Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transporter activity	KCNA2 SLC31A2 ABCC8 TPTE2 SLC7A5 SLC36A3 ABCC12 PANX1 SLC13A3 APOB STRA6 ATP10A ANKH SLC7A14 SLC38A6 SLC38A3	1.69e-07	1289	54	16	GO:0005215
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	SLC7A5 SLC36A3 SLC13A3 SLC7A14 SLC38A6 SLC38A3	3.85e-07	105	54	6	GO:0015171
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC7A5 SLC36A3 PANX1 SLC13A3 ANKH SLC7A14 SLC38A6 SLC38A3	1.13e-06	293	54	8	GO:0008514
GeneOntologyMolecularFunction	L-amino acid transmembrane transporter activity	SLC7A5 SLC36A3 SLC13A3 SLC38A6 SLC38A3	1.36e-06	71	54	5	GO:0015179
GeneOntologyMolecularFunction	transmembrane transporter activity	KCNA2 SLC31A2 ABCC8 TPTE2 SLC7A5 SLC36A3 ABCC12 PANX1 SLC13A3 STRA6 ANKH SLC7A14 SLC38A6 SLC38A3	2.05e-06	1180	54	14	GO:0022857
GeneOntologyMolecularFunction	neutral L-amino acid transmembrane transporter activity	SLC7A5 SLC36A3 SLC38A6 SLC38A3	4.49e-06	41	54	4	GO:0015175
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLC7A5 SLC36A3 SLC13A3 SLC7A14 SLC38A6 SLC38A3	1.97e-05	207	54	6	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLC7A5 SLC36A3 SLC13A3 SLC7A14 SLC38A6 SLC38A3	2.02e-05	208	54	6	GO:0005342
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	SLC7A5 SLC36A3 SLC38A6 SLC38A3	7.49e-05	83	54	4	GO:0015101
GeneOntologyMolecularFunction	L-glutamine transmembrane transporter activity	SLC38A6 SLC38A3	2.55e-04	9	54	2	GO:0015186
GeneOntologyMolecularFunction	L-alanine transmembrane transporter activity	SLC36A3 SLC38A3	2.55e-04	9	54	2	GO:0015180
GeneOntologyMolecularFunction	active transmembrane transporter activity	ABCC8 SLC7A5 SLC36A3 ABCC12 SLC13A3 ANKH SLC38A3	2.85e-04	477	54	7	GO:0022804
GeneOntologyMolecularFunction	aromatic amino acid transmembrane transporter activity	SLC7A5 SLC38A3	5.49e-04	13	54	2	GO:0015173
GeneOntologyMolecularFunction	G protein-coupled receptor activity	CYSLTR2 OR51Q1 OR13C8 OR10K2 GPR87 ADGRF5 TAS2R39 SSTR3 F2RL1	5.55e-04	884	54	9	GO:0004930
GeneOntologyMolecularFunction	ATP transmembrane transporter activity	PANX1 ANKH	6.40e-04	14	54	2	GO:0005347
GeneOntologyMolecularFunction	alanine transmembrane transporter activity	SLC36A3 SLC38A3	8.41e-04	16	54	2	GO:0022858
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	CYSLTR2 OR51Q1 OR13C8 ABCC8 OR10K2 GPR87 ADGRF5 TAS2R39 SSTR3 F2RL1 SORL1	8.50e-04	1353	54	11	GO:0004888
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	KCNA2 SLC31A2 ABCC8 SLC36A3 PANX1 SLC13A3 ANKH SLC38A3	9.21e-04	758	54	8	GO:0015318
GeneOntologyMolecularFunction	adenylate cyclase activity	ADCY5 ADCY7	1.07e-03	18	54	2	GO:0004016
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC7A5 SLC36A3 SLC13A3 ANKH SLC38A3	1.21e-03	296	54	5	GO:0015291
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	KCNA2 SLC31A2 ABCC8 TPTE2 SLC36A3 PANX1 SLC13A3 SLC38A3	1.23e-03	793	54	8	GO:0015075
GeneOntologyMolecularFunction	acidic amino acid transmembrane transporter activity	SLC13A3 SLC38A6	1.32e-03	20	54	2	GO:0015172
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	KCNA2 SLC31A2 ABCC8 SLC36A3 PANX1 SLC13A3 SLC38A3	1.43e-03	627	54	7	GO:0022890
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	KCNA2 SLC31A2 ABCC8 PANX1 SLC13A3 SLC38A3	1.55e-03	465	54	6	GO:0046873
GeneOntologyMolecularFunction	purine ribonucleotide transmembrane transporter activity	PANX1 ANKH	1.75e-03	23	54	2	GO:0005346
GeneOntologyMolecularFunction	cyclase activity	ADCY5 ADCY7	1.91e-03	24	54	2	GO:0009975
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	KCNA2 SLC31A2 ABCC8 SLC36A3 PANX1 SLC13A3 SLC38A3	1.98e-03	664	54	7	GO:0008324
GeneOntologyMolecularFunction	phosphorus-oxygen lyase activity	ADCY5 ADCY7	2.07e-03	25	54	2	GO:0016849
GeneOntologyMolecularFunction	adenine nucleotide transmembrane transporter activity	PANX1 ANKH	2.24e-03	26	54	2	GO:0000295
GeneOntologyMolecularFunction	amino acid:monoatomic cation symporter activity	SLC36A3 SLC38A3	2.78e-03	29	54	2	GO:0005416
GeneOntologyMolecularFunction	purine nucleotide transmembrane transporter activity	PANX1 ANKH	2.78e-03	29	54	2	GO:0015216
GeneOntologyMolecularFunction	nucleotide transmembrane transporter activity	PANX1 ANKH	3.59e-03	33	54	2	GO:0015215
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC36A3 SLC13A3 SLC38A3	4.10e-03	119	54	3	GO:0015294
GeneOntologyMolecularFunction	neuropeptide binding	SSTR3 SORL1	4.50e-03	37	54	2	GO:0042923
GeneOntologyMolecularFunction	organophosphate ester transmembrane transporter activity	PANX1 ANKH	4.99e-03	39	54	2	GO:0015605
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	CYSLTR2 SSTR3 F2RL1	5.59e-03	133	54	3	GO:0008528
GeneOntologyMolecularFunction	amide transmembrane transporter activity	SLC13A3 SLC38A3	5.77e-03	42	54	2	GO:0042887
GeneOntologyMolecularFunction	peptide receptor activity	CYSLTR2 SSTR3 F2RL1	6.44e-03	140	54	3	GO:0001653
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCC8 ABCC12	7.78e-03	49	54	2	GO:0140359
GeneOntologyMolecularFunction	symporter activity	SLC36A3 SLC13A3 SLC38A3	7.79e-03	150	54	3	GO:0015293
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	ABCC8 SLC36A3 SLC13A3 SLC38A3	8.86e-03	301	54	4	GO:0022853
GeneOntologyMolecularFunction	carbohydrate derivative transmembrane transporter activity	PANX1 ANKH	1.11e-02	59	54	2	GO:1901505
GeneOntologyMolecularFunction	nucleobase-containing compound transmembrane transporter activity	PANX1 ANKH	1.11e-02	59	54	2	GO:0015932
