Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpoly(G) binding

HNRNPDL DAZAP1

5.35e-0410702GO:0034046
GeneOntologyMolecularFunctiontranscription coactivator activity

BCL9L ELOB KMT2C RERE ZMIZ1 ARID1A

6.74e-04303706GO:0003713
GeneOntologyMolecularFunctiontranscription coregulator activity

BCL9L ELOB KMT2C PIAS3 RERE ZMIZ1 RUNX1T1 ARID1A

7.63e-04562708GO:0003712
GeneOntologyMolecularFunctiontype II transforming growth factor beta receptor binding

TGFB2 TGFBR3

7.82e-0412702GO:0005114
GeneOntologyMolecularFunctionbeta-catenin binding

BCL9L TCF7L2 ESR1 CDHR5

8.38e-04120704GO:0008013
DomainDUF4599

SPATA31D4 SPATA31D3 SPATA31C2

9.92e-0612683PF15371
DomainDUF4599

SPATA31D4 SPATA31D3 SPATA31C2

9.92e-0612683IPR027970
Domainzf-MIZ

PIAS3 ZMIZ1

2.71e-047682PF02891
DomainZF_SP_RING

PIAS3 ZMIZ1

2.71e-047682PS51044
DomainZnf_MIZ

PIAS3 ZMIZ1

3.61e-048682IPR004181
DomainZF_PHD_2

KMT2C BAZ2B PHF3 ASXL3

3.99e-0495684PS50016
DomainZF_PHD_1

KMT2C BAZ2B PHF3 ASXL3

4.15e-0496684PS01359
Domain-

GATAD2A ESR1 RERE

1.17e-03576833.30.50.10
DomainZnf_NHR/GATA

GATAD2A ESR1 RERE

1.23e-0358683IPR013088
DomainZnf_GATA

GATAD2A RERE

1.33e-0315682IPR000679
DomainGATA

GATAD2A RERE

1.33e-0315682PF00320
DomainGATA_ZN_FINGER_1

GATAD2A RERE

1.52e-0316682PS00344
DomainGATA_ZN_FINGER_2

GATAD2A RERE

1.52e-0316682PS50114
DomainPHD

KMT2C BAZ2B PHF3

2.58e-0375683PF00628
DomainZnf_PHD-finger

KMT2C BAZ2B PHF3

3.00e-0379683IPR019787
DomainPHD

KMT2C BAZ2B PHF3

4.19e-0389683SM00249
DomainZnf_PHD

KMT2C BAZ2B PHF3

4.46e-0391683IPR001965
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

HIVEP3 KMT2C TCF7L2 DAZAP1 MAP1B FAM120C DTNA BICRA MINK1 HECTD4 SRCIN1 RERE ZMIZ1 ARID1A CLEC16A CEP170B

5.01e-081489721628611215
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

JCAD TCF7L2 AFF2 PIAS3 BICRA ESR1 FAM186B ZNF804A FHIP1A

2.66e-0743072935044719
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

BCL9L KMT2C TMEM201 TCF7L2 DAZAP1 CLCN7 ZMIZ1 ARID1A NUP160

4.42e-0745772932344865
Pubmed

Interaction network of human early embryonic transcription factors.

BCL9L KMT2C TCF7L2 BICRA ASXL3 RERE ZMIZ1 ARID1A

6.78e-0735172838297188
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

HNRNPDL ELOB KMT2C TMEM201 TCF7L2 GATAD2A BAZ2B PHF3 SF3A1 NOL9 ZFC3H1 ARID1A SF3A2

2.27e-061294721330804502
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HIVEP3 KMT2C CLCN7 KALRN BICRA CTDP1 HECTD4 SHC1 ARHGAP17 IRS2 ARID1A CEP170B

2.64e-061105721235748872
Pubmed

RUNX1T1, a potential prognostic marker in breast cancer, is co-ordinately expressed with ERα, and regulated by estrogen receptor signalling in breast cancer cells.

ESR1 RUNX1T1

4.23e-06272234264479
Pubmed

Essential domains of the PRP21 splicing factor are implicated in the binding to PRP9 and PRP11 proteins and are conserved through evolution.

SF3A1 SF3A2

4.23e-0627228718683
Pubmed

Combined biochemical and electron microscopic analyses reveal the architecture of the mammalian U2 snRNP.

SF3A1 SF3A2

4.23e-06272210385517
Pubmed

KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function.

KMT2C ESR1

4.23e-06272229755131
Pubmed

Linkage of rapid estrogen action to MAPK activation by ERalpha-Shc association and Shc pathway activation.

ESR1 SHC1

4.23e-06272211773443
Pubmed

Loss of type III transforming growth factor beta receptor expression increases motility and invasiveness associated with epithelial to mesenchymal transition during pancreatic cancer progression.

TGFB2 TGFBR3

1.27e-05372217999987
Pubmed

Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling.

TGFB2 TGFBR3

1.27e-05372212958365
Pubmed

A role for Cajal bodies in the final steps of U2 snRNP biogenesis.

SF3A1 SF3A2

1.27e-05372215316075
Pubmed

Activation of estrogen receptor blocks interleukin-6-inducible cell growth of human multiple myeloma involving molecular cross-talk between estrogen receptor and STAT3 mediated by co-regulator PIAS3.

PIAS3 ESR1

1.27e-05372211429412
Pubmed

MiR-193b regulates early chondrogenesis by inhibiting the TGF-beta2 signaling pathway.

TGFB2 TGFBR3

1.27e-05372225728278
Pubmed

Betaglycan alters NFκB-TGFβ2 cross talk to reduce survival of human granulosa tumor cells.

TGFB2 TGFBR3

1.27e-05372223322721
Pubmed

Interaction domains and nuclear targeting signals in subunits of the U2 small nuclear ribonucleoprotein particle-associated splicing factor SF3a.

SF3A1 SF3A2

1.27e-05372221349847
Pubmed

Betaglycan blocks metastatic behaviors in human granulosa cell tumors by suppressing NFκB-mediated induction of MMP2.

TGFB2 TGFBR3

1.27e-05372225128652
Pubmed

The insulin-like growth factor-1 pathway mediator genes: SHC1 Met300Val shows a protective effect in breast cancer.

SHC1 IRS2

1.27e-05372215308584
Pubmed

Inhibition of insulin-like growth factor-I signaling by ethanol in neuronal cells.

SHC1 IRS2

1.27e-05372211505033
Pubmed

Estrogen receptor-alpha regulates the degradation of insulin receptor substrates 1 and 2 in breast cancer cells.

ESR1 IRS2

1.27e-05372212821935
Pubmed

The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor alpha to the plasma membrane.

ESR1 SHC1

1.27e-05372214764897
Pubmed

Long-term estradiol deprivation in breast cancer cells up-regulates growth factor signaling and enhances estrogen sensitivity.

ESR1 SHC1

1.27e-05372216113100
Pubmed

Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins.

HNRNPDL SF3A1 SF3A2

1.27e-052272326420826
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

HNRNPDL ELOB KMT2C TCF7L2 GATAD2A DAZAP1 BAZ2B BICRA SF3A1 ARID1A SF3A2

1.60e-051103721134189442
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

BCL9L CCDC8 LRRIQ1 RUNX1T1 DENND3

1.65e-0515272534299191
Pubmed

WW domains provide a platform for the assembly of multiprotein networks.

DAZAP1 SF3A1 GAS7 ARID1A SF3A2

1.76e-0515472516055720
Pubmed

Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.

TCF7L2 ESR1 IRS2

1.89e-052572318992263
Pubmed

Large-scale genotyping identifies 41 new loci associated with breast cancer risk.

TCF7L2 ESR1 ZMIZ1 NOBOX

1.94e-057672423535729
Pubmed

Cancer gene mutation frequencies for the U.S. population.

KMT2C ARID1A

2.53e-05472234645806
Pubmed

Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo.

SF3A1 SF3A2

2.53e-05472215647371
Pubmed

A positive feedback loop of ER-α36/EGFR promotes malignant growth of ER-negative breast cancer cells.

ESR1 SHC1

2.53e-05472220935677
Pubmed

Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart.

TGFB2 TGFBR3

2.53e-05472210092230
Pubmed

Endothelial angiogenesis is directed by RUNX1T1-regulated VEGFA, BMP4 and TGF-β2 expression.

TGFB2 RUNX1T1

2.53e-05472228640846
Pubmed

Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity.

PIAS3 ESR1

2.53e-05472215961505
Pubmed

Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation.

