Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	insulin receptor activity	INSR INSRR	1.11e-04	3	122	2	GO:0005009
GeneOntologyMolecularFunction	structural constituent of synapse	MAGI2 NEFL CTNND2 BSN	1.24e-04	42	122	4	GO:0098918
GeneOntologyCellularComponent	vesicle membrane	EPN3 SLC29A3 ABCA12 INSR KIF16B SLC5A7 FNDC3A APOB TLR8 C2CD5 CLCN3 NSG2 CUZD1 MTMR2 DMBT1 BSN VPS13B IL7R CXCR2 EPHB1	1.02e-04	1325	124	20	GO:0012506
GeneOntologyCellularComponent	somatodendritic compartment	GABRB1 PDE2A ANK3 LZTS3 INSR NAIP SLC5A7 APOB GRM2 PTGER3 RGS7 MAGI2 NSG2 UNC5C TPX2 MTMR2 CTNND2 BSN EPHB1	1.12e-04	1228	124	19	GO:0036477
GeneOntologyCellularComponent	dendrite	GABRB1 PDE2A ANK3 LZTS3 INSR SLC5A7 GRM2 RGS7 MAGI2 NSG2 UNC5C MTMR2 CTNND2 BSN EPHB1	1.73e-04	858	124	15	GO:0030425
GeneOntologyCellularComponent	dendritic tree	GABRB1 PDE2A ANK3 LZTS3 INSR SLC5A7 GRM2 RGS7 MAGI2 NSG2 UNC5C MTMR2 CTNND2 BSN EPHB1	1.77e-04	860	124	15	GO:0097447
GeneOntologyCellularComponent	synaptic membrane	GABRB1 PDE2A ANK3 SLC5A7 GRM2 RGS7 PCDH17 MAGI2 CLCN3 NSG2 MTMR2 BSN	1.84e-04	583	124	12	GO:0097060
GeneOntologyCellularComponent	insulin receptor complex	INSR INSRR	2.08e-04	4	124	2	GO:0005899
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	EPN3 SLC29A3 ABCA12 INSR KIF16B SLC5A7 APOB TLR8 C2CD5 CLCN3 NSG2 CUZD1 MTMR2 DMBT1 BSN VPS13B IL7R CXCR2 EPHB1	2.50e-04	1307	124	19	GO:0030659
GeneOntologyCellularComponent	early endosome membrane	KIF16B SLC5A7 CLCN3 NSG2 MTMR2 VPS13B EPHB1	2.76e-04	212	124	7	GO:0031901
GeneOntologyCellularComponent	axon	PDE2A ANK3 INSR INSRR SLC5A7 CLASP2 GRM2 NEFL CLCN3 UNC5C TPX2 MTMR2 BSN EPHB1	8.28e-04	891	124	14	GO:0030424
GeneOntologyCellularComponent	endosome membrane	SLC29A3 INSR KIF16B SLC5A7 APOB TLR8 CLCN3 NSG2 MTMR2 VPS13B EPHB1	9.24e-04	602	124	11	GO:0010008
GeneOntologyCellularComponent	postsynapse	GABRB1 ANK3 LZTS3 PRICKLE1 GRM2 RGS7 PCDH17 MAGI2 NEFL SENP1 CLCN3 NSG2 MTMR2 CTNND2 BSN	1.03e-03	1018	124	15	GO:0098794
GeneOntologyCellularComponent	mitotic spindle	CLASP2 TPX2 PKHD1 EML1 HSF1 CXCR2	1.28e-03	201	124	6	GO:0072686
MousePheno	abnormal nervous system tract morphology	VAX1 PRICKLE1 MARCHF7 TERT NFIA UNC5C EML1 HSF1 KDM4B EPHB1	1.40e-06	189	104	10	MP:0000778
MousePheno	abnormal brain commissure morphology	VAX1 MARCHF7 TERT NFIA EML1 HSF1 KDM4B EPHB1	2.63e-05	161	104	8	MP:0002199
MousePheno	abnormal kidney collecting duct morphology	FAT4 ANK3 PRICKLE1 PKHD1 AKAP11	4.47e-05	53	104	5	MP:0004754
MousePheno	abnormal corpus callosum morphology	VAX1 MARCHF7 TERT NFIA EML1 HSF1 KDM4B	4.89e-05	129	104	7	MP:0000780
MousePheno	abnormal dorsal telencephalic commissure morphology	VAX1 MARCHF7 TERT NFIA EML1 HSF1 KDM4B	5.67e-05	132	104	7	MP:0008219
MousePheno	absent corpus callosum	VAX1 NFIA EML1 KDM4B	1.00e-04	33	104	4	MP:0002196
MousePheno	abnormal mitotic spindle morphology	PRICKLE1 TPX2 PKHD1 EML1	1.42e-04	36	104	4	MP:0009760
MousePheno	abnormal brain white matter morphology	VAX1 MARCHF7 TERT NFIA EML1 HSF1 KDM4B EPHB1	1.49e-04	206	104	8	MP:0008026
MousePheno	fused incisors	VAX1 PRICKLE1	1.64e-04	3	104	2	MP:0030474
Domain	fn3	COL12A1 INSR INSRR OBSCN FNDC3A ROS1 SDK1 IL7R EPHB1	1.10e-06	162	121	9	PF00041
Domain	FN3	COL12A1 INSR INSRR OBSCN FNDC3A ROS1 SDK1 IL7R EPHB1	5.97e-06	199	121	9	PS50853
Domain	FN3_dom	COL12A1 INSR INSRR OBSCN FNDC3A ROS1 SDK1 IL7R EPHB1	8.87e-06	209	121	9	IPR003961
Domain	FN3	COL12A1 INSR INSRR OBSCN FNDC3A ROS1 SDK1 EPHB1	2.76e-05	185	121	8	SM00060
Domain	N-SET	SETD1A SETD1B	4.16e-05	2	121	2	PF11764
Domain	N-SET	SETD1A SETD1B	4.16e-05	2	121	2	SM01291
Domain	COMPASS_Set1_N-SET	SETD1A SETD1B	4.16e-05	2	121	2	IPR024657
Domain	Tyr_kinase_rcpt_2_CS	INSR INSRR ROS1	4.21e-05	11	121	3	IPR002011
Domain	RECEPTOR_TYR_KIN_II	INSR INSRR ROS1	5.59e-05	12	121	3	PS00239
Domain	Tyr_kinase_insulin-like_rcpt	INSR INSRR	1.24e-04	3	121	2	IPR016246
Domain	-	COL12A1 TRIM2 INSR INSRR OBSCN FNDC3A MFAP3 UNC5C PKHD1 ROS1 SDK1 IL7R EPHB1	3.68e-04	663	121	13	2.60.40.10
Domain	PROTEIN_KINASE_TYR	INSR INSRR OBSCN ROS1 EPHB1	4.21e-04	97	121	5	PS00109
Domain	Tyr_kinase_AS	INSR INSRR OBSCN ROS1 EPHB1	4.21e-04	97	121	5	IPR008266
Domain	Ig-like_fold	COL12A1 TRIM2 INSR INSRR OBSCN FNDC3A MFAP3 UNC5C PKHD1 ROS1 SDK1 IL7R EPHB1	6.64e-04	706	121	13	IPR013783
Domain	Recep_L_domain	INSR INSRR	8.56e-04	7	121	2	PF01030
Domain	Furin-like	INSR INSRR	8.56e-04	7	121	2	PF00757
Domain	Rcpt_L-dom	INSR INSRR	8.56e-04	7	121	2	IPR000494
Domain	Furin-like_Cys-rich_dom	INSR INSRR	8.56e-04	7	121	2	IPR006211
Domain	Plakophilin/d_Catenin	PKP3 CTNND2	8.56e-04	7	121	2	IPR028435
Domain	-	INSR INSRR	8.56e-04	7	121	2	3.80.20.20
Domain	-	CPA5 CPB2	1.14e-03	8	121	2	3.30.70.340
Domain	Propep_M14	CPA5 CPB2	1.14e-03	8	121	2	PF02244
Domain	M14A_act_pep	CPA5 CPB2	1.14e-03	8	121	2	IPR003146
Domain	ZU5	ANK3 UNC5C	1.45e-03	9	121	2	SM00218
Domain	ZU5	ANK3 UNC5C	1.81e-03	10	121	2	PS51145
Domain	ARM_REPEAT	ARMCX2 PKP3 CTNND2	2.20e-03	40	121	3	PS50176
Domain	ARM	ARMCX2 PKP3 CTNND2	2.20e-03	40	121	3	SM00185
Domain	Tyr_kinase_cat_dom	INSR INSRR ROS1 EPHB1	2.57e-03	88	121	4	IPR020635
Domain	TyrKc	INSR INSRR ROS1 EPHB1	2.57e-03	88	121	4	SM00219
Domain	OA_transporter	SLCO1B1 SLCO1C1	2.63e-03	12	121	2	IPR004156
Domain	ZU5	ANK3 UNC5C	2.63e-03	12	121	2	PF00791
Domain	ZU5_dom	ANK3 UNC5C	2.63e-03	12	121	2	IPR000906
Domain	OATP	SLCO1B1 SLCO1C1	2.63e-03	12	121	2	PF03137
Domain	Armadillo	ARMCX2 PKP3 CTNND2	3.49e-03	47	121	3	IPR000225
Domain	ZP_2	CUZD1 DMBT1	3.60e-03	14	121	2	PS51034
Domain	ZP_1	CUZD1 DMBT1	3.60e-03	14	121	2	PS00682
Domain	WW	CEP164 MAGI2 WWC1	3.71e-03	48	121	3	SM00456
Domain	CUB	DCBLD1 CUZD1 DMBT1	3.93e-03	49	121	3	PF00431
Domain	ZP	CUZD1 DMBT1	4.14e-03	15	121	2	SM00241
Domain	CUB	DCBLD1 CUZD1 DMBT1	4.16e-03	50	121	3	SM00042
Domain	WW_DOMAIN_1	CEP164 MAGI2 WWC1	4.40e-03	51	121	3	PS01159
Domain	WW_DOMAIN_2	CEP164 MAGI2 WWC1	4.40e-03	51	121	3	PS50020
Domain	WW_dom	CEP164 MAGI2 WWC1	4.65e-03	52	121	3	IPR001202
Domain	-	DCBLD1 CUZD1 DMBT1	4.65e-03	52	121	3	2.60.120.290
Domain	GRAM	TBC1D9 MTMR2	4.71e-03	16	121	2	SM00568
Domain	Post-SET_dom	SETD1A SETD1B	4.71e-03	16	121	2	IPR003616
Domain	PostSET	SETD1A SETD1B	4.71e-03	16	121	2	SM00508
Domain	POST_SET	SETD1A SETD1B	4.71e-03	16	121	2	PS50868
Domain	CUB	DCBLD1 CUZD1 DMBT1	4.91e-03	53	121	3	PS01180
