Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	SR	SSC5D SSC4D CORIN DMBT1	4.43e-05	25	150	4	SM00202
Domain	SRCR-like_dom	SSC5D SSC4D CORIN DMBT1	5.21e-05	26	150	4	IPR017448
Domain	SRCR_1	SSC5D SSC4D CORIN DMBT1	5.21e-05	26	150	4	PS00420
Domain	SRCR_2	SSC5D SSC4D CORIN DMBT1	5.21e-05	26	150	4	PS50287
Domain	SRCR	SSC5D SSC4D CORIN DMBT1	6.07e-05	27	150	4	IPR001190
Domain	Gamma_tubulin	TUBG2 TUBG1	6.41e-05	2	150	2	IPR002454
Domain	C8	MUC5B SSPOP OTOG	1.06e-04	12	150	3	PF08742
Domain	TIL	MUC5B SSPOP OTOG	1.06e-04	12	150	3	PF01826
Domain	Unchr_dom_Cys-rich	MUC5B SSPOP OTOG	1.37e-04	13	150	3	IPR014853
Domain	C8	MUC5B SSPOP OTOG	1.37e-04	13	150	3	SM00832
Domain	ig	NPHS1 SEMA3F OBSCN OBSL1 SIRPG NECTIN2 FCRL5 BCAM	1.52e-04	190	150	8	PF00047
Domain	Immunoglobulin	NPHS1 SEMA3F OBSCN OBSL1 SIRPG NECTIN2 FCRL5 BCAM	1.52e-04	190	150	8	IPR013151
Domain	TIL_dom	MUC5B SSPOP OTOG	1.73e-04	14	150	3	IPR002919
Domain	VWF_type-D	MUC5B SSPOP OTOG	2.63e-04	16	150	3	IPR001846
Domain	VWFD	MUC5B SSPOP OTOG	2.63e-04	16	150	3	PS51233
Domain	VWD	MUC5B SSPOP OTOG	2.63e-04	16	150	3	SM00216
Domain	VWD	MUC5B SSPOP OTOG	2.63e-04	16	150	3	PF00094
Domain	VWC_out	MUC5B SSPOP OTOG	4.48e-04	19	150	3	SM00215
Domain	SRCR	SSC5D SSC4D DMBT1	6.07e-04	21	150	3	PF00530
Domain	IGc2	NPHS1 SEMA3F OBSCN OBSL1 ISLR FCRL5 BCAM IGSF3	6.34e-04	235	150	8	SM00408
Domain	Ig_sub2	NPHS1 SEMA3F OBSCN OBSL1 ISLR FCRL5 BCAM IGSF3	6.34e-04	235	150	8	IPR003598
Domain	RIH_assoc-dom	RYR3 ITPR2	9.41e-04	6	150	2	IPR013662
Domain	E1_dh	PDHA1 DHTKD1	9.41e-04	6	150	2	PF00676
Domain	Ins145_P3_rec	RYR3 ITPR2	9.41e-04	6	150	2	PF08709
Domain	DH_E1	PDHA1 DHTKD1	9.41e-04	6	150	2	IPR001017
Domain	RIH_assoc	RYR3 ITPR2	9.41e-04	6	150	2	PF08454
Domain	RIH_dom	RYR3 ITPR2	9.41e-04	6	150	2	IPR000699
Domain	Ins145_P3_rcpt	RYR3 ITPR2	9.41e-04	6	150	2	IPR014821
Domain	Ryanodine_recept-rel	RYR3 ITPR2	9.41e-04	6	150	2	IPR015925
Domain	-	RYR3 ITPR2	9.41e-04	6	150	2	1.25.10.30
Domain	RYDR_ITPR	RYR3 ITPR2	9.41e-04	6	150	2	PF01365
Domain	-	SSC5D SSC4D DMBT1	1.03e-03	25	150	3	3.10.250.10
Domain	Cys_knot_C	MUC5B SSPOP OTOG	1.03e-03	25	150	3	IPR006207
Domain	CTCK_2	MUC5B SSPOP OTOG	1.03e-03	25	150	3	PS01225
Domain	PH_dom-like	ARHGEF19 OBSCN APBA3 ECT2 LYST PLEKHH1 SPTBN5 PTPN4 MTMR4 SBF1	2.36e-03	426	150	10	IPR011993
Domain	MIR	RYR3 ITPR2	2.76e-03	10	150	2	PF02815
Domain	MIR_motif	RYR3 ITPR2	2.76e-03	10	150	2	IPR016093
Domain	MIR	RYR3 ITPR2	2.76e-03	10	150	2	PS50919
Domain	MIR	RYR3 ITPR2	2.76e-03	10	150	2	SM00472
Domain	TPR_7	NOXA1 TONSL	2.76e-03	10	150	2	PF13176
Domain	IGv	OBSCN SIRPG NECTIN2 IGSF3	3.12e-03	75	150	4	SM00406
Domain	NTP_transf_2	TUT4 PAPOLA	3.36e-03	11	150	2	PF01909
Domain	Polymerase_NTP_transf_dom	TUT4 PAPOLA	3.36e-03	11	150	2	IPR002934
Domain	LDLR_class-A_CS	SSPOP MAMDC4 CORIN	4.04e-03	40	150	3	IPR023415
Domain	C2-set_2	NPHS1 NECTIN2 BCAM	4.33e-03	41	150	3	PF08205
Domain	CD80_C2-set	NPHS1 NECTIN2 BCAM	4.33e-03	41	150	3	IPR013162
Domain	-	ARHGEF19 OBSCN APBA3 ECT2 PLEKHH1 SPTBN5 PTPN4 MTMR4 SBF1	4.39e-03	391	150	9	2.30.29.30
Domain	VWF_dom	MUC5B SSPOP OTOG	4.63e-03	42	150	3	IPR001007
Domain	THDP-binding	PDHA1 DHTKD1	4.72e-03	13	150	2	IPR029061
Domain	-	PDHA1 DHTKD1	4.72e-03	13	150	2	3.40.50.970
Domain	Ig_V-set	NPHS1 OBSCN SIRPG NECTIN2 BCAM IGSF3	5.46e-03	199	150	6	IPR013106
Domain	Myotubularin-like_Pase_dom	MTMR4 SBF1	5.47e-03	14	150	2	IPR010569
Domain	PPASE_MYOTUBULARIN	MTMR4 SBF1	5.47e-03	14	150	2	PS51339
Domain	Myotubularin_fam	MTMR4 SBF1	5.47e-03	14	150	2	IPR030564
Domain	Myotub-related	MTMR4 SBF1	5.47e-03	14	150	2	PF06602
Domain	DAGKc	CERK DGKZ	5.47e-03	14	150	2	SM00046
Domain	Ldl_recept_a	SSPOP MAMDC4 CORIN	5.63e-03	45	150	3	PF00057
Domain	PDZ	SYNPO2 MYO18A APBA3 PTPN4 PDZD2	5.64e-03	141	150	5	PF00595
Domain	-	SSPOP MAMDC4 CORIN	5.99e-03	46	150	3	4.10.400.10
Domain	Diacylglycerol_kinase_cat_dom	CERK DGKZ	6.28e-03	15	150	2	IPR001206
Domain	DAGK	CERK DGKZ	6.28e-03	15	150	2	PS50146
Domain	DAGK_cat	CERK DGKZ	6.28e-03	15	150	2	PF00781
Domain	IG_LIKE	NPHS1 SEMA3F OBSCN OBSL1 ISLR SIRPG NECTIN2 FCRL5 BCAM IGSF3	6.38e-03	491	150	10	PS50835
Domain	LDLRA_1	SSPOP MAMDC4 CORIN	6.74e-03	48	150	3	PS01209
Domain	PDZ	SYNPO2 MYO18A APBA3 PTPN4 PDZD2	6.90e-03	148	150	5	SM00228
Domain	IG	NPHS1 SEMA3F OBSCN OBSL1 SIRPG NECTIN2 FCRL5 BCAM IGSF3	7.03e-03	421	150	9	SM00409
Domain	Ig_sub	NPHS1 SEMA3F OBSCN OBSL1 SIRPG NECTIN2 FCRL5 BCAM IGSF3	7.03e-03	421	150	9	IPR003599
Domain	LDrepeatLR_classA_rpt	SSPOP MAMDC4 CORIN	7.14e-03	49	150	3	IPR002172
Domain	LDLa	SSPOP MAMDC4 CORIN	7.14e-03	49	150	3	SM00192
Domain	LDLRA_2	SSPOP MAMDC4 CORIN	7.14e-03	49	150	3	PS50068
Domain	PH	CERK ARHGEF19 OBSCN ECT2 PLEKHH1 SPTBN5 SBF1	7.27e-03	278	150	7	SM00233
Domain	-	NPHS1 SEMA3F MYCBP2 OBSCN OBSL1 ISLR SIRPG NECTIN2 FCRL5 BCAM TRIM36 IGSF3	7.29e-03	663	150	12	2.60.40.10
Domain	-	SYNPO2 MYO18A APBA3 PTPN4 PDZD2	7.29e-03	150	150	5	2.30.42.10
Domain	PDZ	SYNPO2 MYO18A APBA3 PTPN4 PDZD2	7.49e-03	151	150	5	PS50106
Domain	Ig-like_dom	NPHS1 SEMA3F OBSCN OBSL1 ISLR SIRPG NECTIN2 FCRL5 BCAM IGSF3	7.50e-03	503	150	10	IPR007110
Domain	PH_domain	CERK ARHGEF19 OBSCN ECT2 PLEKHH1 SPTBN5 SBF1	7.55e-03	280	150	7	IPR001849
Domain	PDZ	SYNPO2 MYO18A APBA3 PTPN4 PDZD2	7.70e-03	152	150	5	IPR001478
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SCFD2 CDK17 CDK18 DSC3 MYCBP2 PDHA1 DDX42 APAF1 MRPL53 MYO18A OBSL1 FTSJ1 NCDN ITPR2 IGF2R PPP6C SBF1 NECTIN2 PDCD11 MRPS5 DDHD2 FSCN1 DNA2 ATP2A2 ABHD12	7.37e-09	1487	152	25	33957083
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	DSC3 TRIP6 MYCBP2 USP9X PPM1J ITPR2 ACSL4 PTPN4 MTMR4 IGF2R ZFYVE9 PPP6C SBF1 SVIL NECTIN2 USP12 TRIM36 ATP2A2 NOTCH1 PPP1R12C	3.64e-08	1049	152	20	27880917
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	LRRC8E SEMA3F ARHGEF19 MYCBP2 RDH10 OBSCN TRMT1 EXTL3 LYST TUBG1 ITPR2 IGF2R SBF1 HELZ2 NAV2 PDCD11 WDR90 BCAM NOTCH1 IGSF3	8.45e-08	1105	152	20	35748872
Pubmed	Neuronal calcium sensor-1 promotes immature heart function and hypertrophy by enhancing Ca2+ signals.	ITPR2 CACNA1G ATP2A2	4.51e-06	8	152	3	21737792
Pubmed	Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.	RYR3 ITPR2 ATP2A2	4.51e-06	8	152	3	19033399
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	CR1L ITGB2 ITPR2 ADRB2 FCRL5 NOTCH1	5.68e-06	101	152	6	23382219
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDK17 CDK18 TRIP6 MYCBP2 ECT2 LYST DDX1 NEK4 MTMR4 SBF1 SVIL NECTIN2 NAV2 PPP1R12C OTOG	6.15e-06	861	152	15	36931259
