Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentnuclear envelope lumen

IGF2R SORL1

3.70e-0414432GO:0005641
GeneOntologyCellularComponentaxon

GJC2 PRKCG SETX TNFRSF21 HCFC1 KIF21A HNRNPK WDR47

4.06e-04891438GO:0030424
GeneOntologyCellularComponentanchoring junction

LAMA3 GJC2 PRKCG TRAF4 IGF2R DSC2 HNRNPK JAG1

7.41e-04976438GO:0070161
GeneOntologyCellularComponentsomatodendritic compartment

GJC2 PRKCG GNAS HCFC1 SIPA1L1 KIF21A HNRNPK SORL1 WDR47

7.43e-041228439GO:0036477
GeneOntologyCellularComponentcell-cell junction

LAMA3 GJC2 PRKCG TRAF4 DSC2 JAG1

1.25e-03591436GO:0005911
GeneOntologyCellularComponentdendrite

PRKCG GNAS HCFC1 SIPA1L1 KIF21A HNRNPK WDR47

1.70e-03858437GO:0030425
GeneOntologyCellularComponentdendritic tree

PRKCG GNAS HCFC1 SIPA1L1 KIF21A HNRNPK WDR47

1.72e-03860437GO:0097447
MousePhenoincreased birth weight

IGF2R GNAS

1.62e-053332MP:0009673
MousePhenoincreased birth body size

IGF2R GNAS

3.23e-054332MP:0009702
Domainzf-C3HC4

RNF10 TRAF4 IRF2BP1 RNF113A TRIM7

1.38e-04223425PF00097
Domain-

RNF10 TRAF4 MIB2 PHF24 RNF113A TRIM7

4.70e-044494263.30.40.10
DomainZF_RING_1

RNF10 TRAF4 MIB2 RNF113A TRIM7

4.71e-04291425PS00518
DomainZnf_RING_CS

RNF10 TRAF4 RNF113A TRIM7

4.83e-04163424IPR017907
DomainZF_RING_2

RNF10 TRAF4 MIB2 RNF113A TRIM7

5.24e-04298425PS50089
DomainZnf_RING/FYVE/PHD

RNF10 TRAF4 MIB2 PHF24 RNF113A TRIM7

5.28e-04459426IPR013083
DomainRING

RNF10 TRAF4 MIB2 RNF113A TRIM7

5.83e-04305425SM00184
DomainZnf_C3HC4_RING-type

RNF10 TRAF4 IRF2BP1 TRIM7

5.92e-04172424IPR018957
DomainZnf_RING

RNF10 TRAF4 MIB2 RNF113A TRIM7

7.87e-04326425IPR001841
DomainEGF

LAMA3 NAGPA JAG1 SORL1

1.88e-03235424SM00181
DomainEGF-like_dom

LAMA3 NAGPA JAG1 SORL1

2.32e-03249424IPR000742
DomainKringle-like

CCN5 IGF2R

2.35e-0332422IPR013806
DomainEGF-like_CS

LAMA3 NAGPA JAG1 SORL1

2.75e-03261424IPR013032
DomainEGF_2

LAMA3 NAGPA JAG1 SORL1

2.90e-03265424PS01186
DomainVWC

CCN5 JAG1

3.30e-0338422SM00214
DomainVWF_dom

CCN5 JAG1

4.02e-0342422IPR001007
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TRAF4 MIB2 C2CD3 SLC8B1 IGF2R TNFRSF21 HCFC1 ZNF516 TRIM7

6.81e-06110543935748872
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RNF10 PRKCG C2CD3 SETX GNAS DSC2 ATG13 SIPA1L1

9.19e-0686143836931259
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PACS2 IQSEC3 ATG13 SIPA1L1 PHF24 WDR47

1.05e-0540743612693553
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

PRKCG IQSEC3 IGF2R SIPA1L1 KIF21A HNRNPK ZNF516 WDR47

2.06e-0596343828671696
Pubmed

Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.

MIB2 TANK IRF2BP1 HCFC1 ZNF516

2.57e-0528343521903422
Pubmed

Protease degradomics: mass spectrometry discovery of protease substrates and the CLIP-CHIP, a dedicated DNA microarray of all human proteases and inhibitors.

CCN5 TNFRSF21

4.16e-05843215255181
Pubmed

Transcription is required for establishment of germline methylation marks at imprinted genes.