Domain	Znf_C3HC4_RING-type	TRIM2 MARCHF7 MEX3C ZNRF3 RNF145	5.26e-03	172	121	5	IPR018957
Domain	Znf_RING-CH	MARCHF7 RNF145	5.31e-03	17	121	2	IPR011016
Domain	RINGv	MARCHF7 RNF145	5.31e-03	17	121	2	SM00744
Domain	Propept_inh	CPA5 CPB2	5.31e-03	17	121	2	IPR009020
Domain	ZP_dom	CUZD1 DMBT1	5.31e-03	17	121	2	IPR001507
Domain	Zona_pellucida	CUZD1 DMBT1	5.31e-03	17	121	2	PF00100
Domain	Cadherin_CS	FAT4 PCDHGA2 PCDHA1 PCDH17	5.53e-03	109	121	4	IPR020894
Domain	Zn_pept	CPA5 CPB2	5.95e-03	18	121	2	SM00631
Domain	Furin_repeat	INSR INSRR	5.95e-03	18	121	2	IPR006212
Domain	FU	INSR INSRR	5.95e-03	18	121	2	SM00261
Domain	CUB_dom	DCBLD1 CUZD1 DMBT1	6.02e-03	57	121	3	IPR000859
Domain	CADHERIN_1	FAT4 PCDHGA2 PCDHA1 PCDH17	6.27e-03	113	121	4	PS00232
Domain	Cadherin	FAT4 PCDHGA2 PCDHA1 PCDH17	6.27e-03	113	121	4	PF00028
Domain	CADHERIN_2	FAT4 PCDHGA2 PCDHA1 PCDH17	6.47e-03	114	121	4	PS50268
Domain	-	FAT4 PCDHGA2 PCDHA1 PCDH17	6.47e-03	114	121	4	2.60.40.60
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	EPN3 DCBLD1 RAD54L2 SENP1 NFIA PKP3 RBM14 EMD	3.29e-07	180	126	8	35198878
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	C15orf62 SETD1A ANK3 HJURP GLIS3 RAD54L2 TASOR2 TNRC18 TPX2 BSN GAB1	5.17e-07	430	126	11	35044719
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	FAT4 ANK3 INSR CLASP2 APOB TASOR2 ARID3B UBR5 UNC5C RBM14 EMD DEPDC7 SDK1 GAB1	9.42e-07	777	126	14	35844135
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	PDE2A ANK3 LZTS3 PAK5 CLASP2 GRM2 MAGI2 NEFL SENP1 UBR5 FAM120C EML1 CTNND2 BSN LRRFIP2	2.28e-06	963	126	15	28671696
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	TRIM2 LZTS3 ARMCX2 C2CD5 JMJD6 VPS13B	2.41e-06	105	126	6	9628581
Pubmed	Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.	DCBLD1 TERT ROS1	2.57e-06	8	126	3	23143601
Pubmed	Preserved pancreatic beta-cell development and function in mice lacking the insulin receptor-related receptor.	INSR INSRR	1.30e-05	2	126	2	11463843
Pubmed	TAFI deficiency causes maladaptive vascular remodeling after hemophilic joint bleeding.	CPB2 F8	1.30e-05	2	126	2	31465300
Pubmed	Regulation of the apolipoprotein B in heterozygous hypobetalipoproteinemic knock-out mice expressing truncated apoB, B81. Low production and enhanced clearance of apoB cause low levels of apoB.	APOB EPHB1	1.30e-05	2	126	2	10705993
Pubmed	SNP rs9387478 at ROS1-DCBLD1 Locus is Significantly Associated with Lung Cancer Risk and Poor Survival in Indian Population.	DCBLD1 ROS1	1.30e-05	2	126	2	36308382
Pubmed	Interaction of S-SCAM with neural plakophilin-related Armadillo-repeat protein/delta-catenin.	MAGI2 CTNND2	1.30e-05	2	126	2	10080919
Pubmed	Nucleolar localisation of three Hox homeoproteins.	HOXB7 HOXC6	1.30e-05	2	126	2	7738096
Pubmed	Expression and function of CXCR2, CXCR7 of acute leukemic cells in rat.	ACKR3 CXCR2	1.30e-05	2	126	2	25063073
Pubmed	Myotubularin-related 2 protein phosphatase and neurofilament light chain protein, both mutated in CMT neuropathies, interact in peripheral nerve.	NEFL MTMR2	1.30e-05	2	126	2	12837694
Pubmed	Characterization of a hybrid receptor formed by dimerization of the insulin receptor-related receptor (IRR) with the insulin receptor (IR): coexpression of cDNAs encoding human IRR and human IR in NIH-3T3 cells.	INSR INSRR	1.30e-05	2	126	2	8916919
Pubmed	Defective TAFI activation in hemophilia A mice is a major contributor to joint bleeding.	CPB2 F8	1.30e-05	2	126	2	30026184
Pubmed	The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation.	SETD1A SETD1B	1.30e-05	2	126	2	24550110
Pubmed	In Vivo and In Vitro Characterization of the RNA Binding Capacity of SETD1A (KMT2F).	SETD1A SETD1B	1.30e-05	2	126	2	38003223
Pubmed	O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry.	NEFL CTNND2 BSN	1.64e-05	14	126	3	16452088
Pubmed	Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	CDK12 TBC1D9 UBR5 WWC1 KDM4B	3.29e-05	100	126	5	10048485
Pubmed	Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.	APOB DOCK6 ABCG8	3.64e-05	18	126	3	23726366
Pubmed	Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development.	HOXB7 HOXC6	3.90e-05	3	126	2	2885844
Pubmed	Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox.	JMJD6 KDM4B	3.90e-05	3	126	2	28684529
Pubmed	Analyzing Somatic Genome Rearrangements in Human Cancers by Using Whole-Exome Sequencing.	TERT ROS1	3.90e-05	3	126	2	27153396
Pubmed	Identification of major tyrosine phosphorylation sites in the human insulin receptor substrate Gab-1 by insulin receptor kinase in vitro.	INSR GAB1	3.90e-05	3	126	2	10978177
Pubmed	WDR82, a key epigenetics-related factor, plays a crucial role in normal early embryonic development in mice.	SETD1A SETD1B	3.90e-05	3	126	2	21123813
Pubmed	Insulin receptor-related receptor as an extracellular alkali sensor.	INSR INSRR	3.90e-05	3	126	2	21641549
Pubmed	Co-segregation of thrombophilic disorders in factor V Leiden carriers; the contributions of factor VIII, factor XI, thrombin activatable fibrinolysis inhibitor and lipoprotein(a) to the absolute risk of venous thromboembolism.	CPB2 F8	3.90e-05	3	126	2	12368162
Pubmed	Molecular insight into the SETD1A/B N-terminal region and its interaction with WDR82.	SETD1A SETD1B	3.90e-05	3	126	2	37030068
Pubmed	Insulin receptor-related (Irr) is expressed in pre-implantation embryos: a possible relationship to "growth factor Y" and sex determination.	INSR INSRR	3.90e-05	3	126	2	21681845
Pubmed	TLR7/8 stress response drives histiocytosis in SLC29A3 disorders.	SLC29A3 TLR8	3.90e-05	3	126	2	37462944
Pubmed	The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers.	SETD1A SETD1B	3.90e-05	3	126	2	33567280
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	CDK12 SUN1 GLIS3 FNDC3A SENP1 PKP3 TPX2 RBM14 EMD	4.58e-05	457	126	9	32344865
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EPN3 SETD1A PDE2A MRPL21 SETD1B CDK12 OBSCN CLASP2 SLC35E2B TBC1D9 JUNB TNRC18 ZNRF3 DOCK6	4.98e-05	1105	126	14	35748872
Pubmed	Neither replication nor simulation supports a role for the axon guidance pathway in the genetics of Parkinson's disease.	PAK5 UNC5C EPHB1	6.80e-05	22	126	3	18628988
Pubmed	Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.	PRICKLE1 PCDHA1 PCDH17 NSG2 TBX5 EPHB1	7.66e-05	193	126	6	22589738
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	ANK3 LZTS3 GRM2 NEFL UBR5 AKAP11 CTNND2	7.76e-05	281	126	7	28706196
