| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyCellularComponent | cortical actin cytoskeleton | 5.19e-05 | 93 | 46 | 4 | GO:0030864 | |
| GeneOntologyCellularComponent | cell cortex | 1.54e-04 | 371 | 46 | 6 | GO:0005938 | |
| GeneOntologyCellularComponent | cortical cytoskeleton | 1.85e-04 | 129 | 46 | 4 | GO:0030863 | |
| Domain | CEP170_C | 5.18e-06 | 2 | 43 | 2 | PF15308 | |
| Domain | CEP170_C | 5.18e-06 | 2 | 43 | 2 | IPR029300 | |
| Domain | ASD1 | 1.55e-05 | 3 | 43 | 2 | PF08688 | |
| Domain | ASD1_dom | 1.55e-05 | 3 | 43 | 2 | IPR014800 | |
| Domain | ASD1 | 1.55e-05 | 3 | 43 | 2 | PS51306 | |
| Domain | ASD2 | 3.10e-05 | 4 | 43 | 2 | PF08687 | |
| Domain | ASD2 | 3.10e-05 | 4 | 43 | 2 | PS51307 | |
| Domain | Shroom_fam | 3.10e-05 | 4 | 43 | 2 | IPR027685 | |
| Domain | ASD2_dom | 3.10e-05 | 4 | 43 | 2 | IPR014799 | |
| Domain | hEGF | 1.88e-03 | 28 | 43 | 2 | PF12661 | |
| Domain | FHA | 1.88e-03 | 28 | 43 | 2 | SM00240 | |
| Domain | FHA_DOMAIN | 2.31e-03 | 31 | 43 | 2 | PS50006 | |
| Domain | FHA | 2.31e-03 | 31 | 43 | 2 | PF00498 | |
| Domain | FHA_dom | 3.10e-03 | 36 | 43 | 2 | IPR000253 | |
| Domain | - | 3.10e-03 | 36 | 43 | 2 | 2.60.200.20 | |
| Domain | Znf_FYVE_PHD | 4.68e-03 | 147 | 43 | 3 | IPR011011 | |
| Domain | SMAD_FHA_domain | 6.38e-03 | 52 | 43 | 2 | IPR008984 | |
| Domain | LRR_6 | 7.12e-03 | 55 | 43 | 2 | PF13516 | |
| Pubmed | Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. | 1.11e-06 | 15 | 48 | 3 | 23583980 | |
| Pubmed | 1.87e-06 | 2 | 48 | 2 | 16151003 | ||
| Pubmed | 1.87e-06 | 2 | 48 | 2 | 18629938 | ||
| Pubmed | 1.87e-06 | 2 | 48 | 2 | 38579707 | ||
| Pubmed | Genetic and functional analysis of SHROOM1-4 in a Chinese neural tube defect cohort. | 1.87e-06 | 2 | 48 | 2 | 29423651 | |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | HEXA JAG2 AKAP13 SHROOM3 SPIRE2 KMT2B FHIP1B ZNF592 CEP170B NLRX1 | 2.20e-06 | 1105 | 48 | 10 | 35748872 |
| Pubmed | Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. | JAG2 CEP170 AKAP13 SHROOM3 PLXDC2 SHROOM2 WDR11 TET3 MAN1C1 CEP170B GDE1 | 4.47e-06 | 1489 | 48 | 11 | 28611215 |
| Pubmed | The role of Siglec-G on B cells in autoimmune disease and leukemia. | 5.59e-06 | 3 | 48 | 2 | 38042621 | |
| Pubmed | The ligand-binding domain of Siglec-G is crucial for its selective inhibitory function on B1 cells. | 5.59e-06 | 3 | 48 | 2 | 24790146 | |
| Pubmed | SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders. | 5.59e-06 | 3 | 48 | 2 | 24859880 | |
| Pubmed | 5.59e-06 | 3 | 48 | 2 | 17572677 | ||
| Pubmed | Copresentation of antigen and ligands of Siglec-G induces B cell tolerance independent of CD22. | 5.59e-06 | 3 | 48 | 2 | 23836061 | |
