Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionSH3 domain binding

EFS NCF1 CABYR ABI1 SH3BP2 CBL ARHGAP27 NCF1C NCF1B TP53BP2

1.91e-0614320110GO:0017124
GeneOntologyMolecularFunctionprotein domain specific binding

DLGAP2 PAG1 EFS NCF1 BLNK MCL1 SIT1 CABYR BAIAP2 GNAS CACNA1C ABI1 SH3BP2 TACC2 CBL SHROOM2 TAMALIN CASK ARHGAP5 ARHGAP27 NCF1C NCF1B TOP1 SMAD2 TP53BP2

2.64e-0687520125GO:0019904
GeneOntologyMolecularFunctionbeta-catenin binding

SHROOM2 CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

3.54e-061202019GO:0008013
GeneOntologyMolecularFunctioncalcium ion binding

PRRG1 TENM2 CAPN8 CABYR UMODL1 PCDH15 PRRG3 DOC2B PCDHGA10 CBL RPH3A CDH24 THBS3 CDH22 SNCB CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

2.33e-0574920121GO:0005509
GeneOntologyMolecularFunctioncadherin binding

PTPRH BAIAP2 ABI1 ANK3 CBL CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

4.18e-0533920113GO:0045296
GeneOntologyMolecularFunctionsuperoxide-generating NADPH oxidase activator activity

NCF1 NCF1C NCF1B

1.14e-04102013GO:0016176
GeneOntologyMolecularFunctioncell adhesion molecule binding

TENM2 PTPRH GPNMB BAIAP2 COL5A1 ABI1 ANK3 GRIN2A CBL CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

1.24e-0459920117GO:0050839
GeneOntologyMolecularFunctionsuperoxide-generating NAD(P)H oxidase activity

NCF1 NCF1C NCF1B

2.07e-04122013GO:0016175
GeneOntologyMolecularFunctionco-SMAD binding

USP9Y SMAD2 SMAD6

2.07e-04122013GO:0070410
GeneOntologyMolecularFunctionSMAD binding

USP9Y LDLRAD4 YY1 PRDM16 SMAD2 SMAD6

2.33e-04862016GO:0046332
GeneOntologyBiologicalProcesscell-cell adhesion mediated by cadherin

FER CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

1.08e-09501999GO:0044331
GeneOntologyBiologicalProcessadherens junction organization

FER CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

6.80e-09611999GO:0034332
GeneOntologyBiologicalProcesscalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

3.98e-08531998GO:0016339
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

PTPRG PCDH15 PCDHGA10 CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

2.12e-0618719911GO:0007156
GeneOntologyBiologicalProcesscell-cell junction assembly

ACE FER CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

5.30e-0616719910GO:0007043
GeneOntologyBiologicalProcessneutrophil-mediated killing of gram-positive bacterium

NCF1 NCF1C NCF1B

8.72e-0651993GO:0070946
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

TENM2 PTPRG PCDH15 PCDHGA10 SCARF1 CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

1.17e-0531319913GO:0098742
GeneOntologyBiologicalProcesscell morphogenesis

TANC2 MYO10 ADARB1 TENM2 PCDH15 UNC93B1 BAIAP2 STRC STRCP1 ABI1 ANK3 PLEKHG4 SHROOM2 CERT1 CASK CDH24 CDH22 ARHGEF40 ZNF335 LRP6 CDH2 CDH7 CDH8 CDH11 DCLK1 CDH12 CDH13 EPHA10

1.20e-05119419928GO:0000902
GeneOntologyBiologicalProcessresponse to yeast

NCF1 NPY NCF1C NCF1B

2.31e-05181994GO:0001878
GeneOntologyBiologicalProcesscell-cell junction organization

ACE FER SHROOM2 CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

2.84e-0524619911GO:0045216
GeneOntologyBiologicalProcessNADP catabolic process

NCF1 NCF1C NCF1B

3.01e-0571993GO:0006742
GeneOntologyBiologicalProcessneutrophil-mediated killing of fungus

NCF1 NCF1C NCF1B

3.01e-0571993GO:0070947
GeneOntologyBiologicalProcesssynaptic signaling

DLGAP2 JPH4 ACE ADARB1 TENM2 SLC24A2 BAIAP2 NPY DOC2B CACNA1C ABI1 APBA2 GRIN2A RPH3A CASK SLC6A9 SNCAIP LRP6 PRKCB SNCB CDH2 CDH8 CDH11

7.18e-0597619923GO:0099536
GeneOntologyBiologicalProcessregulation of Wnt signaling pathway involved in heart development

LRP6 ALPK2

9.26e-0521992GO:0003307
GeneOntologyBiologicalProcessnegative regulation of Wnt signaling pathway involved in heart development

LRP6 ALPK2

9.26e-0521992GO:0003308
GeneOntologyBiologicalProcesstrans-synaptic signaling

DLGAP2 JPH4 ACE ADARB1 TENM2 SLC24A2 BAIAP2 NPY DOC2B CACNA1C APBA2 GRIN2A RPH3A CASK SLC6A9 SNCAIP LRP6 PRKCB SNCB CDH2 CDH8 CDH11

1.13e-0493919922GO:0099537
GeneOntologyBiologicalProcessregulation of respiratory burst involved in inflammatory response

NCF1 NCF1C NCF1B

1.38e-04111993GO:0060264
GeneOntologyBiologicalProcessrespiratory burst involved in inflammatory response

NCF1 NCF1C NCF1B

2.36e-04131993GO:0002536
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

DLGAP2 JPH4 ACE ADARB1 SLC24A2 BAIAP2 NPY DOC2B CACNA1C APBA2 GRIN2A RPH3A CASK SLC6A9 SNCAIP LRP6 PRKCB SNCB CDH2 CDH8 CDH11

2.72e-0493119921GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

DLGAP2 JPH4 ACE ADARB1 SLC24A2 BAIAP2 NPY DOC2B CACNA1C APBA2 GRIN2A RPH3A CASK SLC6A9 SNCAIP LRP6 PRKCB SNCB CDH2 CDH8 CDH11

2.72e-0493119921GO:0007268
GeneOntologyBiologicalProcesszygotic specification of dorsal/ventral axis

SMAD2 SMAD6

2.76e-0431992GO:0007352
GeneOntologyBiologicalProcesscell-cell adhesion

PAG1 MYO10 TENM2 PTPRG FER PCDH15 GPNMB BAIAP2 GNAS VMP1 MIA3 ANK3 PCDHGA10 SCARF1 CDH24 CDH22 LRP6 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

3.03e-04107719923GO:0098609
GeneOntologyCellularComponentcatenin complex

CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

5.27e-10322008GO:0016342
GeneOntologyCellularComponentextrinsic component of membrane

TENM2 GNAS DOC2B PLEKHG4 RPH3A CDH24 CDH22 ARHGEF40 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

4.97e-0823020014GO:0019898
GeneOntologyCellularComponentextrinsic component of plasma membrane

TENM2 GNAS CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

8.20e-0713720010GO:0019897
GeneOntologyCellularComponentadherens junction

FER BAIAP2 SHROOM2 CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

6.56e-0621220011GO:0005912
GeneOntologyCellularComponentactin-based cell projection

MYO10 TENM2 TBC1D10C CLCA1 PTPRH PCDH15 BAIAP2 STRC STRCP1 ABI1

3.61e-0427820010GO:0098858
GeneOntologyCellularComponentcell-cell junction

TENM2 FER BAIAP2 AMOTL2 ANK3 SHROOM2 CASK CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

5.91e-0459120015GO:0005911
GeneOntologyCellularComponentNADPH oxidase complex

NCF1 NCF1C NCF1B

6.33e-04182003GO:0043020
GeneOntologyCellularComponentsomatodendritic compartment

TANC2 DLGAP2 JPH4 MYO10 NCF1 SREBF2 TENM2 BAIAP2 GNAS NPY CACNA1C ANK3 APBA2 GRIN2A SHROOM2 RPH3A CASK SNCAIP LRP6 SNCB NCF1C NCF1B TOP1 EPHA10

7.06e-04122820024GO:0036477
GeneOntologyCellularComponentcollagen type XI trimer

COL5A1 COL11A2

8.94e-0452002GO:0005592
MousePhenoabnormal angiotensin I-converting enzyme activity

NCF1 ACE NCF1C NCF1B

2.76e-0761654MP:0013254
MousePhenoincreased angiotensin I-converting enzyme activity

NCF1 ACE NCF1C NCF1B

2.76e-0761654MP:0003184
MousePhenoimpaired smooth muscle contractility

NCF1 APEX1 CAVIN1 NCF1C NCF1B

5.26e-05351655MP:0000740
MousePhenoliver abscess

NCF1 NCF1C NCF1B

5.46e-0571653MP:0003332
MousePhenodecreased vasoconstriction

NCF1 APEX1 NCF1C NCF1B

1.16e-04221654MP:0003026
MousePhenoabnormal cued conditioning behavior

NCF1 PTPRG TULP4 CACNA1C PRKCB TMEM35A CDH2 NCF1C NCF1B

1.23e-041611659MP:0001454
MousePhenoincreased PP cell number

INSM1 PDX1

1.38e-0421652MP:0009185
MousePhenoabnormal pancreatic endocrine progenitor cell physiology