Pubmed	Impact of Oatp1c1 deficiency on thyroid hormone metabolism and action in the mouse brain.	SLCO1B1 SLCO1C1	7.78e-05	4	126	2	22294745
Pubmed	Lens epithelium-derived growth factor deSumoylation by Sumo-specific protease-1 regulates its transcriptional activation of small heat shock protein and the cellular response.	SENP1 HSF1	7.78e-05	4	126	2	22748127
Pubmed	CXCR2 Inhibition in Human Pluripotent Stem Cells Induces Predominant Differentiation to Mesoderm and Endoderm Through Repression of mTOR, β-Catenin, and hTERT Activities.	TERT CXCR2	7.78e-05	4	126	2	27188501
Pubmed	Macrophage-mediated enterocyte damage in BALB/c mice infected with different strains of Giardia lamblia.	HOXB7 HOXC6	7.78e-05	4	126	2	8235442
Pubmed	Contribution of SUN1 mutations to the pathomechanism in muscular dystrophies.	SUN1 EMD	7.78e-05	4	126	2	24375709
Pubmed	Prediction and diagnosis of bladder cancer recurrence based on urinary content of hTERT, SENP1, PPP1CA, and MCM5 transcripts.	TERT SENP1	7.78e-05	4	126	2	21106093
Pubmed	Expression of multiple homeobox genes within diverse mammalian haemopoietic lineages.	HOXB7 HOXC6	7.78e-05	4	126	2	2901346
Pubmed	Determination of Gab1 (Grb2-associated binder-1) interaction with insulin receptor-signaling molecules.	INSR GAB1	7.78e-05	4	126	2	9658397
Pubmed	DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169.	LZTS3 RAD54L2 AKAP11 DOCK6 LRRFIP2	8.51e-05	122	126	5	30773093
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	FAT4 FNDC3A APOB UBR5 TPX2 ROS1 EML1 DMBT1 HSF1 WWC1 LRRFIP2	9.83e-05	754	126	11	35906200
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ANK3 INSR NAIP OBSCN WDR27 CLASP2 TASOR2 SENP1 TNRC18 NFIA FAM120C ACKR3 PKP3 DOCK6 VPS13B KDM4B	9.92e-05	1489	126	16	28611215
Pubmed	Ca2+ homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling.	NFIA UNC5C EPHB1	1.14e-04	26	126	3	35927240
Pubmed	Unique phosphorylation mechanism of Gab1 using PI 3-kinase as an adaptor protein.	GABRB1 GAB1	1.29e-04	5	126	2	11606067
Pubmed	Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes.	SUN1 EMD	1.29e-04	5	126	2	19933576
Pubmed	The phosphotyrosine interactome of the insulin receptor family and its substrates IRS-1 and IRS-2.	INSR INSRR	1.29e-04	5	126	2	19001411
Pubmed	Loci from a genome-wide analysis of bilirubin levels are associated with gallstone risk and composition.	SLCO1B1 ABCG8	1.29e-04	5	126	2	20837016
Pubmed	Cloning and chromosomal mapping of an orphan chemokine receptor: mouse RDC1.	ACKR3 CXCR2	1.29e-04	5	126	2	9510554
Pubmed	Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration.	TRIM2 NEFL	1.29e-04	5	126	2	18687884
Pubmed	Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.	SETD1A SETD1B	1.29e-04	5	126	2	25561738
Pubmed	HIV-1 Vpr protein inhibits telomerase activity via the EDD-DDB1-VPRBP E3 ligase complex.	TERT UBR5	1.29e-04	5	126	2	23612978
Pubmed	Prickle1 promotes focal adhesion disassembly in cooperation with the CLASP-LL5β complex in migrating cells.	PRICKLE1 CLASP2	1.29e-04	5	126	2	27378169
Pubmed	Genetic risk for restenosis after coronary stenting.	INSR ROS1	1.29e-04	5	126	2	17275003
Pubmed	Chemokine receptors CXCR2 and CX3CR1 differentially regulate functional responses of bone-marrow endothelial progenitors during atherosclerotic plaque regression.	APOB CXCR2	1.29e-04	5	126	2	25765938
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SETD1A CDK12 SUN1 KIF16B FNDC3A AKAP11 BSN DOCK6 KDM4B	1.39e-04	529	126	9	14621295
Pubmed	The DNA sequence and comparative analysis of human chromosome 5.	NAIP CCNO PCDHA1 CTNND2	1.64e-04	75	126	4	15372022
Pubmed	Multiple roles of mesenchymal beta-catenin during murine limb patterning.	COL12A1 HOXC6 TBX5	1.75e-04	30	126	3	16495310
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CDK12 FNDC3A ZNRF3 UBR5 AKAP11 KDM4B	1.77e-04	225	126	6	12168954
Pubmed	Isolation of LERK-5: a ligand of the eph-related receptor tyrosine kinases.	INSR EPHB1	1.93e-04	6	126	2	8559144
Pubmed	Pax6 is required for establishing naso-temporal and dorsal characteristics of the optic vesicle.	VAX1 TBX5	1.93e-04	6	126	2	12223410
Pubmed	Dyrk2-associated EDD-DDB1-VprBP E3 ligase inhibits telomerase by TERT degradation.	TERT UBR5	1.93e-04	6	126	2	23362280
Pubmed	Samp1 is functionally associated with the LINC complex and A-type lamina networks.	SUN1 EMD	1.93e-04	6	126	2	21610090
Pubmed	Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome.	MARCHF7 UBR5	1.93e-04	6	126	2	25594175
Pubmed	Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects.	GLIS3 SLCO1B1	1.93e-04	6	126	2	19901119
Pubmed	Eomesodermin, a target gene of Pou4f2, is required for retinal ganglion cell and optic nerve development in the mouse.	NEFL TBX5	1.93e-04	6	126	2	18077589
Pubmed	Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.	MAGI2 NEFL	1.93e-04	6	126	2	15122254
Pubmed	A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.	INSR GLIS3 NFIA	1.94e-04	31	126	3	23408906
Pubmed	Association of a polymorphism of the apolipoprotein E gene with chronic kidney disease in Japanese individuals with metabolic syndrome.	CPB2 APOB ROS1 ABCG8	2.00e-04	79	126	4	19056482
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	PAK5 CLASP2 NEFL RBM14 CTNND2 BSN	2.04e-04	231	126	6	16452087
Pubmed	The protein tyrosine kinase family of the human genome.	INSR INSRR ROS1 EPHB1	2.42e-04	83	126	4	11114734
Pubmed	A combination of activation and repression by a colinear Hox code controls forelimb-restricted expression of Tbx5 and reveals Hox protein specificity.	HOXC6 TBX5	2.70e-04	7	126	2	24651482
Pubmed	Developmental origins of precocial forelimbs in marsupial neonates.	HOXC6 TBX5	2.70e-04	7	126	2	21098569
Pubmed	CXXC finger protein 1 contains redundant functional domains that support embryonic stem cell cytosine methylation, histone methylation, and differentiation.	SETD1A SETD1B	2.70e-04	7	126	2	19433449
Pubmed	Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.	ANK3 OBSCN	3.59e-04	8	126	2	28826662
Pubmed	CFP1 interacts with DNMT1 independently of association with the Setd1 Histone H3K4 methyltransferase complexes.	SETD1A SETD1B	3.59e-04	8	126	2	18680430
Pubmed	Single-Cell Transcriptomics Reveals Chemotaxis-Mediated Intraorgan Crosstalk During Cardiogenesis.	CXCR2 TBX5	3.59e-04	8	126	2	31221018