GeneOntologyBiologicalProcess	amino acid transmembrane transport	SLC7A5 SLC36A3 SLC13A3 SLC7A14 SLC38A6 SLC38A3	7.03e-07	120	54	6	GO:0003333
GeneOntologyBiologicalProcess	amino acid transport	ABCC8 SLC7A5 SLC36A3 SLC13A3 SLC7A14 SLC38A6 SLC38A3	7.37e-07	195	54	7	GO:0006865
GeneOntologyBiologicalProcess	organic anion transport	ABCC8 SLC7A5 SLC36A3 PANX1 SLC13A3 ANKH SLC7A14 SLC38A6 SLC38A3	6.88e-06	515	54	9	GO:0015711
GeneOntologyBiologicalProcess	L-amino acid transport	ABCC8 SLC7A5 SLC36A3 SLC38A6 SLC38A3	9.25e-06	108	54	5	GO:0015807
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	CYSLTR2 PDE3A OR51Q1 OR13C8 OR10K2 GPR87 ADGRF5 PLCB4 TAS2R39 SSTR3 F2RL1 ADCY5 ADCY7 SORL1	9.81e-06	1395	54	14	GO:0007186
GeneOntologyBiologicalProcess	alanine transport	SLC7A5 SLC36A3 SLC38A3	1.35e-05	18	54	3	GO:0032328
GeneOntologyBiologicalProcess	neutral amino acid transport	SLC7A5 SLC36A3 SLC38A6 SLC38A3	1.84e-05	60	54	4	GO:0015804
GeneOntologyBiologicalProcess	L-histidine transport	SLC7A5 SLC38A3	4.02e-05	4	54	2	GO:1902024
GeneOntologyBiologicalProcess	histidine transport	SLC7A5 SLC38A3	4.02e-05	4	54	2	GO:0015817
GeneOntologyBiologicalProcess	negative regulation of amyloid-beta formation	RTN3 RTN2 SORL1	5.91e-05	29	54	3	GO:1902430
GeneOntologyBiologicalProcess	carboxylic acid transmembrane transport	SLC7A5 SLC36A3 SLC13A3 SLC38A6 SLC38A3	6.70e-05	163	54	5	GO:1905039
GeneOntologyBiologicalProcess	organic acid transmembrane transport	SLC7A5 SLC36A3 SLC13A3 SLC38A6 SLC38A3	7.52e-05	167	54	5	GO:1903825
GeneOntologyBiologicalProcess	negative regulation of amyloid precursor protein catabolic process	RTN3 RTN2 SORL1	7.97e-05	32	54	3	GO:1902992
GeneOntologyBiologicalProcess	carboxylic acid transport	ABCC8 SLC7A5 SLC36A3 SLC13A3 SLC7A14 SLC38A6 SLC38A3	9.22e-05	410	54	7	GO:0046942
GeneOntologyBiologicalProcess	organic acid transport	ABCC8 SLC7A5 SLC36A3 SLC13A3 SLC7A14 SLC38A6 SLC38A3	9.51e-05	412	54	7	GO:0015849
GeneOntologyBiologicalProcess	negative regulation of amide metabolic process	RTN3 RTN2 SORL1	9.58e-05	34	54	3	GO:0034249
GeneOntologyBiologicalProcess	leukocyte chemotaxis involved in inflammatory response	SLAMF8 NINJ1	1.86e-04	8	54	2	GO:0002232
GeneOntologyBiologicalProcess	copper ion import	SLC31A2 STEAP1B	2.39e-04	9	54	2	GO:0015677
GeneOntologyBiologicalProcess	vascular process in circulatory system	PDE3A ABCC8 SLC7A5 SLC13A3 F2RL1 SLC38A3	2.71e-04	344	54	6	GO:0003018
GeneOntologyBiologicalProcess	glutamine transport	SLC38A6 SLC38A3	2.99e-04	10	54	2	GO:0006868
GeneOntologyBiologicalProcess	regulation of amyloid-beta formation	RTN3 RTN2 SORL1	3.05e-04	50	54	3	GO:1902003
GeneOntologyBiologicalProcess	cAMP biosynthetic process	ADCY5 ADCY7	3.64e-04	11	54	2	GO:0006171
GeneOntologyBiologicalProcess	L-alanine transport	SLC36A3 SLC38A3	3.64e-04	11	54	2	GO:0015808
GeneOntologyBiologicalProcess	regulation of amyloid precursor protein catabolic process	RTN3 RTN2 SORL1	4.97e-04	59	54	3	GO:1902991
GeneOntologyBiologicalProcess	amyloid-beta formation	RTN3 RTN2 SORL1	4.97e-04	59	54	3	GO:0034205
GeneOntologyBiologicalProcess	aromatic amino acid transport	SLC7A5 SLC38A3	5.15e-04	13	54	2	GO:0015801
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	KCNA2 SLC31A2 ABCC8 TPTE2 SLC36A3 PANX1 SLC13A3 PLCB4 STEAP1B ATP10A	5.56e-04	1115	54	10	GO:0034220
GeneOntologyBiologicalProcess	regulation of glial cell proliferation	CYSLTR2 ABCC8 SLC7A5	5.75e-04	62	54	3	GO:0060251
GeneOntologyBiologicalProcess	positive regulation of toll-like receptor 4 signaling pathway	NINJ1 F2RL1	6.91e-04	15	54	2	GO:0034145
GeneOntologyBiologicalProcess	monoatomic ion transport	KCNA2 SLC31A2 ABCC8 TPTE2 SLC36A3 PANX1 SLC13A3 PLCB4 STEAP1B ATP10A SLC38A3	7.38e-04	1374	54	11	GO:0006811
GeneOntologyBiologicalProcess	amyloid-beta metabolic process	RTN3 RTN2 SORL1	7.87e-04	69	54	3	GO:0050435
GeneOntologyCellularComponent	endoplasmic reticulum membrane	KCNA2 CYP2D6 TPTE2 CANX DNAJC18 RTN3 TMEM39B ABCC12 PANX1 APOB POMT1 ALG6 ATP10A RTN2 SORL1	6.00e-07	1293	54	15	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	KCNA2 CYP2D6 TPTE2 CANX DNAJC18 RTN3 TMEM39B ABCC12 PANX1 APOB POMT1 ALG6 ATP10A RTN2 SORL1	6.37e-07	1299	54	15	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	KCNA2 CYP2D6 TPTE2 CANX DNAJC18 RTN3 TMEM39B ABCC12 PANX1 APOB POMT1 ALG6 ATP10A RTN2 SORL1	8.34e-07	1327	54	15	GO:0042175
GeneOntologyCellularComponent	smooth endoplasmic reticulum	CANX APOB PLCB4	2.29e-04	46	54	3	GO:0005790
Domain	Aa_trans	SLC36A3 SLC38A6 SLC38A3	1.51e-05	17	54	3	PF01490
Domain	AA_transpt_TM	SLC36A3 SLC38A6 SLC38A3	1.51e-05	17	54	3	IPR013057
Domain	RETICULON	RTN3 RTN2	8.16e-05	5	54	2	PS50845
Domain	Adcy_conserved_dom	ADCY5 ADCY7	1.22e-04	6	54	2	IPR009398
Domain	DUF1053	ADCY5 ADCY7	1.22e-04	6	54	2	PF06327
Domain	Reticulon	RTN3 RTN2	1.71e-04	7	54	2	PF02453
Domain	AC_N	ADCY5 ADCY7	2.27e-04	8	54	2	IPR032628
Domain	Adcy	ADCY5 ADCY7	2.27e-04	8	54	2	IPR030672
Domain	Reticulon	RTN3 RTN2	2.27e-04	8	54	2	IPR003388
Domain	AC_N	ADCY5 ADCY7	2.27e-04	8	54	2	PF16214
Domain	AA_permease_2	SLC7A5 SLC7A14	6.27e-04	13	54	2	PF13520
Domain	AA/rel_permease1	SLC7A5 SLC7A14	6.27e-04	13	54	2	IPR002293
Domain	A/G_cyclase_CS	ADCY5 ADCY7	1.09e-03	17	54	2	IPR018297
Domain	Nucleotide_cyclase	ADCY5 ADCY7	1.22e-03	18	54	2	IPR029787
Domain	-	ADCY5 ADCY7	1.22e-03	18	54	2	3.30.70.1230
Domain	GUANYLATE_CYCLASE_1	ADCY5 ADCY7	1.36e-03	19	54	2	PS00452
Domain	Guanylate_cyc	ADCY5 ADCY7	1.36e-03	19	54	2	PF00211
