Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

NCOA2 ASXL1 NCOR1 VDR

1.48e-0455974GO:0042974
GeneOntologyMolecularFunctionnuclear retinoid X receptor binding

NCOA2 NCOR1 VDR

1.83e-0423973GO:0046965
GeneOntologyMolecularFunctionnuclear receptor binding

NCOA2 ASXL1 JMJD1C NCOR1 PKN1 VDR

3.04e-04187976GO:0016922
HumanPhenoAbnormal basophil morphology

TET2 ASXL1 BCR

1.01e-058303HP:0001912
PathwayREACTOME_CDC42_GTPASE_CYCLE

ARHGEF12 LBR GMIP BCR PLEKHG1 DOCK6

9.62e-0694746MM15598
PathwayREACTOME_CDC42_GTPASE_CYCLE

ARHGEF12 LBR GMIP BCR PLEKHG1 DOCK6 WIPF2

1.65e-05155747M41808
PathwayREACTOME_RHO_GTPASE_CYCLE

ARHGEF12 LBR GMIP BCR PLEKHG1 ARHGAP6 ELMO2 PKN1 DOCK6 WIPF2 CPSF7

2.11e-054507411M27078
PathwayREACTOME_RAC1_GTPASE_CYCLE

LBR GMIP BCR PLEKHG1 PKN1 DOCK6 WIPF2

4.96e-05184747M41809
PathwayREACTOME_RHO_GTPASE_CYCLE

ARHGEF12 LBR GMIP BCR PLEKHG1 ARHGAP6 ELMO2 PKN1 DOCK6 CPSF7

9.35e-054397410MM15595
PathwayREACTOME_RHOA_GTPASE_CYCLE

ARHGEF12 LBR GMIP BCR ARHGAP6 PKN1

9.92e-05142746MM15576
PathwayREACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS

BCAN CHPF2 CHST7

1.27e-0419743MM14800
PathwayREACTOME_RHOA_GTPASE_CYCLE

ARHGEF12 LBR GMIP BCR ARHGAP6 PKN1

1.29e-04149746M41805
PathwayREACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS

BCAN CHPF2 CHST7

1.48e-0420743M658
PathwayREACTOME_RAC1_GTPASE_CYCLE

LBR GMIP BCR PLEKHG1 PKN1 DOCK6

3.09e-04175746MM15599
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

NCOA2 ARHGEF12 LBR GMIP BCR PLEKHG1 ARHGAP6 ELMO2 PKN1 DOCK6 WIPF2 CPSF7

3.41e-047207412M41838
PathwayREACTOME_RHOC_GTPASE_CYCLE

ARHGEF12 LBR BCR PKN1

4.94e-0470744MM15597
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

NCOA2 ARHGEF12 LBR GMIP BCR PLEKHG1 ARHGAP6 ELMO2 PKN1 DOCK6 CPSF7

5.37e-046497411MM15690
PathwayREACTOME_RHOC_GTPASE_CYCLE

ARHGEF12 LBR BCR PKN1

6.10e-0474744M41807
PathwayKEGG_MEDICUS_REFERENCE_CHONDROITIN_SULFATE_BIOSYNTHESIS

CHPF2 CHST7

7.46e-048742M47920
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PER1 FRMD8 BCR ATP13A2 ACOX3 C6orf132 PPP1R26 PLEKHG1 NCOR1 TRAPPC12 BTBD7 ZFYVE26 PKN1 MICAL3 TNFAIP2 DOCK6 ALKBH6 FEM1A TJP3

4.92e-1011051021935748872
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ASXL1 TCF20 FRMPD1 ARHGEF12 USP19 RNF157 PLEKHG1 BTBD7 CHPF2 MICAL3

3.53e-074071021012693553
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

NCOA2 TET2 TCF20 BCL7B UBN2 JMJD1C NCOR1 CPSF7

1.31e-06268102833640491
Pubmed

Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo.

TET2 ASXL1

8.52e-062102224218140
Pubmed

Prognostic interaction between ASXL1 and TET2 mutations in chronic myelomonocytic leukemia.

TET2 ASXL1

8.52e-062102226771811
Pubmed

Spectrum of mutations in RARS-T patients includes TET2 and ASXL1 mutations.

TET2 ASXL1

8.52e-062102220334914
Pubmed

Analysis of core mutation and TET2/ASXL1 mutations DNA methylation profile in myelodysplastic syndrome.

TET2 ASXL1

8.52e-062102237288803
Pubmed

TET2 rs2454206, TET2 rs12498609 and ASXL1 rs3746609 single nucleotide polymorphisms in patients with myelodysplastic syndromes.

TET2 ASXL1

8.52e-062102230454965
Pubmed

Role of TET2 and ASXL1 mutations in the pathogenesis of myeloproliferative neoplasms.

TET2 ASXL1

8.52e-062102223009937
Pubmed

Mutations of ASXL1 and TET2 in aplastic anemia.

TET2 ASXL1

8.52e-062102225596262
Pubmed

Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex.

TET2 ASXL1

8.52e-062102226095772
Pubmed

ASXL1 but not TET2 mutations adversely impact overall survival of patients suffering systemic mastocytosis with associated clonal hematologic non-mast-cell diseases.

TET2 ASXL1

8.52e-062102224465546
Pubmed

The prognostic value of the interaction between ASXL1 and TET2 gene mutations in patients with chronic myelomonocytic leukemia: a meta-analysis.

TET2 ASXL1

8.52e-062102235306971
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TET2 TCF20 CAMSAP3 PARD3B LBR BCR C6orf132 PLEKHG1 HAUS8 ELMO2 DOCK6 PPP1R12C

8.63e-068611021236931259
Pubmed

Interaction network of human early embryonic transcription factors.

NCOA2 TET2 TCF20 ACACB BCL7B UBN2 SOX13 NCOR1

9.56e-06351102838297188
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

TCF20 ACACB LBR JMJD1C NCOR1 CPSF7

1.58e-05180102635198878
Pubmed

Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease.

SH3BP2 BCR PPP1R12C

1.62e-0517102322153077
Pubmed

Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.