Pubmed	The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.	SETD1A SETD1B	3.59e-04	8	126	2	22266653
Pubmed	GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain.	GRM2 CXCR2	3.59e-04	8	126	2	9651375
Pubmed	Comparative analysis of the signaling capabilities of the insulin receptor-related receptor.	INSR INSRR	3.59e-04	8	126	2	15629149
Pubmed	Vax2 inactivation in mouse determines alteration of the eye dorsal-ventral axis, misrouting of the optic fibres and eye coloboma.	VAX1 TBX5	3.59e-04	8	126	2	11830579
Pubmed	Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept.	GABRB1 BSN	3.59e-04	8	126	2	19567891
Pubmed	Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters.	SLCO1B1 SLCO1C1	3.59e-04	8	126	2	19129463
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	SETD1A SETD1B	3.59e-04	8	126	2	23130995
Pubmed	Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex.	SETD1A SETD1B	3.59e-04	8	126	2	17355966
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FAT4 OBSCN SLC5A7 PCDH17 FAM120C ZFR2 PKHD1 EMD LRRFIP2 CXCR2	3.61e-04	736	126	10	29676528
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	RAD54L2 ARMCX2 SENP1 UBR5 PKP3 MTMR2	4.00e-04	262	126	6	36880596
Pubmed	Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.	INSR INSRR EPHB1	4.16e-04	40	126	3	30898150
Pubmed	Cdx and T Brachyury Co-activate Growth Signaling in the Embryonic Axial Progenitor Niche.	PRICKLE1 HOXB7 HOXC6	4.16e-04	40	126	3	28009287
Pubmed	Acquisition of neural fate by combination of BMP blockade and chromatin modification.	NFIA TBX5	4.61e-04	9	126	2	37771660
Pubmed	Identification of genetic variants associated with response to statin therapy.	APOB SLCO1B1	4.61e-04	9	126	2	19667110
Pubmed	Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.	SETD1A SETD1B	4.61e-04	9	126	2	22665483
Pubmed	Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis.	SLCO1C1 QPCT	4.61e-04	9	126	2	22569225
Pubmed	Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells.	SETD1A TERT	4.61e-04	9	126	2	22723415
Pubmed	Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes.	PRICKLE1 MAGI2	4.61e-04	9	126	2	20534871
GeneFamily	Fibronectin type III domain containing	COL12A1 INSR INSRR OBSCN FNDC3A ROS1 SDK1 IL7R EPHB1	1.35e-07	160	93	9	555
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	INSR INSRR ROS1	1.13e-03	40	93	3	321
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	ARMCX2 PKP3 CTNND2	1.40e-03	43	93	3	409
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000	GABRB1 FAT4 TRIM2 CDK12 INSR SLC5A7 GLIS3 GAL3ST4 CPB2 CLASP2 PTGER3 PCDH17 MAGI2 NFIA ACKR3 RBM14 CTNND2 RNF145 TBX5	7.18e-08	769	121	19	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000	GABRB1 FAT4 SETD1B ANK3 INSR SLC5A7 CLASP2 PCDH17 TASOR2 NEFL MFAP3 NFIA CTNND2 PDE7B VPS13B TBX5	1.39e-05	806	121	16	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000	GABRB1 FAT4 ANK3 CDK12 INSR SLC5A7 CLASP2 PTGER3 PCDH17 NEFL NFIA ACKR3 PDE7B VPS13B TBX5 EPHB1	1.66e-05	818	121	16	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlas	ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000	DOK6 FAT4 COL12A1 SLC5A7 GLIS3 CCNO APOB PCDH17 HOXB7 TNRC18 HOXC6 NSG2 ACKR3 UNC5C PDE7B IL7R TBX5	4.87e-05	994	121	17	PCBC_ratio_EB_vs_SC_1000
CoexpressionAtlas	cerebral cortex	GABRB1 DOK6 VAX1 PDE2A TRIM2 GPR19 LZTS3 PAK5 CLASP2 PCDHA1 GRM2 RGS7 PCDH17 MAGI2 NEFL SLCO1C1 ZFR2 CACNA1I CTNND2 BSN EPHB1	5.36e-05	1428	121	21	cerebral cortex
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000	GABRB1 FAT4 TRIM2 INSR SLC5A7 GAL3ST4 CLASP2 PTGER3 PCDH17 TBC1D9 NEFL CLCN3 NSG2 NFIA CTNND2	6.49e-05	818	121	15	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
CoexpressionAtlas	ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_500	COL12A1 SLC5A7 GLIS3 CCNO APOB HOXB7 HOXC6 NSG2 ACKR3 UNC5C TBX5	1.33e-04	498	121	11	PCBC_ratio_EB_vs_SC_500
CoexpressionAtlas	DevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#1_top-relative-expression-ranked_1000	TRIM2 GAL3ST4 FIGN NEFL HOXC6	1.57e-04	89	121	5	gudmap_developingGonad_e11.5_testes_k1_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500_k-means-cluster#4	VAX1 GAL3ST4 NSG2 ACKR3 EPHB1	1.65e-04	90	121	5	Facebase_RNAseq_e8.5_Floor Plate_500_K4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#1_top-relative-expression-ranked_1000	CDK12 INSR SLC5A7 CLASP2 PTGER3 NFIA RNF145	1.98e-04	209	121	7	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k1
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_500	GABRB1 FAT4 COL12A1 DCBLD1 MAGI2	2.03e-04	94	121	5	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000	GPLD1 FAT4 SETD1B ANK3 CDK12 INSR CLASP2 PCDH17 NEFL CLCN3 NFIA RBM14 CTNND2 TBX5	2.03e-04	806	121	14	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#1_top-relative-expression-ranked_1000	ANK3 HJURP GAL3ST4 FIGN DDIAS TPX2 RBM14	2.04e-04	210	121	7	gudmap_developingKidney_e15.5_Peripheral blastema_1000_k1
CoexpressionAtlas	dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_200	GABRB1 COL12A1 MAGI2 NFIA	2.20e-04	52	121	4	gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k1_200
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 COL12A1 ABCA12 OBSCN APOB FIGN PKHD1 ROS1 SDK1	2.87e-09	184	126	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 COL12A1 ABCA12 OBSCN APOB FIGN PKHD1 ROS1 SDK1	2.87e-09	184	126	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 COL12A1 ABCA12 OBSCN APOB FIGN PKHD1 ROS1 SDK1	2.87e-09	184	126	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CCNO FNDC3A FIGN MAGI2 ZNRF3 CACNA1I EML1 SDK1 EPHB1	3.31e-09	187	126	9	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	TRIM2 ANK3 GLIS3 NFIA ROS1 RNF145 SDK1 WWC1	5.83e-08	185	126	8	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOK6 PRICKLE1 INSR GLIS3 FIGN PKHD1 SDK1 WWC1	7.16e-08	190	126	8	989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM2 ANK3 GLIS3 PTGER3 ZNRF3 PKHD1 SDK1 WWC1	8.75e-08	195	126	8	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOK6 OBSCN FIGN SLCO1C1 UNC5C DOCK6 TBX5	7.66e-07	178	126	7	185b44700f06ec58b3c09c80520502166c965fd6
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GLIS3 MAGI2 ZNRF3 PKHD1 PDE7B SDK1 WWC1	7.66e-07	178	126	7	544379f5a6145429762258d426b876bb36c112f5
