Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	regulation of canonical Wnt signaling pathway	AMER1 HECW1 CTDNEP1 SOX13 CCDC88C ZNRF3 CSNK1G1 DACT3 CTNND2 WNK2	6.13e-06	285	119	10	GO:0060828
GeneOntologyBiologicalProcess	canonical Wnt signaling pathway	AMER1 HECW1 CTDNEP1 SOX13 CCDC88C ZNRF3 CSNK1G1 DACT3 CTNND2 WNK2	3.11e-05	344	119	10	GO:0060070
GeneOntologyBiologicalProcess	regulation of supramolecular fiber organization	ARHGEF5 PPFIA1 PLEKHG2 SHANK3 CCDC88C MAP1S MEGF9 KANK3 SORBS3 TNXB VASP	4.71e-05	438	119	11	GO:1902903
GeneOntologyBiologicalProcess	regulation of Wnt signaling pathway	AMER1 HECW1 CTDNEP1 SOX13 CCDC88C ZNRF3 CSNK1G1 DACT3 CTNND2 WNK2	5.49e-05	368	119	10	GO:0030111
GeneOntologyBiologicalProcess	actin filament-based process	ARHGEF5 PPFIA1 SH3KBP1 PLEKHG2 ECT2 SPECC1 SHANK3 CCDC88C LLGL2 MEGF9 KANK3 SORBS3 CACNA1H TNXB VASP KLHL17	7.04e-05	912	119	16	GO:0030029
GeneOntologyBiologicalProcess	regulation of cytoskeleton organization	ARHGEF5 PPFIA1 PARP3 PLEKHG2 ECT2 SHANK3 CCDC88C MAP1S MEGF9 KANK3 SORBS3 VASP	1.32e-04	579	119	12	GO:0051493
Domain	SH3_2	MIA3 ARHGEF5 SH3KBP1 SHANK3 MIA2 SORBS3	1.74e-05	86	118	6	PF07653
Domain	SH3_2	MIA3 ARHGEF5 SH3KBP1 SHANK3 MIA2 SORBS3	1.74e-05	86	118	6	IPR011511
Domain	HECW_N	HECW1 HECW2	3.96e-05	2	118	2	IPR032348
Domain	HECW_N	HECW1 HECW2	3.96e-05	2	118	2	PF16562
Domain	-	PSD2 ARHGEF5 SHC4 TNS2 PLEKHG2 PLEKHA6 ECT2 SBF1 TNS1 VASP	1.89e-04	391	118	10	2.30.29.30
Domain	WW	HECW1 BAG3 ARHGAP39 HECW2	2.19e-04	47	118	4	PF00397
Domain	FAM47	FAM47A FAM47C	2.36e-04	4	118	2	PF14642
Domain	Tensin_PTB	TNS2 TNS1	2.36e-04	4	118	2	IPR033929
Domain	FAM47	FAM47A FAM47C	2.36e-04	4	118	2	IPR032743
Domain	WW	HECW1 BAG3 ARHGAP39 HECW2	2.38e-04	48	118	4	SM00456
Domain	WW_DOMAIN_1	HECW1 BAG3 ARHGAP39 HECW2	3.01e-04	51	118	4	PS01159
Domain	WW_DOMAIN_2	HECW1 BAG3 ARHGAP39 HECW2	3.01e-04	51	118	4	PS50020
Domain	WW_dom	HECW1 BAG3 ARHGAP39 HECW2	3.24e-04	52	118	4	IPR001202
Domain	PH_dom-like	PSD2 ARHGEF5 SHC4 TNS2 PLEKHG2 PLEKHA6 ECT2 SBF1 TNS1 VASP	3.73e-04	426	118	10	IPR011993
Domain	SANT_dom	NCOR2 CRAMP1 ZNF541	5.75e-04	26	118	3	IPR017884
Domain	SANT	NCOR2 CRAMP1 ZNF541	7.18e-04	28	118	3	PS51293
Domain	PKD	PKD1L1 PMEL	8.14e-04	7	118	2	PF00801
Domain	PTEN_C2	TNS2 TNS1	1.08e-03	8	118	2	PF10409
Domain	PTB	TNS2 TNS1	1.08e-03	8	118	2	IPR013625
Domain	PTEN_C2	TNS2 TNS1	1.08e-03	8	118	2	SM01326
Domain	PTB	TNS2 TNS1	1.08e-03	8	118	2	PF08416
Domain	C2_TENSIN	TNS2 TNS1	1.08e-03	8	118	2	PS51182
Domain	Tensin_lipid_phosphatase_dom	TNS2 TNS1	1.08e-03	8	118	2	IPR029023
Domain	Tensin_C2-dom	TNS2 TNS1	1.08e-03	8	118	2	IPR014020
Domain	PPASE_TENSIN	TNS2 TNS1	1.38e-03	9	118	2	PS51181
Domain	PKD/Chitinase_dom	PKD1L1 PMEL	1.38e-03	9	118	2	IPR022409
Domain	PKD	PKD1L1 PMEL	1.38e-03	9	118	2	SM00089
Domain	VDCCAlpha1	CACNA1A CACNA1H	1.72e-03	10	118	2	IPR002077
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TMEM8B NLRX1 ZBTB4 PAPLN PPP6R1 PIGG MAST2 CTDNEP1 ZDHHC8 RASSF7 BAHD1 CCDC88C NCOR2 LLGL2 SLC2A4RG MAP1S SBF1 NFATC1 ZNRF3 KANK3 SORBS3 CACNA1H ATG9A CRAMP1 WNK2 PCNT KLHL17	1.99e-15	1105	124	27	35748872
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	SDK2 AMER1 PKD1L1 BAG3 MAST2 ECT2 MAP1S NSUN5P2 MTCL1 CTNND2 SRRM2 PRRC2A CPSF7	6.37e-10	361	124	13	26167880
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1A MIA3 HECW1 PPFIA1 SH3KBP1 PPP6R1 ARHGAP39 SHANK3 LUZP1 CCDC88C NCOR2 SBF1 MTCL1 CTNND2 TNS1 PRRC2A WNK2 PCNT	1.02e-08	963	124	18	28671696
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MIIP AMER1 ARHGEF5 PPFIA1 BAG3 PLEKHG2 MAST2 ECT2 SPECC1 RASSF7 LUZP1 PIK3R4 USP31 CCDC88C SBF1 MTCL1 SRRM2	1.23e-08	861	124	17	36931259
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	MIA3 PPFIA1 BAG3 TNS2 PPP6R1 ARHGAP39 CTDNEP1 LUZP1 USP31 NCOR2 SBF1 DDX54 SORBS3 SRRM2 TNS1 PRRC2A CBX8 PCNT	3.74e-08	1049	124	18	27880917
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	CACNA1A PSD2 DACH1 SHANK3 HSF1 SRRM2 CRAMP1 WNK2 NOTCH4	1.69e-07	233	124	9	37704626
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	CACNA1A SH3KBP1 BCAN ARHGAP39 PLEKHA6 SPECC1 ADCY5 CTNND2 SRRM2 PRRC2A	5.12e-07	347	124	10	17114649
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CACNA1A PPFIA1 SH3KBP1 BCAN ARHGAP39 PLEKHA6 SPECC1 SHANK3 LUZP1 PIK3R4 USP31 MAP1S SBF1 HECW2 CTNND2 TNS1 PRRC2A WNK2 CPSF7	7.85e-07	1431	124	19	37142655
Pubmed	Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.	COL4A1 PIGG NCOR2 LLGL2 SBF1 WNK2	1.25e-05	142	124	6	19851296
Pubmed	Tensin1 and a previously undocumented family member, tensin2, positively regulate cell migration.	TNS2 TNS1	1.26e-05	2	124	2	11792844
Pubmed	BAG3 expression and sarcomere localization in the human heart are linked to HSF-1 and are differentially affected by sex and disease.	BAG3 HSF1	1.26e-05	2	124	2	33989081
Pubmed	Association study between the TNXB locus and schizophrenia in a Japanese population.	TNXB NOTCH4	1.26e-05	2	124	2	17192952
Pubmed	2'-Hydroxycinnamaldehyde induces apoptosis through HSF1-mediated BAG3 expression.	BAG3 HSF1	1.26e-05	2	124	2	27922674
Pubmed	BAG3 affects the nucleocytoplasmic shuttling of HSF1 upon heat stress.	BAG3 HSF1	1.26e-05	2	124	2	26159920
Pubmed	Bag3 gene expression is regulated by heat shock factor 1.	BAG3 HSF1	1.26e-05	2	124	2	18286539
Pubmed	TANGO1 builds a machine for collagen export by recruiting and spatially organizing COPII, tethers and membranes.	MIA3 MIA2	1.26e-05	2	124	2	29513218
Pubmed	Association of genetic variants with hemorrhagic stroke in Japanese individuals.	COL4A1 PIGG NCOR2 LLGL2 SBF1 WNK2	1.30e-05	143	124	6	20198315
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	HECW1 RTEL1 PASK ZNRF3 RPRD2 UNC80 PCNT	1.71e-05	225	124	7	12168954
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SDK2 PHRF1 BAHD1 KIAA1614 PASK SBF1 HECW2 RPRD2 CRAMP1 WNK2	2.11e-05	529	124	10	14621295
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	MIA3 AMER1 PPFIA1 PPP6R1 MAST2 LUZP1 CCDC88C MAP1S MTCL1	3.34e-05	446	124	9	24255178