IGF2R GNAS

6.68e-051043219136628
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

C2CD3 TANK IRF2BP1 SIPA1L1

7.96e-0518443432908313
Pubmed

Gαs regulates asymmetric cell division of cortical progenitors by controlling Numb mediated Notch signaling suppression.

GNAS JAG1

9.78e-051243225916881
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

ADAMTS20 PRKCG GNAS SIPA1L1 KIF21A HNRNPK

1.10e-0462143622794259
Pubmed

Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea.

IGF2R JAG1

1.35e-041443222159122
Pubmed

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform.

LAMA3 GNAS

1.35e-04144329151674
Pubmed

H19 acts as a trans regulator of the imprinted gene network controlling growth in mice.

IGF2R GNAS

1.55e-041543219762426
Pubmed

Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.

PRKCG KIF21A HNRNPK

1.56e-048443319165527
Pubmed

A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains.

TRAF4 TANK

1.77e-041643211279055
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

GJC2 IQSEC3 SIPA1L1 HNRNPK

1.91e-0423143416452087
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

RNF10 MIB2 IRF2BP1

2.25e-049543329643511
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

LAMA3 C2CD3 KCNH8 DSC2 SIPA1L1 HNRNPK

2.67e-0473243634732716
Pubmed

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

SETX ATG13 KIF21A

2.78e-041024339734811
Pubmed

Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.

RNF10 TRAF4 RNF113A

3.02e-0410543322493164
Pubmed

Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.

ATG13 L3MBTL4

3.40e-042243220694011
Pubmed

Identification and characterisation of imprinted genes in the mouse.

IGF2R GNAS

3.72e-042343215163367
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

TTF2 SETX IRF2BP1 HCFC1 HNRNPK RNF113A ZNF516

3.76e-04110343734189442
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

PRKCG IQSEC3 GNAS SIPA1L1

4.02e-0428143428706196
Pubmed

ZFP57 dictates allelic expression switch of target imprinted genes.

IGF2R GNAS

4.40e-042543233500348
Pubmed

Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.

ADAMTS20 IGF2R

4.40e-042543229475039
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

LAMA3 JAG1

4.76e-042643234189436
Pubmed

Rex1/Zfp42 as an epigenetic regulator for genomic imprinting.

GNAS HCFC1

5.14e-042743221233130
Pubmed

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

GNAS JAG1

5.93e-042943221909115
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

TTF2 C2CD3 IGF2R TANK ATG13 SIPA1L1

6.01e-0485343628718761
Pubmed

Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening.

DSC2 JAG1

6.79e-043143232546759
Pubmed

SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes.

MIB2 TANK

6.79e-043143227307491
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

TTF2 SETX GNAS KIF21A HNRNPK

7.35e-0458243520467437
Pubmed

Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase.

RNF10 LAMA3 SIPA1L1

8.23e-0414843322898364
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

PRKCG IQSEC3 SIPA1L1 PHF24

8.84e-0434743417114649
Pubmed

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.

ADAMTS20 SORL1

9.67e-043743224162737
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

LAMA3 IGF2R SORL1

1.11e-0316443332409323
Pubmed

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.

IGF2R DSC2 HNRNPK JAG1

1.18e-0337543432788342
Pubmed

Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins.

LAMA3 TTF2

1.19e-034143219343720
Cytoband12q12

ADAMTS20 KIF21A

9.02e-044743212q12
CytobandEnsembl 112 genes in cytogenetic band chr12q12

ADAMTS20 KIF21A

1.61e-0363432chr12q12
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SETX IGF2R IRF2BP1 JAG1

2.32e-051734344968712af1cca8c932abd3323631d7dcaffd4a66
ToppCellCV-Mild-6|Mild / Virus stimulation, Condition and Cluster

MIB2 IGF2R L3MBTL4 SORL1

2.42e-05175434c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCellwk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MROH7 IQSEC3 ZNF497 WDR47

2.59e-05178434a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF4 TNFRSF21 MPPED1 ZNF516

2.77e-051814344e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF4 TNFRSF21 MPPED1 ZNF516

2.77e-05181434ad30c01290fb98adbd0caed301a584761212c977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF4 TNFRSF21 MPPED1 ZNF516

2.77e-051814343a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCellfacs-Heart-RV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 TNFRSF21 JAG1 SORL1

2.95e-0518443431dbe6119a3bcd266ae5e9b340c853d9ff680dce
ToppCellfacs-Heart-RV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 TNFRSF21 JAG1 SORL1