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAK5 SLC5A7 RGS7 NEFL NSG2 ZFR2 EPHB1	7.95e-07	179	126	7	228d12ed1c8dc92aefbcea4aaf7d108783c22be0
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	ANK3 GLIS3 RGS7 ZNRF3 ROS1 DMBT1 WWC1	1.10e-06	188	126	7	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOK6 OBSCN FIGN SLCO1C1 UNC5C DOCK6 TBX5	1.10e-06	188	126	7	ee151792c7ac9afe820f1a281c6dab383799f358
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	DOK6 INSR FIGN NFIA PKHD1 SDK1 WWC1	1.14e-06	189	126	7	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	TRIM2 INSR GLIS3 CCNO MAGI2 NFIA WWC1	1.18e-06	190	126	7	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPR19 PAK5 SLC5A7 CLASP2 PCDH17 NSG2 ZFR2	1.27e-06	192	126	7	2f1c4ef693515ccc7231bd8c6641fad51d445d20
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 INSR GLIS3 MAGI2 PKHD1 SDK1 VPS13B	1.27e-06	192	126	7	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Neuronal-CFuPNs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	DOK6 ANK3 PAK5 RGS7 PCDH17 NSG2 CTNND2	1.41e-06	195	126	7	574354ef4bcefeb9856b65d19bb92e2cffe5dc7a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM2 ANK3 GLIS3 PTGER3 ZNRF3 PKHD1 WWC1	1.46e-06	196	126	7	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM2 ANK3 GLIS3 PTGER3 ZNRF3 PKHD1 WWC1	1.46e-06	196	126	7	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	DOK6 COL12A1 PRICKLE1 GLIS3 MAGI2 UNC5C SDK1	1.51e-06	197	126	7	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	INSRR SLC5A7 GDF2 PTGER3 FSIP2	3.65e-06	82	126	5	cefd8c6f60ef27fb8823faddca1cf8bbd636f474
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Ngfr_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	INSRR SLC5A7 GDF2 PTGER3 FSIP2	3.65e-06	82	126	5	1ed7d7f70f00d6e280cd59c54e710bb724c8b50b
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Ngfr_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	INSRR SLC5A7 GDF2 PTGER3 FSIP2	3.65e-06	82	126	5	a5d3c5b7012d8ca7418670242d22aad3ed8c5191
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 SLC5A7 FIGN PCDH17 UNC5C PDE7B	6.61e-06	161	126	6	1b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LZTS3 HJURP F8 PCDH17 DDIAS TPX2	7.09e-06	163	126	6	3efbbdc9cb2613bb76d8c2f07cd4ec1a2c51a622
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Brinp3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PAK5 OBSCN NEFL NFIA QPCT EPHB1	7.09e-06	163	126	6	b0aa4a620bd58011225b42ea6dda04e3101ba342
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Gpc3_Slc18a3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VAX1 FKBP9 SLC5A7 PCDH17 ACKR3 QPCT	7.09e-06	163	126	6	ec9a20cfe0d69430f9c68cddd1ab0e4a3e4554b8
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAK5 SLC5A7 RGS7 PCDH17 NEFL NSG2	1.10e-05	176	126	6	04dad262929581872e5bbc66cd8182c963e7e52f
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GPLD1 TRIM2 ANK3 PCDH17 RNF145 WWC1	1.17e-05	178	126	6	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	GPLD1 TRIM2 INSRR TBC1D9 NSG2 AKAP11	1.21e-05	179	126	6	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 PRICKLE1 FNDC3A PTGER3 TBC1D9 PDE7B	1.21e-05	179	126	6	d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A PRICKLE1 DCBLD1 FIGN F8 PCDH17	1.29e-05	181	126	6	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 SLCO1B1 MAGI2 ZNRF3 PKHD1 WWC1	1.29e-05	181	126	6	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	TRIM2 ANK3 GLIS3 ROS1 RNF145 SDK1	1.29e-05	181	126	6	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 SLCO1B1 MAGI2 ZNRF3 PKHD1 WWC1	1.33e-05	182	126	6	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GABRB1 PAK5 PTGER3 RGS7 NSG2 QPCT	1.33e-05	182	126	6	27a27a3eaeacb087c9601d5bb1c9e57cdfcd9d77
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SETD1B PAK5 SLC35E2B ARID3B SDK1	1.35e-05	107	126	5	410b37beffaf637a2a64c9d0ce7baf81f4bc667c
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SETD1B PAK5 SLC35E2B ARID3B SDK1	1.35e-05	107	126	5	5bae4b3aede9bcbf7e88414e3453973cc8b0c3e7
ToppCell	Adult-Mesenchymal-pericyte_cell-D122\|Adult / Lineage, Cell type, age group and donor	DOK6 OBSCN FIGN UNC5C DOCK6 TBX5	1.37e-05	183	126	6	fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	DOK6 GLIS3 FIGN NFIA PKHD1 WWC1	1.41e-05	184	126	6	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DOK6 OBSCN FIGN UNC5C DOCK6 TBX5	1.50e-05	186	126	6	888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOK6 PRICKLE1 INSR FIGN PKHD1 SDK1	1.50e-05	186	126	6	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK3 ZNRF3 ROS1 DMBT1 RNF145 WWC1	1.50e-05	186	126	6	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 PRICKLE1 NFIA PKHD1 SDK1 WWC1	1.50e-05	186	126	6	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPR19 ABCA12 PAK5 SLC5A7 CLASP2 RGS7	1.50e-05	186	126	6	15f2e5905486e33f6f7b3b3e9758a0559e8c61ee
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	TRIM2 INSR GLIS3 CCNO MAGI2 NFIA	1.55e-05	187	126	6	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOK6 OBSCN SLCO1C1 UNC5C DOCK6 TBX5	1.55e-05	187	126	6	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPN3 FIGN CUZD1 PKHD1 DMBT1 WWC1	1.55e-05	187	126	6	9aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOK6 FIGN NFIA PKHD1 SDK1 WWC1	1.55e-05	187	126	6	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	COVID-19-kidney-CD-PC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK3 GLIS3 PTGER3 PKHD1 SDK1 WWC1	1.60e-05	188	126	6	8f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ANK3 CCNO ZNRF3 UBR5 EML1 SDK1	1.60e-05	188	126	6	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	IPF-Epithelial-Club\|IPF / Disease state, Lineage and Cell class	TRIM2 ANK3 GLIS3 ROS1 SDK1 WWC1	1.65e-05	189	126	6	f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCell	Mesenchymal-pericyte_cell\|World / Lineage, Cell type, age group and donor	DOK6 OBSCN SLCO1C1 UNC5C DOCK6 TBX5	1.65e-05	189	126	6	d7ed96add29f219183c802895fbff519b627f635
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DOK6 OBSCN SLCO1C1 UNC5C DOCK6 TBX5	1.70e-05	190	126	6	4eb92aef1ee868f4537483d19014d947b7684612