Pubmed	Association of MHC SNP genotype with susceptibility to type 1 diabetes: a modified survival approach.	PRRC2A TNXB NOTCH4	3.47e-05	18	124	3	19143821
Pubmed	Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci.	PRRC2A TNXB NOTCH4	3.47e-05	18	124	3	19116923
Pubmed	Dual function of cTAGE5 in collagen export from the endoplasmic reticulum.	MIA3 MIA2	3.77e-05	3	124	2	27170179
Pubmed	TANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulum.	MIA3 MIA2	3.77e-05	3	124	2	27138255
Pubmed	Association study between polymorphisms in the CACNA1A, CACNA1C, and CACNA1H genes and drug-resistant epilepsy in the Chinese Han population.	CACNA1A CACNA1H	3.77e-05	3	124	2	26216687
Pubmed	Distinct isoform-specific complexes of TANGO1 cooperatively facilitate collagen secretion from the endoplasmic reticulum.	MIA3 MIA2	3.77e-05	3	124	2	27413011
Pubmed	Promyogenic function of Integrin/FAK signaling is mediated by Cdo, Cdc42 and MyoD.	MYOD1 CDON	3.77e-05	3	124	2	21397010
Pubmed	BAG3 regulates contractility and Ca(2+) homeostasis in adult mouse ventricular myocytes.	CACNA1A BAG3	3.77e-05	3	124	2	26796036
Pubmed	The nuclear receptor corepressor N-CoR regulates differentiation: N-CoR directly interacts with MyoD.	MYOD1 NCOR2	3.77e-05	3	124	2	10406466
Pubmed	Association of single nucleotide polymorphisms in CACNA 1A/CACNA 1C/CACNA 1H calcium channel genes with diabetic peripheral neuropathy in Chinese population.	CACNA1A CACNA1H	3.77e-05	3	124	2	29581247
Pubmed	Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.	KANK3 PRRC2A TNXB NOTCH4	4.56e-05	55	124	4	14656967
Pubmed	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	PHRF1 TNXB NOTCH4	5.61e-05	21	124	3	21408207
Pubmed	DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.	COL4A1 RASSF7 PCNT	6.48e-05	22	124	3	12812986
Pubmed	A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.	PPFIA1 TNS2 LUZP1 NCOR2 PCNT	6.74e-05	118	124	5	30979931
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HECW1 RTEL1 ZBTB4 ZFP28 ARHGAP39 PLEKHA6 SHANK3 CCDC88C UNC80	7.22e-05	493	124	9	15368895
Pubmed	Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms.	CACNA1A CACNA1H	7.53e-05	4	124	2	31800012
Pubmed	Tensin3 is a negative regulator of cell migration and all four Tensin family members are downregulated in human kidney cancer.	TNS2 TNS1	7.53e-05	4	124	2	19194507
Pubmed	Foxc2 induces expression of MyoD and differentiation of the mouse myoblast cell line C2C12.	COL4A1 MYOD1	7.53e-05	4	124	2	17506979
Pubmed	cTAGE5 mediates collagen secretion through interaction with TANGO1 at endoplasmic reticulum exit sites.	MIA3 MIA2	7.53e-05	4	124	2	21525241
Pubmed	Concentration of Sec12 at ER exit sites via interaction with cTAGE5 is required for collagen export.	MIA3 MIA2	7.53e-05	4	124	2	25202031
Pubmed	TANGO1/cTAGE5 receptor as a polyvalent template for assembly of large COPII coats.	MIA3 MIA2	7.53e-05	4	124	2	27551091
Pubmed	Functional importance of L- and P/Q-type voltage-gated calcium channels in human renal vasculature.	CACNA1A CACNA1H	7.53e-05	4	124	2	21788606
Pubmed	Role of the Rho GTPase-activating protein RICS in neurite outgrowth.	PPP6R1 NFKBIE	7.53e-05	4	124	2	16716191
Pubmed	Activation of the beta myosin heavy chain promoter by MEF-2D, MyoD, p300, and the calcineurin/NFATc1 pathway.	MYOD1 NFATC1	7.53e-05	4	124	2	17111365
Pubmed	Pericentrin deficiency in smooth muscle cells augments atherosclerosis through HSF1-driven cholesterol biosynthesis and PERK activation.	HSF1 PCNT	7.53e-05	4	124	2	37937642
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	SDK2 SH3KBP1 ARHGAP39 ZDHHC8 SHANK3 CSNK1G1	7.85e-05	197	124	6	36604605
Pubmed	The CRL4DCAF6 E3 ligase ubiquitinates CtBP1/2 to induce apoptotic signalling and promote intervertebral disc degeneration.	MIA3 HMX3 PIGG ADCY5 NFATC1 SRRM2	8.30e-05	199	124	6	36688959
Pubmed	Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.	PPFIA1 NAB2 TNS2 SEZ6L2 RASSF7 MIA2 KLF13 SORBS3	1.02e-04	402	124	8	24722188
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	PPFIA1 NCOR2 RPRD2 SRRM2 CPSF7	1.07e-04	130	124	5	35545047
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	BAG3 PHRF1 ARHGAP39 HEXIM2 PASK NCOR2 MAP1S SORBS3 HSF1 SRRM2 PRRC2A	1.07e-04	774	124	11	15302935
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	MIA3 PPFIA1 PPP6R1 LUZP1 PASK MTCL1	1.09e-04	209	124	6	36779422
Pubmed	Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord.	PHRF1 ARHGAP39 CACNA1H	1.22e-04	27	124	3	19026994
Pubmed	NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1.	HECW1 HECW2	1.25e-04	5	124	2	14684739
Pubmed	The phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1.	TNS2 TNS1	1.25e-04	5	124	2	17190795
Pubmed	Characterization and expression pattern of the novel MIA homolog TANGO.	MIA3 MIA2	1.25e-04	5	124	2	15183315
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	ARHGEF5 NCOR2 ZNF469 MIA2 MAP1S VASP WNK2 PCNT	1.62e-04	430	124	8	35044719
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	CACNA1A PPFIA1 PARP3 MUC16 PLEKHA6 CSNK1G2-AS1 TNS1 TNXB UNC80	1.69e-04	552	124	9	10737800
Pubmed	STK40 Is a Pseudokinase that Binds the E3 Ubiquitin Ligase COP1.	BAG3 PPP6R1 MTCL1	1.85e-04	31	124	3	28089446
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	PLEKHA6 ZDHHC8 LUZP1 CTNND2 SRRM2 PRRC2A	1.87e-04	231	124	6	16452087
Pubmed	TANGO1 recruits Sec16 to coordinately organize ER exit sites for efficient secretion.	MIA3 MIA2	1.87e-04	6	124	2	28442536
Pubmed	The sinus venosus contributes to coronary vasculature through VEGFC-stimulated angiogenesis.	DACH1 NFATC1	1.87e-04	6	124	2	25377552
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	AMER1 BAG3 MAST2 MAP1S SBF1 PRRC2A	1.91e-04	232	124	6	25515538
Pubmed	Large-scale concatenation cDNA sequencing.	TMEM8B COX11 SEZ6L2 CCDC88C PASK KANK3 B3GAT1 CACNA1H CTNND2	2.09e-04	568	124	9	9110174
Pubmed	A "double adaptor" method for improved shotgun library construction.	TMEM8B COX11 SEZ6L2 CCDC88C PASK KANK3 B3GAT1 CACNA1H CTNND2	2.26e-04	574	124	9	8619474
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	MAP1S RPRD2 SRRM2 VASP CPSF7	2.35e-04	154	124	5	16055720
