayREACTOME_PHASE_1_INACTIVATION_OF_FAST_NA_CHANNELS

KCND2 KCND3

5.80e-057242MM15199
PathwayREACTOME_SYNTHESIS_OF_PG

PLD6 PGS1

7.73e-058242M26961
Pubmed

Kv4.3-Encoded Fast Transient Outward Current Is Presented in Kv4.2 Knockout Mouse Cardiomyocytes.

KCND2 KCND3

8.73e-07233226196737
Pubmed

Isolation and characterization of the human gene encoding Ito: further diversity by alternative mRNA splicing.

KCND2 KCND3

8.73e-0723329843794
Pubmed

Dendritic Kv4.2 potassium channels selectively mediate spatial pattern separation in the dentate gyrus.

KCND2 KCND3

8.73e-07233234386734
Pubmed

Genomic organisation and chromosomal localisation of two members of the KCND ion channel family, KCND2 and KCND3.

KCND2 KCND3

8.73e-07233210942109
Pubmed

Differential expression of I(A) channel subunits Kv4.2 and Kv4.3 in mouse visual cortical neurons and synapses.

KCND2 KCND3

8.73e-07233217122053
Pubmed

Mutations in the genes KCND2 and KCND3 encoding the ion channels Kv4.2 and Kv4.3, conducting the cardiac fast transient outward current (ITO,f), are not a frequent cause of long QT syndrome.

KCND2 KCND3

8.73e-07233215563876
Pubmed

I(A) channels encoded by Kv1.4 and Kv4.2 regulate neuronal firing in the suprachiasmatic nucleus and circadian rhythms in locomotor activity.

KCND2 KCND3

2.62e-06333222815518
Pubmed

Unique clustering of A-type potassium channels on different cell types of the main olfactory bulb.

KCND2 KCND3

2.62e-06333218371079
Pubmed

Molecular dissection of I(A) in cortical pyramidal neurons reveals three distinct components encoded by Kv4.2, Kv4.3, and Kv1.4 alpha-subunits.

KCND2 KCND3

2.62e-06333220371829
Pubmed

Role of heteromultimers in the generation of myocardial transient outward K+ currents.

KCND2 KCND3

2.62e-06333211909823
Pubmed

A-type K+ channels encoded by Kv4.2, Kv4.3 and Kv1.4 differentially regulate intrinsic excitability of cortical pyramidal neurons.

KCND2 KCND3

2.62e-06333222615428
Pubmed

Gene structures and expression profiles of three human KCND (Kv4) potassium channels mediating A-type currents I(TO) and I(SA).

KCND2 KCND3

2.62e-06333210729221
Pubmed

Toll-like receptor 3 controls QT interval on the electrocardiogram by targeting the degradation of Kv4.2/4.3 channels in the endoplasmic reticulum.

KCND2 KCND3

2.62e-06333230758987
Pubmed

Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1.

KCND2 KCND3

5.23e-06433214980207
Pubmed

Parvalbumin+ Neurons and Npas1+ Neurons Are Distinct Neuron Classes in the Mouse External Globus Pallidus.

KCND2 KCND3

5.23e-06433226311767
Pubmed

Accessory Kvbeta1 subunits differentially modulate the functional expression of voltage-gated K+ channels in mouse ventricular myocytes.

KCND2 KCND3

5.23e-06433215662035
Pubmed

IA Channels Encoded by Kv1.4 and Kv4.2 Regulate Circadian Period of PER2 Expression in the Suprachiasmatic Nucleus.

KCND2 KCND3

5.23e-06433226152125
Pubmed

Ion channel expression in the developing enteric nervous system.

CLCN2 KCND2 KCND3

5.92e-063733325798587
Pubmed

Kv4 potassium channels form a tripartite complex with the anchoring protein SAP97 and CaMKII in cardiac myocytes.

KCND2 KCND3

8.72e-06533219213956
Pubmed

The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient.