Domain	GUANYLATE_CYCLASE_2	ADCY5 ADCY7	1.36e-03	19	54	2	PS50125
Domain	A/G_cyclase	ADCY5 ADCY7	1.36e-03	19	54	2	IPR001054
Domain	CYCc	ADCY5 ADCY7	1.36e-03	19	54	2	SM00044
Domain	AA-permease/SLC12A_dom	SLC7A5 SLC7A14	1.83e-03	22	54	2	IPR004841
Domain	AA_permease	SLC7A5 SLC7A14	1.83e-03	22	54	2	PF00324
Domain	ABC_membrane	ABCC8 ABCC12	2.17e-03	24	54	2	PF00664
Domain	ABC_TM1F	ABCC8 ABCC12	2.96e-03	28	54	2	PS50929
Domain	ABC1_TM_dom	ABCC8 ABCC12	2.96e-03	28	54	2	IPR011527
Domain	GPCR_Rhodpsn_7TM	CYSLTR2 OR51Q1 OR13C8 OR10K2 GPR87 SSTR3 F2RL1	3.03e-03	670	54	7	IPR017452
Domain	7tm_1	CYSLTR2 OR51Q1 OR13C8 OR10K2 GPR87 SSTR3 F2RL1	3.21e-03	677	54	7	PF00001
Domain	G_PROTEIN_RECEP_F1_1	CYSLTR2 OR51Q1 OR13C8 OR10K2 GPR87 SSTR3 F2RL1	3.43e-03	685	54	7	PS00237
Domain	G_PROTEIN_RECEP_F1_2	CYSLTR2 OR51Q1 OR13C8 OR10K2 GPR87 SSTR3 F2RL1	3.60e-03	691	54	7	PS50262
Domain	GPCR_Rhodpsn	CYSLTR2 OR51Q1 OR13C8 OR10K2 GPR87 SSTR3 F2RL1	3.62e-03	692	54	7	IPR000276
Domain	ABC_transporter_CS	ABCC8 ABCC12	6.56e-03	42	54	2	IPR017871
Domain	ABC_tran	ABCC8 ABCC12	8.50e-03	48	54	2	PF00005
Domain	ABC_TRANSPORTER_2	ABCC8 ABCC12	8.50e-03	48	54	2	PS50893
Pathway	REACTOME_G_PROTEIN_MEDIATED_EVENTS	PLCB4 ADCY5 ADCY7	1.80e-04	39	40	3	MM14496
Pathway	REACTOME_NEURONAL_SYSTEM	KCNA2 ABCC8 RTN3 PANX1 ADCY5 ADCY7	3.34e-04	335	40	6	MM14503
Pathway	REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY	ADCY5 ADCY7	3.48e-04	10	40	2	M19522
Pathway	REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY	ADCY5 ADCY7	3.48e-04	10	40	2	MM14668
Pathway	REACTOME_SIGNALING_BY_GPCR	CYSLTR2 PDE3A PLCB4 TAS2R39 SSTR3 F2RL1 ADCY5 ADCY7	3.89e-04	646	40	8	MM14962
Pathway	REACTOME_G_PROTEIN_MEDIATED_EVENTS	PLCB4 ADCY5 ADCY7	4.75e-04	54	40	3	M26911
Pathway	WP_PHOSPHODIESTERASES_IN_NEURONAL_FUNCTION	PDE3A ADCY5 ADCY7	5.01e-04	55	40	3	M39763
Pathway	REACTOME_SIGNALING_BY_GPCR	CYSLTR2 PDE3A PLCB4 TAS2R39 SSTR3 F2RL1 ADCY5 ADCY7	6.77e-04	702	40	8	M746
Pathway	REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY	ADCY5 ADCY7	6.99e-04	14	40	2	MM14669
Pathway	REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY	ADCY5 ADCY7	6.99e-04	14	40	2	M750
Pathway	PID_ENDOTHELIN_PATHWAY	CYSLTR2 ADCY5 ADCY7	7.47e-04	63	40	3	M8
Pathway	KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY	ADCY5 ADCY7	8.05e-04	15	40	2	M47794
Pathway	PID_LPA4_PATHWAY	ADCY5 ADCY7	8.05e-04	15	40	2	M56
Pathway	KEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY	ADCY5 ADCY7	8.05e-04	15	40	2	M47504
Pathway	WP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE	ADCY5 ADCY7	9.19e-04	16	40	2	M39849
Pathway	KEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY	ADCY5 ADCY7	9.19e-04	16	40	2	M47645
Pathway	KEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY	ADCY5 ADCY7	9.19e-04	16	40	2	M47650
Pathway	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	ADCY5 ADCY7	9.19e-04	16	40	2	MM14492
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC7A5 SLC13A3 APOB ATP10A ANKH ADCY5 SLC38A3 ADCY7	9.22e-04	736	40	8	M27287
Pathway	REACTOME_NEURONAL_SYSTEM	KCNA2 ABCC8 RTN3 PANX1 ADCY5 ADCY7	9.81e-04	411	40	6	M735
Pathway	REACTOME_G_ALPHA_S_SIGNALLING_EVENTS	CYSLTR2 PDE3A ADCY5 ADCY7	9.90e-04	157	40	4	M4904
Pathway	REACTOME_PKA_ACTIVATION_IN_GLUCAGON_SIGNALLING	ADCY5 ADCY7	1.04e-03	17	40	2	M26995
Pathway	KEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY	ADCY5 ADCY7	1.04e-03	17	40	2	M47544
Pathway	REACTOME_OPIOID_SIGNALLING	PLCB4 ADCY5 ADCY7	1.06e-03	71	40	3	MM14491
Pathway	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	PLCB4 TAS2R39 SSTR3 ADCY5 ADCY7	1.28e-03	289	40	5	MM15057
Pathway	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	ADCY5 ADCY7	1.44e-03	20	40	2	M759
Pathway	KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION	PDE3A ADCY5 ADCY7	1.78e-03	85	40	3	M3578
Pathway	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	PLCB4 TAS2R39 SSTR3 ADCY5 ADCY7	1.84e-03	314	40	5	M600
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY	ADCY5 ADCY7	2.08e-03	24	40	2	M47520
Pathway	KEGG_GAP_JUNCTION	PLCB4 ADCY5 ADCY7	2.10e-03	90	40	3	M4013
Pathway	REACTOME_OPIOID_SIGNALLING	PLCB4 ADCY5 ADCY7	2.10e-03	90	40	3	M6467
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAI_AC_PKA_SIGNALING_PATHWAY	ADCY5 ADCY7	2.44e-03	26	40	2	M47553
Pathway	REACTOME_CA_DEPENDENT_EVENTS	ADCY5 ADCY7	2.44e-03	26	40	2	MM14495
Pathway	KEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY	ADCY5 ADCY7	2.63e-03	27	40	2	M47518
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_RASD1_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY	ADCY5 ADCY7	2.63e-03	27	40	2	M47519
Pathway	KEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY	ADCY5 ADCY7	2.83e-03	28	40	2	M47647
Pathway	KEGG_MELANOGENESIS	PLCB4 ADCY5 ADCY7	2.91e-03	101	40	3	M7761
Pathway	KEGG_GNRH_SIGNALING_PATHWAY	PLCB4 ADCY5 ADCY7	2.91e-03	101	40	3	M1979
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_ACTH_CORTISOL_SIGNALING_PATHWAY	ADCY5 ADCY7	3.04e-03	29	40	2	M47515
Pathway	KEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY	ADCY5 ADCY7	3.04e-03	29	40	2	M47627
Pathway	KEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY	ADCY5 ADCY7	3.47e-03	31	40	2	M47507
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	ABCC8 ADCY5 ADCY7	3.52e-03	108	40	3	M17034
Pathway	REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE	SLC7A5 SLC38A3	3.69e-03	32	40	2	MM14957