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	MIA3 AMER1 PKD1L1 PLEKHG2 MAST2 RASSF7 LUZP1 CCDC88C NFKBIE CBX8 PCNT	2.48e-04	853	124	11	28718761
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	PPFIA1 ECT2 PIK3R4 NCOR2 MTCL1 SRRM2 VASP PCNT CPSF7	2.50e-04	582	124	9	20467437
Pubmed	CLP-1 associates with MyoD and HDAC to restore skeletal muscle cell regeneration.	MYOD1 HEXIM2	2.62e-04	7	124	2	20940258
Pubmed	ProSAPiP2, a novel postsynaptic density protein that interacts with ProSAP2/Shank3.	SHANK3 CTNND2	2.62e-04	7	124	2	19481056
Pubmed	Positive regulation of myogenic bHLH factors and skeletal muscle development by the cell surface receptor CDO.	MYOD1 CDON	2.62e-04	7	124	2	15572127
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	MIA3 AMER1 RTEL1 TMEM8B ARHGAP39 HEXIM2 NCOR2 NFATC1 RPRD2 CACNA1H GREB1 RPS6KL1 CRAMP1 WNK2 PCNT	2.78e-04	1489	124	15	28611215
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	SPECC1 MAP1S DDX54 SPTY2D1 PCNT CPSF7	2.92e-04	251	124	6	31076518
Pubmed	A protein-RNA interaction atlas of the ribosome biogenesis factor AATF.	PHRF1 RPRD2 SRRM2 PRRC2A CPSF7	2.97e-04	162	124	5	31363146
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	MIA3 LUZP1 BLVRB SRRM2 PRRC2A PCNT CPSF7	3.21e-04	360	124	7	33111431
Pubmed	Lysine acetylation targets protein complexes and co-regulates major cellular functions.	PIK3R4 SRRM2 VASP	3.41e-04	38	124	3	19608861
Pubmed	Netrins and neogenin promote myotube formation.	MYOD1 CDON	3.48e-04	8	124	2	15520228
Pubmed	Divergent hTAFII31-binding motifs hidden in activation domains.	NFATC1 HSF1	3.48e-04	8	124	2	10821850
Pubmed	Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3.	TNXB NOTCH4	3.48e-04	8	124	2	22694956
Pubmed	Protein phosphatase 6 subunit with conserved Sit4-associated protein domain targets IkappaBepsilon.	PPP6R1 NFKBIE	3.48e-04	8	124	2	16769727
Pubmed	Mice develop normally without tenascin.	COL4A1 TNXB	3.48e-04	8	124	2	1383086
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1A CACNA1H	4.47e-04	9	124	2	16382099
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	BAG3 PLEKHA6 ECT2 SORBS3 RPRD2 MTCL1 SRRM2 PRRC2A	4.61e-04	503	124	8	16964243
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SDK2 ZBTB4 PHRF1 CCDC88C	5.18e-04	103	124	4	10819331
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	AMER1 BAG3 PPP6R1 PLEKHA6 SPECC1 LUZP1 HEXIM2 NCOR2 DDX54 SRRM2 PRRC2A VASP CPSF7	5.26e-04	1247	124	13	27684187
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	MIA3 ARHGEF5 PAPLN PPP6R1 MAST2 ECT2 PIK3R4 LLGL2 SBF1	5.56e-04	650	124	9	38777146
Pubmed	Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area.	BCAN B3GAT1	5.57e-04	10	124	2	20950796
Pubmed	Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression.	NCOR2 NFKBIE	5.57e-04	10	124	2	15536134
Pubmed	Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.	SH3KBP1 KLF13 SRRM2 PRRC2A	6.20e-04	108	124	4	19531213
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PPP6R1 USP31 MEGF9 CACNA1H MTCL1 SRRM2 PCNT	6.65e-04	407	124	7	12693553
Pubmed	NEDL2 is an essential regulator of enteric neural development and GDNF/Ret signaling.	HECW1 HECW2	6.79e-04	11	124	2	25555806
Pubmed	Variants in LRRC7 lead to intellectual disability, autism, aggression and abnormal eating behaviors.	SHANK3 CTNND2	6.79e-04	11	124	2	39256359
Pubmed	Non-apical mitoses contribute to cell delamination during mouse gastrulation.	COL4A1 ECT2	6.79e-04	11	124	2	39198421
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	SH3KBP1 ZFP28 PPP6R1 ZNF784 MAST2 BAHD1 CCDC88C SBF1 CSNK1G1 ATG9A CTNND2 TNS1	7.05e-04	1124	124	12	21900206
Pubmed	Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.	RTEL1 PLEKHA6 SLC2A4RG TNXB NOTCH4	7.92e-04	201	124	5	23535732
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	MUC16 MAST2 USP31 SBF1 HECW2 SRRM2 UNC80	7.99e-04	420	124	7	28065597
Pubmed	Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts.	DACH1 NFATC1	8.13e-04	12	124	2	28890073
Pubmed	A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.	AMER1 RTEL1 ZNRF3 TGM7 SRRM2 SPTY2D1 CPSF7	9.28e-04	431	124	7	33660365
Pubmed	AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair.	AMER1 PPP6R1 SOX13 SHANK3	9.48e-04	121	124	4	31900314
Pubmed	Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.	COL4A1 MYOD1	9.59e-04	13	124	2	9833687
Pubmed	Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice.	MIA3 MIA2	9.59e-04	13	124	2	11839810
Interaction	TOP3B interactions	RTEL1 TMEM8B NLRX1 ZBTB4 PAPLN PPP6R1 PIGG MAST2 CTDNEP1 ZDHHC8 RASSF7 BAHD1 CCDC88C NCOR2 LLGL2 SLC2A4RG MAP1S SBF1 NFATC1 ZNRF3 KANK3 SORBS3 CACNA1H ATG9A PRRC2A CRAMP1 WNK2 PCNT KLHL17	1.24e-08	1470	123	29	int:TOP3B
Interaction	YWHAH interactions	MIIP AMER1 ARHGEF5 PPFIA1 BAG3 TNS2 PLEKHG2 MAST2 ECT2 SPECC1 RASSF7 LUZP1 PIK3R4 USP31 CCDC88C SBF1 MTCL1 ATG9A SRRM2 WNK2 PCNT	3.08e-06	1102	123	21	int:YWHAH
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	RASGRP4 ZFP28 PPP6R1 PLEKHG2 ZNF784 BLVRB SSC5D DACT3 CEACAM16 VASP ZNF541	4.04e-04	1192	124	11	chr19q13
Cytoband	16p13.3	PRR25 CACNA1H SRRM2 CRAMP1 SEC14L5	5.48e-04	244	124	5	16p13.3
GeneFamily	C2 tensin-type domain containing\|PTEN protein phosphatases\|Phosphoinositide phosphatases	TNS2 TNS1	1.87e-04	5	79	2	902
GeneFamily	DNAJ (HSP40) heat shock proteins\|C2 tensin-type domain containing	TNS2 TNS1	5.19e-04	8	79	2	837
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	NCOR2 CRAMP1 ZNF541	1.61e-03	53	79	3	532
GeneFamily	Zinc fingers C2H2-type\|Kruppel like factors	KLF14 KLF13	2.76e-03	18	79	2	624
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF5 PLEKHG2 ECT2	3.01e-03	66	79	3	722
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_GHRL_POS_NE_PRECURSOR_CELL	CACNA1A CCDC28B DACH1 PPP6R1 SEZ6L2 SPECC1 ZDHHC8 BAHD1 MEGF9 CACNA1H UNC80 WNK2	8.13e-07	429	122	12	M45694
