Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioninsulin-like growth factor binding

IGF2R IGFBP2 LRP2

8.42e-0519913GO:0005520
DomainTIL_dom

LRP2 MUC5B OTOG

3.79e-0514903IPR002919
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

KPNA4 PITHD1 DCHS2 COPB1 LRP2 CCAR1 ZNF343 PSMD1 SMARCAD1 VPS54 STAMBPL1 TBC1D23 TF B4GALT3

6.18e-061285911435914814
Pubmed

Development of IGF signaling antibody arrays for the identification of hepatocellular carcinoma biomarkers.

IGF2R IGFBP2

6.77e-06291223071652
Pubmed

[The expression of hepatocyte growth factor and heparanase in laryngeal squamous cell carcinoma and its clinical significance].

HGF HPSE

6.77e-06291219452723
Pubmed

Heparanase plays a dual role in driving hepatocyte growth factor (HGF) signaling by enhancing HGF expression and activity.

HGF HPSE

6.77e-06291221131364
Pubmed

Characterization of palladin, a novel protein localized to stress fibers and cell adhesions.

ACTN2 PALLD

6.77e-06291210931874
Pubmed

Downregulation of CD147 induces malignant melanoma cell apoptosis via the regulation of IGFBP2 expression.

IGFBP2 BSG

6.77e-06291230272281
Pubmed

Insulin-like growth factor-II and its binding proteins in placental development.

IGF2R IGFBP2

2.03e-0539121380437
Pubmed

IGF-I and IGFBP-2 Stimulate AMPK Activation and Autophagy, Which Are Required for Osteoblast Differentiation.

IGFBP2 PRKAA1

2.03e-05391226556533
Pubmed

An essential role of N-terminal arginylation in cardiovascular development.

UBR1 ATE1

4.05e-05491212098698
Pubmed

The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments.

UBR1 ATE1

4.05e-05491222670058
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PLCD3 UBR1 PKP4 PRKAA1 CCAR1 SMARCAD1 TASOR PALLD EXOC8

5.28e-0565091938777146
Pubmed

Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis.

LHX2 SMARCAD1

6.74e-0559128872459
Pubmed

Insulin-like growth factors and related proteins in plasma and cerebrospinal fluids of HIV-positive individuals.

IGF2R IGFBP2

6.74e-05591225890304
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KPNA4 SCN11A SMARCA5 PCDHGB1 PCDHGA12 BSG SNX25 LMLN CCAR1 PSMD1 ACTN2 POTEJ TASOR

9.59e-051442911335575683
Pubmed

Altered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathway.

UBR1 ATE1

1.01e-04691210805755
Pubmed

Insulin-like growth factor binding proteins in the human adrenal gland.

IGF2R IGFBP2

1.01e-0469127511544
Pubmed

Five enzymes of the Arg/N-degron pathway form a targeting complex: The concept of superchanneling.

UBR1 ATE1

1.01e-04691232366662
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

KPNA4 ARHGAP32 KLHL24 SMARCAD1 ZMYM1 ADNP MAP3K1

1.39e-0443091735044719
Pubmed

The N-terminal cysteine is a dual sensor of oxygen and oxidative stress.

UBR1 ATE1

1.41e-04791234893540
Pubmed

Transferrin is an insulin-like growth factor-binding protein-3 binding protein.

IGFBP2 TF

1.41e-04791211297622
Pubmed

Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies.

ACTN2 PALLD

1.88e-04891211309420
Pubmed

An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse.

SMARCA5 TASOR

1.88e-04891215890782
Pubmed

A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: insights from genetic analyses of the protocadherin-gamma gene cluster.

LHX2 PCDHGB1 PCDHGA12

2.12e-044491319029045
Pubmed

Expression of IGF ligand and receptor genes during preimplantation mammalian development.

IGF2R IGFBP2

2.41e-0499128398121
Pubmed

New insights on the functional role of URG7 in the cellular response to ER stress.

COPB1 PSMD1 ADNP

2.58e-044791329704455
Pubmed

A protein interaction landscape of breast cancer.

KPNA4 IGF2R PKP4 MUC5B SMARCAD1 ZMYM1 RGL2 CDK6

2.63e-0463491834591612
Pubmed

Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk.

LZTR1 MAP3K1

3.01e-041091237592023
Pubmed

N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis.

ATE1 PADI1

3.01e-041091229507222
Pubmed

Human transcription factor protein interaction networks.

LHX2 ARHGAP32 SMARCA5 COPB1 BSG EPC1 LRP2 CCAR1 COP1 PSMD1 ZMYM1 ADNP

3.48e-041429911235140242
Pubmed

IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes.

IGF2R IGFBP2

3.67e-041191215721138
Pubmed

Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis.

IGF2R IGFBP2

3.67e-04119127750499
Pubmed

A dual-color FISH gene map of the proximal region of rat Chromosome 4 and comparative analysis in human and mouse.

