Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

NET1 MYCBP2 OBSCN ARHGEF17 ARHGEF16 ARHGAP29 HERC2 TBC1D3I TBC1D3G RGL2 TNS3 TBC1D3K TBC1D3F IPO5 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D PLEKHG4 NGB TBC1D3C TBC1D3B KIAA1755 RINL

5.61e-1050722325GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

NET1 MYCBP2 OBSCN ARHGEF17 ARHGEF16 ARHGAP29 HERC2 TBC1D3I TBC1D3G RGL2 TNS3 TBC1D3K TBC1D3F IPO5 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D PLEKHG4 NGB TBC1D3C TBC1D3B KIAA1755 RINL

5.61e-1050722325GO:0030695
GeneOntologyMolecularFunctionenzyme regulator activity

CDKN2A CDKN2D NET1 MYCBP2 NAIP OBSCN ARHGEF17 ARHGEF16 BRPF1 ARHGAP29 PPP1R37 HERC2 TBC1D3I TBC1D3G RGL2 PIF1 TNS3 TBC1D3K TBC1D3F IPO5 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D PLEKHG4 NGB PARP8 TBC1D3C TBC1D3B CCNF GTF2F1 KIAA1755 RINL PIK3R5

7.78e-06141822335GO:0030234
GeneOntologyMolecularFunctionribose phosphate diphosphokinase activity

PRPS2 PRPS1L1 PRPS1

1.35e-0552233GO:0004749
GeneOntologyMolecularFunctionGTPase activator activity

ARHGAP29 TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B RINL

1.63e-0527922313GO:0005096
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate 5-phosphatase activity

SYNJ1 SYNJ2 PIKFYVE

2.68e-0562233GO:0043813
GeneOntologyMolecularFunctiondiphosphotransferase activity

PRPS2 PRPS1L1 PRPS1

2.68e-0562233GO:0016778
GeneOntologyMolecularFunctionmRNA N6-methyladenosine dioxygenase activity

ALKBH5 FTO

1.24e-0422232GO:1990931
GeneOntologyMolecularFunctionglutamate receptor activity

GRID2 GRIN2C GRIN2D GRM2

2.17e-04272234GO:0008066
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

NET1 MYCBP2 OBSCN ARHGEF17 ARHGEF16 HERC2 RGL2 PLEKHG4 KIAA1755 RINL

2.83e-0423122310GO:0005085
GeneOntologyMolecularFunctionphosphatidylinositol phosphate 5-phosphatase activity

SYNJ1 SYNJ2 PIKFYVE

3.62e-04132233GO:0034595
GeneOntologyMolecularFunctionphenanthrene-9,10-epoxide hydrolase activity

AKR7L AKR7A3

3.70e-0432232GO:0019119
GeneOntologyMolecularFunctionphenanthrene-epoxide hydrolase activity

AKR7L AKR7A3

3.70e-0432232GO:0019118
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate phosphatase activity

SYNJ1 SYNJ2 PIKFYVE

6.91e-04162233GO:0106018
GeneOntologyBiologicalProcessactivation of GTPase activity

ARHGEF16 ARHGAP29 TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D PLEKHG4 TBC1D3C TBC1D3B CRK

8.88e-1310922415GO:0090630
GeneOntologyBiologicalProcessregulation of GTPase activity

NET1 RTN4R ARHGEF16 ARHGAP29 RIPOR1 TBC1D3I TBC1D3G PLXNA1 TNS3 TBC1D3K TBC1D3F PLXNA3 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D PLEKHG4 TBC1D3C TBC1D3B CRK

1.21e-1033522421GO:0043087
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

NET1 RTN4R ARHGEF16 ARHGAP29 TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D PLEKHG4 TBC1D3C TBC1D3B CRK

1.54e-0924422417GO:0043547
GeneOntologyBiologicalProcesspositive regulation of hydrolase activity

CDKN2A NET1 RTN4R BCL2 ARHGEF16 FCRL3 ARHGAP29 TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D PLEKHG4 TBC1D3C TBC1D3B CRK

5.87e-0749922420GO:0051345
GeneOntologyBiologicalProcessregulation of hydrolase activity

CDKN2A CDKN2D NET1 RTN4R NAIP BCL2 ARHGEF16 FCRL3 ARHGAP29 RIPOR1 TBC1D3I TBC1D3G PLXNA1 TNS3 TBC1D3K TBC1D3F PLXNA3 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D PLEKHG4 TBC1D3C TBC1D3B CRK

3.63e-0687822426GO:0051336
GeneOntologyBiologicalProcessnucleoside monophosphate biosynthetic process

PRPS2 PRPS1L1 ADSL DHODH DUT PRPS1

1.45e-05492246GO:0009124
GeneOntologyBiologicalProcess5-phosphoribose 1-diphosphate metabolic process

PRPS2 PRPS1L1 PRPS1

2.47e-0562243GO:0046391
GeneOntologyBiologicalProcess5-phosphoribose 1-diphosphate biosynthetic process

PRPS2 PRPS1L1 PRPS1

2.47e-0562243GO:0006015
GeneOntologyBiologicalProcessribonucleoside monophosphate biosynthetic process

PRPS2 PRPS1L1 ADSL DHODH PRPS1

5.41e-05382245GO:0009156
GeneOntologyBiologicalProcessolfactory nerve formation

PLXNA1 PLXNA3

1.17e-0422242GO:0021628
GeneOntologyCellularComponentribose phosphate diphosphokinase complex

PRPS2 PRPS1L1 PRPS1

1.21e-0552253GO:0002189
DomainTBC

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

2.75e-104922410SM00164
DomainRabGAP-TBC

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

6.26e-105322410PF00566
DomainRab-GTPase-TBC_dom

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

9.19e-105522410IPR000195
DomainTBC_RABGAP

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

9.19e-105522410PS50086
DomainPRPP_SYNTHASE

PRPS2 PRPS1L1 PRPS1

1.70e-0632243PS00114
DomainPRib_PP_synth_CS

PRPS2 PRPS1L1 PRPS1

1.70e-0632243IPR000842
DomainPribosyltran_N

PRPS2 PRPS1L1 PRPS1

1.67e-0552243PF13793
DomainPribosyl_synth

PRPS2 PRPS1L1 PRPS1

1.67e-0552243PF14572
DomainRib-P_diPkinase

PRPS2 PRPS1L1 PRPS1

1.67e-0552243IPR005946
DomainPribosyltran_N

PRPS2 PRPS1L1 PRPS1

1.67e-0552243IPR029099
DomainIg-like_fold

MYCBP2 OBSCN LINGO3 FCRL3 PTPRB HMCN2 NFATC2 PXDNL MYPN VSIG10L SPACA6 UNC5D PLXNA1 PLXNA3 SDK2 VWA1 PTPRU NFAM1 EBI3 LRRN4 IGSF21 ANKFN1

4.34e-0570622422IPR013783
DomainDUF1866

SYNJ1 SYNJ2

1.43e-0422242IPR015047
DomainDUF1866

SYNJ1 SYNJ2

1.43e-0422242PF08952
DomainDUF1866

SYNJ1 SYNJ2

1.43e-0422242SM01165
Domain-

MYCBP2 OBSCN LINGO3 FCRL3 PTPRB NFATC2 PXDNL MYPN VSIG10L SPACA6 UNC5D PLXNA1 PLXNA3 SDK2 VWA1 PTPRU EBI3 LRRN4 IGSF21 ANKFN1

1.51e-04663224202.60.40.10
DomainARM-type_fold

URB1 RRP12 ANKAR PKP2 RIPOR1 UNC79 IPO5 RNPEPL1 USP24 WDFY4 EIF4G1 PRKDC LRBA

2.40e-0433922413IPR016024
DomainPribosyltran

PRPS2 PRPS1L1 PRPS1

2.62e-04112243PF00156
DomainPRTase-like

PRPS2 PRPS1L1 PRPS1

3.46e-04122243IPR029057
DomainPRibTrfase_dom

PRPS2 PRPS1L1 PRPS1

3.46e-04122243IPR000836
Domain-

PRPS2 PRPS1L1 PRPS1

3.46e-041222433.40.50.2020
DomainCAC1F_C

CACNA1D CACNA1F

4.26e-0432242IPR031688
DomainUCP038083_PDZ

GIPC2 GIPC3

4.26e-0432242IPR017379
DomainCAC1F_C

CACNA1D CACNA1F

4.26e-0432242PF16885
DomainEGF_CA

SVEP1 STAB1 HMCN2 VWA2 NOTCH4 FAT4 MEGF8

6.78e-041222247SM00179
DomainEGF-like_Ca-bd_dom

SVEP1 STAB1 HMCN2 VWA2 NOTCH4 FAT4 MEGF8

7.47e-041242247IPR001881
Domainfn3

OBSCN PTPRB SDK2 VWA1 PTPRU EBI3 LRRN4 ANKFN1

7.68e-041622248PF00041
DomainVDCC_L_a1su

CACNA1D CACNA1F

8.46e-0442242IPR005446
DomainDH_1

NET1 OBSCN ARHGEF17 ARHGEF16 PLEKHG4

9.48e-04632245PS00741
DomainANF_lig-bd_rcpt

GRID2 GRIN2C GRIN2D GRM2

9.75e-04372244IPR001828
DomainANF_receptor

GRID2 GRIN2C GRIN2D GRM2

9.75e-04372244PF01094
DomainPeripla_BP_I

GRID2 GRIN2C GRIN2D GRM2

1.19e-03392244IPR028082
DomainGDS_CDC24_CS

NET1 OBSCN ARHGEF16 PLEKHG4

1.19e-03392244IPR001331
DomainLig_chan-Glu_bd

GRID2 GRIN2C GRIN2D

1.22e-03182243PF10613
DomainGlu/Gly-bd

GRID2 GRIN2C GRIN2D

1.22e-03182243IPR019594
DomainLig_chan-Glu_bd

GRID2 GRIN2C GRIN2D

1.22e-03182243SM00918
DomainIontro_rcpt

GRID2 GRIN2C GRIN2D

1.22e-03182243IPR001320
DomainIono_rcpt_met

GRID2 GRIN2C GRIN2D

1.22e-03182243IPR001508
DomainLig_chan

GRID2 GRIN2C GRIN2D

1.22e-03182243PF00060
DomainPBPe

GRID2 GRIN2C GRIN2D

1.22e-03182243SM00079
DomainRhoGEF

NET1 OBSCN ARHGEF17 ARHGEF16 PLEKHG4

1.34e-03682245SM00325
DomainNUT

NUTM2A NUTM2B

1.40e-0352242IPR024310
DomainNUT_N

NUTM2A NUTM2B

1.40e-0352242IPR024309
DomainPHR

MYCBP2 BTBD2

1.40e-0352242IPR012983
DomainNUT

NUTM2A NUTM2B

1.40e-0352242PF12881
DomainSyja_N

SYNJ1 SYNJ2

1.40e-0352242PF02383
DomainPHR

MYCBP2 BTBD2

1.40e-0352242PF08005
DomainSAC

SYNJ1 SYNJ2

1.40e-0352242PS50275
DomainSAC_dom

SYNJ1 SYNJ2

1.40e-0352242IPR002013
DomainRhoGEF

NET1 OBSCN ARHGEF17 ARHGEF16 PLEKHG4

1.52e-03702245PF00621
DomainDH_2

NET1 OBSCN ARHGEF17 ARHGEF16 PLEKHG4

1.52e-03702245PS50010
Domain-

NET1 OBSCN ARHGEF17 ARHGEF16 PLEKHG4

1.62e-037122451.20.900.10
DomainDH-domain

NET1 OBSCN ARHGEF17 ARHGEF16 PLEKHG4

1.62e-03712245IPR000219
DomainFN3

OBSCN PTPRB SDK2 VWA1 PTPRU EBI3 LRRN4 ANKFN1

1.80e-031852248SM00060
PathwayWP_17Q12_COPY_NUMBER_VARIATION_SYNDROME

GPR179 TBC1D3I TBC1D3G TBC1D3K TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3C TBC1D3B

3.26e-079917110M46448
Pubmed

TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.

TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

8.73e-25112311116863688
Pubmed

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

GPR179 KSR1 TBC1D3G TBC1D3F TBC1D3E SDK2 TBC1D3 TBC1D3H TBC1D3D BTBD17 TBC1D3B

2.53e-12742311116625196
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

LZTR1 MAN2A2 MYCBP2 OBSCN ABCA7 ST14 RYR1 URB1 SYNJ1 RRP12 NAV1 RIPOR1 HERC2 RGL2 PLXNA1 PLXNA3 ITPRIPL2 RNPEPL1 MEX3D TRMT1 GRIN2D PIKFYVE MEGF8 EIF4G1 SLC7A5 PRKDC LRBA CEP170B

1.56e-0911052312835748872
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CDKN2A NET1 MYCBP2 EXPH5 ARHGEF17 ARHGEF16 HAUS8 KSR1 SYNJ1 SYNJ2 CLK3 NAV1 PKP2 PPIP5K2 RGL2 TNS3 WDR62 TCF20 PARP8 MEGF8 EIF4G1 CEP152 SH3RF3 CEP170B

4.06e-098612312436931259
Pubmed

Promoter regions of the human X-linked housekeeping genes PRPS1 and PRPS2 encoding phosphoribosylpyrophosphate synthetase subunit I and II isoforms.

PRPS2 PRPS1L1 PRPS1

2.89e-07323131314091
Pubmed

PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.

TBC1D3F TBC1D3 TBC1D3D

1.15e-064231312359748
Pubmed

Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.

TBC1D3F TBC1D3 TBC1D3D

1.15e-06423138406013
Pubmed

The Tre2 (USP6) oncogene is a hominoid-specific gene.

TBC1D3 TBC1D3D TBC1D3C

2.86e-065231312604796
Pubmed

Roles of the glutamate receptor epsilon2 and delta2 subunits in the potentiation and prepulse inhibition of the acoustic startle reflex.

GRID2 GRIN2C GRIN2D

2.86e-065231311488959
Pubmed

Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.

TBC1D3F TBC1D3 TBC1D3D

2.86e-06523138471161
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ARHGEF17 USP19 CRACD RRP12 NAV3 NAV1 RIPOR1 KATNIP ARRDC3 TCF20 MEGF8 TLE4 CEP170B

3.89e-064072311312693553
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

PDE7A KREMEN1 MYCBP2 OBSCN RUSC1 DMXL1 FREM2 ST6GAL2 R3HCC1L RECQL4 RIPOR1 NEURL1B HERC2 UNC5D PLXNA3 ITPRIPL2 PGGHG USP24 PTPRU AKR7L CEP152 ADAMTS14 CEP170B

7.26e-0612152312315146197
Pubmed

Proteome-wide analysis of phospho-regulated PDZ domain interactions.

NET1 FASTKD5 ARHGEF16 GRIN2C GUCY1A2

8.62e-0642231530126976
Pubmed

The Maternal Microbiome Programs the m6A Epitranscriptome of the Mouse Fetal Brain and Intestine.

ALKBH5 AXIN2 FTO PLXNA3

2.15e-0525231435874829
Pubmed

DNA segments mapped by reciprocal use of microsatellite primers between mouse and rat.

INHA BCL2 SCN2A TG

2.15e-052523148268655
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

MYCBP2 RUSC1 SYNJ1 NAV1 WDR62 TCF20 USP24 TPGS1 CRK TLE4 ZFHX3 LRBA

2.64e-054182311234709266
Pubmed

Implication of genetic variants near SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, FTO, TCF2, KCNQ1, and WFS1 in type 2 diabetes in a Chinese population.

CDKN2A FTO TCF20

3.35e-0510231320509872
Pubmed

Altered p16 and Bcl-2 expression reflects pathologic development in hydatidiform moles and choriocarcinoma.

CDKN2A BCL2

4.39e-052231223065465
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

4.39e-052231219694741
Pubmed

The Synaptojanins in the murine small and large intestine.

SYNJ1 SYNJ2

4.39e-052231227878645
Pubmed

Voltage-Gated Cav1 Channels in Disorders of Vision and Hearing.

CACNA1D CACNA1F

4.39e-052231225966695
Pubmed

Rare loss of function mutations in N-methyl-D-aspartate glutamate receptors and their contributions to schizophrenia susceptibility.

GRIN2C GRIN2D

4.39e-052231229317596
Pubmed

NMDA GluN2C/2D receptors contribute to synaptic regulation and plasticity in the anterior cingulate cortex of adult mice.

GRIN2C GRIN2D

4.39e-052231233766086
Pubmed

Cell Differentiation and Aging Lead To Up-Regulation of FTO, While the ALKBH5 Protein Level Was Stable During Aging but Up-Regulated During in vitro-Induced Cardiomyogenesis.

ALKBH5 FTO

4.39e-052231237795886
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

4.39e-052231230693367
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

4.39e-052231229649454
Pubmed

[Increased activity of PRPP synthetase].

PRPS2 PRPS1

4.39e-052231218409517
Pubmed

Homozygous deletion of INK4a/ARF genes and overexpression of bcl-2 in relation with poor prognosis in immunocompetent patients with primary central nervous system lymphoma of the diffuse large B-cell type.

CDKN2A BCL2

4.39e-052231211804283
Pubmed

Enhanced function of NR2C/2D-containing NMDA receptor in the nucleus accumbens contributes to peripheral nerve injury-induced neuropathic pain and depression in mice.

GRIN2C GRIN2D

4.39e-052231235057644
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

4.39e-052231233096315
Pubmed

PRPS1-mediated purine biosynthesis is critical for pluripotent stem cell survival and stemness.

PRPS2 PRPS1

4.39e-052231233493137
Pubmed

NMDA receptors containing GluN2C and GluN2D subunits have opposing roles in modulating neuronal oscillations; potential mechanism for bidirectional feedback.

GRIN2C GRIN2D

4.39e-052231231786200
Pubmed

Developmentally regulated alternative splicing in a novel synaptojanin.

SYNJ1 SYNJ2

4.39e-05223129442075
Pubmed

Tissue-differential expression of two distinct genes for phosphoribosyl pyrophosphate synthetase and existence of the testis-specific transcript.

PRPS2 PRPS1

4.39e-05223122537655
Pubmed

m6A demethylase ALKBH5 controls CD4+ T cell pathogenicity and promotes autoimmunity.

ALKBH5 FTO

4.39e-052231234134995
Pubmed

Purkinje cell-specific and inducible gene recombination system generated from C57BL/6 mouse ES cells.

GRID2 GRIN2C

4.39e-052231211243853
Pubmed

Sarcomas induced in discrete subsets of prospectively isolated skeletal muscle cells.

CDKN2A PRKDC

4.39e-052231222135462
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

4.39e-052231210827969
Pubmed

Mitochondrial Regulation of the Hippocampal Firing Rate Set Point and Seizure Susceptibility.

SCN1A DHODH

4.39e-052231231047779
Pubmed

BCL-2 expression by leukaemic blasts in a SCID mouse model of biphenotypic leukaemia associated with the t(4;11)(q21;q23) translocation.

BCL2 PRKDC

4.39e-05223127669664
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

4.39e-05223121317301
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

4.39e-052231231439038
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

4.39e-052231215249644
Pubmed

C-terminal modulator controls Ca2+-dependent gating of Ca(v)1.4 L-type Ca2+ channels.

CACNA1D CACNA1F

4.39e-052231216921373
Pubmed

In the Telencephalon, GluN2C NMDA Receptor Subunit mRNA is Predominately Expressed in Glial Cells and GluN2D mRNA in Interneurons.

GRIN2C GRIN2D

4.39e-052231229651654
Pubmed

Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes.

GRIN2C GRIN2D

4.39e-052231231110197
Pubmed

Novel Prognostic Implications of Methylated RNA and Demethylases in Resected HCC and Background Liver Tissue.

ALKBH5 FTO

4.39e-052231233288560
Pubmed

N(6)-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5.

ALKBH5 FTO

4.39e-052231227156733
Pubmed

Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.

SCN1A SCN2A

4.39e-052231226311622
Pubmed

Bcl-2 expression promotes B- but not T-lymphoid development in scid mice.

BCL2 PRKDC

4.39e-05223128133891
Pubmed

Antisense oligonucleotides suppress B-cell lymphoma growth in a SCID-hu mouse model.

BCL2 PRKDC

4.39e-05223128084613
Pubmed

The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.

SCN1A SCN2A

4.39e-052231221377452
Pubmed

CD3+ T cells in severe combined immunodeficiency (scid) mice. VI. Rescue of scid-derived, IgM-producing B cells by transfer of CD4+ CD8- T cells from various lymphoid organs.

GRID2 PRKDC

4.39e-05223121358814
Pubmed

HIV-1 Tat-mediated apoptosis in human blood-retinal barrier-associated cells.

BCL2 GRIN2C GRIN2D

4.59e-0511231324739951
Pubmed

Semaphorin-5B Controls Spiral Ganglion Neuron Branch Refinement during Development.

GFI1 PLXNA1 PLXNA3

4.59e-0511231331209173
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

CDKN2A NET1 ARHGEF17 ARHGEF16 DDX50 COX5A BRPF1 ARHGAP29 PKP2 PPIP5K2 IPO5 PLEKHG4 NOA1 DUT GRSF1 CRK TNKS2 PSPC1

4.62e-059162311832203420
Pubmed

An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program.

UNC5D TLE4 EIF4G1

6.09e-0512231325456498
Pubmed

The mouse Rhl1 and Rhag genes: sequence, organization, expression, and chromosomal mapping.