Pubmed	TRIP6 functions in brain ciliogenesis.	TRIP6 TUBG2 TUBG1	6.74e-06	9	152	3	34620853
Pubmed	Proteomic and functional evidence for a P2X7 receptor signalling complex.	LAMA3 ITGB2 SVIL	1.32e-05	11	152	3	11707406
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	ZFAND2A ACP7 TUT4 NOXA1 APAF1 TRMT1 FTSJ1 TERT TEX22 PAPOLA TAMM41 NECTIN2 WDR90 DMBT1 HNRNPLL	1.43e-05	925	152	15	28986522
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	TRIP6 NOXA1 MYO18A RAD54L2 SSPOP RASSF5 ARL4C ATXN7 CACNA1G HNRNPLL ITPRIPL1 NOTCH1	1.62e-05	608	152	12	16713569
Pubmed	Tumorigenic potential of olfactory bulb-derived human adult neural stem cells associates with activation of TERT and NOTCH1.	TERT NOTCH1	1.90e-05	2	152	2	19209236
Pubmed	Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta.	DGKZ PRKCA	1.90e-05	2	152	2	9716136
Pubmed	FANCC suppresses short telomere-initiated telomere sister chromatid exchange.	TERT FANCC	1.90e-05	2	152	2	20022886
Pubmed	Cell micropatterning reveals the modulatory effect of cell shape on proliferation through intracellular calcium transients.	ITPR2 ATP2A2	1.90e-05	2	152	2	28962833
Pubmed	Fanconi anemia genes in lung adenocarcinoma- a pathway-wide study on cancer susceptibility.	FANCC BRCA2	1.90e-05	2	152	2	26842001
Pubmed	Interference with BRCA2, which localizes to the centrosome during S and early M phase, leads to abnormal nuclear division.	TUBG1 BRCA2	1.90e-05	2	152	2	17286961
Pubmed	Robust homology-directed repair within mouse mammary tissue is not specifically affected by Brca2 mutation.	BRCA2 PIM1	1.90e-05	2	152	2	27779185
Pubmed	No evidence of association of FLJ10986 and ITPR2 with ALS in a large German cohort.	ITPR2 FGGY	1.90e-05	2	152	2	19464757
Pubmed	MTOC reorientation occurs during FcgammaR-mediated phagocytosis in macrophages.	TUBG2 TUBG1	1.90e-05	2	152	2	17442887
Pubmed	Overexpression of γ-tubulin in non-small cell lung cancer.	TUBG2 TUBG1	1.90e-05	2	152	2	22806905
Pubmed	Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation.	TERT FANCC	1.90e-05	2	152	2	9582020
Pubmed	Protein kinase C alpha-mediated phosphorylation of PIM-1L promotes the survival and proliferation of acute myeloid leukemia cells.	PIM1 PRKCA	1.90e-05	2	152	2	30017192
Pubmed	β(2)-Integrin and Notch-1 differentially regulate CD34(+)CD31(+) cell plasticity in vascular niches.	ITGB2 NOTCH1	1.90e-05	2	152	2	22865639
Pubmed	Allocation of gamma-tubulin between oocyte cortex and meiotic spindle influences asymmetric cytokinesis in the mouse oocyte.	TUBG2 TUBG1	1.90e-05	2	152	2	17287496
Pubmed	Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis.	NPHS1 PRKCA	1.90e-05	2	152	2	20419132
Pubmed	Association between MUC5B and TERT polymorphisms and different interstitial lung disease phenotypes.	MUC5B TERT	1.90e-05	2	152	2	24434656
Pubmed	Germline genetic variations in PDZD2 and ITPR2 genes are associated with clear cell renal cell carcinoma in Chinese population.	ITPR2 PDZD2	1.90e-05	2	152	2	26918600
Pubmed	Are MUC5B and TERT mutations genetic risk factors for pulmonary fibrosis in individuals with severe COVID-19?	MUC5B TERT	1.90e-05	2	152	2	36912407
Pubmed	Autophagy is involved in mouse kidney development and podocyte differentiation regulated by Notch signalling.	NPHS1 NOTCH1	1.90e-05	2	152	2	28158917
Pubmed	Differential expression of human γ-tubulin isotypes during neuronal development and oxidative stress points to a γ-tubulin-2 prosurvival function.	TUBG2 TUBG1	1.90e-05	2	152	2	28119396
Pubmed	Nephrin loss in experimental diabetic nephropathy is prevented by deletion of protein kinase C alpha signaling in-vivo.	NPHS1 PRKCA	1.90e-05	2	152	2	16955103
Pubmed	Potential role of PCTAIRE-2, PCTAIRE-3 and P-Histone H4 in amyloid precursor protein-dependent Alzheimer pathology.	CDK17 CDK18	1.90e-05	2	152	2	26885753
Pubmed	Inositol hexaphosphate represses telomerase activity and translocates TERT from the nucleus in mouse and human prostate cancer cells via the deactivation of Akt and PKCalpha.	TERT PRKCA	1.90e-05	2	152	2	16979586
Pubmed	Functional and Physical Interaction of Diacylglycerol Kinase ζ with Protein Kinase Cα Is Required for Cerebellar Long-Term Depression.	DGKZ PRKCA	1.90e-05	2	152	2	26586831
Pubmed	BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair.	BRCA2 PIM1	1.90e-05	2	152	2	38244544
Pubmed	Targeting deubiquitinase activity with a novel small-molecule inhibitor as therapy for B-cell malignancies.	USP9X USP24	1.90e-05	2	152	2	25814533
Pubmed	Interaction of fascin and protein kinase Calpha: a novel intersection in cell adhesion and motility.	PRKCA FSCN1	1.90e-05	2	152	2	14532112
Pubmed	Gene knockout analysis of two gamma-tubulin isoforms in mice.	TUBG2 TUBG1	1.90e-05	2	152	2	15893303
Pubmed	The relationship between MUC5B promoter, TERT polymorphisms and telomere lengths with radiographic extent and survival in a Chinese IPF cohort.	MUC5B TERT	1.90e-05	2	152	2	31653936
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	CDK17 CDK18 MYCBP2 DDX1 ACSL4 AARS2 FSCN1	2.16e-05	190	152	7	15161933
Pubmed	A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects.	NPHS1 TUBG2 TUBG1	2.27e-05	13	152	3	26859289
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CERK KDM5C ARHGAP4 IBTK SBF1 NAV2 PDCD11 CACNA1G WDR90 DNA2 IGSF3	2.29e-05	529	152	11	14621295
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	RYR3 ITPR2 CACNA1G ATP2A2	2.31e-05	38	152	4	30786075
Pubmed	A protein interaction landscape of breast cancer.	USP9X MYO18A MUC5B FANCC ACSL4 IGF2R BRCA2 SVIL NAV2 PDCD11 MRPS5 FSCN1	2.43e-05	634	152	12	34591612
Pubmed	Aberrant cochlear hair cell attachments caused by Nectin-3 deficiency result in hair bundle abnormalities.	TUBG2 TUBG1 NECTIN2	2.88e-05	14	152	3	24381198
Pubmed	Epicardial spindle orientation controls cell entry into the myocardium.	TUBG2 TUBG1 PRKCA	2.88e-05	14	152	3	20643355
Pubmed	Differential genomic imprinting regulates paracrine and autocrine roles of IGF2 in mouse adult neurogenesis.	TUBG2 TUBG1 IGF2R	3.58e-05	15	152	3	26369386
Pubmed	RPGRIP1L is required for stabilizing epidermal keratinocyte adhesion through regulating desmoglein endocytosis.	DSC3 TUBG2 TUBG1	4.40e-05	16	152	3	30689641
Pubmed	Calcium handling precedes cardiac differentiation to initiate the first heartbeat.	ITPR2 CACNA1G ATP2A2	5.32e-05	17	152	3	27725084
Pubmed	Fascin Is Critical for the Maintenance of Breast Cancer Stem Cell Pool Predominantly via the Activation of the Notch Self-Renewal Pathway.	FSCN1 NOTCH1	5.68e-05	3	152	2	27502039