INSM1 PDX1

1.38e-0421652MP:0011911
MousePhenoincreased circulating renin level

NCF1 ACE NCF1C NCF1B

1.39e-04231654MP:0003352
DomainCadherin_C

CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12

5.53e-09251987PF01049
DomainCadherin_cytoplasmic-dom

CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12

5.53e-09251987IPR000233
DomainCatenin_binding_dom

CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12

1.73e-08291987IPR027397
Domain-

CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12

1.73e-082919874.10.900.10
DomainCadherin_CS

PCDH15 PCDHGA10 CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

2.45e-0710919810IPR020894
DomainCADHERIN_1

PCDH15 PCDHGA10 CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

3.44e-0711319810PS00232
DomainCadherin

PCDH15 PCDHGA10 CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

3.44e-0711319810PF00028
DomainCADHERIN_2

PCDH15 PCDHGA10 CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

3.74e-0711419810PS50268
Domain-

PCDH15 PCDHGA10 CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

3.74e-07114198102.60.40.60
DomainCA

PCDH15 PCDHGA10 CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

4.05e-0711519810SM00112
DomainCadherin-like

PCDH15 PCDHGA10 CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

4.40e-0711619810IPR015919
DomainCadherin

PCDH15 PCDHGA10 CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

5.16e-0711819810IPR002126
DomainSH3

FNBP1 EFS NCF1 BAIAP2 SKAP2 MIA3 ABI1 ARHGAP10 CASK ARHGAP27 FYB1 TP53BP2

3.45e-0621619812SM00326
DomainSH3

FNBP1 EFS NCF1 BAIAP2 SKAP2 MIA3 ABI1 ARHGAP10 CASK ARHGAP27 FYB1 TP53BP2

3.45e-0621619812PS50002
DomainSH3_domain

FNBP1 EFS NCF1 BAIAP2 SKAP2 MIA3 ABI1 ARHGAP10 CASK ARHGAP27 FYB1 TP53BP2

4.17e-0622019812IPR001452
DomainSMAD_FHA_domain

IRF7 PHF12 APLF SMAD2 SMAD6

2.21e-04521985IPR008984
Domain-

MYO10 SSRP1 ARHGAP25 SKAP2 ARHGAP23 PLEKHG4 ARHGAP10 SH3BP2 APBA2 CERT1 ARHGEF40 MTMR4 ARHGAP27

2.86e-04391198132.30.29.30
DomainRhoGAP

ARHGAP25 ARHGAP23 ARHGAP10 ARHGAP5 ARHGAP27

5.05e-04621985SM00324
DomainRhoGAP

ARHGAP25 ARHGAP23 ARHGAP10 ARHGAP5 ARHGAP27

5.44e-04631985PF00620
DomainRhoGAP_dom

ARHGAP25 ARHGAP23 ARHGAP10 ARHGAP5 ARHGAP27

5.85e-04641985IPR000198
DomainRHOGAP

ARHGAP25 ARHGAP23 ARHGAP10 ARHGAP5 ARHGAP27

5.85e-04641985PS50238
Domain-

ARHGAP25 ARHGAP23 ARHGAP10 ARHGAP5 ARHGAP27

5.85e-046419851.10.555.10
DomainSMAD_dom-like

IRF7 SMAD2 SMAD6

5.94e-04161983IPR017855
Domain-

IRF7 SMAD2 SMAD6

5.94e-041619832.60.200.10
DomainPH_dom-like

MYO10 SSRP1 ARHGAP25 SKAP2 ARHGAP23 PLEKHG4 ARHGAP10 SH3BP2 APBA2 CERT1 ARHGEF40 MTMR4 ARHGAP27

6.43e-0442619813IPR011993
DomainPH

MYO10 ARHGAP25 SKAP2 ARHGAP23 PLEKHG4 ARHGAP10 SH3BP2 CERT1 ARHGEF40 ARHGAP27

7.92e-0427819810SM00233
DomainPH_DOMAIN

MYO10 ARHGAP25 SKAP2 ARHGAP23 PLEKHG4 ARHGAP10 SH3BP2 CERT1 ARHGEF40 ARHGAP27

8.15e-0427919810PS50003
DomainPH_domain

MYO10 ARHGAP25 SKAP2 ARHGAP23 PLEKHG4 ARHGAP10 SH3BP2 CERT1 ARHGEF40 ARHGAP27

8.37e-0428019810IPR001849
PathwayWP_HIPPO_SIGNALING_REGULATION

GNAS CDH24 CDH22 PRKCB CDH2 CDH7 CDH8 CDH11 CDH12 CDH13 SMAD2

6.94e-099815011M39830
PathwayREACTOME_ADHERENS_JUNCTIONS_INTERACTIONS

TNRC6B CDH24 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

1.67e-07581508M11980
PathwayREACTOME_ADHERENS_JUNCTIONS_INTERACTIONS

CDH24 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

1.86e-07401507MM15060
PathwayREACTOME_CELL_CELL_JUNCTION_ORGANIZATION

CDH24 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

6.86e-07481507MM15069
PathwayREACTOME_CELL_CELL_COMMUNICATION

TNRC6B SKAP2 CASK CDH24 FYB1 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

7.98e-0715515011M522
PathwayREACTOME_CELL_CELL_COMMUNICATION

SKAP2 CDH24 FYB1 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

8.11e-07961509MM14592
PathwayREACTOME_CELL_CELL_JUNCTION_ORGANIZATION

TNRC6B CDH24 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

5.06e-06901508M820
PathwayREACTOME_CELL_JUNCTION_ORGANIZATION

CDH24 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

1.22e-05731507MM15126
PathwayREACTOME_RAC1_GTPASE_CYCLE

NCF1 ARHGAP25 BAIAP2 ABI1 ARHGAP23 ARHGAP10 ARHGAP5 ARHGAP27 NCF1C NCF1B

1.76e-0517515010MM15599
PathwayREACTOME_CELL_JUNCTION_ORGANIZATION

TNRC6B CDH24 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

3.49e-051171508M19248
PathwayREACTOME_CDH11_HOMOTYPIC_AND_HETEROTYPIC_INTERACTIONS

CDH24 CDH8 CDH11

4.01e-0571503M48038
PathwayWP_HIPPOMERLIN_SIGNALING_DYSREGULATION

CDH24 CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

4.45e-051211508M39823
PathwayREACTOME_CROSS_PRESENTATION_OF_PARTICULATE_EXOGENOUS_ANTIGENS_PHAGOSOMES

NCF1 NCF1C NCF1B

9.46e-0591503MM14524
PathwayREACTOME_RHO_GTPASES_ACTIVATE_NADPH_OXIDASES

NCF1 PRKCB NCF1C NCF1B

1.31e-04251504MM15269
PathwayREACTOME_RAC1_GTPASE_CYCLE

NCF1 ARHGAP25 BAIAP2 ABI1 ARHGAP23 PLEKHG4 ARHGAP10 ARHGAP5 ARHGAP27

1.55e-041841509M41809
PathwayREACTOME_REGULATION_OF_CDH11_FUNCTION

CDH24 CDH8 CDH11

1.83e-04111503M48015
PathwayREACTOME_RHO_GTPASE_CYCLE

FNBP1 NCF1 ARHGAP25 BAIAP2 ABI1 ARHGAP23 ARHGAP10 ARHGAP5 CAVIN1 ARHGAP27 MTX1 NCF1C NCF1B TOR1AIP1

2.48e-0443915014MM15595
PathwayREACTOME_RHO_GTPASE_CYCLE

FNBP1 NCF1 ARHGAP25 BAIAP2 ABI1 ARHGAP23 PLEKHG4 ARHGAP10 ARHGAP5 ARHGEF40 CAVIN1 ARHGAP27 MTX1 TOR1AIP1

3.19e-0445015014M27078
PathwayREACTOME_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION

TNRC6B CDH24 CDH8 CDH11

3.51e-04321504M48012
PathwayREACTOME_RAC3_GTPASE_CYCLE

NCF1 BAIAP2 ABI1 ARHGAP5 NCF1C NCF1B

4.68e-04931506MM15609
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

PAG1 NCF1 COL6A5 FER BAIAP2 COL5A1 ABI1 COL11A2 CBL THBS3 PRKCB NCF1C NCF1B

5.25e-0441815013MM15587
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

FNBP1 CENPF NCF1 ARHGAP25 BAIAP2 ABI1 ARHGAP23 ARHGAP10 ARHGAP5 DYNC1LI1 PRKCB CAVIN1 ARHGAP27 MTX1 NCF1C NCF1B TOR1AIP1

5.42e-0464915017MM15690
PathwayPID_TCR_PATHWAY

PAG1 SH3BP2 CBL PRKCB FYB1

5.87e-04641505M34
Pubmed

Differential Spatiotemporal Expression of Type I and Type II Cadherins Associated With the Segmentation of the Central Nervous System and Formation of Brain Nuclei in the Developing Mouse.

CDH24 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

1.33e-1215204733833667
Pubmed

Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy.

CDH24 CDH22 CDH7 CDH8 CDH11 CDH12

3.39e-1112204622102170
Pubmed

Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity.

CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

6.27e-111320469615235
Pubmed

Motor neuron position and topographic order imposed by β- and γ-catenin activities.

CDH22 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13

3.01e-1029204722036570
Pubmed

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.

CDH24 CDH2 CDH7 CDH11 CDH12 CDH13

1.37e-092020467806582
Pubmed

Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue.

CDH2 CDH8 CDH11 CDH12 CDH13

1.63e-091020452059658
Pubmed

A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.

TENM2 CDH24 CDH2 CDH7 CDH8 CDH11 CDH12 CDH13 EPHA10

3.56e-0991204928558017
Pubmed

Type II cadherins guide assembly of a direction-selective retinal circuit.

CDH24 CDH22 CDH7 CDH8 CDH11 CDH12

4.66e-0924204625126785
Pubmed

Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin.

CDH8 CDH11 CDH12 CDH13

5.72e-09520447982033
Pubmed

Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: a possible role for angiotensin-converting enzyme and the receptors for angiotensin II and aldosterone.

NCF1 ACE NCF1C NCF1B

1.71e-086204415123520
Pubmed

Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps.

NCF1 MCL1 NCF1C NCF1B

1.71e-086204428515366
Pubmed

Killing activity of neutrophils is mediated through activation of proteases by K+ flux.

NCF1 LTF NCF1C NCF1B

3.97e-087204411907569
Pubmed

ATF4 Regulates CD4+ T Cell Immune Responses through Metabolic Reprogramming.

NCF1 EIF2AK1 NCF1C NCF1B

3.97e-087204429742431
Pubmed

Developmental expression of NADPH phagocytic oxidase components in mouse embryos.

NCF1 LTF NCF1C NCF1B

1.42e-079204410447107
Pubmed

NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.

NCF1 NCF1C NCF1B

1.99e-073204318787174
Pubmed

Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice.

NCF1 NCF1C NCF1B

1.99e-073204324873968
Pubmed

Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.

NCF1 NCF1C NCF1B

1.99e-073204320142487
Pubmed

p47(phox) contributes to albuminuria and kidney fibrosis in mice.

NCF1 NCF1C NCF1B

1.99e-073204325565313
Pubmed

Knockout of neutrophil cytosolic factor 1 ameliorates neuroinflammation and motor deficit after traumatic brain injury.

NCF1 NCF1C NCF1B

1.99e-073204339357591
Pubmed

Genetic demonstration of p47phox-dependent superoxide anion production in murine vascular smooth muscle cells.

NCF1 NCF1C NCF1B

1.99e-073204311435342
Pubmed

Virulence comparisons of Aspergillus nidulans mutants are confounded by the inflammatory response of p47phox-/- mice.

NCF1 NCF1C NCF1B

1.99e-073204316041040
Pubmed

Mycobacteria-induced Gr-1+ subsets from distinct myeloid lineages have opposite effects on T cell expansion.

NCF1 NCF1C NCF1B

1.99e-073204317307863
Pubmed

Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss.

NCF1 NCF1C NCF1B

1.99e-073204327829407
Pubmed

The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis.

NCF1 NCF1C NCF1B

1.99e-073204322376231
Pubmed

Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.

NCF1 NCF1C NCF1B

1.99e-073204312364355
Pubmed

P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+.

NCF1 NCF1C NCF1B

1.99e-073204310670582
Pubmed

Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.

NCF1 NCF1C NCF1B

1.99e-073204326528554
Pubmed

The role of reactive oxygen species in immunopathogenesis of rheumatoid arthritis.

NCF1 NCF1C NCF1B

1.99e-073204319052348
Pubmed

Effect of early particulate air pollution exposure on obesity in mice: role of p47phox.

NCF1 NCF1C NCF1B

1.99e-073204320864666
Pubmed

Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice.

NCF1 NCF1C NCF1B

1.99e-073204317114280
Pubmed

Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction.

NCF1 NCF1C NCF1B

1.99e-073204317332431
Pubmed

Lpp of Escherichia coli K1 inhibits host ROS production to counteract neutrophil-mediated elimination.

NCF1 NCF1C NCF1B

1.99e-073204336592568
Pubmed

Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression.

NCF1 NCF1C NCF1B

1.99e-073204330504842
Pubmed

Direct interaction of HIV gp120 with neuronal CXCR4 and CCR5 receptors induces cofilin-actin rod pathology via a cellular prion protein- and NOX-dependent mechanism.

NCF1 NCF1C NCF1B

1.99e-073204333705493
Pubmed

Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: studies on NADPH oxidase knockout mice.

NCF1 NCF1C NCF1B

1.99e-073204315513930
Pubmed

Phosphoinositide 3-kinase regulates the phosphorylation of NADPH oxidase component p47(phox) by controlling cPKC/PKCdelta but not Akt.

NCF1 NCF1C NCF1B

1.99e-073204315033459
Pubmed

p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation.

NCF1 NCF1C NCF1B

1.99e-073204320817944
Pubmed

Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation.

NCF1 NCF1C NCF1B

1.99e-073204323024271
Pubmed

Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene.

NCF1 NCF1C NCF1B

1.99e-073204315310853
Pubmed

Ncf1 Governs Immune Niches in the Lung to Mediate Pulmonary Inflammation in Mice.

NCF1 NCF1C NCF1B

1.99e-073204334970267
Pubmed

Germ-free mice deficient of reactive oxygen species have increased arthritis susceptibility.