| Pubmed | 5.59e-06 | 3 | 48 | 2 | 23087211 | ||
| Pubmed | 1.08e-05 | 31 | 48 | 3 | 37573008 | ||
| Pubmed | Siglecg limits the size of B1a B cell lineage by down-regulating NFkappaB activation. | 1.12e-05 | 4 | 48 | 2 | 17912374 | |
| Pubmed | 1.12e-05 | 4 | 48 | 2 | 20038598 | ||
| Pubmed | 1.12e-05 | 4 | 48 | 2 | 20200274 | ||
| Pubmed | 1.12e-05 | 4 | 48 | 2 | 20729333 | ||
| Pubmed | Siglec-G-CD24 axis controls the severity of graft-versus-host disease in mice. | 1.12e-05 | 4 | 48 | 2 | 24695850 | |
| Pubmed | 1.12e-05 | 4 | 48 | 2 | 25252961 | ||
| Pubmed | 1.12e-05 | 4 | 48 | 2 | 30143587 | ||
| Pubmed | 1.12e-05 | 4 | 48 | 2 | 24600033 | ||
| Pubmed | A new standard nomenclature for proteins related to Apx and Shroom. | 1.12e-05 | 4 | 48 | 2 | 16615870 | |
| Pubmed | CD24 and Siglec-10 selectively repress tissue damage-induced immune responses. | 1.86e-05 | 5 | 48 | 2 | 19264983 | |
| Pubmed | Siglec-G Deficiency Leads to Autoimmunity in Aging C57BL/6 Mice. | 1.86e-05 | 5 | 48 | 2 | 25987743 | |
| Pubmed | 1.86e-05 | 5 | 48 | 2 | 32737150 | ||
| Pubmed | 1.86e-05 | 5 | 48 | 2 | 27548433 | ||
| Pubmed | 1.86e-05 | 5 | 48 | 2 | 26947073 | ||
| Pubmed | 1.86e-05 | 5 | 48 | 2 | 21602525 | ||
| Pubmed | 1.86e-05 | 5 | 48 | 2 | 36969253 | ||
| Pubmed | A hypomorphic IgH-chain allele affects development of B-cell subsets and favours receptor editing. | 1.86e-05 | 5 | 48 | 2 | 21623346 | |
| Pubmed | 2.79e-05 | 6 | 48 | 2 | 14559209 | ||
| Pubmed | 2.79e-05 | 6 | 48 | 2 | 11986327 | ||
| Pubmed | 3.90e-05 | 7 | 48 | 2 | 10079256 | ||
| Pubmed | Paired Siglec receptors generate opposite inflammatory responses to a human-specific pathogen. | 3.90e-05 | 7 | 48 | 2 | 28100677 | |
| Pubmed | The distribution of Notch receptors and their ligands during articular cartilage development. | 3.90e-05 | 7 | 48 | 2 | 12846471 | |
| Pubmed | 5.19e-05 | 8 | 48 | 2 | 9858718 | ||
| Pubmed | 6.67e-05 | 9 | 48 | 2 | 11118901 | ||
| Pubmed | 6.67e-05 | 9 | 48 | 2 | 16245338 | ||
| Pubmed | Divergent vascular mechanisms downstream of Sry establish the arterial system in the XY gonad. | 6.67e-05 | 9 | 48 | 2 | 11944948 | |
| Pubmed | 6.67e-05 | 9 | 48 | 2 | 23374343 | ||
| Pubmed | Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions. | 6.67e-05 | 9 | 48 | 2 | 17666436 | |
| Pubmed | Notch signaling is essential for vascular morphogenesis in mice. | 6.67e-05 | 9 | 48 | 2 | 10837027 | |
| Pubmed | Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta. | 8.33e-05 | 10 | 48 | 2 | 23665443 | |