SF3A1 SF3A2

2.53e-05472211533230
Pubmed

TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling.

TGFB2 TGFBR3

2.53e-05472224161934
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

HNRNPDL CCDC8 AFF2 MINK1 PODXL2 LYSMD4 CLEC16A SDK1 NUP160

3.21e-0577772935844135
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

CCDC8 PHF3 HECTD4 ZFC3H1 ARID1A NUP160 MAP3K4

3.59e-0544072734244565
Pubmed

Genetic susceptibility to keloid disease: transforming growth factor beta receptor gene polymorphisms are not associated with keloid disease.

TGFB2 TGFBR3

4.21e-05572215009106
Pubmed

Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites.

TGFB2 TGFBR3

4.21e-0557228106553
Pubmed

Crystal structure of a beta-catenin/BCL9/Tcf4 complex.

BCL9L TCF7L2

4.21e-05572217052462
Pubmed

Comprehensive comparative homeobox gene annotation in human and mouse.

CDX1 NOBOX

4.21e-05572226412852
Pubmed

Myeloid translocation gene family members associate with T-cell factors (TCFs) and influence TCF-dependent transcription.

TCF7L2 RUNX1T1

4.21e-05572218039847
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

HNRNPDL ELOB DAZAP1 PIAS3 PHF3 ZFC3H1 ARID1A

4.31e-0545372729656893
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

BCL9L ELOB KMT2C GATAD2A DAZAP1 ARID1A NUP160

5.37e-0546972727634302
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

BCL9L ELOB KMT2C FAM120C PHF3 ESR1 MINK1 NOL9 ZFC3H1 FHIP1A SF3A2 CEP170B

5.43e-051497721231527615
Pubmed

The soluble exoplasmic domain of the type II transforming growth factor (TGF)-beta receptor. A heterogeneously glycosylated protein with high affinity and selectivity for TGF-beta ligands.

TGFB2 TGFBR3

6.31e-0567227852346
Pubmed

A novel role for protein inhibitor of activated STAT (PIAS) proteins in modulating the activity of Zimp7, a novel PIAS-like protein, in androgen receptor-mediated transcription.

PIAS3 ZMIZ1

6.31e-05672220159969
Pubmed

Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor.

TGFB2 TGFBR3

6.31e-05672211157754
Pubmed

Functional association of U2 snRNP with the ATP-independent spliceosomal complex E.

SF3A1 SF3A2

6.31e-05672210882114
Pubmed

Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.

TGFBR3 TCF7L2

6.31e-05672223209189
Pubmed

Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.

DTNA SRCIN1 CLEC16A CEP170B

8.26e-0511072427889896
Pubmed

Genome-wide SNP genotyping study using pooled DNA to identify candidate markers mediating susceptibility to end-stage renal disease attributed to Type 1 diabetes.

IRS2 ZMIZ1

8.82e-05772219929986
Pubmed

Identification of two distinct functions for TGF-beta in early mouse development.

TGFB2 TGFBR3

8.82e-0577229921650
Pubmed

Effects of TGFbeta2 on wild-type and Tgfbr3 knockout mouse fetal testis.

TGFB2 TGFBR3

8.82e-05772223303681
Pubmed

Vitamin D deficiency causes airway hyperresponsiveness, increases airway smooth muscle mass, and reduces TGF-β expression in the lungs of female BALB/c mice.

TGFB2 TGFBR3

8.82e-05772224760528
Pubmed

Expression of TGF-beta s and their receptors during implantation and organogenesis of the mouse embryo.

TGFB2 TGFBR3

8.82e-0577227813789
Pubmed

Genetic variation in candidate obesity genes ADRB2, ADRB3, GHRL, HSD11B1, IRS1, IRS2, and SHC1 and risk for breast cancer in the Cancer Prevention Study II.

SHC1 IRS2

8.82e-05772218611262
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

JCAD BCL9L MAP1B KALRN FAM120C DTNA MINK1 SRCIN1 CLEC16A CEP170B

1.16e-041139721036417873
Pubmed

ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation.

PIAS3 ESR1

1.17e-04872211117529
Pubmed

RACK1-mediated integration of adhesion and insulin-like growth factor I (IGF-I) signaling and cell migration are defective in cells expressing an IGF-I receptor mutated at tyrosines 1250 and 1251.

SHC1 IRS2

1.17e-04872215611085
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

SPATA31D4 SPATA31D3 KMT2C KALRN PHF3

1.26e-0423372537704626
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

AFF2 KALRN ASXL3 ESR1 ZMIZ1 FHIP1A DENND3

1.48e-0455272710737800
Pubmed

Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development.

ESR1 IRS2

1.51e-04972217662267
Pubmed

Identification of a link between Wnt/β-catenin signalling and the cell fusion pathway.

BCL9L TCF7L2

1.51e-04972222109522
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

HNRNPDL GATAD2A DAZAP1 MAP1B BAZ2B PHF3 BICRA SF3A1 ARID1A

1.53e-0495472936373674
Pubmed

Human transcription factor protein interaction networks.

BCL9L KMT2C CCDC8 TCF7L2 GATAD2A DTNA BICRA ESR1 RERE ZMIZ1 ARID1A

1.64e-041429721135140242
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

JCAD KMT2C TCF7L2 GATAD2A BICRA ARID1A

1.79e-0439872635016035
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

HNRNPDL DAZAP1 MAP1B BICRA SF3A1 SF3A2

1.81e-0439972635987950
Pubmed

Aurora kinase-A overexpression in mouse mammary epithelium induces mammary adenocarcinomas harboring genetic alterations shared with human breast cancer.

TCF7L2 ESR1

1.88e-041072227624071
Pubmed

Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.

ESR1 SHC1

1.88e-041072224051437
Pubmed

The core component of the mammalian SWI/SNF complex SMARCD3/BAF60c is a coactivator for the nuclear retinoic acid receptor.

ESR1 ARID1A

1.88e-041072217363140
Pubmed

A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.

SF3A1 SF3A2

1.88e-041072211500380
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

HNRNPDL PHF3 SF3A1 NAF1 MINK1 CTDP1 IRS2 RERE

1.98e-0477472815302935
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

GATAD2A BAZ2B SF3A1 RUNX1T1 ARID1A NUP160

2.13e-0441172635182466
Pubmed

SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation.

ELOB IRS2

2.30e-041172212052866
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

HNRNPDL BCL9L DAZAP1 BICRA ARHGAP17 ARID1A

2.54e-0442572624999758
Pubmed

Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.

KMT2C GATAD2A ARID1A

2.54e-045972328813667
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

HNRNPDL ELOB DAZAP1 GLB1 MAP1B SF3A1 ARHGAP17 SF3A2

2.67e-0480972832129710
Pubmed

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma.

GAS7 NUP160

2.75e-041272225173106
Pubmed

Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2).

ELOB FBXO31

2.75e-041272225505247
Pubmed

Accelerated failure time models provide a useful statistical framework for aging research.

SHC1 IRS2

2.75e-041272219007875
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

KALRN PHF3 MINK1 SRCIN1 CEP170B

2.99e-0428172528706196
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

JCAD DAZAP1 PIAS3 KALRN HECTD4 USP25 GAS7 ZFC3H1 ARID1A SF3A2

3.06e-041285721035914814
Pubmed

Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.

HNRNPDL GATAD2A SF3A1 CTDP1 ARID1A

3.09e-0428372518854154
Pubmed

Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis.

KMT2C ESR1

3.25e-041372221502505
Pubmed

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.

KALRN RERE

3.25e-041372224586183
Pubmed

Suppressor of Cytokine Signaling (SOCS) 5 utilises distinct domains for regulation of JAK1 and interaction with the adaptor protein Shc-1.

ELOB SHC1

3.25e-041372223990909
Pubmed

Computational and experimental studies on human misshapen/NIK-related kinase MINK-1.

MAP1B MINK1

3.25e-041372215032605
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

JCAD BCL9L IRS2 ARID1A NUP160 CEP170B

3.29e-0444672624255178
Pubmed

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.

RERE ZMIZ1 ZNF804A

3.39e-046572323453885
Pubmed

A bead-based approach for large-scale identification of in vitro kinase substrates.

HNRNPDL SF3A1 NAF1 ZFC3H1

3.73e-0416372422113938
Pubmed

Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos.

TGFB2 TGFBR3

3.78e-041472212773577
Pubmed

A genome-wide association study of optic disc parameters.