NCF1 NCF1C NCF1B

1.99e-073204325689796
Pubmed

Opposing roles of p47phox in basal versus angiotensin II-stimulated alterations in vascular O2- production, vascular tone, and mitogen-activated protein kinase activation.

NCF1 NCF1C NCF1B

1.99e-073204314993144
Pubmed

The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression.

NCF1 NCF1C NCF1B

1.99e-073204312031896
Pubmed

Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice.

NCF1 NCF1C NCF1B

1.99e-073204315936744
Pubmed

NADPH oxidase p47phox siRNA attenuates adventitial fibroblasts proliferation and migration in apoE(-/-) mouse.

NCF1 NCF1C NCF1B

1.99e-073204325628043
Pubmed

Mechanism of endothelial cell NADPH oxidase activation by angiotensin II. Role of the p47phox subunit.

NCF1 NCF1C NCF1B

1.99e-073204312560337
Pubmed

Inhibition of endothelial Nox2 activation by LMH001 protects mice from angiotensin II-induced vascular oxidative stress, hypertension and aortic aneurysm.

NCF1 NCF1C NCF1B

1.99e-073204335276443
Pubmed

Reactive oxygen species modulate growth of cerebral aneurysms: a study using the free radical scavenger edaravone and p47phox(-/-) mice.

NCF1 NCF1C NCF1B

1.99e-073204319381132
Pubmed

Superoxide prevents nitric oxide-mediated suppression of helper T lymphocytes: decreased autoimmune encephalomyelitis in nicotinamide adenine dinucleotide phosphate oxidase knockout mice.

NCF1 NCF1C NCF1B

1.99e-073204310799876
Pubmed

Essential role of the NADPH oxidase subunit p47(phox) in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-alpha.

NCF1 NCF1C NCF1B

1.99e-073204311834706
Pubmed

Virulence and cellular interactions of Burkholderia multivorans in chronic granulomatous disease.

NCF1 NCF1C NCF1B

1.99e-073204319635825
Pubmed

The NCF1 variant p.R90H aggravates autoimmunity by facilitating the activation of plasmacytoid dendritic cells.

NCF1 NCF1C NCF1B

1.99e-073204335788118
Pubmed

Hydrophobic bile salts induce hepatocyte shrinkage via NADPH oxidase activation.

NCF1 NCF1C NCF1B

1.99e-073204317310103
Pubmed

Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.

NCF1 NCF1C NCF1B

1.99e-073204324358335
Pubmed

Molecular characterization of the mouse p47-phox (Ncf1) gene and comparative analysis of the mouse p47-phox (Ncf1) gene to the human NCF1 gene.

NCF1 NCF1C NCF1B

1.99e-073204310891396
Pubmed

NAD(P)H oxidase subunit p47phox is elevated, and p47phox knockout prevents diaphragm contractile dysfunction in heart failure.

NCF1 NCF1C NCF1B

1.99e-073204326209274
Pubmed

NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.

NCF1 NCF1C NCF1B

1.99e-073204311018074
Pubmed

Enhanced host defense after gene transfer in the murine p47phox-deficient model of chronic granulomatous disease.

NCF1 NCF1C NCF1B

1.99e-07320439116268
Pubmed

Mice producing less reactive oxygen species are relatively resistant to collagen glycopeptide vaccination against arthritis.

NCF1 NCF1C NCF1B

1.99e-073204320686129
Pubmed

Angiotensin II induced catabolic effect and muscle atrophy are redox dependent.

NCF1 NCF1C NCF1B

1.99e-073204321570954
Pubmed

Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity.

NCF1 NCF1C NCF1B

1.99e-073204323482812
Pubmed

The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs.

NCF1 NCF1C NCF1B

1.99e-073204310085000
Pubmed

Methamphetamine alters occludin expression via NADPH oxidase-induced oxidative insult and intact caveolae.

NCF1 NCF1C NCF1B

1.99e-073204321435178
Pubmed

Mycobacterial infection induces higher interleukin-1β and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase.

NCF1 NCF1C NCF1B

1.99e-073204329228045
Pubmed

Generation of reactive oxygen species (ROS) is a key factor for stimulation of macrophage proliferation by ceramide 1-phosphate.

NCF1 NCF1C NCF1B

1.99e-073204322155727
Pubmed

Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction.

NCF1 NCF1C NCF1B

1.99e-073204324576409
Pubmed

The p47phox deficiency significantly attenuates the pathogenicity of Chlamydia muridarum in the mouse oviduct but not uterine tissues.

NCF1 NCF1C NCF1B

1.99e-073204326645958
Pubmed

NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.

NCF1 NCF1C NCF1B

1.99e-073204324549323
Pubmed

Participation of mitochondrial respiratory complex III in neutrophil activation and lung injury.

NCF1 NCF1C NCF1B

1.99e-073204319168575
Pubmed

A Feed-Forward Mechanism Involving the NOX Complex and RyR-Mediated Ca2+ Release During Axonal Specification.

NCF1 NCF1C NCF1B

1.99e-073204327798190
Pubmed

Conditional haploinsufficiency of NCF1 (encoding p47(phox)), a signaling gene with a heterozygous phenotype potentially subject to natural selection.

NCF1 NCF1C NCF1B

1.99e-073204315626477
Pubmed

Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.

NCF1 NCF1C NCF1B

1.99e-073204322319452
Pubmed

Endosomal acidification and activation of NADPH oxidase isoforms are upstream events in hyperosmolarity-induced hepatocyte apoptosis.

NCF1 NCF1C NCF1B

1.99e-073204316772302
Pubmed

Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice.

NCF1 NCF1C NCF1B

1.99e-073204332504071
Pubmed

Effect of p47phox gene deletion on ROS production and oxygen sensing in mouse carotid body chemoreceptor cells.

NCF1 NCF1C NCF1B

1.99e-073204316280459
Pubmed

NADPH oxidase modulates myocardial Akt, ERK1/2 activation, and angiogenesis after hypoxia-reoxygenation.

NCF1 NCF1C NCF1B

1.99e-073204317220182
Pubmed

The p47phox mouse knock-out model of chronic granulomatous disease.

NCF1 NCF1C NCF1B

1.99e-07320437650482
Pubmed

Disseminated trichosporonosis in a murine model of chronic granulomatous disease.

NCF1 NCF1C NCF1B

1.99e-073204312868577
Pubmed

NADPH oxidase mediates striatal neuronal injury after transient global cerebral ischemia.

NCF1 NCF1C NCF1B

1.99e-073204320859296
Pubmed

Loss of NADPH oxidase-derived superoxide skews macrophage phenotypes to delay type 1 diabetes.

NCF1 NCF1C NCF1B

1.99e-073204325288672
Pubmed

Lack of reactive oxygen species breaks T cell tolerance to collagen type II and allows development of arthritis in mice.

NCF1 NCF1C NCF1B

1.99e-073204317641008
Pubmed

Hyperoxia impairs postnatal alveolar epithelial development via NADPH oxidase in newborn mice.

NCF1 NCF1C NCF1B

1.99e-073204319411313
Pubmed

Critical role for p47phox in renin-angiotensin system activation and blood pressure regulation.

NCF1 NCF1C NCF1B

1.99e-073204316843452
Pubmed

A glucose-6-phosphate isomerase peptide induces T and B cell-dependent chronic arthritis in C57BL/10 mice: arthritis without reactive oxygen species and complement.

NCF1 NCF1C NCF1B

1.99e-073204323911657
Pubmed

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.

NCF1 NCF1C NCF1B

1.99e-073204327044504
Pubmed

p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.

NCF1 NCF1C NCF1B

1.99e-073204322184329
Pubmed

Natural Loss-of-Function Mutations in Qa2 and NCF1 Cause the Spread of Mannan-Induced Psoriasis.

NCF1 NCF1C NCF1B

1.99e-073204333545139
Pubmed

Neutrophil Cytosolic Factor 1 in Dendritic Cells Promotes Autoreactive CD8+ T Cell Activation via Cross-Presentation in Type 1 Diabetes.

NCF1 NCF1C NCF1B

1.99e-073204331118934
Pubmed

Intermittent hypoxia has organ-specific effects on oxidative stress.

NCF1 NCF1C NCF1B

1.99e-073204318703411
Pubmed

Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms.

NCF1 NCF1C NCF1B

1.99e-073204323918780
Pubmed

NADPH oxidase NOX2 mediates TLR2/6-dependent release of GM-CSF from endothelial cells.

NCF1 NCF1C NCF1B

1.99e-073204328274989
Pubmed

NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities.

NCF1 NCF1C NCF1B

1.99e-073204334557202
Pubmed

Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms.

NCF1 NCF1C NCF1B

1.99e-073204328467721
Pubmed

Reactive oxygen species delay control of lymphocytic choriomeningitis virus.

NCF1 NCF1C NCF1B

1.99e-073204323328631
Pubmed

p47phox-Dependent Oxidant Signalling through ASK1, MKK3/6 and MAPKs in Angiotensin II-Induced Cardiac Hypertrophy and Apoptosis.

NCF1 NCF1C NCF1B

1.99e-073204334572995
Pubmed

B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production.

NCF1 NCF1C NCF1B

1.99e-073204325989352
Pubmed

Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase.

NCF1 NCF1C NCF1B

1.99e-073204317404617
Pubmed

Inhibition of NADPH oxidase by apocynin attenuates progression of atherosclerosis.

NCF1 NCF1C NCF1B

1.99e-073204323965970
Pubmed

Neutrophil-derived ROS contribute to oxidative DNA damage induction by quartz particles.

NCF1 NCF1C NCF1B

1.99e-073204320828610
Pubmed

NCF1-dependent production of ROS protects against lupus by regulating plasmacytoid dendritic cell development and functions.

NCF1 NCF1C NCF1B

1.99e-073204336853827
Cytoband15q15.3

STRC STRCP1 PPIP5K1

1.90e-0425206315q15.3
Cytoband1q41

CENPF CAPN8 MIA3 TP53BP2

2.28e-046620641q41
GeneFamilyCD molecules|Type II classical cadherins

CDH24 CDH22 CDH7 CDH8 CDH11 CDH12

2.22e-101313261186
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP25 ARHGAP23 ARHGAP10 ARHGAP5 ARHGAP27

3.13e-05501325721
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

MYO10 ARHGAP25 SKAP2 ARHGAP23 PLEKHG4 SH3BP2 CERT1 ARHGAP27

1.36e-042061328682
GeneFamilyProline rich and Gla domain containing

PRRG1 PRRG3

3.14e-04413221249
GeneFamilyAtaxins|Trinucleotide repeat containing

TNRC6B CASK KMT2D

7.78e-04251323775
GeneFamilySMAD family

SMAD2 SMAD6

1.44e-0381322750
GeneFamilySynaptotagmin like tandem C2 proteins

DOC2B RPH3A

2.29e-03101322822
GeneFamilyBasic leucine zipper proteins|BTB domain containing

ZBTB5 KLHL11 ZBTB44 ZBTB46 ZBTB3

3.03e-031341325861
CoexpressionPEREZ_TP53_TARGETS

ZNF777 MYO10 SPATA18 BLNK BCOR CABYR HOXC13 UMODL1 DQX1 ZBTB5 FAM83G PRAP1 BAIAP2 GNAS LDLRAD4 DOC2B ANK3 ARHGAP23 ARHGAP10 SHROOM2 CDH24 ARHGEF40 ADO LOXL1 CSPG4 LTF TMEM35A ARHGAP27 IL2RB DCLK1 SMAD6

