Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA1 ATP11B ATP9B

1.16e-0428683GO:0140326
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK8 OBSCN DENND5A HERC1 VAV2 MADD

1.35e-04231686GO:0005085
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DOCK8 OBSCN RACGAP1 TSC2 DENND5A HERC1 VAV2 MADD

3.17e-04507688GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

DOCK8 OBSCN RACGAP1 TSC2 DENND5A HERC1 VAV2 MADD

3.17e-04507688GO:0030695
GeneOntologyMolecularFunctionphosphatidylserine floppase activity

ABCA1 ATP11B

4.05e-049682GO:0090556
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCA1 ATP11B ATP9B

7.00e-0451683GO:0140303
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA1 ERCC6 ATP11B DYNC2H1 ATP9B VCP DNAH11

7.42e-04441687GO:0016887
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

ABCA1 DOCK8 OBSCN LRP4 RACGAP1 TSC2 VAV2 MADD

1.35e-05333688GO:0051056
GeneOntologyCellularComponentpresynaptic active zone membrane

STX1A LRFN1 P2RX1 TENM3

1.15e-0478674GO:0048787
MousePhenoabnormal lung morphology

ZSWIM8 FAT4 ABCA1 CCDC124 DYNC2H1 SPTBN1 LRP4 TSC2 EZH2 THOC2 RCN3 MADD DNAH11

9.55e-067675713MP:0001175
MousePhenoabnormal heart size

IL24 RHPN1 ZSWIM8 ABCA1 TENM4 CCDC124 TKT SPTBN1 TSC2 SHLD1 EZH2 THOC2 VAV2 DNAH11 SMTN

5.35e-0511805715MP:0005406
DomainRhs_assc_core

TENM4 TENM3

3.91e-053682IPR022385
DomainTox-GHH_dom

TENM4 TENM3

7.80e-054682IPR028916
DomainTen_N

TENM4 TENM3

7.80e-054682IPR009471
DomainTen_N

TENM4 TENM3

7.80e-054682PF06484
DomainTENEURIN_N

TENM4 TENM3

7.80e-054682PS51361
DomainTox-GHH

TENM4 TENM3

7.80e-054682PF15636
DomainYD

TENM4 TENM3

1.30e-045682IPR006530
DomainDHC_N1

DYNC2H1 DNAH11

3.61e-048682PF08385
DomainDynein_heavy_dom-1

DYNC2H1 DNAH11

3.61e-048682IPR013594
Domain-

TENM4 TENM3 LRP4

3.84e-04396832.120.10.30
Domain6-blade_b-propeller_TolB-like

TENM4 TENM3 LRP4

6.26e-0446683IPR011042
DomainNHL

TENM4 TENM3

9.93e-0413682PS51125
DomainDynein_heavy_chain_D4_dom

DYNC2H1 DNAH11

1.16e-0314682IPR024317
DomainDynein_HC_stalk

DYNC2H1 DNAH11

1.16e-0314682IPR024743
DomainDynein_heavy_dom-2

DYNC2H1 DNAH11

1.16e-0314682IPR013602
DomainDHC_N2

DYNC2H1 DNAH11

1.16e-0314682PF08393
DomainMT

DYNC2H1 DNAH11

1.16e-0314682PF12777
DomainAAA_8

DYNC2H1 DNAH11

1.16e-0314682PF12780
DomainuDENN

DENND5A MADD

1.16e-0314682SM00800
DomainP_typ_ATPase_c

ATP11B ATP9B

1.16e-0314682IPR032630
DomainP-type_ATPase_N

ATP11B ATP9B

1.16e-0314682IPR032631
DomainATPase_dyneun-rel_AAA

DYNC2H1 DNAH11

1.16e-0314682IPR011704
DomainP-type_ATPase_IV

ATP11B ATP9B

1.16e-0314682IPR006539
DomainPhoLip_ATPase_C

ATP11B ATP9B

1.16e-0314682PF16212
DomainPhoLip_ATPase_N

ATP11B ATP9B

1.16e-0314682PF16209
DomainAAA_5

DYNC2H1 DNAH11

1.16e-0314682PF07728
DomainDHC_fam

DYNC2H1 DNAH11

1.33e-0315682IPR026983
DomainDynein_heavy_dom

DYNC2H1 DNAH11

1.33e-0315682IPR004273
DomainuDENN

DENND5A MADD

1.33e-0315682PF03456
DomainDynein_heavy

DYNC2H1 DNAH11

1.33e-0315682PF03028
DomainUDENN

DENND5A MADD

1.52e-0316682PS50946
DomainDDENN

DENND5A MADD

1.52e-0316682PS50947
DomainDENN

DENND5A MADD

1.52e-0316682SM00799
DomaindDENN

DENND5A MADD

1.52e-0316682SM00801
DomainDENN

DENND5A MADD

1.52e-0316682PF02141
DomaindDENN_dom

DENND5A MADD

1.52e-0316682IPR005112
DomainuDENN_dom

DENND5A MADD

1.52e-0316682IPR005113
DomaindDENN

DENND5A MADD

1.52e-0316682PF03455
DomainDENN

DENND5A MADD

1.52e-0316682PS50211
DomainDENN_dom

DENND5A MADD

1.52e-0316682IPR001194
Domain-

MDP1 ATP11B ATP9B

1.64e-03646833.40.50.1000
DomainCarboxyPept-like_regulatory

TENM4 TENM3

1.71e-0317682IPR008969
DomainCH

SPTBN1 VAV2 SMTN

1.72e-0365683SM00033
DomainAAA+_ATPase

ABCA1 DYNC2H1 VCP DNAH11

1.88e-03144684IPR003593
DomainAAA

ABCA1 DYNC2H1 VCP DNAH11

1.88e-03144684SM00382
DomainCH

SPTBN1 VAV2 SMTN

2.12e-0370683PF00307
Domain-

SPTBN1 VAV2 SMTN

2.21e-03716831.10.418.10
DomainCH

SPTBN1 VAV2 SMTN

2.39e-0373683PS50021
DomainCH-domain

SPTBN1 VAV2 SMTN

2.58e-0375683IPR001715
DomainHAD-like_dom

MDP1 ATP11B ATP9B

3.00e-0379683IPR023214