Pubmed	Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex.	OBSCN OBSL1	5.68e-05	3	152	2	20133654
Pubmed	PKC alpha mediates beta-arrestin2-dependent nephrin endocytosis in hyperglycemia.	NPHS1 PRKCA	5.68e-05	3	152	2	21321125
Pubmed	Cellular stress induces TRB3/USP9x-dependent Notch activation in cancer.	USP9X NOTCH1	5.68e-05	3	152	2	27593927
Pubmed	The calcium ATPase SERCA2 regulates desmoplakin dynamics and intercellular adhesive strength through modulation of PKCα signaling.	PRKCA ATP2A2	5.68e-05	3	152	2	21156808
Pubmed	Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.	OBSCN OBSL1	5.68e-05	3	152	2	27989621
Pubmed	The gamma-tubulin gene family in humans.	TUBG2 TUBG1	5.68e-05	3	152	2	10903841
Pubmed	DNA damage induce gamma-tubulin-RAD51 nuclear complexes in mammalian cells.	TUBG1 BRCA2	5.68e-05	3	152	2	15897881
Pubmed	LFA-1/ICAM-1 Ligation in Human T Cells Promotes Th1 Polarization through a GSK3β Signaling-Dependent Notch Pathway.	ITGB2 NOTCH1	5.68e-05	3	152	2	27206767
Pubmed	Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism.	OBSCN OBSL1	5.68e-05	3	152	2	31098411
Pubmed	Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents.	FANCC BRCA2	5.68e-05	3	152	2	24418621
Pubmed	Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.	TAMM41 USP12	5.68e-05	3	152	2	21314694
Pubmed	Human TUBG2 gene is expressed as two splice variant mRNA and involved in cell growth.	TUBG2 TUBG1	5.68e-05	3	152	2	27015882
Pubmed	Characterization of the human homologue of the yeast spc98p and its association with gamma-tubulin.	TUBG2 TUBG1	5.68e-05	3	152	2	9566969
Pubmed	Changes in protein expression due to deleterious mutations in the FA/BRCA pathway.	FANCC BRCA2	5.68e-05	3	152	2	17977515
Pubmed	The Aurora A-HP1γ pathway regulates gene expression and mitosis in cells from the sperm lineage.	TUBG2 TUBG1	5.68e-05	3	152	2	26021315
Pubmed	IL-1beta enhances beta2-adrenergic receptor expression in human airway epithelial cells by activating PKC.	ADRB2 PRKCA	5.68e-05	3	152	2	11238007
Pubmed	Supervillin modulation of focal adhesions involving TRIP6/ZRP-1.	TRIP6 SVIL	5.68e-05	3	152	2	16880273
Pubmed	Molecular basis of the head-to-tail assembly of giant muscle proteins obscurin-like 1 and titin.	OBSCN OBSL1	5.68e-05	3	152	2	20489725
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	OBSCN OBSL1 ISLR NECTIN2 BCAM IGSF3	8.24e-05	162	152	6	25826454
Pubmed	Proximity labeling reveals dynamic changes in the SQSTM1 protein network.	TUT4 TRIP6 SHB OBSL1 PPP6C TAMM41 MRPS5 FSCN1	9.15e-05	322	152	8	39098523
Pubmed	Harnessing host enhancers of SARS-CoV-2 entry as novel targets for antiviral therapy.	IGF2R NECTIN2 BCAM IGSF3	1.01e-04	55	152	4	38945485
Pubmed	Wnt ligand/Frizzled 2 receptor signaling regulates tube shape and branch-point formation in the lung through control of epithelial cell shape.	ARHGEF19 TUBG2 TUBG1	1.03e-04	21	152	3	25114215
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	DSC3 SHB FTSJ1 IGF2R ZFYVE9 SBF1 TAMM41 NECTIN2 USP12	1.05e-04	421	152	9	36976175
Pubmed	PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family.	CDK17 CDK18	1.13e-04	4	152	2	1437147
Pubmed	Cilia organize ependymal planar polarity.	TUBG2 TUBG1	1.13e-04	4	152	2	20164345
Pubmed	Telomerase is controlled by protein kinase Calpha in human breast cancer cells.	TERT PRKCA	1.13e-04	4	152	2	9837921
Pubmed	A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human.	PDHA1 KDM5C	1.13e-04	4	152	2	7951230
Pubmed	SERCA2b and 3 play a regulatory role in store-operated calcium entry in human platelets.	ITPR2 ATP2A2	1.13e-04	4	152	2	18068335
Pubmed	Coinheritance of BRCA1 and BRCA2 mutations with Fanconi anemia and Bloom syndrome mutations in Ashkenazi Jewish population: possible role in risk modification for cancer development.	FANCC BRCA2	1.13e-04	4	152	2	15726604
Pubmed	STIM1 calcium sensor is required for activation of the phagocyte oxidase during inflammation and host defense.	ITGB2 PRKCA	1.13e-04	4	152	2	24493668
Pubmed	Loss of Necdin impairs myosin activation and delays cell polarization.	TUBG2 TUBG1	1.13e-04	4	152	2	20665884
Pubmed	Piezo mechanosensory channels regulate centrosome integrity and mitotic entry.	TUBG2 TUBG1	1.13e-04	4	152	2	36574677
Pubmed	Association of genetic variants in SEMA3F, CLEC16A, LAMA3, and PCSK2 with myocardial infarction in Japanese individuals.	SEMA3F LAMA3	1.13e-04	4	152	2	20036365
Pubmed	IGF-II/mannose-6-phosphate receptor signaling induced cell hypertrophy and atrial natriuretic peptide/BNP expression via Galphaq interaction and protein kinase C-alpha/CaMKII activation in H9c2 cardiomyoblast cells.	IGF2R PRKCA	1.13e-04	4	152	2	18434368
Pubmed	Protein kinase C alpha phosphorylates and negatively regulates diacylglycerol kinase zeta.	DGKZ PRKCA	1.13e-04	4	152	2	12890670
Pubmed	Interaction between the integrin Mac-1 and signal regulatory protein α (SIRPα) mediates fusion in heterologous cells.	ITGB2 SIRPG	1.13e-04	4	152	2	30910815
Pubmed	Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1.	FANCC BRCA2	1.13e-04	4	152	2	16859999
Pubmed	Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells.	TUBG2 TUBG1	1.13e-04	4	152	2	16798874
Pubmed	The ubiquitin-specific protease 12 (USP12) is a negative regulator of notch signaling acting on notch receptor trafficking toward degradation.	USP12 NOTCH1	1.13e-04	4	152	2	22778262
Pubmed	Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain.	TUBG2 TUBG1 CORIN	1.19e-04	22	152	3	26542012
Pubmed	Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling.	USP9X USP24 USP12	1.19e-04	22	152	3	26811477
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	SCFD2 ZNF142 PDHA1 USP9X USP24 FER1L6 PLEKHH1 NEK4 ACSL4 ATXN7 IGSF3	1.22e-04	638	152	11	31182584
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	CDK18 CERK USP9X MYO18A DGKZ NCDN ITPR2 SBF1 USP12	1.23e-04	430	152	9	32581705
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	CDK17 CDK18 USP9X USP24 PRUNE1 ACSL4 IGF2R AARS2 PAPOLA UBIAD1 FSCN1 ATP2A2 SORD	1.35e-04	878	152	13	37223481
Pubmed	PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division.	TUBG2 TUBG1 NOTCH1	1.36e-04	23	152	3	31504280
Pubmed	Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.	CDK18 FAM185A PDHA1 MRPL53 TRMT1 ACSL4 ARL4C PDF AARS2 TAMM41 AGMAT MRPS5 SLC25A47 DNA2 DHTKD1	1.45e-04	1136	152	15	34800366