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DOK6 OBSCN SLCO1C1 UNC5C DOCK6 TBX5	1.70e-05	190	126	6	7be4341e2909101d756f14031c21e705eb45e69a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 PRICKLE1 NFIA PKHD1 SDK1 WWC1	1.75e-05	191	126	6	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 PRICKLE1 NFIA PKHD1 SDK1 WWC1	1.75e-05	191	126	6	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	367C-Epithelial_cells\|367C / Donor, Lineage, Cell class and subclass (all cells)	ANK3 CPB2 PKP3 ROS1 DMBT1 WWC1	1.75e-05	191	126	6	d31975fc33779b0b3ff1a50d7c64fec8d08be4d4
ToppCell	IPF-Epithelial-Club\|World / Disease state, Lineage and Cell class	TRIM2 ANK3 GLIS3 ROS1 SDK1 WWC1	1.75e-05	191	126	6	3c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRICKLE1 GLIS3 FIGN PKHD1 SDK1 WWC1	1.75e-05	191	126	6	1cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell	COVID-19-kidney-TAL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRIM2 GLIS3 PTGER3 PKHD1 PDE7B WWC1	1.75e-05	191	126	6	fe55475ce0666ab5122447a813dc2369e24947b8
ToppCell	10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FAT4 PDE2A PCDH17 EML1 BSN DOCK6	1.75e-05	191	126	6	dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCell	COVID-19-kidney-Mito-rich_Distal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRIM2 GLIS3 PTGER3 PKHD1 PDE7B WWC1	1.75e-05	191	126	6	0965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK3 ZNRF3 PKHD1 ROS1 DMBT1 WWC1	1.80e-05	192	126	6	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 PDE2A PRICKLE1 F8 PCDH17 DOCK6	1.85e-05	193	126	6	826b8dd801298b3e0cd76232feae5a14026b8806
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANK3 GLIS3 ZNRF3 ROS1 DMBT1 WWC1	1.85e-05	193	126	6	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	TRIM2 ANK3 GLIS3 CCNO RNF145 WWC1	1.85e-05	193	126	6	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 PDE2A PRICKLE1 F8 PCDH17 DOCK6	1.85e-05	193	126	6	87d3a577d37fb0cb4b6313c596310de452bc3872
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	DOK6 FAT4 COL12A1 MAGI2 UNC5C TBX5	1.85e-05	193	126	6	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 GLIS3 PTGER3 ZNRF3 PKHD1 WWC1	1.85e-05	193	126	6	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 PDE2A PRICKLE1 F8 PCDH17 DOCK6	1.85e-05	193	126	6	d485634c564b268e344b6a2863c26f6adaec9e38
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 GLIS3 PTGER3 ZNRF3 PKHD1 WWC1	1.85e-05	193	126	6	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	DOK6 FAT4 MAGI2 UNC5C SDK1 TBX5	1.85e-05	193	126	6	acad568621ed677031797b8c2e34dafea798d681
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANK3 GLIS3 ZNRF3 ROS1 DMBT1 WWC1	1.85e-05	193	126	6	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FAT4 GLIS3 MAGI2 UNC5C SDK1 TBX5	1.91e-05	194	126	6	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FAT4 DCBLD1 CLCN3 NFIA UNC5C TBX5	1.91e-05	194	126	6	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TERT PKP3 PKHD1 ROS1 CTNND2 WWC1	1.91e-05	194	126	6	c011cd59bb4ca4134331cba0f5d73bdbd7011d64
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM2 ANK3 PTGER3 ZNRF3 PKHD1 WWC1	1.91e-05	194	126	6	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	LPS-IL1RA-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT4 PCDH17 EML1 CTNND2 DOCK6 IL7R	1.91e-05	194	126	6	43f92b0533e26633dc94cce554045d641ef8fd76
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 GLIS3 PTGER3 ZNRF3 PKHD1 WWC1	1.91e-05	194	126	6	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	LPS-IL1RA-Endothelial-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT4 PCDH17 EML1 CTNND2 DOCK6 IL7R	1.91e-05	194	126	6	1d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	TRIM2 ANK3 GLIS3 NFIA SDK1 WWC1	1.96e-05	195	126	6	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FAT4 DCBLD1 MAGI2 NFIA UNC5C TBX5	1.96e-05	195	126	6	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRIM2 ANK3 CCNO CTNND2 RNF145 WWC1	1.96e-05	195	126	6	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	TRIM2 ANK3 GLIS3 NFIA SDK1 WWC1	1.96e-05	195	126	6	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	PCW_05-06-Mesenchymal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	DOK6 FAT4 MAGI2 NFIA UNC5C TBX5	2.02e-05	196	126	6	dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM2 ANK3 ZNRF3 PKHD1 SDK1 WWC1	2.02e-05	196	126	6	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	wk_08-11-Epithelial-PNS-TM4SF4+_PENK+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PAK5 SLC5A7 PTGER3 RGS7 NEFL NSG2	2.02e-05	196	126	6	afa3a2f5f3a51d1830c6f95f97a4b3e13ed42512
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAK5 SLC5A7 RGS7 PCDH17 NSG2 ZFR2	2.08e-05	197	126	6	5593721407f61fc5bc3f2f8bf8fa2604c4e29565
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAK5 SLC5A7 RGS7 PCDH17 NEFL NSG2	2.14e-05	198	126	6	85881637641d8996be2edc65c4bceff0433135e7
ToppCell	distal-Epithelial-Alveolar_Epithelial_Type_2-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANK3 CPB2 ROS1 DMBT1 RNF145 WWC1	2.14e-05	198	126	6	19eefd05573fbaed654af52bf0f8a26092b8b229
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRIM2 ANK3 INSR CCNO RNF145 WWC1	2.14e-05	198	126	6	af399569c718f5fd971d73a7926768c9311002a3
ToppCell	Control_saline-Endothelial-Endothelial-Activated_Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	COL12A1 PCDH17 TBC1D9 ARID3B DDIAS IL7R	2.14e-05	198	126	6	3c3a5d2555f6af4aa33f9ea778808315d0e39d86
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 GLIS3 MAGI2 SDK1 VPS13B GAB1	2.14e-05	198	126	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOK6 FAT4 MAGI2 NFIA UNC5C TBX5	2.14e-05	198	126	6	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	DOK6 FAT4 MAGI2 UNC5C SDK1 TBX5	2.20e-05	199	126	6	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	distal-1-Epithelial\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANK3 CPB2 PKP3 DMBT1 RNF145 WWC1	2.20e-05	199	126	6	9086dbb60863c3da2cc5d0a310f28596a01c52ca
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 CLASP2 MAGI2 UBR5 NFIA VPS13B	2.20e-05	199	126	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FAT4 COL12A1 PCDH17 UBR5 DOCK6 IL7R	2.26e-05	200	126	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Macroglial-Astrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GABRB1 GLIS3 SLCO1C1 ZNRF3 WWC1 EPHB1	2.26e-05	200	126	6	941536b7c32f1e63c70535233b2ccce0cd7bf96e