PTPRU AKR7L AKR7A3

6.09e-0512231310495887
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MYCBP2 USP19 PASK BRPF1 RRP12 RIPOR1 UNC5D WDR62 TCF20 USP24 SMTN EEF2 TLE4 EIF4G1 SLC7A5 PRKDC

6.84e-057742311615302935
Pubmed

The protein interaction landscape of the human CMGC kinase group.

CDKN2A CDKN2D SELENOS FASTKD5 AXIN2 PASK DDX50 CLK3 NAV1 PKP2 HERC2 WDR62 KPTN EEF2 TLE4

7.18e-056952311523602568
Pubmed

Common type 2 diabetes risk gene variants associate with gestational diabetes.

CDKN2A FTO TCF20

7.87e-0513231318984664
Pubmed

Clinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort.

SCN1A SCN2A

1.31e-043231232005694
Pubmed

Genetic variants in DNA repair genes and the risk of cutaneous malignant melanoma in melanoma-prone families with/without CDKN2A mutations.

CDKN2A PRKDC

1.31e-043231221671477
Pubmed

Usp16 modulates Wnt signaling in primary tissues through Cdkn2a regulation.

CDKN2A AXIN2

1.31e-043231230504774
Pubmed

Aldo-keto reductase 7A5 (AKR7A5) attenuates oxidative stress and reactive aldehyde toxicity in V79-4 cells.

AKR7L AKR7A3

1.31e-043231224590062
Pubmed

Cell-cycle-associated markers and clinical outcome in human epithelial cancers: a tissue microarray study.

CDKN2A BCL2

1.31e-043231216273250
Pubmed

Genetic dissection of horizontal cell inhibitory signaling in mice in complete darkness in vivo.

CACNA1D CACNA1F

1.31e-043231226024096
Pubmed

Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens.

GRIN2C GRIN2D

1.31e-043231235867797
Pubmed

Evidence of a role for the INK4 family of cyclin-dependent kinase inhibitors in ovarian granulosa cell tumors.

CDKN2A CDKN2D

1.31e-043231212203782
Pubmed

The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor.

NUTM2A NUTM2B

1.31e-043231222456610
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A

1.31e-043231212610651
Pubmed

Locus-specific DNA methylation in the placenta is associated with levels of pro-inflammatory proteins in cord blood and they are both independently affected by maternal smoking during pregnancy.

GFI1 AHRR

1.31e-043231228820654
Pubmed

Epigenetic silencing of Bcl-2, CEBPA and p14(ARF) by the AML1-ETO oncoprotein contributing to growth arrest and differentiation block in the U937 cell line.

CDKN2A BCL2

1.31e-043231223673926
Pubmed

Novel homodimeric and heterodimeric rat gamma-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteins.

AKR7L AKR7A3

1.31e-043231212071861
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A

1.31e-043231218784617
Pubmed

Differential expression of plexin-A subfamily members in the mouse nervous system.

PLXNA1 PLXNA3

1.31e-043231211241833
Pubmed

Gene Polymorphism Association with Type 2 Diabetes and Related Gene-Gene and Gene-Environment Interactions in a Uyghur Population.

CDKN2A FTO

1.31e-043231226873362
Pubmed

Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53.

NAV3 NAV1

1.31e-043231215158073
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN2A

1.31e-043231228518218
Pubmed

Involvement of cytochrome c oxidase subunits Va and Vb in the regulation of cancer cell metabolism by Bcl-2.

BCL2 COX5A

1.31e-043231219834492
Pubmed

RUVBL2 is a novel repressor of ARF transcription.

CDKN2A CDKN2D

1.31e-043231222285491
Pubmed

Fat mass and obesity-associated protein (FTO) mediated m6A modification of circFAM192A promoted gastric cancer proliferation by suppressing SLC7A5 decay.

FTO SLC7A5

1.31e-043231238556586
Pubmed

The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice.

CDKN2A PRKDC

1.31e-043231221209895
Pubmed

Arginylation regulates purine nucleotide biosynthesis by enhancing the activity of phosphoribosyl pyrophosphate synthase.

PRPS2 PRPS1

1.31e-043231226175007
Pubmed

Auditory pathway and auditory brainstem response in mice lacking NMDA receptor epsilon 1 and epsilon 4 subunits.

GRIN2C GRIN2D

1.31e-04323129718984
Pubmed

Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.

SCN1A SCN2A

1.31e-043231232185219
Pubmed

[Purification of recombinant AKR7A5 protein and measurement of substrate specificity of AKR7A5 towards naphthoquinone and its derivatives].

AKR7L AKR7A3

1.31e-043231222863590
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A

1.31e-043231223859570
Pubmed

Partial reconstitution of mammalian phosphoribosylpyrophosphate synthetase in Escherichia coli cells. Coexpression of catalytic subunits with the 39-kDa associated protein leads to formation of soluble multimeric complexes of various compositions.

PRPS2 PRPS1

1.31e-04323129366267
Pubmed

Dysregulated ΔNp63α inhibits expression of Ink4a/arf, blocks senescence, and promotes malignant conversion of keratinocytes.

CDKN2A CDKN2D

1.31e-043231221789189
Pubmed

Diversity of human copy number variation and multicopy genes.

TBC1D3G TBC1D3E

1.31e-043231221030649
Pubmed

Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.

CDKN2A CDKN2D

1.31e-04323129751050
Pubmed

Characterisation of a novel mouse liver aldo-keto reductase AKR7A5.

AKR7L AKR7A3

1.31e-043231212123834
Pubmed

Dysregulated gene expressions of MEX3D, FOS and BCL2 in human induced-neuronal (iN) cells from NF1 patients: a pilot study.

BCL2 MEX3D

1.31e-043231229066822
Pubmed

p53 and p16Ink4a/p19Arf Loss Promotes Different Pancreatic Tumor Types from PyMT-Expressing Progenitor Cells.

CDKN2A CDKN2D

1.31e-043231227664376
Pubmed

Molecular mechanism of c-Myc and PRPS1/2 against thiopurine resistance in Burkitt's lymphoma.

PRPS2 PRPS1

1.31e-043231232391636
Pubmed

Correlation of nuclear morphometry of primary melanoma of the skin with clinicopathological parameters and expression of tumor suppressor proteins (p53 and p16(INK4a)) and bcl-2 oncoprotein.

CDKN2A BCL2

1.31e-043231223818364
Pubmed

Cloning of cDNAs for human phosphoribosylpyrophosphate synthetases 1 and 2 and X chromosome localization of PRPS1 and PRPS2 genes.

PRPS2 PRPS1

1.31e-04323121962753
Pubmed

Nav1.2 is expressed in caudal ganglionic eminence-derived disinhibitory interneurons: Mutually exclusive distributions of Nav1.1 and Nav1.2.

SCN1A SCN2A

1.31e-043231228784306
Pubmed

Identification of plexin family molecules in mice.

PLXNA1 PLXNA3

1.31e-04323128806646
InteractionFIBIN interactions

MAN2A2 CHST12 PLXNA1 TRHDE PLXNA3 PTPRU MEGF8 CHRD

1.20e-06712248int:FIBIN
InteractionYWHAH interactions

CDKN2A NET1 MYCBP2 EXPH5 ARHGEF17 ARHGEF16 HAUS8 KSR1 SYNJ1 SYNJ2 CLK3 RECQL4 NAV1 PKP2 PPIP5K2 RGL2 TNS3 WDR62 TCF20 PARP8 MEX3D CNTRL CRK CCNF MEGF8 EIF4G1 CEP152 LRBA SH3RF3 CEP170B

5.29e-06110222430int:YWHAH
InteractionYWHAB interactions

CDKN2A PDE7A MYCBP2 EXPH5 ARHGEF17 ARHGEF16 KSR1 NFATC2 SYNJ2 CLK3 RECQL4 FER NAV1 PKP2 PPIP5K2 RGL2 VWA2 SAP130 TNS3 WDR62 IPO5 NGB PARP8 CRK CCNF EIF4G1 SH3RF3 CEP170B

8.64e-06101422428int:YWHAB
InteractionPRG2 interactions

THSD4 MAN2A2 HS6ST2 ST14 PASK CHST12 PLXNA1 PLEKHG4 VWA1 PTPRU CHRD ADAMTS14 SPEM1

1.95e-0528522413int:PRG2
InteractionYWHAG interactions

CDKN2A NET1 MYCBP2 EXPH5 ARHGEF17 ARHGEF16 CRACD HAUS8 KSR1 SYNJ1 NFATC2 SYNJ2 CLK3 RECQL4 ARHGAP29 NAV1 PKP2 PPIP5K2 RGL2 TNS3 WDR62 NGB PARP8 USP24 CRK CCNF EIF4G1 PRKDC LRBA SH3RF3 CEP170B

2.23e-05124822431int:YWHAG
InteractionMFAP4 interactions

THSD4 MAN2A2 HS6ST2 CHST12 PLXNA1 PLXNA3 PTPRU TLE4 CHRD

2.59e-051392249int:MFAP4
InteractionTOP3B interactions

LZTR1 MAN2A2 MYCBP2 OBSCN ABCA7 ST14 RYR1 AXIN2 URB1 SYNJ1 RRP12 NAV1 PKP2 RIPOR1 HERC2 RGL2 PLXNA1 MOV10 IPO5 PLXNA3 ITPRIPL2 RNPEPL1 MEX3D TRMT1 GRIN2D GRSF1 PIKFYVE CCNF MEGF8 EIF4G1 SLC7A5 PRKDC LRBA CEP170B

3.70e-05147022434int:TOP3B
InteractionGOLGA1 interactions

LZTR1 DMXL1 PASK R3HCC1L ARHGAP29 PPP1R37 NAV1 USP24 CEP152 CEP170B

3.99e-0518322410int:GOLGA1
InteractionHLA-G interactions

MAN2A2 HS6ST2 ST14 CHST12 PLXNA1 PLXNA3 PTPRU MEGF8

5.27e-051182248int:HLA-G
InteractionDNASE1L1 interactions

THSD4 MAN2A2 ST14 PLXNA1 PLXNA3 MEGF8 CHRD ADAMTS14

5.94e-051202248int:DNASE1L1
InteractionBTNL2 interactions

THSD4 MAN2A2 HS6ST2 ST14 CHST12 PLXNA1 PLXNA3 PTPRU MEGF8

6.09e-051552249int:BTNL2
InteractionWDR83 interactions

NET1 FRS3 ARHGEF17 TBC1D3F TBC1D3 CNTRL TBC1D3B CRK PIKFYVE CEP152

7.12e-0519622410int:WDR83
InteractionGIPC3 interactions

ST6GAL2 MOV10 GIPC3

7.28e-0582243int:GIPC3
InteractionSLC16A1 interactions

RECQL4 COQ9 ARRDC3 HERC2 PLEKHG4 CNTRL GRM2 CCNF EEF2 SLC7A5

8.42e-0520022410int:SLC16A1
CytobandEnsembl 112 genes in cytogenetic band chr17q12