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A1 DACH1 JPH2 TNS2 SOX13 ADCY5 CACNA1H TNS1 WNK2	2.87e-09	187	124	9	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	RASGRP4 PARP3 PAPLN SHANK3 SCARF1 SSC5D KANK3 DACT3 NOTCH4	3.01e-09	188	124	9	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|368C / Donor, Lineage, Cell class and subclass (all cells)	AVPR2 DACH1 SHANK3 SCARF1 PASK HECW2 KANK3 NOTCH4	2.22e-08	166	124	8	30a991fc3275b571d53bd0976df4789e5d40b01d
ToppCell	368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	AVPR2 DACH1 SHANK3 SCARF1 PASK HECW2 KANK3 NOTCH4	2.22e-08	166	124	8	76b4cd32698900797ec009f17e50ea7ae36b85f4
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-Late_cap\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	COL4A1 AVPR2 SHANK3 SCARF1 USP31 HECW2 KANK3 NOTCH4	4.73e-08	183	124	8	3e69cc605f166a1f04e3d077935f7cfd806f1ffd
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL4A1 PSD2 AVPR2 DACH1 TNS2 SHANK3 KANK3 NOTCH4	5.37e-08	186	124	8	a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A1 PSD2 JPH2 SHC4 ADCY5 USP31 MTCL1 TNS1	8.36e-08	197	124	8	f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCell	tumor_Lung-Endothelial_cells-Tip-like_ECs\|tumor_Lung / Location, Cell class and cell subclass	COL4A1 AVPR2 DACH1 SHANK3 SCARF1 HECW2 KANK3 NOTCH4	8.36e-08	197	124	8	353b76ca3e2aa4b8f51396e7121c4baa114083a0
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL4A1 DACH1 TNS2 SHANK3 SCARF1 HECW2 KANK3 NOTCH4	8.69e-08	198	124	8	72e8b9cccb7b0a2ea9d415218fff4fa2f09728f4
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1A SLC2A7 SEZ6L2 CTNND2 SRRM3 RPS6KL1 UNC80	3.21e-07	159	124	7	7747cef94c55144fddcd024a7495318357f1351b
ToppCell	COVID-19-Heart-VSMC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL4A1 CACNA1A JPH2 SPECC1 ADCY5 DACT3 CACNA1H	6.13e-07	175	124	7	1125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 AVPR2 MUC16 TNS2 SHANK3 KANK3 NOTCH4	6.87e-07	178	124	7	360d7a987f91d6d721487a921824057ec31a7332
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL4A1 PLEKHG2 SHANK3 LUZP1 USP31 HECW2 KANK3	7.41e-07	180	124	7	d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCell	Endothelial-A-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	COL4A1 DACH1 HECW2 KANK3 TNXB ZNF541 NOTCH4	7.41e-07	180	124	7	4c3376169770ee9f9283daae44c17f35e46bfd19
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 AVPR2 SHANK3 SCARF1 HECW2 KANK3 NOTCH4	9.91e-07	188	124	7	0026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DACH1 SHANK3 USP31 HECW2 KANK3 CTNND2 NOTCH4	9.91e-07	188	124	7	789d1be574e693d7bdd488f3c72c6df788e47b47
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D122\|Adult / Lineage, Cell type, age group and donor	COL4A1 DACH1 SHANK3 HECW2 KANK3 MTCL1 NOTCH4	9.91e-07	188	124	7	02a62888e9db29d20133eeca1686d302545a39c9
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	COL4A1 DACH1 JPH2 PAPLN CCDC88C SSC5D MTCL1	1.03e-06	189	124	7	b6d5dec55bf352f6ae19d8f488ae70aa10fb9a8f
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DACH1 SHANK3 USP31 HECW2 KANK3 CTNND2 NOTCH4	1.03e-06	189	124	7	e82211b9dc7540e7a183be2cbcfae39fdf503949
ToppCell	human_hepatoblastoma-Endothelial_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	COL4A1 JPH2 SHANK3 NFATC1 HECW2 KANK3 NOTCH4	1.06e-06	190	124	7	8d6ef93d69e96cd6921816d152bea3b0710cf147
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DACH1 SHANK3 LUZP1 USP31 HECW2 KANK3 NOTCH4	1.10e-06	191	124	7	1de0bdfd13bd930691564c2673f2e66393bc0255
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL4A1 PLEKHG2 SHANK3 USP31 HECW2 KANK3 NOTCH4	1.18e-06	193	124	7	ad2df9b77999780860141be6ec366afc0172a331
ToppCell	(6)_Endothelial-C_(Capillary_Aerocyte_)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	COL4A1 DACH1 SHANK3 SCARF1 HECW2 KANK3 NOTCH4	1.18e-06	193	124	7	f7f2dc6aff02d096a282835094d26d12b3b73e61
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A1 DACH1 SOX13 SHANK3 HECW2 KANK3 NOTCH4	1.22e-06	194	124	7	71ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-myocytic\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 JPH2 ADCY5 SSC5D DACT3 MTCL1 TNS1	1.31e-06	196	124	7	20dc9b25ecc23b6e6e52bbab8b5a404f3245ca37
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL4A1 DACH1 SHANK3 USP31 HECW2 KANK3 NOTCH4	1.35e-06	197	124	7	6a3c647af41fea923311562575a0d656fbc13cbe
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A1 CACNA1A JPH2 ADCY5 DACT3 CACNA1H TNS1	1.40e-06	198	124	7	7dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-intermediate_cap\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL4A1 SHANK3 SCARF1 USP31 HECW2 KANK3 NOTCH4	1.40e-06	198	124	7	a75499f8f1630359b64717c300621aa3b1ab44d4
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-intermediate_cap\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL4A1 AVPR2 SHANK3 SCARF1 HECW2 KANK3 NOTCH4	1.40e-06	198	124	7	75270600b5b29187dfa86f01f8f927ae0621cda4
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A1 DACH1 SHANK3 HECW2 KANK3 TNXB NOTCH4	1.45e-06	199	124	7	7ed541309808f15d65a9c4b26be2050e077539e6
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL4A1 SHANK3 SCARF1 HECW2 KANK3 CRAMP1 NOTCH4	1.45e-06	199	124	7	d95d78b2ebc9a20532466e4d4be579b4faf6776f
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL4A1 SHANK3 SCARF1 HECW2 KANK3 CRAMP1 NOTCH4	1.45e-06	199	124	7	cdcfca94baba66e213cc3ffb0cfb4c75d6ab44ec
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A1 DACH1 SHANK3 HECW2 KANK3 TNXB NOTCH4	1.45e-06	199	124	7	14a7c4cf4bb3d43fd32ec9cc74f6625b225ffaa1
ToppCell	Tracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A1 PLEKHG2 SEZ6L2 BAHD1 SSC5D DACT3 CRAMP1	1.50e-06	200	124	7	410b1a31de21c57d87ca2104f61cf4a7d4dd2f30
ToppCell	distal-Endothelial-Capillary_Intermediate_1-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL4A1 DACH1 SHANK3 LUZP1 HECW2 KANK3 NOTCH4	1.50e-06	200	124	7	43bc48413b100a06f8edd9acd812296788fcbf5b
ToppCell	Biopsy_IPF-Endothelial\|Biopsy_IPF / Sample group, Lineage and Cell type	COL4A1 TNS2 SHANK3 HECW2 KANK3 TNXB NOTCH4	1.50e-06	200	124	7	7ccd3b617838b39da814278dc0e12384013401ce