| Pubmed | DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. | 8.33e-05 | 10 | 48 | 2 | 29276034 | |
| Pubmed | Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development. | 1.02e-04 | 11 | 48 | 2 | 16607638 | |
| Pubmed | 1.02e-04 | 11 | 48 | 2 | 10878608 | ||
| Pubmed | 1.02e-04 | 11 | 48 | 2 | 12866128 | ||
| Pubmed | 1.22e-04 | 12 | 48 | 2 | 15465494 | ||
| Pubmed | Collagen XIV is important for growth and structural integrity of the myocardium. | 1.22e-04 | 12 | 48 | 2 | 22906538 | |
| Pubmed | CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder. | 1.44e-04 | 13 | 48 | 2 | 35921817 | |
| Pubmed | Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels. | 1.44e-04 | 13 | 48 | 2 | 11578869 | |
| Pubmed | 1.68e-04 | 14 | 48 | 2 | 28192800 | ||
| Pubmed | 1.68e-04 | 14 | 48 | 2 | 18528438 | ||
| Pubmed | 1.68e-04 | 14 | 48 | 2 | 14757642 | ||
| Pubmed | 1.94e-04 | 15 | 48 | 2 | 12971992 | ||
| Pubmed | The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver. | 1.94e-04 | 15 | 48 | 2 | 22496360 | |
| Pubmed | Expression of Notch pathway components in fetal and adult mouse small intestine. | 2.21e-04 | 16 | 48 | 2 | 12617809 | |
| Pubmed | 2.21e-04 | 16 | 48 | 2 | 10842072 | ||
| Pubmed | Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice. | 2.21e-04 | 16 | 48 | 2 | 15037549 | |
| Pubmed | 2.21e-04 | 16 | 48 | 2 | 17273555 | ||
| Pubmed | 2.50e-04 | 17 | 48 | 2 | 18694942 | ||
| Pubmed | Segmental expression of Notch and Hairy genes in nephrogenesis. | 2.50e-04 | 17 | 48 | 2 | 15821257 | |
| Pubmed | A comprehensive family-based replication study of schizophrenia genes. | 2.50e-04 | 17 | 48 | 2 | 23894747 | |
| Pubmed | 2.81e-04 | 18 | 48 | 2 | 18093989 | ||
| Pubmed | 2.81e-04 | 18 | 48 | 2 | 19116923 | ||
| Pubmed | 2.81e-04 | 18 | 48 | 2 | 15689374 | ||
| Pubmed | 3.14e-04 | 19 | 48 | 2 | 16518823 | ||
| Pubmed | 3.85e-04 | 21 | 48 | 2 | 28656980 | ||
| Pubmed | Conversion of biliary system to pancreatic tissue in Hes1-deficient mice. | 3.85e-04 | 21 | 48 | 2 | 14702043 | |
| Pubmed | 4.63e-04 | 23 | 48 | 2 | 14701881 | ||
| Pubmed | Rbpj regulates development of prosensory cells in the mammalian inner ear. | 5.05e-04 | 24 | 48 | 2 | 21420948 | |
| Pubmed | 5.05e-04 | 24 | 48 | 2 | 15331780 | ||
| Pubmed | Proteomic characterization of the human centrosome by protein correlation profiling. | 5.93e-04 | 26 | 48 | 2 | 14654843 | |
| Pubmed | Notch signaling controls liver development by regulating biliary differentiation. | 5.93e-04 | 26 | 48 | 2 | 19369401 | |
| Pubmed | 7.39e-04 | 29 | 48 | 2 | 24971735 | ||
| Pubmed | 7.39e-04 | 29 | 48 | 2 | 24909139 | ||