GPR179 TBC1D3I TBC1D3G TBC1D3K TBC1D3F TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

1.71e-1114923112chr17q12
Cytoband19p13.3

LINGO3 ABCA7 MEX3D TPGS1 BTBD2 GIPC3 EEF2 GTF2F1 EBI3

3.65e-06237231919p13.3
Cytoband12q15-q21

PTPRB TRHDE

7.54e-053231212q15-q21
Cytoband17q12

TBC1D3F TBC1D3 TBC1D3H TBC1D3C TBC1D3B

1.50e-0499231517q12
CytobandEnsembl 112 genes in cytogenetic band chr19p13

CDKN2D ZNF627 LINGO3 ABCA7 HAUS8 MEX3D TRMT1 TPGS1 BTBD2 GIPC3 EEF2 GTF2F1 EBI3

2.26e-0479723113chr19p13
GeneFamilyFibronectin type III domain containing

OBSCN PTPRB SDK2 VWA1 PTPRU EBI3 LRRN4 ANKFN1

3.51e-051601408555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

OBSCN LINGO3 HMCN2 PXDNL MYPN UNC5D SDK2 SIGLEC16

3.67e-051611408593
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

NET1 OBSCN ARHGEF17 ARHGEF16 PLEKHG4

1.58e-04661405722
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN2C GRIN2D

1.22e-03714021201
GeneFamilyAlkylation repair homologs

ALKBH5 FTO

2.07e-0391402401
GeneFamilyWD repeat domain containing|BEACH domain containing

WDFY4 LRBA

2.07e-03914021230
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN2A

2.07e-03914021203
GeneFamilyPlexins

PLXNA1 PLXNA3

2.07e-0391402683
CoexpressionGSE32255_WT_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_UP

PDE7A KREMEN1 ARHGAP29 UNC79 SDK2 SYNM NFAM1 PDLIM4 ADAMTS14 PIK3R5

1.16e-0615522910M8913
CoexpressionSOGA_COLORECTAL_CANCER_MYC_UP

PRPS2 PRPS1L1 ADSL DHODH DUT ASNS SLC7A5

7.73e-06822297M45007
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

CDKN2A GIPC2 ARHGEF17 ST14 SVEP1 FREM2 PTPRB NFATC2 ARHGAP29 PKP2 PIF1 TNS3 TRHDE FAT4 ITPRIPL2 GRIN2C PTPRU LFNG GIPC3 LPL NR2E1 CHRD IGSF21 PIK3R5 B3GAT2

8.79e-06107422925M1941
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

CDKN2D ABCA3 PDE7A MYCBP2 HS6ST2 NUTM2A FRS3 RUSC1 ST6GAL2 SYNJ1 SCN1A SCN2A ANKAR NAV3 NAV1 UNC79 PLXNA1 TRHDE PLXNA3 TBC1D3 GRID2 IKZF4 ASNS ZFHX3 CDH4

1.44e-05110622925M39071
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05

PAOX FREM2 TBC1D3G TBC1D3K TBC1D3F TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B

2.69e-099022311PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlasEctoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

SPATA7 ABCA3 MAN2A2 HS6ST2 ARHGEF17 ABCA7 FREM2 CLK3 NAV1 RIPOR1 TBC1D3G UNC5D TNS3 MOV10 TBC1D3K TBC1D3F DXO SDK2 TBC1D3 TBC1D3H TBC1D3L PCDHGC4 TBC1D3D TBC1D3C TBC1D3B LFNG PDLIM4 TLE4 IGSF21

3.10e-06107522329PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlasDE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05

TBC1D3G TBC1D3K TBC1D3F TBC1D3 TBC1D3H TBC1D3L PGGHG TBC1D3D SYNM TBC1D3C TBC1D3B PIK3R5

1.03e-0524222312PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RYR1 STAB1 NFATC2 RECQL4 PIF1 WDR62 CNTRL WDFY4 CCNF IGSF21 PIK3R5

4.23e-091872311173931a5ea73799095daff100b5f18853c57c74dc
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN FREM2 SCN2A NAV3 UNC79 UNC5D TRHDE CACNA1F FAT4

5.32e-0718423192cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN FREM2 SCN2A NAV3 UNC79 UNC5D TRHDE CACNA1F FAT4

5.32e-0718423192b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN FREM2 SCN2A NAV3 UNC79 UNC5D TRHDE CACNA1F FAT4

5.32e-071842319ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PDE7A EXPH5 HS6ST2 FREM2 UNC79 TCF20 PARP8 IKZF4 TLE4

6.37e-071882319b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDE7A BCL2 GFI1 NFATC2 NLRC3 PARP8 TG SLC7A5 PIK3R5

1.07e-0620023198474e5d031d25bfb8461d39fa2053da01a6304fc
ToppCell(09)_Ionocytes-(3)_72hpi|(09)_Ionocytes / shred by cell type and Timepoint

PDE7A BCL2 VWA2 USP24 FADS1 TLE4 PSPC1

1.74e-061102317fce7d5a0617fc664b657f5bb9abb290e7cc234cb
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPATA7 STAB1 SCN1A PIF1 WDR62 IKZF4 CEP152 PRPS1

2.35e-0616423184307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPATA7 STAB1 SCN1A PIF1 WDR62 IKZF4 CEP152 PRPS1

2.35e-0616423181d84aa5b925f502ee9c5fa39714490f613a58028
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN2D PDE7A BCL2 GFI1 NLRC3 TG ADAMTS14 RINL

2.81e-0616823181254c66f0cd53ef3b913933c0b0648d091da07e9
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ST6GAL2 RASSF3 NEURL1B UNC5D TRHDE NGB GUCY1A2 PLCH2

3.07e-0617023183174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

SLC15A3 ABCA7 SLC26A1 STAB1 NAV1 KATNIP GRIN2D MEGF8

3.34e-061722318f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NET1 SLC15A3 CRACD RASSF3 ITPRIPL2 WDFY4 LPL PNPLA7

3.96e-061762318e74ad0db3b05897edcfabeb11008ede2b9eeb638
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NET1 SLC15A3 CRACD RASSF3 ITPRIPL2 WDFY4 LPL PNPLA7

4.13e-06177231871919b5c9bfa87fdd2cd44dfa057b66ea081be5d
ToppCelldroplet-Lung-LUNG-1m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NET1 SLC15A3 CRACD RASSF3 NFAM1 WDFY4 LPL PNPLA7

5.73e-06185231853a5218c1e6eb12daccde3d6e02f337e2586d74c
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2A2 STAB1 PTPRB NOTCH4 TNS3 GUCY1A2 CHRD LRBA

5.96e-06186231837860daeecd6d412bd3797f30496a56da667fbd1
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2A2 STAB1 PTPRB NOTCH4 TNS3 GUCY1A2 CHRD LRBA

5.96e-06186231860830822d3de3147816693404fd03392e04c2b8e
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2A2 STAB1 PTPRB NOTCH4 TNS3 GUCY1A2 CHRD LRBA

5.96e-061862318baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCellAdult-Mesenchymal-pericyte_cell|Adult / Lineage, Cell type, age group and donor

OBSCN ARHGEF17 NEURL1B UNC5D SYNM SMTN GUCY1A2 SH3RF3

6.20e-06187231862759efb660179402fb574ce5701c89a2e17bcfe
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

OBSCN ARHGEF17 AHRR SYNM SMTN GUCY1A2 LPL ADAMTS14

6.20e-061872318a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRACD PTPRB SYNJ2 NAV1 NOTCH4 EVA1C LPL ASNS

6.70e-061892318b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BCL2 SVEP1 CACNA1D SDK2 GRID2 FADS1 GUCY1A2 KIAA1755

6.96e-06190231845df8fee00f8949937863159d7aa042e72748d9b
ToppCellCF-Lymphoid-B_cell|CF / Disease state, Lineage and Cell class

MYCBP2 FCRL3 NFATC2 CNTRL WDFY4 PIKFYVE EBI3 LRBA

6.96e-061902318374d8fd63c733178acab07682ed1519693efab45
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GIPC2 CRACD PTPRB SYNJ2 NAV1 NOTCH4 EVA1C ASNS

6.96e-061902318aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 ARHGEF17 SVEP1 CRACD NEURL1B GUCY1A2 KIAA1755 SH3RF3

6.96e-06190231870c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellLV-08._Macrophage|World / Chamber and Cluster_Paper

NAIP STAB1 TNS3 PARP8 WDFY4 EBI3 IGSF21 PIK3R5

7.23e-061912318e7a0bc46ba9ba772636a583f3387748418e18832
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NET1 NGB VWA1 PDLIM4 SMTN CHRD ADAMTS14 CDH4

7.52e-06192231893903576dddd8227328e4ced75aa7625eedb9baf
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NET1 NGB VWA1 PDLIM4 SMTN CHRD ADAMTS14 CDH4

7.81e-061932318cfab88935abe0a15632c5eec8ff00a857ec9b3ed
ToppCellFetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THSD4 PTPRB ARHGAP29 NAV1 NEURL1B NOTCH4 RP1L1 SH3RF3

7.81e-061932318ad2df9b77999780860141be6ec366afc0172a331
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

MYCBP2 BCL2 FCRL3 FER RASSF3 WDFY4 PIKFYVE EBI3

7.81e-0619323187ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SVEP1 PXDNL TRHDE CACNA1D SDK2 GRID2 GUCY1A2 KIAA1755

8.11e-06194231889b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 HS6ST2 TMEM52B SCN2A ARRDC3 USP24 LPL LRBA

8.42e-061952318a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

STAB1 NFATC2 RASSF3 PARP8 CNTRL WDFY4 IGSF21 PIK3R5

8.42e-0619523187b6c69df943842b566a596e30bb50dbe80dccc83
ToppCell10x5'-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

NAIP ARHGEF17 STAB1 TDRD6 PCDHGC4 PTPRU WDFY4

9.06e-0614123177671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 SVEP1 NFATC2 TNS3 FAT4 GUCY1A2 KIAA1755 SH3RF3

9.07e-06197231885a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 SVEP1 NFATC2 TNS3 FAT4 GUCY1A2 KIAA1755 SH3RF3

9.07e-061972318e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCellASK428-Endothelial|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

GIPC2 STAB1 PTPRB ARHGAP29 NOTCH4 FAT4 SYNM SMTN

9.41e-061982318d69d0ff115298596173a4278897a65007a71f5df
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NET1 AXIN2 PTPRB ARHGAP29 VWA2 NOTCH4 SMTN SLC7A5

9.76e-061992318236b1417ed0875e98c6ec1ec714003bfce438d65
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IDI2-AS1 ST6GAL2 SCN1A SCN2A NAV1 UNC79 USP24 IGSF21

9.76e-06199231819a97e27a4758e794ce7246d295e112b47931a48
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NAIP RYR1 STAB1 NFAM1 WDFY4 EBI3 IGSF21 PIK3R5

