Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3K9 demethylase activity

JMJD1C KDM4D KDM4A KDM4B

6.42e-07141034GO:0032454
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

TRPC4 TRPC5 ITPR3 PLCD1

6.42e-07141034GO:0070679
GeneOntologyMolecularFunctionhistone H3K9me2/H3K9me3 demethylase activity

KDM4D KDM4A KDM4B

2.64e-0661033GO:0140684
GeneOntologyMolecularFunctiondioxygenase activity

P4HA2 JMJD1C KDM4D P4HA1 KDM4A KDM4B

1.17e-05981036GO:0051213
GeneOntologyMolecularFunctionhistone H3 demethylase activity

JMJD1C KDM4D KDM4A KDM4B

1.24e-05281034GO:0141052
GeneOntologyMolecularFunctionhistone demethylase activity

JMJD1C KDM4D KDM4A KDM4B

1.89e-05311034GO:0032452
GeneOntologyMolecularFunctionpyrimidine nucleotide binding

POLA1 HSP90AA1 HSP90AB1

2.13e-05111033GO:0019103
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

P4HA2 KDM4D P4HA1 KDM4A KDM4B

2.14e-05651035GO:0016706
GeneOntologyMolecularFunctionprotein demethylase activity

JMJD1C KDM4D KDM4A KDM4B

2.15e-05321034GO:0140457
GeneOntologyMolecularFunctionCTP binding

HSP90AA1 HSP90AB1

2.64e-0521032GO:0002135
GeneOntologyMolecularFunctiondisordered domain specific binding

HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1

4.78e-05391034GO:0097718
GeneOntologyMolecularFunctionATP-dependent protein folding chaperone

HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1

5.29e-05401034GO:0140662
GeneOntologyMolecularFunctiondemethylase activity

JMJD1C KDM4D KDM4A KDM4B

7.73e-05441034GO:0032451
GeneOntologyMolecularFunctionsulfonylurea receptor binding

HSP90AA1 HSP90AB1

7.88e-0531032GO:0017098
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA4 ABCA13 ABCB5 ABCG1

1.18e-04491034GO:0140359
GeneOntologyMolecularFunctionUTP binding

HSP90AA1 HSP90AB1

1.57e-0441032GO:0002134
GeneOntologyMolecularFunctionalcohol binding

TRPC4 TRPC5 ITPR3 ABCG1 PLCD1

1.86e-041021035GO:0043178
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ATP6V0C ABCA4 ABCA13 ABCB5 ABCG1

2.53e-041091035GO:0042626
GeneOntologyMolecularFunctionprocollagen-proline 4-dioxygenase activity

P4HA2 P4HA1

2.61e-0451032GO:0004656
GeneOntologyMolecularFunctionpyrimidine ribonucleotide binding

HSP90AA1 HSP90AB1

2.61e-0451032GO:0032557
GeneOntologyMolecularFunctiondATP binding

HSP90AA1 HSP90AB1

2.61e-0451032GO:0032564
GeneOntologyMolecularFunctionadenyl deoxyribonucleotide binding

HSP90AA1 HSP90AB1

3.90e-0461032GO:0032558
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA4 ABCA13 ABCB5 UPF1 ABCG1 HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1

4.63e-044411039GO:0016887
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

ABCA4 AQP3 ABCG1 SLC18A1

4.71e-04701034GO:1901618
GeneOntologyMolecularFunctionpurine deoxyribonucleotide binding

HSP90AA1 HSP90AB1

5.44e-0471032GO:0032554
GeneOntologyMolecularFunctionprotein folding chaperone

HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1

5.53e-04731034GO:0044183
GeneOntologyMolecularFunctionTPR domain binding

HSP90AA1 HSP90AB1

7.23e-0481032GO:0030911
GeneOntologyMolecularFunctionpeptidyl-proline 4-dioxygenase activity

P4HA2 P4HA1

7.23e-0481032GO:0031545
GeneOntologyMolecularFunctionprocollagen-proline dioxygenase activity

P4HA2 P4HA1

7.23e-0481032GO:0019798
GeneOntologyMolecularFunctiondeoxyribonucleotide binding

HSP90AA1 HSP90AB1

9.26e-0491032GO:0032552
GeneOntologyMolecularFunctionnitric-oxide synthase regulator activity

HSP90AA1 HSP90AB1

1.15e-03101032GO:0030235
GeneOntologyMolecularFunctionATP-dependent activity

ATP6V0C ABCA4 ABCA13 ABCB5 UPF1 ABCG1 HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1

1.27e-0361410310GO:0140657
GeneOntologyMolecularFunctionhistone H3K36 demethylase activity

KDM4A KDM4B

1.41e-03111032GO:0051864
GeneOntologyMolecularFunctionstore-operated calcium channel activity

TRPC4 TRPC5

1.68e-03121032GO:0015279
GeneOntologyMolecularFunctionpeptidyl-proline dioxygenase activity

P4HA2 P4HA1

1.68e-03121032GO:0031543
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL3A1 COL7A1 COL12A1

1.72e-03461033GO:0030020
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ATP6V0C ABCA4 ABCA13 ABCB5 ABCG1

2.30e-031781035GO:0015399
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCA4 CLPTM1L ABCG1

2.32e-03511033GO:0140303
GeneOntologyMolecularFunctiontransporter activity

ATP6V0C ABCA4 ABCA13 ABCB5 TRPC4 TRPC5 AQP3 SLC45A4 ITPR3 CLPTM1L ABCG1 SLC18A1 SLC16A14 NIPAL2 TRPM8

2.48e-03128910315GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

ATP6V0C ABCA4 ABCA13 ABCB5 TRPC4 TRPC5 AQP3 SLC45A4 ITPR3 ABCG1 SLC18A1 SLC16A14 NIPAL2 TRPM8

2.93e-03118010314GO:0022857
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1B LRP1

3.02e-03161032GO:0005041
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ATP6V0C ABCA4 ABCA13 ABCB5 SLC45A4 ABCG1 SLC18A1 SLC16A14

3.28e-034771038GO:0022804
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

P4HA2 KDM4D P4HA1 KDM4A KDM4B

3.34e-031941035GO:0016705
GeneOntologyMolecularFunctionunfolded protein binding

HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1

4.13e-031261034GO:0051082
GeneOntologyMolecularFunctioncalcium channel activity

TRPC4 TRPC5 ITPR3 TRPM8

4.49e-031291034GO:0005262
GeneOntologyMolecularFunctionL-ascorbic acid binding

P4HA2 P4HA1

4.71e-03201032GO:0031418
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1B LRP1

5.19e-03211032GO:0030228
GeneOntologyCellularComponentanchoring collagen complex

COL7A1 COL12A1

6.91e-0531012GO:0030934
GeneOntologyCellularComponentprocollagen-proline 4-dioxygenase complex