5.04e-09120120531M4391
CoexpressionZHONG_PFC_C3_MICROGLIA

TANC2 JPH4 CSMD2 TENM2 BAIAP2 NPY CACNA1C ANK3 TACC2 GAREM2 LRP6 PRKCB SNCB CDH2 DCLK1 EPHA10

1.66e-0648820516M39104
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN

TANC2 ERCC4 SPEG HLF TNRC6B OTOS MGAT3 TULP4 AMOTL2 EHBP1 ABI1 COL11A2 ANK3 ARHGAP23 APBA2 SHROOM2 CERT1 TAMALIN ARHGAP5 MTMR4 ADO GAREM2 TMEM35A DCLK1

6.14e-06110220524M2369
CoexpressionKINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN

TANC2 TNRC6B TENM2 NEU1 GPNMB BAIAP2 GNAS AMOTL2 COL5A1 THBS3 DCLK1 SMAD6

1.52e-0533720512M13206
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

TANC2 FNBP1 JPH4 SPEG CSMD2 TENM2 TULP4 SLC24A2 CACNA1C MIA3 ANK3 ARHGAP23 APBA2 SHROOM2 CERT1 CASK CDH22 PRKCB PLCXD3 TMEM35A CDH8 DCLK1 CDH13

2.02e-05110620523M39071
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN

TANC2 ERCC4 SPEG HLF TNRC6B MGAT3 TULP4 AMOTL2 EHBP1 ABI1 COL11A2 ANK3 ARHGAP23 APBA2 SHROOM2 CERT1 TAMALIN ARHGAP5 MTMR4 ADO GAREM2 TMEM35A DCLK1

2.60e-05112420523MM1070
CoexpressionGSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_DN

SREBF2 IRF7 NEU1 PCYT2 SKAP2 LDLRAD4 BABAM2 LTA4H TNFAIP2

2.87e-051992059M5255
CoexpressionGSE27786_NKTCELL_VS_ERYTHROBLAST_DN

JPH4 PLPPR3 PTPRG NPY DOC2B ARRDC4 CDH22 EIF2AK1 SMAD6

2.98e-052002059M4867
CoexpressionGSE39382_IL3_VS_IL3_IL33_TREATED_MAST_CELL_DN

MYO10 INSM1 MCL1 IRF7 MIA3 ABI1 TNFAIP2 SLC25A28 CDH8

2.98e-052002059M9539
CoexpressionHALLMARK_APICAL_JUNCTION

SPEG SLC30A3 BAIAP2 SKAP2 SHROOM2 THBS3 FYB1 CDH8 CDH11

2.98e-052002059M5915
CoexpressionRODWELL_AGING_KIDNEY_UP

FNBP1 NCF1 ARHGAP25 GPNMB LDLRAD4 COL5A1 ARHGAP10 LOXL1 SLFN11 TNFAIP2 LTF FYB1 CDH11 ALPK2

4.40e-0550120514M5389
CoexpressionTAKAYAMA_BOUND_BY_AR

SKAP2 PPIP5K1 CDH2

5.43e-05102053M5315
CoexpressionZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_DN

LAPTM4B BLNK MGAT3 PRKCB SLFN11

5.90e-05532055M7602
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

FNBP1 PAG1 SPEF2 TNRC6B MCL1 DAXX SIT1 ADARB1 TBC1D10C CCSER2 ARHGAP25 GNAS TAF7 LDLRAD4 ABI1 APBA2 CBL UBLCP1 ZBTB44 KMT2D PRKCB DDX3Y SLFN11 FYB1 IL2RB TOR1AIP1

1.11e-04149220526M40023
CoexpressionLAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM

TANC2 SPEF2 TNRC6B NCKAP5 BCOR CSMD2 TENM2 PTPRG PCDH15 CACNA1C ARHGAP10 MLXIPL

1.18e-0441720512M39224
CoexpressionHAY_BONE_MARROW_STROMAL

EFS MYO10 SPATA18 NCKAP5 TENM2 PTPRG AMOTL2 COL5A1 TACC2 SNCAIP LOXL1 CORO6 CAVIN1 TMEM35A FAM20A CDH11 DCLK1

1.20e-0476720517M39209
CoexpressionGSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_DN

MYO10 SPATA18 IRF7 UNC93B1 CCDC57 TAMALIN ARHGAP27 SLC25A28

1.27e-041892058M4261
CoexpressionPGF_UP.V1_DN

USP9Y PTPRH CACNA1C COL11A2 RELB KMT2D LOXL1 DDX3Y

1.32e-041902058M2673
CoexpressionPTEN_DN.V2_DN

BCOR TACC2 KLHL11 ARHGEF40 KMT2D LOXL1 DDX3Y

1.38e-041432057M2758
CoexpressionGSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_20MIN_UP

JPH4 HEMGN MCL1 COL5A1 ARHGEF40 LOXL1 LRP6 CAVIN1

1.57e-041952058M6899
CoexpressionCLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN

COL5A1 LOXL1 CDH2 CDH11

1.57e-04352054M11788
CoexpressionCLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN

COL5A1 LOXL1 CDH2 CDH11

1.76e-04362054MM1212
CoexpressionGSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP

BLNK SREBF2 DAXX NEU1 ARHGAP25 BABAM2 ADO LTA4H

1.81e-041992058M5263
CoexpressionGSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_PLASMA_CELL_DAY7_UP

CENPF USP9Y CAPN8 SKAP2 VMP1 SH3BP2 RELB TOR1AIP1

1.87e-042002058M9360
CoexpressionGSE15330_WT_VS_IKAROS_KO_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN

EFS LAPTM4B SIT1 OTOS PCDH15 CERT1 ARHGAP5 GTF3C2

1.87e-042002058M7044
CoexpressionGSE42021_TREG_PLN_VS_CD24HI_TREG_THYMUS_UP

SLC30A3 RELB DDX3Y CAVIN1 TNFAIP2 SNCB TOP1 SMAD6

1.87e-042002058M9610
CoexpressionGSE14350_IL2RB_KO_VS_WT_TEFF_DN

HEMGN NAGS HOXC13 SH3BP2 TACC2 SHROOM2 TMEM35A IL2RB

1.87e-042002058M3424
CoexpressionGSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_UP

HLF NEU1 OTOS FER PCDH15 SCARF1 LTF SLC25A28

1.87e-042002058M7980
CoexpressionGSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP

FNBP1 SIK2 ARHGAP10 PHF12 SH3BP2 VXN ZNF335 SLFN11

1.87e-042002058M6524
CoexpressionGSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_HIGH_MONOCYTE_UP

MYO10 NCF1 LAPTM4B SIT1 COL5A1 ANK3 TNFAIP2 SMAD6

1.87e-042002058M9060
CoexpressionGSE11924_TH1_VS_TH17_CD4_TCELL_UP

EXTL3 OTOS PRAP1 DCPS SH3BP2 BABAM2 MLXIPL DCLK1

1.87e-042002058M3161
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCF1 UNC93B1 GPNMB SKAP2 PRR15L PRKCB PLCXD3 TNFAIP2 FYB1 DCLK1 ALPK2

5.25e-10172206113f784aed340b50ddbec3f7dc0a5279180d38a2bb
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

NCKAP5 TENM2 MYO18B CACNA1C ANK3 TACC2 PLCXD3 CDH2 PRDM16 ALPK2 CDH13

1.51e-0919020611fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCF1 BLNK IRF7 SIT1 SHD UNC93B1 LDLRAD4 FUZ PRKCB MYBL2

1.91e-08188206101f820cb19eb0e15f0eb69d07e457072bbdad8ecb
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

NCKAP5 TENM2 MYO18B ANK3 TACC2 PLCXD3 CDH2 PRDM16 ALPK2 CDH13

2.01e-08189206109c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO10 COL6A5 ADARB1 PCDH15 CACNA1C COL5A1 DNAI3 DYNC1LI1 FAM20A CDH11

2.01e-08189206102a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCF1 BLNK IRF7 SIT1 SHD UNC93B1 LDLRAD4 FUZ PRKCB MYBL2

2.11e-0819020610c44aae2e0d3cc84a187e12917fd8c2d7483f41d8
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCF1 BLNK IRF7 SIT1 SHD UNC93B1 LDLRAD4 FUZ PRKCB MYBL2

2.11e-0819020610705489ebbaf3d8e643498c3e507742114475fc55
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

NCKAP5 TENM2 MYO18B CACNA1C ANK3 TACC2 PLCXD3 CDH2 PRDM16 ALPK2

2.45e-0819320610dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EXPH5 TENM2 GPNMB STRC EHBP1 COL5A1 GRIN2A KLHL11 PLCXD3

5.52e-0815820698c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EXPH5 TENM2 GPNMB STRC EHBP1 COL5A1 GRIN2A KLHL11 PLCXD3

5.52e-081582069f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

DLGAP2 CSMD2 TENM2 PCDH15 MYO18B RPH3A CDH8 CDH12 CDH13

5.83e-0815920695335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellLV-03._Atrial_Cardiomyocyte|LV / Chamber and Cluster_Paper

HEMGN PCDH15 PRRG3 MYO18B CACNA1C ANK3 RPH3A CDH13

9.13e-0812020683b77bd0e3630cdd45001cecf5e47660a90ebc92e
ToppCell390C-Myeloid-Dendritic-pDC|390C / Donor, Lineage, Cell class and subclass (all cells)

NCF1 BLNK IRF7 SHD UNC93B1 BAIAP2 LDLRAD4 TAMALIN MYBL2

9.36e-0816820695a2e7a52b7330dce30823695a7b9b26bc47a69ce
ToppCellTracheal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NCF1 INSM1 IRF7 SHD LDLRAD4 TAMALIN PRKCB ALPK2 MYBL2

9.36e-081682069c34dd4a9c54d8e9c8f118e6a3816548890cb0746
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCF1 HEMGN UNC93B1 GPNMB LOXL1 LTA4H CAVIN1 LTF MYBL2

1.33e-071752069b4ff5a74ad22addbdd848dde9ba93d63a0611543
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCF1 HEMGN UNC93B1 GPNMB LOXL1 LTA4H CAVIN1 LTF MYBL2

1.33e-07175206927a8c6e398638ccdee90c44e2ca6f59acc206cbc
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCF1 INSM1 BLNK IRF7 SIT1 SHD UNC93B1 PRKCB MYBL2

1.69e-0718020696a2366d76276452141db1bd93013a9503525f574
ToppCellLV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

TENM2 PRRG3 MYO18B CACNA1C RPH3A PLCXD3 CDH2 CDH13

1.70e-071302068a3e12984fb61311e49cc76c59f74f4dffc48faa1
ToppCelltumor_Lung-Myeloid_cells-pDCs|tumor_Lung / Location, Cell class and cell subclass

INSM1 BLNK IRF7 SHD UNC93B1 LDLRAD4 FUZ PRKCB MYBL2

1.77e-071812069c864ffeb9234b8c29754afc91c85a972889617f4
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLF COL6A5 SHD SLC6A9 CSPG4 TMEM35A TMC5 CDH2 MYBL2

1.85e-071822069c84f44391932080df31c8765e363c3dff64b2bd1
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

TENM2 MYO18B CACNA1C ANK3 TACC2 PLCXD3 ANKRD34C CDH2 CDH13

2.13e-0718520696baccb26f999145e51b91d94315bf8d4655bef31
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FNBP1 PAG1 TNRC6B TBC1D10C ARHGAP25 APBA2 PRKCB FYB1 IL2RB

2.23e-0718620699d576dce2c5deefef1adda16c6da7055c8d57f8f
ToppCellmyeloid-Dendritic_cell-Plasmacytoid_dendritic_cell|Dendritic_cell / Lineage, cell class and subclass

PAG1 NCF1 BLNK IRF7 SIT1 SHD LDLRAD4 PRKCB MYBL2

2.23e-071862069858134580a09ed8a5eb6d6413d8ca9265904dfc1
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

MYO10 COL6A5 ADARB1 PTPRG PCDH15 CACNA1C COL5A1 CDH11 CDH13

2.33e-071872069e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellrenal_cortex_nuclei-Adult_normal_reference|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