HGF CDK6

3.67e-041191211707776
Pubmed

Lhx2 is expressed in the septum transversum mesenchyme that becomes an integral part of the liver and the formation of these cells is independent of functional Lhx2.

HGF LHX2

3.67e-041191215261829
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

ARHGAP32 UACA PLXND1 TASOR

3.87e-0413091412421765
Pubmed

CHD4 and the NuRD complex directly control cardiac sarcomere formation.

ACTN2 TNNI2

4.39e-041291229891665
Pubmed

Dual role for LIM-homeodomain gene Lhx2 in the formation of the lateral olfactory tract.

LHX2 TFAP2E

4.39e-041291217329426
Pubmed

Genetic dissection of the glutamatergic neuron system in cerebral cortex.

LHX2 PLXND1

5.18e-041391234616069
Pubmed

Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis.

IGF2R IGFBP2

5.18e-041391235741102
Pubmed

Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis.

HGF LHX2

5.18e-041391236198802
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

PITHD1 ARHGAP32 IGF2R COPB1 BSG PSMD1 ATE1 PALLD

5.46e-0470891839231216
Pubmed

Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo.

LHX2 PLXND1

6.04e-041491231475747
Pubmed

Direct and indirect neurogenesis generate a mosaic of distinct glutamatergic projection neuron types in cerebral cortex.

LHX2 PLXND1

6.95e-041591237348506
Pubmed

Maturation of postnatally generated olfactory bulb granule cells depends on functional γ-protocadherin expression.

PCDHGB1 PCDHGA12

6.95e-041591223515096
Pubmed

Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.

FRMD4A PKP4 PSMD1

7.35e-046791329254152
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

FRMD4A ARHGAP32 LZTR1 IGF2R UACA BSG PKP4

7.48e-0456991730639242
Pubmed

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

FRMD4A EPC1 CCAR1 STAMBPL1 ATE1 IFIT3

7.90e-0441591616385451
Pubmed

Differential regulation of NF-κB-mediated proviral and antiviral host gene expression by primate lentiviral Nef and Vpu proteins.

HGF IGFBP2

7.93e-041691225620704
Pubmed

Functions of c-Jun in liver and heart development.

HGF TF

7.93e-041691210352021
Pubmed

Mouse development and cell proliferation in the absence of D-cyclins.

CCNF CDK6

7.93e-041691215315760
Pubmed

Genome-wide association of body fat distribution in African ancestry populations suggests new loci.

LHX2 MAP3K1

7.93e-041691223966867
Pubmed

ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons.

ACVR1B HPSE

7.93e-041691231676717
Pubmed

Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers.

ACTN2 PALLD

7.93e-041691225987543
Pubmed

GRP94 is essential for mesoderm induction and muscle development because it regulates insulin-like growth factor secretion.

IGF2R TF

8.98e-041791217634284
Pubmed

Target gene analysis by microarrays and chromatin immunoprecipitation identifies HEY proteins as highly redundant bHLH repressors.

PLXND1 TIPARP

8.98e-041791222615585
Pubmed

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

IGF2R BSG GIT2 TNS1 PALLD

9.34e-0428591521423176
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ARHGAP32 IGF2R UACA SPHKAP PKP4 CCAR1 GIT2 ADNP TNS1

9.51e-0496391928671696
Pubmed

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.

COPB1 BSG PSMD1 TF

9.69e-0416691435687106
Pubmed

Architectural niche organization by LHX2 is linked to hair follicle stem cell function.

LHX2 PALLD

1.01e-031891224012369
Pubmed

Deciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis.

TNNI2 MAP3K1

1.12e-031991223201579
Pubmed

SHARPIN negatively associates with TRAF2-mediated NFκB activation.

SCN11A PSMD1

1.12e-031991221829440
Pubmed

Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study.

COPB1 RNF43

1.12e-031991225208829
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ZNF16 ZNF765 IGF2R COPB1 BSG RRN3 PSMD1 ZMYM1 TBC1D23 EXOC8

1.20e-031203911029180619
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

KLHL24 IGF2R BSG RRN3 RPTN PSMD1 STAMBPL1 ATE1 EXOC8

1.28e-03100591919615732
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

LZTR1 IGF2R BSG PKP4 CCAR1 PSMD1 VPS54 TBC1D23 PALLD

1.30e-03100791934597346
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

ARHGAP32 PKP4 CCAR1 TASOR

1.31e-0318091435198878
Pubmed

Temporal and spatial transcriptional programs in murine kidney development.

OGFR SMOC2

1.38e-032191215998744
Pubmed

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.

GBP4 IFIT3

1.38e-032191219158679
Pubmed

Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome.

UBR1 COPB1 ATE1

1.42e-038491331616248
Pubmed

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

LZTR1 IGF2R UACA BSG PKP4 VPS54

1.45e-0346791630194290
Pubmed

Characterization of 458 single nucleotide polymorphisms of disease candidate genes in the Korean population.