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYCBP2 PDHA1 USP9X DDX42 USP24 IGF2R SBF1 HELZ2 PDCD11 FSCN1 ATP2A2	1.49e-04	653	152	11	22586326
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	MYCBP2 USP9X KRT82 DDX42 OBSL1 NCDN DDX1 ITPR2 IGF2R AARS2 SVIL PDCD11 PRKCA ATP2A2	1.70e-04	1024	152	14	24711643
Pubmed	Neural tube defects by NUAK1 and NUAK2 double mutation.	TUBG2 TUBG1 PRKCA	1.75e-04	25	152	3	22689267
Interaction	RHOA interactions	ARHGEF19 SYNPO2 DSC3 TRIP6 PDHA1 USP9X MYO18A FTSJ1 ECT2 DDX1 ITPR2 ACSL4 IGF2R ZFYVE9 PPP6C SBF1 TAMM41 NECTIN2 PDCD11 MRPS5 PRKCA IRGC UBIAD1 ATP2A2 NOTCH1 IGSF3	9.02e-07	1199	151	26	int:RHOA
Interaction	ALPK2 interactions	CERK TRIP6 MYCBP2 OBSL1 NEK4	1.56e-06	27	151	5	int:ALPK2
Interaction	YWHAZ interactions	CDK17 CDK18 SYNPO2 DSC3 RPS6KA5 MYCBP2 MYO18A OBSL1 ECT2 TERT ITGB2 LYST TUBG1 NEK4 PTPN4 MTMR4 SBF1 SVIL NECTIN2 NAV2 PRKCA PRR14L ATP2A2 PPP1R12C OTOG	1.58e-05	1319	151	25	int:YWHAZ
Interaction	PTGES3 interactions	CERK RPS6KA5 DGKZ TERT NCDN PLEKHH1 NEK4 IBTK SBF1 BRCA2 PDCD11 PRR14L DNA2	2.61e-05	437	151	13	int:PTGES3
Cytoband	1p32.3	TUT4 USP24 ZFYVE9 MROH7	5.20e-05	61	152	4	1p32.3
Cytoband	Ensembl 112 genes in cytogenetic band chr1p32	TUT4 USP24 ZFYVE9 MROH7 FGGY	1.75e-04	155	152	5	chr1p32
GeneFamily	Immunoglobulin like domain containing	NPHS1 SEMA3F OBSL1 NECTIN2 FCRL5 BCAM IGSF3	1.59e-04	193	108	7	594
GeneFamily	X-linked mental retardation\|Angiotensin receptors	USP9X KDM5C FTSJ1 ACSL4	2.81e-04	53	108	4	103
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	NPHS1 NECTIN2 BCAM	1.74e-03	40	108	3	592
GeneFamily	UPF1 like RNA helicases	HELZ2 DNA2	1.88e-03	11	108	2	1169
GeneFamily	PDZ domain containing	SYNPO2 MYO18A APBA3 PTPN4 PDZD2	2.19e-03	152	108	5	1220
Coexpression	DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN	KDM5C OBSL1 FTSJ1 NCDN ARHGAP4 IGF2R SBF1 FSCN1 ATP2A2 IGSF3	5.14e-06	276	152	10	M3063
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	CDK17 TUT4 MYCBP2 USP9X DDX42 SHB USP24 NEK4 ACSL4 IBTK PTPN4 IGF2R ZFYVE9 UBE2G1 BRCA2 USP12 PRKCA	1.04e-05	856	152	17	M4500
Coexpression	GSE10325_CD4_TCELL_VS_BCELL_UP	CERK SIRPG ARL4C PTPN4 IGF2R PIM1 SVIL PRKCA	2.21e-05	199	152	8	M3076
Coexpression	GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_UP	CERK ZNF142 MYCBP2 MYO18A ZNF467 MTMR4 IGF2R ADRB2	2.29e-05	200	152	8	M3675
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DHX58 LAMA3 FER1L6 PLEKHH1 AGMAT CORIN DMBT1	1.68e-07	118	152	7	3f0a304ef9c9e5ba047fc09f4372590eed624328
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	OBSCN HMBS HDHD2 CR1L TONSL DCHS1 PRR14L	1.83e-06	168	152	7	8697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCell	droplet-Liver-LIVER-NPC-1m-Endothelial-Hepatocyte_(Pericentral)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F NEU3 FTSJ1 FANCC DCHS1 BCAM NOTCH1	2.40e-06	175	152	7	98dc3b6f69a29d587f503898f09912700950e3d9
ToppCell	wk_08-11-Mesenchymal-Mesothelial-Early_mesothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NPHS1 RDH10 SSC4D SVIL NECTIN2 PYGM BCAM	3.86e-06	188	152	7	6151051c027c7ff7d5d4bf5f1e11d7fe58eb22ed
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NPHS1 RDH10 LAMA3 SSC4D NAV2 PYGM BCAM	4.28e-06	191	152	7	4c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-CD4+_CTL\|Int-URO / Disease, condition lineage and cell class	ARHGEF19 SYNPO2 TUBG2 PTPN4 ZFYVE9 TAFA1 DNA2	5.42e-06	198	152	7	717735d755745439f97ba1b71785c73945dfa9c5
ToppCell	Int-URO-Lymphocyte-T_NK-CD4_CTL\|Int-URO / Disease, Lineage and Cell Type	ARHGEF19 SYNPO2 PTPN4 ZFYVE9 TAFA1 DNA2	1.44e-05	153	152	6	fdc7dfa8f4db90bfdc7180bf178cf6d2dd064d97
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RYR3 ARL4C SVIL PYGM DMBT1 IGSF3	1.55e-05	155	152	6	99e749f7075e2c64e9a0bf91009f95b6969197c8
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	APAF1 NEU3 ITGB2 LYST RASSF5 PIM1	1.67e-05	157	152	6	8c42af7aa1f1b6f4fe2f8d00a8b4a800f121e804
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	APAF1 NEU3 ITGB2 LYST RASSF5 PIM1	1.67e-05	157	152	6	ee1be3c756b72fceac6b4ccb416dd4bd031a2193
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	APAF1 NEU3 ITGB2 LYST RASSF5 PIM1	1.67e-05	157	152	6	008f938a338f43c3251dcac574f1b4f689926c71
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DHX58 PPM1J ITGB2 LYST SLC29A4 PDZD2	1.80e-05	159	152	6	709b57f992a29878cc899d760d144d36cb5cb280
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDK18 RPS6KA5 ITPR2 PTPN4 IGF2R PDZD2	2.37e-05	167	152	6	b0eb7a40491dd2432f5282f578ce569df86d21a7
ToppCell	Monocytes-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	ZNF467 TYMP ITGB2 LYST ARHGAP4 URAD	2.62e-05	170	152	6	4e93b66b3033e6e4d5f6d2f41974623a53108f5e
ToppCell	356C-Myeloid-Monocyte-CD16+_Monocyte\|Monocyte / Donor, Lineage, Cell class and subclass (all cells)	FAM185A ZNF584 ECT2 AARS2 TAMM41 DDHD2	2.80e-05	172	152	6	9dca1542145d88559527db7e0f6ad150df59ca2d
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CERK FAM185A DHX58 RDH10 DCHS1 PYGM	3.28e-05	177	152	6	8dfadd9852e0c256363471a7cfe6af120c8c51e0
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CERK FAM185A DHX58 RDH10 DCHS1 PYGM	3.28e-05	177	152	6	767b2af5f224d100b22bed32f86cec1cd17e8711
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CERK FAM185A DHX58 RDH10 DCHS1 PYGM	3.28e-05	177	152	6	5ef2527e9b41e62f1724cdabaad9d8979266bb7d
ToppCell	E18.5-Endothelial-Endothelial_lymphatic\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CERK FAM185A DHX58 RDH10 DCHS1 PYGM	3.28e-05	177	152	6	ae1d2fdd4f67f50c906b27ea084de058c6908aa2
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tnaive/CM_CD4\|GI_large-bowel / Manually curated celltypes from each tissue	OBSCN TRMT1 ARL4C SVIL PYGM SORD	3.28e-05	177	152	6	eb87ea93e36a8f97442ec8515f658ee61932dc0f
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGEF19 OBSL1 MTMR4 PDCD11 FGGY IGSF3	3.39e-05	178	152	6	cb9a446c145b1435cfe12a1d4568aed0924a6a20
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNPO2 RPS6KA5 ISLR TAFA1 CACNA1G PDZD2	3.84e-05	182	152	6	cc6f9d606a4f8717dc44928ceec2a257636043fd
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8E TUBG2 MATN4 TAFA1 RASGEF1C SLC25A47	3.84e-05	182	152	6	c00e503f442d44fbae73c5e2dc85be69e294e67a
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA3F ACP7 SHB RDH10 PPM1J NECTIN2	3.95e-05	183	152	6	2dde2fb48e7d31271c2f6b1dd74b2ab0b2cb520c