P4HA2 P4HA1

6.91e-0531012GO:0016222
GeneOntologyCellularComponentbasolateral plasma membrane

TRPC4 VSIG1 ITGA6 AQP3 ADCY8 LRP1 HSP90AA1 HSP90AB1

1.63e-043201018GO:0016323
GeneOntologyCellularComponentbasal plasma membrane

TRPC4 VSIG1 ITGA6 AQP3 ADCY8 LRP1 HSP90AA1 HSP90AB1

3.22e-043541018GO:0009925
GeneOntologyCellularComponentstereocilium membrane

RIPOR2 ADGRV1

3.42e-0461012GO:0060171
GeneOntologyCellularComponentpericentric heterochromatin

KDM4D KDM4A KDM4B

4.90e-04321013GO:0005721
GeneOntologyCellularComponentbasal part of cell

TRPC4 VSIG1 ITGA6 AQP3 ADCY8 LRP1 HSP90AA1 HSP90AB1

4.97e-043781018GO:0045178
DomainJmjC

JMJD1C KDM4D KDM4A KDM4B

7.88e-06241014PF02373
DomainJmjN

KDM4D KDM4A KDM4B

1.79e-05101013SM00545
DomainJmjN

KDM4D KDM4A KDM4B

1.79e-05101013PF02375
DomainJMJN

KDM4D KDM4A KDM4B

1.79e-05101013PS51183
DomainJmjN

KDM4D KDM4A KDM4B

1.79e-05101013IPR003349
DomainJMJC

JMJD1C KDM4D KDM4A KDM4B

2.58e-05321014PS51184
DomainJmjC_dom

JMJD1C KDM4D KDM4A KDM4B

2.58e-05321014IPR003347
DomainDUF3697_Uba2

UBAP2 UBAP2L

2.90e-0521012IPR022166
DomainDUF5050

LRP1B LRP1

2.90e-0521012IPR032485
DomainDUF3697

UBAP2 UBAP2L

2.90e-0521012PF12478
DomainDUF5050

LRP1B LRP1

2.90e-0521012PF16472
DomainJmjC

JMJD1C KDM4D KDM4A KDM4B

2.92e-05331014SM00558
DomainP4Ha_N

P4HA2 P4HA1

8.66e-0531012PF08336
DomainHeat_shock_protein_90_CS

HSP90AA1 HSP90AB1

8.66e-0531012IPR019805
DomainPro_4_hyd_alph_N

P4HA2 P4HA1

8.66e-0531012IPR013547
DomainABC_tran

ABCA4 ABCA13 ABCB5 ABCG1

1.31e-04481014PF00005
DomainABC_TRANSPORTER_2

ABCA4 ABCA13 ABCB5 ABCG1

1.31e-04481014PS50893
DomainABC_TRANSPORTER_1

ABCA4 ABCA13 ABCB5 ABCG1

1.42e-04491014PS00211
DomainABC_transporter-like

ABCA4 ABCA13 ABCB5 ABCG1

1.53e-04501014IPR003439
DomainHsp90_fam

HSP90AA1 HSP90AB1

1.73e-0441012IPR001404
DomainHsp90_N

HSP90AA1 HSP90AB1

1.73e-0441012IPR020575
DomainHSP90

HSP90AA1 HSP90AB1

1.73e-0441012PF00183
DomainHSP90

HSP90AA1 HSP90AB1

1.73e-0441012PS00298
DomainTRP_2

TRPC4 TRPC5

4.28e-0461012PF08344
DomainTRP_dom

TRPC4 TRPC5

4.28e-0461012IPR013555
DomainTRPC_channel

TRPC4 TRPC5

5.97e-0471012IPR002153
Domain-

LRP1B RGN LRP1

1.22e-033910132.120.10.30
DomainABC_transporter_CS

ABCA4 ABCB5 ABCG1

1.51e-03421013IPR017871
DomainTRP_channel

TRPC4 TRPC5

1.54e-03111012IPR004729
Domain2OG-FeII_Oxy_3

P4HA2 P4HA1

1.54e-03111012PF13640
DomainABC_A

ABCA4 ABCA13

1.84e-03121012IPR026082
Domain6-blade_b-propeller_TolB-like

LRP1B RGN LRP1

1.97e-03461013IPR011042
Domain-

LRP1B LRP1 ALK

1.97e-034610134.10.400.10
DomainLDLRA_1

LRP1B LRP1 ALK

2.23e-03481013PS01209
DomainLDrepeatLR_classA_rpt

LRP1B LRP1 ALK

2.36e-03491013IPR002172
DomainLDLa

LRP1B LRP1 ALK

2.36e-03491013SM00192
DomainLDLRA_2

LRP1B LRP1 ALK

2.36e-03491013PS50068
DomainLdl_recept_b

LRP1B LRP1

2.53e-03141012PF00058
DomainLDLRB

LRP1B LRP1

2.53e-03141012PS51120
DomainLY

LRP1B LRP1

2.90e-03151012SM00135
DomainLDLR_classB_rpt

LRP1B LRP1

2.90e-03151012IPR000033
DomainP4Hc

P4HA2 P4HA1

3.31e-03161012SM00702
DomainSEC7

PSD3 ARFGEF3

3.31e-03161012PS50190
DomainSec7

PSD3 ARFGEF3

3.31e-03161012SM00222
DomainSec7_dom

PSD3 ARFGEF3

3.31e-03161012IPR000904
DomainPro_4_hyd_alph

P4HA2 P4HA1

3.31e-03161012IPR006620
DomainIon_trans_dom

TRPC4 TRPC5 ITPR3 TRPM8

3.41e-031141014IPR005821
DomainIon_trans

TRPC4 TRPC5 ITPR3 TRPM8

3.41e-031141014PF00520
DomainHATPase_c

HSP90AA1 HSP90AB1

4.19e-03181012SM00387
DomainHATPase_c

HSP90AA1 HSP90AB1

4.66e-03191012PF02518
Domain2OG-FeII_Oxy

P4HA2 P4HA1

4.66e-03191012PF03171
Domain-

HSP90AA1 HSP90AB1

5.16e-032010123.30.565.10
PathwayREACTOME_COLLAGEN_FORMATION

COL3A1 P4HA2 COL7A1 COL12A1 ITGA6 P4HA1

1.79e-0590866M631
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL3A1 P4HA2 COL7A1 COL12A1 P4HA1

3.42e-0561865MM14637
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL3A1 P4HA2 COL7A1 COL12A1 P4HA1

5.39e-0567865M26999
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PAK3 HSP90AA1 HSP90AB1

7.60e-0514863MM15029
PathwayREACTOME_COLLAGEN_FORMATION

COL3A1 P4HA2 COL7A1 COL12A1 P4HA1

9.88e-0576865MM14573
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PAK3 HSP90AA1 HSP90AB1

1.16e-0416863M16498
PathwayKEGG_ABC_TRANSPORTERS

ABCA4 ABCA13 ABCB5 ABCG1

1.46e-0444864M11911
Pubmed

Synergistic role of HSP90α and HSP90β to promote myofibroblast persistence in lung fibrosis.

LRP1 HSP90AA1 HSP90AB1

2.60e-083104329386344
Pubmed

Mapping of the gene family for human heat-shock protein 90 alpha to chromosomes 1, 4, 11, and 14.

HSP90AA1 HSP90AA4P HSP90AA2P

1.04e-07410431740332
Pubmed

Heat shock protein 90 (Hsp90) selectively regulates the stability of KDM4B/JMJD2B histone demethylase.

KDM4B HSP90AA1 HSP90AA2P

1.04e-074104323589305
Pubmed

The HSP90 family of genes in the human genome: insights into their divergence and evolution.

HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1

1.34e-0716104416269234
Pubmed

Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family.

KDM4D KDM4A KDM4B

2.59e-075104321914792
Pubmed

Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells.

KDM4D KDM4A KDM4B

2.59e-075104316738407
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

HIVEP2 MINK1 ST3GAL3 ADGRV1 STK32C JMJD1C TATDN3 ARFGEF3 MALT1 ABCG1 PPP4C UBAP2L SLC16A14 LRP1 PAK3 STYXL1 XYLB KDM4B

4.23e-0714891041828611215
Pubmed

Identification and characterization of JMJD2 family genes in silico.

KDM4D KDM4A KDM4B

5.16e-076104315138608
Pubmed

Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.

P4HA2 ATP6V0C RANBP2 LAMA4 ITGA6 CUL9 UPF1 ATP5MK P4HA1 LRP1 ALDH2 HSP90AA1 HSP90AB1

1.80e-068591041331536960
Pubmed

Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels.

TRPC4 TRPC5 ITPR3

2.15e-069104311290752
Pubmed

Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins.

KDM4D KDM4A KDM4B

4.21e-0611104319144645
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

MTA2 RANBP2 POLA1 UPF1 P4HA1 UBAP2L HSP90AA1 HSP90AB1

7.37e-06332104832786267
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1B LRP1

8.86e-062104215963947
Pubmed

Collagen prolyl 4-hydroxylase isoenzymes I and II have sequence specificity towards different X-Pro-Gly triplets.

P4HA2 P4HA1

8.86e-062104238081527
Pubmed

Hsp90 is cleaved by reactive oxygen species at a highly conserved N-terminal amino acid motif.

HSP90AA1 HSP90AB1

8.86e-062104222848402
Pubmed

A mouse tumor-specific transplantation antigen is a heat shock-related protein.

HSP90AA1 HSP90AB1

8.86e-06210423458168
Pubmed

Mechanism of dimer formation of the 90-kDa heat-shock protein.

HSP90AA1 HSP90AB1

8.86e-06210427588731
Pubmed

Reader domain specificity and lysine demethylase-4 family function.

KDM4A KDM4B

8.86e-062104227841353
Pubmed

Targeting HIF-activated collagen prolyl 4-hydroxylase expression disrupts collagen deposition and blocks primary and metastatic uveal melanoma growth.

P4HA2 P4HA1

8.86e-062104234218269
Pubmed

HSP90 expression and early recurrence in gastroenteropancreatic neuroendocrine tumors: Potential for a novel therapeutic target.

HSP90AA1 HSP90AB1

8.86e-062104233080545
Pubmed

Circulating Hsp90 Isoform Levels in Overweight and Obese Children and the Relation to Nonalcoholic Fatty Liver Disease: Results from a Cross-Sectional Study.

HSP90AA2P HSP90AB1

8.86e-062104231885746
Pubmed

Heat shock protein 90 facilitates SARS-CoV-2 structural protein-mediated virion assembly and promotes virus-induced pyroptosis.

HSP90AA1 HSP90AB1

8.86e-062104237011862
Pubmed

Cell surface heparan sulfate proteoglycans are involved in the binding of Hsp90α and Hsp90β to the cell plasma membrane.

HSP90AA2P HSP90AB1

8.86e-062104226651243
Pubmed

RANBP2-ALK fusion combined with monosomy 7 in acute myelomonocytic leukemia.

RANBP2 ALK

8.86e-062104224613277
Pubmed

Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis.

LAMA4 ITGA6

8.86e-062104225218639
Pubmed

Proliferation, migration, and resistance to oxidative and thermal stresses of HT1080 cells with knocked out genes encoding Hsp90α and Hsp90β.

HSP90AA1 HSP90AB1

8.86e-062104237406487
Pubmed

Expression and therapeutic relevance of heat-shock protein 90 in pancreatic endocrine tumors.

HSP90AA1 HSP90AB1

8.86e-062104222194440
Pubmed

Circadian expression of 86- and 84-kDa heat shock proteins in the mouse suprachiasmatic nucleus.

HSP90AA1 HSP90AB1

8.86e-062104218480550
Pubmed

Cloning of the human prolyl 4-hydroxylase alpha subunit isoform alpha(II) and characterization of the type II enzyme tetramer. The alpha(I) and alpha(II) subunits do not form a mixed alpha(I)alpha(II)beta2 tetramer.

P4HA2 P4HA1

8.86e-06210429211872
Pubmed

Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.

TRPC4 TRPC5

8.86e-062104222457348
Pubmed

Conserved gating elements in TRPC4 and TRPC5 channels.

TRPC4 TRPC5

8.86e-062104223677990
Pubmed

Mitochondrial heat shock protein-90 modulates vascular smooth muscle cell survival and the vascular injury response in vivo.

HSP90AA1 HSP90AB1

8.86e-062104222841823
Pubmed

Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells.

TRPC4 TRPC5

8.86e-062104232033274
Pubmed

Substitution of only two residues of human Hsp90alpha causes impeded dimerization of Hsp90beta.