DomainARM-like

DOCK8 DAAM2 NBEA TSC2 TRIP12

3.02e-03270685IPR011989
DomainHECT

HERC1 TRIP12

4.32e-0327682PF00632
DomainHECTc

HERC1 TRIP12

4.32e-0327682SM00119
DomainHECT_dom

HERC1 TRIP12

4.32e-0327682IPR000569
DomainHECT

HERC1 TRIP12

4.32e-0327682PS50237
DomainWD40_repeat_dom

TENM3 PPP2R2D NBEA WDR90 HERC1

4.53e-03297685IPR017986
DomainATP_grasp_subdomain_2

ACACA TTLL4

5.67e-0331682IPR013816
Domain-

ATP11B ATP9B

6.04e-03326823.40.1110.10
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

RHPN1 NR2F6 LRFN1 ACACA KLHL21 TTLL4 OBSCN LRP3 LRP4 TSC2 WDR90 DENND5A HERC1 MADD AHNAK2

2.84e-091105681535748872
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

ERCC6 ACACA CAPN7 U2SURP SPTBN1 OBSCN NBEA HERC1 TRIP12

5.40e-0749768936774506
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

GRAMD1B CCDC124 HLA-A BCAS2 SPTBN1 LRP4 RACGAP1 TSC2 SLC15A3 THOC2 VCP AHNAK2 SMTN

3.73e-061440681330833792
Pubmed

TGFβ1-RCN3-TGFBR1 loop facilitates pulmonary fibrosis by orchestrating fibroblast activation.

EZH2 RCN3

3.77e-06268237710230
Pubmed

Chromosomal mapping of two members of the human dynein gene family to chromosome regions 7p15 and 11q13 near the deafness loci DFNA 5 and DFNA 11.

DYNC2H1 DNAH11

3.77e-0626829325061
Pubmed

MicroRNA Let-7c-5p-Mediated Regulation of ERCC6 Disrupts Autophagic Flux in Age-Related Cataract via the Binding to VCP.

ERCC6 VCP

3.77e-06268233703976
Pubmed

Teneurins assemble into presynaptic nanoclusters that promote synapse formation via postsynaptic non-teneurin ligands.

TENM4 TENM3

3.77e-06268235484136
Pubmed

Histone Methyltransferase Enhancer of Zeste Homolog 2-Mediated ABCA1 Promoter DNA Methylation Contributes to the Progression of Atherosclerosis.

ABCA1 EZH2

3.77e-06268227295295
Pubmed

Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.

DYNC2H1 NBEA VAV2

5.71e-061868327984743
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

EXOC3L4 TTLL4 SPTBN1 OBSCN GPATCH8 HERC1 THOC2 TRIP12 SLC1A3 MADD SMTN

7.73e-061084681111544199
Pubmed

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.

GRAMD1B PDE4D SPTBN1 SLC1A3 MADD

1.06e-0514768516959763
Pubmed

TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase.

TSC2 HERC1

1.13e-05368216464865
Pubmed

Polycomb Protein Eed is Required for Neurogenesis and Cortical Injury Activation in the Subventricular Zone.

EZH2 SLC1A3

1.13e-05368229415247
Pubmed

The SLC34A2-ROS-HIF-1-induced up-regulation of EZH2 expression promotes proliferation and chemo-resistance to apoptosis in colorectal cancer.

SLC34A2 EZH2

1.13e-05368230038060
Pubmed

Long intergenic non-coding RNA 00152 promotes lung adenocarcinoma proliferation via interacting with EZH2 and repressing IL24 expression.

IL24 EZH2

1.13e-05368228109288
Pubmed

Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway.

TSC2 EZH2

1.13e-05368226735435
Pubmed

A new homozygous HERC1 gain-of-function variant in MDFPMR syndrome leads to mTORC1 hyperactivation and reduced autophagy during cell catabolism.

TSC2 HERC1

1.13e-05368232921582
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NR2F6 ACACA TKT SPTBN1 GPATCH8 EZH2 THOC2 TRIP12 SMTN

1.95e-0577468915302935
Pubmed

Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.

TENM4 TENM3

2.25e-05468210225957
Pubmed

Spatial distribution and developmental appearance of postjunctional P2X1 receptors on smooth muscle cells of the mouse vas deferens.

STX1A P2RX1

2.25e-05468211668586
Pubmed

Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.

DYNC2H1 OBSCN

2.25e-05468226147384
Pubmed

The p97 ATPase dislocates MHC class I heavy chain in US2-expressing cells via a Ufd1-Npl4-independent mechanism.

HLA-A VCP

2.25e-05468220702414
Pubmed

All four members of the Ten-m/Odz family of transmembrane proteins form dimers.

TENM4 TENM3

2.25e-05468212000766
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

ACACA PPP2R2D DYNC2H1 TKT SPTBN1 DAAM2 VAV2 VCP AHNAK2

2.70e-0580768930575818
Pubmed

Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development.