LRP2 MUC5B

1.51e-032291212768436
Pubmed

A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.

KLHL24 LZTR1 GIT2

1.57e-038791337495603
Pubmed

Illuminating the terminal nerve: Uncovering the link between GnRH-1 neuron and olfactory development.

LHX2 TFAP2E

1.80e-032491238488687
Pubmed

The sperm-associated antigen 6 interactome and its role in spermatogenesis.

COPB1 SNX25 PKP4 IFIT3

1.89e-0319991431146259
Pubmed

Proteomic analysis of the 20S proteasome (PSMA3)-interacting proteins reveals a functional link between the proteasome and mRNA metabolism.

PSMD1 ACTN2 TF

1.90e-039391322079093
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

UBR1 SMARCA5 COPB1 OGFR PSMD1 PALLD

1.92e-0349491626831064
Pubmed

Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span.

IGF2R IGFBP2

1.95e-032591223563309
Pubmed

Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation.

IGF2R IGFBP2

2.11e-032691227861515
Pubmed

Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis.

THBS2 IGFBP2

2.11e-032691226244796
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

IGF2R GBP4 PRKAA1 LRP2 PSMD1 ZMYM1 TASOR TNS1 CDK6

2.14e-03108491911544199
Pubmed

Deletion of Pdcd5 in mice led to the deficiency of placenta development and embryonic lethality.

HGF PRKAA1

2.28e-032791228542142
Pubmed

Transcriptome analysis in prenatal IGF1-deficient mice identifies molecular pathways and target genes involved in distal lung differentiation.

IGF2R IGFBP2

2.28e-032791224391734
Pubmed

Conditionals by inversion provide a universal method for the generation of conditional alleles.

PLXND1 ACVR1B

2.28e-032791223918385
Pubmed

Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes.

PKP4 NXPE2

2.28e-032791224550280
Pubmed

Genetic link between renal birth defects and congenital heart disease.

LRP2 PLXND1

2.45e-032891227002738
Pubmed

Primary cilia control telencephalic patterning and morphogenesis via Gli3 proteolytic processing.

LHX2 TFAP2E

2.45e-032891221490064
Pubmed

Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.

PCDHGB1 PCDHGA12

2.45e-032891215347688
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

IGF2R COPB1 SMARCAD1 TASOR

2.49e-0321591435973513
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

KPNA4 SMARCA5 COPB1 CCAR1 SMARCAD1 TBC1D23 CDK6

2.52e-0370491729955894
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SMARCA5 LZTR1 UACA PKP4 EPC1 LRP2 SMARCAD1 TF RNF43

2.60e-03111691931753913
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HGF SIGLEC9 VPS54 PLXND1 TNNI2 IFIT3 PALLD

1.24e-07189917a2f4f1dd5452f7efb7427919a0b90875cf2e1dc7
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HGF SIGLEC9 VPS54 PLXND1 TNNI2 IFIT3 PALLD

1.24e-0718991754a45b0cb7dea01caf1cf0a2664c40e5779a0b61
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

THBS2 STAMBPL1 ACTN2 SMOC2 TNS1 PALLD

1.90e-06180916d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellControl-PLT_4|Control / Disease Group and Platelet Clusters

KPNA4 PITHD1 ARHGAP32 KLHL24 PBX4 TIPARP

3.29e-06198916387fd3037fd52e4d4c42de0588767e58af228b59
ToppCelldroplet-Fat-Gat-18m-Hematologic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PITHD1 HGF SPHKAP NXPE2 TRIM10

2.19e-051649157dbe34a98a3b475c1ba678db8a5494c0c6a91e2d
ToppCelldroplet-Fat-Gat-18m-Hematologic-erythroblast|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PITHD1 HGF SPHKAP NXPE2 TRIM10

2.19e-05164915febcb8f8b305aa94e21131fa83d2890f7a6838fc
ToppCellNS-critical-d_0-4-Myeloid-Monocyte-derived_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LZTR1 STAMBPL1 IFIT3 PADI1 MCOLN2

2.60e-05170915adf73bdc049d508f8873c22539db2ca92052a97b
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

STAMBPL1 ACTN2 SMOC2 TNS1 PALLD

2.82e-05173915cb6389536195443633adb06e5f1b7483530773d1
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCNX2 PLCD3 CDRT4 IGFBP2 STAMBPL1

3.07e-0517691587de432c680b80555342afac864599bbc002c040
ToppCelldroplet-Spleen-nan-24m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMD4A ARHGAP32 TNNI2 TNS1 PADI1

3.32e-05179915d50d29f26d5a2cd8c4cd4e1244e1bb8de072d159
ToppCellCOVID-19_Severe-RBC|COVID-19_Severe / disease group, cell group and cell class