HSP90AA1 HSP90AB1

8.86e-062104218347946
Pubmed

The first ankyrin-like repeat is the minimum indispensable key structure for functional assembly of homo- and heteromeric TRPC4/TRPC5 channels.

TRPC4 TRPC5

8.86e-062104217624425
Pubmed

UBAP2/UBAP2L regulate UV-induced ubiquitylation of RNA polymerase II and are the human orthologues of yeast Def1.

UBAP2 UBAP2L

8.86e-062104235633597
Pubmed

lingerer, a Drosophila gene involved in initiation and termination of copulation, encodes a set of novel cytoplasmic proteins.

UBAP2 UBAP2L

8.86e-062104212524348
Pubmed

Heat shock protein 90 overexpression independently predicts inferior disease-free survival with differential expression of the alpha and beta isoforms in gastrointestinal stromal tumors.

HSP90AA1 HSP90AB1

8.86e-062104219047110
Pubmed

Participation of the lipoprotein receptor LRP1 in hypoxia-HSP90alpha autocrine signaling to promote keratinocyte migration.

LRP1 HSP90AA2P

8.86e-062104219383717
Pubmed

Identification of RANBP2-ALK fusion in ALK positive diffuse large B-cell lymphoma.

RANBP2 ALK

8.86e-062104224470379
Pubmed

Heat shock protein HSP86 expression during mouse embryo development, especially in the germ-line.

HSP90AA1 HSP90AB1

8.86e-062104212136260
Pubmed

Expression of hsp90 and cyclin D1 in human breast cancer.

HSP90AA1 HSP90AB1

8.86e-062104210376793
Pubmed

Downregulation of TRPC4 and TRPC5 Inhibits Smooth Muscle Cell Proliferation without Affecting Endothelial Cell Proliferation.

TRPC4 TRPC5

8.86e-062104234899056
Pubmed

Corticolimbic expression of TRPC4 and TRPC5 channels in the rodent brain.

TRPC4 TRPC5

8.86e-062104217593972
Pubmed

Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target.

HSP90AA1 HSP90AB1

8.86e-062104233179566
Pubmed

Regulation of embryonic stem cell pluripotency by heat shock protein 90.

HSP90AA1 HSP90AB1

8.86e-062104222696450
Pubmed

Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects.

HSP90AA1 HSP90AB1

8.86e-062104222895790
Pubmed

The emerging role of lysine demethylases in DNA damage response: dissecting the recruitment mode of KDM4D/JMJD2D to DNA damage sites.

JMJD1C KDM4D

8.86e-062104225714495
Pubmed

Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice.

TRPC4 TRPC5

8.86e-062104226317356
Pubmed

Expression of Hsp90 chaperone [corrected] proteins in human tumor tissue.

HSP90AA1 HSP90AB1

8.86e-062104219576239
Pubmed

Proline hydroxylation in collagen supports integrin binding by two distinct mechanisms.

P4HA2 P4HA1

8.86e-062104229615493
Pubmed

A novel capacitative calcium entry channel expressed in excitable cells.

TRPC4 TRPC5

8.86e-06210429687496
Pubmed

Murine 86- and 84-kDa heat shock proteins, cDNA sequences, chromosome assignments, and evolutionary origins.

HSP90AA1 HSP90AB1

8.86e-06210422925609
Pubmed

Intracellular acidification facilitates receptor-operated TRPC4 activation through PLCδ1 in a Ca2+ -dependent manner.

TRPC4 PLCD1

8.86e-062104232338378
Pubmed

Heat-shock proteins, Hsp84 and Hsp86, of mice and men: two related genes encode formerly identified tumour-specific transplantation antigens.

HSP90AA1 HSP90AB1

8.86e-06210422469626
Pubmed

Cloning and analysis of a human 86-kDa heat-shock-protein-encoding gene.

HSP90AA1 HSP90AA2P

8.86e-06210422591742
Pubmed

Strong KDM4B and KDM4D Expression Associates with Radioresistance and Aggressive Phenotype in Classical Hodgkin Lymphoma.

KDM4D KDM4B

8.86e-062104227630312
Pubmed

Translational reprogramming in response to accumulating stressors ensures critical threshold levels of Hsp90 for mammalian life.

HSP90AA1 HSP90AB1

8.86e-062104236270993
Pubmed

Hsp90 regulation of fibroblast activation in pulmonary fibrosis.

HSP90AA1 HSP90AB1

8.86e-062104228239659
Pubmed

Despite their structural similarities, the cytosolic isoforms of human Hsp90 show different behaviour in thermal unfolding due to their conformation: An FTIR study.

HSP90AA1 HSP90AB1

8.86e-062104237028636
Pubmed

Critical roles of Gi/o proteins and phospholipase C-δ1 in the activation of receptor-operated TRPC4 channels.

TRPC4 PLCD1

8.86e-062104226755577
Pubmed

Conserved conformational changes in the ATPase cycle of human Hsp90.

HSP90AA1 HSP90AB1

8.86e-062104218400751
Pubmed

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A.

TRPC4 TRPC5

8.86e-062104230038709
Pubmed

Inhibition of RPE cell sterile inflammatory responses and endotoxin-induced uveitis by a cell-impermeable HSP90 inhibitor.

HSP90AA1 HSP90AB1

8.86e-062104222019372
Pubmed

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.

KDM4D KDM4A KDM4B

9.23e-0614104316603238
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

ADGRV1 LRP1B ITPR3 LRP1 ALK

1.37e-05101104523382219
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

COL3A1 MTA2 P4HA2 COL7A1 COL12A1 LAMA4 ITGA6 EXT1 LRP1B P3H4 KLHL11 CLPTM1L P4HA1 LRP1

1.40e-0512011041435696571
Pubmed

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.

JMJD1C KDM4D KDM4A KDM4B

1.44e-0549104434368113
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

RANBP2 MINK1 PSD3 ITGA6 ITPR3 PPP4C P4HA1 CD2BP2 STYXL1 TNS1 HSP90AA1 PHLPP2 HSP90AB1

1.54e-0510491041327880917
Pubmed

A human MAP kinase interactome.

RANBP2 RIPOR2 HIVEP2 LAMA4 STK32C PAK3 TNS1 HSP90AA1 HSP90AB1

1.60e-05486104920936779
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

KLHL10 MINK1 TFDP3 STK32C FER ALK HSP90AA1 HSP90AB1

1.68e-05372104822939624
Pubmed

Analysis of the mTOR Interactome using SILAC technology revealed NICE-4 as a novel regulator of mTORC1 activity.

UBAP2L HSP90AA1 HSP90AB1

2.05e-0518104334171383
Pubmed

Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory.

TRPC4 TRPC5

2.65e-053104228790178
Pubmed

KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1.

KDM4A KDM4B

2.65e-053104226397136
Pubmed

The tumor suppressor activity of DLC1 requires the interaction of its START domain with Phosphatidylserine, PLCD1, and Caveolin-1.

DLC1 PLCD1

2.65e-053104234727930
Pubmed

Mutations that increase both Hsp90 ATPase activity in vitro and Hsp90 drug resistance in vivo.

HSP90AA1 HSP90AB1

2.65e-053104220226818
Pubmed

Differential PI(4,5)P2 sensitivities of TRPC4, C5 homomeric and TRPC1/4, C1/5 heteromeric channels.

TRPC4 TRPC5

2.65e-053104230755645
Pubmed

Regulation of type II collagen synthesis during osteoarthritis by prolyl-4-hydroxylases: possible influence of low oxygen levels.

P4HA2 P4HA1

2.65e-053104216877351
Pubmed

Modulation of Akt kinase activity by binding to Hsp90.

HSP90AA1 HSP90AB1

2.65e-053104210995457
Pubmed

The regulatory mechanism of extracellular Hsp90{alpha} on matrix metalloproteinase-2 processing and tumor angiogenesis.

HSP90AA1 HSP90AA2P

2.65e-053104220937816
Pubmed

Regulation of cytosolic phospholipase A2alpha by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages.

HSP90AA1 HSP90AB1

2.65e-053104218550790
Pubmed

Mammalian heat shock factor 1 is essential for oocyte meiosis and directly regulates Hsp90alpha expression.

HSP90AA1 HSP90AB1

2.65e-053104219158073
Pubmed

No association between COL3A1, COL6A1 or COL12A1 gene variants and range of motion.

COL3A1 COL12A1

2.65e-053104223013106
Pubmed

Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells.

HSP90AA1 HSP90AB1

2.65e-053104222849407
Pubmed

Genetics of migraine in the age of genome-wide association studies.

LRP1 TRPM8

2.65e-053104222072275
Pubmed

Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6.

HSP90AA1 HSP90AB1

2.65e-053104219996089
Pubmed

Receptor ligand-triggered resistance to alectinib and its circumvention by Hsp90 inhibition in EML4-ALK lung cancer cells.

ALK HSP90AA1

2.65e-053104224952482
Pubmed

Comparative integromics on JMJD2A, JMJD2B and JMJD2C: preferential expression of JMJD2C in undifferentiated ES cells.

KDM4A KDM4B

2.65e-053104217611647
Pubmed

The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice.

KDM4D KDM4A

2.65e-053104221555854
Pubmed

Hsp90 regulates the activity of wild type p53 under physiological and elevated temperatures.

HSP90AA1 HSP90AB1

2.65e-053104215358771
Pubmed

Tensin1 requires protein phosphatase-1alpha in addition to RhoGAP DLC-1 to control cell polarization, migration, and invasion.

DLC1 TNS1

2.65e-053104219826001
Pubmed

ABCG1 Attenuates Oxidative Stress Induced by H2O2 through the Inhibition of NADPH Oxidase and the Upregulation of Nrf2-Mediated Antioxidant Defense in Endothelial Cells.