DYNC2H1 NBEA VAV2

3.09e-053168325838543
Pubmed

Functional specialization of beta-arrestin interactions revealed by proteomic analysis.

PDE4D ACACA SPTBN1 LRP4 CPA1 VCP

3.72e-0531768617620599
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ZSWIM8 STX1A HLA-A SPTBN1 LRP4 DAAM2 NBEA TSC2 TRIP12 VCP MADD

3.72e-051285681135914814
Pubmed

Candidate gene susceptibility variants predict intermediate end points but not angiographic coronary artery disease.

ABCA1 HLA-A

3.75e-05568216086925
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP3 LRP4

3.75e-05568219047013
Pubmed

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

ABCA1 MADD DNAH11

4.10e-053468319060911
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

LRFN1 TENM3 PPP2R2D RACGAP1

5.11e-0510368410819331
Pubmed

EZH2 K63-polyubiquitination affecting migration in extranodal natural killer/T-cell lymphoma.

EZH2 TRIP12

5.62e-05668238031139
Pubmed

USP7-mediated deubiquitination differentially regulates CSB but not UVSSA upon UV radiation-induced DNA damage.

ERCC6 VCP

5.62e-05668231775559
Pubmed

Valosin-containing Protein (VCP)/p97 Segregase Mediates Proteolytic Processing of Cockayne Syndrome Group B (CSB) in Damaged Chromatin.

ERCC6 VCP

5.62e-05668226826127
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ERCC6 ACACA TKT BCAS2 U2SURP SPTBN1 RACGAP1 TRIP12 VCP AHNAK2 SMTN

5.93e-051353681129467282
Pubmed

Common genetic variation and the control of HIV-1 in humans.

DDR1 HLA-A NBEA

6.71e-054068320041166
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

GRAMD1B STX1A TENM4 ACACA U2SURP SPTBN1 NBEA SLC1A3 VCP MADD

7.07e-051139681036417873
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

PDE4D ERCC6 TENM3 DYNC2H1 BCAS2 EZH2

7.30e-0535868632460013
Pubmed

The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles.

TENM4 TENM3

7.86e-05768210625539
Pubmed

The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.

TENM4 TENM3

7.86e-05768212915301
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ATP11B PPP2R2D KLHL21 TTLL4 LRP4 RACGAP1 WDR90

7.87e-0552968714621295
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

GRAMD1B PDE4D TENM4 DOCK8 TKT SPTBN1 NBEA SLC1A3 VCP MADD DNAH11

9.77e-051431681137142655
Pubmed

Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.

TENM4 TENM3

1.05e-04868210331952
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

FAT4 LRFN1 ACACA DYNC2H1 BCAS2 KLHL21 SPTBN1 VAV2

1.10e-0475468835906200
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

TKT U2SURP SPTBN1 RACGAP1 EZH2 TRIP12

1.23e-0439468627248496
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

U2SURP LRP4 TRIP12 MADD

1.26e-0413068412421765
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

ACACA TKT BCAS2 U2SURP RACGAP1 GPATCH8 THOC2 TRIP12 VCP

1.28e-0498968936424410
Pubmed

Daam2-PIP5K is a regulatory pathway for Wnt signaling and therapeutic target for remyelination in the CNS.

DAAM2 SLC1A3

1.34e-04968225754822
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

GRAMD1B TENM4 TENM3 DAAM2 GPATCH8 MADD

1.47e-0440768612693553
Pubmed

The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease.

ATP11B ATP9B

1.68e-041068215919184
Pubmed

Analysis of recently identified osteoporosis susceptibility genes in Han Chinese women.

SPTBN1 LRP4

1.68e-041068220554715
Pubmed

Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.

TENM4 TENM3

1.68e-041068238713721
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

USP30 ACACA HLA-A PPP2R2D DYNC2H1 TSC2 SLC1A3

1.82e-0460668736538041
Pubmed

Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma.

FAT4 EZH2

2.05e-041168224349473
Pubmed

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation.

HLA-A VCP

2.05e-041168224807418
Pubmed

Bimodal regulation of the PRC2 complex by USP7 underlies tumorigenesis.

SPTBN1 EZH2

2.05e-041168233849069
Pubmed

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

DDR1 TSC2 BCL2L2 PFKFB4 EZH2

2.10e-0427668528319085
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

ACACA ATP9B GPATCH8 DNAH11

2.30e-0415268434299191
Pubmed

RNA profiling and chromatin immunoprecipitation-sequencing reveal that PTF1a stabilizes pancreas progenitor identity via the control of MNX1/HLXB9 and a network of other transcription factors.

P2RX1 CPA1

2.45e-041268222232429
Pubmed

HIV Nef: role in pathogenesis and viral fitness.

HLA-A VAV2

2.45e-041268218473783
Pubmed

A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation.

HLA-A VCP

2.45e-041268221636303
Pubmed

ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner.

ATP11B ATP9B

2.45e-041268221914794
Pubmed

AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress.

ACACA TSC2

2.45e-041268221436046
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ZSWIM8 ACACA U2SURP SPTBN1 THOC2 TRIP12 VCP

2.86e-0465368722586326
Pubmed

Differential expression of putative transbilayer amphipath transporters.

ATP11B ATP9B

2.90e-041368211015572
Pubmed

HIV-1 Nef: hacker of the host cell.

HLA-A VAV2

2.90e-041368223847689
Pubmed

The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning.

DYNC2H1 DNAH11

2.90e-041368217884984
Pubmed

Quantification of synapse formation and maintenance in vivo in the absence of synaptic release.

STX1A VCP

2.90e-041368215145078
Pubmed

Tsc1 Haploinsufficiency Leads to Pax2 Dysregulation in the Developing Murine Cerebellum.