TGFBR3 RERE

3.78e-041472220548946
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

ELOB MAP1B KALRN SF3A1 HECTD4 PODXL2 ARID1A SF3A2 PLXNB1

3.88e-04108272938697112
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

GLB1 MAP1B MINK1 NOL9 CLEC16A DENND3 PLXNB1

3.97e-0465072738777146
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

JCAD CCDC8 MAP1B PHF3 MINK1 ARHGAP17 IRS2 CEP170B

4.04e-0486172836931259
Pubmed

A multilocus candidate approach identifies ACE and HIF1A as susceptibility genes for cellulite.

TGFB2 ESR1

4.36e-041572220059631
InteractionNUP35 interactions

HIVEP3 BCL9L KMT2C TMEM201 TCF7L2 DAZAP1 ESR1 ZMIZ1 ARID1A NUP160

1.72e-064246910int:NUP35
InteractionERG interactions

HNRNPDL KMT2C TCF7L2 PIAS3 BICRA RERE ARID1A

1.11e-05223697int:ERG
InteractionGSC interactions

BCL9L KMT2C TCF7L2 ASXL3 RERE

1.21e-0587695int:GSC
InteractionCEBPA interactions

TGFB2 HNRNPDL ELOB KMT2C CDX1 TCF7L2 GATAD2A DAZAP1 BAZ2B BICRA SF3A1 ESR1 ARID1A SF3A2 NUP160

1.61e-0512456915int:CEBPA
InteractionCRX interactions

BCL9L KMT2C TCF7L2 BICRA RERE ZMIZ1 ARID1A

2.58e-05254697int:CRX
InteractionEGR2 interactions

BCL9L KMT2C TCF7L2 BICRA RERE ARID1A

2.63e-05171696int:EGR2
InteractionTLE3 interactions

TGFB2 BCL9L TCF7L2 BAZ2B ESR1 RERE ZMIZ1 ARID1A

4.22e-05376698int:TLE3
InteractionTBR1 interactions

BCL9L KMT2C TCF7L2 ZMIZ1 ARID1A

4.28e-05113695int:TBR1
InteractionRAC1 interactions

CCDC8 TCF7L2 DAZAP1 PIAS3 CLCN7 KALRN DTNA ESR1 MINK1 ARHGAP17 NUP160 PLXNB1 MAP3K4

5.58e-0510636913int:RAC1
InteractionSNRNP40 interactions

HNRNPDL BCL9L GATAD2A DAZAP1 BAZ2B SF3A1 NOL9 ZFC3H1 ARID1A SF3A2

5.87e-056376910int:SNRNP40
InteractionSP7 interactions

BCL9L KMT2C TCF7L2 BICRA RERE ZMIZ1 ARID1A

8.04e-05304697int:SP7
InteractionSAR1A interactions

AFF2 DAZAP1 DTNA PODXL2 LYSMD4 CLEC16A NUP160

1.22e-04325697int:SAR1A
InteractionNCBP2 interactions

CCDC8 SF3A1 ESR1 ZFC3H1 SF3A2

1.22e-04141695int:NCBP2
InteractionAR interactions

BCL9L KMT2C TCF7L2 DAZAP1 PIAS3 PHF3 ESR1 HECTD4 SHC1 RERE ZMIZ1 ARID1A

1.24e-049926912int:AR
InteractionAFDN interactions

ILDR2 JCAD CCDC8 DTNA ESR1 MINK1 SDK1

1.42e-04333697int:AFDN
InteractionBUB3 interactions

KMT2C MAP1B ASXL3 RERE ZFC3H1 SF3A2

1.43e-04232696int:BUB3
GeneFamilyZinc fingers MIZ-type

PIAS3 ZMIZ1

1.10e-04742285
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

GATAD2A RERE

5.43e-041542282
GeneFamilyPHD finger proteins

KMT2C BAZ2B PHF3

1.19e-039042388
CoexpressionHALLMARK_UV_RESPONSE_DN

TGFBR3 PIAS3 MAP1B KALRN PHF3 ZMIZ1

2.64e-06144716M5942
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

TGFB2 HNRNPDL TGFBR3 TCF7L2 MAP1B BAZ2B PHF3 ZMIZ1 ZNF804A CLEC16A NUP160 MAP3K4

2.97e-068567112M4500
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

TGFB2 HNRNPDL TCF7L2 MAP1B BAZ2B PHF3 ZMIZ1 ZNF804A CLEC16A

4.61e-06466719M13522
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_500

CCDC8 SHC1 PODXL2 RUNX1T1

9.82e-0642684gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500_k5
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

HIVEP3 MAP1B KALRN ASXL3 GAS7 SRCIN1 RUNX1T1 SDK1

1.24e-09200728bad32a95b759fad509401b07bc96a56687c2a592
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 TGFBR3 MAP1B PCARE ZNF804A

1.09e-05180725d685fa2b013bc085dbef7c40956ed3043f83e483
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFBR3 MAP1B KALRN SHC1 RUNX1T1

1.18e-051837254d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 TGFBR3 MAP1B PCARE ZNF804A

1.31e-0518772524c2a3962da364e46e98abeab5f8234376fa26bb
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 TGFBR3 MAP1B PCARE ZNF804A

1.49e-05192725ef0aba777072429a6ab7dcfcc305673975946580
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB2 ILDR2 PODXL2 IRS2 PLXNB1

1.49e-051927250dc1f46e40346ed0b286e53b106a812441575100
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 TGFBR3 MAP1B PCARE ZNF804A

1.53e-051937253eaa0461618582a1754400624350d269d24e750a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 JCAD TGFBR3 KALRN RUNX1T1

1.57e-05194725b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DTNA ASXL3 GAS7 RUNX1T1 SDK1

1.57e-0519472589b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB2 TGFBR3 AFF2 MAP1B IRS2

1.61e-051957255c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B KALRN DTNA RUNX1T1 ZNF804A

1.65e-051967251522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B KALRN DTNA RUNX1T1 ZNF804A

1.65e-051967251c8294014713684b50885e638668f2ce75f357f0
ToppCellMild|World / Condition, Lineage, Cell class and cell subclass

KALRN PHF3 SF3A1 MINK1 SF3A2

1.69e-05197725476b0d0389f9fcd4614f6bb1f494281f467f6730
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TGFBR3 MAP1B GAS7 RUNX1T1 SDK1

1.81e-05200725389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TGFBR3 MAP1B GAS7 PODXL2

7.41e-051387248d70e64843f7c3be8ee4203cc126fdf1001f0df5
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

LRRIQ1 FAM186B SDK1 PLXNB1

1.19e-0415672410d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

HECTD4 ARID1A FAM186B PLXNB1

1.51e-0416672432d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFB2 MAP1B GAS7 SRCIN1

1.58e-0416872495dc690c1987b05685d36e6bb20eb79308696e30
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBR3 TCF7L2 KALRN MINK1

1.58e-04168724e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM120C DTNA AK9 ITIH6

1.62e-04169724606aa4ff25380d9470ec116ca86cd20f8b19587a
ToppCellEndothelial-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

TGFBR3 MAP1B KALRN RUNX1T1

1.62e-041697248889c9e8af1ab0b093d57b69abd80b59b3461be9
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM120C DTNA AK9 ITIH6

1.62e-04169724052aae2af5446a0de071d5dda5381b0b9a0ed54d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 MAP1B KALRN GAS7

1.66e-04170724dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 TGFBR3 MAP1B PCARE

1.66e-0417072460bbd738c12e64e483485586c30057304884f5a6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 MAP1B KALRN GAS7

1.66e-041707246035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 MAP1B KALRN GAS7

1.66e-04170724c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

JCAD TMEM201 TCF7L2 ZNF804A

1.69e-0417172487d652afbb375f8ee50e5faecf6085630cd2163c
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

TGFB2 ILDR2 DTNA SDK1

1.73e-0417272436a96714a0eb6ac438648135336c9791881ddadb
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 TGFBR3 PCARE ZNF804A

1.73e-041727246c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 TGFBR3 PCARE ZNF804A

1.73e-04172724381ae1c3c07d0a424f43455ec571653b192a946a
ToppCellCOPD-Lymphoid-ILC_A|Lymphoid / Disease state, Lineage and Cell class

ILDR2 BAZ2B CTDP1 GAS7

1.77e-041737244a0043b29f8ede5a74bdb38cbf2c70e12b25e130
ToppCellfacs-GAT-Fat-18m|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELOB CDX1 CDHR5 SF3A2

1.77e-04173724515cb02f3eef86a1ff9a2b4b4f794373ed6633aa
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