2.95e-051844349c20b50f8d6ac689d41d5440c835f9db8d04758b
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

TTF2 SLC8B1 TNFRSF21 HCFC1

3.08e-05186434403ac98f72a42721f84fbd7826f251a88ae534a2
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA3 KCNH8 KIF21A SORL1

3.27e-051894345d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA3 KCNH8 KIF21A SORL1

3.48e-05192434d3634574b2e8d2ded6446969361b70761b331aea
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA3 KCNH8 KIF21A SORL1

3.48e-051924341aa5e4d9b32013a3f272561dcb8377f6805706df
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCN5 IGF2R GNAS TNFRSF21

3.55e-051934347386fadc13a437f3b0c99b5d116cd3c5f893529c
ToppCellPCW_07-8.5-Epithelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA3 KCNH8 KIF21A SORL1

3.63e-05194434f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCelldistal-Hematologic-Plasmacytoid_Dendritic-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ZNF469 TRAF4 KCNH8 TNFRSF21

3.77e-05196434170629b9ae82e9a911b93e8739dcd38176fbecb4
ToppCelldistal-1-Hematologic-Plasmacytoid_Dendritic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ZNF469 TRAF4 KCNH8 TNFRSF21

3.85e-05197434166d47359df9279ea8c3946f10bd3d4b88c95857
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA3 TNFRSF21 JAG1 TRIM7

3.93e-05198434fc00cb25cdc6c31b7f9d397bc9f9a8f4e9708003
ToppCellPBMC-Mild-cDC_0|Mild / Compartment, Disease Groups and Clusters

IGF2R DSC2 TRIM7 SORL1

3.93e-05198434fb873b7636bb1c7b119dd5b23d7a20f518e6c6da
ToppCellnormal_Lung-B_lymphocytes-GrB-secreting_B_cells|B_lymphocytes / Location, Cell class and cell subclass

TRAF4 IGF2R GNAS TNFRSF21

4.00e-051994342f6074a2fd3323f258be03042f77929640ad0a75
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ZNF469 TRAF4 KCNH8

8.15e-05874338ca87e4a332ef6f035b13e80dcc0110f32172c9a
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P3|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ZNF469 TRAF4 KCNH8

8.15e-05874334ec3a9489981ed69061c1ca363271edf6a3635d2
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA3 PRKCG TRAF4

1.55e-04108433d620f07243c2628494e689bbfabc14c453f4b1f4
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZNF469 TRAF4 KCNH8

2.86e-0413343363d2f096ae47d9b587acc6c5fbd346e5e58842b8
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZNF469 TRAF4 KCNH8

3.25e-04139433a957ea4e581646c76b16b6a7f89579b8c7ac35b6
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PRKCG IQSEC3 TRIM7

3.76e-041464331bf67a9416f52198931b912a31be4bab09fefd19
ToppCellHealthy_donor-RBC|World / disease group, cell group and cell class (v2)

RNF10 GJC2 KCNH8

4.06e-041504331e1a497ec4b048f7e9cc12dd5dd9aba7fedca9e1
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PRKCG SETX SORL1

4.14e-04151433b698ddc74565d47892c09c3f16d78038da2dd5e7
ToppCellCOVID-19_Mild-PLT_5|World / Disease Group and Platelet Clusters

INTS6L IGF2R SORL1

4.23e-0415243390ba4e8a735ec8921038fa072129535f0e3fd9ae
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PRKCG IQSEC3 TRIM7

4.23e-04152433b8aa62e3cf2b4c252db4bccfa75d881c4fa0a788
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SLC8B1 JAG1 WDR47

4.39e-04154433e65e4636646164610f33f7bbac0d879a3ea55986
ToppCellHealthy_donor-RBC|Healthy_donor / disease group, cell group and cell class (v2)

RNF10 GJC2 KCNH8

4.39e-04154433e080d5104fe6f3f6ef617bbcdccf1332ab7231e1
ToppCellControl-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

INTS6L SETX SORL1

4.47e-041554330a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCellHealthy/Control-RBC|Healthy/Control / Disease group and Cell class

RNF10 GJC2 KCNH8

4.73e-041584331fec4f9affdbfba2e281183b717d4d357d474400
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCN5 ZNF469 KCNH8

4.73e-0415843341cf950983f47a9e55d56041b301006b42853b37
ToppCellSevere-B_naive-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