BCL7B BUD13 LIPC DOCK6

1.97e-0554102423505323
Pubmed

Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure.

TET2 ASXL1

2.55e-053102234210413
Pubmed

Involvement of SMRT corepressor in transcriptional repression by the vitamin D receptor.

NCOR1 VDR

2.55e-053102219098224
Pubmed

TET2, ASXL1 and EZH2 mutations in Chinese with myelodysplastic syndromes.

TET2 ASXL1

2.55e-053102223099237
Pubmed

Contributions of the RhoGEF activity of p210 BCR/ABL to disease progression.

ARHGEF12 BCR

2.55e-053102223207522
Pubmed

Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation.

NCOA2 VDR

2.55e-053102219052561
Pubmed

[Relationship between DTA Mutations and Thromboembolism in Patients with Myeloproliferative Neoplasms].

TET2 ASXL1

2.55e-053102238926973
Pubmed

Epigenetic Changes in Neoplastic Mast Cells and Potential Impact in Mastocytosis.

TET2 ASXL1

2.55e-053102233803981
Pubmed

Mutations of ASXL1 gene in myeloproliferative neoplasms.

TET2 ASXL1

2.55e-053102219609284
Pubmed

Clonal haematopoiesis of indeterminate potential and atrial fibrillation: an east Asian cohort study.

TET2 ASXL1

2.55e-053102238231881
Pubmed

Antagonistic action of a 25-carboxylic ester analogue of 1alpha, 25-dihydroxyvitamin D3 is mediated by a lack of ligand-induced vitamin D receptor interaction with coactivators.

NCOA2 VDR

2.55e-053102210748178
Pubmed

Telomere Attrition and Clonal Hematopoiesis of Indeterminate Potential in Cardiovascular Disease.

TET2 ASXL1

2.55e-053102234576030
Pubmed

Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors.

NCOA2 NCOR1

2.55e-053102224550004
Pubmed

Mutation analysis of ASXL1, CBL, DNMT3A, IDH1, IDH2, JAK2, MPL, NF1, SF3B1, SUZ12, and TET2 in myeloproliferative neoplasms.

TET2 ASXL1

2.55e-053102222489043
Pubmed

Finding underlying genetic mechanisms of two patients with autism spectrum disorder carrying familial apparently balanced chromosomal translocations.

JMJD1C DDX11

2.55e-053102233591602
Pubmed

Measurable residual disease of canonical versus non-canonical DNMT3A, TET2, or ASXL1 mutations in AML at stem cell transplantation.

TET2 ASXL1

2.55e-053102234267355
Pubmed

HIV is associated with an increased risk of age-related clonal hematopoiesis among older adults.

TET2 ASXL1

2.55e-053102234099923
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

NCOA2 SH3BP2 FRMPD1 CAMSAP3 PARD3B UBN2 BCR JMJD1C ARHGAP6 GPR158 PKN1 MICAL3 IGSF9B DOCK6 UBE2E3

2.92e-0514891021528611215
Pubmed

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

NCOA2 JMJD1C NCOR1

3.13e-0521102319596656
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

ATG4A TCF20 JMJD1C NCOR1 ELF4

3.23e-05123102526912792
Pubmed

Molecular similarity between myelodysplastic form of chronic myelomonocytic leukemia and refractory anemia with ring sideroblasts.

TET2 ASXL1

5.09e-054102223065512
Pubmed

Mutations and karyotype predict treatment response in myelodysplastic syndromes.

TET2 ASXL1

5.09e-054102230152885
Pubmed

Oxyntomodulin regulates resetting of the liver circadian clock by food.

PER1 GCG

5.09e-054102225821984
Pubmed

Agonist-triggered modulation of the activated and silent state of the vitamin D(3) receptor by interaction with co-repressors and co-activators.

NCOR1 VDR

5.09e-054102211124027
Pubmed

Vitamin D-dependent recruitment of corepressors to vitamin D/retinoid X receptor heterodimers.

NCOR1 VDR

5.09e-054102218362166
Pubmed

TET2, ASXL1, IDH1, and IDH2 Single Nucleotide Polymorphisms in Turkish Patients with Chronic Myeloproliferative Neoplasms.

TET2 ASXL1

5.09e-054102228218607
Pubmed

Retinoid X receptor is a nonsilent major contributor to vitamin D receptor-mediated transcriptional activation.

NCOA2 VDR

5.09e-054102212893883
Pubmed

VDR-Alien: a novel, DNA-selective vitamin D(3) receptor-corepressor partnership.

NCOR1 VDR

5.09e-054102210877839
Pubmed

Single nucleotide polymorphism array lesions, TET2, DNMT3A, ASXL1 and CBL mutations are present in systemic mastocytosis.

TET2 ASXL1

5.09e-054102222905207
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

SH3BP2 PER1 MARCHF7 PYM1 GMIP BCR SOX13 HAUS8 PDE8B BTBD7 DOCK6 TJP3

5.38e-0510381021226673895
Pubmed

GLIS3 expression in the thyroid gland in relation to TSH signaling and regulation of gene expression.

GLIS3 GCG CDH16

6.06e-0526102338281222
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

NCOA2 TCF20 GLIS3 LBR JMJD1C NCOR1 RAB34 CPSF7

6.24e-05457102832344865
Pubmed

Human transcription factor protein interaction networks.

NCOA2 TET2 ASXL1 TCF20 ACACB BCL7B LBR UBN2 SOX13 JMJD1C NCOR1 ELF4 CPEB1 CPSF7

7.43e-0514291021435140242
Pubmed

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.

NCOA2 TCF20 JMJD1C NCOR1

8.42e-0578102428611094
Pubmed

Cooperating gene mutations in childhood acute myeloid leukemia with special reference on mutations of ASXL1, TET2, IDH1, IDH2, and DNMT3A.

TET2 ASXL1

8.47e-055102223365461
Pubmed

Epigenetic control of a VDR-governed feed-forward loop that regulates p21(waf1/cip1) expression and function in non-malignant prostate cells.

NCOR1 VDR

8.47e-055102221088000
Pubmed

Frequent somatic mutations in epigenetic regulators in newly diagnosed chronic myeloid leukemia.