1.01e-052002318179afc4bee7a2fd85a3b5dadf32544a63807c164
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NET1 PTPRB ARHGAP29 VWA2 NOTCH4 VWA1 SMTN SLC7A5

1.01e-05200231886ec951234015ced7126b016199e5869a0f22478
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLCXD2 BCL2 GFI1 NFATC2 NLRC3 PARP8 SLC7A5 PIK3R5

1.01e-05200231866fb892bda1d29e67a65717e85f2ec221f520b2a
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDKN2A PLCXD2 KATNIP UNC79 TG CCNF ADAMTS14

2.06e-0516023176b0faaa371650563f585722f5b2fb319e124ec38
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NET1 MYCBP2 WDFY4 WDR87 LPL RP1L1 PNPLA7

2.23e-051622317d712bc31840ad1523e3dbf884acbb428a8995001
ToppCellHealthy_Control-Lymphoid-Plasma-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PASK PKP2 PGGHG EVA1C ASNS KCNMB3 ADAMTS14

2.32e-051632317b589ff57d58dcb215ee3b5a10d81f43e5752a196
ToppCellHealthy_Control-Lymphoid-Plasma|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PASK PKP2 PGGHG EVA1C ASNS KCNMB3 ADAMTS14

2.32e-0516323172913ccdd4613472cd82077d4993e1d9f8b223398
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AHRR PTPRB HMCN2 SYNJ2 NAV1 NOTCH4 EVA1C

2.51e-051652317a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCellfacs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIPC2 EXPH5 ST14 PKP2 GRIN2D PRKDC SH3RF3

2.61e-05166231711b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCelldroplet-Lung-LUNG-1m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEXB RYR1 NFATC2 PGGHG BTBD17 WDFY4 EBI3

2.61e-051662317c215c4aede38d355d35fd26cd7ef2c19efecd0e6
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIPC2 EXPH5 ST14 PKP2 GRIN2D PRKDC SH3RF3

2.61e-051662317fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

THSD4 OBSCN ARHGAP29 NOTCH4 SYNM GIPC3 SH3RF3

2.71e-0516723175af9127bae05768a5164d5708a4ad37edca99324
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXNA1 CACNA1F NFAM1 WDFY4 PDLIM4 EBI3 LPL

2.81e-05168231704e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEXB RYR1 NFATC2 PGGHG BTBD17 WDFY4 EBI3

2.92e-051692317735655e75511c5c41aca667909e8bb52a0ad7fc6
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

THSD4 OBSCN STAB1 MYPN WDFY4 TG PIK3R5

3.04e-0517023174232fe937909f93d3736988c707b8f95ce993398
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-mature_conventional_dendritic_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ST6GAL2 NAV1 NEURL1B VWA1 PDLIM4 EBI3 ANKFN1

3.15e-051712317d934d68efc5739483c735dc702ccd30b07a6aa7e
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 HS6ST2 TMEM52B SCN2A CACNA1D USP24 LPL

3.39e-0517323170c74bdb40e635d906fd180412c23bf7fed61621e
ToppCellAdult-Mesenchymal-pericyte_cell-D175|Adult / Lineage, Cell type, age group and donor

OBSCN ARHGEF17 NEURL1B UNC5D SYNM GUCY1A2 CHRD

3.39e-051732317fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

KREMEN1 NAIP ANKAR TPGS1 EBI3 LPL

3.50e-0511823167e6cb77fa9154f2da985c455bb6a24d6029cc8d6
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EXPH5 SVEP1 AHRR PKP2 FAT4 GRIN2D NR2E1

3.93e-05177231784116796ca4c7007508c0f1a68a1135c7b922278
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRB SYNJ2 NAV1 NOTCH4 FAT4 TBC1D3L EVA1C

4.07e-0517823175f779a66aa42d1d8e8af17b4a08d5dcc733efd4c
ToppCellfacs-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF17 GPR179 NEURL1B UNC5D SDK2 SMTN GUCY1A2

4.22e-051792317d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCellfacs-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF17 GPR179 NEURL1B UNC5D SDK2 SMTN GUCY1A2

4.22e-0517923177078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GIPC2 TMEM52B ST14 TRHDE PGGHG SI AKR7A3

4.37e-0518023178d9be9cfdf98e5888654a28ab12e5e89f201af00
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

THSD4 ST6GAL2 PXDNL SYNM SMTN ZFHX3 SH3RF3

4.37e-051802317d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRACD PKP2 FAT4 SDK2 GRIN2D NR2E1 ANKFN1

4.37e-051802317b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNJ2 VWA2 SDK2 PTPRU TLE4 ZFHX3 PNPLA7

4.37e-051802317b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 SVEP1 PTPRB NAV3 NAV1 FAT4 VWA1

4.37e-05180231712537d8a569faa69f474284d2c201475722b8ca1
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRACD PKP2 FAT4 SDK2 GRIN2D NR2E1 ANKFN1

4.69e-0518223177dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCelldroplet-Liver-Npc-21m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB1 PTPRB NAV1 NOTCH4 TNS3 PCDHGA1 PTPRU

4.69e-051822317dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCelldroplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB1 PTPRB NAV1 NOTCH4 TNS3 PCDHGA1 PTPRU

4.69e-051822317010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-6_VIP_RGS16|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SVEP1 CRACD FREM2 PKP2 VWA5B1 GRID2 NR2E1

4.69e-051822317724c33ad2fb525cbcfa5efa3362675eb42a5636d
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

OBSCN ARHGEF17 UNC5D SYNM SMTN GUCY1A2 SH3RF3

4.85e-051832317fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

THSD4 PDE7A OBSCN PXDNL MYPN PKP2 LPL

5.02e-051842317ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRACD PKP2 FAT4 SDK2 GRIN2D NR2E1 ANKFN1

5.20e-05185231708fad1e3c3cc5f1c3eb6629a49c094b628e75a92
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

SVEP1 HMCN2 NAV3 NAV1 CACNA1D GUCY1A2 KIAA1755

5.20e-051852317fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCN1A UNC79 UNC5D CNTF GRIN2C ANKFN1 SPEM1

5.38e-051862317bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PTPRB HMCN2 ARHGAP29 TDRD6 NEURL1B NOTCH4 VWA1

5.38e-051862317a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCellCOVID-19_Mild-Neu_4|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

SVEP1 RECQL4 PIF1 CNTRL DUT LFNG CCNF

5.56e-051872317714851e757c71c559ee6413a3f61d6c117c79ad2
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

EXPH5 CRACD FREM2 TCF20 PGGHG TLE4 SH3RF3

5.56e-0518723177e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SVEP1 CRACD RASSF3 TNS3 SDK2 NR2E1 CDH4

5.56e-051872317d2ffb2f34f07b0dd5d3cb3ee0275f46ebecf4146
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 HS6ST2 TMEM52B SCN2A CACNA1D USP24 LRBA

5.75e-051882317bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 HS6ST2 TMEM52B SCN2A CACNA1D USP24 LRBA

5.75e-051882317eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 HS6ST2 TMEM52B SCN2A CACNA1D USP24 LRBA

5.95e-051892317975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

ARHGEF17 PXDNL ARHGAP29 NOTCH4 SYNM GUCY1A2 LPL

5.95e-0518923179c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 HS6ST2 TMEM52B SCN2A CACNA1D USP24 LRBA

5.95e-0518923177eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NET1 SLC15A3 CRACD ITPRIPL2 WDFY4 LPL PNPLA7

5.95e-051892317287e59104687fe1665232c52993889f0f2c97f17
ToppCelldroplet-Lung-LUNG-1m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NET1 SLC15A3 CRACD ITPRIPL2 WDFY4 LPL PNPLA7

5.95e-0518923176d24414ac6bd4f03f7a5ad3a6eba51d549a7b112
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 HS6ST2 TMEM52B SCN2A CACNA1D USP24 LRBA

5.95e-051892317977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 PTPRB HMCN2 SYNJ2 NAV1 NOTCH4 EVA1C

5.95e-0518923176463890d8dbee4bc198f91628a5f784970de786a
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

OBSCN ARHGEF17 SYNM SMTN GUCY1A2 LPL ADAMTS14

5.95e-051892317d7ed96add29f219183c802895fbff519b627f635
ToppCellCOVID-19-Heart-Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

NAIP RYR1 STAB1 WDFY4 IGSF21 PIK3R5 SLC38A6

5.95e-0518923172586f4088721c5debec86c2b211b739fd33713eb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST2 TMEM52B PXDNL SCN2A CACNA1D USP24 LRBA

6.15e-051902317b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellMonocytes-Tissue-resident_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

SLC15A3 STAB1 NAV1 PKP2 ITPRIPL2 ZFHX3 IGSF21

6.15e-05190231707215e8f292cb54c670037aaf28393cddbe5548c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 HS6ST2 TMEM52B SCN2A CACNA1D USP24 LRBA

6.15e-051902317e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

OBSCN PXDNL MYPN NAV1 PKP2 SYNM LPL

6.15e-051902317918ad5037881212008f9f69d5df5da91fd01422c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RYR1 STAB1 NFATC2 WDFY4 EBI3 IGSF21 PIK3R5

6.15e-051902317788ff9d8888d2dd25b7e1d7e0e5d57751ce86f19
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

ARHGEF17 PTPRB ARHGAP29 NEURL1B NOTCH4 GUCY1A2 ZFHX3

6.15e-051902317a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 SVEP1 CRACD NEURL1B GUCY1A2 ANKFN1 SH3RF3

6.35e-051912317a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLC15A3 RYR1 STAB1 GRIN2C WDFY4 EBI3 PIK3R5

6.35e-051912317c383ae386bc53e73a683a9543c7dfed2a65257c5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RYR1 STAB1 NFATC2 WDFY4 EBI3 IGSF21 PIK3R5

6.35e-051912317baa70781633a3fe5bf987f9d8dff3884f5167e7f
Drugriluzole

RYR1 ADSL NAV1 CNTF CACNA1D CACNA1F GRID2 GRIN2C GRIN2D GRM2 PDLIM4

1.29e-0617422411CID000005070
DrugC-PP

DUT GRID2 GRIN2C GRIN2D GRM2

7.20e-06282245CID000001228
DrugAC1L9828

PRPS2 DUT PRPS1

9.26e-0652243CID000439794
Drugmethyl iodoacetate

PRPS2 PRPS1L1 PRPS1

1.84e-0562243CID006429536
DrugAPP-MP

PRPS2 PRPS1L1 PRPS1

1.84e-0562243CID003081102
Drugpyrimidine-5-nucleotide

PRPS2 PRPS1L1 PRPS1

1.84e-0562243CID000440040
DrugNDPhA

CYP2E1 AHRR PLXNA3 SYNM

1.96e-05172244CID000006838
Drug1tjp

OBSCN BCL2 PKP2 DUT GRIN2C GRIN2D SMTN CHRD

1.98e-051162248CID005459371
DrugCefadroxil [50370-12-2]; Down 200; 11uM; MCF7; HT_HG-U133A