Pathway	KEGG_MEDICUS_REFERENCE_ACTH_CORTISOL_SIGNALING_PATHWAY	ADCY5 ADCY7	3.69e-03	32	40	2	M47506
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	ADCY5 ADCY7	3.92e-03	33	40	2	MM15058
Pathway	REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE	SLC7A5 SLC38A3	3.92e-03	33	40	2	M188
Pathway	REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION	ADCY5 ADCY7	3.92e-03	33	40	2	M11575
Pathway	KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION	PLCB4 ADCY5 ADCY7	4.19e-03	115	40	3	M9387
Pathway	KEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY	ADCY5 ADCY7	4.40e-03	35	40	2	M47969
Pathway	REACTOME_CA_DEPENDENT_EVENTS	ADCY5 ADCY7	4.91e-03	37	40	2	M749
Pubmed	Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects.	SLC36A3 SLC38A6 SLC38A3	1.59e-06	15	54	3	23506890
Pubmed	Slc7a5 regulates Kv1.2 channels and modifies functional outcomes of epilepsy-linked channel mutations.	KCNA2 SLC7A5	2.37e-06	2	54	2	30356053
Pubmed	Proteasome-mediated degradation of apolipoprotein B targets both nascent peptides cotranslationally before translocation and full-length apolipoprotein B after translocation into the endoplasmic reticulum.	CANX APOB	2.37e-06	2	54	2	9765244
Pubmed	A role for palmitoylation in the quality control, assembly and secretion of apolipoprotein B.	CANX APOB	2.37e-06	2	54	2	14498830
Pubmed	Recently reported familial hypercholesterolemia-related mutations from cases in the Middle East and North Africa region.	APOB SORL1	7.09e-06	3	54	2	30694837
Pubmed	A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family.	RTN3 RTN2	1.42e-05	4	54	2	12832288
Pubmed	Expression of the murine Pomt1 gene in both the developing brain and adult muscle tissues and its relationship with clinical aspects of Walker-Warburg syndrome.	CANX POMT1	1.42e-05	4	54	2	17456771
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	KCNA2 TPRG1L TNC CANX RTN3 ADCY5	1.63e-05	347	54	6	17114649
Pubmed	Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation.	RTN3 RTN2	2.36e-05	5	54	2	15286784
Pubmed	Identification and characterization of TMEM33 as a reticulon-binding protein.	RTN3 RTN2	3.54e-05	6	54	2	25612671
Pubmed	Mutations of GNAQ, GNA11, SF3B1, EIF1AX, PLCB4 and CYSLTR in Uveal Melanoma in Chinese Patients.	CYSLTR2 PLCB4	3.54e-05	6	54	2	31614358
Pubmed	Coexistence within one cell of microvillous and ciliary phototransductions across M1- through M6-IpRGCs.	PLCB4 ADCY7	4.94e-05	7	54	2	38109525
Pubmed	Intracellular lipidation of newly synthesized apolipoprotein A-I in primary murine hepatocytes.	CANX APOB	4.94e-05	7	54	2	16204232
Pubmed	Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.	SLAMF8 RTN3 PRRG3 ADGRF5 PANX1 POMT1	5.39e-05	430	54	6	16303743
Pubmed	Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms.	ADCY5 ADCY7	8.46e-05	9	54	2	12503609
Pubmed	Role of the calcium modulated cyclases in the development of the retinal projections.	ADCY5 ADCY7	8.46e-05	9	54	2	17229090
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	SNX14 CANX DNAJC18 RTN3 SLC7A5 POMT1 ALG6 PLS3 SORL1	8.89e-05	1201	54	9	35696571
Pubmed	Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.	CANX SLC7A5 APOB POMT1 F2RL1	9.71e-05	296	54	5	34186245
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	CYSLTR2 SLC31A2 ABCC8 CANX RTN3 PANX1 F2RL1	9.85e-05	697	54	7	28298427
Pubmed	Purification and characterization of a soluble form of mammalian adenylyl cyclase.	ADCY5 ADCY7	1.06e-04	10	54	2	8663304
Pubmed	Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain.	ADCY5 ADCY7	1.06e-04	10	54	2	16615126
Pubmed	Mutations in the Cacnl1a4 calcium channel gene are associated with seizures, cerebellar degeneration, and ataxia in tottering and leaner mutant mice.	PEG3 ADCY7	1.06e-04	10	54	2	9060410
Pubmed	Mechanism of human immunodeficiency virus-induced complement expression in astrocytes and neurons.	ADCY5 ADCY7	1.06e-04	10	54	2	11884542
Pubmed	Involvement of adenylate cyclase and p70(S6)-kinase activation in IL-10 up-regulation in human monocytes by gp41 envelope protein of human immunodeficiency virus type 1.	ADCY5 ADCY7	1.29e-04	11	54	2	10089566
Pubmed	gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP generation, Ig production, and B-cell receptor expression.	ADCY5 ADCY7	1.29e-04	11	54	2	10808179
Pubmed	Human homology and candidate genes for the Dominant megacolon locus, a mouse model of Hirschsprung disease.	CYP2D6 SSTR3	1.55e-04	12	54	2	9027489
Pubmed	Expression of adenylyl cyclase mRNAs in the denervated and in the developing mouse skeletal muscle.	ADCY5 ADCY7	1.55e-04	12	54	2	9611134
Pubmed	HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones.	ADCY5 ADCY7	1.55e-04	12	54	2	10807185
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	SLC31A2 TNC GPR87 SLC13A3 POMT1 PLS3 SLC38A6 SLC38A3 ADCY7	1.55e-04	1293	54	9	15342556
Pubmed	Reticulons 1 and 3 are essential for axonal growth and synaptic maintenance associated with intellectual development.	RTN3 RTN2	1.83e-04	13	54	2	37228035
Pubmed	ERCC1-XPF cooperates with CTCF and cohesin to facilitate the developmental silencing of imprinted genes.	PEG3 ATP10A	2.13e-04	14	54	2	28368372
Pubmed	Isoforms of mammalian adenylyl cyclase: multiplicities of signaling.	ADCY5 ADCY7	2.13e-04	14	54	2	14993377
Pubmed	Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?	CYP2D6 ABCC8 APOB SSTR3	2.29e-04	192	54	4	20602615
Pubmed	Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.	ADCY5 ADCY7	2.80e-04	16	54	2	17567809