KCND2 KCND3

8.72e-06533216239150
Pubmed

Interdependent roles for accessory KChIP2, KChIP3, and KChIP4 subunits in the generation of Kv4-encoded IA channels in cortical pyramidal neurons.

KCND2 KCND3

1.31e-05633220943905
Pubmed

Targeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f).

KCND2 KCND3

1.31e-05633218603586
Pubmed

Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model.

KCND2 KCND3

1.83e-05733228646025
Pubmed

Functional suppression of Kcnq1 leads to early sodium channel remodelling and cardiac conduction system dysmorphogenesis.

KCND2 KCND3

7.89e-051433223542581
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

NIPSNAP2 PLD6 PGS1 RSAD1 MICU2 NFU1 COQ9

7.90e-05113633734800366
Pubmed

Neuronal interleukin-16 (NIL-16): a dual function PDZ domain protein.

KCND2 KCND3

9.10e-051533210479680
Pubmed

Genetic determinants of P wave duration and PR segment.

MICU2 KCND3

1.18e-041733224850809
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

NIPSNAP2 PGS1 RSAD1 MICU2 NFU1 COQ9

2.10e-0492633620877624
Pubmed

Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer.

CNNM3 GGTLC1

2.18e-042333220932654
Pubmed

Brugada Syndrome

KCND2 KCND3

2.38e-042433220301690
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CLCN2 KCND2 KCND3

3.12e-0413933316985003
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

NIPSNAP2 PGS1 RSAD1 MICU2 NFU1 COQ9

4.05e-04104733618614015
Pubmed

LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation.

KCND2 KCND3

4.81e-043433226378152
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

IQCN PKD1L2 ALDH16A1

5.43e-0416833330631154
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

PITPNM2 NIPSNAP2 CAMSAP1 KCND2 KCND3 FAM120C

6.32e-04113933636417873
Pubmed

International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.

KCND2 KCND3

6.66e-044033216382104
Pubmed

Defining the membrane proteome of NK cells.

CNNM3 APOBR PARP16 PIGO ALDH16A1 GZMM

7.21e-04116833619946888
Pubmed

A germline-specific class of small RNAs binds mammalian Piwi proteins.

PGS1 TBL2 PIGO ALDH16A1

8.41e-0445033416751776
Pubmed

Identification of G protein-coupled receptor genes from the human genome sequence.

S1PR5 PIGO

8.80e-044633212044878
InteractionSCN4A interactions

S1PR5 PLD6 PARP16 PIGO

1.93e-0598334int:SCN4A
GeneFamilyPotassium voltage-gated channels

KCND2 KCND3

8.84e-0440202274
CoexpressionGSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_ATOPIC_PATIENT_DN

KDM3B PITPNM2 PGS1 CLCN2 PIGO

4.91e-06200335M7075
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CNNM3 CLCN2 KCND3

1.74e-041473332d9044ddf01b6838a44a4518b442d7e7cb0bf910
ToppCellPBMC-Control-cDC_8|Control / Compartment, Disease Groups and Clusters

CLCN2 PARP16 TTLL11

1.95e-04153333db1a6914f2033fb0748e0523cffe5d6dc4e901be
ToppCellIIH-CD8-exh_CD4|IIH / Condition, Cell_class and T cell subcluster

CNNM3 PLD6 PGS1

1.99e-04154333a2f51a3c5455fe2483e438375ea856afce8262fe
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|Myeloid_cells / Location, Cell class and cell subclass

PLD6 IQCN GZMM

2.61e-04169333bea8aba1f3cc3d0e8d448c1c45f5354d26ebf850
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-MAIT_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

S1PR5 PGS1 GZMM

2.66e-04170333059f7ae615342ea19f43b0a405cd7272251a78a9
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-mature_NK_T_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

S1PR5 PPM1N GZMM

2.71e-04171333a0462781d22c391b3c6c8a72586c385ac089ca5d
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l4|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

S1PR5 PPM1N GZMM

2.71e-0417133385b655dc8a3cbf0e8097e951116490e326a795ac
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