ToppCell	facs-Spleen-nan-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPM1J ITGB2 ARL4C IGF2R HNRNPLL NOTCH1	4.08e-05	184	152	6	c37c623c4a5ff1628486d8a6461fa355ad5c264c
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SYNPO2 EFHB SSC5D DCHS1 CORIN CACNA1G	4.46e-05	187	152	6	8bd635abdee5d5a12a3f7bf74eab4282e8e40741
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SYNPO2 EFHB SSC5D DCHS1 CORIN CACNA1G	4.46e-05	187	152	6	3cb8cd7f7a4306ff74d1f7f9964014008ec1c6a0
ToppCell	IPF-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	DSC3 LAMA3 ACSL4 SVIL BCAM NOTCH1	4.87e-05	190	152	6	4f15842b424eefadbfe451875e517cf70e29607f
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	SYNPO2 OBSCN SVIL CORIN ATP2A2 PDZD2	5.02e-05	191	152	6	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPHS1 DSC3 SSC4D NECTIN2 PYGM BCAM	5.17e-05	192	152	6	2f539653a20006bef814e6b4acd1023d6fdad5c6
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CERK SIRPG ARL4C PTPN4 ADRB2 PIM1	5.63e-05	195	152	6	c7b54b210cc2c8ddaefebfba74381adb2ca698b8
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CERK SIRPG ARL4C PTPN4 ADRB2 PIM1	5.63e-05	195	152	6	e173a713d273b135db4f71bdcaada3b0e55d74f1
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CERK SIRPG ARL4C PTPN4 ADRB2 PIM1	5.63e-05	195	152	6	59164d115a0928cc9b79c7661c7190ad695f9d80
ToppCell	wk_08-11-Mesenchymal-Mesothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NPHS1 RDH10 SVIL NECTIN2 PYGM BCAM	5.63e-05	195	152	6	9016a44b521214546a55a822ebdef5b5312206d2
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CERK SIRPG ARL4C PTPN4 ADRB2 PIM1	5.63e-05	195	152	6	a8fd42ff6c2bd80d0e3f20fe3bbf7d113b399df1
ToppCell	CV-Severe-1\|CV / Virus stimulation, Condition and Cluster	DHX58 TYMP ITGB2 LYST PIM1 HELZ2	6.13e-05	198	152	6	fc0e885e370ffb780eada62bb2b52065c2f8b26b
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4\|lymph-node_spleen / Manually curated celltypes from each tissue	SIRPG ARL4C ATXN7 PIM1 PRKCA HNRNPLL	6.13e-05	198	152	6	2cbafcb03df3c9aca68371df500d18ab8dcc416c
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SEMA3F DSC3 OBSCN LAMA3 BCAM IGSF3	6.30e-05	199	152	6	94a7867e800df352731796de8c24cba133c29622
ToppCell	BAL-Severe-cDC_10\|Severe / Compartment, Disease Groups and Clusters	SYNPO2 NEU3 LYST MTMR4 USP12 FSCN1	6.30e-05	199	152	6	54bdadd04abaf8caa948b0177c037bc089ca07e6
ToppCell	Sepsis-Bac-SEP-Lymphocyte-T/NK-CD4+_CTL\|Bac-SEP / Disease, condition lineage and cell class	ARL4C PTPN4 ADRB2 BCAM SLC29A4 ZNF239	6.48e-05	200	152	6	78cce90288ee7224067f7b87c99c54737bed466d
ToppCell	Control-Control-Lymphocyte-T/NK-MAIT\|Control / Disease, condition lineage and cell class	CERK SIRPG ARL4C PTPN4 ADRB2 PIM1	6.48e-05	200	152	6	888a8045e0457cd9d0c570360cca20a6efb44f13
ToppCell	droplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l14\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDK17 LYST SSC4D UBIAD1 PPP1R12C	9.02e-05	132	152	5	14a512f433315892bf0326419f23d0d5919d01ec
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	DSC3 APAF1 OBSCN LAMA3	9.65e-05	70	152	4	8d6bdf2e773e894a0db39fdff1fafc2474e03fcf
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DHX58 LAMA3 PLEKHH1 CORIN PYGM	1.19e-04	140	152	5	2c44e8cc5190226049be7ebc465d685393e701c4
ToppCell	NS-critical-d_0-4-Myeloid-pDC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANKRD62 TEX22 PDF FCRL5 DHTKD1	1.36e-04	144	152	5	0fde5cd82df9b90aefde19275cff6c2ec3c9d5cb
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Rbp4-Inhibitory_Neuron.Gad1Gad2_Sst.Rbp4_(Interneuron,_OLM2_(CA1_enriched?))\|Hippocampus / BrainAtlas - Mouse McCarroll V32	DHX58 FER1L6 AGMAT CORIN	1.40e-04	77	152	4	9a29879348b32b6c2302820f75fd55efba39aae8
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Rbp4-Inhibitory_Neuron.Gad1Gad2_Sst.Rbp4_(Interneuron,_OLM2_(CA1_enriched?))-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	DHX58 FER1L6 AGMAT CORIN	1.40e-04	77	152	4	c5262a0d2040b2c580601e5a8d1ec626a0c7b560
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Rbp4\|Hippocampus / BrainAtlas - Mouse McCarroll V32	DHX58 FER1L6 AGMAT CORIN	1.40e-04	77	152	4	3763b55e5ce44b844da661e9024c9f2c847ea26f
ToppCell	Children_(3_yrs)-Immune-mast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANKRD62 EXTL3 RYR3 ACSL4 PRKCA	1.45e-04	146	152	5	f7349d63bb47f1f22ced8ff514edc1c11bc782e7
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Akr1c18_Ntf3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DHX58 NOXA1 LAMA3 CORIN PYGM	1.59e-04	149	152	5	1e77f03d2b32f366018fec3462d1b75f6e7febb9
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RYR3 ARL4C SVIL PYGM IGSF3	1.59e-04	149	152	5	10ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_dendritic-myeloid_dendritic_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TYMP PPM1J CR1L SSC4D TRIM36	1.59e-04	149	152	5	71d72a6e7b128ee96161e08f6a0d77be925e73a1
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDK18 ISLR SVIL PRKCA CACNA1G	1.64e-04	150	152	5	909ccab92855f5f049dc29593aadab1ea973297b
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	NPHS1 CNNM2 ZNF142 SSC5D PRKCA	1.64e-04	150	152	5	744050a1b665c6989f37141348af3df7579a73c9
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Krt80_Sla\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SHB OBSCN ISLR RYR3 SPTBN5	1.70e-04	151	152	5	f50c5ae9dae507df750df25e151b58685fec70ce
ToppCell	PND01-Immune-Immune_Myeloid-DC-cDC2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCFD2 DHX58 RASSF5 ARHGAP4 DNA2	1.75e-04	152	152	5	cefc0ab592e99badf145fb95adf9906cb81be81c
ToppCell	PND01-Immune-Immune_Myeloid-DC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCFD2 DHX58 RASSF5 ARHGAP4 DNA2	1.75e-04	152	152	5	c8faa83dcaddb2ce2bb890f90dd8e676f7dcb1b3
ToppCell	PND01-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCFD2 DHX58 RASSF5 ARHGAP4 DNA2	1.75e-04	152	152	5	c3f00beb8b6fde99263d5ed6bbe3c2415d02f91d
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|Liver / Manually curated celltypes from each tissue	DPYS RPS6KA5 PYGM DMBT1 PDZD2	1.86e-04	154	152	5	c6308074468235c88ef4ea43ab155d9f86cbf261
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SYNPO2 NEU3 RYR3 DCHS1 DDHD2	1.86e-04	154	152	5	16fdafb5c64d2db321554f87129a962d113f1668
ToppCell	Children_(3_yrs)-Immune-mast_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RPS6KA5 EXTL3 RYR3 ACSL4 PRKCA	2.03e-04	157	152	5	ec185dbeabb67fd9ca85f71cab88463b60f9b1c1