ABCG1 NOX1

2.65e-053104233344146
Pubmed

Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit.

P4HA2 P4HA1

2.65e-05310427753822
Pubmed

Transient Receptor Potential C 1/4/5 Is a Determinant of MTI-101 Induced Calcium Influx and Cell Death in Multiple Myeloma.

TRPC4 TRPC5

2.65e-053104234199280
Pubmed

Molecular recognition via coupled folding and binding in a TPR domain.

HSP90AA1 HSP90AB1

2.65e-053104215713458
Pubmed

Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D.

KDM4D KDM4A

2.65e-053104217555712
Pubmed

Two human 90-kDa heat shock proteins are phosphorylated in vivo at conserved serines that are phosphorylated in vitro by casein kinase II.

HSP90AA1 HSP90AB1

2.65e-05310422492519
Pubmed

Conformational activation of a basic helix-loop-helix protein (MyoD1) by the C-terminal region of murine HSP90 (HSP84).

HSP90AA1 HSP90AB1

2.65e-05310421406681
Pubmed

Mammalian CHORD-containing protein 1 is a novel heat shock protein 90-interacting protein.

HSP90AA1 HSP90AB1

2.65e-053104215642353
Pubmed

Tensin1 positively regulates RhoA activity through its interaction with DLC1.

DLC1 TNS1

2.65e-053104226427649
InteractionSRMS interactions

P4HA2 PLCD1 HSP90AA1 HSP90AA4P HSP90AB1

1.64e-06401015int:SRMS
InteractionLIMK2 interactions

STK32C ATP5MK SLC18A1 HSP90AA1 HSP90AA4P HSP90AB1

4.04e-06841016int:LIMK2
InteractionSBK2 interactions

TMPRSS11E HSP90AA1 HSP90AB1

4.21e-0671013int:SBK2
InteractionSTK32C interactions

RANBP2 STK32C ATP5MK HSP90AA1 HSP90AA4P HSP90AB1

4.96e-06871016int:STK32C
InteractionCDKL5 interactions

RANBP2 UBAP2 MINK1 PSD3 UBAP2L HSP90AB1

2.24e-051131016int:CDKL5
Cytoband3p22-p21.3

PLCD1 XYLB

3.04e-05410423p22-p21.3
Cytoband17q21.2

KLHL10 P3H4 KLHL11

5.54e-0470104317q21.2
GeneFamilyPHD finger proteins|Lysine demethylases

JMJD1C KDM4D KDM4A KDM4B

2.19e-0624714485
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

TRPC5 ITPR3 ARFGEF3 CD2BP2 FER TNS1

7.74e-05181716694
GeneFamilyHeat shock 90kDa proteins

HSP90AA1 HSP90AB1

1.51e-045712586
GeneFamilyTransient receptor potential cation channels

TRPC4 TRPC5 TRPM8

1.77e-0428713249
GeneFamilyCollagens

COL3A1 COL7A1 COL12A1

7.80e-0446713490
GeneFamilyLow density lipoprotein receptors

LRP1B LRP1

1.15e-0313712634
GeneFamilyATP binding cassette subfamily A

ABCA4 ABCA13

1.34e-0314712805
CoexpressionLAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS

COL12A1 PSD3 EXT1 NR4A1 DLC1 TNS1 HSP90AA1

6.96e-061771047M39245
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP2 RSPH4A ABCA13 ADGRV1 CSMD3 LRP1B SLC18A1 TRPM8 HSP90AA1

2.23e-10169103912bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 ABCA4 ABCA13 ADGRV1 CSMD3 LRP1B ARFGEF3

2.43e-0718410372cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 ABCA4 ABCA13 ADGRV1 CSMD3 LRP1B ARFGEF3

2.43e-071841037ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 ABCA4 ABCA13 ADGRV1 CSMD3 LRP1B ARFGEF3

2.43e-0718410372b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 NAALAD2 COL12A1 TRPC4 LAMA4 DLC1 LRP1

3.13e-07191103739092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 NAALAD2 COL12A1 TRPC4 LAMA4 DLC1 LRP1

3.13e-071911037107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 NAALAD2 COL12A1 TRPC4 LAMA4 DLC1 LRP1

3.13e-071911037bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 NAALAD2 COL12A1 TRPC4 LAMA4 DLC1 LRP1

3.13e-071911037ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 NAALAD2 COL12A1 TRPC4 LAMA4 DLC1 LRP1

3.24e-0719210375105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 NAALAD2 COL12A1 TRPC4 LAMA4 DLC1 LRP1

3.24e-071921037d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 PSD3 LAMA4 DLC1 LRP1

3.60e-071951037d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell5'-GW_trimst-2|5' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL3A1 COL12A1 LAMA4 RGN DLC1 P4HA1 HSP90AB1

3.99e-071981037677816ea6d1706d99b7757d43b6b375276b25639
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL3A1 NAALAD2 SDK2 PSD3 LAMA4 LRP1 TNS1

4.12e-07199103730d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial|6m / Sample Type, Dataset, Time_group, and Cell type.

COL3A1 P4HA2 COL12A1 LAMA4 NR4A1 JMJD1C DLC1

4.26e-0720010372cc98abf11f5b58707de45a2282f03d47f00f035
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial-Proteoglycan-expressing_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

COL3A1 P4HA2 COL12A1 LAMA4 NR4A1 JMJD1C DLC1

4.26e-0720010370f7431f670f3a175377cefae3479403a881bb8fb
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

KLHL10 CSMD3 LRP1B ADCY8 RBFOX1 ALK

1.36e-0615010360205318a870e091add66ee4305747dda9f51510d
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

COL3A1 SDK2 LAMA4 NOX1 PAK3 TNS1

1.91e-0615910363f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellVE-Treg-exh_CD4|VE / Condition, Cell_class and T cell subcluster

MINK1 VSIG1 TENT5C EXT1 NR4A1 CLPTM1L

2.54e-0616710361036ac1ef9440612500137af9d1929672b077e4d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 ADAD1 NAALAD2 COL12A1 LAMA4 LRP1

3.32e-061751036795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 LAMA4 DLC1 LRP1

4.04e-061811036c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 COL12A1 ABCA4 ABCA13 ADGRV1 ADCY8

4.04e-0618110369d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 LAMA4 DLC1 LRP1

4.04e-061811036c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 NAALAD2 COL12A1 TRPC4 LAMA4 LRP1

4.44e-061841036e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D231|Adult / Lineage, Cell type, age group and donor

ADGRV1 AQP3 PGC ITPR3 ARFGEF3 DLC1

5.17e-061891036dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 PSD3 LAMA4 DLC1 LRP1

5.33e-0619010362306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 NAALAD2 COL12A1 LAMA4 LRP1 PAK3

5.33e-061901036efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 PSD3 LAMA4 DLC1 LRP1

5.33e-0619010361f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 PSD3 LAMA4 LRP1

5.66e-0619210369093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 PSD3 LAMA4 LRP1

5.66e-0619210369ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

ADGRV1 PGC ADCY8 ITPR3 ARFGEF3 DLC1

5.66e-06192103658c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ADGRV1 ARFGEF3 ARHGDIG SLC18A1 PAK3 SMIM32

5.66e-0619210364d3a1c267739b1479217144656986972fc86db43
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL3A1 NAALAD2 LAMA4 CSMD3 DLC1 PAK3

5.83e-061931036549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 LAMA4 DLC1 LRP1

5.83e-061931036f1199518c3626fd29bfce65070dd21a660671213
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

COL3A1 COL12A1 LAMA4 NR4A1 ITPR3 DLC1

5.83e-061931036e1de67ddada87229f5db0ec193a6da8745a86a64
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal-choroid_plexus/mesenchymal-like_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

COL3A1 COL12A1 LAMA4 NR4A1 ITPR3 DLC1

5.83e-061931036b6f5a85210e60798205eaf5884cdb540f549d08a
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL3A1 COL7A1 COL12A1 TRPC4 LAMA4 RGN

6.01e-0619410362d66091097e106c7bee22e5281f50724700bdf8d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 LAMA4 DLC1 LRP1

6.01e-061941036e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 LAMA4 DLC1 LRP1

6.19e-061951036d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 LAMA4 DLC1 LRP1

6.19e-06195103649c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL3A1 P4HA2 COL7A1 ATP6V0C P4HA1 TNS1

6.19e-06195103678cfde21dde4b877fc76c8b0d5ddaabe44b912d7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 LAMA4 DLC1 LRP1

6.19e-061951036dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 LAMA4 DLC1 LRP1

6.19e-061951036edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 PSD3 LAMA4 LRP1

6.37e-061961036a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellMesenchymal_cells-Fibro/Chondro_p.|World / Lineage and Cell class

P4HA2 SDK2 COL12A1 STK32C P3H4 P4HA1

6.37e-061961036ddc168849e0e97005a111be004463bb72d433853
ToppCellfacs-Trachea|facs / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL3A1 HIVEP2 NR4A1 JMJD1C LRP1 HSP90AA1

6.37e-0619610368209f2b0f7efebaaf81d642d18a1aee8a9a8dcf6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 LAMA4 DLC1 LRP1

6.37e-061961036fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 LAMA4 DLC1 LRP1

6.37e-061961036802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 PSD3 LAMA4 LRP1

6.37e-0619610363e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 PSD3 LAMA4 LRP1

6.56e-0619710366d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 LAMA4 DLC1 LRP1

6.56e-061971036ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 LAMA4 DLC1 LRP1

6.56e-06197103637f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellControl-Classical_Monocyte-cMono_2|Classical_Monocyte / Disease condition and Cell class

RIPOR2 ATP5MK JMJD1C ALDH2 HSP90AA1 HSP90AB1

6.56e-061971036eb7610c9496a95a5fd866e16abcbc39b83abe617
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 LAMA4 EXT1 DLC1