S1PR5 PPM1N GZMM

2.71e-04171333f12c2e48637b96557afbc2006a3a23ba21b7951e
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

S1PR5 PPM1N GZMM

2.71e-0417133312c98dea7370377695c5d22309f78ba03e282a0e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SH2B3 APOBR KCND3

2.80e-0417333373f858f2c45d19b9ec8d99ac02c91551790f670c
ToppCell18-Airway-Immune-Hematopoietic,_Natural_Killer_Cell|Airway / Age, Tissue, Lineage and Cell class

S1PR5 APOBR GZMM

2.80e-04173333054cb468a2a10a96aa1d971618993f6777569e14
ToppCelldroplet-Liver-Npc-18m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKD1L2 FAM120C PPM1N

2.80e-041733339ba55e21d1037ec3150d77895e52f0b051df65da
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|368C / Donor, Lineage, Cell class and subclass (all cells)

S1PR5 CLCN2 GZMM

3.35e-04184333d48807f9da48bdd015a54c606d2e2a311f181396
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SH2B3 APOBR KCND3

3.35e-041843334f4aeef3b821a003e857fe4a195124d44b2d7479
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

S1PR5 PPM1N GZMM

3.41e-041853330382bfbc96c23403b18fe439d8070ea9a7d29fd2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

S1PR5 PPM1N GZMM

3.46e-04186333facc1bd8920003ad03d1893c32fc606d82b4d50a
ToppCell390C-Lymphocytic-NK_cells-NK_cell_C|390C / Donor, Lineage, Cell class and subclass (all cells)

S1PR5 APOBR GZMM

3.52e-041873331e8651e6c547384ace5a66b96c6b24a7f390a7ee
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

S1PR5 MICU2 GZMM

3.52e-041873338c69fd469df2915c56ede534cee3ef23d5f64ebf
ToppCelldroplet-Limb_Muscle-nan-3m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNNM3 APOBR GZMM

3.63e-0418933316a4c92dd7a0d60f3691bd3130a091a9a54730f1
ToppCell15-Distal-Immune-Hematopoietic,_Natural_Killer_Cell|Distal / Age, Tissue, Lineage and Cell class

S1PR5 APOBR GZMM

3.63e-04189333281a7ccb18edf542a7756f2f90b20594436097f9
ToppCellwk_08-11-Hematologic_Lymphocytic-NK|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

S1PR5 APOBR GZMM

3.68e-0419033386b0d142b7d1a3b35580edd104f947106be2c9c6
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

S1PR5 PPM1N GZMM

3.68e-04190333600b9674197f743dea1d19d3df0fc993b6e6aa25
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

S1PR5 PPM1N GZMM

3.80e-04192333c5f77c2103841505d13e09173549811312ef2f01
ToppCellIPF-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

PITPNM2 IQCN PPM1N

3.80e-04192333356e7a820b744a0ac87352a8d0e6e8d9fa9ed7d2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

S1PR5 PPM1N GZMM

3.80e-04192333e981162f387a31111c0ae8355dbe9db5785c4838
ToppCell18-Distal-Immune-Hematopoietic,_Natural_Killer_Cell|Distal / Age, Tissue, Lineage and Cell class

S1PR5 APOBR GZMM

3.80e-04192333dd47d47d0a7219771b275c4cf5f2b768424216c8
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

S1PR5 PPM1N GZMM

3.80e-0419233397c312c82ec025c13052f8d424b11c0034c8ea54
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

S1PR5 PPM1N GZMM

3.80e-041923333b0a52e4e77ae4539a034dcb419773b8e2aa5d51
ToppCellMild_COVID-19-T/NK-NK|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

PITPNM2 S1PR5 GZMM

3.86e-041933339c455d9d845fa230e9a61d9a5f9d6a2ccf5d7350
ToppCellbackground-NK_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

S1PR5 APOBR GZMM

3.86e-04193333f8d6eff1e04926f85d265ec39fe66897fe29574d
ToppCellT_cells-CD56_dim_CD16+_NK_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