INTS6L SETX SORL1

4.82e-041594332881b054bbeb479221ee3c38bbd9b0815b123579
ToppCellHealthy/Control-RBC|World / Disease group and Cell class

RNF10 GJC2 KCNH8

4.91e-04160433f10871238e7bdf3e1f65a17070000477196e50fe
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PRKCG PHF24 SORL1

5.00e-04161433ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF4 TNFRSF21 MPPED1

5.37e-041654331703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LAMA3 KCNH8 SORL1

5.56e-0416743325af48c640e67848594f5902867ba325fc105da4
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNH8 KIF21A ZDHHC22

5.56e-0416743317c653b46507c8bb85da95836ae72a6015336142
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGF2R GNAS TNFRSF21

5.56e-04167433b0eb7a40491dd2432f5282f578ce569df86d21a7
ToppCell390C-Myeloid-Dendritic-pDC|390C / Donor, Lineage, Cell class and subclass (all cells)

GJC2 TRAF4 TNFRSF21

5.66e-041684335a2e7a52b7330dce30823695a7b9b26bc47a69ce
ToppCellBasal_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

MROH7 ZNF497 TNFRSF21

5.85e-04170433776d4224a682b6c648041827efd69794f88906f0
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGF2R GNAS TNFRSF21

5.85e-041704331f994b690e881106a5d54b3080ccce6260bc3ac5
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-6|TCGA-Bladder / Sample_Type by Project: Shred V9

DSC2 JAG1 TRIM7

5.95e-041714330e78389f8f3d54570a6deb3dd307b865b46307e9
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

LAMA3 JAG1 L3MBTL4

5.95e-04171433e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCellCOVID-pDC|COVID / Condition, Cell_class and T cell subcluster

TRAF4 KCNH8 TNFRSF21

6.06e-041724333ecbb000495dde32f6153ef6bdea9c8802ff3985
ToppCell3'_v3-GI_small-bowel-Lymphocytic_NK-NK_CD16|GI_small-bowel / Manually curated celltypes from each tissue

IGF2R L3MBTL4 SORL1

6.06e-04172433701de463f85aaad3a4b36a0d5fbc416406620089
ToppCellCOVID-pDC-|COVID / Condition, Cell_class and T cell subcluster

TRAF4 KCNH8 TNFRSF21

6.06e-04172433a7827faa1afab51fdaf0cb1a2babcd2e00d411e5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INTS6L SLC8B1 JAG1

6.16e-041734332acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INTS6L SLC8B1 JAG1

6.16e-041734332415b6ff49f334da570577d4e93484d024a3dbd5
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Lymphocytic-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS20 TTF2 KCNH8

6.26e-041744336987fe7959afce347282f632abc16d800ccab7c4
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CCN5 IQSEC3 DSC2

6.26e-04174433e5f12831187140e84b9a49e93b2376b9fefb1aec
ToppCellBAL-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GJC2 TRAF4 TNFRSF21

6.26e-04174433ab654e87c7eab7f33adc61be7a86da5c4d88008d
ToppCellBAL-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

GJC2 TRAF4 TNFRSF21

6.26e-041744332453419842fd22d066631615403393bfe4449bb8
ToppCellfacs-Heart-LV-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 TNFRSF21 JAG1

6.26e-041744337cd6f9103133f8d7b90f9ff4b3b0b078cf554542
ToppCellBAL-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

GJC2 TRAF4 TNFRSF21

6.26e-04174433d9bccff5258c4277bdd1edbd87e17c327ec125e8
ToppCellfacs-Heart-LV-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 TNFRSF21 JAG1

6.26e-04174433a0a059bb2a64d7011e206db2ebcdf3eb655a925a
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGF2R GNAS TNFRSF21

6.37e-04175433fa16c6ba08dc0cc22e8cf049db0577811d080df6
ToppCellBAL-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GJC2 TRAF4 TNFRSF21

6.37e-041754336d5bdfbe53608e01c3845ecd908ca6d0fecc58f8
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF4 KCNH8 ZDHHC22

6.37e-041754331d1cdbf3221b03e24eae38afd57cbd6736b37a53
ToppCellBAL-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GJC2 TRAF4 TNFRSF21

6.37e-041754336839ee3bb4457d13cb08ca8eb79ae33ddd256783
ToppCellBAL-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GJC2 TRAF4 TNFRSF21

6.37e-041754339d6135e183179968555670abec39dff9da2c3219
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PRKCG PHF24 SORL1