TSC2 SLC1A3

2.90e-041368235645731
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

ZSWIM8 TENM4 PPP2R2D SPTBN1 VCP MADD

3.37e-0447568631040226
Pubmed

New sequence variants associated with bone mineral density.

SPTBN1 LRP4

3.38e-041468219079262
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DYNC2H1 DNAH11

3.38e-04146829373155
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK8 RACGAP1

3.38e-041468212432077
Pubmed

A neurogenomics approach to gene expression analysis in the developing brain.

THOC2 TRIP12 RCN3 MADD

3.52e-0417068415582152
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

ZSWIM8 ATP11B U2SURP TSC2 GPATCH8

3.75e-0431368538270169
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

PDE4D PPP2R2D TKT BCAS2 U2SURP RACGAP1 SHLD1 VCP SMTN

4.04e-04115568920360068
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

CCDC124 ACACA TKT BCAS2 U2SURP SPTBN1 TSC2 SLC1A3 VCP AHNAK2

4.08e-041415681028515276
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

ZSWIM8 STX1A SPTBN1 TSC2 WDR90 THOC2 MADD SMTN

4.38e-0492568828986522
Pubmed

Identification of cAMP analogue inducible genes in RAW264 macrophages.

ABCA1 SLC15A3

4.44e-041668211004510
Pubmed

Tissue distribution, ontogeny, and hormonal regulation of xenobiotic transporters in mouse kidneys.

ABCA1 SLC34A2

4.44e-041668219679677
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PDE4D ERCC6 RACGAP1 EZH2 THOC2 TRIP12

4.56e-0450368616964243
Pubmed

Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1.

DYNC2H1 DNAH11

5.03e-041768222357932
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

GRAMD1B FAT4 HLA-A TENM3 LRP4 TSC2 RCN3 VCP MADD

5.36e-04120168935696571
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

BCAS2 U2SURP SPTBN1 THOC2 TRIP12

5.46e-0434068524332808
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

HLA-A TTLL4 MID1 RACGAP1 GPATCH8 MADD SPDL1

5.71e-0473368734672954
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FAT4 ACACA EXOC3L4 OBSCN NBEA TSC2 TRIP12

5.85e-0473668729676528
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

CCDC124 TKT U2SURP SPTBN1 MADD AHNAK2

6.48e-0453868628524877
Pubmed

Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration-associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways.

ABCA1 ACACA TKT VCP

6.60e-0420168425192599
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZSWIM8 NBEA DENND5A

6.74e-048768312465718
Pubmed

Neonatal Respiratory Failure with Retarded Perinatal Lung Maturation in Mice Caused by Reticulocalbin 3 Disruption.

RCN3 VCP

7.00e-042068226252542
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

GRAMD1B ZSWIM8 ACACA ATP11B BCL2L2 DNAH11

7.41e-0455268610737800
Pubmed

USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.

ACACA U2SURP TRIP12

7.44e-049068335654790
Pubmed

HIV-1 Nef control of cell signalling molecules: multiple strategies to promote virus replication.

HLA-A VAV2

7.72e-042168212734410
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

ERCC6 RACGAP1 GPATCH8 EZH2

7.78e-0421068416565220
Pubmed

Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method.

ACACA SPTBN1

8.48e-042268218487259
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

GRAMD1B CCDC124 HLA-A SPTBN1 AHNAK2 SPDL1

8.59e-0456868637774976
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

ACACA HLA-A TKT BCAS2 RACGAP1 TSC2 GPATCH8 HERC1 VCP

8.62e-04128468917353931
Pubmed

The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease.

PDE4D HLA-A SLC1A3 DNAH11

9.24e-0422068424705354
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

CCDC124 ACACA HLA-A BCAS2 U2SURP RACGAP1 TRIP12 RCN3 VCP

9.25e-04129768933545068
Pubmed

Intestinal epithelial cells secrete exosome-like vesicles.

DPEP1 HLA-A

9.28e-042368211487543
InteractionTOP3B interactions

RHPN1 NR2F6 LRFN1 ACACA KLHL21 TTLL4 OBSCN LRP3 LRP4 RACGAP1 TSC2 WDR90 DENND5A HERC1 THOC2 MADD AHNAK2

4.33e-0614706717int:TOP3B
Cytoband10q11.23

FAM170B ERCC6

1.11e-033368210q11.23
GeneFamilyLow density lipoprotein receptors

LRP3 LRP4

6.20e-0413522634
GeneFamilyATPase phospholipid transporting

ATP11B ATP9B

8.32e-04155221210
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND5A MADD

2.33e-0325522504
CoexpressionGSE22886_CD8_TCELL_VS_BCELL_NAIVE_DN

IL24 DDR1 P2RX1 MID1 BCL2L2 SLC15A3 VAV2

8.29e-07198687M4429
CoexpressionGSE22886_TCELL_VS_BCELL_NAIVE_DN

IL24 DDR1 ABCA1 MID1 BCL2L2 VAV2

1.28e-05198686M4426
CoexpressionGSE360_L_DONOVANI_VS_T_GONDII_MAC_UP

GRAMD1B CAPN7 TTLL4 ATP9B DENND5A THOC2

1.31e-05199686M5233
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

PDE4D DYNC2H1 SPTBN1 SLC34A2 NBEA DNAH11

5.37e-07195686fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

PDE4D DYNC2H1 SPTBN1 SLC34A2 NBEA DNAH11

5.37e-07195686eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ABCA1 TENM3 DYNC2H1 LRP3 COL6A5 SLC1A3