ToppCell	distal-Endothelial-Capillary_Intermediate_1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL4A1 DACH1 SHANK3 LUZP1 HECW2 KANK3 NOTCH4	1.50e-06	200	124	7	4d6714d48738cdee7d535923f6dd2431e5304741
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BCAN SHANK3 ZNF469 KANK3 TNXB NOTCH4	6.24e-06	162	124	6	c399b9e4854916a59f5cae2d8dbf19660f8759be
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BCAN SHANK3 ZNF469 KANK3 TNXB NOTCH4	6.24e-06	162	124	6	a291248b693c771845174393934a782f1d8bd7ce
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1A TMPRSS12 CACNA1H GREB1 SRRM3 UNC80	7.43e-06	167	124	6	c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 SHANK3 SCARF1 HECW2 KANK3 NOTCH4	8.51e-06	171	124	6	b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCell	Control-Endothelial_cells-Systemic_venous_endothelial_cells\|Control / group, cell type (main and fine annotations)	COL4A1 SLC2A7 PKD1L1 DACH1 SHANK3 NOTCH4	8.80e-06	172	124	6	c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1A JPH2 SOX13 ADCY5 DACT3 WNK2	9.09e-06	173	124	6	fc2602b2ce051cd4c33957d7e3d041ff8a529883
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEZ6L2 SHANK3 PASK HECW2 RPS6KL1 CRAMP1	9.09e-06	173	124	6	66488d01e03264fb193285470901c9c4182fbae8
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1A JPH2 SOX13 ADCY5 DACT3 WNK2	9.09e-06	173	124	6	901b8e6909c1f3849906fad9cee17b8f0bab050d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PKD1L1 TNS2 SHANK3 HECW2 TNXB NOTCH4	9.71e-06	175	124	6	90302e8a44858ef3b2a165b88284d4788d591a99
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A1 KLF14 JPH2 TNS2 CACNA1H TNS1	1.04e-05	177	124	6	452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AVPR2 SHANK3 SCARF1 HECW2 KANK3 NOTCH4	1.14e-05	180	124	6	755050226eeb1991ee7f0d15e39d0458f3e4a791
ToppCell	368C-Endothelial_cells-Endothelial-E\|368C / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 RTEL1 AVPR2 SCARF1 KANK3 NOTCH4	1.14e-05	180	124	6	8ab16a0b9053bffc07b569a4f9e71749f56dde7e
ToppCell	368C-Endothelial_cells-Endothelial-E-\|368C / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 RTEL1 AVPR2 SCARF1 KANK3 NOTCH4	1.14e-05	180	124	6	394cd465b88429b70eebb2957480dffcbc51cfe7
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 SHANK3 SCARF1 CCDC88C KANK3 NOTCH4	1.18e-05	181	124	6	9bfd93cf053beaee806cacdffd7abef02f94aec6
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A1 SDK2 PAPLN ADCY5 SSC5D TNXB	1.18e-05	181	124	6	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	COVID-19-Heart-EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL4A1 DACH1 SPECC1 SHANK3 CACNA1H NOTCH4	1.21e-05	182	124	6	e67f3234165199085c793915ebb1f9bbd845e933
ToppCell	tumor_Lymph_Node_/_Brain-Endothelial_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	COL4A1 AVPR2 SHANK3 SCARF1 KANK3 NOTCH4	1.21e-05	182	124	6	d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A1 DACH1 SHANK3 HECW2 KANK3 NOTCH4	1.21e-05	182	124	6	a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCell	5'-Adult-LymphNode-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZBTB4 PAPLN DACT3 CACNA1H SRRM3 CDON	1.25e-05	183	124	6	d67454baf0cf791a743b51afd1cb25bfb5765385
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SHANK3 SCARF1 ZNF469 HECW2 KANK3 NOTCH4	1.25e-05	183	124	6	dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SHANK3 SCARF1 ZNF469 HECW2 KANK3 NOTCH4	1.25e-05	183	124	6	4759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCell	5'-Adult-LymphNode-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZBTB4 PAPLN DACT3 CACNA1H SRRM3 CDON	1.25e-05	183	124	6	e49ac8314b6fe98426b1514ea68d646297b8bc0f
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 SHANK3 SCARF1 HECW2 KANK3 NOTCH4	1.29e-05	184	124	6	fa38d6a8709f520a027ad7e3ff783c84187ec467
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL4A1 SHANK3 KANK3 TNS1 RPS6KL1 NOTCH4	1.33e-05	185	124	6	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D231\|Adult / Lineage, Cell type, age group and donor	COL4A1 DACH1 SHANK3 HECW2 KANK3 NOTCH4	1.33e-05	185	124	6	07f9f38f0739d7c830641723a38385550ac1ac92
ToppCell	356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 DACH1 SHANK3 HECW2 KANK3 NOTCH4	1.37e-05	186	124	6	f0b78c7ee20279970ea8961bf59acb5262f2dce5
ToppCell	Control-Endothelial_cells-Endothelial_cells_(other)\|Control / group, cell type (main and fine annotations)	COL4A1 DACH1 SHANK3 HECW2 KANK3 NOTCH4	1.37e-05	186	124	6	c6075fe84226b370c5139066793844ad33ae2db1
ToppCell	356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 DACH1 SHANK3 HECW2 KANK3 NOTCH4	1.37e-05	186	124	6	2b3c814a7dee8286ea113c63dc3de5daf0257d37
ToppCell	tumor_Lymph_Node_/_Brain-Endothelial_cells-Tumor_ECs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	COL4A1 AVPR2 SHANK3 SCARF1 KANK3 NOTCH4	1.41e-05	187	124	6	be5f8c5802b0fa8cc1e274fdf06b13eb8ceb8ad4
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A1 DACH1 SHANK3 HECW2 KANK3 NOTCH4	1.46e-05	188	124	6	117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DACH1 SHANK3 SCARF1 KANK3 TNS1 NOTCH4	1.46e-05	188	124	6	05de6677f9bb4b00fed47f4b72f4a2cd507cb0f2
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Adult / Lineage, Cell type, age group and donor	COL4A1 DACH1 SHANK3 HECW2 KANK3 NOTCH4	1.46e-05	188	124	6	e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A1 DACH1 TNS2 ADCY5 CACNA1H TNS1	1.46e-05	188	124	6	ee151792c7ac9afe820f1a281c6dab383799f358
ToppCell	Endothelial-A-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	COL4A1 SHANK3 HECW2 KANK3 TNXB NOTCH4	1.46e-05	188	124	6	0824d567356d360fd8e78e840c30529c139f98a1
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 SHANK3 CCDC88C HECW2 KANK3 NOTCH4	1.50e-05	189	124	6	db09d591b885ce2bc9e353f08b6694e2192582e1
ToppCell	3'-Adult-Distal_Rectal-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 CACNA1A JPH2 TNS2 DACT3 TNS1	1.50e-05	189	124	6	d69b7a01dd4d6ad043bb6210e9ab34b49578389c
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHANK3 SCARF1 CCDC88C HECW2 KANK3 NOTCH4	1.50e-05	189	124	6	9e58411e51019ca59e78d3e737d65d2bcbbea2be