6.37e-0417543321f8f11a8b874d4f7c47931010a2535f2a5a3373
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PRKCG PHF24 SORL1

6.37e-04175433ff0789f5913c9f3c49159e40b1ec3d2ff175ec9f
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF4 KCNH8 ZDHHC22

6.37e-04175433d67c77eee979ad029e7545f383326f0ff77c6e5f
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_Tfh|metastatic_Brain / Location, Cell class and cell subclass

ZNF497 TANK SIPA1L1

6.37e-04175433b732c6a423c28856211002107d8c611dcfb6f265
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CCN5 IQSEC3 DSC2

6.47e-04176433bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCellControl-Myeloid-pDC|Control / Disease group,lineage and cell class (2021.01.30)

GJC2 TRAF4 TNFRSF21

6.47e-04176433baa3563973ea1a351fe028f55828463d2a51bf1a
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF10 CCN5 GJC2

6.47e-04176433fc51e4dcad5456c229d76fdcb9a80c4c79eacf3f
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS20 CCN5 JAG1

6.69e-041784339fc5688cf705a74398d24e10e0aab4758612e72b
ToppCellfacs-SCAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCN5 KIF21A JAG1

6.91e-041804336c70b6b7480507fa94625013222ad338ee7dd1d9
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS20 GJC2 PHF24

7.02e-04181433e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCelldroplet-Marrow-BM|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF10 GNAS IRF2BP1

7.02e-041814334169a1527b9c8f5783b8cc44e3a3924f8ed9a5e2
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-Tuft-related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA3 DSC2 SORL1

7.02e-041814331c04e53f46992a0aea9d3eee985681ec4e71f80d
ToppCelltumor_Lung-Myeloid_cells-pDCs|tumor_Lung / Location, Cell class and cell subclass

TRAF4 IGF2R TNFRSF21

7.02e-04181433c864ffeb9234b8c29754afc91c85a972889617f4
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA3 DSC2 SORL1

7.02e-0418143383adf61f44cebe9e75de175c5dc39237fbf9ed24
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA3 DSC2 SORL1

7.13e-04182433e98ca9df33a1a81fc83ecf73d5141a14f2bc985c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRAF4 KCNH8 SIPA1L1

7.13e-04182433862cc68006918e9e46e22b236302d862737f1061
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTF2 KIF21A ZDHHC22

7.13e-04182433e6968e0bd9cef92052d04ac54e2dd746b37623f6
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF469 SIPA1L1 JAG1

7.25e-041834331645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KCNH8 KIF21A ZDHHC22

7.25e-041834339dfb398b9995d562864fe688861a831ada0814cd
ToppCellfacs-Heart-RA-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 TNFRSF21 JAG1

7.25e-041834332f0dcc65ad4d90ef946919b4462280fdd20c5ea0
ToppCellfacs-Heart-RA-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 TNFRSF21 JAG1

7.25e-041834330f02136359787bd78146617990968baa47a65d86
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

INTS6L LAMA3 KCNH8

7.36e-041844336475a43201b136dcc9b113d2ca4cfa154ed9d65d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS20 PRKCG L3MBTL4

7.36e-0418443323515c28e1f42aab29cef9e5b4a7f45bda7f5520
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

PHF24 MPPED1 JAG1

7.36e-04184433ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TTF2 SLC8B1 SORL1

7.36e-04184433bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRKCG KCNH8 KIF21A

7.48e-04185433ef996f4cdbc3971c6c0460d13df64b075ab22154
ToppCellControl-Lymphoid-ILC_A|Lymphoid / Disease state, Lineage and Cell class

SIPA1L1 JAG1 L3MBTL4

7.48e-04185433520795866d44def5be3910ce8e728045c716a24d
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRKCG KCNH8 KIF21A

7.48e-04185433d51342a3979bd728a80e04126059a3fd8a0dbe3b
ToppCellEndoth-Lymph|World / shred by cell class for parenchyma

GJC2 IQSEC3 PHF24

7.48e-0418543397a6c4cd00684d4085d36ef32f7dbb99563ed357
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KCNH8 KIF21A ZDHHC22

7.48e-04185433512f489daeb3b72d4578dc6f4d0ebb5f38d5bbab
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IQSEC3 GNAS PHF24

7.60e-0418643330dd4164c101006c8d95922d89652b82dbe4b5ea
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IQSEC3 GNAS PHF24