AFF2 MAP1B KALRN RUNX1T1

1.77e-041737245416b092321c7d9b63f0418c60f2402a138355bf
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 TGFBR3 PCARE ZNF804A

1.81e-04174724dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGFBR3 DTNA HECTD4 GAS7

1.85e-041757241d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGFBR3 DTNA HECTD4 GAS7

1.85e-04175724427a7ee92fe16a90625946492062d37aa0f7235b
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B KALRN SHC1 GAS7

1.93e-04177724227d4f423b00be2e0c5797e2c5275d342e69a0f4
ToppCellmetastatic_Lymph_Node-Endothelial_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

JCAD KALRN ASXL3 RUNX1T1

1.93e-0417772471bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B KALRN SHC1 GAS7

1.93e-0417772466ffa279147961080c104242a08b176e301d80e3
ToppCellfacs-Thymus-Epithelium-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAS7 ARHGAP17 IRS2 FHIP1A

1.93e-041777240e9e44119653abfd270e602e5e477a15e774638f
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B KALRN SHC1 GAS7

1.93e-041777240cbf54608d2ba0a0500af142f2029fe5e118c3c2
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAS7 ARHGAP17 IRS2 FHIP1A

1.93e-04177724c2b8a3a149d70f77612759dea34df9e43953c566
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAS7 ARHGAP17 IRS2 FHIP1A

1.93e-04177724384f841aa7b2d05815af7885e481f5affc55d897
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TGFBR3 LRRIQ1 ZMIZ1 RUNX1T1

2.02e-04179724747a32460b257fffca30527b56a74720eb9c12e4
ToppCellILEUM-non-inflamed-(7)_Lymphatics|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

JCAD TGFBR3 KALRN SHC1

2.02e-0417972499777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFB2 DTNA GAS7 SRCIN1

2.15e-04182724d6740bca2b974122b8451989365a94a81140afd1
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ILDR2 JCAD TGFBR3 KALRN

2.15e-04182724a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TGFBR3 MAP1B GAS7 RUNX1T1

2.15e-04182724812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

ILDR2 TGFBR3 MAP1B ZNF804A

2.20e-04183724fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCellwk_08-11-Epithelial-PNS-COL20A1+_Schwann|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GAS7 SRCIN1 ITIH6 ZNF804A

2.29e-04185724abec2a49fe0f0fa4cba49347207a1ee317333657
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TGFB2 TGFBR3 DTNA RUNX1T1

2.29e-041857246712512100ccef456d2e2bd201d0987986c92ac9
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD MAP1B ESR1 IRS2

2.29e-04185724eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCellControl-Lymphoid-ILC_A|Lymphoid / Disease state, Lineage and Cell class

ILDR2 CTDP1 GAS7 RERE

2.29e-04185724520795866d44def5be3910ce8e728045c716a24d
ToppCellEndothelial-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

TGFB2 MAP1B KALRN SHC1

2.29e-04185724133c9dc64d564dae4aeeeca22f386aa3f13fa980
ToppCellCiliated_cells-A-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

ERICH3 LRRIQ1 MAP1B ASXL3

2.29e-04185724d77ca57b02125a3a57a37f4aed20c89803b7d551
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AFF2 PCARE ZNF804A SDK1

2.34e-04186724948815663c212c4311329d503b5991cbbbff9808
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRRIQ1 KALRN ASXL3 DENND3

2.34e-0418672484ba666237c18189d7e7556bd92dd953af733c00
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAP1B KALRN DTNA SDK1

2.34e-041867244780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 TGFBR3 MAP1B PCARE

2.34e-041867241094c7140131454b2583200e1c01e81ccab3db23
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFBR3 MAP1B KALRN SHC1

2.34e-0418672440070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

HECTD4 RERE ARID1A SDK1

2.34e-04186724de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

HECTD4 RERE ARID1A SDK1

2.34e-041867240b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

DTNA ASXL3 RUNX1T1 SDK1

2.38e-04187724e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B KALRN SHC1 GAS7

2.38e-0418772465d406122dffe18279f14a1ed35ba091730b97be
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

MAP1B KALRN DTNA SDK1

2.38e-04187724464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B KALRN SHC1 GAS7

2.38e-041877244c15c0ed41a55271fc793cb76fee97fa64190369
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAP1B KALRN ESR1 SDK1

2.38e-0418772476bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B KALRN SHC1 GAS7

2.38e-041877245274f2b302bbf7fed30c480af4f35058d2cf61e0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 TGFBR3 MAP1B PCARE

2.43e-041887249db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

TGFBR3 ESR1 GAS7 RUNX1T1

2.43e-04188724706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TGFB2 TGFBR3 RUNX1T1 SDK1

2.43e-041887240e2d1b21f0a7ee306e7dae16fc8c19d16a467883
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 TGFBR3 MAP1B PCARE

2.43e-04188724047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

TGFBR3 TCF7L2 GAS7 RUNX1T1

2.48e-041897240c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCellNeuroendocrine-neuroendo-2-Calca|World / Class top

MAP1B ASXL3 PODXL2 RUNX1T1

2.48e-041897246baa9a74560121cc008bb8fa9b2b7a335b3aeee0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 MAP1B KALRN GAS7

2.53e-04190724876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B KALRN RUNX1T1 FAM186B

2.53e-041907241121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 MAP1B KALRN GAS7

2.53e-04190724be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B KALRN RUNX1T1 FAM186B

2.53e-04190724048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 MAP1B KALRN GAS7

2.53e-0419072409a8855901c3c9332dbaab3e40166485b696d0f1
ToppCell(2)_Fibroblasts-(21)_Fibro-2|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

ILDR2 PODXL2 CDHR5 SDK1

2.53e-04190724d2afa08ad868acc6fce308ec21b0bf93591d4010
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HIVEP3 GAS7 RUNX1T1 SDK1

2.53e-0419072445df8fee00f8949937863159d7aa042e72748d9b
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TGFB2 JCAD TGFBR3 KALRN

2.53e-041907240e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ILDR2 JCAD TGFBR3 KALRN

2.58e-04191724f229abf69a1217194f74b0502486907e07dba989
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 JCAD TGFBR3 KALRN

2.58e-04191724f663131a4810584c5854bd64ee7991a237b7707f
ToppCellControl-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

MAP1B KALRN DTNA DENND3

2.58e-041917242da83c493e60ad0278848957645277d76737a188
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DTNA GAS7 RUNX1T1 SDK1

2.58e-04191724b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HIVEP3 KALRN GAS7 SDK1

2.58e-0419172408720998aa55131d7377c4c67c4c935865bd7d79
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B KALRN ARHGAP17 RUNX1T1

2.58e-041917247b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B KALRN ARHGAP17 RUNX1T1

2.58e-04191724cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCell3'-Child09-12-SmallIntestine-Neuronal-Glial_mature|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFB2 MAP1B DTNA GAS7

2.64e-04192724ac507fd7cf3b3e521a15ef03bb4e81eb23807985
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

PHF3 RERE ZFC3H1 SDK1

2.64e-04192724916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell3'-Child09-12-SmallIntestine-Neuronal|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFB2 MAP1B DTNA GAS7

2.64e-0419272424f40dadec04f4f99c31000fa9f09d07148fa190
ToppCellEndothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|World / Lineage, Cell type, age group and donor

ILDR2 JCAD TGFBR3 KALRN

2.64e-041927241e156bab5ecf64627890d2de9b27603d9a01f28d
ToppCell3'-Child09-12-SmallIntestine-Neuronal-Glial_mature-Adult_Glia|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFB2 MAP1B DTNA GAS7

2.64e-0419272471e04e197825856c6d4278fc76c58ab17ffa2387
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB2 TGFBR3 AFF2 IRS2

2.64e-0419272411088878043a6ff95ba1970361256a82e434b80a
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DTNA GAS7 RUNX1T1 SDK1

2.64e-04192724deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DTNA ASXL3 RUNX1T1 SDK1

2.69e-04193724fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ERICH3 LRRIQ1 MAP1B AK9

2.69e-041937240b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellLA|World / Chamber and Cluster_Paper

TGFBR3 MAP1B GAS7 SDK1

2.69e-04193724d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellLAM-Endothelial-LymEndo|LAM / Condition, Lineage and Cell class

JCAD MAP1B KALRN SHC1

2.69e-0419372468eadc91c2d89edd2412e86dfe134dd7c0ef6ee9
DrugWithaferin A [5119-48-2]; Down 200; 1uM; MCF7; HT_HG-U133A