6.05e-07199686a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAT4 ABCA1 PDE4D DYNC2H1 DAAM2

6.07e-06169685c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell10x5'-Liver-Myeloid_Mac-Intermediate_macrophages|Liver / Manually curated celltypes from each tissue

ABCA1 DENND5A SLC15A3 SLC1A3 VAV2

6.42e-0617168525e0333743affdb662223fb5220b8a61fa02ad9f
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM170B ABCA1 EXOC3L4 SLC15A3 SLC1A3

7.59e-0617768526bad614560609d318bfc9c235a698bca4e1c22c
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-7|TCGA-Prostate / Sample_Type by Project: Shred V9

LRFN1 ACACA PPP2R2D EZH2 VAV2

8.69e-06182685af16334fec2c757b03c84cf252d00e92fa81e4cd
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACBD7 LRP4 DAAM2 SLC1A3 SMTN

9.91e-0618768593c78fc7f126132eb84feb47be2c4e8c568b9e91
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TENM4 RACGAP1 EZH2 SPDL1 SMTN

1.02e-0518868595d0a796d62ce6d121e2028c378faffc14b35275
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TENM4 LRP4 DAAM2 COL6A5 SLC1A3

1.10e-0519168514057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FAT4 TENM4 TENM3 DOCK8 SLC1A3

1.13e-05192685d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RHPN1 DYNC2H1 NBEA WDR90 DNAH11

1.18e-051946854a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 DYNC2H1 NBEA HERC1 MADD

1.21e-051956853e519cffa6144a62b06124642a14c9ff39b76554
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)|Adult / Lineage, Cell type, age group and donor

GRAMD1B ABCA1 DOCK8 DENND5A SLC1A3

1.21e-0519568555e25f702af19146a161861cfd15f40bbda1dc35
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 DYNC2H1 NBEA HERC1 MADD

1.21e-051956857796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ABCA1 TENM3 DYNC2H1 COL6A5 SLC1A3

1.27e-05197685fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellBronchial_Brush-Epithelial|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

DDR1 DYNC2H1 SPTBN1 NBEA DNAH11

1.27e-05197685272c7f4e582ef57564450540242b0db766b78328
ToppCellPSB-critical-LOC-Epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DDR1 NR2F6 SPTBN1 SLC34A2 NBEA

1.34e-0519968558dcb0eedafa8629585dc99e53147e2287f49689
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TENM4 TENM3 LRP4 DAAM2 RCN3

1.37e-052006853c898e81444b001835c3f1bbc68183078701b135
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TENM4 TENM3 LRP4 DAAM2 RCN3

1.37e-052006853eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LRFN1 HLA-A DOCK8 RCN3

8.40e-05151684b698ddc74565d47892c09c3f16d78038da2dd5e7
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|390C / Donor, Lineage, Cell class and subclass (all cells)

IL24 SLC15A3 SLC1A3 SPDL1

9.30e-0515568415bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSWIM8 NR2F6 DYNC2H1 TTLL4

1.00e-0415868412661763d1c309106801cb710c04cd2b62d16cba
ToppCelldroplet-Fat-Scat-21m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 MID1 COL6A5 SLC15A3

1.00e-04158684c8df636412a08c570f235c34d4cff46924a9b11d
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSWIM8 NR2F6 DYNC2H1 TTLL4

1.00e-04158684e7db50d6dfaf7280a73a0d5b5aa4f43ea2762d72
ToppCelldroplet-Fat-Scat-21m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 MID1 COL6A5 SLC15A3

1.00e-04158684718eafcf8a171bb69b402dc9d69564c3521a62a9
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSWIM8 NR2F6 DYNC2H1 TTLL4

1.00e-041586840792c39e6fc0745095af7812de2d50949540d60f
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NR2F6 DOCK8 PFKFB4 SLC15A3

1.03e-041596840c2437da5443fc3aff66f8ef311f02aa434a1fb0
ToppCellCV-Healthy-3|CV / Virus stimulation, Condition and Cluster

ZSWIM8 STX1A KLHL21 TTLL4

1.08e-04161684fd4a79385ea967b9900dc76a3add813b894a3a28
ToppCellInfluenza_Severe-Neutrophil|Influenza_Severe / Disease group and Cell class

FAM170B ABCA1 LRFN1 DAAM2

1.08e-0416168498c95b1b85d5427415af2ca8fb14849e97f6e8b5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA1 TKT DENND5A SLC15A3

1.16e-0416468410741c7706a37b24aa08a300b27d60d6b8600167
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA1 TKT DENND5A SLC15A3

1.16e-041646847077683afee91828ad2b95e0f81c2b27aae0f831
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 P2RX1 LRP4 CPA1

1.21e-04166684b7f303203068b205f382788815df487a0ea148ed
ToppCellBronchial_Biopsy-Immune-Mast_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

P2RX1 SPTBN1 DAAM2 RCN3

1.27e-0416868445ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NR2F6 MDP1 ACACA RACGAP1

1.27e-041686844c402a1613fcf0a6e4d9b9d5551812940e91ff32
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DPEP1 TENM3 RCN3 AHNAK2

1.30e-04169684031465190cd3623a25ef2b868daab8d932c8ff08
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GRAMD1B TENM4 COL6A5 WDR90

1.33e-04170684ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NR2F6 SLC15A3 EZH2 SPDL1

1.36e-04171684845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCellwk_20-22-Mesenchymal-Chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TENM4 TENM3 DAAM2 RCN3

1.36e-04171684d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NR2F6 TKT PFKFB4 SLC15A3

1.39e-04172684584af6537685cb459bf0fc298e6f46872016c116
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