Drug	(S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; PC3; HT_HG-U133A	GPLD1 GPR19 FNDC3A PTGER3 SLCO1B1 RGS7 MAGI2 CTNND2 CXCR2	1.14e-06	196	122	9	4524_UP
Drug	Methacholine chloride [62-51-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A	SETD1A PDE2A TRIM2 GPR19 RAD54L2 CEP164 EML1 VPS13B	1.05e-05	195	122	8	3452_UP
Drug	Solanine alpha [20562-02-1]; Up 200; 4.6uM; HL60; HT_HG-U133A	GABRB1 ANK3 PAK5 SUN1 PCDH17 MFAP3 HOXC6 TBX5	1.05e-05	195	122	8	2152_UP
Drug	Timolol maleate salt [26921-17-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A	GPLD1 SETD1A UNC5C CUZD1 QPCT EML1 DOCK6 GAB1	1.09e-05	196	122	8	6483_UP
Drug	Acetopromazine maleate salt [3598-37-6]; Down 200; 9uM; PC3; HT_HG-U133A	GPR19 CCNO GAL3ST4 JUNB JMJD6 HSF1 DOCK6 KDM4B	1.09e-05	196	122	8	4494_DN
Drug	genistein; Up 200; 1uM; MCF7; HG-U133A	GPR19 LZTS3 FNDC3A CLASP2 MFAP3 CTNND2 WWC1 KDM4B	1.22e-05	199	122	8	268_UP
Drug	Esculin Hydrate [531-75-9]; Up 200; 11.8uM; HL60; HT_HG-U133A	FAT4 LZTS3 GAL3ST4 PTGER3 PCDH17 SLCO1C1 CACNA1I TBX5	1.22e-05	199	122	8	3052_UP
Drug	Pargyline hydrochloride [306-07-0]; Up 200; 20.4uM; MCF7; HT_HG-U133A	GAL3ST4 FNDC3A PTGER3 JMJD6 CACNA1I DMBT1 VPS13B TBX5	1.26e-05	200	122	8	2265_UP
Disease	polycystic ovary syndrome	GABRB1 CDK12 INSR FIGN ZNRF3 ACKR3 UNC5C	5.28e-09	60	121	7	EFO_0000660
Disease	neurodevelopmental disorder with speech impairment and dysmorphic facies (implicated_via_orthology)	SETD1A SETD1B	1.67e-05	2	121	2	DOID:0070417 (implicated_via_orthology)
Disease	sphingomyelin measurement	KIF16B APOB SLCO1B1 SENP1 ZNRF3 DOCK6 SDK1 ABCG8	2.01e-05	278	121	8	EFO_0010118
Disease	stomach cancer (is_marker_for)	CDK12 TERT UBR5 DOCK6 KDM4B EPHB1	2.73e-05	142	121	6	DOID:10534 (is_marker_for)
Disease	Adenocarcinoma of large intestine	CDK12 PAK5 ZNRF3 UBR5 ROS1	4.84e-05	96	121	5	C1319315
Disease	Cri-du-Chat Syndrome	TERT CTNND2	4.99e-05	3	121	2	C0010314
Disease	ceramide measurement	GABRB1 CDK12 KIF16B APOB SLCO1B1 SLCO1C1 SDK1	5.43e-05	235	121	7	EFO_0010222
Disease	melanoma	FAT4 DCBLD1 TERT JMJD6 QPCT ROS1 KDM4B	7.62e-05	248	121	7	C0025202
Disease	gallbladder carcinoma (is_implicated_in)	TERT UBR5	1.65e-04	5	121	2	DOID:4948 (is_implicated_in)
Disease	p-tau measurement	SUN1 GLIS3 UNC5C LRRFIP2	2.23e-04	72	121	4	EFO_0004763
Disease	hormone measurement, thyroid stimulating hormone measurement	INSR GLIS3 NFIA	2.27e-04	29	121	3	EFO_0004730, EFO_0004748
Disease	laryngeal carcinoma (is_marker_for)	UBR5 ACKR3	2.47e-04	6	121	2	DOID:2600 (is_marker_for)
Disease	hematocrit	INSR GLIS3 APOB GDF2 TERT CEP164 SENP1 ZNRF3 NFIA PKHD1 DMBT1 BSN TBX5	2.68e-04	1011	121	13	EFO_0004348
Disease	familial hyperlipidemia (is_implicated_in)	APOB ABCG8	4.59e-04	8	121	2	DOID:1168 (is_implicated_in)
Disease	Glioma	TERT CLCN3 ROS1 DMBT1	4.61e-04	87	121	4	C0017638
Disease	insomnia measurement	PDE2A GLIS3 WDR27 MARCHF7 UBR5 CTNND2 SDK1 KDM4B	4.97e-04	443	121	8	EFO_0007876
Disease	alcohol dependence (implicated_via_orthology)	INSR INSRR	5.89e-04	9	121	2	DOID:0050741 (implicated_via_orthology)
Disease	X-21467 measurement	SLCO1B1 SLCO1C1	5.89e-04	9	121	2	EFO_0020007
Disease	endometriosis	COL12A1 WDR27 ARID3B HOXC6 BSN VPS13B	6.20e-04	252	121	6	EFO_0001065
Disease	phosphatidylinositol measurement	APOB SLCO1B1 SLCO1C1 DOCK6	6.42e-04	95	121	4	EFO_0010230
Disease	diffusing capacity of the lung for carbon monoxide	INSR CEP164 NSG2 ZFR2	6.68e-04	96	121	4	EFO_0009369
Disease	facial morphology measurement	FAT4 PRICKLE1 GLIS3 MAGI2 PKHD1 CTNND2 PDE7B VPS13B	6.92e-04	466	121	8	EFO_0007841
Disease	pancreatic carcinoma	APOB TERT ZNRF3 ACKR3 DMBT1	7.71e-04	174	121	5	EFO_0002618
Disease	Gastric Adenocarcinoma	INSR ROS1 EPHB1	8.42e-04	45	121	3	C0278701
Disease	beta thalassemia (is_marker_for)	APOB TERT	8.95e-04	11	121	2	DOID:12241 (is_marker_for)
Disease	invasive ductal carcinoma (is_implicated_in)	NEFL UBR5	8.95e-04	11	121	2	DOID:3008 (is_implicated_in)
Disease	sleep disorder (implicated_via_orthology)	INSR INSRR	8.95e-04	11	121	2	DOID:535 (implicated_via_orthology)
Disease	total lipids in lipoprotein particles measurement	APOB DOCK6 ABCG8	1.02e-03	48	121	3	EFO_0022309
Disease	PR interval	ABCA12 SUN1 OBSCN FIGN MAGI2 NFIA CTNND2 TBX5	1.02e-03	495	121	8	EFO_0004462
Disease	Schizophrenia	GABRB1 SETD1A ANK3 GRM2 PTGER3 PCDH17 MAGI2 NEFL UNC5C CTNND2 PDE7B	1.04e-03	883	121	11	C0036341
Disease	urate measurement, bone density	MARCHF7 CLASP2 PCDH17 MEX3C FSIP2 DMBT1 CTNND2 LRRFIP2 EPHB1	1.05e-03	619	121	9	EFO_0003923, EFO_0004531
Disease	Cleft palate, cleft lip	VAX1 FIGN ARID3B PKHD1 SDK1 VPS13B	1.05e-03	279	121	6	EFO_0003959, HP_0000175
Disease	chronic kidney disease (implicated_via_orthology)	INSR TERT	1.07e-03	12	121	2	DOID:784 (implicated_via_orthology)
Disease	apolipoprotein B to apolipoprotein A1 ratio	APOB DOCK6 ABCG8	1.08e-03	49	121	3	EFO_0021897
Disease	mouth morphology measurement	RGS7 NFIA SDK1	1.15e-03	50	121	3	EFO_0007955
Disease	coronary artery disease	FAT4 CDK12 APOB FIGN SENP1 NFIA UNC5C PKHD1 EML1 BSN DOCK6 ABCG8 KDM4B	1.26e-03	1194	121	13	EFO_0001645
Disease	diet measurement	ANK3 PIGS GLIS3 APOB PTGER3 RGS7 PCDH17 MAGI2 MTMR2 PKHD1 CTNND2 SDK1	1.28e-03	1049	121	12	EFO_0008111
Disease	intelligence, self reported educational attainment	PCDH17 MTMR2 CACNA1I BSN	1.40e-03	117	121	4	EFO_0004337, EFO_0004784
Disease	diabetic neuropathy (implicated_via_orthology)	INSR INSRR	1.47e-03	14	121	2	DOID:9743 (implicated_via_orthology)
Disease	neuroimaging measurement	ANK3 PAK5 GLIS3 NEFL ZNRF3 NFIA ACKR3 MTMR2 PKHD1 EML1 WWC1 KDM4B	1.50e-03	1069	121	12	EFO_0004346
Disease	ecosanoids measurement	SLCO1B1 SLCO1C1 ABCG8	1.51e-03	55	121	3	EFO_0020044
Disease	response to statin, LDL cholesterol change measurement	APOB SLCO1B1	1.69e-03	15	121	2	EFO_0007804, GO_0036273
Disease	hepatic encephalopathy (biomarker_via_orthology)	GABRB1 INSR	1.69e-03	15	121	2	DOID:13413 (biomarker_via_orthology)
Disease	alcohol consumption measurement	SETD1A COL12A1 CDK12 PTGER3 MAGI2 NFIA PKHD1 AKAP11 CACNA1I CTNND2 SDK1 ABCG8 WWC1	1.78e-03	1242	121	13	EFO_0007878
Disease	Calcium channel blocker use measurement	INSR GLIS3 FIGN MEX3C HOXC6	1.89e-03	213	121	5	EFO_0009930
Disease	vision disorder	MAGI2 SDK1	1.93e-03	16	121	2	MONDO_0021084
Disease	response to acetylsalicylate	DOK6 EPHB1	1.93e-03	16	121	2	GO_1903492
Disease	oral squamous cell carcinoma (is_marker_for)	NAIP JUNB DOCK6	2.23e-03	63	121	3	DOID:0050866 (is_marker_for)