MYO10 SIK2 BAIAP2 LDLRAD4 ANK3 ARHGAP10 SH3BP2 TACC2 FAM135B

2.55e-071892069a48df46274d51e84ffb40264646de7346104efb9
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

NCKAP5 TENM2 MYO18B CACNA1C ANK3 TACC2 CDH2 ALPK2 CDH13

2.55e-0718920690a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

TENM2 MYO18B CACNA1C TACC2 PLCXD3 CDH2 PRDM16 ALPK2 CDH13

2.55e-0718920695e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

ADARB1 PTPRG PCDH15 CACNA1C COL5A1 ARHGAP10 CDH11 DCLK1 CDH13

2.66e-0719020693a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

NCKAP5 TENM2 MYO18B CACNA1C ANK3 TACC2 CDH2 ALPK2 CDH13

2.66e-07190206993c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellCOVID-19-lung-CD4+_Treg|COVID-19 / Disease (COVID-19 only), tissue and cell type

FNBP1 PAG1 TBC1D10C ARHGAP25 LDLRAD4 ANK3 CASK PRKCB FYB1

2.79e-0719120695a4ad5ae5c2dbfb225158cb598ef649c26a48350
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

NCKAP5 TENM2 MYO18B CACNA1C ANK3 TACC2 CDH2 ALPK2 CDH13

2.79e-0719120695d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

NCKAP5 TENM2 MYO18B ANK3 TACC2 PLCXD3 CDH2 ALPK2 CDH13

2.91e-071922069ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO10 ADARB1 TENM2 PTPRG PCDH15 CACNA1C COL5A1 CORO6 CDH11

3.04e-07193206999525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO10 ADARB1 TENM2 PTPRG PCDH15 CACNA1C COL5A1 CORO6 CDH11

3.04e-071932069b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellnucseq-Immune-Immune_Myeloid-pMON-pMON|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PAG1 ARHGAP25 VMP1 SH3BP2 CBL PRKCB TNFAIP2 ARHGAP27 FYB1

3.18e-071942069e237384b02be460d44eeada3026a5691c66f6fc1
ToppCellnucseq-Immune-Immune_Myeloid-pMON|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PAG1 ARHGAP25 VMP1 SH3BP2 CBL PRKCB TNFAIP2 ARHGAP27 FYB1

3.18e-0719420690bc83ae79873a5e473e6e1e3111924cd003986a1
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

NCKAP5 MYO18B CACNA1C ANK3 TACC2 DNAI3 CDH2 ALPK2 CDH13

3.18e-07194206989812fb164065041357bb37a3c2d87028ec3de4e
ToppCellmedial-2-Hematologic-Plasmacytoid_Dendritic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

INSM1 BLNK IRF7 SIT1 SHD UNC93B1 PRKCB NCF1C MYBL2

3.18e-071942069d58be6454a0795d6771036a1620553a153861615
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

NCKAP5 TENM2 MYO18B CACNA1C ANK3 TACC2 CDH2 ALPK2 CDH13

3.18e-071942069c3535f7cc0076653c72db582047cff053c322397
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYO10 ADARB1 TENM2 PTPRG PCDH15 CACNA1C COL5A1 PRKCB CDH11

3.18e-071942069011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellmedial-Hematologic-Plasmacytoid_Dendritic|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

INSM1 BLNK IRF7 SIT1 SHD UNC93B1 PRKCB NCF1C MYBL2

3.18e-071942069bb36274d6fe2d18c545a17d3809f331586502d01
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCF1 BLNK IRF7 SIT1 SHD UNC93B1 LDLRAD4 PRKCB MYBL2

3.18e-0719420693f9e4a8e5699bc379e8a0d337e0daef09632e71c
ToppCellmedial-Hematologic-Plasmacytoid_Dendritic-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

INSM1 BLNK IRF7 SIT1 SHD UNC93B1 PRKCB NCF1C MYBL2

3.18e-0719420690117cd68750153fd6b8978c8b4ce3589486d2b5f
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

NCKAP5 TENM2 MYO18B CACNA1C ANK3 TACC2 PLCXD3 CDH2 ALPK2

3.32e-07195206975fc81bddb246dca3b437fb60827b1d4fe416405
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO10 INSM1 TULP4 SLC24A2 MIA3 MLXIPL PRKCB DDX3Y CDH2

3.32e-0719520697796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EFS GPNMB COL5A1 ANK3 PLEKHG4 THBS3 CSPG4 CAVIN1 DCLK1

4.11e-072002069747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CSMD2 TENM2 MYO18B TMEM61 ARHGAP10 TACC2 SLC6A9 CSPG4 CORO6

4.11e-0720020699169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EFS GPNMB COL5A1 ANK3 PLEKHG4 THBS3 CSPG4 CAVIN1 DCLK1

4.11e-072002069de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BLNK IRF7 SIT1 SHD COL11A2 APEX1 RELB MYBL2

9.54e-0716320683087224d3f16f5d3aecc3e1e4366220231afe31f
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCF1 BLNK IRF7 SIT1 SHD LDLRAD4 FUZ MYBL2

1.05e-061652068e2a70dd5870fe8708bf630ed3e6eb3f295df0cdf
ToppCell(3)_DC_plasmacytoid|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

NCF1 BLNK IRF7 SHD LDLRAD4 FUZ TAMALIN MYBL2

1.20e-0616820688a913db9b2a1a4ff96fb139734a3834e6aa263f1
ToppCellnormal-na-Lymphocytic_T-T4_em-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

FNBP1 PAG1 HLF CCSER2 ANK3 DDX3Y CAVIN1 FYB1

1.37e-06171206861318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-pDC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NCF1 BLNK IRF7 TBC1D10C LDLRAD4 PRKCB SLC25A28 MYBL2

1.56e-0617420684120656e6d6cf5435a248326b5fdbdc7b22137af
ToppCellRV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

TENM2 MYO18B CACNA1C TACC2 PRDM16 ALPK2 CDH13

1.63e-0612220671cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCellILEUM-inflamed-(3)_pDC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IRF7 SHD UNC93B1 BAIAP2 LDLRAD4 FUZ TAMALIN MYBL2

1.70e-061762068b9f847dd55703e413f3cd815eef5724fffaf13b3
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCF1 INSM1 BLNK IRF7 SIT1 SHD PRKCB MYBL2

1.93e-0617920684808469096cd6bec2bdfcf4fc55aa324757600c3
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCF1 INSM1 BLNK IRF7 SIT1 SHD PRKCB MYBL2

1.93e-0617920684d55718c6afd8a038d93cc77b9b08171dab9976f
ToppCellfacs-Kidney-nan-24m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFS HEMGN COL6A5 COL5A1 THBS3 LOXL1 PPIP5K1 CDH11

2.01e-061802068f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO10 COL6A5 ADARB1 TENM2 PCDH15 CACNA1C DNAI3 CDH11

2.09e-0618120689ede19228ba5c0668a9c06c915510b95585216ef
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP2 BCOR PCDH15 GRIN2A MLXIPL CDH22 ALPK2 CDH13

2.09e-061812068c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellmetastatic_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

BLNK IRF7 SIT1 SHD LDLRAD4 DCPS FUZ MYBL2

2.18e-06182206802e04294fce12591c32d7bd0e866a000ad1f836e
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

NCKAP5 TENM2 MYO18B CACNA1C ANK3 TACC2 CDH2 ALPK2

2.18e-061822068287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellmyeloid-Dendritic_cell-Plasmacytoid_dendritic_cell|World / Lineage, cell class and subclass

BLNK IRF7 SHD DQX1 UNC93B1 LDLRAD4 SNCAIP MYBL2

2.36e-06184206811619778bc773ecd1a9867330be04deaf324f31e
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

TENM2 MYO18B CACNA1C ANK3 TACC2 PLCXD3 CDH2 CDH13

2.36e-061842068ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

TENM2 MYO18B CACNA1C TACC2 PLCXD3 CDH2 ALPK2 CDH13

2.46e-061852068549eeb521c3985bff396ea0f202db21822efa51f
ToppCellILEUM-inflamed-(3)_MNP-(3)_pDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

BLNK IRF7 SHD LDLRAD4 DCPS FUZ PRKCB MYBL2

2.46e-061852068308a98f111895071d8772bc010554471cc12fab2
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INSM1 BLNK IRF7 SHD LDLRAD4 TAMALIN PRKCB MYBL2

2.56e-0618620680096a61b1841784c913752b4f3639200446cc02c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FNBP1 PAG1 TNRC6B TBC1D10C ARHGAP25 APBA2 PRKCB FYB1

2.56e-061862068bd3bd022b575d9b0ef90d50a5cb874085a827b77
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INSM1 BLNK IRF7 SHD LDLRAD4 TAMALIN PRKCB MYBL2

2.56e-0618620689e159ad7289dcae2ec7ce655df746f46801b81d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NCKAP5 EHBP1 ANK3 FAM135B TNFAIP2 CDH2 DCLK1 ALPK2

2.56e-061862068b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INSM1 BLNK IRF7 SHD LDLRAD4 TAMALIN PRKCB MYBL2

2.56e-0618620686345777847960c71a2ba3ce5a49c72c34ebd0e73
ToppCellcellseq-Immune-Immune_Myeloid-Myeloid_Dendritic-pDC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NCF1 BLNK IRF7 SIT1 SHD LDLRAD4 PRKCB MYBL2

2.56e-061862068d23c3318937492d7d665bec14253124c49181b5a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FNBP1 PAG1 TNRC6B TBC1D10C ARHGAP25 APBA2 PRKCB FYB1

2.56e-061862068924cc357b4c4ce8e9b05773bdab544f0b65474cc
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPEG CSMD2 TENM2 CACNA1C TMEM61 ARHGAP10 SLC6A9 CSPG4

2.56e-061862068a95744b8649096bd7cfc3591a02841fa411085b3
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

NCKAP5 TENM2 TACC2 PLCXD3 CDH2 PRDM16 ALPK2 CDH13

2.67e-06187206878cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

DLGAP2 MYO10 EXPH5 LAPTM4B EXTL3 ANK3 GRIN2A TMC5

2.77e-061882068b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FNBP1 PAG1 TBC1D10C ARHGAP25 APBA2 PRKCB FYB1 IL2RB

3.00e-0619020685b4b3eed7aa798bb7e3c5e968c8dc4144e377a5f
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

TENM2 MYO18B CACNA1C TACC2 PLCXD3 CDH2 PRDM16 CDH13

3.00e-061902068de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FNBP1 PAG1 TBC1D10C ARHGAP25 APBA2 PRKCB FYB1 IL2RB

3.00e-06190206807ea0578ca0561077557203ae660530f53fc4067
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NCKAP5 PCDH15 EHBP1 ANK3 FAM135B MLXIPL CDH2 ALPK2

3.12e-0619120681c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellhematopoetic_progenitors-CD34+_CLP|World / Lineage and Cell class

PAG1 BLNK UMODL1 LDLRAD4 NPY COL5A1 APEX1 CDH2

3.12e-06191206832f2537c97c9984629d61c6f34a337f555146ad4
ToppCellCOVID-19-T_cells-CD4+_T_cells|COVID-19 / group, cell type (main and fine annotations)

FNBP1 PAG1 CCSER2 ANK3 APBA2 CASK PRKCB FYB1

3.12e-0619120680646cca78e24aeb6baa9934d3c439b797c567997
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BLNK CAPN8 FER ANK3 TACC2 TMC5 FAM20A PRDM16

3.12e-0619120683e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NCKAP5 PCDH15 EHBP1 ANK3 FAM135B MLXIPL CDH2 ALPK2

3.12e-0619120683c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellhuman_hepatoblastoma-Inflammatory_Monocytes|World / Sample and Cell Type and Tumor Cluster (all cells)