P2RX1 ATP11B JAZF1 HERC1

1.39e-04172684c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Basophil|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

P2RX1 ATP11B JAZF1 HERC1

1.39e-04172684953b05f776348cff784e79c93df65841939d880f
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P2RX1 LRP4 CPA1 SLC1A3

1.42e-04173684c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NR2F6 DOCK8 PFKFB4 SLC15A3

1.42e-0417368420f7dfe7d92a3dbec9da9a1f3185aa10cb8f0a3c
ToppCellsevere_influenza-Neutrophil|severe_influenza / disease group, cell group and cell class (v2)

FAM170B ABCA1 LRFN1 DAAM2

1.42e-04173684615e266419b9f06e964eff73cb466f05451ba0dd
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P2RX1 LRP4 CPA1 SLC1A3

1.42e-04173684f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TENM4 TENM3 RCN3 AHNAK2

1.42e-0417368430d67738633493d47f06ae452424382f069b6c0a
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRAMD1B TENM4 ACACA DAAM2

1.48e-041756841d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRAMD1B TENM4 ACACA DAAM2

1.48e-04175684427a7ee92fe16a90625946492062d37aa0f7235b
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

DYNC2H1 TTLL4 LRP3 SLC1A3

1.55e-0417768452c2ba74a8605260a2623e7d151286e504ac4d19
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM4 TENM3 SLC34A2 DENND5A

1.58e-04178684a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTLL4 RACGAP1 EZH2 SPDL1

1.65e-041806845e1680088065be14447d5d5465f91f7edd071a1e
ToppCellRA-11._Adipocyte|RA / Chamber and Cluster_Paper

TENM4 ACACA TENM3 SLC1A3

1.65e-04180684d48a3d27357f7d184132a6805950f93080146b59
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TENM4 TENM3 SLC15A3 DNAH11

1.69e-041816843aa81ac64d0cc9a74fbfa71e2176740548e7cd06
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TENM4 TENM3 SLC15A3 DNAH11

1.69e-04181684997ba1be2824b00d684f2163d0114656ed11fa53
ToppCellP28-Mesenchymal-mesenchymal_fibroblast|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DPEP1 LRP4 SLC1A3 RCN3

1.69e-04181684091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCell5'-Adult-Appendix-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TENM4 TENM3 SLC15A3 DNAH11

1.69e-04181684e6b7e8dd5c13cc10ba22f2f5a8c669486f934bdc
ToppCellClub-club-8|World / Class top

GRAMD1B DPEP1 EXOC3L4 SLC34A2

1.72e-041826848111d917e588008d947021460ddf8f1e7ae1337a
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR1 LRP4 SLC1A3 DNAH11

1.72e-041826848a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR1 LRP4 SLC1A3 DNAH11

1.72e-04182684a05e5978ef5f7fac7eeb2ba1c0103ea90d5e9136
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR1 LRP4 SLC1A3 DNAH11

1.72e-04182684831b5ce46b41efe01c4db6016c2f43148611373d
ToppCellP28-Mesenchymal|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DPEP1 LRP4 SLC1A3 RCN3

1.72e-0418268469f9d44694fe4f55a971ae0ac5dc3e7448ee78f3
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR1 LRP4 SLC1A3 DNAH11

1.72e-04182684e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCellLA-11._Adipocyte|World / Chamber and Cluster_Paper

TENM4 ACACA TENM3 SLC1A3

1.76e-04183684b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

TENM4 ACACA TENM3 SLC1A3

1.76e-041836843f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 TENM4 OBSCN DNAH11

1.80e-041846842cbed6462fea2622871bb7e49b0df3d984239281
ToppCelldroplet-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPEP1 LRP4 SLC1A3 RCN3

1.80e-0418468489ac32e374a4379e4a6c6ea7603b1378b77c147f
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DPEP1 LRP4 SLC1A3 RCN3

1.80e-04184684924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RACGAP1 NBEA EZH2 DNAH11

1.80e-04184684b998803180322a5ea2b567928dea531c26816c3c
ToppCellHippocampus-Macroglia|Hippocampus / BrainAtlas - Mouse McCarroll V32

DDR1 TKT EZH2 SLC1A3

1.80e-04184684a1d039ddf1e2a87b870f3ce6d139be56090349df
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR1 LRP4 DAAM2 SLC1A3

1.80e-04184684a2191dd5546efd357b23e625beb3c5820476f243
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 TENM4 OBSCN DNAH11

1.80e-04184684ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 TENM4 OBSCN DNAH11

1.80e-041846842b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPEP1 LRP4 SLC1A3 RCN3

1.80e-041846844df6027fa635996c1eddb920f88a5265772df1cd
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR1 LRP4 DAAM2 SLC1A3

1.83e-04185684b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TENM4 LRP4 DAAM2 AHNAK2

1.83e-041856846712512100ccef456d2e2bd201d0987986c92ac9
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Mega-Mast|bone_marrow / Manually curated celltypes from each tissue

ACACA EXOC3L4 DAAM2 WDR90

1.83e-04185684a62ebaff92f2ed27b27b32c27c89cfbe2cb35116
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACBD7 LRP4 DAAM2 SLC1A3

1.87e-0418668473cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCellMyeloid-B_(Activated_Macrophage)|World / shred on cell class and cell subclass (v4)

NR2F6 TKT SLC15A3 AHNAK2

1.87e-0418668433d731a7883d75e4e7db83b641cdb1e9a39938bf
ToppCell10x5'-Lung-Mast|Lung / Manually curated celltypes from each tissue