LZTR1 ABCA7 GFI1 PAOX SYNJ2 PLXNA1 IPO5 CACNA1D TAF1C TNKS2

2.26e-05193224104161_DN
DrugBaclofen (R,S) [1134-47-0]; Up 200; 18.8uM; PC3; HT_HG-U133A

CDKN2D FRS3 BCL2 SVEP1 USP19 PAOX SYNJ2 PLXNA1 CNTRL ZFHX3

2.58e-05196224106313_UP
DrugR,S)-AMPA

DUT GRID2 GRIN2C GRIN2D GRM2

2.59e-05362245CID000001221
DrugBromopride [4093-35-0]; Up 200; 11.6uM; PC3; HT_HG-U133A

MAN2A2 ARHGEF17 ARHGEF16 RYR1 STAB1 R3HCC1L PTPRB PARP8 GRM2 TLE4

2.82e-05198224104278_UP
Drugnordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A

CDKN2A ABCA7 GFI1 STAB1 KSR1 SYNJ1 SYNJ2 PKP2 TAF1C SMTN

2.82e-05198224105220_UP
Drug6-aminochrysene

CYP2E1 AHRR SYNM SLC38A6

3.15e-05192244CID000017534
DrugL-BMAA

GRID2 GRIN2C GRIN2D GRM2 SLC7A5

3.40e-05382245CID000028558
Drug4CPG

GRID2 GRIN2C GRIN2D GRM2 SLC7A5

3.40e-05382245CID000005115
DiseaseColorectal Carcinoma

ZDHHC2 ABCA3 OBSCN BCL2 AXIN2 VWA2 RNPEPL1 PARP8 GRID2 PTPRU SMTN FADS1 GUCY1A2 EIF4G1 IGSF21 PIK3R5 PRPS1

2.19e-0570221917C0009402
Diseaseautism spectrum disorder (implicated_via_orthology)

ABCA3 SCN1A SCN2A PKP2 TCF20 SLC7A5 LRBA

1.47e-041522197DOID:0060041 (implicated_via_orthology)
Diseaseneurilemmoma (is_implicated_in)

CDKN2A LZTR1

1.64e-0432192DOID:3192 (is_implicated_in)
Diseaserectum adenocarcinoma (is_marker_for)

EEF2 SLC7A5

1.64e-0432192DOID:1996 (is_marker_for)
Diseasecreatinine measurement

SPATA7 GIPC2 PDE7A OBSCN BCL2 ST14 RYR1 ADSL MYPN NLRC3 LFNG FAM135B PDLIM4 FADS1 LPL KIAA1755 ZFHX3 PNPLA7 IGSF21

1.72e-0499521919EFO_0004518
DiseaseAutoimmune thyroiditis

FCRL3 TG

3.26e-0442192C0920350
DiseaseTimothy syndrome (implicated_via_orthology)

CACNA1D CACNA1F

3.26e-0442192DOID:0060173 (implicated_via_orthology)
Diseasedysgerminoma (is_marker_for)

INHA ST14

3.26e-0442192DOID:4441 (is_marker_for)
DiseaseMalignant neoplasm of breast

CDKN2A ABCA3 NET1 OBSCN BCL2 ACY1 FCRL3 SYNJ2 ARHGAP29 ARRDC3 HERC2 FTO NOTCH4 NOA1 GRIN2D EEF2 GUCY1A2 LRBA PRPS1

4.45e-04107421919C0006142
Diseaseorofacial cleft, sex interaction measurement

EXPH5 ST14 NOTCH4 TNS3 ZFHX3

4.60e-04862195EFO_0008343, MONDO_0000358
Diseasecholelithiasis

ADSL SYNJ2 FTO FADS1 LRBA

5.11e-04882195EFO_0004799
DiseaseInsulinogenic index measurement

MYCBP2 PPIP5K2

5.40e-0452192EFO_0009961
DiseaseEndometrial Stromal Sarcoma

NUTM2A NUTM2B

5.40e-0452192C0206630
Diseaseairway responsiveness measurement

USP24 WDFY4 ANKFN1

7.27e-04242193EFO_0006897
Diseaseglioblastoma (is_implicated_in)

CDKN2A LZTR1 PTPRB

7.27e-04242193DOID:3068 (is_implicated_in)
Diseasetriacylglycerol 52:2 measurement

PTPRU TG FADS1 LPL

7.49e-04552194EFO_0010414
Diseaseearly-onset Parkinson's disease (implicated_via_orthology)

SYNJ1 SYNJ2

8.07e-0462192DOID:0060894 (implicated_via_orthology)
Diseasemuscular disease (is_implicated_in)

CPT2 LPL

8.07e-0462192DOID:0080000 (is_implicated_in)
Diseaseobesity (biomarker_via_orthology)

CDKN2A CYP2E1 BCL2 FTO FADS1 LPL

8.28e-041472196DOID:9970 (biomarker_via_orthology)
DiseaseSchizophrenia

KREMEN1 CYP2E1 RTN4R FASTKD5 BCL2 NAV1 CNTF NOTCH4 IPO5 CACNA1F GRIN2C GRIN2D GRM2 LPL NR2E1 B3GAT2

9.79e-0488321916C0036341
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

1.12e-0372192C0751057
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

1.12e-0372192C0149886
DiseaseParkinson's disease (implicated_via_orthology)

GIPC2 AXIN2 SYNJ1 SYNJ2 GIPC3 EIF4G1

1.16e-031572196DOID:14330 (implicated_via_orthology)
Diseasetumor necrosis factor receptor superfamily member 19L measurement

ARHGEF17 PIKFYVE

1.49e-0382192EFO_0008309
Diseasetriacylglycerol 54:3 measurement

MYPN FADS1 LPL

1.55e-03312193EFO_0010421
Diseaseneutrophil count

CDKN2A MYCBP2 NAIP BCL2 ABCA7 CEPT1 ADSL COX5A RRP12 CHST12 RASSF3 FTO NOTCH4 TNS3 PARP8 CRK FADS1 RP1L1 PRKDC LRBA TNKS2

1.56e-03138221921EFO_0004833
Diseasetotal cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer

FTO FADS1 LPL ZFHX3

1.75e-03692194EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
DiseaseAdenocarcinoma

CDKN2A CYP2E1 BCL2 FAT4 EEF2

1.77e-031162195C0001418
DiseaseCarcinoma, Granular Cell

CDKN2A CYP2E1 BCL2 FAT4 EEF2

1.77e-031162195C0205644
DiseaseAdenocarcinoma, Tubular

CDKN2A CYP2E1 BCL2 FAT4 EEF2

1.77e-031162195C0205645
DiseaseAdenocarcinoma, Oxyphilic

CDKN2A CYP2E1 BCL2 FAT4 EEF2

1.77e-031162195C0205642
DiseaseCarcinoma, Cribriform

CDKN2A CYP2E1 BCL2 FAT4 EEF2

1.77e-031162195C0205643
DiseaseAdenocarcinoma, Basal Cell

CDKN2A CYP2E1 BCL2 FAT4 EEF2

1.77e-031162195C0205641
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A

1.91e-0392192C3502809
DiseaseFebrile Convulsions

SCN1A SCN2A

1.91e-0392192C0009952
DiseaseMyoclonic Epilepsy

HEXB SCN1A

1.91e-0392192C0014550
Diseaseglycoprotein measurement

DHODH POM121L2 LPL ZFHX3 CDH4

1.98e-031192195EFO_0004555
DiseaseGrey matter density measurement

SCN1A KATNIP GUCY1A2

2.04e-03342193EFO_0010306
DiseaseSpinocerebellar Ataxia Type 4

GFI1 PLEKHG4 GRID2

2.22e-03352193C0752122
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN2A

2.37e-03102192DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN2A

2.37e-03102192DOID:0080422 (implicated_via_orthology)
Diseaseglaucoma (is_implicated_in)

CNTF EEF2

2.37e-03102192DOID:1686 (is_implicated_in)
Diseaseurate measurement, bone density

THSD4 NAV1 FTO NOTCH4 GRIN2C THAP9 TG KIAA1755 PRKDC CDH4 SH3RF3 B3GAT2

2.41e-0361921912EFO_0003923, EFO_0004531
Diseasecolorectal carcinoma (is_marker_for)

SELENOS AXIN2 PTPRB

2.60e-03372193DOID:0080199 (is_marker_for)
Diseasegranulosa cell tumor (is_marker_for)

CDKN2A ST14

2.89e-03112192DOID:2999 (is_marker_for)
DiseaseBipolar I disorder

BCL2 NR2E1

2.89e-03112192C0853193
Diseasepolybrominated biphenyl measurement, gestational serum measurement, fetal genotype effect measurement, polybrominated diphenyl ether measurement

LCLAT1 ZFHX3

2.89e-03112192EFO_0007959, EFO_0007961, EFO_0007962, EFO_0007964
Diseasecysteine-glutathione disulfide measurement

NFAM1 SH3RF3

2.89e-03112192EFO_0021001
DiseaseNight blindness, congenital stationary, type 1

GPR179 CACNA1F

3.45e-03122192C3501847
Diseasemetabolite measurement, body weight gain

FADS1 ZFHX3

3.45e-03122192EFO_0004566, EFO_0004725
DiseaseNight Blindness, Congenital Stationary, Type 1A

GPR179 CACNA1F

3.45e-03122192C3495587
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)

GPR179 CACNA1F

3.45e-03122192C1864877
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN2A

3.45e-03122192DOID:0060170 (implicated_via_orthology)
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B

GPR179 CACNA1F

3.45e-03122192C1850362
DiseaseX-Linked Csnb

GPR179 CACNA1F

3.45e-03122192C3711543
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A

GPR179 CACNA1F

3.45e-03122192C1848172
DiseaseAgents acting on the renin-angiotensin system use measurement

SVEP1 NFATC2 FTO SAP130 CNTF CACNA1D LFNG CRK

3.71e-033352198EFO_0009931
Diseasepulse pressure measurement

THSD4 SVEP1 NFATC2 PXDNL MYPN FER NAV1 NEURL1B FTO PIF1 TNS3 CACNA1D CNTRL CRK EVA1C FADS1 MEGF8 LPL KIAA1755 ZFHX3

3.79e-03139221920EFO_0005763
Diseasefatty acid measurement, fetal genotype effect measurement, breast milk measurement

FAM135B FADS1

4.05e-03132192EFO_0005110, EFO_0007959, EFO_0009092
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A

4.05e-03132192C0751122
DiseaseCone-rod synaptic disorder, congenital nonprogressive