TET2 ASXL1

8.47e-055102228452984
Pubmed

Calmodulin-dependent kinase IV stimulates vitamin D receptor-mediated transcription.

NCOA2 VDR

8.47e-055102215919723
Pubmed

Ternary complexes and cooperative interplay between NCoA-62/Ski-interacting protein and steroid receptor coactivators in vitamin D receptor-mediated transcription.

NCOA2 VDR

8.47e-055102211514567
Pubmed

Antiandrogen effects of mifepristone on coactivator and corepressor interactions with the androgen receptor.

NCOA2 NCOR1

8.47e-055102214593076
Pubmed

TET2, ASXL1, IDH1, IDH2, and c-CBL genes in JAK2- and MPL-negative myeloproliferative neoplasms.

TET2 ASXL1

8.47e-055102221904853
Pubmed

Function of multiple Lis-Homology domain/WD-40 repeat-containing proteins in feed-forward transcriptional repression by silencing mediator for retinoic and thyroid receptor/nuclear receptor corepressor complexes.

NCOR1 UBE2E3

8.47e-055102218202150
Pubmed

Genetics of the myeloproliferative neoplasms.

TET2 ASXL1

8.47e-055102221307773
Pubmed

2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 potently stimulates gene-specific DNA binding of the vitamin D receptor in osteoblasts.

NCOA2 VDR

8.47e-055102212796488
Pubmed

Coactivator and corepressor gene expression in rat cerebellum during postnatal development and the effect of altered thyroid status.

NCOA2 NCOR1

8.47e-055102210803578
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

JMJD1C HECW2 CHPF2 MICAL3 DOCK6

9.12e-05153102510718198
Pubmed

Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro.

ISM1 MYOCD CHST7

9.39e-0530102329555813
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

CAMSAP3 ARHGEF12 BCR DDX11 PLEKHG1 HAUS8

1.00e-04251102629778605
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

NCOA2 TCF20 JMJD1C NCOR1

1.07e-0483102428794006
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

NCOA2 GLIS3 PER1 JMJD1C USP19 TNFAIP2 FEM1A

1.15e-04371102715747579
Pubmed

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.

BCL7B BUD13 LIPC

1.25e-0433102318193044
Pubmed

A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma-coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro.

NCOA2 NCOR1

1.27e-046102216373399
Pubmed

Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway.

FRMD8 F8

1.27e-046102229776906
Pubmed

Polyamines modulate the interaction between nuclear receptors and vitamin D receptor-interacting protein 205.

NCOA2 VDR

1.27e-046102212089346
Pubmed

CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia.

TET2 ASXL1

1.27e-046102221346257
Pubmed

Differential Gene Dosage Effects of Diabetes-Associated Gene GLIS3 in Pancreatic β Cell Differentiation and Function.

GLIS3 GCG

1.27e-046102227813676
Pubmed

The interaction of the vitamin D receptor with nuclear receptor corepressors and coactivators.

NCOR1 VDR

1.27e-04610229878542
Pubmed

AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor.

NCOR1 VDR

1.27e-046102212460926
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

CAMSAP3 ELP1 GMIP BCR JMJD1C ELMO2 CHPF2 MICAL3 TNFAIP2

1.29e-04650102938777146
Pubmed

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings.

NCOA2 VDR

1.77e-047102221478865
Pubmed

An additional region of coactivator GRIP1 required for interaction with the hormone-binding domains of a subset of nuclear receptors.

NCOA2 VDR

1.77e-04710229920895
Pubmed

Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor.

ASXL1 NCOR1

1.77e-047102216606617
Pubmed

Biosynthesis of chondroitin sulphate by a Golgi-apparatus-enriched preparation from cultures of mouse mastocytoma cells.

CHPF2 CHST7

2.36e-04810226781479
Pubmed

Identification of a novel lncRNA (G3R1) regulated by GLIS3 in pancreatic β-cells.

GLIS3 GCG

2.36e-048102232668405
Pubmed

Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors.

NCOR1 VDR

2.36e-04810229121466
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TET2 TCF20 ACACB CAMSAP3 BCR JMJD1C NCOR1

2.39e-04418102734709266
Pubmed

Structural determinants of the agonist-independent association of human peroxisome proliferator-activated receptors with coactivators.

NCOA2 VDR

3.03e-049102215888456
Pubmed

Cross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factors.

NCOR1 VDR

3.03e-049102211891224
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

NCOA2 ELP1 UBN2 BCR SOX13 DDX11 NCOR1 CPSF7

3.47e-04588102838580884
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

CAMSAP3 ARHGEF12 LBR GMIP BCR PLEKHG1 ARHGAP6 ELMO2 DOCK6 WIPF2

3.67e-049161021032203420
Pubmed

Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene.

GLIS3 GCG

3.77e-0410102233852861
Pubmed

Transcriptional cofactors exhibit differential preference toward peroxisome proliferator-activated receptors alpha and delta in uterine cells.

NCOA2 NCOR1

3.77e-0410102215001550
Pubmed

Genetic variants influencing circulating lipid levels and risk of coronary artery disease.

BCL7B BUD13 LIPC

4.09e-0449102320864672
Pubmed

The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome.

NCOA2 JMJD1C

4.60e-0411102236613751
Pubmed

Prognostic implications of genetic variants in advanced non-small cell lung cancer: a genome-wide association study.

NCOA2 LIPC

4.60e-0411102223144319
Pubmed

Electrostatic modulation in steroid receptor recruitment of LXXLL and FXXLF motifs.

NCOA2 VDR

4.60e-0411102212612084
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TCF20 CAMSAP3 BUD13 USP19 NCOR1 USP42 PKN1 MICAL3 UBE2E3

4.64e-04774102915302935
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NCOA2 TCF20 NHSL2 CAMSAP3 ARHGEF12 UBN2 BCR NCOR1 GPR158 PKN1

5.41e-049631021028671696
Pubmed

Combined mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 and WT1 genes in myelodysplastic syndromes and acute myeloid leukemias.

TET2 ASXL1

5.51e-0412102220678218
Pubmed

ASXL1 mutation is associated with poor prognosis and acute transformation in chronic myelomonocytic leukaemia.