6.56e-06197103680e153790cef37b743e22a7370ff5b3a6abf147d
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL3A1 COL12A1 PSD3 LAMA4 CSMD3 LRP1

6.75e-06198103609be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCellCOVID-19-kidney-Fibroblast-2|kidney / Disease (COVID-19 only), tissue and cell type

COL3A1 COL12A1 TRPC4 LAMA4 DLC1 LRP1

6.75e-061981036ca26ca460856b1faaa3e83766da6abdf63af2b51
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

COL3A1 COL12A1 PSD3 LAMA4 NR4A1 DLC1

6.95e-0619910365b9d355795dd03a22f0961dfd143425c367a4654
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL12A1 LAMA4 NR4A1 CSMD3 DLC1 PAK3

6.95e-0619910363835452e4848d7f7dd8651c17b746b271ef39688
ToppCell3'-GW_trimst-1.5|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL3A1 COL12A1 LAMA4 DLC1 P4HA1 RTL8C

6.95e-0619910368e69d718ed5b05b08550973c33c92f0c6bfccc68
ToppCellCOVID-19|World / group, cell type (main and fine annotations)

COL3A1 ATP6V0C P4HA1 LRP1 HSP90AA1 HSP90AB1

7.15e-062001036ac38a468559c33ee00152735ce6e408f3f48df84
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

COL3A1 NAALAD2 PSD3 LAMA4 LRP1 TNS1

7.15e-062001036bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Rectal_Adenocarcinoma-5|TCGA-Colorectal / Sample_Type by Project: Shred V9

SDK2 AQP3 SLC18A1 SLC16A14 PADI3

1.08e-051251035c82b4bddc98b2a2d2ee00c1392df86f9735c0623
ToppCellCOVID-19-kidney-Epithelial_Doublet|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCB5 CSMD3 LRP1B RBFOX1 ALK

1.30e-0513010351ff28e9d3dc9a791e07d815f8fbb48f75d3f275b
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCB5 CSMD3 LRP1B RBFOX1 ALK

2.43e-051481035d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellSevere-B_naive-5|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SDK2 ZNF607 ABCB5 PAK3 ALDH2

3.23e-051571035a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l32|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TENT5C CUL9 XYLB PHLPP2

3.41e-0579103411e92ae55dae24b6f73dd5a52e1c3c4e579ddf7b
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 ADGRV1 LRP1B ADCY8 TRPM8

3.53e-051601035c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 ADGRV1 LRP1B ADCY8 TRPM8

3.53e-05160103525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma|TCGA-Brain / Sample_Type by Project: Shred V9

CSMD3 ARFGEF3 ZFR2 PAK3 PHLPP2

3.64e-0516110355f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 COL12A1 ABCA13 ADCY8 SLC45A4

3.97e-051641035382e42701779d12a7948690b3be72d06dd75c8b4
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC4 STK32C NPHP4 SLC45A4 RBFOX1

4.46e-051681035b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC4 STK32C NPHP4 SLC45A4 RBFOX1

4.46e-051681035b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

TRPC4 LAMA4 RGN DLC1 TNS1

4.85e-051711035080003f698f867935c2bfc55d241d3650f45a0ab
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP2 CSMD3 LRP1B TRPM8 HSP90AA1

5.12e-05173103566f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP2 CSMD3 LRP1B TRPM8 HSP90AA1

5.12e-051731035649b08a409095592cccf31883be69c754411280d
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL3A1 TRPC4 PSD3 CSMD3 ALK

5.26e-051741035f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL3A1 NAALAD2 COL12A1 ADCY8 RBFOX1

5.26e-051741035a7ade7372e83edd4e3983e77f8417b51f0b47340
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

TMPRSS11E AQP3 LRP1 NIPAL2 PADI3

5.41e-0517510350cc215109d9915af47e4d0a120ce2e46910715fa
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 ADGRV1 CSMD3 LRP1B ADCY8

5.41e-051751035887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 DLC1 LRP1

5.56e-0517610359bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 TRPC4 DLC1 LRP1

5.56e-0517610353f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)|343B / Donor, Lineage, Cell class and subclass (all cells)

COL3A1 COL7A1 PSD3 NARS2 KDM4D

5.71e-051771035e55d21d4d61a069b9bbe0e7595fbfb7cfbacfd87
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-|343B / Donor, Lineage, Cell class and subclass (all cells)

COL3A1 COL7A1 PSD3 NARS2 KDM4D

5.71e-05177103543ba6f12c2fb32698a420bf799d46ac1b558f146
ToppCellEndothelial-Endothelial-C|Endothelial / shred on cell class and cell subclass (v4)

RIPOR2 ITGA6 AQP3 SLC45A4 ALDH2

5.71e-051771035b5b9278dfd76b1aacd88e5fe86e91a2c9b565f87
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 UPF1 ADGRV1 NR4A1 SLC45A4

6.02e-0517910356e965e424eebef50f0202cff75f458be395cfca1
ToppCellCOVID-19-kidney-Stressed_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

JMJD1C ABCG1 P4HA1 HSP90AA1 HSP90AB1

6.02e-051791035754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

COL12A1 LAMA4 ABCG1 RBFOX1 PAK3

6.02e-051791035e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL3A1 SDK2 LAMA4 ALDH2 TNS1

6.02e-051791035b559f5a72cc9e3e35d05cb539b5c2e006e56e652
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 LAMA4 LRP1 PAK3

6.18e-051801035c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 NAALAD2 COL12A1 TRPC4 DLC1

6.18e-051801035280ff5c8f292be1b88120db5ff1788b750644856
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 COL12A1 LAMA4 LRP1 PAK3

6.18e-05180103532c6a3886428d82fb4355d987c6d2645f333447b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 NAALAD2 COL12A1 TRPC4 DLC1

6.18e-051801035fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCellfacs-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL7A1 COL12A1 CSMD3 AQP3 LRP1B

6.18e-05180103572310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL7A1 COL12A1 TMPRSS11E AQP3 ITPR3

6.34e-051811035a5e770b5b5d57cbac18560828e89f7c96b687743
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL7A1 COL12A1 TMPRSS11E AQP3 ITPR3

6.34e-051811035504b1af1951a7a20ef5db69d84c20630ec64095b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL7A1 COL12A1 TMPRSS11E AQP3 ITPR3

6.34e-051811035a55ec36d2393f7a376feb42b22aee75dfdf4c383
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

RIPOR2 HIVEP2 ITGA6 ATP5MK AQP3

6.51e-0518210351aea96ee211f7b9caef7fd385233f51be6021a73
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 COL12A1 ABCA4 ABCA13 ADGRV1

6.51e-051821035eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RIPOR2 HIVEP2 ITGA6 ATP5MK AQP3

6.51e-051821035b427e43ee523a3ea9eca3207f3d82042f10f022a
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RIPOR2 HIVEP2 ITGA6 ATP5MK AQP3

6.51e-051821035c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RIPOR2 HIVEP2 ITGA6 ATP5MK AQP3

6.51e-0518210354cb182ef39be2044a6ad7266f332d4177591e550
DrugEpivincamine [6835-99-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A

RIPOR2 MINK1 NR4A1 NPHP4 DLC1 RBFOX1 XYLB TNS1 PHLPP2

3.20e-0720010396838_UP
DrugBiperiden hydrochloride [1235-82-1]; Up 200; 11.4uM; MCF7; HT_HG-U133A

GLB1L TRPC4 TRPC5 TENT5C NR4A1 NOX1 TNS1 PHLPP2

2.98e-0619510383321_UP
DrugF0447-0125; Down 200; 10uM; MCF7; HT_HG-U133A

MTA2 NAALAD2 GLB1L MINK1 NR4A1 HOXD3 PLCD1 PHLPP2

3.09e-0619610386396_DN
DrugNSC330499

HSP90AA1 HSP90AA2P HSP90AB1

3.11e-0671033CID000433447
DrugIsradipine [75695-93-1]; Up 200; 10.8uM; MCF7; HT_HG-U133A

CUL9 NR4A1 AQP3 LRP1B DLC1 NOX1 RBFOX1 ALK

3.21e-0619710385447_UP
DrugAjmalicine hydrochloride [4373-34-6]; Up 200; 10.2uM; MCF7; HT_HG-U133A

COL7A1 TRPC5 MINK1 TENT5C ITPR3 DLC1 PADI3 KDM4B

3.46e-0619910385459_UP
Drugphenyldichloroarsine

HSP90AA1 HSP90AA2P HSP90AB1

4.95e-0681033CID000012762
Drug5,8-quinolinedione

HSP90AA1 HSP90AA2P HSP90AB1

7.41e-0691033CID000388306
DrugKdel Sequence

P4HA2 ARHGDIG P4HA1 HSP90AA1 HSP90AA2P

9.06e-06621035CID000123910
DrugPu-3

HSP90AA1 HSP90AA2P HSP90AB1

1.44e-05111033CID000448965
Drug(-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; PC3; HT_HG-U133A

COL3A1 GLB1L PSD3 LAMA4 AQP3 DLC1 TNS1

1.61e-0517710374495_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A

RIPOR2 TENT5C EXT1 AQP3 ABCG1 TNS1 KDM4B

1.61e-0517710373993_UP
Drugmalotilate

COL3A1 P4HA2 COL7A1 COL12A1 P4HA1

1.77e-05711035CID000004006
Drug3-amino-5-chlorobenzoic acid

HSP90AA1 HSP90AA2P

2.03e-0521032CID010986726
Drugmonocillin III

HSP90AA1 HSP90AA2P

2.03e-0521032CID006478910
Drugpochonin A

HSP90AA1 HSP90AA2P

2.03e-0521032CID006478909
DrugPU-H71

HSP90AA1 HSP90AA2P

2.03e-0521032CID009549213
Drug9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine

HSP90AA1 HSP90AB1

2.03e-0521032DB02754
Drug1uyc

HSP90AA1 HSP90AA2P

2.03e-0521032CID000448969
DrugPU-9

HSP90AA1 HSP90AA2P

2.03e-0521032CID000448971
DrugP u 0

HSP90AA1 HSP90AA2P

2.03e-0521032CID000448974
Drug2qf6

HSP90AA1 HSP90AA2P

2.03e-0521032CID013373715
DrugGeldanamycin

HSP90AA1 HSP90AB1

2.03e-0521032DB02424
DrugCHEBI:42139

HSP90AA1 HSP90AA2P

2.03e-0521032CID011562562
Drug2qfo

HSP90AA1 HSP90AA2P

2.03e-0521032CID000600769
Drug3eko

HSP90AA1 HSP90AA2P

2.03e-0521032CID011160307
Drug8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE

HSP90AA1 HSP90AB1

2.03e-0521032DB07877
Drug1uyi

HSP90AA1 HSP90AA2P

2.03e-0521032CID005289232
Drug4-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOL

HSP90AA1 HSP90AB1

2.03e-0521032DB07594
DrugNSC683666

HSP90AA1 HSP90AA2P

2.03e-0521032CID005469153
DrugH 64

HSP90AA1 HSP90AA2P

2.03e-0521032CID006914564
DrugSureCN4151355

HSP90AA1 HSP90AA2P

2.03e-0521032CID015942101
Drug17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A

P4HA2 NAALAD2 TENT5C CUL9 P4HA1 NIPAL2 HSP90AB1

2.14e-0518510376973_UP
Drug17-AAG; Up 200; 1uM; PC3; HT_HG-U133A

P4HA2 MINK1 NR4A1 NOX1 SLC18A1 RAB3GAP2 LRP1

2.46e-0518910374430_UP
DrugMMTS

NR4A1 AQP3 HSP90AA1 HSP90AA2P

2.59e-05381034CID000099129
DrugDicumarol [66-76-2]; Up 200; 11.8uM; HL60; HT_HG-U133A

RIPOR2 LAMA4 ARHGDIG DLC1 HOXD3 RBFOX1 NIPAL2

2.72e-0519210372561_UP
DrugEtofenamate [30544-47-9]; Up 200; 10.8uM; PC3; HT_HG-U133A

AQP3 ARHGDIG ABCG1 DLC1 LRP1 PLCD1 ALK

2.81e-0519310373989_UP
DrugOmeprazole [73590-58-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A

COL7A1 NAALAD2 LAMA4 NR4A1 RBFOX1 ALDH2 ALK

2.91e-0519410374951_UP
DrugFludrocortisone acetate [514-36-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A

GLB1L LAMA4 EXT1 NR4A1 FER PLCD1 PADI3

2.91e-0519410373977_DN
DrugStachydrine hydrochloride; Down 200; 22.2uM; MCF7; HT_HG-U133A

GLB1L MINK1 ITGA6 MALT1 NIPAL2 PLCD1 KDM4B

2.91e-0519410372743_DN
DrugAcetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A

COL7A1 NAALAD2 GLB1L MINK1 PSD3 LAMA4 NR4A1

2.91e-0519410372223_UP
DrugHydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A

COL3A1 COL7A1 TRPC4 LAMA4 HOXD3 RBFOX1 XYLB

3.00e-0519510374746_UP
DrugGibberellic acid [77-06-5]; Down 200; 11.6uM; PC3; HT_HG-U133A

COL7A1 NOX1 RAB3GAP2 LRP1 PAK3 ALDH2 ALK

3.00e-0519510374234_DN
Druggenistein; Down 200; 1uM; MCF7; HG-U133A

COL7A1 GLB1L MINK1 NPHP4 NOX1 RBFOX1 NIPAL2

3.00e-051951037268_DN
DrugFluorometholone [426-13-1]; Up 200; 10.6uM; PC3; HT_HG-U133A

COL3A1 NR4A1 ABCG1 SLC18A1 RBFOX1 LRP1 NIPAL2

3.10e-0519610375771_UP
DrugMerbromin [129-16-8]; Up 200; 5uM; PC3; HT_HG-U133A

MINK1 LAMA4 ARHGDIG RBFOX1 LRP1 TRPM8 TNS1

3.10e-0519610373700_UP
DrugClofazimine [2030-63-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A

COL7A1 TFDP3 NR4A1 RBFOX1 PLCD1 ALDH2 PHLPP2

3.10e-0519610375642_UP
DrugTrimipramine maleate salt [521-78-8]; Down 200; 9.8uM; HL60; HT_HG-U133A

TRPC4 TRPC5 PSD3 LAMA4 EXT1 RBFOX1 XYLB

3.21e-0519710373004_DN
Drugcelecoxib; Down 200; 10uM; PC3; HG-U133A

COL3A1 COL7A1 AQP3 ARHGDIG PPP4C NIPAL2 TNS1

3.21e-051971037482_DN
Drugnovobiocin sodium, USP; Down 200; 100uM; PC3; HG-U133A

NR4A1 PPP4C NOX1 ZFR2 CD2BP2 LRP1 PLCD1

3.21e-051971037435_DN
DrugPraziquantel [55268-74-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A

RIPOR2 GLB1L LRP1B ARHGDIG ALK PADI3 KDM4B

3.21e-0519710373189_UP
DrugTiaprofenic acid [33005-95-7]; Up 200; 15.4uM; MCF7; HT_HG-U133A

COL7A1 NAALAD2 LAMA4 TENT5C NOX1 RAB3GAP2 PLCD1

3.31e-0519810374171_UP
DrugLomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; PC3; HT_HG-U133A

LAMA4 TFDP3 TENT5C ITPR3 NOX1 RBFOX1 XYLB

3.31e-0519810373723_UP
DrugPirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A

RIPOR2 MINK1 TENT5C AQP3 ITPR3 PLCD1 TNS1

3.31e-0519810372234_UP
DrugAntimycin A [1397-94-0]; Up 200; 7.2uM; PC3; HT_HG-U133A

LAMA4 NR4A1 ITPR3 RBFOX1 NIPAL2 XYLB ALK

3.31e-0519810375053_UP
Drugradicicol, diheterospora chlamydosporia; Up 200; 0.1uM; HL60; HT_HG-U133A

P4HA2 PSD3 NR4A1 NPHP4 ABCG1 NIPAL2 KDM4B

3.31e-0519810376178_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

TRPC4 EXT1 NR4A1 ITPR3 RBFOX1 TNS1 PHLPP2

3.42e-0519910374348_UP
DrugBrinzolamide [138890-62-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A

NAALAD2 HIVEP2 PSD3 NOX1 RBFOX1 PLCD1 XYLB

3.42e-0519910373230_UP
DrugCyproheptadine hydrochloride [969-33-5]; Down 200; 12.4uM; PC3; HT_HG-U133A

COL7A1 PNPLA4 MINK1 PSD3 UPF1 UBAP2L PAK3

3.42e-0519910376740_DN
DrugSolanine alpha [20562-02-1]; Up 200; 4.6uM; MCF7; HT_HG-U133A

MTA2 PSD3 TENT5C NR4A1 PLCD1 PADI3 KDM4B

3.42e-0519910372808_UP
DrugOxolinic acid [14698-29-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A

MINK1 TENT5C KLHL11 ARHGDIG DLC1 RBFOX1 ALK

3.42e-0519910372266_UP
DrugTheobromine [83-67-0]; Up 200; 22.2uM; HL60; HT_HG-U133A

RIPOR2 PNPLA4 TFDP3 EXT1 ABCG1 DLC1 KDM4B

3.42e-0519910372995_UP
DrugTobramycin [32986-56-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A

ITGA6 TENT5C MALT1 ARHGDIG ABCG1 NIPAL2 KDM4B

3.42e-0519910372841_DN
DrugTrimethadione [127-48-0]; Up 200; 28uM; PC3; HT_HG-U133A

COL3A1 RIPOR2 GLB1L LRP1 NIPAL2 PLCD1 TNS1

3.53e-0520010374086_UP
DrugAC1L9PMA

HSP90AA1 HSP90AA2P HSP90AB1

3.93e-05151033CID000451405
Drug$l^{1}-borane

TRPC4 TRPC5 ITPR3 PPP4C

4.67e-05441034CID006397184
Drugthiolutin

UPF1 HSP90AA1 HSP90AA2P

4.82e-05161033CID000006870
Drugdexamethasone 21-mesylate

NR4A1 HSP90AA1 HSP90AA2P

4.82e-05161033CID000063041
Drug4-hydroxyproline

COL3A1 P4HA2 COL7A1 COL12A1 P4HA1

5.87e-05911035CID000000825
Drugpochonin D

HSP90AA1 HSP90AA2P

6.06e-0531032CID006478913
Drugazaquinone

HSP90AA1 HSP90AA2P

6.06e-0531032CID000099132
Drugd 1 v

HSP90AA1 HSP90AA2P

6.06e-0531032CID000683940
DrugAC1MD0RC

HSP90AA1 HSP90AA2P

6.06e-0531032CID002829073
DrugNSC326198

COL3A1 ABCA4

6.06e-0531032CID005359777
DrugHM-9

HSP90AA1 HSP90AA2P

6.06e-0531032CID000433437
DrugGlyoxylspermidine

HSP90AA1 HSP90AA2P

6.06e-0531032CID000133564
DrugDCDD

ATP6V0C HSP90AA1 HSP90AA2P

8.27e-05191033CID000036613
Drugdimethyl pimelimidate

HSP90AA1 HSP90AA2P HSP90AB1

9.69e-05201033CID000065403
DrugNSC49633

COL3A1 COL7A1 COL12A1 NOX1

9.75e-05531034CID000023340
Drugberyllium fluoride

ABCB5 PPP4C HSP90AA1 HSP90AA2P HSP90AB1

1.06e-041031035CID000024589
Druggeldanamycin; Up 200; 1uM; HL60; HT_HG-U133A

P4HA2 HIVEP2 PSD3 NR4A1 LRP1 NIPAL2

1.13e-0416710366187_UP
Druggold nanoparticles

COL7A1 COL12A1 POLA1 AQP3 ADCY8 PIK3R4 PPP4C

1.20e-042431037CID000023985
DrugN-(5-methylisoxazol-3-yl)-2-(4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-ylthio)acetamide