Pubmed	Intestinal SURF4 is essential for apolipoprotein transport and lipoprotein secretion.	CANX APOB	2.80e-04	16	54	2	38042368
Pubmed	PTEN identified as important risk factor of chronic obstructive pulmonary disease.	CYP2D6 DNAJC18 NINJ1 APOB SSTR3	2.87e-04	374	54	5	19625176
Pubmed	Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.	CYP2D6 DNAJC18 NINJ1 APOB SSTR3	3.17e-04	382	54	5	19170196
Pubmed	Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.	KCNA2 SLC7A5 SSTR3 ANKH SLC38A3	4.13e-04	405	54	5	38187761
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	CC2D2A POMT1 STRA6 SLC7A14	4.77e-04	233	54	4	32290105
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	UTP15 TNC TPTE2 CANX APOB	4.88e-04	420	54	5	28065597
Pubmed	Genetic susceptibility to distinct bladder cancer subphenotypes.	CYP2D6 DNAJC18 NINJ1 APOB SSTR3	4.93e-04	421	54	5	19692168
Pubmed	Blood-Brain Barrier: From Physiology to Disease and Back.	SLC7A5 SLC13A3 SLC38A3	5.93e-04	105	54	3	30280653
Pubmed	Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.	PDE3A SMG6	6.39e-04	24	54	2	19584346
Pubmed	ZFP57 dictates allelic expression switch of target imprinted genes.	PEG3 ATP10A	6.94e-04	25	54	2	33500348
Pubmed	Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development.	CANX SLC7A5 APOB	7.34e-04	113	54	3	30352685
Pubmed	Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.	CC2D2A PLS3	8.72e-04	28	54	2	33953184
Pubmed	Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response.	CYP2D6 APOB	1.07e-03	31	54	2	20031551
Pubmed	Amino acid transport across mammalian intestinal and renal epithelia.	SLC7A5 SLC38A3	1.07e-03	31	54	2	18195088
Pubmed	Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits.	FAT3 ANKH	1.21e-03	33	54	2	24204828
Pubmed	Microphthalmia/Anophthalmia/Coloboma Spectrum – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	POMT1 STRA6	1.29e-03	34	54	2	20301552
Pubmed	Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC.	EIF2B5 SLC7A5	1.44e-03	36	54	2	16097034
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	UTP15 CANX EIF2B5 CC2D2A RTN3 SLC7A5 APOB PLS3	1.51e-03	1425	54	8	30948266
Interaction	CHRNB2 interactions	CANX DNAJC18 TMEM39B PANX1 POMT1	6.16e-06	103	51	5	int:CHRNB2
Interaction	B4GAT1 interactions	CANX TMEM39B APOB POMT1 F2RL1	8.50e-06	110	51	5	int:B4GAT1
Interaction	KCNA2 interactions	SNX14 KCNA2 DNAJC18 TMEM39B SSTR3	1.58e-05	125	51	5	int:KCNA2
Interaction	ATP1B3 interactions	CANX RTN3 SLC7A5 POMT1 F2RL1 RTN2	2.49e-05	231	51	6	int:ATP1B3
Interaction	PDE10A interactions	PDE3A SLC7A5 SSTR3	3.81e-05	26	51	3	int:PDE10A
Interaction	ADCY9 interactions	CANX DNAJC18 PANX1 SSTR3 ADCY7	4.06e-05	152	51	5	int:ADCY9
Interaction	C1orf43 interactions	PDE3A KCNA2 CANX PANX1	5.24e-05	81	51	4	int:C1orf43
Interaction	GABRG2 interactions	CANX DNAJC18 SSTR3	8.64e-05	34	51	3	int:GABRG2
GeneFamily	Solute carriers	SLC31A2 SLC7A5 SLC36A3 SLC13A3 SLC7A14 SLC38A6 SLC38A3	3.14e-05	395	42	7	752
GeneFamily	Adenylate cyclases\|Deafness associated genes	ADCY5 ADCY7	2.34e-04	10	42	2	53
GeneFamily	ATP binding cassette subfamily C	ABCC8 ABCC12	4.04e-04	13	42	2	807
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	TNC FAT3 PLCB4 ATP10A PLS3 ADCY5	9.16e-08	183	54	6	818fd886e0188091310825f9145fa53328f2c979
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	PDE3A TNC FAT3 PLCB4 ATP10A PLS3	1.07e-07	188	54	6	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	CYSLTR2 PDE3A TNC FAT3 ADGRF5	3.07e-06	186	54	5	cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	PDE3A TNC PLCB4 PLS3 ADCY5	3.15e-06	187	54	5	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	TNC FAT3 PLCB4 ATP10A PLS3	3.32e-06	189	54	5	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	facs-Pancreas-Endocrine-3m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC8 CANX PEG3 ANKH SLC7A14	3.49e-06	191	54	5	b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A TNC FAT3 PEG3 ADCY5	3.49e-06	191	54	5	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC8 PEG3 SSTR3 ANKH SLC7A14	3.49e-06	191	54	5	f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	CYSLTR2 PDE3A TNC FAT3 ADGRF5	3.49e-06	191	54	5	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC8 PEG3 SSTR3 ANKH SLC7A14	3.49e-06	191	54	5	657297cd19d05a7e7bb74fc3a086fbd95f47aae4
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC8 PEG3 SSTR3 ANKH SLC7A14	3.59e-06	192	54	5	5b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell	droplet-Pancreas-Endocrine-18m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC8 CANX PEG3 SSTR3 SLC7A14	3.59e-06	192	54	5	4510aa262da8dcf7c944b3907a51aba5a9397a4e
ToppCell	facs-Pancreas-Endocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC8 PEG3 SSTR3 ANKH SLC7A14	3.68e-06	193	54	5	15c86e20b97b6983410b36d308cddff56d141c98
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CYSLTR2 PDE3A TNC SLC7A5 ADCY5	4.06e-06	197	54	5	3332b9b5bf78f0203ebbd94257a36e9054d896c3
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE3A TNC FAT3 PLCB4 ADCY5	4.06e-06	197	54	5	bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE3A TNC FAT3 PLCB4 ADCY5	4.37e-06	200	54	5	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Dendritic_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLAMF8 SLC7A5 PANX1 ADCY7	3.56e-05	153	54	4	c81a88d3f707487c511020d3960a1c41e706c6a0
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_2\|367C / Donor, Lineage, Cell class and subclass (all cells)	SLC31A2 CD207 ATP10A SLC38A6	3.84e-05	156	54	4	1a0e081284a99c1b345990775015b8a2fa469496