PITHD1 FRMD4A BSG TNS1 TRIM10

3.79e-05184915bb58244194ffb5558fbe85c5f856888210dcb1e8
ToppCellPBMC-Severe-Hematopoietic-RBC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PITHD1 FRMD4A TNS1 IFIT3 TRIM10

3.89e-05185915d685a5a2e525db2eba449cfa1e5cd54eb36162a8
ToppCell5'-Adult-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGFBP2 MUC5B SMOC2 RNF43 CDK6

3.89e-05185915655a9357a7711cefb48395e0b2a5a0ab90bcf3f5
ToppCellPBMC-Severe-Hematopoietic-RBC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PITHD1 FRMD4A TNS1 IFIT3 TRIM10

3.89e-051859155d8d6fd7800f76ee3aa5cef95241d8e6d7e8db04
ToppCellPBMC-Severe-Hematopoietic-RBC-RBC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PITHD1 FRMD4A TNS1 IFIT3 TRIM10

3.89e-05185915100b5afdf3c6ab07ffc493f7883f5a7b31c59184
ToppCellCOVID-19_Severe-Hematopoietic_R|COVID-19_Severe / Disease group, lineage and cell class

PITHD1 FRMD4A TNS1 IFIT3 TRIM10

3.89e-0518591530f064ab7c3890e6f419a845276b145112e78f52
ToppCellPBMC-Severe-Hematopoietic-RBC-RBC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PITHD1 FRMD4A TNS1 IFIT3 TRIM10

3.89e-05185915f3b1907c3b6f930bc161f46efce5e143babab507
ToppCellPBMC-Severe-Hematopoietic-RBC-RBC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PITHD1 FRMD4A TNS1 IFIT3 TRIM10

3.89e-0518591544ce50cb99df8ffc50eba311adcf688477618659
ToppCellPBMC-Severe-Hematopoietic-RBC-RBC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PITHD1 FRMD4A TNS1 IFIT3 TRIM10

3.89e-0518591517542ccd52a821c9e99b1a7469e80502e764b3fd
ToppCellCOVID-19_Severe-RBC|World / disease group, cell group and cell class

PITHD1 FRMD4A BSG TNS1 TRIM10

3.89e-0518591596b7058b1b282134970aa9e75285760a9f94a8b5
ToppCellCOVID-19_Severe-Hematopoietic_R-RBC|COVID-19_Severe / Disease group, lineage and cell class

PITHD1 FRMD4A TNS1 IFIT3 TRIM10

3.89e-051859153ed6090b822c6d1d400a421236cddc7511743932
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HGF THBS2 IGFBP2 STAMBPL1 PALLD

4.64e-051929154022f208eb5db760abd0aac782a25e8ab63efc64
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HGF THBS2 IGFBP2 STAMBPL1 PALLD

4.64e-051929159333aba0d04203ccccad78d82bf6359922f810a7
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DCHS2 THBS2 IGFBP2 SMOC2 HPSE

4.64e-0519291520ede290e01ad574afd122d72b59dbc52c595fad
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HGF DCHS2 THBS2 SMOC2 HPSE

4.76e-051939157cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCell10x3'2.3-week_12-13-Hematopoietic-erythroid-mid_erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FRMD4A BSG TNS1 TF TRIM10

4.76e-051939151e19f80c52833fb21a8d597a3ba2c4ff464c4559
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HGF THBS2 UACA SMOC2 PALLD

4.87e-05194915cf0244a29934e515446ac917d3c30672b460fb04
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Erythrocyte|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

PITHD1 FRMD4A BSG TNS1 TRIM10

4.87e-05194915f0ababe8daa57f6827a3e2e72c884d9e8b2687a3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HGF THBS2 UACA SMOC2 PALLD

4.87e-05194915ba7f971fb9a19423602da60770f23d9fead4a451
ToppCellMegakaryocytic-erythropoietic-Erythro-cells|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

PITHD1 FRMD4A BSG TNS1 TRIM10

5.12e-05196915092caba6726d1acd409a8be335100764d0724e64
ToppCellPBMC-Mild-cDC_0|Mild / Compartment, Disease Groups and Clusters

IGF2R IGFBP2 PLXND1 HPSE PALLD

5.37e-05198915fb873b7636bb1c7b119dd5b23d7a20f518e6c6da
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DCHS2 THBS2 IGFBP2 SMOC2 HPSE

5.37e-0519891512cd9f0bbad8dce5199ebfed1c4a8080710ca055
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

HGF ACTN2 TNS1 PALLD MCOLN2

5.50e-0519991530d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HGF UACA ACTN2 PALLD MCOLN2

5.63e-05200915e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellCOVID-19-COVID-19_Severe-Others-RBC|COVID-19_Severe / Disease, condition lineage and cell class