HSP90AA1 HSP90AB1

1.21e-0441032ctd:C576667
Druguranyl chloride

HSP90AA1 HSP90AA2P

1.21e-0441032CID000082259
Drugmethoxyhydroquinone

HSP90AA1 HSP90AA2P

1.21e-0441032CID000069988
Drug11p110

HSP90AA1 HSP90AA2P

1.21e-0441032CID002382787
DrugATFP

COL3A1 COL7A1

1.21e-0441032CID000193783
Drugtamoxifen aziridine

HSP90AA1 HSP90AA2P HSP90AB1

1.30e-04221033CID003033894
DrugCCT018159

HSP90AA1 HSP90AA2P HSP90AB1

1.30e-04221033CID005327091
Drughydroxylysine

COL3A1 P4HA2 COL7A1 COL12A1 P4HA1

1.38e-041091035CID000001029
Drugtrichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A

TENT5C EXT1 NR4A1 AQP3 ABCG1 KDM4B

1.46e-0417510367073_UP
DrugS2A

HSP90AA1 HSP90AA2P HSP90AB1

1.49e-04231033CID016058643
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A

P4HA2 TRPC5 TENT5C MALT1 KDM4A HSP90AB1

1.55e-0417710366943_UP
Drugalpha-ketoglutarate

P4HA2 ETNPPL JMJD1C PTGR3 P4HA1 KDM4A KDM4B

1.58e-042541037CID000000051
DrugLG 5

COL3A1 LAMA4 ITGA6 PIK3R4

1.59e-04601034CID011840957
DrugUrsolic acid [77-52-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A

GLB1L PSD3 NR4A1 AQP3 NOX1 RBFOX1

1.81e-0418210362230_UP
Drugtrichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A

COL7A1 EXT1 NR4A1 AQP3 ABCG1 KDM4B

1.81e-0418210367503_UP
Drug2,7,8-trihydroxyanthraquinone

P4HA2 P4HA1

2.01e-0451032CID000065739
Drug1uyd

HSP90AA1 HSP90AA2P

2.01e-0451032CID000448970
DrugHCV-796

HSP90AA1 HSP90AA2P

2.01e-0451032CID011561383
DiseaseColorectal Carcinoma

COL3A1 COL7A1 ABCA4 ABCA13 ABCB5 STK32C CSMD3 ADCY8 ABCG1 DLC1 LRP1 ALDH2

5.73e-0670210212C0009402
DiseaseGranuloma, Plasma Cell

RANBP2 ALK

1.18e-0521022C0018199
Diseaseamyotrophic lateral sclerosis, age at onset

ST3GAL3 SLC18A1 KDM4A

1.77e-05151023EFO_0004847, MONDO_0004976
Diseasecortical thickness

P4HA2 RIPOR2 COL12A1 ABCA4 CUL9 EXT1 ADGRV1 JMJD1C SLC45A4 ABCG1 DLC1 LRP1 TNS1 KDM4B

2.94e-05111310214EFO_0004840
DiseaseTrichilemmal cyst

CLPTM1L PLCD1

3.54e-0531022HP_0025246
DiseaseColorectal Neoplasms

COL7A1 ABCA4 ABCA13 ABCB5 ABCG1 DLC1 ALDH2

5.14e-052771027C0009404
Diseasediffuse plaque measurement

SDK2 ABCA13 PSD3 CSMD3 LRP1B ARFGEF3 DLC1 BTNL2 RBFOX1 TNS1 HSP90AA4P

6.39e-0575810211EFO_0010699
DiseaseKi-1+ Anaplastic Large Cell Lymphoma

ALK HSP90AA1

7.07e-0541022C0206180
Diseasemigraine disorder, glucose measurement

ST3GAL3 JMJD1C KDM4A

1.68e-04311023EFO_0004468, MONDO_0005277
DiseaseInflammatory Myofibroblastic Tumor

RANBP2 ALK

1.76e-0461022C0334121
DiseaseCommon Migraine

LRP1 TRPM8

2.46e-0471022C0338480
Diseaseheparin cofactor 2 measurement

DLC1 PHLPP2

2.46e-0471022EFO_0008150
Diseasebeta-citrylglutamate measurement

NAALAD2 JMJD1C

2.46e-0471022EFO_0800060
Diseaseepilepsy (implicated_via_orthology)

ATP6V0C MINK1 ITGA6 LRP1B LRP1

2.62e-041631025DOID:1826 (implicated_via_orthology)
Diseasechildhood aggressive behaviour measurement

TENT5C ST3GAL3 DLC1 KDM4A

2.62e-04891024EFO_0007663
Diseaseurate measurement

P4HA2 COL7A1 RIPOR2 PSD3 EXT1 ADGRV1 JMJD1C RBFOX1 LRP1 ALDH2 KDM4B

2.72e-0489510211EFO_0004531
Diseaseasthma

ADAD1 P4HA2 HIVEP2 CSMD3 LRP1B JMJD1C BTNL2 FER LRP1 TRPM8

2.79e-0475110210MONDO_0004979
DiseasePARTINGTON X-LINKED MENTAL RETARDATION SYNDROME

POLA1 PAK3

3.27e-0481022C0796250
Diseasecancer (implicated_via_orthology)

ITGA6 ALK HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1

3.45e-042681026DOID:162 (implicated_via_orthology)
DiseaseAcute Confusional Migraine

LRP1 TRPM8

4.19e-0491022C0521664
DiseaseStatus Migrainosus

LRP1 TRPM8

4.19e-0491022C0338489
DiseaseAbdominal Migraine

LRP1 TRPM8

4.19e-0491022C0270858
DiseaseSick Headaches

LRP1 TRPM8

4.19e-0491022C0700438
DiseaseCervical Migraine Syndrome

LRP1 TRPM8

4.19e-0491022C0007852
DiseaseHemicrania migraine

LRP1 TRPM8

4.19e-0491022C0018984
Diseaseresponse to corticosteroid, age at assessment

HIVEP2 RBFOX1

5.23e-04101022EFO_0008007, GO_0031960
Diseasealopecia areata (is_marker_for)

KDM4A KDM4B

5.23e-04101022DOID:986 (is_marker_for)
Diseaseapolipoprotein A 1 measurement

COL7A1 TMPRSS11E PSD3 JMJD1C DLC1 SLC18A1 NANS BTNL2 FER LRP1

7.17e-0484810210EFO_0004614
Diseasepulmonary function measurement, forced expiratory volume, smoking behaviour measurement

TNS1 PADI3

7.64e-04121022EFO_0003892, EFO_0004314, EFO_0005671
Diseasenicotine dependence (implicated_via_orthology)

TRPC4 TRPC5

7.64e-04121022DOID:0050742 (implicated_via_orthology)
Diseasecoronary artery disease

P4HA2 HIVEP2 PSD3 DLC1 SLC18A1 RBFOX1 FER LRP1 ALDH2 TNS1 ALK KDM4B

8.61e-04119410212EFO_0001645
DiseaseMigraine Disorders

LRP1 TRPM8

9.00e-04131022C0149931
Diseasemelanoma

COL12A1 ADGRV1 CLPTM1L TRPM8

9.75e-041261024EFO_0000756
Diseasereticulocyte count

KLHL10 UBAP2 LAMA4 TENT5C JMJD1C ADCY8 NARS2 SLC45A4 KLHL11 TNS1 HSP90AB1

9.84e-04104510211EFO_0007986
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

MINK1 PSD3 JMJD1C SLC18A1

1.00e-031271024EFO_0008595, EFO_0020947
Disease1-methylurate measurement

PSD3 SLC18A1

1.05e-03141022EFO_0021173
Diseaseallergic rhinitis

ADAD1 LAMA4 DLC1 RBFOX1

1.19e-031331024EFO_0005854
DiseaseAnilide use measurement

LRP1 TRPM8

1.21e-03151022EFO_0009938
Diseaseisocitrate measurement

FER TRPM8

1.38e-03161022EFO_0010505
Diseasemigraine without aura, susceptibility to, 4

LRP1 TRPM8

1.38e-03161022MONDO_0011847
Diseasemelanoma

ABCB5 LRP1B KDM4A ALK KDM4B

1.73e-032481025C0025202
Diseaseautism spectrum disorder (implicated_via_orthology)

TRPC4 TRPC5 EXT1 ITPR3

1.94e-031521024DOID:0060041 (implicated_via_orthology)
Diseasefacial attractiveness measurement

EXT1 LRP1B

1.95e-03191022EFO_0009892
Diseaseintrahepatic cholangiocarcinoma (is_marker_for)

HSP90AA1 HSP90AB1

1.95e-03191022DOID:4928 (is_marker_for)
Diseaseintraocular pressure measurement

OR8H3 P4HA2 ABCA4 DLC1 RBFOX1 FER TNS1

1.97e-035091027EFO_0004695
Diseaseglucose measurement

PSD3 TENT5C ITPR3 STYXL1 KDM4A ALDH2

2.09e-033801026EFO_0004468
Diseasenucleotide measurement

STK32C RBFOX1 ALK

2.09e-03731023EFO_0010513
Diseaselung cancer (is_implicated_in)