ToppCell	3'-Adult-Distal_Rectal-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 CACNA1A JPH2 TNS2 DACT3 TNS1	1.50e-05	189	124	6	2b5f1b4f173a224342ea4f10b193ee33b7662699
ToppCell	3'-Adult-Distal_Rectal-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 CACNA1A JPH2 TNS2 DACT3 TNS1	1.50e-05	189	124	6	43e131458d8a4b120f7a5fb3d0c5650abded15f6
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(general)\|COVID-19 / group, cell type (main and fine annotations)	COL4A1 DACH1 SHANK3 HECW2 KANK3 NOTCH4	1.55e-05	190	124	6	812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL4A1 DACH1 TNS2 ADCY5 CACNA1H TNS1	1.55e-05	190	124	6	4eb92aef1ee868f4537483d19014d947b7684612
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DACH1 SHANK3 HECW2 KANK3 CTNND2 NOTCH4	1.55e-05	190	124	6	a3c6eec6df052105ab78b7e3c78f94218d5912eb
ToppCell	COVID-19-Heart-EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	DACH1 SPECC1 SOX13 SHANK3 CACNA1H NOTCH4	1.55e-05	190	124	6	a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL4A1 DACH1 TNS2 ADCY5 CACNA1H TNS1	1.55e-05	190	124	6	7be4341e2909101d756f14031c21e705eb45e69a
ToppCell	Control-Endothelial-VE_Capillary_B\|World / Disease state, Lineage and Cell class	COL4A1 DACH1 SHANK3 HECW2 KANK3 NOTCH4	1.59e-05	191	124	6	c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCell	Control-Endothelial-VE_Capillary_B\|Control / Disease state, Lineage and Cell class	COL4A1 DACH1 SHANK3 HECW2 KANK3 NOTCH4	1.59e-05	191	124	6	322237793a1278bafb14e63cab688b353e352dcc
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 SHANK3 SCARF1 KANK3 TNS1 NOTCH4	1.64e-05	192	124	6	8f20d3511dcb44445592b17d005a53da0052ae56
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX13 SHANK3 SCARF1 CCDC88C KANK3 NOTCH4	1.64e-05	192	124	6	5a0615fdc217554ccd611504b16e5d97628e207d
ToppCell	human_hepatoblastoma-Endothelial_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	COL4A1 SHANK3 NFATC1 HECW2 KANK3 NOTCH4	1.64e-05	192	124	6	e09f609fed033a25baacaf4a07bbbae1076da366
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial-endothelial_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 SHANK3 SCARF1 KANK3 TNS1 NOTCH4	1.64e-05	192	124	6	0986b7900021efe2a4df84a935e7c9a0af1b0e57
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 SHANK3 SCARF1 HECW2 KANK3 NOTCH4	1.64e-05	192	124	6	1f35efb0765e05f7f9c881849953bef3965be25a
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 SHANK3 SCARF1 KANK3 TNS1 NOTCH4	1.64e-05	192	124	6	b28d294e42b303d1db6060231d84d7b9e4d9fccf
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL4A1 DACH1 SHANK3 HECW2 KANK3 NOTCH4	1.69e-05	193	124	6	f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCell	facs-BAT-Fat-3m-Endothelial-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 TNS2 LUZP1 KANK3 SORBS3 TNS1	1.69e-05	193	124	6	e340064cd146deac03f2d0fd43e2e218bb6057c9
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)\|Adult / Lineage, Cell type, age group and donor	COL4A1 DACH1 SHANK3 HECW2 KANK3 NOTCH4	1.69e-05	193	124	6	39c6c96a2a100b1b290a779d36cc6bc17245720b
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 SHANK3 SCARF1 HECW2 KANK3 NOTCH4	1.69e-05	193	124	6	dd443b83d328a9069ffe19ac3d74066e922515a5
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DACH1 SHANK3 USP31 HECW2 KANK3 NOTCH4	1.69e-05	193	124	6	ff6e6b825d6c88148216c601580be3c28851ab5c
ToppCell	facs-BAT-Fat-3m-Endothelial-endothelial_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 TNS2 LUZP1 KANK3 SORBS3 TNS1	1.69e-05	193	124	6	a211b386fd0fb9da9937361d29d90925a72c9715
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL4A1 DACH1 SHANK3 HECW2 KANK3 NOTCH4	1.69e-05	193	124	6	ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	COL4A1 SHANK3 HECW2 KANK3 TNS1 NOTCH4	1.69e-05	193	124	6	479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCell	facs-BAT-Fat-3m-Endothelial\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 TNS2 LUZP1 KANK3 SORBS3 TNS1	1.69e-05	193	124	6	3086c33f4d6fab66966818737f95ae4d6b2615b0
ToppCell	LPS-IL1RA-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL4A1 DACH1 SHANK3 HECW2 CTNND2 NOTCH4	1.74e-05	194	124	6	43f92b0533e26633dc94cce554045d641ef8fd76
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DACH1 SOX13 SHANK3 HECW2 KANK3 NOTCH4	1.74e-05	194	124	6	68004855b23fe1e31e8452d70effabc78a4a0bd3
Drug	Atovaquone [95233-18-4]; Down 200; 11uM; PC3; HT_HG-U133A	TNS2 SOX13 PASK KLF13 SORBS3 TNS1 CBX8 CPSF7	9.88e-06	195	121	8	4201_DN
Drug	Piretanide [55837-27-9]; Down 200; 11uM; MCF7; HT_HG-U133A	NAB2 MAST2 RASSF7 LUZP1 SBF1 CACNA1H GREB1 CBX8	1.03e-05	196	121	8	3567_DN
Drug	Hesperidin [520-26-3]; Down 200; 6.6uM; MCF7; HT_HG-U133A	MIIP RTEL1 NAB2 PMEL RASSF7 SBF1 MEGF9 SRRM2	1.03e-05	196	121	8	2648_DN
Drug	Alprostadil [745-65-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A	HECW1 CCDC28B NLRX1 PARP3 NCOR2 MAP1S SBF1 CACNA1H	1.06e-05	197	121	8	7358_UP
Drug	pentasulfane	CACNA1A B3GAT1 CACNA1H	7.80e-05	16	121	3	CID000448216
Drug	SnBu2H2	DACH1 NFATC1 CRAMP1	7.80e-05	16	121	3	CID000006513
Drug	Amprolium hydrochloride [137-88-2]; Down 200; 12.6uM; PC3; HT_HG-U133A	TNS2 SOX13 KLF13 SORBS3 CBX8 CDON CPSF7	7.89e-05	193	121	7	4241_DN
Drug	carmustine; Down 200; 100uM; PC3; HT_HG-U133A	MIIP COL4A1 TMEM8B LUZP1 MIA2 CTNND2 TNS1	8.15e-05	194	121	7	6883_DN
Drug	Imipenem [74431-23-5]; Down 200; 13.4uM; HL60; HG-U133A	MIIP MIA3 HECW1 ECT2 LUZP1 PASK VASP	8.15e-05	194	121	7	1724_DN
Drug	Pirenperone [ 75444-65-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A	MIA3 DACH1 PLEKHA6 CACNA1H GREB1 SRRM2 CBX8	8.15e-05	194	121	7	3316_DN
Drug	GSK-3 Inhibitor IX; Up 200; 0.5uM; MCF7; HT_HG-U133A	TNS2 MAP1S SBF1 MEGF9 DDX54 CACNA1H VASP	8.15e-05	194	121	7	7044_UP
Drug	Cefoperazone dihydrate; Down 200; 5.8uM; MCF7; HT_HG-U133A	RTEL1 DACH1 PLEKHA6 MIA2 MAP1S SBF1 SORBS3	8.41e-05	195	121	7	5424_DN
Drug	Sulfamerazine [127-79-7]; Down 200; 15.2uM; PC3; HT_HG-U133A	MIIP CACNA1A CCDC28B NAB2 MAST2 NCOR2 CTNND2	8.41e-05	195	121	7	3718_DN