TGFB2 HIVEP3 TCF7L2 FAM120C ESR1 GAS7 RERE ZNF804A CDK10

5.65e-091867093902_DN
DrugGabazine [105538-73-6]; Down 200; 10.8uM; PC3; HT_HG-U133A

TCF7L2 FAM120C DTNA MINK1 CDK10 SF3A2 DENND3 PLXNB1

1.56e-071967084236_DN
DrugGraveoline [485-61-0]; Down 200; 14.4uM; PC3; HT_HG-U133A

HIVEP3 FAM120C BICRA MINK1 CTDP1 RERE CDK10 PLXNB1

1.56e-071967084276_DN
DrugTolbutamide [64-77-7]; Down 200; 14.8uM; MCF7; HT_HG-U133A

TCF7L2 DTNA ESR1 CTDP1 IRS2 RERE ARID1A

1.94e-061907074362_DN
DrugCimetidine [51481-61-9]; Down 200; 15.8uM; MCF7; HT_HG-U133A

TGFB2 PHF3 BICRA ESR1 CTDP1 IRS2 RERE

2.15e-061937071464_DN
DrugMetolazone [17560-51-9]; Down 200; 11uM; MCF7; HT_HG-U133A

TCF7L2 DTNA ESR1 MINK1 GAS7 ARID1A SF3A2

2.31e-061957071514_DN
DrugZomepirac sodium salt [64092-48-4]; Up 200; 12.8uM; PC3; HT_HG-U133A

AFF2 CLCN7 PHF3 DTNA MINK1 GAS7 RUNX1T1

2.39e-061967074479_UP
DrugMepenzolate bromide [76-90-4]; Down 200; 9.6uM; PC3; HT_HG-U133A

HIVEP3 JCAD CLCN7 FAM120C GAS7 PODXL2 ARID1A

2.47e-061977073748_DN
Drug(+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Down 200; 11uM; PC3; HT_HG-U133A

JCAD CLCN7 SF3A1 MINK1 GAS7 ARID1A PLXNB1

2.47e-061977076663_DN
DrugMinoxidil [38304-91-5]; Down 200; 19.2uM; MCF7; HT_HG-U133A

HIVEP3 TCF7L2 FAM120C PHF3 BICRA CEP170B PLXNB1

2.55e-061987074800_DN
Drugarachidonic acid sodium salt; Up 200; 10uM; MCF7; HG-U133A

TGFB2 ELOB DTNA BICRA ESR1 CTDP1 RERE

2.55e-06198707443_UP
DrugMethylatropine nitrate [52-88-0]; Down 200; 11uM; MCF7; HT_HG-U133A

HIVEP3 FAM120C PHF3 ESR1 ZNF804A CLEC16A CDK10

2.64e-061997076495_DN
DrugAztreonam [78110-38-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A

TGFB2 HIVEP3 JCAD DTNA ESR1 IRS2 CDK10

2.73e-062007075535_UP
Drugisoprunetin 7-O-beta-D-glucopyranoside

GLB1 ESR1

9.32e-062702CID000189922
Drugo,p'-dicofol

GLB1 ESR1

9.32e-062702CID000091566
Drug2-chloro-4-nonylphenol

GLB1 ESR1

9.32e-062702CID000043176
DrugRifabutin [72559-06-9]; Down 200; 4.8uM; MCF7; HT_HG-U133A

DTNA ESR1 ARID1A CDK10 SF3A2 PLXNB1

2.19e-051847064349_DN
DrugMepenzolate bromide [76-90-4]; Up 200; 9.6uM; PC3; HT_HG-U133A

TGFB2 KALRN PHF3 DTNA SF3A1 MINK1

2.55e-051897064304_UP
DrugBupivacaine hydrochloride [18010-40-7]; Down 200; 12.4uM; MCF7; HT_HG-U133A

GATAD2A DAZAP1 MAP1B DTNA ESR1 CDK10

2.70e-051917067435_DN
DrugAcetohexamide [968-81-0]; Up 200; 12.4uM; PC3; HT_HG-U133A

HNRNPDL CDX1 CLCN7 ESR1 MINK1 ARID1A

2.79e-051927061829_UP
Druglicoflavone

GLB1 ESR1

2.79e-053702CID005319000
DrugSTOCK1N-28457; Down 200; 20uM; MCF7; HT_HG-U133A

HIVEP3 TCF7L2 DTNA ESR1 MINK1 GAS7

2.87e-051937066869_DN
DrugOxymetazoline hydrochloride [2315-02-8]; Down 200; 13.4uM; PC3; HT_HG-U133A

TGFBR3 CLCN7 PHF3 ESR1 CTDP1 CDK10

2.87e-051937062114_DN
DrugCarbarsone [121-59-5]; Up 200; 15.4uM; MCF7; HT_HG-U133A

TGFBR3 CLCN7 PHF3 ESR1 MINK1 RERE

2.87e-051937063250_UP
Drug(d,l)-Tetrahydroberberine [522-97-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A

TGFB2 AFF2 CLCN7 ESR1 PODXL2 RUNX1T1

2.87e-051937064138_DN
DrugHycanthone [3105-97-3]; Down 200; 11.2uM; MCF7; HT_HG-U133A

TCF7L2 MAP1B DTNA ESR1 PODXL2 NUP160

2.87e-051937063229_DN
DrugY-27632; Up 200; 3uM; MCF7; HT_HG-U133A_EA

TGFB2 MAP1B DTNA BICRA CTDP1 GAS7

2.87e-05193706948_UP
DrugButoconazole nitrate [32872-77-1]; Down 200; 8.4uM; HL60; HT_HG-U133A

ELOB TCF7L2 PIAS3 DTNA ESR1 CEP170B

2.95e-051947062427_DN
DrugPimozide [2062-78-4]; Up 200; 8.6uM; PC3; HT_HG-U133A

DTNA ESR1 CTDP1 IRS2 DENND3 PLXNB1

2.95e-051947067132_UP
DrugChicago sky blue 6B [2610-05-1]; Up 200; 4uM; PC3; HT_HG-U133A

TGFB2 PHF3 DTNA GAS7 RUNX1T1 ARID1A

3.04e-051957066626_UP
DrugCarbimazole [22232-54-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A

TGFBR3 FAM120C DTNA CTDP1 IRS2 ZNF804A

3.04e-051957065399_DN
Drugcox-2 inhibitor I; Up 200; 10uM; MCF7; HG-U133A

AFF2 CLCN7 DTNA ESR1 DENND3 PLXNB1

3.04e-05195706207_UP
DrugMephenytoin [50-12-4]; Down 200; 18.4uM; MCF7; HT_HG-U133A

HIVEP3 MAP1B GAS7 IRS2 CDK10 PLXNB1

3.04e-051957063580_DN
DrugSulfapyridine [144-83-2]; Down 200; 16uM; MCF7; HT_HG-U133A

TGFB2 TGFBR3 CLCN7 DTNA GAS7 IRS2

3.04e-051957066101_DN
DrugBrinzolamide [138890-62-7]; Down 200; 10.4uM; PC3; HT_HG-U133A

TGFB2 SF3A1 GAS7 IRS2 ARID1A PLXNB1

3.04e-051957066670_DN
DrugBenzbromarone [3562-84-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A

TGFB2 TCF7L2 CLCN7 MINK1 CTDP1 IRS2

3.13e-051967065015_DN
DrugAminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; PC3; HT_HG-U133A

FAM120C DTNA MINK1 PODXL2 RERE CDK10

3.13e-051967063726_DN
DrugCotinine (-) [486-56-6]; Down 200; 22.6uM; MCF7; HT_HG-U133A

MAP1B DTNA ESR1 MINK1 GAS7 ARID1A

3.13e-051967061511_DN
DrugTranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; PC3; HT_HG-U133A

JCAD TCF7L2 PHF3 DTNA ARID1A NUP160

3.13e-051967062101_UP
DrugOxantel pamoate [68813-55-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A

TCF7L2 CLCN7 MAP1B FAM120C ESR1 ARHGAP17

3.13e-051967065338_UP
DrugDiflorasone Diacetate [33564-31-7]; Down 200; 8uM; MCF7; HT_HG-U133A

CTDP1 ARHGAP17 IRS2 CDK10 CEP170B MAP3K4

3.22e-051977064158_DN
Drug15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A