PITPNM2 S1PR5 APOBR

3.92e-04194333335c6c2f3f319d4f19eace62f8826a0f40c130f6
ToppCelllymphoid-NK_cell-NK_cell|lymphoid / Lineage, cell class and subclass

S1PR5 APOBR GZMM

4.03e-041963335e6238fe131e349013c60a73c99f84a6be7955ef
ToppCellBL-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PITPNM2 S1PR5 GZMM

4.03e-04196333cfbeaabbeeb197f0cf8240a752d1f2995d59d7b7
ToppCelllymphoid-NK_cell|lymphoid / Lineage, cell class and subclass

S1PR5 APOBR GZMM

4.03e-041963330c7fb03ef782256f61624afc5c1bfaed9f1005fb
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

S1PR5 TTLL11 GZMM

4.09e-0419733352246d1354c4e2b13d48c878643edf843d2b50d2
ToppCellbackground-NK_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

S1PR5 APOBR GZMM

4.09e-04197333e8e1d3e557fe821efe81012e759e35e4ae33ce86
ToppCellControl_saline-Hematopoietic_Lymphocytic-Lymphocytic_NK/T|Control_saline / Treatment groups by lineage, cell group, cell type

S1PR5 APOBR GZMM

4.16e-041983339663cf0c8296d3a7b0329cb725ccceeea7849cbc
ToppCellLPS_only-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT|LPS_only / Treatment groups by lineage, cell group, cell type

S1PR5 APOBR GZMM

4.22e-04199333b62a756b5472972156d05051a58671a58bef1f16
ToppCellLPS_IL1RA_TNF-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

S1PR5 APOBR GZMM

4.22e-04199333c23a53a20487a8abfeb91fa5fc9c06823dd657e9
ToppCellControl-NK|Control / Disease condition and Cell class

S1PR5 APOBR GZMM

4.22e-04199333f3316fb97c6065286ffd22a0ad9fe7aa5b3b5650
ToppCellControl_saline-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT|Control_saline / Treatment groups by lineage, cell group, cell type

S1PR5 APOBR GZMM

4.22e-041993332d7ebb9642f6fe0afd5e3fdc711ded54b73acd11
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-CD4+_CTL|Leuk-UTI / Disease, condition lineage and cell class

S1PR5 KCND3 GZMM

4.22e-04199333b2609f9d716fdd04f35f0da7f8995d28d7df431d
ToppCellMS-IIF-Lymphocyte-T/NK-CD4+_CTL|IIF / Disease, condition lineage and cell class

S1PR5 TTLL11 GZMM

4.22e-04199333232f85175f49322eee903dd5e7d8e5a94c751ee0
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IQCN CAMSAP1 SH2B3

4.28e-0420033388d713dfc792e7609bf7ecfb28f87cb748088570
ToppCellBronchial-NucSeq-Immune_Lymphocytic-NK-ILC|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

S1PR5 APOBR GZMM

4.28e-0420033356d738ff019682af7f1f8cbe7b262a75dc8596d5
ToppCellBronchial-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

S1PR5 APOBR GZMM

4.28e-042003337eed3d932018d6a87ce37d013883b371db55caeb
ToppCellBronchial-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

S1PR5 APOBR GZMM

4.28e-042003330f8e2fed93cc103b20a825d8d3e83787c5c015cc
ToppCell356C-Lymphocytic-ILC-ILC-3|ILC / Donor, Lineage, Cell class and subclass (all cells)

S1PR5 GZMM

9.29e-0461332d0b33a48ee2faf68b270f9279c630437f3e8b20b
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(Neuron.Gad1Gad2.Pvalb-Unc5b)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PLD6 GZMM

1.55e-0379332cc17a013a4a57a99c404b10449ef61ce559631d1
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(Neuron.Gad1Gad2.Pvalb-Unc5b)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PLD6 GZMM

1.55e-037933219fb2bc964589ea40e7b9f0809c641331c93dacd
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Sc17a7.Calb1-Lpl-Penk_(Layer_2/3)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