| Pubmed | 7.39e-04 | 29 | 48 | 2 | 25535917 | ||
| Pubmed | Notch signaling in stomach epithelial stem cell homeostasis. | 7.39e-04 | 29 | 48 | 2 | 21402740 | |
| Pubmed | Notch signaling regulates ovarian follicle formation and coordinates follicular growth. | 7.92e-04 | 30 | 48 | 2 | 24552588 | |
| Pubmed | Comparative interactome analysis of α-arrestin families in human and Drosophila. | 9.17e-04 | 313 | 48 | 4 | 38270169 | |
| Pubmed | 1.02e-03 | 34 | 48 | 2 | 21311046 | ||
| Pubmed | A genome-wide association study (GWAS) for bronchopulmonary dysplasia. | 1.02e-03 | 34 | 48 | 2 | 23897914 | |
| Pubmed | Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. | 1.08e-03 | 35 | 48 | 2 | 21252157 | |
| Pubmed | 1.10e-03 | 329 | 48 | 4 | 17474147 | ||
| Pubmed | 1.20e-03 | 37 | 48 | 2 | 24673559 | ||
| Pubmed | 1.20e-03 | 37 | 48 | 2 | 27631609 | ||
| Pubmed | 1.31e-03 | 591 | 48 | 5 | 15231748 | ||
| Cytoband | Ensembl 112 genes in cytogenetic band chr15q25 | 6.40e-04 | 160 | 48 | 3 | chr15q25 | |
| GeneFamily | Zinc fingers CXXC-type | 1.51e-04 | 12 | 28 | 2 | 136 | |
| GeneFamily | CD molecules|C2-set domain containing|Sialic acid binding Ig like lectins | 8.53e-04 | 28 | 28 | 2 | 745 | |
| GeneFamily | C2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors | 1.74e-03 | 40 | 28 | 2 | 592 | |
| GeneFamily | Endogenous ligands|Minor histocompatibility antigens | 2.81e-03 | 51 | 28 | 2 | 870 | |
| GeneFamily | PHD finger proteins | 8.52e-03 | 90 | 28 | 2 | 88 | |
| Coexpression | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_UP | 1.80e-05 | 181 | 47 | 5 | M8579 | |
| Coexpression | GSE40443_INDUCED_VS_TOTAL_TREG_UP | 2.84e-05 | 199 | 47 | 5 | M9198 | |
| Coexpression | GSE3039_NKT_CELL_VS_ALPHABETA_CD8_TCELL_UP | 2.91e-05 | 200 | 47 | 5 | M6429 | |
| ToppCell | Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type | 4.29e-08 | 186 | 47 | 6 | 23b8d51d20b05795a73892d3e20e0f9b6a207820 | |
| Computational | Genes in the cancer module 175. | 2.25e-04 | 54 | 24 | 3 | MODULE_175 | |
| Computational | Genes in the cancer module 120. | 5.06e-04 | 71 | 24 | 3 | MODULE_120 | |
| Disease | chronic kidney disease (implicated_via_orthology) | 1.62e-04 | 12 | 47 | 2 | DOID:784 (implicated_via_orthology) | |
| Disease | interstitial lung disease | 1.69e-04 | 67 | 47 | 3 | EFO_0004244 | |
| Disease | X-11470 measurement | 4.17e-04 | 19 | 47 | 2 | EFO_0021241 | |
| Disease | Carcinoma, Pancreatic Ductal | 6.70e-04 | 24 | 47 | 2 | C0887833 | |
| Disease | breast cancer, lung cancer | 7.28e-04 | 25 | 47 | 2 | MONDO_0007254, MONDO_0008903 | |