HIVEP3 ESR1 CTDP1 GAS7 RUNX1T1 SF3A2

3.22e-051977067521_UP
DrugGlipizide [29094-61-9]; Down 200; 9uM; MCF7; HT_HG-U133A

MAP1B DTNA MINK1 CTDP1 GAS7 IRS2

3.22e-051977061508_DN
DrugNorgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A

TGFB2 AFF2 ESR1 MINK1 GAS7 RERE

3.22e-051977064730_DN
Drugrosiglitazone; Down 200; 10uM; MCF7; HT_HG-U133A_EA

TCF7L2 ESR1 CTDP1 PODXL2 IRS2 SF3A2

3.22e-051977061013_DN
DrugSulfadiazine [68-35-9]; Down 200; 16uM; PC3; HT_HG-U133A

TCF7L2 CLCN7 BICRA NUP160 CEP170B DENND3

3.22e-051977061810_DN
DrugNorethindrone [68-22-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A

TCF7L2 DTNA ESR1 CDK10 SF3A2 NUP160

3.22e-051977067414_DN
DrugNU1025; Up 200; 100uM; MCF7; HG-U133A

HIVEP3 ELOB CLCN7 PHF3 GAS7 DENND3

3.22e-05197706313_UP
Drugaspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A

TGFB2 GATAD2A FAM120C DTNA PODXL2 CDK10

3.22e-051977065564_DN
DrugNifuroxazide [965-52-6]; Up 200; 14.6uM; HL60; HT_HG-U133A

AFF2 ESR1 MINK1 RERE ARID1A CEP170B

3.22e-051977062490_UP
DrugCloperastine hydrochloride [14984-68-0]; Down 200; 11uM; HL60; HT_HG-U133A

HIVEP3 TCF7L2 PHF3 DTNA ESR1 CDK10

3.31e-051987062549_DN
DrugTetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; HL60; HT_HG-U133A

ELOB TCF7L2 BICRA GAS7 RERE CDK10

3.31e-051987062489_DN
DrugCephapirin sodium salt [24356-60-3]; Down 200; 9uM; HL60; HT_HG-U133A

TCF7L2 FAM120C PHF3 DTNA MINK1 RERE

3.31e-051987062730_DN
DrugChlorhexidine [55-56-1]; Down 200; 8uM; MCF7; HT_HG-U133A

TCF7L2 CLCN7 PHF3 DTNA GAS7 ARID1A

3.31e-051987061525_DN
DrugBoldine [476-70-0]; Down 200; 12.2uM; PC3; HT_HG-U133A

CLCN7 MAP1B DTNA BICRA CTDP1 GAS7

3.31e-051987064004_DN
DrugThiocolchicoside [602-41-5]; Up 200; 7uM; MCF7; HT_HG-U133A

TGFB2 AFF2 ESR1 CTDP1 IRS2 CDK10

3.31e-051987065520_UP
DrugTocainide hydrochloride; Down 200; 17.4uM; MCF7; HT_HG-U133A

TCF7L2 MAP1B FAM120C BICRA ESR1 ARID1A

3.31e-051987064838_DN
Drugnordihydroguaiaretic acid; Down 200; 1uM; MCF7; HT_HG-U133A

HNRNPDL TCF7L2 BICRA MINK1 SF3A2 NUP160

3.40e-051997066942_DN
DrugDacarbazine [4342-03-4]; Down 200; 22uM; MCF7; HT_HG-U133A

CLCN7 BAZ2B BICRA ESR1 CDK10 SF3A2

3.40e-051997062754_DN
DrugTHIP Hydrochloride; Down 200; 22.6uM; MCF7; HT_HG-U133A

TCF7L2 CLCN7 PHF3 ESR1 IRS2 CDK10

3.40e-051997066511_DN
Drugchlorpromazine hydrochloride; Down 200; 1uM; MCF7; HT_HG-U133A_EA

GATAD2A ESR1 PODXL2 IRS2 CLEC16A SF3A2

3.40e-05199706997_DN
DrugLevamisole hydrochloride [16595-80-5]; Down 200; 16.6uM; MCF7; HT_HG-U133A

HIVEP3 DTNA ESR1 MINK1 GAS7 SF3A2

3.40e-051997062257_DN
DrugClozapine [5786-21-0]; Down 200; 12.2uM; PC3; HT_HG-U133A

TGFB2 JCAD DTNA ESR1 CDK10 NUP160

3.40e-051997064670_DN
DrugMebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Down 200; 4.8uM; PC3; HT_HG-U133A

KALRN DTNA ESR1 MINK1 SF3A2 PLXNB1

3.40e-051997064211_DN
DrugVerapamyl hydrochloride [152-11-4]; Down 200; 8.2uM; MCF7; HT_HG-U133A

TCF7L2 ESR1 CTDP1 GAS7 IRS2 PLXNB1

3.40e-051997061509_DN
Druggenistein; Down 200; 1uM; MCF7; HG-U133A

CLCN7 ESR1 MINK1 GAS7 SF3A2 PLXNB1

3.40e-05199706267_DN
DrugMeropenem [96036-03-2]; Down 200; 10.4uM; MCF7; HT_HG-U133A

TGFB2 MAP1B PHF3 GAS7 CDK10 SF3A2

3.40e-051997063564_DN
DrugDibucaine [85-79-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A

TCF7L2 CLCN7 PHF3 ESR1 CTDP1 IRS2

3.40e-051997061469_DN
DrugEstriol [50-27-1]; Down 200; 13.8uM; MCF7; HT_HG-U133A

TGFB2 IRS2 ZNF804A CDK10 SF3A2 PLXNB1

3.40e-051997063563_DN
DrugFlucytosine [2022-85-7]; Down 200; 31uM; PC3; HT_HG-U133A

HIVEP3 PHF3 MINK1 PODXL2 SF3A2 NUP160

3.50e-052007066690_DN
Drug2-(ethylsulfonyl)ethanol

AFF2 DAZAP1 GLB1 SF3A1 RERE SF3A2

4.60e-05210706CID000010549
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

TGFB2 HIVEP3 ESR1 ARID1A CDK10

1.65e-041677053979_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

BAZ2B ESR1 ZMIZ1 ARID1A MAP3K4

1.89e-041727057179_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

TCF7L2 ESR1 ARID1A CDK10 SF3A2

2.22e-041787054710_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

ESR1 ZMIZ1 ARID1A NUP160 MAP3K4

2.27e-041797055484_DN
Drugtrichostatin A; Down 200; 0.1uM; MCF7; HG-U133A

TGFB2 ESR1 ZMIZ1 ARID1A NUP160

2.27e-04179705331_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

TGFB2 ESR1 ZMIZ1 ARID1A SF3A2

2.33e-041807055511_DN
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; PC3; HT_HG-U133A

TCF7L2 PHF3 ZMIZ1 ARID1A MAP3K4

2.33e-041807054541_DN
DrugLY 294002; Up 200; 10uM; PC3; HT_HG-U133A

TCF7L2 PHF3 IRS2 ARID1A CEP170B

2.39e-041817051236_UP
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA

ESR1 IRS2 ZFC3H1 CDK10 SF3A2

2.46e-04182705947_DN
Drugmyrtenal

GLB1 IRS2

2.58e-048702ctd:C061545
DrugLY 294002; Up 200; 10uM; MCF7; HT_HG-U133A

TCF7L2 BAZ2B ESR1 GAS7 IRS2

2.71e-041867056987_UP
Drugchlorpromazine hydrochloride; Down 200; 1uM; MCF7; HT_HG-U133A

PHF3 DTNA MINK1 CTDP1 PODXL2

3.07e-041917055214_DN
DrugDimethisoquin hydrochloride [2773-92-4]; Up 200; 13uM; MCF7; HT_HG-U133A

TGFB2 TCF7L2 DTNA ESR1 IRS2

3.07e-041917054791_UP
DrugAstemizole [68844-77-9]; Down 200; 8.8uM; PC3; HT_HG-U133A

TGFBR3 TCF7L2 DTNA ESR1 SF3A2

3.07e-041917054471_DN
DrugGabexate mesilate [56974-61-9]; Down 200; 9.6uM; HL60; HT_HG-U133A

HIVEP3 PIAS3 ESR1 MINK1 RERE

3.07e-041917052937_DN
DrugLabetalol hydrochloride [32780-64-6]; Down 200; 11uM; MCF7; HT_HG-U133A

CLCN7 DTNA ESR1 CTDP1 SF3A2

3.14e-041927056809_DN
DrugPyrantel tartrate [33401-94-4]; Down 200; 11.2uM; HL60; HG-U133A