OTOP3 PPM1N

1.71e-0383332b683c8496474b0df0042f596c9b0ea5916a2ab15
ToppCellSevere-CD8+_T|Severe / Disease group and Cell class

S1PR5 GZMM

2.14e-0393332433d23253b2102cf65df338a488554e5ab409d7e
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8-MAIT|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KCND3 GZMM

3.03e-0311133258a1536cf63568ffc985baefa495af659dd9ba88
ToppCell(05)_Ciliated-(3)_72hpi|(05)_Ciliated / shred by cell type and Timepoint

PLD6 PARP16

3.14e-03113332eaa5bc8f8183b353ee1e7618e99220eb3684cd60
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l14|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KDM3B S1PR5

3.30e-03116332f2bf9599040f43b5ea8724841d7b71c0a859c016
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

FJX1 SH2B3

3.30e-03116332f32f7eddfe33adb3b5cf7c34667a481a305c5163
ToppCellMyeloid-Myeloid-C_(Cd16+_Monocyte)|Myeloid / shred on cell class and cell subclass (v4)

S1PR5 CLCN2

3.36e-03117332d1936e76a935216783a73ab414e4147fa48e68eb
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OTOP3 PPM1N

3.41e-031183328d96a4879b28979fa04fbaeffa271a6b9ecbe867
ToppCellMyeloid-C_(Cd16+_Monocyte)|World / shred on cell class and cell subclass (v4)

S1PR5 APOBR

3.82e-03125332c73a77340e79f73fd1f900724e82a94d82e6b1bf
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Calb1_(Superficial_layer_pyramidal_cells--Layer_2/3)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

OTOP3 PKD1L2

3.88e-031263327dcc79bf35482e8e5e5a1de7279ba080edb70522
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-B_lymphocytic-plasmablast|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MSANTD2 CAMSAP1

4.00e-031283323c810fc4934dee4de2b8b64a2e152547b08c6f8d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

S1PR5 GZMM

4.06e-03129332e6dff5bc93dd946f9296ce162ce8cf0f898d2d8e
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PITPNM2 FAM120C

4.13e-03130332fc68a648161dd314d9ee6612fd039cb12171b8c6
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PITPNM2 FAM120C

4.13e-031303320f9d3e6297f48ae14d24ac997d8d3a94f337d4d4
ToppCellLymphoid-NK_cells|World / shred on cell class and cell subclass (v4)

OTOP3 APOBR

4.19e-03131332b0b62392d1637601115e85f5584fdcd5dbd0c778
ToppCellPBMC-Mild-cDC_4|Mild / Compartment, Disease Groups and Clusters

FAM120C GZMM

4.31e-03133332e53fbd69775a4bff61de82557342f7ac80915c4d
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells-iNKT-MAIT|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

S1PR5 GZMM

4.38e-0313433292981dc68c1b3cdc53f9cf83386c47f0c6c98ae7
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

S1PR5 CAMSAP1

4.44e-03135332c4d3c9eba2a85ac40fea5ecfcc2b442a472323d0
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

S1PR5 GZMM

4.63e-03138332321070b6900887b27da0f2b25808a05a8ab89ee7
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

S1PR5 GZMM

4.63e-0313833219ffd66256fa94d728138d37d0a5a3bac7722dbb
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-iNKT-MAIT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

S1PR5 GZMM

4.77e-03140332a8f3b01d03ee0bf0e752327a98d6b9035930c2b0
ToppCellMild/Remission-B_naive-5|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

IQCN GZMM

4.90e-03142332fc5fc2d2b4b976358b8ce762c1f440b20db84103
ToppCellBac-SEP-Lymphocyte-T_NK-CD8_Naive|Bac-SEP / Disease, Lineage and Cell Type

KCND3 GZMM

5.03e-03144332fdcf84e8b5fdc0730f243919f9cc30492e24dd75
ToppCellBLOOD--(0)_NK_cell-(0)_NK_cells_(CD56dim-like)|(0)_NK_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