TRPC4 LRP1B CLPTM1L

2.18e-03741023DOID:1324 (is_implicated_in)
Diseasejuvenile idiopathic arthritis

ABCA13 NPHP4 JMJD1C

2.18e-03741023EFO_0002609
Diseaseintellectual disability (implicated_via_orthology)

ATP6V0C HIVEP2 RBFOX1

2.26e-03751023DOID:1059 (implicated_via_orthology)
Diseasediastolic blood pressure, systolic blood pressure

NAALAD2 RIPOR2 TRPC4 SLC45A4 DLC1 RBFOX1 FER LRP1

2.29e-036701028EFO_0006335, EFO_0006336
DiseaseAntimigraine preparation use measurement

LRP1 TRPM8

2.38e-03211022EFO_0009939
Diseasehaptoglobin measurement

DLC1 PHLPP2

2.38e-03211022EFO_0004640
Diseasesex interaction measurement, bilirubin measurement

COL12A1 PSD3

2.61e-03221022EFO_0004570, EFO_0008343
DiseaseNonsyndromic Deafness

RIPOR2 ADGRV1 NARS2

2.81e-03811023C3711374
Diseasesphingomyelin measurement

TMPRSS11E MINK1 UPF1 JMJD1C RBFOX1

2.84e-032781025EFO_0010118
Diseaseliver fibrosis measurement

TMPRSS11E JMJD1C ITPR3

3.33e-03861023EFO_0010576
Diseaseepiandrosterone sulfate measurement

TMPRSS11E ALK

3.37e-03251022EFO_0021120

Protein segments in the cluster

PeptideGeneStartEntry
QSYDAVGVMFASIPG

ADCY8

976

P40145
VGVMFASIPGFADFY

ADCY8

981

P40145
AMDGFVSAEPDGATY

CSMD3

3576

Q7Z407
GQQYTFFSMDEPGSE

ABCA4

1411

P78363
PADFVMEVASGEYGD

ABCG1

321

P45844
MVDFPGYNLSGAVAS

BTNL2

1

Q9UIR0
PEGMFIVFTAIAYGA

ABCB5

951

Q2M3G0
GQEFYETSGTVNFMD

ADGRV1

1166

Q8WXG9
GIDSYVSPFEMNFLG

ABCA13

4641

Q86UQ4
ETVTTGNVMGPYFAF

ADAD1

116

Q96M93
GNVMGPYFAFCAVVD

ADAD1

121

Q96M93
SFQMYGEDFVPDIVT

ETNPPL

261

Q8TBG4
DSVYTGGTEVMVPSF

RANBP2

2776

P49792
AYETMAGAGVPFSAN

MTA2

561

O94776
FFYPYMEGASTGVLD

ITPR3

2221

Q14573
PSFSTFMDGYTGEFD

NR4A1

51

P22736
IVYGDQDPMGQTSFE

ABHD14B

156

Q96IU4
GFSMEVGQYIFVNCP

NOX1

316

Q9Y5S8
MSQYITVGSNPFTGF

RAB3GAP2

301

Q9H2M9
AVTGEFTPDLYGSQM

PAK3

86

O75914
ADISMIGQFGVGFYS

HSP90AB1

121

P08238
MAAPPGEYFSVGSQV

LSM12

1

Q3MHD2
GSNVDMFSVAVFGAY

LRP1B

2081

Q9NZR2
GYENFGNSFMVPVDA

MALT1

416

Q9UDY8
DPAMGKVFFTDYGQI

LRP1

331

Q07954
MAGPESDAQYQFTGI

ATP5MK

1

Q96IX5
STDAGIAFAPVYSMG

JMJD1C

2081

Q15652
GEYIASGQVTFMGFK

CFAP52

76

Q8N1V2
QSFGAVTPGYDFMAR

PNPLA4

76

P41247
TQEAGEFMITFPYGY

KDM4A

261

O75164
ITQEAGEFMITFPYG

KDM4B

261

O94953
QEAGEFMVTFPYGYH

KDM4D

266

Q6B0I6
FFDMNIFEDGPYEVG

ITGA6

226

P23229
VYVGGNFVESMAPAS

HOXD3

356

P31249
GSVPEGTEMFEVYGT

PADI3

31

Q9ULW8
IYDNVFDGSGTDMEP

POLA1

1291

P09884
TFDAGSPGFQLRYMV

NPHP4

711

O75161
TGPYVIGFMDSFVNV

OR8H3

146

Q8N146
NYMSDVEAGGATVFP

P4HA2

456

O15460
GTPGQAFYEMASFSE

PLCD1

511

P51178
YMSDVSAGGATVFPE

P4HA1

456

P13674
PMFFYVTQGQEEIAS

UPF1

756

Q92900
GDAELYGPFTSAQMQ

CD2BP2

291

O95400
VTVLGNFIYAMGGFD

KLHL10

381

Q6JEL2
ESYVYVAGSMEPGFA

KLHL11

406

Q9NVR0
PDYTEDVGFDIGQAM

EXT1

201

Q16394
TTYKVNVFGMFDGGE

COL12A1

1151

Q99715
MVGSYGPSAQEYEFV

ARHGDIG

166

Q99819
DNMYRFEGTGFSNIP

FER

511

P16591
DYSMGKGQAPVFDVF

ARFGEF3

1321

Q5TH69
GLYTTVDFGPADNMT

GLB1L

231

Q6UWU2
DSSYMPARVVVFGGD

CUL9

1226

Q8IWT3
SMDGGFQFSYGNPEL

COL3A1

1331

P02461
GMDSVQTFFAVDDGP

COL7A1

1206

Q02388
ADISMIGQFGVGFYS

HSP90AA1

126

P07900
ADISMIGQFSVGFYS

HSP90AA4P

66

Q58FG1
YMVSVAAFNAAGDGP

SDK2

1696

Q58EX2
ADISMIGQFGVSFYS

HSP90AA2P

126

Q14568
FEGPMETGTYFSTEG

LAMA4

1641

Q16363
FTMFVDLGIYQPGGS

MINK1

951

Q8N4C8
PEFIVQTGSYMFVDE

RTL8C

41

A6ZKI3
MESAFYFEQAGVGLG

RSPH4A

316

Q5TD94
TYGVGAMNAFAPLTD

RBFOX1

351

Q9NWB1
PSVAMEGVRAGYFFS

TATDN3

176

Q17R31
GFSSGYFSLMPVVTE

SLC16A14

416

Q7RTX9
EVMSGAFTQVFTFGP

NARS2

226

Q96I59
LMAVGETGNFAAYGF

NIPAL2

96

Q9H841
VGDNPMSDVYGANLF

HDHD5

311

Q9BXW7
MYGDIFNATGGPEAA

SMIM32

1

A0A1B0GUA5
YAEEVGIFFTASGMD

NANS

101

Q9NR45
EVAVAGFGYDMSTPN

ST3GAL3

316

Q11203
GRYFAGTMAEETAPA

RGN

111

Q15493
RVGMYLEGFDPFNQS

DLC1

771

Q96QB1
YPFDVEDMTASSGAG

RIPOR2

316

Q9Y4F9
FHPTVIGESMYGDFE

TENT5C

206

Q5VWP2
YMAPEIFHSFVNGGT

STK32C

256

Q86UX6
AFGEVYEGQVSGMPN

ALK

1126

Q9UM73
YFIQPTVFGDVQDGM

ALDH2

396

P05091
MGFNSGYAVNPARDF

AQP3

206

Q92482
GLMPEFQFGTYSESE

CLPTM1L

376

Q96KA5
YIAPERFVDGGMFAT

PIK3R4

196

Q99570
AVFYTDFMGQVIFEG

SLC45A4

526

Q5BKX6
ASYEFQPGDVMFVTG

TMPRSS11E

301

Q9UL52
FSTQGMGTFNPADYS

UBAP2

186

Q5T6F2
MATSQYFDFAQGGGP

ZFR2

1

Q9UPR6
SGPEYASFFAVMGAS

ATP6V0C

6

P27449
EMEPISIYFSQGGQA

VSIG1

66

Q86XK7
FSAQGMGTFNPADYA

UBAP2L

191

Q14157
EPGTNFVYAQFDGIM

PGC

166

P20142
DSFAEGVGAVYGMFD

PHLPP2

806

Q6ZVD8
VNVSMDTGPFFAGDA

STYXL1

191

Q9Y6J8
PNVGGYFVDKFVATM

P3H4

281

Q92791
EFVFSYGPEKIQGME

TNS1

301

Q9HBL0
GNLGFYFDVMEITPE

XYLB

371

O75191
MSYGSITFGDVAIDF

ZNF607

1

Q96SK3
EPYVTEMAQGTFGGV

TFDP3

326

Q5H9I0
TVGQAVAYMAPGSFA

PTGR3

116

Q8N4Q0
FAGPYFVSEDNMAFG

TMEM222

86

Q9H0R3
FTEFVGATMFGTYNV

TRPC5

596

Q9UL62
MFGQVPSDVDGTTYD

TRPM8

911

Q7Z2W7
FDERMTGSDDVFYPG

HIVEP2

566

P31629
FRVGGDVPETNYLFM

PPP4C

66

P60510
VTNEFPEYGTMEEGG

PSD3

56

Q9NYI0
EFTEFVGATMFGTYN

TRPC4

591

Q9UBN4
FGSVMYEFVGKSAPF

SLC18A1

246

P54219
YNAFSAQGMPEGDLV

NAALAD2

151

Q9Y3Q0