TET2 ASXL1

6.50e-0413102220880116
Pubmed

Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk.

NCOA2 VDR

6.50e-0413102219255064
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

ARHGEF12 BUD13 LBR JMJD1C DNAH6 CPSF7

7.00e-04361102626167880
Pubmed

Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase.

BCR GJD4 ARHGAP6

7.42e-0460102322889411
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

CAMSAP3 PPP1R26 NCOR1 PPP1R12C VDR

6.37e-04181695694
CoexpressionGSE32128_INOS_DEPENDENT_VS_INOS_INDEPENDENT_ACTIVATED_TCELL_DN

NCOA2 SH3BP2 GMIP HAUS8 LIPC INSM2 CPSF7 TJP3

1.10e-062001018M8602
CoexpressionGSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TCONV_UP

GCG ACOX3 ARHGAP6 TRAPPC12 LPIN2 ELF4 PPP1R12C

1.23e-051991017M8964
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

FRMD8 MARCHF7 BCR TRAPPC12 ELF4 ZNF415

2.16e-061641026d2218d50e0e2d19f919dcb460b3840687c082810
ToppCellfacs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDF10 PLEKHG1 FNDC1 RAB34 C1QTNF12 VDR

2.40e-06167102678909f685ccd1321064eb0887caf9263e0e54879
ToppCellCOVID-19-kidney-PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

DUSP6 FRMD8 F8 JMJD1C PLEKHG1 DOCK6

3.69e-061801026493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SH3BP2 GLIS3 PARD3B SOX13 RAB34

5.04e-06190102678cc6c28b31de041c24175a98f47da256ecc15a2
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SH3BP2 GLIS3 PARD3B SOX13 RAB34

5.04e-061901026e67d9400467b438592690b23d681e6c2fb8f09fd
ToppCellfacs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISM1 CAMSAP3 GDF10 ATP13A2 C1QTNF12 VDR

5.51e-061931026eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCellfacs-Skin-Anagen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISM1 CAMSAP3 GDF10 ATP13A2 C1QTNF12 VDR

5.68e-0619410265d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-Migrating_MyoFibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

GDF10 FNDC1 GPR158 MYOCD DOCK6

2.89e-0515510251882fa5fd25f77d6e3ac47b613f6fb3c67d8e50c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ELP1 HAUS8 MYOCD ALKBH6 FEM1A

3.58e-051621025502ed67f6a572f10ac6e22948a1747d8214eb974
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ELP1 HAUS8 MYOCD ALKBH6 FEM1A

3.58e-05162102582e782096f89cd03d1fdf599ba727d6f23e35e2d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ELP1 HAUS8 MYOCD ALKBH6 FEM1A

3.58e-0516210256bed33b17b59812646dc6a29c1d87413bad86c11
ToppCellRSV-Healthy-6|Healthy / Virus stimulation, Condition and Cluster

TCF20 LINC01547 BRME1 PPP1R26 C1QTNF12

3.79e-0516410251b9c5a6dc4e09b90f92e98b81a5ee620f8479cc7
ToppCellRSV-Healthy-6|RSV / Virus stimulation, Condition and Cluster

TCF20 LINC01547 BRME1 PPP1R26 C1QTNF12

3.79e-051641025ab312b8c2f828ea7331f2a340c4df81587a23b5c
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLIS3 RASSF10 GCG BCR MICAL3

3.79e-051641025d6f71d804bb65301c02ea4e6673e20688b5fcd5b
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3BP2 PER1 BRME1 C6orf132 RAB34

4.25e-0516810252e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCell356C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ATG4A NCOA2 SDHAF1 SESN2 CHST7

4.37e-0516910250425d2580ed325178f522c0093ff4623de6ce7a8
ToppCell356C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ATG4A NCOA2 SDHAF1 SESN2 CHST7

4.37e-051691025fec669968a77060bd77ee8695034e35a642c984f
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZNF696 PDE8B ELF4 DNAH6 CPEB1

4.76e-051721025c6bc78fd63c9479a84ec0552b55c89750cad0fa5
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZNF696 PDE8B ELF4 DNAH6 CPEB1

4.76e-051721025bfb87a281a9cf6ad45b310bf8104fc0ab382b549
ToppCell356C-Lymphocytic-NK_cells-NK_cell_B1|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

UBN2 PLEKHG1 C1QTNF12 DOCK6

5.02e-058810241ca0e16981e88030987412e12838a9797b97b9c9
ToppCellfacs-Skin-Anagen-24m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISM1 GDF10 GJD4 RAB34 C1QTNF12

5.16e-0517510255552ff1e13f931c8cd7780726c90b5609497a648
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)|343B / Donor, Lineage, Cell class and subclass (all cells)

ISM1 ZNF696 GDF10 PDE8B CPEB1

5.45e-051771025e55d21d4d61a069b9bbe0e7595fbfb7cfbacfd87
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-|343B / Donor, Lineage, Cell class and subclass (all cells)

ISM1 ZNF696 GDF10 PDE8B CPEB1

5.45e-05177102543ba6f12c2fb32698a420bf799d46ac1b558f146
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ISM1 ARHGAP6 GPR158 PDE8B DOCK6

5.60e-051781025185b44700f06ec58b3c09c80520502166c965fd6
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARD3B F8 PLEKHG1 HECW2 DOCK6

5.90e-051801025dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARD3B F8 PLEKHG1 HECW2 DOCK6

5.90e-051801025423454e3390080ae03bb3cbb267255ebfe4df080
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAP43 NHSL2 BCR FAM229A DOCK6

6.06e-051811025cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARD3B F8 PLEKHG1 BTBD7 HECW2

6.06e-051811025a53f05c4c47465ee62e353716456bd09ab464b23
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAP43 FRMPD1 ISM1 BCR PDE8B

6.22e-0518210259edaccf1154cec92ca9a28e9b1f9075cfd422bfd
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAP43 FRMPD1 ISM1 BCR PDE8B

6.22e-051821025aba4c06d5d7618ac21b2695bca8e7a1346a91090
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDF10 FNDC1 RAB34 ELMO2 WIPF2