Drug	Amikacin hydrate [37517-28-5]; Down 200; 6.6uM; MCF7; HT_HG-U133A	MIIP LUZP1 PASK MIA2 NFATC1 SRRM2 CBX8	8.69e-05	196	121	7	3233_DN
Drug	Quinic acid [86-68-0]; Down 200; 19.6uM; PC3; HT_HG-U133A	RTEL1 PARP3 NCOR2 SBF1 NFATC1 TNS1 CDON	8.69e-05	196	121	7	7317_DN
Drug	Liothyronine [6893-02-3]; Down 200; 6.2uM; MCF7; HT_HG-U133A	NAB2 PLEKHA6 SEZ6L2 BAHD1 LUZP1 DDX54 SORBS3	8.69e-05	196	121	7	3324_DN
Drug	Probucol [23288-49-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A	MIA3 RTEL1 TNS2 PLEKHA6 MAST2 SOX13 MAP1S	8.69e-05	196	121	7	5261_DN
Drug	2-propylpentanoic acid; Down 200; 50uM; PC3; HT_HG-U133A	MIIP CCDC28B MAST2 PASK MIA2 SBF1 TNS1	8.69e-05	196	121	7	4446_DN
Drug	Diethylstilbestrol [56-53-1]; Down 200; 15uM; PC3; HT_HG-U133A	NAB2 SOX13 BAHD1 RPRD2 HSF1 TNS1 CPSF7	8.97e-05	197	121	7	4547_DN
Drug	Proxyphylline [603-00-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A	RTEL1 NLRX1 TNS2 MIA2 MEGF9 SORBS3 CDON	8.97e-05	197	121	7	5993_DN
Drug	Ethoxyquin [91-53-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A	MIIP LUZP1 MAP1S SBF1 SORBS3 TNS1 CBX8	8.97e-05	197	121	7	3846_DN
Drug	Brinzolamide [138890-62-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A	RTEL1 NLRX1 NAB2 RASSF7 CTNND2 CBX8 CDON	8.97e-05	197	121	7	3230_DN
Drug	troglitazone; Down 200; 10uM; MCF7; HT_HG-U133A_EA	DACH1 MAST2 SOX13 CCDC88C MAP1S MTCL1 CTNND2	8.97e-05	197	121	7	1012_DN
Drug	Tamoxifen citrate [54965-24-1]; Down 200; 7uM; MCF7; HT_HG-U133A	MIIP NAB2 DACH1 SBF1 SORBS3 GREB1 CBX8	8.97e-05	197	121	7	6768_DN
Drug	Pyridoxine hydrochloride [58-56-0]; Down 200; 19.4uM; MCF7; HT_HG-U133A	SOX13 RASSF7 CCDC88C NFATC1 DDX54 MTCL1 SRRM2	8.97e-05	197	121	7	7171_DN
Drug	Diperodon hydrochloride [537-12-2]; Down 200; 9.2uM; PC3; HT_HG-U133A	MIIP RASSF7 BAHD1 DDX54 SORBS3 HSF1 SRRM2	9.26e-05	198	121	7	4498_DN
Drug	Lactobionic acid [96-82-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A	NAB2 PMEL MAP1S DDX54 GREB1 ATG9A CTNND2	9.26e-05	198	121	7	3246_DN
Drug	Tolbutamide [64-77-7]; Down 200; 14.8uM; MCF7; HT_HG-U133A	MIIP TNS2 PLEKHA6 PMEL SBF1 SORBS3 CACNA1H	9.26e-05	198	121	7	2320_DN
Drug	Cinnarizine [298-57-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A	NAB2 SOX13 MAP1S CSNK1G1 SORBS3 MTCL1 GREB1	9.26e-05	198	121	7	3175_DN
Drug	vinblastine sulfate; Down 200; 0.1uM; MCF7; HT_HG-U133A	TNS2 PLEKHA6 NCOR2 SORBS3 CACNA1H VASP CBX8	9.26e-05	198	121	7	7551_DN
Drug	Flumequine [42835-25-6]; Up 200; 15.4uM; PC3; HT_HG-U133A	CCDC28B NAB2 DACH1 PMEL NCOR2 CTNND2 TNS1	9.26e-05	198	121	7	5104_UP
Drug	Ondansetron Hydrochloride [103639-04-9]; Down 200; 12.2uM; HL60; HT_HG-U133A	COL4A1 RTEL1 NAB2 TNS2 BCAN MAST2 CDON	9.26e-05	198	121	7	6153_DN
Drug	Josamycin [16846-24-5]; Down 200; 4.8uM; MCF7; HT_HG-U133A	MIIP TNS2 LUZP1 PASK SBF1 SORBS3 CBX8	9.26e-05	198	121	7	1534_DN
Drug	Hydrocotarnine hydrobromide [5985-00-2]; Down 200; 13.2uM; MCF7; HT_HG-U133A	MIIP RTEL1 NAB2 SOX13 MAP1S SORBS3 CBX8	9.26e-05	198	121	7	6827_DN
Drug	Spironolactone [52-01-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A	NLRX1 DACH1 SORBS3 MTCL1 SRRM2 SEC14L5 CDON	9.26e-05	198	121	7	2226_DN
Drug	Benzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; PC3; HT_HG-U133A	CACNA1A PARP3 TNS2 MAST2 SOX13 SBF1 TNS1	9.55e-05	199	121	7	4294_DN
Drug	SC-58125; Up 200; 10uM; MCF7; HG-U133A	CCDC28B NAB2 PMEL LUZP1 NCOR2 MEGF9 TNS1	9.55e-05	199	121	7	254_UP
Drug	Clopamide [636-54-4]; Up 200; 11.6uM; HL60; HG-U133A	MIIP CACNA1A RTEL1 BCAN LLGL2 DDX54 SORBS3	9.55e-05	199	121	7	1605_UP
Drug	Riluzole hydrochloride; Down 200; 14.8uM; PC3; HT_HG-U133A	TNS2 RASSF7 BAHD1 LUZP1 PASK SBF1 CDON	9.55e-05	199	121	7	7365_DN
Drug	Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; PC3; HT_HG-U133A	MIIP NAB2 PASK CSNK1G1 CTNND2 HSF1 PRRC2A	9.55e-05	199	121	7	3759_DN
Drug	Homochlorcyclizine dihydrochloride [1982-36-1]; Down 200; 10.4uM; PC3; HT_HG-U133A	NLRX1 TNS2 CCDC88C SBF1 SORBS3 CBX8 CDON	9.55e-05	199	121	7	7295_DN
Drug	Atracurium besylate [64228-81-5]; Down 200; 3.2uM; MCF7; HT_HG-U133A	NAB2 DACH1 TNS2 SOX13 LUZP1 MIA2 SRRM2	9.55e-05	199	121	7	1702_DN
Drug	Talampicillin hydrochloride [39878-70-1]; Down 200; 7.8uM; PC3; HT_HG-U133A	NAB2 TNS2 RASSF7 LUZP1 SORBS3 SRRM2 TNS1	9.55e-05	199	121	7	7254_DN
Drug	Iodipamide [606-17-7]; Down 200; 3.6uM; MCF7; HT_HG-U133A	MIIP MIA2 SBF1 SORBS3 MTCL1 CTNND2 PRRC2A	9.85e-05	200	121	7	5510_DN
Drug	wortmannin; Up 200; 0.01uM; SKMEL5; HG-U133A	CHST5 IL22RA1 SOX13 LUZP1 SORBS3 B3GAT1 TNS1	9.85e-05	200	121	7	506_UP
Disease	Childhood Absence Epilepsy	CACNA1A CACNA1H	3.46e-04	7	121	2	C4281785
Disease	anxiety, smoking behaviour measurement	MEGF9 UNC80	3.46e-04	7	121	2	EFO_0005230, EFO_0005671
Disease	Epilepsy, Minor	CACNA1A CACNA1H	3.46e-04	7	121	2	C4552765
Disease	Absence Epilepsy	CACNA1A CACNA1H	3.46e-04	7	121	2	C0014553
Disease	Akinetic Petit Mal	CACNA1A CACNA1H	3.46e-04	7	121	2	C0001890
Disease	Epilepsy, Absence, Atypical	CACNA1A CACNA1H	3.46e-04	7	121	2	C0751124
Disease	Absence Seizure Disorder	CACNA1A CACNA1H	3.46e-04	7	121	2	C4553705
Disease	Juvenile Absence Epilepsy	CACNA1A CACNA1H	3.46e-04	7	121	2	C4317339
Disease	cortical surface area measurement	CACNA1A TMEM8B PPFIA1 ARHGAP39 MAST2 KIAA1614 LUZP1 CCDC88C ZNF469 MTCL1 TNS1 PRRC2A TNXB RPS6KL1 WNK2	4.09e-04	1345	121	15	EFO_0010736
Disease	forced expiratory volume	NCOR2 SSC5D LLGL2 SLC2A4RG RPRD2 MTCL1 CTNND2 TNS1 TNXB CBX8 CDON	4.14e-04	789	121	11	EFO_0004314
Disease	tauopathy (implicated_via_orthology)	SH3KBP1 VASP	7.35e-04	10	121	2	DOID:680 (implicated_via_orthology)
Disease	ubiquitin-conjugating enzyme E2 G2 measurement	TNXB NOTCH4	7.35e-04	10	121	2	EFO_0022035
Disease	factor VIII measurement, coronary artery disease	COL4A1 MIA3 MAP1S PRRC2A	1.23e-03	113	121	4	EFO_0001645, EFO_0004630
Disease	extracellular matrix protein 1 measurement	MIA3 RPRD2	1.26e-03	13	121	2	EFO_0008126
Disease	brain connectivity measurement	SH3KBP1 MAST2 KIAA1614 HEXIM2 CCDC88C RPRD2 WNK2	1.34e-03	400	121	7	EFO_0005210
Disease	IGFBP-3 measurement	COL4A1 GREB1 NOTCH4	1.43e-03	54	121	3	EFO_0004626