TANC2 PAG1 ARHGAP25 GPNMB ARHGAP10 PRKCB TNFAIP2 FYB1

3.12e-0619120683b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

TENM2 MYO18B CACNA1C ANK3 TACC2 PLCXD3 CDH2 CDH13

3.12e-06191206825f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EXPH5 INSM1 PDX1 TULP4 SLC24A2 MLXIPL PRKCB CDH8

3.24e-0619220685b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

HLF USP9Y CAPN8 PTPRG ANK3 TACC2 MLXIPL FAM20A

3.24e-06192206806013a07e3a873b1d1c0451643c528593ac32a9c
ToppCellproximal-Hematologic-Plasmacytoid_Dendritic|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCF1 BLNK IRF7 SHD FUZ TAMALIN PRKCB MYBL2

3.24e-061922068faead5875a54fe8f1848ae36008aae4c0f7cb1c7
ToppCellproximal-3-Hematologic-Plasmacytoid_Dendritic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCF1 BLNK IRF7 SHD FUZ TAMALIN PRKCB MYBL2

3.24e-06192206886938c7d2bb1a7afb2b83828ca33dd137d366ec6
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INSM1 SLC24A2 MIA3 TACC2 ARHGAP5 MLXIPL PRKCB CDH2

3.24e-0619220681304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCellproximal-Hematologic-Plasmacytoid_Dendritic-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCF1 BLNK IRF7 SHD FUZ TAMALIN PRKCB MYBL2

3.24e-061922068e3be395a995dc8c0ebdae754057cfa59a270cae0
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A5 ADARB1 PCDH15 CACNA1C COL5A1 DNAI3 FAM20A CDH11

3.24e-061922068deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

COL6A5 ADARB1 TENM2 PCDH15 CACNA1C COL5A1 CDH11 CDH13

3.37e-061932068ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

PAG1 MYO10 COL6A5 NCKAP5 ADARB1 CACNA1C CDH11 CDH13

3.37e-0619320685896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

MYO10 ADARB1 TENM2 PTPRG PCDH15 CACNA1C COL5A1 CDH11

3.37e-061932068acad568621ed677031797b8c2e34dafea798d681
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCF1 BLNK IRF7 SIT1 SHD UNC93B1 PRKCB MYBL2

3.50e-0619420685250736b608001fb73aa74dee8cb8465a1d2f372
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INSM1 SLC24A2 MIA3 TACC2 ARHGAP5 MLXIPL PRKCB CDH2

3.50e-06194206892b39a935e8c577eb1123d706d168fa13cf3344c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FNBP1 PAG1 SIT1 TBC1D10C ARHGAP25 APBA2 PRKCB FYB1

3.50e-061942068633fe72cc8a489abde12428e326478409ca03263
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FNBP1 PAG1 SIT1 TBC1D10C ARHGAP25 APBA2 PRKCB FYB1

3.50e-06194206887a86df0b542f287b0b20f4a4b1a37002271671d
ComputationalMetal ion (zinc) binding.

ACE PTPRG YY1 LOXL1 LTA4H LTF

1.68e-05451326MODULE_280
DrugVanadates

TANC2 PAG1 MYO10 EXPH5 HLF SREBF2 MCL1 NCKAP5 USP9Y ADARB1 TENM2 HOXC13 PTPRG GPNMB SKAP2 ARHGAP23 PLEKHG4 VXN APBA2 CERT1 CASK KLHL11 ZBTB44 LOXL1 DDX3Y PPIP5K1 CAVIN1 SLFN11 TNFAIP2 CDH13

1.71e-06130220330ctd:D014638
DrugChloroprene

MYO10 SPATA18 BLNK TNRC6B IRF7 ADARB1 TBC1D10C CLCA1 TULP4 CCSER2 PRRG3 BAIAP2 GNAS DOC2B CACNA1C COL5A1 ABI1 CBL SHROOM2 DNAI3 ARHGAP5 CDH22 LOXL1 LRP6 PRKCB FAM20A FYB1 CDH2 TOR1AIP1 CDH11

3.44e-06134820330ctd:D002737
Diseasechronic granulomatous disease (implicated_via_orthology)

NCF1 NCF1C NCF1B

3.08e-0652013DOID:3265 (implicated_via_orthology)
Diseaseautosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)

STRC STRCP1

4.62e-0522012DOID:0110471 (implicated_via_orthology)
Diseasereaction time measurement

HLF NCKAP5 TENM2 LDLRAD4 ARHGAP23 PRR15L TACC2 GRIN2A RPH3A MLXIPL KMT2D ANO7 CDH2 CDH7 CDH13

4.98e-0565820115EFO_0008393
Diseaserheumatoid arthritis (implicated_via_orthology)

NCF1 NCF1C NCF1B

6.55e-05122013DOID:7148 (implicated_via_orthology)
Diseasecolorectal adenoma

BLNK CSMD2 NPY CDH13

7.32e-05332014EFO_0005406
Diseaseurate measurement, bone density

FNBP1 DLGAP2 ERCC4 COL6A5 TENM2 SNX19 PTPRG ARHGAP25 SKAP2 LDLRAD4 COL5A1 DCLK1 CDH12 CDH13

9.66e-0561920114EFO_0003923, EFO_0004531
DiseaseIGF-1 measurement

INSM1 HLF SREBF2 SLC30A3 BAIAP2 GNAS VMP1 BABAM2 MLXIPL ZBTB46 GAREM2 PLCXD3

1.42e-0448820112EFO_0004627
Diseaseprogression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian serous carcinoma

MYO18B PRDM16 CDH7 DCLK1

1.91e-04422014EFO_0004920, EFO_1001516, GO_0097328, MONDO_0009354
Diseasefasting blood glucose measurement, response to metformin

BABAM2 CDH13

2.75e-0442012EFO_0004465, GO_1901558
DiseaseKidney Failure, Chronic

NCF1 SREBF2 ACE MLXIPL

3.22e-04482014C0022661
DiseaseSchizophrenia

DLGAP2 PAG1 SREBF2 CSMD2 ACE SLC30A3 ADARB1 GNAS NPY CACNA1C ANK3 APBA2 GRIN2A SLC6A9 SNCB DCLK1

3.87e-0488320116C0036341
Diseaselung non-small cell carcinoma (is_implicated_in)

MCL1 CBL KMT2D PRKCB LTF CDH13

3.93e-041392016DOID:3908 (is_implicated_in)
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

KARS1 PCDH15 STRC COL11A2

4.07e-04512014cv:CN043650
DiseaseNeurodevelopmental Disorders

TANC2 SMC1A TNRC6B CERT1 CASK

4.46e-04932015C1535926
Diseasekidney injury

DLGAP2 CDH12

4.56e-0452012EFO_0009833
Diseasestatus epilepticus (biomarker_via_orthology)

NPY ANK3 APEX1 GRIN2A PRKCB

6.22e-041002015DOID:1824 (biomarker_via_orthology)
Diseasediastolic blood pressure, systolic blood pressure

SPEG TNRC6B MCL1 SNX19 FER SKAP2 CACNA1C ANK3 ZBTB44 LOXL1 CDH2 CDH13 SMAD6

7.32e-0467020113EFO_0006335, EFO_0006336
Diseaserisk-taking behaviour

ERCC4 TENM2 TULP4 SLC24A2 PCDH15 EHBP1 CACNA1C ABI1 GRIN2A THBS3 CDH22 MTX1 CDH8 CDH13

8.02e-0476420114EFO_0008579
Diseasecongestive heart failure (is_implicated_in)

SMC1A CBL YY1

8.07e-04272013DOID:6000 (is_implicated_in)
DiseaseEpilepsy

TANC2 SMC1A NPY GRIN2A CERT1

9.19e-041092015C0014544
Diseasecancer antigen 15.3 measurement

THBS3 MTX1

9.48e-0472012EFO_0010585
Disease3- 4-hydroxyphenyl lactate measurement

CCDC57 CDH2

9.48e-0472012EFO_0021008
Diseasedaytime rest measurement

DLGAP2 ZBTB5 BAIAP2 GRIN2A ADO PRKCB CDH2 CDH13

9.89e-042952018EFO_0007828
Diseasecervical cancer (is_implicated_in)

APEX1 CDH13 SMAD2

1.10e-03302013DOID:4362 (is_implicated_in)
Diseasewhite matter hyperintensity measurement

SPEF2 MCL1 TENM2 GRIN2A YY1 SNCAIP PRDM16 CDH11

1.15e-033022018EFO_0005665
DiseaseMalignant neoplasm of breast

PRRG1 CENPF SPATA18 SREBF2 GPNMB EHBP1 TACC2 SHROOM2 UBLCP1 THBS3 KMT2D CAVIN1 ZBTB3 CDH2 TOR1AIP1 TOP1 TP53BP2

1.15e-03107420117C0006142
DiseaseMale sterility due to Y-chromosome deletions

USP9Y DDX3Y

1.26e-0382012C2931163
Diseaseplacental insufficiency (biomarker_via_orthology)

PDX1 GRIN2A

1.26e-0382012DOID:3891 (biomarker_via_orthology)
DiseasePartial chromosome Y deletion

USP9Y DDX3Y

1.26e-0382012C1507149
Diseasepantothenate measurement

SLC30A3 TENM2

1.26e-0382012EFO_0021034
DiseaseMajor Depressive Disorder

HLF IRF7 ACE NPY CACNA1C PRKCB CDH7

1.44e-032432017C1269683
Diseaseresponse to xenobiotic stimulus

CSMD2 PCDH15 CDH22 CDH2 CDH12 CDH13

1.60e-031822016GO_0009410
Diseaseangiotensin-converting enzyme measurement

TANC2 ACE

1.61e-0392012EFO_0006515
Diseaseureteral obstruction (implicated_via_orthology)

ACE RELB

1.61e-0392012DOID:5199 (implicated_via_orthology)
Diseasemarginal zone B-cell lymphoma, multiple sclerosis

VMP1 ZBTB46

1.61e-0392012EFO_1000630, MONDO_0005301
DiseaseSAPHO syndrome

APBA2 YY1 LOXL1

1.74e-03352013EFO_1001164
DiseaseNonsyndromic genetic hearing loss

KARS1 PCDH15 STRC COL11A2

1.83e-03762014cv:C5680182
Diseasecognitive function measurement

TANC2 ERCC4 CAPN8 MGAT3 TULP4 BAIAP2 MYO18B LDLRAD4 NPY CACNA1C COL5A1 GRIN2A FAM135B KMT2D ZNF335 CDH2 CDH7 CDH8 DCLK1 CDH13

1.97e-03143420120EFO_0008354
DiseaseUterine leiomyoma, estrogen-receptor negative breast cancer

EXPH5 TNRC6B

2.00e-03102012EFO_1000650, HP_0000131
DiseaseUnipolar Depression

HLF IRF7 ACE NPY CACNA1C PRKCB CDH7

2.07e-032592017C0041696
Diseasebipolar disorder

DLGAP2 ERCC4 HLF SNX19 CACNA1C ANK3 GRIN2A BABAM2 KMT2D ADO CDH13

2.13e-0357720111MONDO_0004985
DiseaseNonsyndromic Deafness

KARS1 PCDH15 STRC COL11A2

2.31e-03812014C3711374
Diseaseplatelet crit

EXPH5 HEMGN PTPRH TULP4 DQX1 ARHGAP25 LDLRAD4 VMP1 CACNA1C CBL SCARF1 ARHGEF40 ADO FYB1 PRDM16

2.33e-0395220115EFO_0007985
DiseaseEpilepsy, Cryptogenic

SMC1A NPY GRIN2A CERT1

2.42e-03822014C0086237
DiseaseAwakening Epilepsy

SMC1A NPY GRIN2A CERT1

2.42e-03822014C0751111
DiseaseAura

SMC1A NPY GRIN2A CERT1

2.42e-03822014C0236018
DiseaseAlcoholic Intoxication, Chronic

ACE NPY GRIN2A CDH8 CDH11 CDH12 CDH13

2.51e-032682017C0001973
Diseasecolonic neoplasm

TNRC6B COL5A1 PHF12

2.74e-03412013EFO_0004288
Diseasecup-to-disc ratio measurement

PLPPR3 AMOTL2 ANK3 CCDC57 BABAM2 SNCAIP LOXL1 PRDM16 DCLK1

2.89e-034302019EFO_0006939
Diseaseextrapulmonary tuberculosis

ZBTB5 CACNA1C

2.91e-03122012MONDO_0000368
Disease3-hydroxy-1-methylpropylmercapturic acid measurement