GPR179 CACNA1F

4.05e-03132192C4041558
Diseasecognitive impairment measurement

PXDNL NAV3 SH3RF3

4.27e-03442193EFO_0007998
Diseasemean arterial pressure

SVEP1 NFATC2 PXDNL FTO MOV10 CACNA1D TCF20 IKZF4 ZFHX3 LRBA

4.33e-0349921910EFO_0006340
Diseaselobe attachment

PLCXD2 NFATC2 FAT4 PRKDC LRBA ADAMTS14

4.62e-032072196EFO_0007667
Diseasefatty acid measurement, breast milk measurement, parental genotype effect measurement

FAM135B FADS1

4.71e-03142192EFO_0005110, EFO_0005939, EFO_0009092
Diseaselysophosphatidylcholine 22:5 measurement

NFATC2 FADS1

4.71e-03142192EFO_0021462
Diseaseamino acid measurement

RTN4R AXIN2 PASK PTPRB NAV3 UNC5D IPO5 FAT4 RP1L1 PRKDC LRBA TNKS2

4.97e-0367821912EFO_0005134
Diseasecaudate nucleus measurement, functional brain measurement, response to reward

SPACA6 TRHDE FAM135B

5.14e-03472193EFO_0007849, EFO_0008387, EFO_0008396
DiseaseAutosomal recessive primary microcephaly

WDR62 CEP152

5.40e-03152192cv:C3711387
Diseaselevel of Triacylglycerol (53:3) in blood serum

FADS1 LPL

5.40e-03152192OBA_2045165
DiseaseSinus Node Dysfunction (disorder)

PKP2 CACNA1D

5.40e-03152192C0428908
DiseaseDown syndrome (implicated_via_orthology)

SYNJ1 SYNJ2

5.40e-03152192DOID:14250 (implicated_via_orthology)
DiseaseMMR-related febrile seizures

SCN1A SCN2A

5.40e-03152192EFO_0006519
Diseasecis/trans-18:2 fatty acid measurement, trans fatty acid measurement

FADS1 CDH4

5.40e-03152192EFO_0006821, EFO_0006824
Diseasehepatoblastoma (is_marker_for)

AXIN2 ZFHX3

5.40e-03152192DOID:687 (is_marker_for)
Diseasehigh density lipoprotein cholesterol measurement, metabolic syndrome

FADS1 LPL

5.40e-03152192EFO_0000195, EFO_0004612
Diseasefat body mass

THSD4 ABCA3 MYCBP2 SCN2A FTO FAM135B

5.79e-032172196EFO_0005409
Diseasecognitive inhibition measurement

PXDNL PIF1 TCF20

6.12e-03502193EFO_0007969
Diseaseresponse to hydrochlorothiazide, systolic blood pressure change measurement

ZDHHC2 TAF1C

6.14e-03162192EFO_0005202, EFO_0006944
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A

6.14e-03162192C0393706
Diseasediacylglycerol 36:2 measurement

FADS1 LPL

6.14e-03162192EFO_0010355
Diseasemean arterial pressure, alcohol drinking

COX5A FTO MOV10 RP1L1

6.19e-03982194EFO_0004329, EFO_0006340
Diseaseprostate cancer (is_marker_for)

CDKN2A INHA BCL2 ADSL EEF2

6.28e-031562195DOID:10283 (is_marker_for)
Diseasevascular endothelial function measurement

ZDHHC2 FRS3 GRID2 CDH4

6.42e-03992194EFO_0803369
Diseasesevere acute respiratory syndrome, COVID-19

THSD4 KSR1 SYNJ2 FER RASSF3 WDFY4 TG GCNT7 ZFHX3

6.46e-034472199EFO_0000694, MONDO_0100096
Diseasetotal cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement

FTO FADS1 LPL

6.46e-03512193EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Diseaseperiodontitis