S1PR5 GZMM

5.10e-031453326dd81d53d006fcc206a10969374a11c372f92133
ToppCell368C-Lymphocytic-NK_cells-NK_cell_A|368C / Donor, Lineage, Cell class and subclass (all cells)

S1PR5 GZMM

5.17e-031463320e38e1fa40b1fcd1bb61f7af7cc2206846c192ae
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CAMSAP1 PIGO

5.24e-03147332ad0c575bc9c5f201f2a7810452e8b3f741e65d89
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

S1PR5 GZMM

5.24e-0314733255f4b3289094a1eab6d7a6c8f214ec7b031edfa8
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|368C / Donor, Lineage, Cell class and subclass (all cells)

S1PR5 GZMM

5.24e-031473323ed5b020ce1f1277917d79ef1f7da53fa474e8db
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|368C / Donor, Lineage, Cell class and subclass (all cells)

S1PR5 GZMM

5.24e-03147332743767abdb3b5ecad870b617f515b037ce280818
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

S1PR5 GZMM

5.24e-0314733222c9605869dd2e789896cd2790ee8def2605de57
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CAMSAP1 PIGO

5.24e-03147332f5109e0f4e8b46a977a763c9c72a2df9840e3977
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

S1PR5 GZMM

5.24e-03147332ac272595818d25c6b84b107555b3351e912a01a7
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

S1PR5 APOBR

5.31e-031483323aa47398cb805c6c6e16b375cc3e9c7f04bb91f4
ToppCellLymphoid-Lymphoid-NK_cells|Lymphoid / shred on cell class and cell subclass (v4)

OTOP3 APOBR

5.31e-03148332d51a4b654a88d58dcdf29c2bc362c0cc1c40723a
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RSAD1 GZMM

5.38e-031493323378d0fe79de6d7879fd48717ded5027593c785f
ToppCell356C-Lymphocytic-NK_cells-NK_cell_C|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

S1PR5 GZMM

5.38e-0314933295b21d67d6c335330a508f78d5cc074fdaf92275
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

S1PR5 APOBR

5.45e-0315033234774b015adecc2be56a471fda8994e89a6ad93e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related|GW10 / Sample Type, Dataset, Time_group, and Cell type.

FAM120C ALDH16A1

5.52e-03151332edb2f59789c295838d2030b80c792cbea25eaa3d
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related-Oligodendrocyte/OPC|GW10 / Sample Type, Dataset, Time_group, and Cell type.

FAM120C ALDH16A1

5.52e-031513324533bccc996395f74b16af939ce79b6fe253c073
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell|368C / Donor, Lineage, Cell class and subclass (all cells)

S1PR5 GZMM

5.52e-03151332512f7f37ddc8dfa1906f7fff92b571929236c9ea
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

S1PR5 APOBR

5.59e-03152332ed6df77ba04b715e12c2e1591b4a1e894ca49d25
ToppCell356C-Lymphocytic-NK_cells-NK_cell_B2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

S1PR5 GZMM

5.66e-0315333282a96ca1912858c4311b87b3b0ba5a0a41e564b5
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

APOBR PIGO

5.66e-031533324eb9c2d7e4b95d44198fc87dc115a08ef0153e26
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

APOBR PIGO

5.66e-0315333226b5b45c117d155b028d298a0b93e16d343dca97
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

S1PR5 GZMM

5.66e-03153332d8773ee16c7d3e0834b9f64054d42336d6f9833b
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

APOBR PIGO

5.66e-031533320f12e38f2cbf69a520764289b0aa4dedc645f714
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|356C / Donor, Lineage, Cell class and subclass (all cells)

S1PR5 GZMM

5.66e-031533325fb7d92cddc816c64071465e955ed0ea3bb45316
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|367C / Donor, Lineage, Cell class and subclass (all cells)

S1PR5 GZMM

5.73e-03154332a39877cdf7b441b5c953f744ed30f1d5acf4ea19
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B|343B / Donor, Lineage, Cell class and subclass (all cells)