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D231\|Adult / Lineage, Cell type, age group and donor	PDE3A TNC PLCB4 ADCY5	4.04e-05	158	54	4	8d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	TNC FAT3 ATP10A PLS3	4.24e-05	160	54	4	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	TNC FAT3 ATP10A PLS3	4.35e-05	161	54	4	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ADGRF5 PLCB4 ATP10A	4.78e-05	165	54	4	4f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ADGRF5 PLCB4 ATP10A	4.78e-05	165	54	4	cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-cDC2\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYSLTR2 SLC31A2 CD207 ATP10A	5.01e-05	167	54	4	1bd0aa7a3c8649f342bb856cf861c4c5984ad889
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CYSLTR2 PDE3A ABCC8 ATP10A	5.01e-05	167	54	4	b4ef07117d14da3d5fbced949e4dfcb01c392295
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CYSLTR2 PDE3A ABCC8 ATP10A	5.01e-05	167	54	4	94fc7df7ca55cd722a8dbd153201a29891217473
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CYSLTR2 PDE3A ABCC8 ATP10A	5.01e-05	167	54	4	eff3723fe60755272eca237459165e436e919ece
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A FAT3 PLCB4 ADCY5	5.37e-05	170	54	4	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF8 KCNA2 NINJ1 SLC13A3	5.37e-05	170	54	4	067657ca7fcf5a0ffbd168b5c4609a30ca508f22
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYSLTR2 SLC31A2 FAT3 ATP10A	5.62e-05	172	54	4	c8ea80042faf923b08ff03d73100533d521d73ef
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC7A5 ADGRF5 STRA6 ATP10A	5.62e-05	172	54	4	c3a99828838af3b85c8c885d69cc8018f55ced50
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	PDE3A TNC PLCB4 ADCY5	5.62e-05	172	54	4	c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-regulatory_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYSLTR2 PANX1 F2RL1 SLC7A14	5.62e-05	172	54	4	ce444463f69bbb05c933615a0f1f43ddde3eee1c
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-Regulatory_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYSLTR2 PANX1 F2RL1 SLC7A14	5.62e-05	172	54	4	2c993a93ac91dcf6061eec001f51f8cccb6ee264
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	PDE3A TNC PLCB4 ADCY5	5.75e-05	173	54	4	a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PDE3A FAT3 PLCB4 ADCY5	5.75e-05	173	54	4	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	Bronchial_Brush-Epithelial-Ionocytes\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	FAT3 ADGRF5 ADCY5 SLC38A3	5.75e-05	173	54	4	e1de849dcd96063136bdac87e050ddbd55cabdcc
ToppCell	Bronchial_Brush-Epithelial-Ionocytes\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	FAT3 ADGRF5 ADCY5 SLC38A3	5.75e-05	173	54	4	f2a8f4918c1fb68d98bc3f33cd624de0f0f11e06
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYSLTR2 PANX1 F2RL1 SLC7A14	5.88e-05	174	54	4	33386750842c47ad7e7286d0f26a556da1a2de02
ToppCell	Bronchial_Biopsy-Epithelial-Ionocytes\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	FAT3 ADGRF5 APOB ADCY5	5.88e-05	174	54	4	7e7b13de916cd4fa0fa6fb06e6b4942877afa9fb
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-regulatory_T_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYSLTR2 PANX1 F2RL1 SLC7A14	5.88e-05	174	54	4	9344d4e76d7d9429aea87d3c0b98246200d16014
ToppCell	wk_20-22-Hematologic-Myeloid-CXCL9+_Mac\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SLAMF8 CYSLTR2 SLC31A2 NINJ1	6.01e-05	175	54	4	48f5bdbfc1ba40c3fb6411f12a69e61da2138296
ToppCell	Bronchial_Biopsy-Epithelial-Ionocytes\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	FAT3 ADGRF5 APOB ADCY5	6.01e-05	175	54	4	13b8f7dc38c90b74d4a20a84a8705d8e2ec244f6
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A5 ATP10A ANKH SORL1	6.14e-05	176	54	4	ea27e18407b8a13e8212830da859efeb8f158690
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells-T-cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC7A5 ATP10A ANKH SORL1	6.14e-05	176	54	4	bfbab3c5b738b3b0b1540f2059d0245fbd8c0031
ToppCell	LPS-IL1RA-Myeloid-Dendritic_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLAMF8 SLC7A5 ATP10A ADCY7	6.14e-05	176	54	4	f3bbe8c1a8d132705eac360cf531261271d84588
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ADGRF5 PLCB4 ATP10A	6.28e-05	177	54	4	a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ADGRF5 PLCB4 ATP10A	6.28e-05	177	54	4	3645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNC GPR87 STRA6 F2RL1	6.42e-05	178	54	4	445fb243d738a34794d66f34b92dde1f3ea6738e
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A TNC FAT3 PEG3	6.85e-05	181	54	4	9e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCell	COVID-19-Heart-Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CYSLTR2 PDE3A PLCB4 ADCY5	6.85e-05	181	54	4	33cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PDE3A TNC F2RL1 PLS3	7.00e-05	182	54	4	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A TNC FAT3 PEG3	7.15e-05	183	54	4	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ADGRF5 PLCB4 ATP10A	7.15e-05	183	54	4	667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	TNC FAT3 ATP10A PLS3	7.15e-05	183	54	4	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT3 ADGRF5 PLCB4 ADCY5	7.30e-05	184	54	4	a60802e11dcc5f932811260b08a95a32f60f6b19
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT3 ADGRF5 PLCB4 ADCY5	7.30e-05	184	54	4	39c230d32e4259bc784e0edfd9e2884c96898564