PITHD1 FRMD4A BSG TNS1 IFIT3

5.63e-05200915308f74e7e13ecc6d133c219c42cc8895a96644c8
ToppCellTracheal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HGF IGFBP2 PLXND1 SMOC2 TNS1

5.63e-052009159d3ae9ea47b1017adb63aa02d10e98193d478458
ToppCellTracheal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HGF IGFBP2 PLXND1 SMOC2 TNS1

5.63e-0520091578cd0b7d221ef855512ee9ac9a291f61622c2e24
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

HGF STAMBPL1 ACTN2 TNS1 MCOLN2

5.63e-05200915bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCellEndothelial-Endothelial-F|Endothelial / shred on cell class and cell subclass (v4)

HGF GBP4 UACA IFIT3

1.15e-041229142cb8bb63c69aed4d4504b9d97219b8707666f950
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-Uncommitted_AE_Progenitor|E18.5-samps / Age Group, Lineage, Cell class and subclass

PCDHGB1 TERB1 RNF43 PADI1

1.18e-041239145f002f5180fe47fe57ab888b5f0319df99ab2c59
ToppCellLPS-IL1RA-Endothelial-Epi-like-Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA LRP2 SMOC2 TIPARP

1.84e-041389145f8ac8f67e34a7cf560099208e6884102532391e
ToppCellmetastatic_Brain-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

THBS2 SIGLEC9 ZNF343 ACTN2

1.84e-04138914b2ab273f3e62f169b3b9cb82342e6617af99f582
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK|Hippocampus / BrainAtlas - Mouse McCarroll V32

GBP4 BSG NXPE2 MCOLN2

1.89e-0413991434398a6f21a1e670497655a7bb7f3cde9e117560
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

GBP4 BSG NXPE2 MCOLN2

1.89e-04139914450c4152c9fe4ec503271bb3cf93739918c59509
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Krt80|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HGF IGFBP2 CDKL4 TNS1

2.00e-0414191440ef6d792e11fe10963d64eb0b606b90556c1a70
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PCNX2 ARHGAP32 LRRIQ1 CDKL4

2.11e-041439145fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Erythrocyte|Erythro-cells / Lineage, cell class and subclass

FRMD4A BSG TNS1 TRIM10

2.17e-041449147fbedc65314cfb06bcc527d794b5de7858f7c5ec
ToppCellPericytes-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

PLCD3 THBS2 SMOC2 PALLD

2.53e-04150914dbc202bd6db4fb5c8b2abd1200e074a2a9e63a59
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Tnc|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HGF LHX2 PLXND1 SMOC2

2.80e-041549140066b2b8cfc74603e97f271ef5efc7ec512110dc
ToppCellControl-PLT_4|World / Disease Group and Platelet Clusters

KPNA4 ARHGAP32 KLHL24 TIPARP

2.80e-04154914a2a03c5e6759c45aeeedf1e68ecb5a0112ef9a20
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PCNX2 ARHGAP32 LRRIQ1 CDKL4

3.31e-04161914ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCelldroplet-Fat-Gat-18m-Hematologic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PITHD1 SPHKAP NXPE2 TRIM10

3.64e-041659141e89154114327650df39befb2c56d0379ea6a221
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

HGF DCHS2 PCDHGB1 SNX25

3.72e-0416691465dafed953b01a9830b54309af75c7a561e88336
ToppCellfacs-Heart-LV-24m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMB3 TNNI2 HPSE MCOLN2

3.81e-041679144a669eafde3582a451614ad304769b47aa1d9578
ToppCellControl-Myeloid-MoAM1,_IL1R2|Control / Condition, Lineage and Cell class

HGF GBP4 HPSE IFIT3

3.81e-04167914ab6029ba037b6a499da8758864c44e174cde5587
ToppCellControl-Myeloid-MoAM1,_IL1R2|Myeloid / Condition, Lineage and Cell class

HGF GBP4 HPSE IFIT3

3.81e-041679146e5140527437193f441ca96893b9a00d346614f3
ToppCellmild_COVID-19_(asymptomatic)-pDC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

FRMD4A IGFBP2 ASB12 MCOLN2

3.89e-04168914968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCellfacs-Heart-LV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMB3 TNNI2 HPSE MCOLN2

3.98e-04169914ae85cef7ef8f761c19f4af2a23fe333641c38a92
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SIGLEC9 KCNMB3 PLXND1 IFIT3

3.98e-04169914e3100eb587005e160bd0b7990fa57ec49765133d
ToppCellfacs-Heart-LV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMB3 TNNI2 HPSE MCOLN2

3.98e-04169914c01bc3f2f299109086ded83dc11e98559bf1940c
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ACTN2 PLXND1 TNS1 PALLD

4.07e-041709147fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCelldroplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMD4A ARHGAP32 TNNI2 PADI1

4.16e-041719144e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCN11A UACA PKP4 PLXND1

4.16e-04171914b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCelldroplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCD3 TNNI2 HPSE PADI1