S1PR5 GZMM

5.73e-03154332886e7cd01cb48ca3e97debeea2b1f100b09d47e6
ToppCellfacs-Spleen-nan-24m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

S1PR5 COQ9

5.73e-03154332bd283c2367afb99294e7576a0c0167eb7c69ad6b
ComputationalNeighborhood of PRKAG1

KDM3B NIPSNAP2 TBL2 COQ9

5.56e-04224194MORF_PRKAG1
ComputationalNeighborhood of MATK

S1PR5 GZMM

7.98e-0424192GNF2_MATK
DiseaseSudden Cardiac Arrest

KCND2 KCND3

2.98e-058312C1720824
Diseasecalcium measurement

PITPNM2 CNNM3 SH2B3 FAM120C NFU1

4.62e-04628315EFO_0004838
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

PITPNM2 PGS1 SH2B3

1.62e-03222313EFO_0008317, EFO_0020943
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

PITPNM2 PGS1 SH2B3

2.64e-03264313EFO_0008317, EFO_0020944
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

PGS1 SH2B3

5.15e-03102312EFO_0004329, EFO_0004611

Protein segments in the cluster

PeptideGeneStartEntry
AAVEAARMAFKGWSA

ALDH16A1

81

Q8IZ83
RQVVAAGTRCSMAGW

GZMM

136

P51124
MVDASGRAAAEGWRK

CAMSAP1

1

Q5T5Y3
AAAAAAAACRGMSWT

MSANTD2

91

Q6P1R3
MAARVLRARGAAWAG

NIPSNAP2

1

O75323
AGVMSDRSWFQDGRA

IQCN

1011

Q9H0B3
MGRGARAAAAQSRWG

OTOP3

1

Q7RTS5
MAAGVAAWLPFARAA

KCND3

1

Q9UK17
MAATARRGWGAAAVA

NFU1

1

Q9UMS0
MAVAAAAAAGPVFWR

PGS1

1

Q32NB8
QAIVRMAGGWAAASD

GGTLC1

201

Q9BX51
RFGASAAQGWRARME

PPM1N

66

Q8N819
AWRAGTVRAMSGAVP

KDM3B

46

Q7LBC6
MAAGVAAWLPFARAA

KCND2

1

Q9NZV8
FARAAAIGWMPVASG

KCND2

11

Q9NZV8
GQRSMSVAAGCWGRA

PITPNM2

1321

Q9BZ72
TAALRRAWGDISGFM

PKD1L2

2301

Q7Z442
MQPSGWAAAREAAGR

PARP16

1

Q8N5Y8
WAAAREAAGRDMLAA

PARP16

6

Q8N5Y8
AAAWLEAARGARMVA

FJX1

141

Q86VR8
VGAPAWREAAQAMAR

CCDC105

16

Q8IYK2
AGMVVGQWAGSRSSR

FAM120C

961

Q9NX05
MAAAAVSGALGRAGW

COQ9

1

O75208
DWGAMDAKAGSLRRV

CRYGC

156

P07315
SSRGRTLAMAAAAWG

S1PR5

146

Q9H228
MGRLSWQVAAAAAVG

PLD6

1

Q8N2A8
MALPGARARGWAAAA

RSAD1

1

Q9HA92
MAAAAGSCARVAAWG

MICU2

1

Q8IYU8
MARNWASSGAASGRK

PRDM7

391

Q9NQW5
AMGSARGGAANSWSE

APOBR

971

Q0VD83
GAAFGRLVGESMAAW

CLCN2

466

P51788
MAAAVAAAGRLGWLF

CNNM3

1

Q8NE01
MAAAASVTGRVTWAA

TTLL11

1

Q8NHH1
ADEASMDSGARWQRG

SH2B3

206

Q9UQQ2
ESWARFSLVRMAGGT

PIGO

441

Q8TEQ8
LMATAAVARGWLRAG

TBL2

21

Q9Y4P3