Disease	neutrophil count, basophil count	MARCHF7 PCDHA1 TERT ACKR3 CXCR2	2.35e-03	224	121	5	EFO_0004833, EFO_0005090
Disease	bilirubin measurement	FAT4 HJURP APOB SLCO1B1 SLCO1C1 DMBT1 EPHB1	2.36e-03	442	121	7	EFO_0004570
Disease	Adrenocortical carcinoma	TERT ZNRF3	2.44e-03	18	121	2	C0206686
Disease	Hypercholesterolemia, Familial	APOB ABCG8	2.44e-03	18	121	2	C0020445
Disease	cardiovascular disease	INSR APOB FIGN MEX3C UNC5C PKHD1 ABCG8	2.84e-03	457	121	7	EFO_0000319
Disease	Nonorganic psychosis	ANK3 PAK5 WWC1	2.89e-03	69	121	3	C0349204
Disease	Malignant Glioma	TERT CLCN3 ROS1	3.01e-03	70	121	3	C0555198
Disease	mixed gliomas	TERT CLCN3 ROS1	3.01e-03	70	121	3	C0259783
Disease	age at menarche	CPA5 FNDC3A GRM2 MAGI2 MFAP3 BSN PDE7B KDM4B	3.17e-03	594	121	8	EFO_0004703
Disease	myocardial infarction	DOK6 DCBLD1 APOB FIGN UNC5C DMBT1	3.27e-03	350	121	6	EFO_0000612
Disease	esophagus squamous cell carcinoma (is_marker_for)	TERT JUNB HOXB7	3.53e-03	74	121	3	DOID:3748 (is_marker_for)
Disease	cortical surface area measurement	TRIM2 ANK3 GLIS3 GAL3ST4 MARCHF7 NFIA ACKR3 UNC5C MTMR2 PKHD1 EML1 WWC1 EPHB1	3.54e-03	1345	121	13	EFO_0010736
Disease	lung carcinoma	GPLD1 DCBLD1 TERT RGS7 SENP1 DEPDC7 EPHB1	3.80e-03	482	121	7	EFO_0001071
Disease	Alzheimer disease	ANK3 PRICKLE1 MTMR2 PKHD1 PDE7B SDK1 WWC1	3.93e-03	485	121	7	MONDO_0004975
Disease	goiter	INSR NFIA	3.99e-03	23	121	2	EFO_0004283
Disease	Parkinson's disease (implicated_via_orthology)	PAK5 INSR INSRR HSF1	4.05e-03	157	121	4	DOID:14330 (implicated_via_orthology)
Disease	schizophrenia (is_implicated_in)	ANK3 CACNA1I CTNND2	4.09e-03	78	121	3	DOID:5419 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
SAYNNFLNYVSSLPS	NAIP	786	Q13075
YSSSLFGYSPAAATA	ARID3B	331	Q8IVW6
YDLSPSRSHTSSNYD	CDK12	246	Q9NYV4
AELSLADYAFTSYSP	CCNO	266	P22674
ADYAFTSYSPSLLAI	CCNO	271	P22674
LSPTAFSYASQYIAR	ABCA12	1211	Q86UK0
YNSSSSSPRYTSDLE	EPN3	186	Q9H201
SYPISDFASYFQSLD	GRM2	321	Q14416
SSSASKPTLYSIYNA	GPR19	321	Q15760
NDNAPRFSRTSYYLD	FAT4	2866	Q6V0I7
RLFSSESDNSLYFTY	ABCG8	26	Q9H221
PYRNEVSQLYSFSTS	AKAP11	1446	Q9UKA4
YSPARYADALFKSSD	DEPDC7	151	Q96QD5
SYAQYYPASDQSLTS	RAD54L2	986	Q9Y4B4
AAAAAALYYSSSTLP	CTNND2	246	Q9UQB3
YSAARPYSELNYETS	CTNND2	1201	Q9UQB3
PASFSSLYNSYVESE	ARMCX2	551	Q7L311
SSAPQVAAAYTFYAL	ABHD8	216	Q96I13
PSKYSSLIYFDSSAT	HJURP	381	Q8NCD3
SFYSADTKSPDYVSQ	KIF16B	61	Q96L93
GPNFSLSDLESSSYY	NFIA	241	Q12857
YRTQSSASLAASYAA	RBM14	516	Q96PK6
NDNAPAFSRTSYSTY	PCDHGA2	446	Q9Y5H1
AFSRTSYSTYIPENN	PCDHGA2	451	Q9Y5H1
EASSQYLPTDSQYLS	PCDH17	1066	O14917
SQTPYGYRSFSNIIS	QPCT	111	Q16769
DLYNRYTSDKSTTPA	GDF2	91	Q9UK05
RASSSSPLDYSFQFT	PAK5	221	Q9P286
SRYLQDDTSDPTYTS	EPHB1	766	P54762
YNGTSNLSSYSYPSA	FIGN	236	Q5HY92
YYESFSLSPAAVADN	JMJD6	31	Q6NYC1
PSYSRFYESGSSLRA	HDX	321	Q7Z353
RNSLTSLPTYSSSYS	LZTS3	221	O60299
PRSDYATYTNSNHAA	MAGI2	886	Q86UL8
SSTSASFTDLYYDPF	WWC1	456	Q8IX03
SASVDSSLYNLPRSY	GAB1	251	Q13480
YYASSLQSGVPSRFS	IGKV1D-43	71	A0A0B4J1Z2
SSAEYSQPSRASSAY	BSN	3701	Q9UPA5
RLERSTNSFSYSSYH	CPA5	126	Q8WXQ8
SPRYAISQAYSYVDS	FSIP2	2596	Q5CZC0
AYSSSSLYAPDAVAS	HSF1	246	Q00613
IDSNFASFTYTPRSL	PDE2A	596	O00408
RYHTNNYASSSTSLP	PTGER3	361	P43115
YPFIDFRLLNSTTYS	PDE7B	46	Q9NP56
SNYSYSSTLPPFLLD	CXCR2	21	P25025
EYFLPNPYLSALSSS	DDIAS	531	Q8IXT1
SLDAYYSSQDPNSRS	NSG2	116	Q9Y328
SYSDNLYPESITSRD	KDM4B	956	O94953
SQLEDFTNPLYGSYS	MTMR2	546	Q13614
YSYLSDFETPQSSGR	LCA5	21	Q86VQ0
SYDSASIQYRKPLSS	GABRB1	396	P18505
SPSYYFRTPEINNSS	IL7R	221	P16871
NQASRPYSFYSSLIS	F8	1796	P00451
LYASSNPEYLSASDV	INSR	991	P06213
PAALARSAFSYYKST	GAL3ST4	161	Q96RP7
SAYYTRQSSSLYSDP	LRRFIP2	166	Q9Y608
RQSSSLYSDPLATYK	LRRFIP2	171	Q9Y608
NRSSYNASFPSSFEL	MFAP3	36	P55082
ALLTYTLSPSDYFSL	PCDHA1	166	Q9Y5I3
YANTLFSKYPASSSV	HOXB7	6	P09629
LNSTAYDPVRHFSTY	HOXC6	26	P09630
ESSSYFSAQGYLSSR	OBSCN	5231	Q5VST9
FAYYTDDLSSPPSAL	PRICKLE1	791	Q96MT3
DSSYSRNRTFDTYIG	FKBP9	296	O95302
YSNASSTDSASYYPL	APOB	981	P04114
RYQYLSAAYSPVTTD	DOCK6	126	Q96HP0
ISNDTVSPRASASYY	CPB2	106	Q96IY4
SLESGSFPSYSAYRI	COL12A1	2541	Q99715
AQQPLSRSSSYGFSY	DOK6	311	Q6PKX4
YKGPDSSFRYSSLQL	FNDC3A	1096	Q9Y2H6
SYDQRSLSSSRSSYY	CACNA1I	961	Q9P0X4
DLYSAPIFSSNYSSR	GLIS3	551	Q8NEA6
AVSYDSSASQFPNYL	FAM120C	496	Q9NX05
DRYLSITYFTNTPSS	ACKR3	141	P25106
SFSSDRSYTLNRSSY	ANK3	916	Q12955
DFTTSSYVQDRVPSY	MARCHF7	166	Q9H992
TLYASVNPEYFSASD	INSRR	951	P14616
RGFSYPSNLVYSTDL	KRTAP13-2	26	Q52LG2
SSYSSLYDTSSLLQF	EML1	6	O00423
SASRSSLDLSYYPTS	EMD	171	P50402
VLSTDYANSYRGFSA	CUZD1	246	Q86UP6
SDYLLFTSSSDQYGP	DCBLD1	96	Q8N8Z6
YPYFEALNISSRESS	C4orf54	636	D6RIA3
RAEYYSSPSNDSTNL	DMBT1	2111	Q9UGM3
YQIAYRLASSSPHTF	SDK1	1411	Q7Z5N4
TYSFSPSKSYSRQSS	C2CD5	291	Q86YS7
IYTYLRPSSSYSLNQ	OR5F1	256	O95221
SFIYLRPQSNYSSSQ	OR10K2	256	Q6IF99
GVNPRFDSASSSYYL	PIGS	281	Q96S52
AYFQRVLSSSSATYA	SLC5A7	256	Q9GZV3
NYFESYLAVASTVPS	SLC29A3	101	Q9BZD2
NFVSSSSRSKYIPLY	SPATA48	311	A4D263
KSDSYPRFIRSSAYQ	RGS7	431	P49802
SPSEEDSFYRSSYPQ	TBX5	346	Q99593
YIPAFSNGTNSYSSS	MEX3C	576	Q5U5Q3
STRSAAYNPSYYSDN	SENP1	61	Q9P0U3
DSSYSSRQPTPSYLF	SETD1B	286	Q9UPS6
DYSAVLPRAFTYVSS	PKHD1	1091	P08F94
SSQFRSSDANYPAYY	SETD1A	356	O15047
YNSTSFSRVYLGLSS	SLCO1B1	616	Q9Y6L6
TPTYYGSLARFSALS	CEP164	1311	Q9UPV0
RNDLSTSFENDYYPS	C12orf40	386	Q86WS4
TSFENDYYPSSSERK	C12orf40	391	Q86WS4
SRDYNPYNYSDSISP	CLASP2	1016	O75122
YYRNSYNSITSASSD	CLCN3	11	P51790
AYTAAYSATLPSALS	C15orf62	101	A8K5M9
QLEPAATSTYRAFAY	PKP3	201	Q9Y446
PFASEVSSYSYNTDS	TNRC18	1721	O15417
RSLSTSQTFYDAYIS	TLR8	871	Q9NR97
SFYYQALSGDPSIQT	TMEM256	81	Q8N2U0
SAAARSYEDRPYFQS	ZFR2	96	Q9UPR6
SYEDRPYFQSAALQS	ZFR2	101	Q9UPR6
SFRPYRAEDNDSYAS	SOGA1	566	O94964
YKYERYSPSSNSTLS	SLCO1C1	136	Q9NYB5
YNSSDDEVYSRPSSL	TBC1D9	416	Q6ZT07
SSPLASYFLSFPYAR	GPLD1	366	P80108
APQRLLYYDSYTSSV	TRGV4	61	A0A0C4DH28
YSTLPNTIYRFSIAA	ROS1	251	P08922
YRFSAPELQFYTSAA	SLC35E2B	251	P0CK96
SRRFNSQSTSYLPGY	MRPL21	36	Q7Z2W9
FTYLTNSLFDYRSPE	VPS13B	491	Q7Z7G8
FRSSLSSDYDPFIYR	ZNRF3	586	Q9ULT6
SLTQLNSYFSDPSAY	TASOR2	256	Q5VWN6
NSYFSDPSAYILEVS	TASOR2	261	Q5VWN6
PENTGYTYALSSSYS	SUN1	16	O94901
RFSSFLSRSDSYGYL	TRAV1-1	76	A0A0B4J248
YSSSVLSAYPLLSLF	WDR27	201	A2RRH5
SFLSYINTSADPLYG	TRIM2	701	Q9C040
LQIYSYFSTRDQPAS	RNF145	241	Q96MT1
DRYLNYFATKSSPTG	UNC5C	876	O95185
YSSYARTSIRASLTF	TERT	946	O14746
SYLTSASSLARAYSI	UBR5	1776	O95071
LSARYLSSSAFEPYS	VAX1	306	Q5SQQ9
SSYSYDAPSDFINFS	TPX2	6	Q9ULW0
VYTNLSSYSPASASS	JUNB	181	P17275
ARSAYSSYSAPVSSS	NEFL	36	P07196