P2RX1 LRP4 NBEA AHNAK2

1.91e-04187684f8ac5ca5cbe9c6f3d8c0fffc20fe08ca1aea43c0
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR1 LRP4 SLC1A3 DNAH11

1.91e-04187684daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACBD7 LRP4 DAAM2 SLC1A3

1.91e-041876845d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCell10x5'-Lung-Mast-Mast_cells|Lung / Manually curated celltypes from each tissue

P2RX1 LRP4 NBEA AHNAK2

1.91e-04187684da275d2c774b3e6a8ed77f777dd0676ecf2ddd2c
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma|TCGA-Prostate / Sample_Type by Project: Shred V9

RHPN1 LRFN1 EZH2 VAV2

1.91e-04187684fa0452f3382c22c0391b241d06504fda3c6a19f0
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR1 LRP4 DAAM2 SLC1A3

1.91e-0418768497e520705491c8f52a32025311a9fa7b9176979a
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACBD7 LRP4 DAAM2 SLC1A3

1.91e-04187684401be371b32066db926de3415bb4ce9465749dc3
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACBD7 LRP4 DAAM2 SLC1A3

1.91e-041876845c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCelldroplet-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPEP1 LRP4 SLC1A3 RCN3

1.91e-0418768451f1c6bac3abae1d20aa8ac46642bcdbc02cb0a2
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DDR1 LRP4 SLC1A3 DNAH11

1.91e-041876845b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCellTCGA-Prostate-Primary_Tumor|TCGA-Prostate / Sample_Type by Project: Shred V9

RHPN1 LRFN1 EZH2 VAV2

1.91e-041876843e6a95c912dad5d61e10497ffaafd2b9027cd13a
ToppCellRA-11._Adipocyte|World / Chamber and Cluster_Paper

TENM4 ACACA TENM3 SLC1A3

1.95e-041886844dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCelldroplet-Lung-immune-endo-depleted|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPEP1 LRP4 SLC1A3 RCN3

1.99e-04189684c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCellfacs-Lung-18m-Mesenchymal|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DPEP1 LRP4 SLC1A3 RCN3

1.99e-04189684bdf8db938aa0863c4fed6fa99dcffd63c8c20c31
ToppCelldroplet-Lung-immune-endo-depleted-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPEP1 LRP4 SLC1A3 RCN3

1.99e-041896842a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DPEP1 LRP4 SLC1A3 RCN3

1.99e-0418968440cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK8 LRP4 DAAM2 SLC1A3

1.99e-0418968442ab4cc5fbf8580841f31889446fe4499df1a464
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPEP1 LRP4 SLC1A3 RCN3

1.99e-04189684324c81285c51f4f8bb1aef428b18fe2c549c2c11
ToppCellrenal_cortex_nuclei-Adult_normal_reference|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

GRAMD1B DPEP1 PDE4D THOC2

1.99e-04189684a48df46274d51e84ffb40264646de7346104efb9
ToppCelldroplet-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DPEP1 LRP4 SLC1A3 RCN3

1.99e-041896845a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DPEP1 LRP4 SLC1A3 RCN3

1.99e-04189684e76dc36a01d8ad7590b3acc4c46abfcb76857448
Diseasediffuse large B-cell lymphoma (is_marker_for)

BCL2L2 EZH2

1.45e-048682DOID:0050745 (is_marker_for)
DiseaseAL amyloidosis

GRAMD1B DNAH11

3.40e-0412682MONDO_0019438
DiseaseAutistic Disorder

STX1A HLA-A NBEA TSC2 SLC1A3

3.45e-04261685C0004352
Diseaseresponse to antipsychotic drug

TENM4 DYNC2H1 NBEA

3.65e-0460683GO_0097332
Diseasetransient cerebral ischemia (biomarker_via_orthology)

PDE4D ERCC6 BCL2L2 MADD

4.82e-04157684DOID:224 (biomarker_via_orthology)
Diseaseosteosarcoma (is_implicated_in)

DDR1 EZH2

6.15e-0416682DOID:3347 (is_implicated_in)
DiseaseChild Behaviour Checklist assessment

TENM4 TENM3

7.82e-0418682EFO_0005661
Diseaselung carcinoma

DDR1 PDE4D TENM4 DOCK8 COL6A5 DNAH11

8.57e-04482686EFO_0001071
DiseaseSchizophrenia

DDR1 ABCA1 STX1A PDE4D TENM4 HLA-A DAAM2 SLC1A3

9.43e-04883688C0036341
Diseaseprostate specific antigen measurement

HLA-A JAZF1 ATP9B DNAH11

9.46e-04188684EFO_0004624
DiseaseColorectal Carcinoma

DPEP1 ABCA1 ERCC6 ACACA BCAS2 OBSCN SMTN

1.15e-03702687C0009402
Diseaselobe attachment

FAT4 TTLL4 DAAM2 NBEA

1.35e-03207684EFO_0007667
DiseaseWeight Gain

SPTBN1 EZH2 DNAH11

1.71e-03102683C0043094
Diseasecolorectal adenocarcinoma (is_marker_for)

ERCC6 BCL2L2

1.77e-0327682DOID:0050861 (is_marker_for)
Diseaseresponse to quetiapine

PDE4D VCP

1.90e-0328682GO_0097335
DiseaseMental deterioration

TENM4 DNAH11

2.04e-0329682HP_0001268
DiseaseDrug-Induced Stevens Johnson Syndrome

HLA-A VCP

2.04e-0329682C1274933
DiseaseToxic Epidermal Necrolysis

HLA-A VCP

2.04e-0329682C0014518
DiseaseMycoplasma-Induced Stevens-Johnson Syndrome

HLA-A VCP

2.04e-0329682C3658301
DiseaseStevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum

HLA-A VCP

2.04e-0329682C3658302
DiseaseCiliopathies

DYNC2H1 TSC2 DNAH11

2.12e-03110683C4277690
Diseasechronic kidney disease

DPEP1 SPTBN1 COL6A5 MADD

2.14e-03235684EFO_0003884
Diseaseright ventricular ejection fraction measurement

ABCA1 OBSCN

2.18e-0330682EFO_0021816
DiseaseStevens-Johnson Syndrome

HLA-A VCP

2.18e-0330682C0038325

Protein segments in the cluster

PeptideGeneStartEntry
RTFEQDPTAFARRAM

EXOC3L4

166

Q17RC7
QEQMFAFRSRARSTD

CPA1

101

P15085
EFEFDRLRAFQAMQV

DDR1

271

Q08345
FDRESLMRRRGTAVF

FAT4

1161

Q6V0I7
QAMADALERFGENRF

ABCA1

1826

O95477
MAAQVAAREARDFRE

DNAH11

1

Q96DT5
MVSFRTFEDFVRIFD

ACACA

1236

Q13085
MRAAGDEFETRFRRT

BCL2L2

46

Q92843
FFRMFDRDTRRDVTL

PPP2R2D

371

Q66LE6
SPFQRDFMEQRRFSD

GRAMD1B

396

Q3KR37
RFRVADQDGDSMATR

RCN3

171

Q96D15
AAERAVAFMDQVRAF

NR2F6

271

P10588
VSAAMRRDRFETIFS

ERCC6

681

P0DP91
QAFSEARQDLEAMRR

DAAM2

966

Q86T65
DVATRVAMVRFFNSA

MADD

486

Q8WXG6
SQMIFFDDERRNIVD

MDP1

116

Q86V88
FIAAVRRRDFANMTS

LRFN1

76

Q9P244
AVTMTREAIDEFRRF

ATP9B

191

O43861
LEEFSNEERVLFMRF

HERC1

4761

Q15751
INRFMTDAARREQES

JAZF1

61

Q86VZ6
MADRFSRFNEDRDFQ

GPATCH8

1

Q9UKJ3
RFRRADEVKSMFSSN

EZH2

31

Q15910
DRIMEEFFRQGDRER

PDE4D

636

Q08499
NRDSDEATEDFMRRI

PFKFB4

181

Q16877
RAFETQMTRLEAEFV

LRP3

531

O75074
FFEEMLERRRAQGQA

FAM170B

236

A6NMN3
TEARQAVTRFQEMFA

OBSCN

5066

Q5VST9
TRFNRVDEDFRSIMT

DYNC2H1

1366

Q8NCM8
FRAMFAGQLRESRAE

KLHL21

61

Q9UJP4
SFRRTRFSDRFMDDI

DOCK8

1006

Q8NF50
MDATALERDAVQFAR

CAPN7

1

Q9Y6W3
ALREFFDSLNEAIMR

SLC1A3

266

P43003
RDVGNAMRFVTRNVF

COL6A5

1841

A8TX70
ENEMFSIRDSAHRRF

IL24

156

Q13007
MALQADFDRAAEDVR

ACBD7

1

Q8N6N7
IREVFANRFTQMFAD

DENND5A

516

Q6IQ26
QFVRFDSDAASQRME

HLA-A

56

P04439
ADFFRDEAERIMRDS

DPEP1

16

P16444
QVMDLGRDATRRFFN

SLC15A3

186

Q8IY34
ERRMRAAFTAFEEAQ

CCDC124

166

Q96CT7
MARRFQEELAAFLFE

P2RX1

1

P51575
DFVRINRMALESEFV

NBEA

2476

Q8NFP9
SLFAEVEDRRAAMER

SPDL1

256

Q96EA4
ALRSFQMARVIFNRD

SHLD1

141

Q8IYI0
FETDIMRNEFERLAA

BCAS2

61

O75934
FRLNRAFMEAAEITD

RACGAP1

436

Q9H0H5
TEGARRAMEAFQRAA

RHPN1

236

Q8TCX5
EHVTMLQERFREFAR

SPTBN1

1731

Q01082
GFVAFMNRRDAERAL

U2SURP

321

O15042
RTFFRMSRPEAVQEA

AHNAK2

96

Q8IVF2
EFDSDRRRMSVIVQA

ATP11B

571

Q9Y2G3
LMQVGDRSEFRRAFA

SLC34A2

201

O95436
DVQAFRVTFFDETRM

WDR90

506

Q96KV7
AESFEDLRRDVFNMF

THOC2

421

Q8NI27
AFFTRAFDQIRMAAI

TKT

391

P29401
FEEAMRFARRSVSDN

VCP

736

P55072
AVTVDRDRFMDEFFE

STX1A

21

Q16623
RRERAFDANTMTSAE

MID1

101

O15344
RQIFRFTEEGMVNAR

TENM4

2066

Q6N022
VNGRTRRFADVEMQF

TENM3

2586

Q9P273
ADEFQRGDQLFRMRA

ZSWIM8

131

A7E2V4
AEAAMTAADRAIQRF

USP30

6

Q70CQ3
AVARYNFAARDMREL

VAV2

821

P52735
FYVTAFDRDRAMQRL

TRIP12

1551

Q14669
VEMEDEFSRRGQFER

TTLL4

1011

Q14679
RRQNFEVAFSSAEML

SMTN

856

P53814
QALMERFFRSESRGA

TSC2

446

P49815
FARRMDIRRISFDTE

LRP4

746

O75096