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC8 PEG3 STRA6 SLC7A14	7.30e-05	184	54	4	3da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT3 ADGRF5 PLCB4 ADCY5	7.30e-05	184	54	4	2a2fb691cc9414ef5b06c26239d2da03d6d7e5c2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ADGRF5 PLCB4 ATP10A	7.45e-05	185	54	4	7092436b4db90289516ed130ade596e3021cffaf
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC7A5 ADGRF5 ATP10A SLC38A3	7.45e-05	185	54	4	03df43e9c2ce4ec24ffed8e4e2993f94ba951c8b
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC7A5 ADGRF5 ATP10A SLC38A3	7.45e-05	185	54	4	dbdbd6593cd98550238519746bb45fbf0617550b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ADGRF5 PLCB4 ATP10A	7.45e-05	185	54	4	a8ca7819066d5297ef6966e7f3e2c9f8a7673fdc
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Endo\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC7A5 ADGRF5 ATP10A SLC38A3	7.45e-05	185	54	4	de2c24719946d5a37a982d816776cea7f3984c49
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A5 ADGRF5 STRA6 ATP10A	7.61e-05	186	54	4	ba6ba75218efc26371cea24ddbb0e9b3e3f421ac
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC7A5 ADGRF5 ATP10A SLC38A3	7.61e-05	186	54	4	422d24e3e1a9397bb7d5c7ef75de2fd7ae8e136d
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A5 ADGRF5 STRA6 ATP10A	7.61e-05	186	54	4	65e25a9dcef5fc71510aaf170e220deef5b2feb2
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC7A5 ADGRF5 ATP10A SLC38A3	7.61e-05	186	54	4	65da0666a10a59f8cc379589860a2e98fe487754
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC7A5 ADGRF5 ATP10A SLC38A3	7.61e-05	186	54	4	dc84fef1ca2f5d5d818b76a3321559e87d1c4a4d
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A5 ADGRF5 STRA6 ATP10A	7.61e-05	186	54	4	e4f1259725160719e5fd13d76e5a707efed70013
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ADGRF5 PLCB4 ATP10A	7.77e-05	187	54	4	ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ADGRF5 PLCB4 ATP10A	7.77e-05	187	54	4	48bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A TNC ABCC8 ATP10A	7.77e-05	187	54	4	15d6e158562d7d85af3ceaf955439b379c8fce81
ToppCell	droplet-Pancreas\|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC8 PEG3 SSTR3 SLC7A14	7.77e-05	187	54	4	5f4df092452d8672bda4059c794e099ba3f5a8fa
ToppCell	5'-Adult-LymphNode-Hematopoietic-Myeloid-Macrophages\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLAMF8 CYSLTR2 NINJ1 RTN2	7.77e-05	187	54	4	00930e407beaa337f72533a69f32d150faad8b9a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ADGRF5 PLCB4 ATP10A	7.77e-05	187	54	4	530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A TNC ABCC8 ATP10A	7.77e-05	187	54	4	f62074b631fd45ad299c69d71b09267b04d656ee
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ADGRF5 PLCB4 ATP10A	7.77e-05	187	54	4	958402fcc78f4c7a7d13d659d776f3817137975f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A TNC ABCC8 ATP10A	7.93e-05	188	54	4	32f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ABCC8 ATP10A ADCY5	8.10e-05	189	54	4	7fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ABCC8 ATP10A ADCY5	8.10e-05	189	54	4	06b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC31A2 TNC STRA6 F2RL1	8.10e-05	189	54	4	319e42f6e2322208de78bc666fb2c074707eb4da
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A TNC FAT3 ADCY5	8.10e-05	189	54	4	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	megakaryocytic-CD34+_Megakaryoblast\|World / Lineage and Cell class	PDE3A PLCB4 RTN2 PLS3	8.26e-05	190	54	4	1d19b2bd55789bf13e1386332f46c605973d6f8e
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC31A2 TNC STRA6 F2RL1	8.26e-05	190	54	4	050d6e0546954675b6adbfecb67854b1e09739d1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ADGRF5 PLCB4 ATP10A	8.26e-05	190	54	4	5681c211baeed4af82a2bbc13420f6a7b487581c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A TNC FAT3 ATP10A	8.26e-05	190	54	4	70c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC8 PEG3 SSTR3 SLC7A14	8.43e-05	191	54	4	fd01a206763dfb6d52cca67123571936b4a8e1a0
ToppCell	facs-Pancreas\|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC8 PEG3 SSTR3 SLC7A14	8.43e-05	191	54	4	d48e5f67d384226add7d7fb2a124954136e09a82
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ADGRF5 PLCB4 ATP10A	8.43e-05	191	54	4	7b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ADGRF5 PLCB4 ATP10A	8.43e-05	191	54	4	cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-Myeloid-cDC2\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLAMF8 CYSLTR2 SLC31A2 CD207	8.60e-05	192	54	4	90274b85f3d612b6a6d435860cd6d049ddeb1d96
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A5 ADGRF5 ATP10A PLS3	8.60e-05	192	54	4	9d53b42cdb537b30233cdfdc08052c8b13a1113f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ABCC8 ATP10A ADCY5	8.60e-05	192	54	4	bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC8 PEG3 SSTR3 SLC7A14	8.60e-05	192	54	4	1304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCell	droplet-Pancreas-Endocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC8 PEG3 SSTR3 SLC7A14	8.60e-05	192	54	4	0dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ABCC8 ATP10A ADCY5	8.60e-05	192	54	4	b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A5 ADGRF5 ATP10A PLS3	8.60e-05	192	54	4	042391162df2e3d0027688dd14163c4c6821afe0