6.55e-0518410256b0c110d8930df99043c3b99cf4d873985126960
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDF10 FNDC1 RAB34 ELMO2 WIPF2

6.55e-05184102535928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCellPBMC-Control-cDC_10|Control / Compartment, Disease Groups and Clusters

CASP7 PLEKHG1 CHST7 CPEB1 TJP3

6.72e-0518510254b5a7450fed912f340da16065c1e65d626dbe8d1
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA2 BUD13 PARD3B F8 HECW2

6.89e-05186102537860daeecd6d412bd3797f30496a56da667fbd1
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA2 BUD13 PARD3B F8 HECW2

6.89e-05186102560830822d3de3147816693404fd03392e04c2b8e
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA2 BUD13 PARD3B F8 HECW2

6.89e-051861025baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SH3BP2 GLIS3 PARD3B RAB34

7.07e-051871025dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SH3BP2 GLIS3 PARD3B RAB34

7.07e-0518710254d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SH3BP2 GLIS3 PARD3B RAB34

7.07e-051871025ae90c263f80c36a410150d499e268d198944a3d9
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB GLIS3 RASSF10 PARD3B RAB34

7.07e-0518710252b1b2c3792d6c9ab69675ce88842bb589414b530
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ACACB ELP1 PARD3B PLEKHG1 LIPC

7.07e-051871025f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

F8 PLEKHG1 HECW2 MICAL3 DOCK6

7.25e-051881025c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

F8 PLEKHG1 HECW2 MICAL3 DOCK6

7.25e-051881025aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TET2 DUSP6 JMJD1C TNFAIP2 VDR

7.43e-05189102555aba1ebc012006a5db3ff9c92589cb3d9f7c68a
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGEF12 BCR PLEKHG1 HECW2 DOCK6

7.62e-0519010250e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel|Adult / Lineage, Cell type, age group and donor

F8 PLEKHG1 HECW2 MICAL3 DOCK6

7.62e-05190102591bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GAP43 ISM1 PDE8B SESN2 CPEB1

7.62e-0519010257fec459cd2ad12c2923a03d098289337c0a4c1d3
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GDF10 FNDC1 RAB34 PRCD CPEB1

8.00e-051921025c3707243c5590d852c9f28429c96f50a1fa6b0dc
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SH3BP2 GLIS3 PARD3B RAB34

8.00e-05192102543beaac1de99b9c1a6dab4a450b4e81286987b64
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARD3B F8 PLEKHG1 HECW2 DOCK6

8.20e-051931025826b8dd801298b3e0cd76232feae5a14026b8806
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARD3B F8 PLEKHG1 HECW2 DOCK6

8.20e-05193102587d3a577d37fb0cb4b6313c596310de452bc3872
ToppCellFetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGEF12 PLEKHG1 HECW2 RP1L1 DOCK6

8.20e-051931025ad2df9b77999780860141be6ec366afc0172a331
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARD3B F8 PLEKHG1 HECW2 DOCK6

8.20e-051931025d485634c564b268e344b6a2863c26f6adaec9e38
ToppCell356C-Lymphocytic-NK_cells-NK_cell_B1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

UBN2 C6orf132 C1QTNF12 DOCK6

8.26e-051001024cb0deaf1c33d2789417e93cc01d94e34a611d20a
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF12 GCG ATP13A2 SOX13 HECW2

8.40e-051941025f159ef8541d75a4e98468947f231bb463bec922c
ToppCellfacs-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF12 GCG F8 PLEKHG1 HECW2

8.61e-0519510257f9b7f15006610ad591063d90e90367bd6083c7f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ISM1 F8 PLEKHG1 HECW2 DOCK6

8.82e-051961025023312af38f816a44b407e0daa32590d953caf99
ToppCellcontrol-immature_Neutrophil|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TET2 PER1 LPIN2 IGSF9B TNFAIP2

8.82e-051961025e34fd3e7a5b1c22a81fd3208e6d58bdb846d51c4
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

TET2 SH3BP2 DUSP6 PER1 TNFAIP2

9.25e-05198102561ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

F8 PLEKHG1 HECW2 MICAL3 DOCK6

9.25e-0519810259ab0db78394e730f6866b2db80047149024ad5f6
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

F8 PLEKHG1 HECW2 MICAL3 DOCK6

9.25e-051981025e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCellmild-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TET2 SH3BP2 DUSP6 PER1 TNFAIP2

9.69e-052001025934c2efc780318c66d667ca75be0de350361d351
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP6 FNDC1 MYOCD MICAL3 IGSF9B

9.69e-052001025a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellSevere-B_naive-13|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FAM131C TOE1 PDE8B C1QTNF12

1.47e-041161024f81a7c3e9cbf39124232d98e2a3a3e308137f391
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lhx6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GDF10 ARHGAP6 CHST7 VDR

1.67e-041201024a4e3f9a83bc52ccc75bcd64b1be4e2c5441f6d1a
ToppCellSevere-B_naive-13|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FAM131C TOE1 PDE8B C1QTNF12

1.67e-041201024d08edc09de8497714af55a6ca08a447cd71095e7
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRMPD1 ISM1 FNDC1 MYOCD

1.84e-04123102487401764a073c1808f214642a9c84299c78f7ec7
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DDX11 FAM229A RP1L1 IGSF9B

2.02e-04126102454247ce9ee0a4f123f1fb225600a4ec698510a86
DrugCephalosporanic acid, 7-amino [957-68-6]; Up 200; 14.6uM; MCF7; HT_HG-U133A

NCOA2 ACACB SH3BP2 ZNF696 GMIP BCR SOX13 MICAL3 TNFAIP2

2.28e-0719810093258_UP
DrugEnoxacin [74011-58-8]; Down 200; 12.4uM; HL60; HG-U133A

ATG4A ASXL1 SH3BP2 BCL7B NCOR1 LMF2 TRAPPC12 CHPF2

2.47e-0619610081597_DN
DrugNS-398; Down 200; 10uM; MCF7; HT_HG-U133A

NCOA2 SH3BP2 FRMPD1 USP19 LMF2 ZFYVE26 CHPF2 ELF4

2.57e-0619710086897_DN
DrugEburnamonine (-) [4880-88-0]; Down 200; 13.6uM; PC3; HT_HG-U133A