4.25e-0417291424ecfda5e43e28f190089770cd2eae5bf2ed292b
ToppCelldroplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCD3 TNNI2 HPSE PADI1

4.25e-04172914db5a31cafce4346fe459d7f35210823fd7004439
ToppCellfacs-Marrow-T-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAMBPL1 TNNI2 TNS1 PALLD

4.35e-04173914ca3d2a9562734f76127e3e7d54c10b63e95141bb
ToppCellfacs-Marrow-T-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAMBPL1 TNNI2 TNS1 PALLD

4.35e-0417391419a9e10885173d7712996be8660a3a5a7a9aa39f
ToppCellRSV-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

GBP4 SIGLEC9 VPS54 IFIT3

4.54e-04175914ff3a27f512a3a710ebc863b7b75cce8167d5440b
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 UACA TNS1 PALLD

4.54e-041759141799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellRSV-Healthy-1|RSV / Virus stimulation, Condition and Cluster

GBP4 SIGLEC9 VPS54 IFIT3

4.54e-04175914ca52b99b03535a5b3a2751d6981708dc5b255b91
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDRT4 IGFBP2 BSG RPTN

4.54e-04175914442f261a3b2c4d2523f7d4089178f8c79cac2f0f
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDRT4 IGFBP2 BSG RPTN

4.54e-0417591435fb7735dd3355476fe60404833cb60bd066bcf1
ToppCell3'-Child09-12-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGFBP2 SMOC2 RNF43 CDK6

4.54e-041759140431897d7fcc9cefb516cd36987cf18b7f19a26a
ToppCelldroplet-Kidney-nan-21m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BSG PKP4 LRP2 TNS1

4.64e-041769140475db3f860de1e216cbdeb886f7a75b9f4fc801
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HGF THBS2 SMOC2 PALLD

4.64e-04176914b4a23d8d1414434adeb237a96f28c825f1aebd77
ToppCellwk_15-18-Hematologic-Meg-ery-Definitive_erythrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PITHD1 BSG TF TRIM10

4.64e-041769149af82b976e6a14a3ef7aa50f1f7af2463e5aa5d2
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HGF THBS2 SMOC2 PALLD

4.64e-0417691466c9c6b59030f67e8d746a9c6930e50923f2ded1
ToppCellControl-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

HGF PLXND1 TNS1 CDK6

4.74e-04177914470f54fe2b21c7350ea471e02039461a3808f700
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA5 GBP4 TASOR IFIT3

4.84e-0417891401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 UACA HPSE TASOR

4.94e-04179914025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCellCOVID-19_Moderate-RBC|World / disease group, cell group and cell class

PITHD1 BSG TNS1 TRIM10

4.94e-04179914932fa98c0981ef8ef1e4945cdd4ae8c6c0858251
ToppCellMultiple_Sclerosis-Other-RBC|Multiple_Sclerosis / Disease, Lineage and Cell Type

PITHD1 BSG TNS1 TRIM10

4.94e-0417991415763dc59ee6186416e203ffbb450ae4608eba59
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HGF THBS2 STAMBPL1 PALLD

5.05e-04180914280ff5c8f292be1b88120db5ff1788b750644856
ToppCellfacs-SCAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 OGFR HPSE IFIT3

5.05e-041809146c70b6b7480507fa94625013222ad338ee7dd1d9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HGF THBS2 STAMBPL1 PALLD

5.05e-04180914fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Red_blood_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PITHD1 BSG TNS1 TRIM10

5.15e-04181914577bf37a6594fad01251d2c66d8ccda8e949b6cf
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Red_blood_cells-RBC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PITHD1 BSG TNS1 TRIM10

5.15e-04181914f5dc7a650afe8837cb424981e50ad2c8b18c7c32
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HGF THBS2 SMOC2 PALLD

5.15e-04181914c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCellPericytes-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DCHS2 THBS2 ACTN2 SMOC2

5.15e-0418191435c470988a93381eefa300831aabb813fa1b90bd
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IQCA1L THBS2 SMOC2 TIPARP

5.15e-04181914ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRMD4A DCHS2 IGFBP2 PALLD

5.15e-041819145f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HGF THBS2 SMOC2 PALLD

5.15e-04181914c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRMD4A DCHS2 IGFBP2 PALLD

5.15e-04181914c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GBP4 UACA NXPE2 PLXND1

5.26e-04182914840427d1c23d60482c943ff006b14007ed44d247
ToppCellBasal|World / shred by cell class for mouse tongue

FRMD4A KLHL24 IGFBP2 TNS1

5.37e-04183914c6729a207526ff4aa48176207b9353176f631fea
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

GBP4 OGFR IFIT3 TIPARP

5.37e-041839148f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellCOVID-19_Moderate-RBC|COVID-19_Moderate / disease group, cell group and cell class