| Disease | eosinophil percentage of leukocytes | 1.14e-03 | 746 | 47 | 6 | EFO_0007991 | |
| Disease | lower urinary tract symptom, benign prostatic hyperplasia | 1.19e-03 | 32 | 47 | 2 | EFO_0000284, EFO_0008008 | |
| Disease | thyroid carcinoma | 1.77e-03 | 39 | 47 | 2 | EFO_0002892 | |
| Disease | bronchopulmonary dysplasia | 2.35e-03 | 45 | 47 | 2 | MONDO_0019091 | |
| Disease | serum albumin measurement | 2.45e-03 | 592 | 47 | 5 | EFO_0004535 | |
| Disease | rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement | 2.53e-03 | 170 | 47 | 3 | EFO_0000685, EFO_0007791, EFO_0007837 | |
| Disease | hair colour measurement | 2.88e-03 | 615 | 47 | 5 | EFO_0007822 | |
| Disease | retinal drusen | 3.01e-03 | 51 | 47 | 2 | EFO_1001155 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| LGRHLGRWSPSSVPS | 176 | Q8N715 | |
| WFLVSSGGTRHRLPR | 6 | Q5SW79 | |
| WASRSLHPLPGSRDR | 21 | Q4G0I0 | |
| RSLSPFRRHSWGPGK | 1556 | Q12802 | |
| TWKGPERLAHGSPFR | 696 | O94983 | |
| WKGGRSHPFLPHSSR | 116 | Q8IVW1 | |
| PWRTAERAKRHRGFP | 391 | Q5JTW2 | |
| IRRGHRPRGSLDWPS | 1031 | Q9Y4F5 | |
| GDRWVSRPRGHFSPA | 16 | Q9GZT6 | |
| KRTRTGRSWPAAIPH | 481 | Q9Y483 | |
| FTWKGHERLSPRTGP | 566 | Q15334 | |
| WLSRLASRGPGHRIP | 6 | Q8N612 | |
| FTKDPGRSPGRPAHW | 1201 | Q9Y219 | |
| PRPKGRNRSHDWSSL | 1116 | Q14999 | |
| GTFSWPLAARGKPRR | 166 | A6NMT0 | |
| GWGRPRSFPRAPTVH | 21 | Q9C075 | |
| KRRWATRGPAHPAFA | 161 | P13985 | |
| GPSYPTRATRKRRHW | 1281 | Q9UMN6 | |
| HDPKYWRRSTRLPNG | 1511 | Q9UMN6 | |
| QWARRLSRKGPKHSG | 1016 | Q6UVM3 | |
| HLPRASWGSGFRRAL | 6 | Q86UT6 | |
| SPRKGWSFMHPGRLT | 701 | O00469 | |
| HRPWSLSHTGDGKPR | 226 | Q9NZC3 | |
| GQRWRLGDPRSHPKL | 331 | P36269 | |
| PSSWASPRRRKGGLR | 96 | Q9NR34 | |
| GVTAGRPRPTARHWF | 111 | P28300 | |
| GSWPRPYLTGKRHTL | 76 | P06865 | |
| RKARRDARGPYHWSP | 406 | Q504T8 | |
| PPFWGLRHSRGLPRF | 11 | Q5ST30 | |
| GSRKAHVRWEAPFRP | 2341 | O75445 | |
| RWPAMKFRRGSGHPA | 496 | Q6UX71 | |
| TDRPWRSAHPGSLGK | 366 | Q13796 | |
| SWRPRPSSAHVGLRS | 956 | Q8TF72 | |
| REHGALWLPPGFTRR | 1476 | Q99466 | |
| RPGPLKRSLHSWGSD | 211 | Q96KW2 | |
| RGPGRSRTKRWPFGK | 311 | Q15642 | |
| SRSHSRGREGLRPPW | 41 | Q5M9Q1 | |
| FPHLFTGKRTPWRGI | 156 | O75351 | |
| RPSRRGYSSHHGPSW | 56 | Q8IXZ2 | |
| ESGPGWLHKARRPTR | 86 | Q8NBB2 | |
| RPRAGSAHVWRPGSR | 471 | Q8WWL2 | |
| SSLPSGRWGRPEAHR | 956 | Q92610 | |
| ASHSGGRLRGKPWSP | 1501 | O43151 | |
| KPSLSYHQRFGRPRW | 366 | E7ETH6 | |
| PTHRSWVRKIRFAPG | 746 | Q9BZH6 | |
| FSWTGAALSPRRTRP | 191 | Q96RL6 | |
| WAHPGRTRGPSDRGF | 256 | O14746 | |
| RVLSSSHPWGPRTLG | 276 | A6NMB1 | |
| RLRWKLFSHPSPSTG | 16 | Q9NR64 | |
| WARGSRPRHASLPSS | 1071 | Q14957 |