ToppCell	droplet-Liver-Hepatocytes-21m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYS TERT AGMAT SLC25A47 SORD	2.16e-04	159	152	5	0f6ff73410fd6a6f97a53cb865952963a73848dd
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DPYS MUC5B CR1L PDF LSM11	2.28e-04	161	152	5	7c9d4410d7142a5f3a05418c994f69978c9ffa17
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYS OBSCN FTSJ1 TUBG1 ZNF394	2.35e-04	162	152	5	ca1014e32996f777bff021830ce9a7cf4acf58d5
ToppCell	facs-Spleen-nan-18m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK18 HMBS SNX21 CACNA1G DNA2	2.63e-04	166	152	5	8d535fab019356894b4dad3fbdbc4d2ad3e16082
ToppCell	facs-Spleen-nan-18m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK18 HMBS SNX21 CACNA1G DNA2	2.63e-04	166	152	5	f56b1c0d6cb5353a16a2598bda905287f16d2c39
ToppCell	facs-Spleen-nan-18m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK18 HMBS SNX21 CACNA1G DNA2	2.63e-04	166	152	5	a5074c96c6561273029aceb93402a7e038140f50
ToppCell	356C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	FAM185A ZNF584 ECT2 AARS2 DDHD2	2.70e-04	167	152	5	7e61c5d2cdcfa6a2e3484b3994aec6b64ad75f07
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NPHS1 ZNF142 HMBS SNX21 PRUNE1	2.78e-04	168	152	5	9e7b4b9b977e90e083f5164013e79df8bc2d492e
ToppCell	droplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITGB2 RASSF5 ADRB2 PIM1 ABHD12	2.78e-04	168	152	5	d823979335ac6b5d1f062ebb741c759d2f919dbf
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGB2 ARL4C PTPN4 ADRB2 PIM1	2.78e-04	168	152	5	696b31bedbc7d40817a733e8c6ec2633404be619
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TRIP6 FTCDNL1 MAMDC4 TUBG1 PDF	2.78e-04	168	152	5	3fb79aaa858057c82645a90bd139fc4f096323c7
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMA3 PPM1J PYGM BCAM IGSF3	2.78e-04	168	152	5	f3879a8e11eaf866f37c52e67021be43f0b8784a
ToppCell	droplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITGB2 RASSF5 ADRB2 PIM1 ABHD12	2.78e-04	168	152	5	f377ff4c066a9857ad14d245e56325ad220e22e1
ToppCell	343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	LAMA3 ECT2 BRCA2 WDR90 DNA2	2.86e-04	169	152	5	a949f547b53126a208819bade74a1ac9b2a36ea7
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	TRIP6 FTCDNL1 MAMDC4 TUBG1 PDF	2.86e-04	169	152	5	0589f39d8e9468e42d25d30ff70bb7cb8b921628
ToppCell	facs-Marrow-KLS-24m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F SNX21 FSCN1 DNA2 IGSF3	2.86e-04	169	152	5	d6ad3b637de2935c656aad47ad82d6e8a8bd1227
ToppCell	facs-Marrow-KLS-24m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3F SNX21 FSCN1 DNA2 IGSF3	2.86e-04	169	152	5	60ef186518d0dc63dbded2a77c65cfe3129df754
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAS1R3 OBSL1 ITPR2 NAV2 BCAM	2.86e-04	169	152	5	05e12524d68d409fed386ffad233305683b4575b
ToppCell	343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	LAMA3 ECT2 BRCA2 WDR90 DNA2	2.86e-04	169	152	5	195d5cd60d646ac6d40a3321b2f739917e7aef14
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	NATD1 LAMA3 BCAM IGSF3 PDZD2	2.94e-04	170	152	5	4cd3b7e43a061948084c01713ae141b5c2c07d89
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNPO2 DSC3 LAMA3 BCAM IGSF3	2.94e-04	170	152	5	0cc20322cb3e3e7bbd4daad8785c99f80e355c16
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNPO2 DSC3 LAMA3 BCAM IGSF3	2.94e-04	170	152	5	2d880223d01bde4bf777bd6f50b7d2768489075f
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)\|356C / Donor, Lineage, Cell class and subclass (all cells)	NATD1 LAMA3 BCAM IGSF3 PDZD2	2.94e-04	170	152	5	36c9f7f98612a72dc511c8da4358d67444f6bcf4
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_D\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SCFD2 NATD1 ZNF549 SPTBN5 IGF2R	3.02e-04	171	152	5	943fbca8a6ac04052a2a85aca7b21a3461cd96f7
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 NCDN ARL4C RASGEF1C BCAM	3.02e-04	171	152	5	f047a0cc2ce0a062ec502aa9cb91b1202f437f29
ToppCell	Nasal_Brush-Epithelial-Basal_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	SYNPO2 DSC3 ZNF668 BCAM FSCN1	3.10e-04	172	152	5	58eaadf12366701103a0d1f133462c9495fedc30
ToppCell	facs\|World / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TYMP ACSL4 PRR14L DDHD2 ITPRIPL1	3.10e-04	172	152	5	a2d0a64ebf09d219a07d6bbad1056bad6d46b9be
ToppCell	Nasal_Brush-Epithelial-Basal_1\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	SYNPO2 DSC3 ZNF668 BCAM FSCN1	3.10e-04	172	152	5	4483073469001770015526303772fd54906c5d68
ToppCell	367C-Lymphocytic-ILC-ILC-2\|367C / Donor, Lineage, Cell class and subclass (all cells)	ARHGEF19 DHX58 PTPN4 DHTKD1 ITPRIPL1	3.18e-04	173	152	5	0451450605521fecb27a958628870d268adfb023
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	TUBG2 MRPL53 MYO18A EFHB SVIL	3.18e-04	173	152	5	7e2149205e119cec4f5099c83c85d1e13470137a
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Lymphocytic-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK18 RAD54L2 NEK4 RASGEF1C ZNF239	3.27e-04	174	152	5	6987fe7959afce347282f632abc16d800ccab7c4
ToppCell	normal_Lung-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	HMBS TYMP DNA2 HNRNPLL SORD	3.27e-04	174	152	5	e324320b52c904496e26fcecfa179b3431729ec0
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA3F OBSCN TERT PLEKHH1 ATP2A2	3.27e-04	174	152	5	207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell	droplet-Lung-LUNG-1m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGB2 RASSF5 ADRB2 PIM1 ABHD12	3.35e-04	175	152	5	c8cfe0ac0c1ac447c626a623cc49692a0b177a1c
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGB2 RASSF5 ADRB2 PIM1 ABHD12	3.35e-04	175	152	5	61fbd8f685d3daad46449e4c0386a38886496566
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPHS1 DSC3 RDH10 SSC4D BCAM	3.35e-04	175	152	5	f5451c29c487b998778e50349b3d774d5e20fd28
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SYNPO2 SSPOP TAFA1 TRIM36 PDZD2	3.35e-04	175	152	5	2a53d4f140d5ab096efe8118d8aa351db7838b49
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SYNPO2 SSPOP TAFA1 TRIM36 PDZD2	3.35e-04	175	152	5	fb91a45763e4c48d993094a13088ffc19f1e2574
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-Treg\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGB2 SIRPG TEX22 RASSF5 ARL4C	3.44e-04	176	152	5	88247142c6482f3b4fa845d64e6189c690a5ee52
Disease	Tremor	ZNF142 ADRB2 ABHD12	1.94e-05	11	147	3	C0040822