PITHD1 BSG TNS1 TRIM10

5.37e-041839140dc337cd3f4f7964b0a268139c7ddc0f58b6a279
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 MUC5B PKD1L2 OTOG

5.48e-041849142cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 MUC5B PKD1L2 OTOG

5.48e-04184914ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellPosterior_cortex-Neuronal-Excitatory|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PCNX2 ARHGAP32 LRRIQ1 CDKL4

5.48e-0418491425ccf08a8a26d7e7827b6357f33a53aaf423577d
DrugFluoxetine hydrochloride [59333-67-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A

PCNX2 FRMD4A ZNF16 KLHL24 LRP2 MUC5B MAP3K1 CDK6

1.11e-061969083314_UP
DrugMethoxy-6-harmalan [3589-73-9]; Up 200; 18.6uM; MCF7; HT_HG-U133A

HGF KLHL24 ZNF343 ACTN2 ACVR1B RNF43 PADI1

1.20e-051949072893_UP
DrugIndomethacin [53-86-1]; Down 200; 11.2uM; HL60; HT_HG-U133A

ZNF16 OGFR LRP2 PLXND1 ACVR1B PADI1 ZNF222

1.29e-051969072377_DN
Drug5149715; Up 200; 10uM; MCF7; HT_HG-U133A_EA

ZNF16 SMARCA5 RRN3 IL17RC VPS54 RNF43 ZNF222

1.42e-05199907890_UP
Drugheme As

UBR1 COPB1 KCNMB3 TF CDK6

1.85e-0582905CID006323354
Diseasehigh grade glioma (is_marker_for)

HGF RNF43 CDK6

2.62e-0442873DOID:3070 (is_marker_for)
Diseasebrain infarction (implicated_via_orthology)

HGF ADNP

4.65e-0411872DOID:3454 (implicated_via_orthology)
Diseaseclonal hematopoiesis mutation measurement