SPEF2 LDLRAD4 NPY EHBP1 YBEY PHF12 FAM20A CDH13

2.98e-033522018EFO_0007015
DiseaseColorectal Neoplasms

CABYR GPNMB GRIN2A CDH22 PRKCB CDH7 DCLK1

3.01e-032772017C0009404
Diseasedescending aortic diameter

FER LDLRAD4 ARHGEF40 LOXL1

3.12e-03882014EFO_0021788
Diseasecarpal tunnel syndrome

COL11A2 THBS3 LOXL1 SMAD6

3.25e-03892014EFO_0004143
Diseaseextracellular matrix protein 1 measurement

MCL1 MIA3

3.43e-03132012EFO_0008126
Diseaseurate measurement

HLF SLC30A3 GNAS MYO18B VMP1 BABAM2 APLF RPH3A MLXIPL THBS3 CSPG4 MTX1 NAIF1 TOP1

3.45e-0389520114EFO_0004531
DiseaseCalcium channel blocker use measurement

ACE GNAS CACNA1C ZBTB46 THBS3 MTX1

3.50e-032132016EFO_0009930
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

ERCC4 BLNK TENM2 TULP4 PCDH15 BAIAP2 ABI1 TACC2 GRIN2A FAM135B CDH22 CDH8 CDH13

3.51e-0380120113EFO_0003888, EFO_0007052, MONDO_0002491
DiseaseGastric Adenocarcinoma

SPEG DCLK1 EPHA10

3.58e-03452013C0278701
Diseaseresting heart rate

SPEG CACNA1C ARHGAP10 ARHGEF40 CDH2

3.62e-031492015EFO_0004351
DiseaseDepressive disorder

CSMD2 ACE NPY CACNA1C GRIN2A LTA4H CDH13

3.80e-032892017C0011581
DiseaseSeizures

TANC2 SMC1A KARS1 PCYT2 NPY APEX1

3.92e-032182016C0036572
Diseasetriacylglycerol 46:2 measurement

GTF3C2 ANKRD34C

3.98e-03142012EFO_0010402
Diseasesulfate measurement

DNAI3 UBLCP1

3.98e-03142012EFO_0007864
Diseaseserum gamma-glutamyl transferase measurement

PDX1 MCL1 SLC30A3 TENM2 SLC24A2 EHBP1 ARHGAP10 BABAM2 MLXIPL ZBTB46 TNFAIP2 SLC25A28 TOP1 ALPK2

4.15e-0391420114EFO_0004532
DiseaseMale sterility

ACE CBL KMT2D

4.30e-03482013C0917731
DiseaseMale infertility

ACE CBL KMT2D

4.30e-03482013C0021364
DiseaseSubfertility, Male

ACE CBL KMT2D

4.30e-03482013C0848676
Diseaseperiodontitis

TENM2 NPY FAM135B MLXIPL CDH2 CDH13

4.37e-032232016EFO_0000649
Diseasealcohol use disorder measurement, alcohol consumption measurement

PCDH15 EHBP1 CACNA1C MLXIPL

4.42e-03972014EFO_0007878, EFO_0009458
Diseasecancer biomarker measurement

FAM135B PPIP5K1

4.57e-03152012EFO_0005127
Diseaseresponse to olanzapine

CACNA1C CDH13

4.57e-03152012GO_0097333
Diseasetotal cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement

SLC30A3 CERT1 MLXIPL

5.10e-03512013EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
DiseasePsychotic Disorders

ADARB1 CACNA1C ANK3 SLC6A9

5.10e-031012014C0033975
DiseaseBarrett Epithelium

MCL1 CDH13

5.20e-03162012C1258085
DiseaseSpermatogenic Failure, Nonobstructive, Y-Linked

USP9Y DDX3Y

5.20e-03162012C1839071
Diseasecutaneous psoriasis measurement, psoriasis

UBLCP1 ADO

5.20e-03162012EFO_0000676, EFO_0007773
DiseaseSpermatogenic failure, Y-linked, 2

USP9Y DDX3Y

5.20e-03162012cv:C1839071
DiseaseSPERMATOGENIC FAILURE, Y-LINKED, 2

USP9Y DDX3Y

5.20e-03162012415000
DiseaseBarrett Esophagus

MCL1 CDH13

5.20e-03162012C0004763
DiseaseWeight Gain

MYO10 ACE VPS13D CAVIN1

5.28e-031022014C0043094
DiseaseDisease Exacerbation

SREBF2 APEX1 YY1 CDH2 TOP1

5.56e-031652015C0235874
DiseaseBipolar Disorder

ACE ADARB1 CACNA1C ANK3 GRIN2A PLCXD3 IL2RB CDH7 DCLK1

5.65e-034772019C0005586
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

COL5A1 SMAD2 SMAD6

5.68e-03532013C4707243
Diseasediet measurement

DLGAP2 INSM1 TNRC6B ADARB1 TENM2 CAPN8 SIK2 ANK3 APLF MLXIPL ZBTB46 CDH22 PRKCB PRDM16 CDH13

5.69e-03104920115EFO_0008111
Diseaseplatelet component distribution width

HLF HEMGN NEU1 PTPRH GNAS VMP1 CACNA1C MLXIPL ADO CAVIN1 FYB1 PRDM16

5.84e-0375520112EFO_0007984
Diseasetriacylglycerol 56:9 measurement

BCOR PRKCB

5.87e-03172012EFO_0010436
DiseaseLimb Deformities, Congenital

CACNA1C COL11A2

5.87e-03172012C0206762
Diseasereticulocyte measurement

HEMGN TNRC6B PLPPR3 MGAT3 PTPRH ARHGAP25 AMOTL2 CBL SCARF1 KLHL11 MLXIPL LTN1 EIF2AK1 PRDM16 MYBL2

5.89e-03105320115EFO_0010700
DiseaseSmall cell carcinoma of lung

INSM1 FER MYO18B

5.98e-03542013C0149925
Diseaseapolipoprotein B measurement

NAGS EHBP1 TMEM61 RELB CERT1 BABAM2 RPH3A MLXIPL GTF3C2 DYNC1LI1 TOP1

6.01e-0366320111EFO_0004615
Diseasefamilial hyperlipidemia

RELB CERT1 BABAM2 MLXIPL

6.05e-031062014MONDO_0001336
DiseaseQRS-T angle

SPEG MYO18B FAM135B CDH13

6.05e-031062014EFO_0020097
Diseasetriacylglycerol 52:2 measurement

NCKAP5 MLXIPL GTF3C2

6.30e-03552013EFO_0010414
Diseaseremnant cholesterol measurement

EHBP1 RELB CERT1 TOP1

6.45e-031082014EFO_0010815
Diseaseresponse to bronchodilator, FEV/FEC ratio

DLGAP2 ERCC4 TENM2 PTPRH PCDH15 GNAS CACNA1C FAM135B PRKCB CDH2 PRDM16 CDH13

6.53e-0376620112EFO_0004713, GO_0097366
Diseaseovarian cancer (is_implicated_in)

APEX1 CDH13 SMAD2

6.62e-03562013DOID:2394 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
VPPTATEEQYAGSDP