GATAD2A CLCN7 MINK1 ARID1A SF3A2

3.14e-041927051413_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A

HIVEP3 TCF7L2 ARID1A ZNF804A CEP170B

3.14e-041927052450_DN
DrugProguanil hydrochloride [637-32-1]; Down 200; 13.8uM; MCF7; HT_HG-U133A

TGFB2 TCF7L2 MINK1 CDK10 PLXNB1

3.14e-041927053505_DN
DrugResveratrol [501-36-0]; Down 200; 17.6uM; MCF7; HT_HG-U133A

TGFB2 PHF3 DTNA BICRA ESR1

3.14e-041927052865_DN
DrugButylparaben [94-26-8]; Down 200; 20.6uM; MCF7; HT_HG-U133A

TGFBR3 TCF7L2 ESR1 MINK1 GAS7

3.22e-041937055608_DN
DrugFlumethasone [2135-17-3]; Down 200; 9.8uM; PC3; HT_HG-U133A

HIVEP3 CLCN7 GAS7 PODXL2 SF3A2

3.22e-041937053712_DN
DrugTriamcinolone [124-94-7]; Up 200; 10.2uM; PC3; HT_HG-U133A

MINK1 PODXL2 IRS2 SF3A2 DENND3

3.22e-041937052078_UP
DrugDiethylstilbestrol [56-53-1]; Down 200; 15uM; HL60; HT_HG-U133A

TCF7L2 CLCN7 PHF3 BICRA ESR1

3.22e-041937052567_DN
DrugRapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A

CLCN7 FAM120C DTNA ESR1 PODXL2

3.22e-041937056981_UP
DrugProgesterone [57-83-0]; Down 200; 12.8uM; PC3; HT_HG-U133A

BICRA RERE ARID1A SF3A2 DENND3

3.22e-041937056646_DN
DrugNifuroxazide [965-52-6]; Down 200; 14.6uM; PC3; HT_HG-U133A

HIVEP3 AFF2 DTNA CLEC16A PLXNB1

3.22e-041937054253_DN
DrugSulfacetamide sodic hydrate [6209-17-2]; Up 200; 15.8uM; PC3; HT_HG-U133A

HIVEP3 GATAD2A CLCN7 MAP1B IRS2

3.22e-041937051817_UP
DrugEucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A

PHF3 DTNA ESR1 RERE CDK10

3.22e-041937053841_DN
DiseaseNeurodevelopmental Disorders

HIVEP3 KMT2C TCF7L2 ASXL3 PLXNB1

2.67e-0693695C1535926
Diseaseattention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia

TCF7L2 RERE ZMIZ1 ZNF804A CDK10

4.02e-06101695EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
DiseaseColorectal Carcinoma

HIVEP3 KMT2C TCF7L2 MAP1B KALRN SF3A1 ZMIZ1 RUNX1T1 ARID1A ZNF804A

5.23e-067026910C0009402
DiseaseKlatskin's tumor (is_implicated_in)

KMT2C ARID1A

5.36e-055692DOID:4927 (is_implicated_in)
Diseaseneutrophil percentage of leukocytes

KALRN BAZ2B MINK1 RERE ZMIZ1 ARID1A CLEC16A NUP160

8.79e-05610698EFO_0007990
Diseaseschizophrenia, type 2 diabetes mellitus

TCF7L2 GATAD2A RUNX1T1

1.41e-0443693MONDO_0005090, MONDO_0005148
Diseasealcohol use disorder measurement

JCAD TCF7L2 HECTD4 RUNX1T1 ZNF804A

1.48e-04214695EFO_0009458
Diseasebody weight

TGFB2 TCF7L2 PHF3 ASXL3 ESR1 HECTD4 SPATA31C2 RUNX1T1 ITIH6 CDK10 NUP160

1.55e-0412616911EFO_0004338
DiseaseCarcinoma, Granular Cell

KMT2C TCF7L2 ESR1 ARID1A

1.61e-04116694C0205644
DiseaseAdenocarcinoma, Tubular

KMT2C TCF7L2 ESR1 ARID1A

1.61e-04116694C0205645
DiseaseAdenocarcinoma, Oxyphilic

KMT2C TCF7L2 ESR1 ARID1A

1.61e-04116694C0205642
DiseaseCarcinoma, Cribriform

KMT2C TCF7L2 ESR1 ARID1A

1.61e-04116694C0205643
DiseaseAdenocarcinoma, Basal Cell

KMT2C TCF7L2 ESR1 ARID1A

1.61e-04116694C0205641
DiseaseAdenocarcinoma

KMT2C TCF7L2 ESR1 ARID1A

1.61e-04116694C0001418
Diseaseintraocular pressure measurement

TGFB2 HIVEP3 JCAD TCF7L2 KALRN GAS7 NUP160

1.87e-04509697EFO_0004695
Diseaseloneliness measurement

TCF7L2 RERE ZNF804A NUP160

2.08e-04124694EFO_0007865
Diseasewellbeing measurement

TCF7L2 BAZ2B ASXL3 NAF1 RERE ZNF804A SDK1 NUP160

2.08e-04692698EFO_0007869
Diseasefree androgen index

TGFB2 TCF7L2 ESR1 ZMIZ1 ARID1A NUP160

2.44e-04374696EFO_0007005
Diseasebasophil count, eosinophil count

HIVEP3 ELOB GLB1 RERE CLEC16A

2.56e-04241695EFO_0004842, EFO_0005090
DiseaseEndometrial Neoplasms

ESR1 ARID1A MAP3K4

3.44e-0458693C0014170
Diseasepulse pressure measurement

HIVEP3 JCAD TGFBR3 TCF7L2 GATAD2A DAZAP1 MAP1B ESR1 FAM186B CLEC16A NUP160

3.64e-0413926911EFO_0005763
Diseaseunipolar depression

JCAD TCF7L2 ASXL3 ESR1 PCARE AK9 LYSMD4 RERE ZNF804A SDK1

4.75e-0412066910EFO_0003761
DiseaseCoronary Arteriosclerosis

JCAD ESR1 HECTD4

4.82e-0465693C0010054
DiseaseCoronary Artery Disease

JCAD ESR1 HECTD4

4.82e-0465693C1956346
Diseasedepressive symptom measurement

TCF7L2 ASXL3 RERE ZNF804A SDK1 NUP160

4.87e-04426696EFO_0007006
Diseaseacute graft vs. host disease, donor genotype effect measurement

KALRN SDK1

5.55e-0415692EFO_0004599, EFO_0007892
DiseaseT-Cell Lymphoma

ASXL3 ARID1A

6.33e-0416692C0079772
Diseasepancreatitis

JCAD HECTD4

6.33e-0416692EFO_0000278
DiseaseEndometrial Carcinoma

ESR1 ARID1A MAP3K4

6.50e-0472693C0476089
Diseasecorneal resistance factor

TGFB2 TGFBR3 TCF7L2 FBXO31 ESR1 GAS7

6.56e-04451696EFO_0010067
DiseaseTourette syndrome, schizophrenia

PHF3 RERE

8.05e-0418692EFO_0004895, MONDO_0005090
Diseaseage of onset of asthma

GLB1 RERE CLEC16A

8.52e-0479693OBA_2001001
Diseaseneuroticism measurement, wellbeing measurement, depressive symptom measurement

TCF7L2 SDK1

8.98e-0419692EFO_0007006, EFO_0007660, EFO_0007869
Diseasemonocyte count

HIVEP3 JCAD TGFBR3 TCF7L2 AFF2 KALRN BAZ2B CTDP1 IRS2 ZMIZ1

9.53e-0413206910EFO_0005091
Diseaseosteoporosis (biomarker_via_orthology)

ESR1 IRS2

1.21e-0322692DOID:11476 (biomarker_via_orthology)
Diseasesensory peripheral neuropathy, remission

GAS7 RUNX1T1

1.32e-0323692EFO_0009785, MONDO_0002321
DiseaseIntrahepatic Cholangiocarcinoma

KMT2C ARID1A

1.44e-0324692C0345905
DiseaseExtrahepatic Cholangiocarcinoma

KMT2C ARID1A

1.44e-0324692C3805278
DiseaseInhalant adrenergic use measurement

GLB1 RERE CLEC16A

1.50e-0396693EFO_0009941
Diseasealcohol use disorder measurement, alcohol consumption measurement