Disease	complex cortical dysplasia with other brain malformations 4 (implicated_via_orthology)	TUBG2 TUBG1	2.47e-05	2	147	2	DOID:0090138 (implicated_via_orthology)
Disease	bronchiolitis (is_implicated_in)	MUC5B ADRB2	7.37e-05	3	147	2	DOID:2942 (is_implicated_in)
Disease	response to thiazide, low density lipoprotein cholesterol measurement	NECTIN2 BCAM	7.37e-05	3	147	2	EFO_0004611, EFO_0007981
Disease	Malignant neoplasm of urinary bladder	TYMP TERT FANCC BRCA2 NECTIN2 NOTCH1	7.78e-05	141	147	6	C0005684
Disease	schizophrenia, anorexia nervosa	CNNM2 FTCDNL1 DGKZ ATP2A2	9.70e-05	48	147	4	MONDO_0005090, MONDO_0005351
Disease	Interstitial lung disease 2	MUC5B TERT	1.47e-04	4	147	2	cv:C5561926
Disease	INTERSTITIAL LUNG DISEASE 2	MUC5B TERT	1.47e-04	4	147	2	178500
Disease	Skin Ulcer	LAMA3 ITGB2	1.47e-04	4	147	2	C0037299
Disease	teratoma (is_marker_for)	TYMP TERT	2.44e-04	5	147	2	DOID:3307 (is_marker_for)
Disease	ribitol measurement	FGGY SORD	2.44e-04	5	147	2	EFO_0800143
Disease	cholangiocarcinoma (is_marker_for)	MUC5B ADRB2 FSCN1 NOTCH1	2.98e-04	64	147	4	DOID:4947 (is_marker_for)
Disease	Hyporeflexia	ATXN7 ABHD12	3.65e-04	6	147	2	C0151888
Disease	Diffuse interstitial pulmonary fibrosis	MUC5B TERT	3.65e-04	6	147	2	cv:C0085786
Disease	severe acute respiratory syndrome, COVID-19	USP9X LYST RASSF5 PTPN4 TAFA1 USP12 PRKCA FGGY PDZD2	4.23e-04	447	147	9	EFO_0000694, MONDO_0100096
Disease	Mental Retardation, X-Linked 1	USP9X FTSJ1 ACSL4	5.40e-04	32	147	3	C2931498
Disease	free cholesterol measurement, low density lipoprotein cholesterol measurement	USP24 IGF2R NECTIN2 IRGC BCAM	6.32e-04	137	147	5	EFO_0004611, EFO_0008591
Disease	argininate measurement	IGF2R AGMAT	6.77e-04	8	147	2	EFO_0800055
Disease	basal cell adhesion molecule measurement	NECTIN2 BCAM	6.77e-04	8	147	2	EFO_0008032
Disease	common bile duct neoplasm (is_marker_for)	TYMP FSCN1	6.77e-04	8	147	2	DOID:4608 (is_marker_for)
Disease	Bladder Neoplasm	TYMP TERT FANCC NECTIN2 NOTCH1	6.97e-04	140	147	5	C0005695
Disease	cholesteryl esters to total lipids in medium LDL percentage	IGF2R NECTIN2 BCAM	8.31e-04	37	147	3	EFO_0022252
Disease	idiopathic pulmonary fibrosis (is_implicated_in)	MUC5B TERT	8.67e-04	9	147	2	DOID:0050156 (is_implicated_in)
Disease	non-syndromic X-linked intellectual disability (implicated_via_orthology)	FTSJ1 ACSL4	8.67e-04	9	147	2	DOID:0050776 (implicated_via_orthology)
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	USP24 IGF2R NECTIN2 HELZ2 IRGC BCAM	9.52e-04	225	147	6	EFO_0008317, EFO_0020947
Disease	ductal carcinoma in situ (is_marker_for)	TYMP TERT PRKCA	9.71e-04	39	147	3	DOID:0060074 (is_marker_for)
Disease	pneumonia (implicated_via_orthology)	ITGB2 ADRB2	1.08e-03	10	147	2	DOID:552 (implicated_via_orthology)
Disease	Fanconi anemia (is_implicated_in)	FANCC BRCA2	1.08e-03	10	147	2	DOID:13636 (is_implicated_in)
Disease	sleep duration, low density lipoprotein cholesterol measurement	USP24 IGF2R NECTIN2 BCAM	1.13e-03	91	147	4	EFO_0004611, EFO_0005271
Disease	ovarian carcinoma	SYNPO2 LAMA3 TERT UBE2G1 AARS2 TONSL HNRNPLL	1.17e-03	321	147	7	EFO_0001075
Disease	pulmonary fibrosis	MUC5B TERT	1.32e-03	11	147	2	EFO_0009448
Disease	smoking behaviour measurement, waist-hip ratio	NECTIN2 BCAM	1.32e-03	11	147	2	EFO_0004343, EFO_0005671
Disease	Mental Retardation, X-Linked Nonsyndromic	FTSJ1 ACSL4	1.85e-03	13	147	2	C3501611
Disease	phospholipids in medium LDL measurement	IGF2R NECTIN2 BCAM	1.89e-03	49	147	3	EFO_0022183
Disease	cholesterol in medium LDL measurement	IGF2R NECTIN2 BCAM	1.89e-03	49	147	3	EFO_0022224
Disease	cholesterol in small LDL measurement	IGF2R NECTIN2 BCAM	1.89e-03	49	147	3	EFO_0022227
Disease	free cholesterol to total lipids in small HDL percentage	ZFAND2A NECTIN2 BCAM	2.12e-03	51	147	3	EFO_0022285
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	USP24 HMBS IGF2R NECTIN2 HELZ2 BCAM	2.14e-03	264	147	6	EFO_0008317, EFO_0020944
Disease	nephroblastoma (is_implicated_in)	IGF2R BRCA2	2.16e-03	14	147	2	DOID:2154 (is_implicated_in)
Disease	Hamman-Rich syndrome	MUC5B TERT	2.16e-03	14	147	2	C0085786
Disease	Fanconi anemia	FANCC BRCA2	2.16e-03	14	147	2	cv:C0015625
Disease	total lipids in medium LDL	IGF2R NECTIN2 BCAM	2.24e-03	52	147	3	EFO_0022180
Disease	total lipids in LDL measurement	IGF2R NECTIN2 BCAM	2.24e-03	52	147	3	EFO_0022308
Disease	cancer (implicated_via_orthology)	HMBS TERT ITGB2 BRCA2 DNA2 NOTCH1	2.31e-03	268	147	6	DOID:162 (implicated_via_orthology)
Disease	Glioblastoma Multiforme	TERT PIM1 PRKCA NOTCH1	2.34e-03	111	147	4	C1621958
Disease	Neoplasm of uncertain or unknown behavior of bladder	FANCC NOTCH1	2.48e-03	15	147	2	C0496930
Disease	Benign neoplasm of bladder	FANCC NOTCH1	2.48e-03	15	147	2	C0154017
Disease	Carcinoma in situ of bladder	FANCC NOTCH1	2.48e-03	15	147	2	C0154091
Disease	Alzheimer disease, peptic ulcer disease, Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement, gastroesophageal reflux disease	CR1L NECTIN2	2.48e-03	15	147	2	EFO_0003948, EFO_0009923, MONDO_0004247, MONDO_0004975
Disease	Malignant neoplasm of breast	DSC3 OBSCN ECT2 TERT MAMDC4 ZNF668 TRMT2A BRCA2 PIM1 NECTIN2 MROH7 FCRL5 NOTCH1	2.85e-03	1074	147	13	C0006142
Disease	total lipids in large LDL	IGF2R NECTIN2 BCAM	2.91e-03	57	147	3	EFO_0022163
Disease	cholesterol in large LDL measurement	IGF2R NECTIN2 BCAM	2.91e-03	57	147	3	EFO_0021901
Disease	urate measurement, spine bone mineral density	DPYS NAV2 SORD	3.06e-03	58	147	3	EFO_0004531, EFO_0007701
Disease	low density lipoprotein cholesterol measurement, phospholipid measurement	BRCA2 NECTIN2 IRGC BCAM	3.11e-03	120	147	4	EFO_0004611, EFO_0004639
Disease	phospholipids in small LDL measurement	IGF2R NECTIN2 BCAM	3.21e-03	59	147	3	EFO_0022297
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	USP24 IGF2R NECTIN2 HELZ2 IRGC BCAM	3.46e-03	291	147	6	EFO_0008317, EFO_0020946
Disease	pancreatic ductal carcinoma (is_marker_for)	MUC5B TYMP FSCN1	3.53e-03	61	147	3	DOID:3587 (is_marker_for)
Disease	free cholesterol in VLDL measurement	IGF2R NECTIN2 BCAM	3.53e-03	61	147	3	EFO_0022276
Disease	Bone marrow hypocellularity	FANCC BRCA2	3.58e-03	18	147	2	C1855710
Disease	Carcinoma of bladder	FANCC NOTCH1	3.58e-03	18	147	2	C0699885
Disease	mean arterial pressure	ZFAND2A CNNM2 DGKZ TERT PRKCA SLC25A47 TRIM36 ATP2A2	3.64e-03	499	147	8	EFO_0006340
Disease	cholesteryl ester measurement, low density lipoprotein cholesterol measurement	IGF2R BRCA2 NECTIN2 BCAM	3.70e-03	126	147	4	EFO_0004611, EFO_0010351