THSD4 HS6ST2 SCN2A FTO FAM135B ZFHX3

6.58e-032232196EFO_0000649
DiseaseVitiligo

HERC2 IKZF4 TG FADS1

6.88e-031012194EFO_0004208
DiseaseNight blindness, congenital stationary

GPR179 CACNA1F

6.93e-03172192C0339535
DiseaseHypermetropia

CHST12 GRIN2C PTPRU ANKFN1

7.36e-031032194HP_0000540

Protein segments in the cluster

PeptideGeneStartEntry
HGERRFLGVTQFSPT

TRHDE

256

Q9UKU6
HSRGFIESIRPALEL

NAIP

1036

Q13075
HGRATAGRSRELTPF

AHRR

601

A9YTQ3
DRTTAAHGLELRVPF

ASNS

406

P08243
LSFDSREASFVHGRP

CEP152

1581

O94986
RSGLHKLFPSRDADS

CNTRL

1206

Q7Z7A1
PTSAAVTRAFLERGH

AKR7L

26

Q8NHP1
PTSAAVTRAFLERGH

AKR7A3

26

O95154
VLLPTHRRRGSFSSE

ALKBH5

351

Q6P6C2
VSHRAPTSRFGSAAA

GRM2

826

Q14416
FSINHATGEIRSVRP

FAT4

2716

Q6V0I7
RSAALARHGPAVADL

BTBD17

271

A6NE02
TPARHQSFGAAVLSR

ARHGEF16

101

Q5VV41
AGLTPEERSFHTSRN

CLK3

621

P49761
GAELSFILPRESTHR

ABCA3

791

Q99758
LESARSSPGERASRH

AXIN2

646

Q9Y2T1
SLSASRAPARRLVFH

GIPC2

31

Q8TF65
RLVFRTQLAHGSPTG

GIPC3

36

Q8TF64
SSGARHRLPRELIFV

CEP170B

11

Q9Y4F5
SPVHDAARTGFLDTL

CDKN2D

76

P55273
PLLLRRHFGSSDTFS

DMXL1

1821

Q9Y485
TPLATSFEGRHGSVR

ARRDC3

121

Q96B67
TDFRGRFLSHVVSGP

ADAMTS14

46

Q8WXS8
RFLSHVVSGPAAASA

ADAMTS14

51

Q8WXS8
FAAGHTLTLRVPAAR

ABCA7

2016

Q8IZY2
TAAFKHGRTETIRPA

CPT2

491

P23786
RHGVFLVRDSSTSPG

CRK

31

P46108
HALGVFSSPITARDA

R3HCC1L

681

Q7Z5L2
AGPRTDTLSFVLREH

RASSF3

171

Q86WH2
SNLPHEATRDTIFRG

CYP2E1

366

P05181
LRGASIFSLTAHDPD

PCDHGA8

466

Q9Y5G5
IFPSRRNEVRTHVGS

GRSF1

321

Q12849
QSFTLRGDHRSPASA

NET1

121

Q7Z628
RHRAATSEEPTGFSV

ARHGEF17

741

Q96PE2
AHSRAGIPEAFTTLG

ANKAR

1241

Q7Z5J8
VSLAAEDPIRAHSFR

CACNA1F

886

O60840
NTHRRGSGALIFTIP

CACNA1F

1716

O60840
FRVHIPESSGRIVSL

NFATC2

546

Q13469
FIFGRTVPASVSHLR

PTPRB

1166

P23467
SHRTFGRSLSSDPRA

PARP8

336

Q8N3A8
ARTRLFLASLPGSTH

PASK

941

Q96RG2
AAAPGALVRDVHSLS

LFNG

61

Q8NES3
ASELPSGRLFHAAAV

LZTR1

381

Q8N653
ALARLTGPAHRAALA

NLRC3

591

Q7RTR2
EVHVRRSHSGTRPFA

GFI1

271

Q99684
FRLHSATLAPIGSRG

NUDT22

61

Q9BRQ3
FPEALARQHSRDSGS

GPR179

726

Q6PRD1
PALGFRSASAHNLTV

GPR179

811

Q6PRD1
LRSITHSFVGRPSEG

HERC2

2171

O95714
ASRLDFSPDVRSHLA

KIAA1755

796

Q5JYT7
AGSQPRFSSTHRVAE

FTO

311

Q9C0B1
VFPLRESHTLTVREG

HMCN2

2171

Q8NDA2
FDRSHRGRISNTELP

KATNIP

906

O60303
PFTRGRSHSITIDFT

KATNIP

1051

O60303
TGRSFAVHTRRENPA

ASPDH

236

A6ND91
ADHPGLTFSLRLIRS

FREM2

2771

Q5SZK8
LHPRTTGFTFVVDRL

LCLAT1

231

Q6UWP7
AVLLPASRFLSVHTR

DCAF4L1

156

Q3SXM0
HLFIQRSTAGTPRSG

GRID2

116

O43424
IFSTAHRGSALPLAI

PLXNA1

1701

Q9UIW2
VFSTAHRGSALPLAI

PLXNA3

1676

P51805
ASGRLTPRALHSFIT

KSR1

256

Q8IVT5
VHNFPGTSRRLSALG

KPTN

206

Q9Y664
VDVLHTFTRGSPGRS

LPL

206

P06858
VPQHVLSRRGAISFS

PDE7A

16

Q13946
ATSLEERPRAISHSG

NAV3

1521

Q8IVL0
ERPRAISHSGSFRDS

NAV3

1526

Q8IVL0
ITFSGRPSRVHASEV

FBXO39

61

Q8N4B4
AHITLRTGAFTDAGP

MEX3D

336

Q86XN8
HNVSARDPAFSARIG

MEGF8

216

Q7Z7M0
SSRLFFVGSREGHLP

SLC7A5

346

Q01650
VDFAPFLSRTLLGSH

LRBA

1816

P50851
HRPVTATSAGRARVL

LINGO3

446

P0C6S8
RQRSALPATGHFTAR

EXPH5

326

Q8NEV8
TFKSHRVPASGDLRD

KREMEN1

416

Q96MU8
TGSFLHTLEGPRFRA

PGGHG

86

Q32M88
FSGHTPDRVRNLFSL

PCDHGC4

281

Q9Y5F7
FARLSEHATAPTRGS

DUT

116

P33316
HPSIRTLSARATAAF

IPO5

186

O00410
FATALDTTRHELPVR

HAUS8

236

Q9BT25
RSRLGSHPLLFSGEV

DXO

221

O77932
STILRLPAAAFHGVF

PNPLA7

241

Q6ZV29
SHRRFLATFPLAAVS

PTPRU

241

Q92729
HSAPFVARALRIRSS

PPP1R37

206

O75864
HFLLRPTSIRVREGS

OBSCN

111

Q5VST9
RFHRLILTPATFSGL

GLYATL3

271

Q5SZD4
HTVPALSTARFSDGR

PXDNL

816

A1KZ92
RSLDSESISPGDFHR

ARHGAP29

551

Q52LW3
TFGGHDPRTAVQLRS

PIKFYVE

116

Q9Y2I7
RAHPERAALLFVSSV

EVA1C

316

P58658
ATLTRPVHDAAREGF

CDKN2A

76

P42771
RRTNSSSPLGELFDH

CEPT1

141

Q9Y6K0
RRILTTSSAHPGLEF

FASTKD5

66

Q7L8L6
FLRHSRTPSSDGTVE

IGSF21

286

Q96ID5
GEIHAFLSSPSGRRT

CCNF

556

P41002
ISRGLHFITRPLSAE

GCNT7

91

Q6ZNI0
FESIRHSIAGIIRSP

FER

421

P16591
TRAAIRSHGSFPVPL

FRS3

376

O43559
VSRFLARAGLPSTHL

B3GAT2

126

Q9NPZ5
LRFISSHQTGIPARG

CNTF

176

P26441
RPKRHFSSAGTIESV

CRACD

126

Q6ZU35
EGTRFLHGARLSPLS

IDI2-AS1

71

Q9NZ38
RFHRVGPIEATSFIL

EBI3

176

Q14213
LAHISGASSFEPRSL

DDX50

566

Q9BQ39
RIISGDPSGHFSVRT

CDH4

431

P55283
SEFTRRHPGGSRVIS

FADS1

46

O60427
SPSLLFIFVRHGVES

EIF4G1

1271

Q04637
TFRAPRAHTVVGDLL

FCRL3

386

Q96P31
SRHEAFPLRVIDSGT

MAN2A2

746

P49641
SARPEATPFLVAHTR

INHA

206

P05111
FILLTRHRTAFPASG

KCNMB3

16

Q9NPA1
HSRVEAELAASRPGS

HS6ST2

31

Q96MM7
ALVPRAFHASAVGLR

COQ9

31

O75208
PGHVDFSSEVTAALR

EEF2

106

P13639
VSSRIPHRLSASIAG

FAM135B

36

Q49AJ0
ESTIIDSPRFSHRGI

HEXB

191

P07686
DSPRFSHRGILIDTS

HEXB

196

P07686
RIPAHRFVLAVGSAV

BTBD2

131

Q9BX70
VAATTRADPRGLLHS

COX5A

11

P20674
ASQGPASHSRFSRDR

SLC15A3

566

Q8IY34
HGEAAVIRAPRIASF

SDK2

126

Q58EX2
ARIRPAQLTHRGTFS

SPACA6

211

W5XKT8
RHRVSLFGTDAPAVV

RYR1

3051

P21817
AALAAEDPIRSHSFR

CACNA1D

901

Q01668
EDPIRSHSFRNTILG

CACNA1D

906

Q01668
SSLAFVGAEHLRPLR

IKZF4

371

Q9H2S9
VSRSPLEHGTVLFAR

NGB

16

Q9NPG2
LSLFLRGSAPTAARH

NOA1

11

Q8NC60
FPRAASTTRTQHRGE

LRRN4

446

Q8WUT4
AVPTHSGSELRSFRN

NR2E1

296

Q9Y466
PRGASIFSVRAHDLD

PCDHGA1

466

Q9Y5H4
SAFPHLRVLEATARA

PAOX

36

Q6QHF9
AFSSRHFREPGLSIL

ITPRIPL2

86

Q3MIP1
VTLASKFESGSHPRR

GUCY1A2

641

P33402
HARAAPSRGTARLDS

NUTM2A

631

Q8IVF1
HARAAPSRGTARLDS

NUTM2B

631

A6NNL0
SSPRRSLGLALTHSF

NAV1

1381

Q8NEY1
PVRFTISSRTDAGVH

PUSL1

56

Q8N0Z8
LAPLSSSRSRFHAFI

RUSC1

586

Q9BVN2
SSVPERAFRGLHSLD

RTN4R

191

Q9BZR6
AEAGRSTLRLPAHDT

PIF1

81

Q9H611
FTPLARHRTLTAEEA

GTF2F1

146

P35269
LATHRAFTSTPALLG

RGL2

121

O15211
HSAAFRRAPAAAAET

RNPEPL1

86

Q9HAU8
SANPGRFHTSERIRG

TRMT1

416

Q9NXH9
GASLALRVSFVDVHP

TDRD6

11

O60522
HIAIRGPVSRTFVLA

SYNM

1416

O15061
RAGVISAPQSHARAS

SYNJ1

1201

O43426
LEAVGEFRHRSPSRS

SYNJ2

1081

O15056
ESRPSVLRGDHLFAL

MOV10

386

Q9HCE1
RSRASIAVAPFDHDS

PLEKHG4

1076

Q58EX7
SSRAVARIFHGIGSP

RECQL4

1156

O94761
ADFTAHPRVLTVGDR

TAF1C

391

Q15572
PHSTVRGSGTFILVR

NFAM1

136

Q8NET5
RDFSAPLTISRVHAG

PDLIM4

21

P50479
AKERASLPTLGFTHF

ADSL

146

P30566
AGHLTRAVEPLRTFS

NAGPA

91

Q9UK23
PESAHRLAVRFTSLG

DHODH

51

Q02127
ELHRQRSPGVSFGLS

SLC38A6

36

Q8IZM9
SHDAVLRFNSAPTRG

ST6GAL2

316

Q96JF0
FVAKDSAGLRIRSHP

MYCBP2

2471

O75592
FPELTKRTDGLHFRT

SI

1421

P14410
PGSFIVRDSHSFRGA

TNS3

1191

Q68CZ2
EHPAERVRSAFAAPS

TBC1D3L

496

B9A6J9
AILTHGIFSGPAISR

PRPS1L1

246

P21108
ARRALHEDLPSGSFI

SVEP1

256

Q4LDE5
VGTGETPLHLAARFS

NOTCH4

1631

Q99466
HTVTTRFILLGFPTR

OR6Y1

11

Q8NGX8
RSHFTRPAGVSSAVI

URB1

1281

O60287
RSVAEHPLSRAEAAG

URB1

2106

O60287
LPSHRTAFSLGRGSI

POM121L2

946

Q96KW2
AVIPEFSRHRSSGRI

SPEM1

246

Q8N4L4
SLFHARPGLSTLSAE

RRP12

351

Q5JTH9
ASEHSREPSAAGRLS

SCN1A

466

P35498
TPAHEVGRRTSVLFS

BRPF1

881

P55201
SSQLHLTPFTARGRF

BCL2

116

P10415
VRVTSTGRPGHASRF

ACY1

196

Q03154
TGARESPHFVSLESR

ANKFN1

196

Q8N957
HTSLPASAREAFRAG

CHST12

281

Q9NRB3
PLIRHRALAAETFSA

CHRD

271

Q9H2X0
RPALETEGLRFLHTT

SELENOS

11

Q9BQE4
EHPAERVRSAFAAPS

TBC1D3B

496

A6NDS4
EHPAERVRSAFAAPS

TBC1D3H

496

P0C7X1
APRGLSSEARASLHQ

RINL

516

Q6ZS11
LRASLVHVGSRPYTE

VWA1

71

Q6PCB0
ITGSRHRTRLFFPSS

USP19

71

O94966
ASGPALSRHLLTSFV

PIK3R5

366

Q8WYR1
FGVRSVTTPRGLHSL

RP1L1

76

Q8IWN7
VLSRERGLSFHQFPT

THAP9

16

Q9H5L6
EHPAERVRSAFAAPS

TBC1D3F

496

A6NER0
PLRIRFATHGAALTV

PSPC1

146

Q8WXF1
VSTRAALVPAAAGFH

SLC26A1

596

Q9H2B4
SVSPSASFRGAEKHR

TLE4

206

Q04727
SRGSFHVSQAILTPR

PLCXD2

256

Q0VAA5
QIRLHATGFRDPSTE

TAS2R9

211

Q9NYW1
SSDPRAAARIGDLAH

SH3RF3

411

Q8TEJ3
APSFEGGSRRLSHSL

PLCH2

1266

O75038
AILTHGIFSGPAISR

PRPS2

246

P11908
LITNTERRHPGFEAT

ST14

316

Q9Y5Y6
AERSSLIPISGHRAS

SAP130

451

Q9H0E3
RFHATRGPDVSLSAD

NEURL1B

281

A8MQ27
RFSSPHQSLLSIRGS

SCN2A

551

Q99250
SVFGPAARRILAVAH

TMEM52B

106

Q4KMG9
ERVRVGAFQFSSTPH

VWA2

86

Q5GFL6
TSGSPLHSRLIRIFE

WDFY4

896

Q6ZS81
GVRVFHSSPAASSLD

WDFY4

1356

Q6ZS81
FPSSFRIHERTHTGE

ZNF627

346

Q7L945
FARSLVPSSERLHLS

SPATA7

146

Q9P0W8
ALSGHPLRFSEREGS

STAB1

1666

Q9NY15
EHPAERVRSAFAAPS

TBC1D3E

496

A0A087X179
VHGSSRLEEFSPRQA

TCF20

21

Q9UGU0
LPTRTELRTTGVFGH

UNC5D

536

Q6UXZ4
SRDTAGRKSTPLHFA

TNKS2

51

Q9H2K2
AVPSAGLRLFALHAS

PRKDC

266

P78527
FRVSHSPLLEAEAGR

nan

141

Q8IYB0
PVEESALRLHGSAFR

WDR62

1326

O43379
FRASRIILNSHSPAG

USP24

1601

Q9UPU5
AILTHGIFSGPAISR

PRPS1

246

P60891
EHPAERVRSAFAAPS

TBC1D3D

496

A0A087WVF3
STLEAFRSPVFRHGT

ZDHHC2

241

Q9UIJ5
RSPFGHREAAADVSV

VSIG10L

381

Q86VR7
GSAVKRFSISFARHP

PPIP5K2

1101

O43314
PARAFADHVVSAVRT

THSD4

96

Q6ZMP0
VLGSHERGPSLSFRS

RIPOR1

26

Q6ZS17
EHPAERVRSAFAAPS

TBC1D3G

496

Q6DHY5
EHPAERVRSAFAAPS

TBC1D3

496

Q8IZP1
RDHEAVPLSVFRAGT

TPGS1

171

Q6ZTW0
TIRFLQGDHFGTSPR

TG

1421

P01266
RSRPEAHTLLTAGSD

WDR87

251

Q6ZQQ6
HSTRTLREAGPSVAV

PKP2

296

Q99959
PSVAVDSSGRRAHLT

PKP2

306

Q99959
PSSFQRAGSVRDRVH

SMTN

321

P53814
EHPAERVRSAFAAPS

TBC1D3K

496

A0A087X1G2
EHPAERVRSAFAAPS

TBC1D3I

496

A0A087WXS9
EHPAERVRSAFAAPS

TBC1D3C

496

Q6IPX1
RHPLGSQRVSLSFSV

SIGLEC16

411

A6NMB1
TALFSEARSPGREKH

VWA5B1

971

Q5TIE3
LAGLSPVLHSFRVFD

ZFHX3

221

Q15911
RREGVPAHVNLSASS

UNC79

211

Q9P2D8
NEPRSSSRIGLRVHF

MYPN

586

Q86TC9
RPRHASLPSSVAEAF

GRIN2C

1076

Q14957
SFVAVTTRAPGHRAF

GRIN2D

186

O15399