ARHGEF12 SOX13 F8 PPP1R26 BTBD7 CPEB1 VDR

2.10e-0519010077154_DN
DrugThiamphenicol [15318-45-3]; Down 200; 11.2uM; MCF7; HT_HG-U133A

HGSNAT ATP13A2 SOX13 F8 NCOR1 PKN1 TNFAIP2

2.32e-0519310077033_DN
Drug2-Chloropyrazine [14508-49-7]; Down 200; 35uM; MCF7; HT_HG-U133A

SH3BP2 ATP13A2 USP19 PDE8B BTBD7 ELF4 PKN1

2.40e-0519410073570_DN
Drugchlorpromazine hydrochloride; Down 200; 1uM; PC3; HT_HG-U133A

ACACB ARHGEF12 GMIP SOX13 NCOR1 CHPF2 CPEB1

2.40e-0519410071217_DN
DrugFinasteride [98319-26-7]; Down 200; 10.8uM; HL60; HT_HG-U133A

PER1 ZNF696 BTBD7 ZFYVE26 ELF4 TNFAIP2 VDR

2.40e-0519410072206_DN
DrugS(-)Eticlopride hydrochloride [97612-24-3]; Down 200; 10.6uM; MCF7; HT_HG-U133A

NCOA2 ACACB PER1 ARHGEF12 ELP1 PDE8B CHST7

2.48e-0519510073393_DN
DrugUrsolic acid [77-52-1]; Down 200; 8.8uM; PC3; HT_HG-U133A

ACACB SOX13 NCOR1 PDE8B BTBD7 ELF4 PKN1

2.48e-0519510075825_DN
DrugPrilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; MCF7; HT_HG-U133A

NCOA2 SH3BP2 ATP13A2 BTBD7 ZFYVE26 ELF4 VDR

2.56e-0519610072314_DN
DrugPrednisolone [50-24-8]; Down 200; 11uM; MCF7; HT_HG-U133A

ATG4A SH3BP2 BCL7B BCR LMF2 PKN1 TNFAIP2

2.56e-0519610077424_DN
DrugTubocurarine chloride pentahydrate (+) [6989-98-6]; Down 200; 5.2uM; MCF7; HT_HG-U133A

NCOA2 SH3BP2 BCAN NCOR1 LMF2 ELF4 TNFAIP2

2.65e-0519710072887_DN
DrugAcemetacin [53164-05-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A

SH3BP2 SOX13 ACOX3 NCOR1 LMF2 ZFYVE26 WIPF2

2.74e-0519810077442_DN
DrugAlthiazide [5588-16-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A

ACACB SH3BP2 PER1 ELP1 BCAN SOX13 VDR

2.74e-0519810076089_DN
DrugCarbachol [51-83-2]; Down 200; 21.8uM; PC3; HT_HG-U133A

SH3BP2 PER1 GMIP BCR SOX13 ARHGAP6 MICAL3

2.74e-0519810076742_DN
DrugTestosterone propionate [57-85-2]; Down 200; 11.6uM; HL60; HT_HG-U133A

SDHAF1 SH3BP2 DUSP6 LMF2 ZFYVE26 ELF4 WIPF2

2.83e-0519910071295_DN
DrugAC1NBZ8A

GAP43 TNFAIP2 VDR

6.39e-05181003CID004525693
DiseaseSystemic mastocytosis with associated clonal, hematologic non-mast-cell lineage disease

TET2 ASXL1

6.26e-054962C1301365
DiseaseMyelodysplastic syndrome

TET2 ASXL1

1.04e-045962cv:C3463824
DiseaseMYELODYSPLASTIC SYNDROME

TET2 ASXL1

1.04e-045962614286
Diseasechronic myelomonocytic leukemia (is_implicated_in)

TET2 ASXL1

1.04e-045962DOID:0080188 (is_implicated_in)
DiseaseMyeloid Leukemia, Chronic

ASXL1 PER1 BCR

1.15e-0429963C0023473
Diseasepolycystic ovary syndrome (implicated_via_orthology)

NCOA2 NCOR1

1.56e-046962DOID:11612 (implicated_via_orthology)
Diseaseoleoyl-oleoyl-glycerol (18:1/18:1) [1] measurement

BCL7B BUD13

1.56e-046962EFO_0800497
Diseasesmoking status measurement, chronic obstructive pulmonary disease

TET2 GLIS3 RASSF10 MICAL3

1.99e-0488964EFO_0000341, EFO_0006527
Disease1-oleoyl-2-arachidonoyl-GPE (18:1/20:4) measurement

BUD13 LIPC

2.18e-047962EFO_0800470
Disease1-oleoyl-2-linoleoyl-GPE (18:1/18:2) measurement

BUD13 LIPC

2.18e-047962EFO_0800443
Diseasesphingomyelin measurement

ISM1 BUD13 JMJD1C LIPC DOCK6 VDR

3.02e-04278966EFO_0010118
Disease1-palmitoyl-2-arachidonoyl-GPE (16:0/20:4) measurement

BUD13 LIPC

3.72e-049962EFO_0800409
Diseasesleep duration, triglyceride measurement

BUD13 JMJD1C LIPC MICAL3

3.77e-04104964EFO_0004530, EFO_0005271
Diseasecortical surface area measurement

NCOA2 TET2 GAP43 GLIS3 ARHGEF12 MARCHF7 PARD3B BCR GDF10 ATP13A2 PLEKHG1 NCOR1 RP1L1

4.14e-0413459613EFO_0010736
Diseaseprimary biliary cholangitis (is_implicated_in)

LBR VDR

4.63e-0410962DOID:12236 (is_implicated_in)
Disease1-stearoyl-2-linoleoyl-GPE (18:0/18:2) measurement

BUD13 LIPC

4.63e-0410962EFO_0800402
Disease1-stearoyl-2-oleoyl-GPE (18:0/18:1) measurement

BUD13 LIPC

5.65e-0411962EFO_0800269
Diseaseoleoyl-linoleoyl-glycerol (18:1/18:2) [1] measurement