PTPRG

676

P23470
EGGAPDFPVEYSERP

UMODL1

926

Q5DID0
EFPQPDFPDDYNLGD

YBEY

76

P58557
PQPSKGEELPTYEEA

AMOTL2

96

Q9Y2J4
GSPAQGPIPYLDDDI

DISP3

656

Q9P2K9
PCGEDYEEEGPELAP

ARHGEF40

1011

Q8TER5
GQDETDDRPECPYGP

APLF

411

Q8IW19
ENDLYDLDIQPGPDP

ANKRD34C

376

P0C6C1
YPDAEAPEPSSAGAQ

CAVIN1

16

Q6NZI2
DFDVLSVFDGPPQPE

CSMD2

76

Q7Z408
KPLGPEVFQAYDPDS

CSPG4

571

Q6UVK1
PLPDNYPEGIDLVTD

ACE

631

P12821
LPTAPEAAENDYPGI

ALPK2

451

Q86TB3
DILAPPYDPDDGRDC

ADO

206

Q96SZ5
PDEPDILDDLYGPIA

FAM47DP

341

A6NHR8
YDSNTPGPAGDNPLE

GPNMB

346

Q14956
DSYLEPDSPEPGRLE

SH3BP2

181

P78314
PPPVDYEDEEAAVVQ

ABI1

416

Q8IZP0
ISFPGPAEEDLDPQY

DLGAP2

46

Q9P1A6
DEQEPPAYDQAPEVT

CABYR

266

O75952
GSQDYPDGQLPIPED

APBA2

156

Q99767
DVVAGNPYEPHPSEV

CAPN8

516

A6NHC0
EEKAPGPEDLSYSDP

DNHD1

2236

Q96M86
EAAGEGPALYEDPPD

APEX1

36

P27695
NEDPLVPDVSYGPSS

CDH13

446

P55290
IESPYGETISPEDAP

CSTF2

111

P33240
TEEGKENYLNPPEVP

DNAI3

121

Q8IWG1
ESGYDVLANPPGPED

BCOR

1611

Q6W2J9
FENPDPSDGFVLIPD

DCPS

191

Q96C86
TDDYRPGVDPALSDP

DAXX

341

Q9UER7
DYEPEGVPDNSPNLQ

TP53BP2

831

Q13625
QPEAPPNYADVVSEE

ARRDC4

346

Q8NCT1
VDAYPIKPEAPGEDA

PYY2

16

Q9NRI6
GETPGPEPLTLDSYQ

RELB

526

Q01201
DGETPDPEDPSRKIY

LTA4H

176

P09960
KSYGDEEEEPALSPP

LTN1

1421

O94822
GPDYEEGPNSLINEE

CERT1

306

Q9Y5P4
APNPITGEDEPYFPE

ANO7

476

Q6IWH7
EDGDNPYPSKEDTPT

ARHGAP10

621

A1A4S6
YGDPPEELPDFSEDP

CASK

321

O14936
DGTQQEYPPADPSEH

MGAT3

466

Q09327
EEGVVEYCTAEAPPP

NAIF1

181

Q69YI7
PEESQPPQLYAADEE

EXOSC6

11

Q5RKV6
PPQLYAADEEEAPGT

EXOSC6

16

Q5RKV6
QALEPPLDIAYGADG

SPATA18

431

Q8TC71
TEPLDEDSPGVYENG

JPH4

436

Q96JJ6
FEQAYPDPGPEAAQA

LOXL1

286

Q08397
AQPAPPELNSESEDY

DCLK1

711

O15075
EYVEPGEDFPASPQR

DYNC1LI1

196

Q9Y6G9
ADEDPGVPPYDSVQV

CDH24

751

Q86UP0
ALEQGSPPDISPYEV

PDX1

56

P52945
EIIPDRDGSDPYQEP

PCYT2

311

Q99447
DNAPEILYPALPTDG

PCDHGA10

561

Q9Y5H3
APADTYPATGPADDE

MUCL1

26

Q96DR8
YPATGPADDEAPDAE

MUCL1

31

Q96DR8
PDETEDPEPNYAGEP

NCF1

216

P14598
FPPPPDDDIYDGIEE

FYB1

616

O15117
GTTPDYQDPTPGEEE

COL11A2

286

P13942
PPVRQDPDSGPDYEA

SLC25A28

51

Q96A46
PQNAGDLPSPDGDYD

MYO10

1076

Q9HD67
PPYDDATVNGAAKEP

LAPTM4B

296

Q86VI4
DELDCYPTEEPAPQA

LRP6

1356

O75581
PEDGLSPSEPLNIYE

EXPH5

1946

Q8NEV8
EEGEYFNVPVPPEGS

PRKCB

281

P05771
PQPPPEEYAGADDVS

NAGS

56

Q8N159
GEAAAPESPHQAEPY

IRF7

256

Q92985
EPIPAGAPGANDTEY

EPHA10

476

Q5JZY3
VPVGYEPDPADLALS

HLF

171

Q16534
ETPDKAEPPFYVGSN

ADARB1

181

P78563
ATPGPPADELYAALE

TAMALIN

46

Q7Z6J2
EYGPSPGESELAVNP

DQX1

11

Q8TE96
PEIYQETPGPEDLST

HEMGN

396

Q9BXL5
SPDETEDPEPNYAGE

NCF1B

216

A6NI72
SPDETEDPEPNYAGE

NCF1C

191

A8MVU1
PLYLDDDGLPFPTDV

MTMR4

1006

Q9NYA4
TPDPEYPADASQNGI

ALPI

231

P09923
EEPPIESQDYTPGQE

PAGE3

41

Q5JUK9
TTVYAEDADPPGLPA

PCDH15

946

Q96QU1
AKPVQEEGDPYAELP

OTOS

21

Q8NHW6
SLPSSPEPEDGDKVY

CCSER2

701

Q9H7U1
EPGPEPDTVEAVIEY

KLHL11

146

Q9NVR0
NADDSYEPPPVEQET

BLNK

91

Q8WV28
NEDKSPYPNPETTGE

CACNA1C

831

Q13936
PAKPPEDEPDADGYE

DOC2B

106

Q14184
QYPELPPDFIFGEDA

BABAM2

76

Q9NXR7
SPDTNYEPPGEDKTQ

CENPF

1726

P49454
AEGPDPEYDESDVPA

EIF2AK1

31

Q9BQI3
FEPPGDIEFEDYTQP

FNBP1

276

Q96RU3
NDGKEPPPVVNYEED

FER

391

P16591
GDLDLGPVETEPPYA

EXTL3

571

O43909
TLADQSPGPGPVYAD

COL6A5

16

A8TX70
PYSEEDPDEGVAGAP

IL2RB

386

P14784
QEADNDPTAPPYDSI

CDH11

726

P55287
ARYTTPEDATPEPGE

GNAS

316

P63092
DPEAGGDAATPDYVL

CCDC57

566

Q2TAC2
YDPSAGDVPQTQPEE

ANK3

2176

Q12955
EGDYVPDSPALLPIE

CDK11A

391

Q9UQ88
TYGEGEENPDQPTDP

COL5A1

356

P20908
DLFQDDLYPDTPGPE

CORO6

356

Q6QEF8
VAPQPPGEDDAPYDV

EFS

176

O43281
AELNPFGDPDSEEPI

EHBP1

276

Q8NDI1
GAPQGAVYTDIPAPE

HOXC13

86

P31276
ESENEDDGYDVPKPP

CBL

766

P22681
LQENDVDPTAPPYDS

CDH12

721

P55289
DVNDNPPELATPYEA

CDH22

491

Q9UJ99
PPELATPYEAAVCED

CDH22

496

Q9UJ99
EADNDPTAPPYDSIQ

CDH8

731

P55286
KEADVDPGAPPYDSL

CDH7

716

Q9ULB5
PGPEDGQAPVLTYID

FAM135B

541

Q49AJ0
YDDIPVEATGSNCPP

DDX3Y

161

O15523
YAPEITAPEENEELP

SAMD15

656

Q9P1V8
DPYDPGEEDPAQSRA

NOC4L

416

Q9BVI4
KAADNDPTAPPYDSL

CDH2

841

P19022
PGPPEKTEDEVYQAQ

FUZ

346

Q9BT04
SLYHPPPEEDQGEER

PRAP1

111

Q96NZ9
SPEEELDGYEPEPLG

MCL1

121

Q07820
IPDTYAQTEGDAEPP

PRR15L

26

Q9BU68
YPGPDEKAPQEAAGD

INSM1

411

Q01101
QRQTPAGPETEEEPY

MTX1

401

Q13505
EPDPEPGSDILGYIN

FAM83G

416

A6ND36
PLAPAPAGEGDQEYV

GAREM2

396

Q75VX8
LMEPEGESYEDPPQE

SNCB

111

Q16143
GDLYPPVEEPVASTD

TAF7

101

Q15545
AGPAEEFPEPEENAA

SPEF2

1676

Q9C093
QPPPPEEEEEEANSY

RPH3A

371

Q9Y2J0
YEDAESRLEPDPAGP

SHD

46

Q96IW2
TPYEEQDPETADGPP

SHD

146

Q96IW2
DPDPNCVDRPVEGYL

LTF

441

P02788
EPDAADGPYDPNSVR

SMAD6

451

O43541
DGPEGQAYDVDFTPP

KARS1

376

Q15046
VATLPDDVQPGPDFY

MIA3

1161

Q5JRA6
GRYLCQPDSPEDAEP

NCKAP5

1736

O14513
DYTPQPPLSKEGESE

SLC24A2

96

Q9UI40
ENYFPELDRPDVPQG

PLEKHG4

756

Q58EX7
DDEAPSDGAQFPPIA

SKAP2

96

O75563
REIELYGCPPDFPDE

LARS1

106

Q9P2J5
REDQEGSPPETSLPY

MYBL2

276

P10244
YNVPEEPPLLGAEDS

FAM20A

101

Q96MK3
DTVSPAPEPQAAYED

PRDM16

1141

Q9HAZ2
NPDECQPYELPDGSV

NEU1

261

Q99519
DEEPVAAEPDYVQPQ

PHF12

191

Q96QT6
SAEQVDDPPEPVYAN

ARHGAP27

216

Q6ZUM4
PSYEEATRNPPGEEA

SMIM28

131

A0A1B0GU29
YEQIGPEADPNLAPA

SIK2

621

Q9H0K1
DLDPNPGDLYPESLE

SHROOM2

701

Q13796
KGVYQELPNSDPADP

SLFN11

171

Q7Z7L1
EPDLESQYPGSGSIP

SNCAIP

756

Q9Y6H5
YAVPPLPVSEGDAEQ

TANC2

61

Q9HCD6
PPPYELSESQASENG

TENM2

2506

Q9NT68
NNYPDSDDDTEAPPP

ARHGAP5

976

Q13017
QDRGPATAEVPYPDD

SKIV2L

886

Q15477
EGVPLPFYQPTEEDA

POLA2

321

Q14181
PLQLPPEDAYVGNAD

MLXIPL

266

Q9NP71
AGRPSEEPEPDYEAI

PAG1

376

Q9NWQ8
PALATPSPEEGEIQY

SIGLEC12

551

Q96PQ1
GEYLEQDEEQPTPSG

STRC

676

Q7RTU9
EADEVPAYCVPPQEG

SCARF1

531

Q14162
YVPPTQEDGVDPVEA

SSRP1

166

Q08945
KDDLAIPPPDYGAAS

BAIAP2

461

Q9UQB8
PDYLGPAPLEDIAEQ

CHAC2

116

Q8WUX2
VAESTPPGNDEPYTE

CLCA1

106

A8K7I4
TYEEAVSFPVAEGPP

TMEM61

131

Q8N0U2
SFYIDEASPVGPEQP

PLCXD3

41

Q63HM9
DIDGDEDLPGPPVRY

UBA6

1031

A0AVT1
SPVVPDYLPTENGDF

UHRF1BP1L

891

A0JNW5
DTDSDDYAPPQDGPA

TULP4

231

Q9NRJ4
SEDLVPPLEAGAAPY

TNFAIP2

6

Q03169
PPLEAGAAPYREEEE

TNFAIP2

11

Q03169
ESEAPYLLSPEAGPA

ZBTB5

441

O15062
PDGPEAPLDELVGAY

UNC93B1

26

Q9H1C4
EDEPSPEAQPIAAYK

nan

296

Q6ZSR9
YPNPDPLETQTGVLD

TRAPPC11

376

Q7Z392
DEPPEVYGDFEPLVA

TOR1AIP1

61

Q5JTV8
SGRSPFYEPDPQETE

SPEG

3156

Q15772
EEEEDEGPAPPSLYP

PLPPR3

456

Q6T4P5
PPPGYISEDGETSDQ

SMAD2

221

Q15796
PGTYQELAEAPGDPQ

TBC1D10C

116

Q8IV04
GNEPYSGEARSIPEP

ARHGAP23

171

Q9P227
TYDNVPSLPGSPGEE

ARHGAP25

501

P42331
PAPAGGDDDYIEQTL

YY1

136

P25490
PYSIDSEPGSPLLDD

SREBF2

446

Q12772
AEAYPSKPDNPGEDA

NPY

26

P01303
APPDDDDRLENVQYP

ZBTB44

361

Q8NCP5
AFLGPENPEEPYLDG

SMC1A

1096

Q14683
YAPTIAPSPEDGFEV

SLC6A9

666

P48067
GQGEAPPQYLTDDLE

TACC2

291

O95359
NPAPGQDYLLPEAEE

USP9Y

2026

O00507
GTDTDIDGYPDQALP

THBS3

456

P49746
YSEPEGSAGPSPEVE

SNX19

316

Q92543
YQEEGVPVQFDLPDP

MYO18B

991

Q8IUG5
GAEYAPLEEGPEEPL

SLC30A3

211

Q99726
DPPPEYEDIVNSNSA

PRRG1

191

O14668
EEYPALPQGAEASLP

VXN

156

Q8TAG6
LGPPPDNDDVVNDFD

UBLCP1

86

Q8WVY7
GEYLEQDEEQPTPSG

STRCP1

676

A6NGW2
KADLIPYQDSPEGPD

GTF3C2

756

Q8WUA4
GEPDYPSAEDNQNLP

TMC5

221

Q6UXY8
ETLPESEKYNPGPQD

ERCC4

836

Q92889
EGTQYPPPAAAEQEV

ZNF777

101

Q9ULD5
PGTPYSEEPAGEAAQ

ZNF335

896

Q9H4Z2
VPDGPDPQNSTYGVE

PTPRH

141

Q9HD43
SSPPQIKDEPEDDGY

TOP1

111

P11387
PPKYEEIVAANPGAD

PRRG3

216

Q9BZD7
EPKSQASGPEPELYA

SIT1

156

Q9Y3P8
QDAPFGPEDYDQLAP

PPIP5K1

641

Q6PFW1
ALFPGDGPYLEDPED

ZBTB46

526

Q86UZ6
DGPYLEDPEDPRGEA

ZBTB46

531

Q86UZ6
NIDPESDPYVTPGSV

TNRC6B

1491

Q9UPQ9
PYPDQIICPDEEGTE

VMP1

161

Q96GC9
SDHYPAADPDGPVFE

VPS13D

596

Q5THJ4
VYGAQPSQPEAFEDP

ZBTB3

386

Q9H5J0
EPGDTPTDEPDALYV

KMT2D

376

O14686
TISLSDGEEPPPYQG

LDLRAD4

171

O15165
PGNAEEQPSLYEKAP

TMEM35A

146

Q53FP2
LPENVDFPDPYQDPS

GRIN2A

1141

Q12879