Disease	sex interaction measurement, inflammatory bowel disease	PRRC2A TNXB NOTCH4	1.51e-03	55	121	3	EFO_0003767, EFO_0008343
Disease	endoplasmic reticulum resident protein 29 measurement	TNXB NOTCH4	1.93e-03	16	121	2	EFO_0020346
Disease	age at diagnosis, type 1 diabetes mellitus	HECW1 USP31 NOTCH4	2.13e-03	62	121	3	EFO_0004918, MONDO_0005147
Disease	body fat percentage, type 2 diabetes mellitus	KLF14 ADCY5	2.18e-03	17	121	2	EFO_0007800, MONDO_0005148
Disease	susceptibility to cold sores measurement	MUC16 CTNND2 TNXB	2.44e-03	65	121	3	EFO_0008402
Disease	X-11470 measurement	TNXB NOTCH4	2.72e-03	19	121	2	EFO_0021241
Disease	anorectal malformation	RTEL1 KLHL17	2.72e-03	19	121	2	MONDO_0019938
Disease	MHC class I polypeptide-related sequence A measurement	PRRC2A TNXB NOTCH4	2.78e-03	68	121	3	EFO_0008233
Disease	phosphatidylcholine 34:2 measurement	CACNA1A MAST2	3.02e-03	20	121	2	EFO_0010376
Disease	skin hydration measurement	PKD1L1 DTHD1	3.33e-03	21	121	2	EFO_0009586
Disease	migraine disorder	COL4A1 CACNA1A FAM47A ZBTB4 NCOR2 NOTCH4	3.61e-03	357	121	6	MONDO_0005277
Disease	prostate carcinoma	RTEL1 MAST2 SOX13 CCDC88C SLC2A4RG B3GAT1 RPS6KL1 CRAMP1 SEC14L5 NOTCH4	3.72e-03	891	121	10	EFO_0001663
Disease	serum non-albumin protein measurement	COL4A1 MIA3 MAST2 NCOR2 RPRD2 PRRC2A	3.81e-03	361	121	6	EFO_0004568
Disease	reticulocyte count	KLF14 MAST2 SPECC1 SCARF1 BLVRB ZNF469 MEGF9 KLF13 KANK3 TNS1 NOTCH4	3.85e-03	1045	121	11	EFO_0007986

Protein segments in the cluster

Peptide	Gene	Start	Entry
TRSGGPRGPRHSAPT	nan	11	Q6ZR03
HKDEGSDPRRETPPG	B3GAT1	36	Q9P2W7
APPPVRHASSGATGR	CACNA1A	2436	O00555
PHRRDSGRPPGDSSG	ARHGEF5	1006	Q12774
SDSRGPAVEKHPGPS	ARHGEF5	1051	Q12774
TPGPAHTGREAVRPD	CEACAM16	76	Q2WEN9
DSSRLPSEGPRPAHV	BLVRB	36	P30043
SVVLGHGAPRTASPP	LINC00528	66	Q8N1L1
GHGPDRVRPLPAASS	SPECC1	16	Q5M775
RAPGESGPQLARPSH	AMER1	1011	Q5JTC6
KTAAPAPRGGPEHRS	ADCY5	16	O95622
PSLEEGRRPGSHPSS	DACH1	496	Q9UI36
TTSRAGHLAGPEPAP	CTNND2	206	Q9UQB3
PPGTPSVDHGFLVTR	COL4A1	1436	P02462
APSESHAGAQPRPRG	RASSF7	331	Q02833
GPPGVRSRRPSGSQH	ARHGAP39	236	Q9C0H5
PRGGIPPRAHSRDSS	CPSF7	181	Q8N684
IGTFRSPHGQTRPPA	ECT2	711	Q9H8V3
QEREGPGRDHAPSIP	MTCL1	606	Q9Y4B5
SPPPGFDSVIARGHT	PARP3	461	Q9Y6F1
VGEDSRHAGPPVLPR	HECW2	1046	Q9P2P5
ESEASRPPRVHGPPT	BCAN	526	Q96GW7
RPEPSETGVSHLRPE	FAM47C	511	Q5HY64
AGHEPRVPTSGTGDP	MUC16	2971	Q8WXI7
AGHLPRGSPVTTREP	NCOR2	1551	Q9Y618
RESPGHVPSTLDAGP	PASK	841	Q96RG2
QLHERETPRPEGGSP	JPH2	471	Q9BR39
PRTPSPESHRSPAEG	MAP1S	636	Q66K74
RVSSRKRHPAGPPGE	LLGL2	661	Q6P1M3
EHARSPQPRGPAEEG	GREB1	1156	Q4ZG55
AGHSIGPSPVPSVVR	SLC2A7	391	Q6PXP3
APGPHPALVEGRRSS	NAB2	501	Q15742
PSGHVERSPEGLESP	HECW1	776	Q76N89
TLTPAGGHLPRPEAS	HMX3	121	A6NHT5
SLRAGPSEPHSPGRR	NFKBIE	86	O00221
RPIPTPVGSVHVDSG	CSNK1G1	331	Q9HCP0
PRRGPSPSHVRFEDE	KIAA1614	441	Q5VZ46
ASRPHAPGTPAGRVR	DDX54	806	Q8TDD1
SPGRSPDLAPHLGRA	CCDC88C	1981	Q9P219
ARGHTDTEGRPPSPP	HSF1	351	Q00613
HPAPPATAVRGRDAA	FAM157A	186	C9JC47
PAPGAREDEHVRAPS	MYOD1	71	P15172
HPPPRQGRGSFSREE	RASGRP4	506	Q8TDF6
EPGAGTPSPVRLHAL	NSUN5P2	136	Q63ZY6
HTRPDGAPALESPRI	NFATC1	106	O95644
RVPREPGVHTGSSRP	PHRF1	736	Q9P1Y6
GSGRSTPRRIPHSPA	PPFIA1	696	Q13136
GPPRATVHRPLAATS	MEGF9	81	Q9H1U4
PSAIAAGPARTPDRH	PRR25	226	Q96S07
SVDSAPPPGRHGRLF	NLRX1	56	Q86UT6
PTRDVPSGHTRDPAR	PCNT	3251	O95613
AFTLGSAHTPGRPPR	SBF1	1026	O95248
HTLAPERSVSGPLGP	FAM189B	206	P81408
EHPAPPATAVRGRDA	FAM157B	186	P0CG42
ERPAGRTQSPEHGSP	KLHL17	6	Q6TDP4
DPNGTRVRHGSGPPS	CBX8	301	Q9HC52
PAREPSLERVGGHPT	DACT3	301	Q96B18
HPGSPTRAAERVEPF	COX11	21	Q9Y6N1
GGITDPGTVPRVPSH	ATG9A	786	Q7Z3C6
RHSGVPEAPDRPTIS	CDON	716	Q4KMG0
TPAEGRDSPTREPGA	CRAMP1	526	Q96RY5
PRAHAEVDGRSTEPP	BAHD1	226	Q8TBE0
GPPEPSRHFQVREGE	DTHD1	546	Q6ZMT9
RRVGPSSGDAPEPSS	LUZP1	976	Q86V48
PSGPHRRLGSPQAIE	MAST2	1576	Q6P0Q8
PTPTPIRAGDGHRLT	IL22RA1	141	Q8N6P7
VSGPREPAGAPQRHS	IL22RA1	306	Q8N6P7
GVSHLRPEPPETGVS	FAM47A	231	Q5JRC9
ETGVSHIRPGPPITR	FAM47A	241	Q5JRC9
THERAPSPGRGVPRS	KANK3	146	Q6NY19
RAVVHGPREGPESRP	KLF13	21	Q9Y2Y9
AGAVVHRRPPDPEGA	KLF14	21	Q8TD94
REGSRLPPAREGHPV	BAG3	71	O95817
PGTLRRVPVPTSHSG	CCDC28B	21	Q9BUN5
SPGRGPPDAESVHSI	CACNA1H	561	O95180
GPPLGPSHRDTISRS	RPRD2	1396	Q5VT52
GPRDPSSLEAHGPRS	SEC14L5	196	O43304
RIGDGSPSHPPILER	SDK2	1281	Q58EX2
PGSARVEPHSPLRGG	PKD1L1	2021	Q8TDX9
PPHSEGRSEFPSGLI	MIA2	1381	Q96PC5
HRAPQPGPSRSEKTG	RTEL1	1161	Q9NZ71
RPASTSPSPGAHGRR	SRRM3	466	A6NNA2
AERHGGSPQPLATTP	SRRM2	371	Q9UQ35
RSEFGSVDGPLPHPR	MIA3	1701	Q5JRA6
QTPPERHDSGGSLPL	HEXIM2	31	Q96MH2
SHPEPQLPGLRESSG	MIIP	216	Q5JXC2
RPERPVGPLTHTRGD	SH3KBP1	421	Q96B97
PGVHPSGLVPRERSD	PRRC2A	746	P48634
TDRGTEPGPIRPSHR	PRRC2A	1741	P48634
GFPPRPAHGDVSVTD	SEZ6L2	291	Q6UXD5
TTRSPGSPPTLRVHG	SSC5D	966	A1L4H1
VPGTTDGHRPTAEAP	PMEL	306	P40967
SSRGPGRPVSSPHEL	SPTY2D1	461	Q68D10
PRARTVSVSVPPHGG	NOTCH4	1841	Q99466
ASPGDSATGHRRPPL	SCARF1	651	Q14162
RTHPTVPGIPGGTRA	ARNTL	476	O00327
RATSRPGFPPLEGSH	CSNK1G2-AS1	126	Q8NCQ2
PGPSSPAGGEDRVHV	CHST5	51	Q9GZS9
HHDGVLRPTVRPGTP	CTDNEP1	76	O95476
TPRRGPESLPVGHHD	PIK3R4	1316	Q99570
PGPGEPTLRSRQDRH	SHC4	166	Q6S5L8
ETGGHRRSFPPRTNP	PLEKHA6	291	Q9Y2H5
AAPTGPGHRALPSRD	ZFP28	61	Q8NHY6
RPPSHGGPTRDLQSS	SOX13	321	Q9UN79
RGPRPVARGPAHSSS	nan	66	P0C879
ERGPSHSRASLVIPP	UNC80	306	Q8N2C7
RIPSPGTHPEGEAAQ	ZBP1	306	Q9H171
GAAAGPRTPSAHIPV	SLC2A4RG	76	Q9NR83
PGGGSFAREPSPTHR	SHANK3	976	Q9BYB0
RSPTPVHSPDADRPG	SHANK3	1126	Q9BYB0
PRRPQPGASGRSTHT	PAPLN	811	O95428
PGHERRGTPADTEEP	PSD2	46	Q9BQI7
GKRHGPVPVEARTAP	TNXB	3336	P22105
RHRTVGTNTPPSPGF	TNS1	1181	Q9HBL0
RHAAERPGGTPTPVI	ZBTB4	786	Q9P1Z0
SGRHRLGPSPEPAAS	TMPRSS12	26	Q86WS5
QRPAHRPGPATSSSG	SORBS3	181	O60504
TPARLPSGHAPGQDR	RPS6KL1	261	Q9Y6S9
PPRAKTDHGVPSGAR	TMEM8B	426	A6NDV4
SPRVSGEEELHTGPP	PPP6R1	726	Q9UPN7
PPKRGTAVHGAEPAE	ZNF469	3876	Q96JG9
PDTPRPHRGLGATRE	ZNRF3	861	Q9ULT6
LRSEGGPPTPHRSIF	ZDHHC8	451	Q9ULC8
AHVPAATPLPERGGS	PLEKHG2	1206	Q9H7P9
SRGSGRHSSPAPAQP	USP31	1081	Q70CQ4
PVSSDSGDEGPRARP	WNK2	1841	Q9Y3S1
PVRSSARAEHGAEPP	PIGG	31	Q5H8A4
PDSTHPRGPIGLVVR	TGM7	516	Q96PF1
REGPSGHSTLPRSPR	TNS2	881	Q63HR2
EIHASLVPGPSERPG	AVPR2	231	P30518
QVLRPEGDRHSPPGT	ZNF541	886	Q9H0D2
HIERRVSNAGGPPAP	VASP	151	P50552
HGVEPGTSRRPPDTA	ZNF784	151	Q8NCA9