BCL7B BUD13

5.65e-0411962EFO_0800332
Diseasesleep duration, high density lipoprotein cholesterol measurement

BUD13 JMJD1C LIPC DOCK6

6.68e-04121964EFO_0004612, EFO_0005271
DiseaseMalignant neoplasm of breast

NCOA2 FRMPD1 PER1 ELP1 CASP7 GDF10 NCOR1 LMF2 TRAPPC12 ZFYVE26 VDR

7.39e-0410749611C0006142
Diseasefree cholesterol to total lipids in very large HDL percentage

BUD13 LIPC DOCK6

7.74e-0455963EFO_0022288
Diseaselevel of Phosphatidylinositol (18:1_18:1) in blood serum

BUD13 DOCK6

7.98e-0413962OBA_2045159
Diseasecholesterol in medium HDL measurement

BUD13 LIPC DOCK6

9.51e-0459963EFO_0021903
Diseasefree cholesterol in IDL measurement

BUD13 JMJD1C LIPC

1.05e-0361963EFO_0022181
Diseasefree cholesterol in HDL measurement

BUD13 LIPC DOCK6

1.05e-0361963EFO_0022264
Diseasemyelodysplastic syndrome (implicated_via_orthology)

TET2 ASXL1

1.07e-0315962DOID:0050908 (implicated_via_orthology)
Diseasetotal lipids in HDL measurement

BUD13 LIPC DOCK6

1.15e-0363963EFO_0022307
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

ACACB JMJD1C LIPC LMAN2 DOCK6

1.21e-03243965EFO_0004612, EFO_0020944
DiseaseLipidemias

GCG LIPC

1.38e-0317962C1706412
DiseaseHyperlipidemia

GCG LIPC

1.38e-0317962C0020473
Diseasecortical thickness change measurement

GAP43 PARD3B

1.55e-0318962EFO_0021501
Diseaselevel of Phosphatidylinositol (18:0_18:1) in blood serum

BUD13 DOCK6

1.55e-0318962OBA_2045155
Diseaselevel of Phosphatidylcholine (15:0_18:2) in blood serum

BUD13 LIPC

1.55e-0318962OBA_2045065
Diseasemetabolite measurement, diet measurement

JMJD1C NCOR1 LIPC

1.63e-0371963EFO_0004725, EFO_0008111
Diseasechildhood trauma measurement, alcohol consumption measurement

PCDHGC5 MARCHF7 MYOCD

1.63e-0371963EFO_0007878, EFO_0007979
Diseasealkaline phosphatase measurement

NCOA2 TET2 ACACB BCL7B JMJD1C LIPC RP1L1 CHPF2 MICAL3 UBE2E3

1.73e-0310159610EFO_0004533
Diseaseapolipoprotein A 1 measurement

NCOA2 TET2 ACACB BUD13 JMJD1C LIPC LPIN2 DOCK6 CDH16

1.79e-03848969EFO_0004614
Diseasetriglyceride measurement, high density lipoprotein cholesterol measurement

ACACB BUD13 LIPC RP1L1 DOCK6

2.05e-03274965EFO_0004530, EFO_0004612
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

ACACB JMJD1C LIPC LMAN2 DOCK6

2.11e-03276965EFO_0004612, EFO_0020943
Diseaselevel of Phosphatidylinositol (18:0_18:2) in blood serum

BUD13 DOCK6

2.11e-0321962OBA_2045156
Diseasedocosahexaenoic acid to total fatty acids percentage

JMJD1C LIPC

2.11e-0321962EFO_0022262
Diseasevital capacity

TET2 TCF20 FRMPD1 GLIS3 PER1 ATP13A2 JMJD1C NCOR1 GAB3 ELF4 MICAL3

2.26e-0312369611EFO_0004312
Diseaseneuroticism measurement, cognitive function measurement

TET2 ASXL1 GLIS3 RASSF10 JMJD1C IGSF9B CPEB1

2.52e-03566967EFO_0007660, EFO_0008354
Diseasepancreatic carcinoma

RASSF10 PKN1 MICAL3 TNS4

2.55e-03174964EFO_0002618
Diseaseacute myeloid leukemia (is_implicated_in)

NCOA2 TET2 ASXL1

2.63e-0384963DOID:9119 (is_implicated_in)
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