COP1 ATE1 HPSE

5.81e-0455873EFO_0020949
Diseaseneuroimaging measurement

DCHS2 LRRIQ1 PSMD1 SMARCAD1 PLXND1 ATE1 TNS1 TF MAP3K1 CDK6

1.20e-0310698710EFO_0004346
Diseaseanorectal malformation

THBS2 MUC5B

1.42e-0319872MONDO_0019938
Diseasecortical surface area measurement

HGF DCHS2 LRRIQ1 COPB1 CCAR1 SMARCAD1 PLXND1 SMOC2 TNS1 MAP3K1 CDK6

1.98e-0313458711EFO_0010736
DiseaseNeoplasm Invasiveness

HGF BSG HPSE TF

2.18e-03184874C0027626

Protein segments in the cluster

PeptideGeneStartEntry
ECNYNRLQHAVPADD

PKP4

491

Q99569
LRDAPAESVAYHAQN

ADNP

571

Q9H2P0
HQSLEDNNRCPKCNY

COP1

161

Q8NHY2
RCEDLPDLHEYASIN

EPC1

21

Q9H2F5
VDLLPENDHNLYVCD

B4GALT3

196

O60512
LDYHDAVNVNDRCQK

ACTN2

471

P35609
RENYVSCHDPNNNAP

CATSPERD

646

Q86XM0
YHKSCALAEDPQELR

CCAR1

461

Q8IX12
YHNRQRLDMEDPSCE

ACVR1B

156

P36896
EYCDHTLLNELERNP

CDKL4

81

Q5MAI5
AQENKHDSYIPCSER

GIT2

661

Q14161
SHPYFQDLERCKENL

CDK6

296

Q00534
AKAAAEYLCRQHADP

TFAP2E

321

Q6VUC0
DPCSLSVENENYARH

MUC5B

606

Q9HC84
LVNCDRDNHRSAEPD

PADI1

151

Q9ULC6
AHDPDCEENAQITYS

PCDHGA12

476

O60330
QEHLERFYCNPENDR

TIPARP

286

Q7Z3E1
LHADSRDCPTENYNK

CDRT4

121

Q8N9R6
GAADNTLPNELHCYD

LZTR1

301

Q8N653
LLLHGADPDYNCTDQ

ASB12

191

Q8WXK4
CATNQYLRKENDPHR

LMLN

146

Q96KR4
KLHQDQFTCPDEYED

PCNX2

1696

A6NKB5
QASCEHPRRLTDNYN

PLXND1

111

Q9Y4D7
RGDPECHLFYNEQQE

IGFBP2

301

P18065
CASNEDHKIAYDPSL

PCDHGB1

786

Q9Y5G3
VCDAYRKDLQHPNEF

COPB1

101

P53618
CNENDAEHLDRDQPY

LHX2

246

P50458
LENPAAVQRAADHYS

GBP4

336

Q96PP9
IPRAYVCDHDNDCQD

LRP2

196

P98164
DASKLNENYCRNPDD

HGF

431

P14210
NENYCRNPDDDAHGP

HGF

436

P14210
NRCNSYDNLPHDNES

ARHGAP32

746

A7KAX9
QHVDYSLRCEQDPEK

EXOC8

656

Q8IYI6
HCTNTDNPRYKEGDL

HPSE

436

Q9Y251
RNDQDYVLGRHAPCE

LRRIQ1

671

Q96JM4
DAVYGRQNPHFCTQD

PKD1L2

181

Q7Z442
NEHPYRKCSDSALSD

DCHS2

3111

Q6V1P9
SPGARHCYQDNQDLA

PALLD

236

Q8WX93
HCYQDNQDLAVPHNR

PALLD

241

Q8WX93
CPNDNSIEHSDYRAK

PBX4

116

Q9BYU1
TQALKEHPSLAYCED

FRMD4A

171

Q9P2Q2
QNSPECYQLLHEARR

KLHL24

276

Q6TFL4
CFHDDAPKDYRQVSL

CCNF

496

P41002
EVPDAEKQQSHQRYC

IFIT3

351

O14879
YECRASNDPDRNHLT

BSG

106

P35613
ENSKYCRFNQDPEAV

ATE1

446

O95260
YTPKCHQDRNDLLNS

KCNMB3

156

Q9NPA1
PYHDKFENLNTVAEC

MCOLN2

441

Q8IZK6
RYEKELNHTQQLPDC

IL17RC

251

Q8NAC3
EANQEYEHPRDLAAC

OTOG

2741

Q6ZRI0
RHNYPDLVERDCNGD

OGFR

76

Q9NZT2
SLQFHRNCPENKDSD

MAP3K1

1026

Q13233
NCEVKDPRHGNLYDL

IGF2R

1226

P11717
DDNLPANFDTCHRAL

RRN3

176

Q9NYV6
ECRGYNLQPDHDIQR

RGL2

476

O15211
EESIHPNTQEKYNCA

SPHKAP

876

Q2M3C7
LHDIDCNPYNDKQAE

SMARCAD1

946

Q9H4L7
CNPYNDKQAEDRCHR

SMARCAD1

951

Q9H4L7
DDRDQEAFYCVRPQH

NXPE2

246

Q96DL1
FCDLKAANARHEEQP

SNX25

71

Q9H3E2
KNRCESIHPSQNYDS

IQCA1L

406

A6NCM1
QQFPDNESEEYHRIC

POTEJ

421

P0CG39
DHYTKQCVENADLPE

PSMD1

106

Q99460
HPLYLCNASDDDNLE

RNF43

86

Q68DV7
DRYDPDHVCNASDNT

SELENOO

356

Q9BVL4
HLRDAAEFTCRAQNP

SIGLEC9

311

Q9Y336
QNKNYSAHLGECPRD

SLCO1B7

466

G3V0H7
YHNCDSQTRNAPELD

TASOR

1406

Q9UK61
EEVLSCLYNRNHQDP

PRKAA1

316

Q13131
RREAEKQNYLAEHCP

TNNI2

36

P48788
INCREYEPDHNLESN

ZNF343

241

Q6P1L6
EEYANCHLARAPNHA

TF

591

P02787
RCCNQYQESPHDAED

SPEM2

11

Q0P670
ICNYEASANPADHRV

PITHD1

186

Q9GZP4
PADCARQETDYVLNN

PLCD3

696

Q8N3E9
YEQPKCDNTARAHPA

SMOC2

276

Q9H3U7
NHRDYQQCAVPEKQD

STAMBPL1

91

Q96FJ0
VDCRPAEQYNAGHLS

TBC1D23

341

Q9NUY8
TDNACHLFAELDPNQ

TNS1

1701

Q9HBL0
NQASHFRCPRSADDE

UBR1

1606

Q8IWV7
LNHTEDEYECQACPN

TAS1R2

526

Q8TE23
LQYNCPTEHADLQGR

UACA

121

Q9BZF9
EDAAAPYREQIHKCL

TRIM10

136

Q9UDY6
HYQQPDCDTRTEDKE

ZNF16

61

P17020
SCRPETHISNDYGNN

ZNF765

181

Q7L2R6
RDCKNISNPEAYDHC

SCN11A

286

Q9UI33
TEPDNAQEYCHRQQS

ZMYM1

26

Q5SVZ6
CPYISNANQADHDRD

THBS2

876

P35442
CEKPIQDSHYGQSER

RPTN

231

Q6XPR3
YCRLDGQTPHDERQD

SMARCA5

526

O60264
KSANPVHACYRESEQ

TERB1

496

Q8NA31
YCKDQQRDHSGENPS

ZNF222

411

Q9UK12
YSHSDLNRPLEDDCQ

VPS54

361

Q9P1Q0
HCLERDDNPSLQFEA

KPNA4

121

O00629