TCF7L2 RUNX1T1 NUP160

1.54e-0397693EFO_0007878, EFO_0009458
Diseaseunipolar depression, schizophrenia

TCF7L2 ZNF804A

1.56e-0325692EFO_0003761, MONDO_0005090
Diseaseobesity (implicated_via_orthology)

TCF7L2 ESR1 SDK1 PLXNB1

1.64e-03215694DOID:9970 (implicated_via_orthology)
Diseaseplatelet crit

JCAD GATAD2A KALRN IRS2 RERE ARID1A FHIP1A NUP160

1.67e-03952698EFO_0007985
DiseaseAntiglaucoma preparations and miotics use measurement

GAS7 NUP160

1.69e-0326692EFO_0009944
DiseaseCholangiocarcinoma

KMT2C ARID1A

1.69e-0326692C0206698
Diseaseneurotic disorder

ASXL3 RERE ZNF804A

1.73e-03101693EFO_0004257
DiseaseBone Diseases, Developmental

TGFB2 GLB1

1.82e-0327692C0005941
DiseaseSezary Syndrome

KMT2C ARID1A

1.82e-0327692C0036920
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

TCF7L2 AFF2 IRS2

1.93e-03105693DOID:9352 (implicated_via_orthology)
DiseaseTYPE 2 DIABETES MELLITUS

TCF7L2 IRS2

1.96e-0328692125853
DiseaseType 2 diabetes mellitus

TCF7L2 IRS2

1.96e-0328692cv:C0011860
Diseaseneutrophil percentage of granulocytes

HIVEP3 GLB1 RERE CLEC16A

2.03e-03228694EFO_0007994
Diseaseage at first sexual intercourse measurement

TCF7L2 ESR1 RUNX1T1 ZNF804A SDK1

2.04e-03383695EFO_0009749
Diseaselymphocyte count

JCAD TCF7L2 KALRN MINK1 HECTD4 RERE ZMIZ1 CLEC16A NUP160 DENND3

2.06e-0314646910EFO_0004587
Diseaseneuroticism measurement, cognitive function measurement

TCF7L2 KALRN ASXL3 RERE ARID1A ZNF804A

2.09e-03566696EFO_0007660, EFO_0008354
DiseaseBilateral Wilms Tumor

ARID1A MAP3K4

2.10e-0329692C2930471
Diseaseeosinophil percentage of granulocytes

HIVEP3 GLB1 RERE CLEC16A

2.23e-03234694EFO_0007996
Diseaseopioid dependence

MAP1B CTDP1 ARHGAP17 SRCIN1

2.33e-03237694EFO_0005611

Protein segments in the cluster

PeptideGeneStartEntry
PPTALFHPMPVLPKA

CTDP1

751

Q9Y5B0
FHPMPVLPKAQPGPE

CTDP1

756

Q9Y5B0
NMPILSPHPPVGPKS

ERICH3

116

Q5RHP9
QPPQPPMAHDITATP

CDX1

221

P47902
PVDFPSPKPIPEEMQ

BAZ2B

1701

Q9UIF8
HPSAPMPPPSVVILN

AFF2

131

P51816
PMKEEQLFSPLPPSP

FAM186B

361

Q8IYM0
PSQPPEVPAHEMPTK

CEP170B

236

Q9Y4F5
SPTHDPKPAEAPMPA

CDHR5

731

Q9HBB8
PSPPPGPLHLVFNMK

DENND3

156

A2RUS2
APDMSKPPTAQPDFP

DAZAP1

331

Q96EP5
AHTMPNKALVHPPPP

ASXL3

2006

Q9C0F0
KLKHQMAEPLPPEPP

GOLGA8F;

81

Q08AF8
MEVPPRLSHVPPPLF

HNRNPDL

1

O14979
MEPKPDPFPQESPLD

NOBOX

396

O60393
PASHIAPAPVQPPMI

ARID1A

1621

O14497
PKPPAPEMNFLPSAA

GATAD2A

366

Q86YP4
LPKMNLVEPPWHMPP

PODXL2

146

Q9NZ53
LQPPMPKPLSPLHSL

NOL9

531

Q5SY16
PPDTPRPVMTDQFPK

KMT2C

1966

Q8NEZ4
KHMDPPPAPVQDRSP

MAP1B

2196

P46821
SHQPLLPAPPKTPMD

LYSMD4

196

Q5XG99
HPTPPPPQHYRLDDM

RUNX1T1

291

Q06455
IPIPLNERHSPKMPP

JCAD

246

Q9P266
DHPSKPVEKRLMPPP

GLB1

651

P16278
PDMDPPHPFPKEIPH

CLCN7

71

P51798
PPHDPHVDDPMRFKP

FBXO31

176

Q5XUX0
QPLNPEDPTMPFRHK

PLXNB1

1381

O43157
SPLMLLHPPPQLSPF

ESR1

106

P03372
PDEESHTPLPPPMKI

KALRN

1831

O60229
HTPLPPPMKIFDNDP

KALRN

1836

O60229
HVPPYPMKIAPPDGT

HECTD4

3936

Q9Y4D8
TPDFVPEPSPHDLPM

LRRIQ1

131

Q96JM4
LPSMHEYPLPPEPKS

IRS2

901

Q9Y4H2
GPPAPIDPPKHIQEM

FHIP1A

606

Q05DH4
EPFSSPPELPDVMKP

ELOB

91

Q15370
KPLPCEPELMPTFPH

CDK10

326

Q15131
NHMDITIPPLPPVAP

FAM120C

591

Q9NX05
PPAPAKPMHPENKLT

BCL9L

31

Q86UU0
LSKPETPNPHMPQTP

ITIH6

871

Q6UXX5
LHPMFPDQPEKPLNL

DTNA

316

Q9Y4J8
PPQPPGALSKPMSVH

BICRA

436

Q9NZM4
ARIMEKSTPHPPQPP

CCDC8

56

Q9H0W5
LMLPEEPPSAPPKNI

SDK1

761

Q7Z5N4
IPSPSPPMSPSQEHK

PCARE

1086

A6NGG8
PPMQRPVEPQEGPHK

MINK1

566

Q8N4C8
PMKVPRCHSDPPNPH

MAP3K4

1151

Q9Y6R4
YVPPLAPHPLPSADM

AK9

1691

Q5TCS8
KHPQDLASTPPPGPM

SPATA31C2

166

B4DYI2
PQPPTQATPLMHTKP

ARHGAP17

716

Q68EM7
FPHPDTMPEQQLLKP

GAS7

181

O60861
SMSHESPVLPPPQPL

SPATA31D4

536

Q6ZUB0
PFSMNANLPPPPALK

RERE

956

Q9P2R6
PPELDPLHPAANPME

RERE

1331

Q9P2R6
HPPPPMEDEPTSKKL

SF3A1

671

Q15459
MLHLSAAPPAPPPEV

NUP160

1

Q12769
HFKMEKPPAPPSLPA

SF3A2

211

Q15428
DAPMSPELPKPHLPD

CLEC16A

936

Q2KHT3
REVDMHPPLPQPVHP

PIAS3

111

Q9Y6X2
HPPLPQPVHPDVTMK

PIAS3

116

Q9Y6X2
IDMPPFFPSENAIPP

TGFB2

106

P61812
SMSHESPVLPPPQPL

SPATA31D3

536

P0C874
PKVQAADPAPPPTMF

SPEM2

431

Q0P670
KSVDFEMPPPSPPLN

SRCIN1

856

Q9C0H9
EMPPPSPPLNLHELS

SRCIN1

861

Q9C0H9
GMLMDKPHPPPLAPS

ILDR2

271

Q71H61
DPLAHLSMMPPPPAL

TCF7L2

541

Q9NQB0
PQHPLTPAFMSPGKP

HIVEP3

96

Q5T1R4
PFTQSRIPPDLPMHP

USP25

521

Q9UHP3
QSMFGFPPHLPPPLL

PHF3

1826

Q92576
SLFTMEPPHVPRKPP

TMEM201

566

Q5SNT2
PKEPFRSHPPSVRMP

ZFC3H1

106

O60293
MKPFEDALRVPPPPQ

SHC1

461

P29353
PSMKEPNPISPPIFH

TGFBR3

766

Q03167
VKPPFPPDIKPNMSA

ZMIZ1

536

Q9ULJ6
PPQMPIIPASVLHPS

ZNF804A

1166

Q7Z570
HQMAEPLPPEPPAVP

GOLGA8CP

281

A6NN73
LPVFDMHNFPLRPPP

NAF1

426

Q96HR8