ACACB BUD13 JMJD1C LIPC DOCK6

2.65e-03291965EFO_0008317, EFO_0020946
Diseasetestosterone measurement

TET2 NHSL2 GLIS3 JMJD1C PNMA6F ARHGAP6 TRAPPC12 PDE8B MYOCD LMAN2 VDR

2.88e-0312759611EFO_0004908

Protein segments in the cluster

PeptideGeneStartEntry
ASTSLPDPGDFDRNV

VDR

6

P11473
AARVDALDAASSPPN

ALKBH6

186

Q3KRA9
TNPSPSLAADLAGDA

LINC01547

66

P58512
RGLAAAPESQDSPEA

FAM229A

71

H3BQW9
GHQDSDSDLSPPRNR

BUD13

366

Q9BRD0
AGDRPPDSLTASNQS

ATG4A

196

Q8WYN0
ENDPLFARSPGADLS

ACOX3

56

O15254
AQAPDGASEPRASAS

BCR

81

P11274
PRQPSQADTGGDDSD

SH3BP2

431

P78314
GQRADPPNATASASS

C1QTNF12

36

Q5T7M4
AAREPNGFPSDASAN

BCL7B

66

Q9BQE9
QEAAQRASPAAPADG

CAMSAP3

186

Q9P1Y5
QAEPDNLARASASPD

ASXL1

491

Q8IXJ9
SGDASRPSSDNADSP

ARHGEF12

296

Q9NZN5
SEASLPNAGPRSAEA

RASSF10

131

A6NK89
DSADGRATPSENLVP

CPSF7

196

Q8N684
APRNDLSPASSGNAV

LBR

351

Q14739
SSDAAPSPELQANGT

ACACB

106

O00763
AAAAAESPPQEEGSA

HECW2

746

Q9P2P5
SNPASNPASDGLEAI

BCAN

366

Q96GW7
PSGNPADRQSPDAFE

PARD3B

91

Q8TEW8
PASESSASGAPLDEN

MICAL3

1056

Q7RTP6
SPKDNVDDPTGNFRS

LMAN2

301

Q12907
FPASEPDALNRAGDT

ELF4

136

Q99607
DLRARSQGSPEDSAP

GMIP

226

Q9P107
AQQPGRASASDSSAP

GPR158

46

Q5T848
LSQAAEPAGPQDSAT

FRMD8

371

Q9BZ67
AASSSLPRDDPNTNA

GAB3

151

Q8WWW8
EQDNSESPNGRTSPL

JMJD1C

2041

Q15652
GSEEQPSAAPSRLAA

GJD4

326

Q96KN9
AGDPEPRAAPNNSAD

GDF10

271

P55107
CPGPSLADDTDANSN

PER1

36

O15534
SEDPAAAQASPAQGD

PNMA6F

446

A0A0J9YX94
AASGARFPLDSAQDP

PCDHGC5

146

Q9Y5F6
QTDAADAIPPSRASG

PDE8B

46

O95263
EGSAPSNRLSPDDAN

LIPC

201

P11150
LQGNAPSDPDAVSAE

ELP1

861

O95163
RSFSASQADPLSDPD

GCG

31

P01275
SDDPSPGAIDSNNSL

F8

836

P00451
SRAAPTAASDQPDSA

PYM1

131

Q9BRP8
AAPADESQASTLRPA

DDX11

546

Q96FC9
LSEDDNPGASSAPAQ

HAUS8

366

Q9BT25
DSSGADQHPDSAPRQ

INSM2

371

Q96T92
GLSPDQTRSEDPQNS

MYOCD

161

Q8IZQ8
DGAARGSSLDADPQS

PRCD

31

Q00LT1
LSSANSLPAGEQDSP

ARHGAP6

926

O43182
PASPRLGQSQSQADE

C6orf132

371

Q5T0Z8
SLEPSPQSQAEDGRS

ATP13A2

116

Q9NQ11
ALDSADSQPAERTPS

CEFIP

456

Q711Q0
FDDNPDARLPNSGDL

DNAH6

2021

Q9C0G6
LGDPTQADSARPEQS

BRME1

161

Q0VDD7
PEDSNDSRRGSGSPE

DOCK6

166

Q96HP0
RIAFDAESDPSNAPG

ELMO2

321

Q96JJ3
SSGDPNPDRACLASN

FRMPD1

1016

Q5SYB0
DGEDAPATNSNAPSR

FNDC1

746

Q4ZHG4
SLQPATSPRDAAAEG

GLIS3

526

Q8NEA6
DSLPSGPSQDDSLQA

FAM131C

196

Q96AQ9
GADPDSRDFDNNTPL

FEM1A

571

Q9BSK4
RSDFPLAAPENASTG

BTBD7

1036

Q9P203
QADSGPINDTDANPR

CASP7

196

P55210
PSASEVPDNRASEAS

MARCHF7

331

Q9H992
SSGRDAQAAPPRDLD

HGSNAT

56

Q68CP4
SAQESSRGLPDANDL

CPEB1

81

Q9BZB8
RDPNSATDSDGSPLS

DUSP6

186

Q16828
DSTSDDSNFLNPPRG

ISM1

181

B1AKI9
TRLSAEDADAPGSPN

CDH16

356

O75309
PSRDPLNNSGGFESA

SESN2

241

P58004
EEGEALSSPQPASRA

RNF157

546

Q96PX1
NSDSPAQRAEAPDGQ

PPP1R12C

601

Q9BZL4
DSGAASEQATAAPNP

LMF2

681

Q9BU23
STPQADSEREASPLG

NHSL2

1061

Q5HYW2
GDAATEQAAPQAPAS

GAP43

116

P17677
DSPENATSRGNTEPA

NCOR1

736

O75376
SASASEGNPFPRESQ

PPP1R26

801

Q5T8A7
QPDDGDSPRNPHDST

SDHAF1

91

A6NFY7
QAAPDDTQGSPDLGA

PKN1

196

Q16512
DPAARAPDTANLTTA

CHST7

176

Q9NS84
GPQNPDSRARLDQSD

CHPF2

51

Q9P2E5
NLPPAVSSERADGQS

NCOA2

616

Q15596
PQPGDPARASQDSAD

SOX13

46

Q9UN79
RDAQDPSQSLGAPEA

USP42

881

Q9H9J4
PDLGPAAEAAASQAS

USP19

1231

O94966
QPSSAEPEDAAGSRQ

TNFAIP2

56

Q03169
GNDVPDLNLSSGDPD

UBN2

366

Q6ZU65
DPSASERQSGSQLEP

RP1L1

1461

Q8IWN7
EDAAPSSGGAPRQDA

TRAPPC12

121

Q8WVT3
RAPSESSDDQGQPAA

IGSF9B

791

Q9UPX0
EVPASAQSRPGEDSN

TNS4

491

Q8IZW8
SSGSSDADQRDPAAP

UBE2E3

16

Q969T4
QAAQSTEPAAEAGAP

ZNF696

41

Q9H7X3
LNASPAAREEATSPG

TCF20

571

Q9UGU0
KASPSSPGRQDSDED

TJP3

101

O95049
LPDSNDSPASASRVA

ZNF415

76

Q09FC8
PFSSSELQRDNPATG

PLEKHG1

61

Q9ULL1
GSARASEQPENAESP

TXLNB

81

Q8N3L3
PVSAASGRPQDDTDS

WIPF2

126

Q8TF74
RNPGESSQPNVSDLS

TET2

131

Q6N021
RPADSDDTNAAGPSA

TTLL10

121

Q6ZVT0
TEPANDSLSSPGAAN

ZFYVE26

536

Q68DK2
DRATSEVPGSQASPN

TOE1

416

Q96GM8
SELAGLDASQPSRNP

TMEM14EP

46

Q6UXP3
APGTTAVSSNRNPED

nan

66

Q8N7P7
SKEPAGARPAENDSS

LPIN2

591

Q92539
ARVADADPASAPSQG

RAB34

126

P0DI83