7.60e-04186433eeacf59a9e6bf1c9fd59b6b13d35e8abae228cf0
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS20 GJC2 PHF24

7.60e-0418643320340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMA3 ADAMTS20 PHF24

7.60e-0418643323b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellfacs-Heart-LA-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 TNFRSF21 JAG1

7.72e-04187433a12f383b02b07af32cc53a154685df8dba8fbd3f
ToppCellfacs-Heart-LA-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 TNFRSF21 JAG1

7.72e-04187433c40c152fa14e6afc9188549534b64ccbaded56b3
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS20 IQSEC3 GNAS

7.72e-0418743369b47f00598d647e2a99427ebddf42c339428e47
DiseaseIntellectual Disability

PACS2 PRKCG IQSEC3 GNAS HNRNPK RNF113A

3.35e-05447416C3714756
DiseaseMalignant neoplasm of breast

MROH7 TANK WDR88 SIPA1L1 HNRNPK JAG1 SORL1

6.32e-041074417C0006142
Diseaseosteoarthritis, hand

TTF2 IRF2BP1

1.22e-0337412EFO_1000789

Protein segments in the cluster

PeptideGeneStartEntry
ERLATCTPSDRTHCA

ATG13

326

O75143
CITENDCTHRVDPRI

DSC2

671

Q02487
ECHEASRPSDRQSCV

ADAMTS20

1116

P59510
PHFSDAREVVRSSCI

MROH7

1091

Q68CQ1
TSHPVVRFSCVDCEP

INTS6L

306

Q5JSJ4
VVRVCSNPPCETHET

HCFC1

1071

P51610
RTVRPQCEVCETHSF

LAMA3

1331

Q16787
SRQPCPHVVDCFVSR

GJC2

246

Q5T442
RHPSVFCVLSVAEVC

L3MBTL4

96

Q8NA19
RCVRSVPSLCGVDHT

PRKCG

141

P05129
DVLQRHTLPVVCTCS

PACS2

506

Q86VP3
RFVCVSDTHSRTDPI

MPPED1

91

O15442
FCESCALQHFRTTPR

RNF113A

281

O15541
SRRPENETVLHQFCC

IQSEC3

181

Q9UPP2
DPSHSTCLTEACIRV

EEF1AKMT4-ECE2

206

P0DPD8
EQRRTHPVACSFCPE

C2CD3

1246

Q4AC94
ETFQPHCSIRCRCED

CCN5

111

O76076
PHFTCAVDTENIRRV

GNAS

361

P63092
CRERLEDTHFVQCPS

IRF2BP1

506

Q8IU81
HCRTTPCEVIDSCTV

JAG1

566

P78504
LVLFSPCQHRTVCEE

MIB2

841

Q96AX9
VSDRCDFIRTNPDCH

SLC8B1

61

Q6J4K2
HTPLACEQATECSVR

IGF2R

1641

P11717
FDRPVVVSNCSCTRE

SORL1

666

Q92673
RVCSSCPVGTFTRHE

TNFRSF21

86

O75509
FQECCPHSTDRVVLI

HNRNPK

181

P61978
RQVSTVVCVHEPRCQ

NAGPA

316

Q9UK23
FVIVRVHNPCSDSVC

SIPA1L1

736

O43166
HTRPRSISVEEFCEI

SETX

1141

Q7Z333
TDSELHIPRVCEFCQ

TANK

386

Q92844
AESLFPCRVCTRVFH

PHF24

141

Q9UPV7
NPSTARVHCFEEACV

WDR47

156

O94967
QPRRCCFSEEVTSTE

ZNF516

606

Q92618
QRTHTGERPFECAEC

ZNF497

321

Q6ZNH5
SPSTHFCRVCARVTL

ZDHHC22

91

Q8N966
HPCRFDTNTRVLASC

TRIM7

376

Q9C029
RSITSCCFDPDSQRV

WDR88

231

Q6ZMY6
TIHVCQTRVCPQIDA

KIF21A

231

Q7Z4S6
FVEQVRICSHEVPSC

RNF10

211

Q8N5U6
REPVQVSTCGHRFCD

TRAF4

26

Q9BUZ4
RRTCQATVPHEDTFS

ZNF469

1581

Q96JG9
TCSFVRATDIPVSHC

TTF2

36

Q9UNY4
RFCSLHSTSVCPSRE

KCNH8

906

Q96L42