Disease	Congenital hernia of foramen of Morgagni	IGF2R PIM1	3.99e-03	19	147	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	IGF2R PIM1	3.99e-03	19	147	2	C0265700
Disease	Usual Interstitial Pneumonia	MUC5B TERT	3.99e-03	19	147	2	C4721509
Disease	Hamman-Rich Disease	MUC5B TERT	3.99e-03	19	147	2	C4721508
Disease	age at onset, smoking initiation	MYCBP2 ITPR2	3.99e-03	19	147	2	EFO_0004847, EFO_0005670
Disease	etiocholanolone glucuronide measurement	ZNF394 SORD	3.99e-03	19	147	2	EFO_0800362
Disease	creatinine measurement	NPHS1 CDK18 RNF186 OBSCN PPM1J DDX1 IGF2R ATXN7 SVIL NECTIN2 AGMAT SORD	4.23e-03	995	147	12	EFO_0004518
Disease	myelodysplastic syndrome (is_marker_for)	DDX42 TERT	4.42e-03	20	147	2	DOID:0050908 (is_marker_for)
Disease	Familial Idiopathic Pulmonary Fibrosis	MUC5B TERT	4.42e-03	20	147	2	C4721952
Disease	Congenital diaphragmatic hernia	IGF2R PIM1	4.86e-03	21	147	2	C0235833
Disease	Idiopathic Pulmonary Fibrosis	MUC5B TERT	4.86e-03	21	147	2	C1800706

Protein segments in the cluster

Peptide	Gene	Start	Entry
EGILRCHPDLAGSEL	URAD	61	A6NGE7
VVGLDDLILSDHCRP	MAMDC4	411	Q6UXC1
IGEFHPDGCLQIIDR	ACSL4	556	O60488
EAVRDHSLLEGCFPG	APAF1	166	O14727
LLCEDLPGTEDFVGH	ADRB2	376	P07550
HVQPACAIIGEGLTE	ARL4C	156	P56559
RLEHEEGAPCTAIRE	CDK18	176	Q07002
PHAREQLGFCVEDGI	APBA3	491	O96018
LLLACAHGRPGVVAD	ANKRD62	76	A6NC57
GPDVVICDEGHRIKN	RAD54L2	456	Q9Y4B4
EGALIEPLSVGIHAC	SORD	151	Q00796
PGDRVICLQVHGDAS	DHTKD1	321	Q96HY7
TDEEGICHRTLLGPA	MUC5B	256	Q9HC84
LAPGEVVHDEGAVCS	MUC5B	761	Q9HC84
ILHIGDPDEEIGCEA	MROH7	616	Q68CQ1
CVHLLAGDPEAALRA	NOXA1	46	Q86UR1
PAERGEGHCFAELVL	RASSF5	116	Q8WWW0
VETISLGEHPCDRGE	ECT2	676	Q9H8V3
LGEHPCDRGEQVTLF	ECT2	681	Q9H8V3
PVVHVRGLCESVVEA	HNRNPLL	76	Q8WVV9
RAGKEEPVVVHCSAG	PTPN4	841	P29074
GLVDDRCVVHPEAGD	ITPR2	31	Q14571
EPVALEHERCAAAGS	ABHD12	6	Q8N2K0
RGPVHIITGSAGCEE	ACP7	361	Q6ZNF0
REEVPGCPEAHAVFL	ARHGEF19	146	Q8IW93
EGREHGIAVLECKVP	OBSL1	351	O75147
LHFGAPGRVELRCEV	OBSL1	1091	O75147
RPLHVVLGNEACDLD	PRUNE1	16	Q86TP1
DEGHVRAGQSLELPC	NPHS1	251	O60500
GAVDVVLEARDHGAP	DCHS1	2446	Q96JQ0
CAEHVPERLAAGTLV	NOTCH1	1561	P46531
HEGSPLGELHRCIRE	LSM11	151	P83369
HLLENLRGSICPEEG	MATN4	556	O95460
EGVLPEICDAHGRCL	LAMA3	496	Q16787
DGCPDHVLRALGVAL	NCDN	96	Q9UBB6
HGDEQTCLVPRLVEG	IBTK	211	Q9P2D0
LEALRGTGCEPEEAV	HDHD2	186	Q9H0R4
GHELCRPEAVEAEAT	DPYS	216	Q14117
PDGDRVLVAVCGVEG	FAM185A	96	Q8N0U4
CTDVAARGIDIHGVP	DDX1	571	Q92499
GAEIVVCTPGRLIDH	DDX42	376	Q86XP3
ELRPGFVLALHCDVD	ISLR	246	O14498
GDLLELHCEALRGSP	FCRL5	766	Q96RD9
EGQACRRVVHFAEPG	MYO18A	246	Q92614
EPGIGRSVAVHDALC	PDZD2	2736	O15018
AGECIIEKQGRIHPD	NEK4	506	P51957
RGVENISVDIHCGEP	DDHD2	196	O94830
LVFVVHGIGPACDLR	DDHD2	216	O94830
GEEHRLCEGIGPVNI	KRT82	426	Q9NSB4
RLGCGPRDADEIKEH	RPS6KA5	301	O75582
ELELVACGLERIPHA	LRRC8E	586	Q6NSJ5
EHEEGAPCTAIREVS	CDK17	226	Q00537
HVCQVGDPVLRGVAA	PDF	66	Q9HBH1
GALEQGCPIRVEHDR	NATD1	11	Q8N6N6
LSEREFDPDIHCGVI	ATXN7	336	O15265
DHCAERLREAGVADP	IRGC	196	Q6NXR0
VDREGRPVLVHCSDG	MTMR4	396	Q9NYA4
ADLDGGTVTIPECVH	SBF1	306	O95248
RGLVVHDVSPEDAGL	OBSCN	2701	Q5VST9
GADIDALCVAPRHVD	PAPOLA	111	P51003
GAILTPNDGRCHLED	ITGB2	276	P05107
RQEAHPQLEDCLGIG	ITPRIPL1	206	Q6GPH6
APEGVIDRCTHIRVG	ATP2A2	516	P16615
LHTVGEPVEFRCILE	IGSF3	291	O75054
HVRDLDEGPECTPAA	DSC3	461	Q14574
GPDCRFLIVAHDDGR	FSCN1	86	Q16658
IILHGAELVGSPDAC	BRCA2	2751	P51587
GVELFGDLECDETHP	CACNA1G	1761	O43497
ADVRGHGLICEGQPV	FGGY	271	Q96C11
CDGEVLHSPAIEVRV	CERK	501	Q8TCT0
GPRVGNELCEVKHVL	EXTL3	66	O43909
CELPVGAGSHDALIV	CR1L	541	Q2VPA4
VDPLVEALLICHGRE	FANCC	196	Q00597
AEEGLDIPHCNVVVR	DHX58	441	Q96C10
FPECIIDGDDSHGLL	CORIN	196	Q9Y5Q5
NPGERLIEEGCIHII	LYST	1526	Q99698
DCRAPGELEHGLITF	MASP1	366	P48740
ACLRPEEYGVGDLIH	EFHB	516	Q8N7U6
GLAEDLVLHVPGCSV	FTCDNL1	71	E5RQL4
VVVPGDSDLELCRAH	DGKZ	676	Q13574
GVLHDPETLLRCIAE	HMBS	236	P08397
DLGPRCEVAVHITDV	HELZ2	1361	Q9BYK8
GDEVTLICSARGHPD	BCAM	466	P50895
VEPGDIIHLEGDCTS	DNA2	91	P51530
SGPIVLDDVRCSGHE	DMBT1	661	Q9UGM3
SGPIVLDDVRCSGHE	DMBT1	1181	Q9UGM3
GPIVLDDVRCSGHES	DMBT1	1311	Q9UGM3
ETLDHGSEPGRCGLV	PRR14L	81	Q5THK1
QGLLRHGDACFLPEE	OTOG	931	Q6ZRI0
VCGDIPFEHDEEIIR	PIM1	236	P11309
VPGGLICSLRDHEAV	RNF186	91	Q9NXI6
EDIPEVGCRLVPEHI	FER1L6	1536	Q2WGJ9
RVEGDNCEVKDPRHG	IGF2R	1221	P11717
KGLHVVEIREECGPL	MRPS5	366	P82675
LHRPEGGTCEVIAAH	TAFA1	36	Q7Z5A9
HVRAVAEACQPGVEG	USP9X	1166	Q93008
PRTAAVGEICEEGLH	TRMT1	141	Q9NXH9
PGCEHDVDLGERGIN	TRIM36	116	Q9NQ86
GLPLEHVAGDRCIHE	TRMT2A	381	Q8IZ69
VIADVRHDGSEPCVD	MRPL53	51	Q96EL3
EPCVDVLFGDGHRLI	MRPL53	61	Q96EL3
HGSPEFCGILGERVD	SHB	386	Q15464
HAGQRPCDLADEEVL	PPP1R12C	291	Q9BZL4
RLVCSVPGEDGIETH	SEMA3F	321	Q13275
GLIDADVEPGHLRAE	SSPOP	376	A2VEC9
DVEPGHLRAEAQDVC	SSPOP	381	A2VEC9
EEGCVLLPEGTGRFH	SSPOP	2266	A2VEC9
EGDGRDSPVLHVCES	SVIL	411	O95425
LGCGPEGERDVREHA	PRKCA	581	P17252
EDSRPHLFLIGCIGV	NAV2	2031	Q8IVL1
EHCPDDVLVLGTDGL	PPM1J	416	Q5JR12
GPLHCLATVAREEGL	SLC25A47	161	Q6Q0C1
HGAPFRRCVDEGLLD	AGMAT	201	Q9BSE5
VCEHPLSDIVIAGEA	MYCBP2	3631	O75592
LEAVGGPDCHLREFE	SCFD2	46	Q8WU76
AVERLRLADGPHGCA	SSC5D	16	A1L4H1
CEVAHVTLQGDPLRG	SIRPG	226	Q9P1W8
AGVVSGHHLLECPDE	RDH10	146	Q8IZV5
LHEAVAPECLRLGDQ	AARS2	601	Q5JTZ9
GEDPLVEGCTAHDLD	ARHGAP4	561	P98171
EVGRLCQRSPEAAHG	SPTBN5	2426	Q9NRC6
GEIVPQAICSRHGLA	CNNM2	356	Q9H8M5
CEVAEVTGRAGHPVL	NEU3	226	Q9UQ49
IPDVVVGDHIDRDCD	ZFAND2A	71	Q8N6M9
GCIHASHILDDVPEG	PDCD11	1061	Q14690
ERPGAAGTQLHCRDV	TEX22	81	C9J3V5
AARGICIAHEGLVPL	TAS1R3	231	Q7RTX0
VVCHRGLDGIPFTVD	TRIP6	366	Q15654
GVLRSCPVDLGEHHA	WDR90	536	Q96KV7
EHCPESGEEAVAVVR	ZNF394	126	Q53GI3
VGCLHGIEAEEAPSE	ZNF549	66	Q6P9A3
VEHVECQDAGVREAP	ZNF668	481	Q96K58
AGDAGLPRVEVILDC	SYNPO2	276	Q9UMS6
CVGLEAGINPTDHLI	PDHA1	101	P08559
CNPGLAEVIAERIGE	PYGM	496	P11217
CAEHGISPEGIVEEF	TUBG1	26	P23258
DEQILCVHGGLSPDI	PPP6C	156	O00743
ILLDNVHCEGGEPRL	SSC4D	251	Q8WTU2
EAVQCSGAHIRDPVG	RYR3	1701	Q15413
DDPLGCAVAHRKIGE	TONSL	61	Q96HA7
IGHLKDVVGRIAPCD	RASGEF1C	131	Q8N431
LAGLAVCHQELEDPG	SNX21	286	Q969T3
DLVAVVVHCGSGPNR	USP12	301	O75317
HGVLDPRLLVGCAVA	UBIAD1	76	Q9Y5Z9
HDPDCGDVVRLGLSA	TAMM41	281	Q96BW9
LGCLPVRDAHIEEVD	PLEKHH1	726	Q9ULM0
DLVVCDGAPDVTGLH	FTSJ1	111	Q9UET6
SEGEPVALHAGICVR	USP24	1381	Q9UPU5
FPGLESEIRHCILGE	SLC29A4	371	Q7RTT9
CAEHGISPEGIVEEF	TUBG2	26	Q9NRH3
THQIRGCPLEESGEL	ZNF142	1121	P52746
LECLGVVEGDPHVLC	nan	171	Q8N1Y9
CIVNHRGEVDGEPEL	ZNF239	11	Q16600
ICGDAGHVRRECPEV	TUT4	1361	Q5TAX3
NGDVCISILHEPGED	UBE2G1	86	P62253
GLDGLCRVEDERAHP	ZNF584	96	Q8IVC4
PLGRCVGHALEVEEA	TYMP	276	P19971
VGCVPAAEHRLREEI	TERT	526	O14746
DLDSALVPVIHGGAC	ZFYVE9	1391	O95405
REERALGVCSGHEAP	ZNF467	41	Q7Z7K2
PCLDDLEGLVAVGRD	KDM5C	1046	P41229
EVRGQLGGTVELPCH	NECTIN2	41	Q92692