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A5 ADGRF5 ATP10A SLC38A3	8.60e-05	192	54	4	9ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A5 ADGRF5 ATP10A PLS3	8.60e-05	192	54	4	71b0bfee0461ff64cef35881db3959c517e9731b
Drug	2-(aminomethyl)pyrrolidine	CYSLTR2 GPR87 PANX1 PLCB4 ADCY5 ADCY7	2.22e-06	161	54	6	CID000072032
Drug	lithium chromate	SNX14 SLC13A3 APOB PLS3 ADCY5 SLC38A3 ADCY7	6.14e-06	296	54	7	CID000026627
Drug	orthovanadate	PDE3A KCNA2 TNC ABCC8 SSTR3 PLS3 ADCY5 ADCY7	8.02e-06	435	54	8	CID000061672
Drug	AC1L1E2H	ABCC8 APOB ADCY5 ADCY7	8.81e-06	55	54	4	CID000002612
Drug	probenecid	PANX1 SLC13A3 ANKH ADCY5 ADCY7	1.09e-05	123	54	5	CID000004911
Drug	trequinsin	PDE3A PLCB4 ADCY5 ADCY7	1.09e-05	58	54	4	CID000005537
Drug	dobutamine	PDE3A EIF2B5 APOB ADCY5 ADCY7	2.03e-05	140	54	5	CID000036811
Drug	pyrophosphate	TPK1 GPR87 PLCB4 ALG6 ANKH ADCY5 SLC38A3 ADCY7 SMG6	2.11e-05	654	54	9	CID000001023
Drug	fenoldopam	PDE3A PLCB4 ADCY5 ADCY7	2.31e-05	70	54	4	CID000003340
Drug	octimibate	APOB ADCY5 ADCY7	2.80e-05	25	54	3	CID000065676
Drug	8-isoprostaglandin E1	PDE3A TNC APOB PLCB4 ADCY5 ADCY7	2.80e-05	251	54	6	CID000000214
Drug	glibenclamide	KCNA2 ABCC8 ABCC12 APOB F2RL1 ADCY5 ADCY7	3.18e-05	382	54	7	CID000003488
Drug	mepyramine	CYSLTR2 CYP2D6 ABCC8 ADCY5 ADCY7	3.21e-05	154	54	5	CID000004992
Drug	motapizone	PDE3A ADCY5 ADCY7	4.41e-05	29	54	3	CID000065819
Drug	papaverine	PDE3A ABCC8 PLCB4 ADCY5 ADCY7	6.07e-05	176	54	5	CID000004680
Drug	sodium	KCNA2 SLC7A5 SLC36A3 SLC13A3 ANKH SLC7A14 PLS3 ADCY5 SLC38A3 ADCY7	6.51e-05	944	54	10	CID000000923
Drug	cimetidine	CYP2D6 ABCC8 SLC13A3 ADCY5 ADCY7	6.58e-05	179	54	5	CID000002756
Drug	carbamazepine	CYP2D6 SLC13A3 APOB ADCY5 ADCY7	6.58e-05	179	54	5	CID000002554
Drug	tienilic acid	CYP2D6 SLC13A3 ADCY5 ADCY7	7.06e-05	93	54	4	CID000038409
Drug	glutamate	KCNA2 TNC SLC7A5 NINJ1 SLC13A3 PLCB4 PLS3 ADCY5 SLC38A3 ADCY7	7.62e-05	962	54	10	CID000000611
Drug	zardaverine	PDE3A ADCY5 ADCY7	7.82e-05	35	54	3	CID000005723
Drug	Sulfachloropyridazine [80-32-0]; Up 200; 14uM; MCF7; HT_HG-U133A	CD207 ADGRF5 SLC13A3 SSTR3 ANKH	1.08e-04	199	54	5	3944_UP
Drug	nickel sulfate	SLAMF8 SNX14 CANX SLC7A5 ADCY7	1.16e-04	202	54	5	CID000024586
Drug	Lopac-S-1316	SSTR3 ADCY5 ADCY7	1.17e-04	40	54	3	CID003086457
Drug	N6-(phenylisopropyl)adenosine	PDE3A ADCY5 ADCY7	1.26e-04	41	54	3	CID000034507
Drug	AC1L1I54	SSTR3 ADCY5 ADCY7	1.26e-04	41	54	3	CID000004426
Drug	Ro-1724	PDE3A PLCB4 ADCY5 ADCY7	1.35e-04	110	54	4	CID000005087
Drug	amrinone	PDE3A ADCY5 ADCY7	1.46e-04	43	54	3	CID000003698
Drug	AC1L1EV8	ADCY5 ADCY7	1.53e-04	8	54	2	CID000002964
Drug	aminophylline	PDE3A ADCY5 ADCY7	1.67e-04	45	54	3	CID000009433
Disease	hereditary spastic paraplegia 12 (implicated_via_orthology)	RTN3 RTN2	1.89e-05	4	53	2	DOID:0110765 (implicated_via_orthology)
Disease	Uveal melanoma	CYSLTR2 PLCB4	8.80e-05	8	53	2	C0220633
Disease	asthma (is_implicated_in)	CYSLTR2 CYP2D6 TNC F2RL1	1.84e-04	157	53	4	DOID:2841 (is_implicated_in)
Disease	homostachydrine measurement	SLC36A3 PLCB4	2.44e-04	13	53	2	EFO_0021164
Disease	myeloid white cell count	PDE3A SLC31A2 CANX ADGRF5 STEAP1B ADCY5 SMG6 SORL1	2.51e-04	937	53	8	EFO_0007988
Disease	Impaired cognition	EIF2B5 SORL1	2.84e-04	14	53	2	C0338656
Disease	Dystonia	TPK1 CYP2D6 ADCY5	5.04e-04	86	53	3	C0013421
Disease	visual epilepsy (biomarker_via_orthology)	ABCC8 ANKH SLC38A3	5.76e-04	90	53	3	DOID:11832 (biomarker_via_orthology)
Disease	glucose tolerance test	ABCC8 ADCY5	1.08e-03	27	53	2	EFO_0004307
Disease	colorectal adenocarcinoma (is_marker_for)	SLC7A5 STRA6	1.08e-03	27	53	2	DOID:0050861 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LESRKYILVVPLIVI	SMG6	1266	Q86US8
VLIADLLIYIPAVVL	ALG6	116	Q9Y672
LEPKVVLLTVALVAY	ADCY7	741	P51828
MLAIELIYVLIVEVP	ADCY5	936	O95622
VLIPISLYVSIEIVK	ATP10A	371	O60312
NIIDIVAIIPYFITL	KCNA2	256	P16389
VLLPLANVALIDYTL	EIF2B5	66	Q13144
ALVILQLYERIKVPV	PLS3	426	P13797
LLIIIVDPLLIVISY	OR51Q1	206	Q8NH59
VDPLLIVISYTLILK	OR51Q1	211	Q8NH59
VLGILLARYVEQILP	PDE3A	246	Q14432
LAIIISLPIVTLVYV	SLC7A5	276	Q01650
LSVINLVVYVLLAPV	PANX1	276	Q96RD7
DTIVLPVLYLIIFVA	GPR87	41	Q9BY21
IELLVLEQYLTIIPE	PEG3	86	Q9GZU2
FYVPLVVLISISLVL	NINJ1	76	Q92982
AVALLVIPVVLYLLF	POMT1	266	Q9Y6A1
LILLVTIPLYVVKQT	F2RL1	201	P55085
LLIDVVTYLVALIPE	APOB	406	P04114
IKLLVNIVRAYDIPV	CC2D2A	1041	Q9P2K1
LVPLAVIVAIFLLLV	CYP2D6	6	P10635
LVLLLLAVLYEGIKV	SLC31A2	31	O15432
ILLLPTYVGVEVLKV	FAT3	1891	Q8TDW7
VYILTVALPVFLVIL	CANX	486	P27824
LRIIVLIASLVVLPY	ANKH	406	Q9HCJ1
YSAFIQLLPVLVIVI	DNAJC18	226	Q9H819
ATIIIFLPVLAELAI	SLC13A3	486	Q8WWT9
VLAIPLLLILVSYVH	OR10K2	206	Q6IF99
VLVIPLLVISISYIF	OR13C8	206	Q8NGS7
ILAELLIFSVPIVYE	RTN3	981	O95197
SLLLAVYKTVPILEL	RTN2	281	O75298
LILAVLLAEYLIGII	TAS2R39	36	P59534
PVLINAAEIIIDIYL	UTP15	436	Q8TED0
VAAVVVPILFLILLS	SORL1	2136	Q92673
YLVILVSVTIILPLA	SLC38A3	191	Q99624
KVILPDLAVLRIAVY	PLCB4	761	Q15147
LIPLVYLVVCVVGLL	SSTR3	46	P32745
ALNIIIVLLAIYVPD	SLC38A6	376	Q8IZM9
LVILAAVFPAVLLVV	ABCC12	941	Q96J65
LALIIPALLEIVIFY	SLC36A3	406	Q495N2
AIYQVALLLLVGVVP	STRA6	306	Q9BX79
LLALVYLPGVIAAIV	STEAP1B	106	Q6NZ63
LIGAAVIILLAPVQY	ABCC8	461	Q09428
ALLAFAIPALIIVVV	ADGRF5	1171	Q8IZF2
LVLVASVLLQAVLYP	CD207	51	Q9UJ71
YLLIIRVLLKVEVPE	CYSLTR2	221	Q9NS75
SYPDLLALLIAVIVT	SLC7A14	186	Q8TBB6
LTYVLLDIVIQELFP	SNX14	916	Q9Y5W7
VLILERPLLIETYVG	TPRG1L	236	Q5T0D9
LVKLIPGVEYLVSII	TNC	1766	P24821
YKDVLLVVVPVSLLL	SLAMF8	231	Q9P0V8
AIIVIPLLVDVIYIF	TPTE2	146	Q6XPS3
YVVVPLLGVALLIVI	PRRG3	81	Q9BZD7
FPIIIIQEESLIYLL	TPK1	151	Q9H3S4
ILNILLLLEGAVIVY	TMEM39B	421	Q9GZU3