Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionandrosterone dehydrogenase activity

RDH16 HSD17B6 RDH5

2.09e-068683GO:0047023
GeneOntologyMolecularFunctionandrostan-3-alpha,17-beta-diol dehydrogenase activity

RDH16 HSD17B6 RDH5

3.13e-069683GO:0047044
GeneOntologyMolecularFunctionglycosylceramidase activity

GBA3 LCT

1.14e-052682GO:0017042
GeneOntologyMolecularFunction11-cis-retinol dehydrogenase

RDH16 RDH5

1.14e-052682GO:0106429
GeneOntologyMolecularFunctionglucosylceramidase activity

GBA3 LCT

6.83e-054682GO:0004348
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NAD+) activity

RDH16 HSD17B6 RDH5

7.26e-0524683GO:0004745
GeneOntologyMolecularFunctionalcohol dehydrogenase (NAD+) activity

RDH16 HSD17B6 RDH5

9.28e-0526683GO:0004022
GeneOntologyMolecularFunctiongalactosylceramidase activity

GBA3 LCT

1.14e-045682GO:0004336
GeneOntologyMolecularFunctionalcohol dehydrogenase [NAD(P)+] activity

RDH16 HSD17B6 RDH5

1.44e-0430683GO:0018455
GeneOntologyMolecularFunctionbeta-glucosidase activity

GBA3 LCT

1.70e-046682GO:0008422
GeneOntologyMolecularFunctionsteroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

RDH16 HSD17B6 RDH5

1.92e-0433683GO:0033764
GeneOntologyMolecularFunctionsteroid dehydrogenase activity

RDH16 HSD17B6 RDH5

3.16e-0439683GO:0016229
GeneOntologyMolecularFunctionglucosidase activity

GBA3 LCT

1.17e-0315682GO:0015926
GeneOntologyMolecularFunctionC2H2 zinc finger domain binding

GATA1 GATA2

1.50e-0317682GO:0070742
GeneOntologyBiologicalProcesseosinophil fate commitment

GATA1 GATA2

1.14e-052702GO:0035854
GeneOntologyBiologicalProcessoligosaccharide catabolic process

GBA3 NEU4 LCT

2.03e-0516703GO:0009313
GeneOntologyBiologicalProcessregulation of primitive erythrocyte differentiation

GATA1 GATA2

3.40e-053702GO:0010725
GeneOntologyBiologicalProcessglycosphingolipid catabolic process

GBA3 NEU4 LCT

7.20e-0524703GO:0046479
GeneOntologyBiologicalProcessceramide catabolic process

GBA3 NEU4 LCT

9.20e-0526703GO:0046514
GeneOntologyBiologicalProcessglycolipid catabolic process

GBA3 NEU4 LCT

1.03e-0427703GO:0019377
MousePhenopremature cranial synchondrosis closure

PKD1 PFAS

3.60e-053492MP:0030444
DomainTF_GATA-2/3

GATA1 GATA2

4.14e-053702IPR016374
DomainGlyco_hydro_1_N_CS

GBA3 LCT

8.27e-054702IPR033132
DomainGlyco_hydro_1_AS

GBA3 LCT

8.27e-054702IPR018120
DomainREJ

PKD1L1 PKD1

8.27e-054702PS51111
DomainREJ_dom

PKD1L1 PKD1

8.27e-054702IPR014010
DomainGLYCOSYL_HYDROL_F1_2

GBA3 LCT

1.37e-045702PS00653
DomainGLYCOSYL_HYDROL_F1_1

GBA3 LCT

1.37e-045702PS00572
DomainGlyco_hydro_1

GBA3 LCT

1.37e-045702PF00232
DomainGlyco_hydro_1

GBA3 LCT

1.37e-045702IPR001360
DomainPKD/REJ-like

PKD1L1 PKD1

2.06e-046702IPR002859
DomainREJ

PKD1L1 PKD1

2.06e-046702PF02010
DomainPKD

PKD1L1 PKD1

2.87e-047702PF00801
DomainPKD/Chitinase_dom

PKD1L1 PKD1

4.90e-049702IPR022409
DomainPKD

PKD1L1 PKD1

4.90e-049702SM00089
DomainPKD

PKD1L1 PKD1

7.45e-0411702PS50093
DomainPKD_dom

PKD1L1 PKD1

7.45e-0411702IPR000601
DomainPKD_channel

PKD1L1 PKD1

7.45e-0411702PF08016
DomainPKD1_2_channel

PKD1L1 PKD1

7.45e-0411702IPR013122
Domain-

PKD1L1 PKD1

7.45e-04117022.60.40.670
DomainZnF_GATA

GATA1 GATA2

8.92e-0412702SM00401
DomainADH_SHORT

RDH16 HSD17B6 RDH5

1.03e-0353703PS00061
Domainadh_short

RDH16 HSD17B6 RDH5

1.15e-0355703PF00106
DomainSDR_fam

RDH16 HSD17B6 RDH5

1.21e-0356703IPR002347
DomainZnf_GATA

GATA1 GATA2

1.41e-0315702IPR000679
DomainGATA

GATA1 GATA2

1.41e-0315702PF00320
DomainGATA_ZN_FINGER_1

GATA1 GATA2

1.61e-0316702PS00344
DomainGATA_ZN_FINGER_2

GATA1 GATA2

1.61e-0316702PS50114
DomainLH2

PKD1L1 PKD1

2.04e-0318702SM00308
DomainPLAT

PKD1L1 PKD1

2.78e-0321702PS50095
Domain-

PKD1L1 PKD1

2.78e-03217022.60.60.20
DomainPLAT

PKD1L1 PKD1

2.78e-0321702PF01477
DomainPLAT/LH2_dom

PKD1L1 PKD1

2.78e-0321702IPR001024
Domainfn3

LRFN4 COL12A1 PHYHIP CDON

3.21e-03162704PF00041
DomainADAM_spacer1

ADAMTS9 ADAMTS5

3.33e-0323702IPR010294
DomainADAM_spacer1

ADAMTS9 ADAMTS5

3.33e-0323702PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS9 ADAMTS5

3.62e-0324702IPR013273
DomainFN3

LRFN4 COL12A1 PHYHIP CDON

5.14e-03185704SM00060
DomainFN3

LRFN4 COL12A1 PHYHIP CDON

6.63e-03199704PS50853
DomainSc_DH/Rdtase_CS

RDH16 HSD17B6

7.61e-0335702IPR020904
Domain-

GBA3 LCT

7.61e-03357023.20.20.80
DomainFN3_dom

LRFN4 COL12A1 PHYHIP CDON

7.86e-03209704IPR003961
DomainGPS

PKD1L1 PKD1

8.03e-0336702PS50221
DomainGPS

PKD1L1 PKD1

8.47e-0337702IPR000203
DomainGlyco_hydro_catalytic_dom

GBA3 LCT

8.92e-0338702IPR013781
DomainPeptidase_M12B_N

ADAMTS9 ADAMTS5

9.38e-0339702IPR002870
DomainPep_M12B_propep

ADAMTS9 ADAMTS5

9.38e-0339702PF01562
DomainDISINTEGRIN_1

ADAMTS9 ADAMTS5

9.85e-0340702PS00427
DomainReprolysin

ADAMTS9 ADAMTS5

9.85e-0340702PF01421
DomainADAM_MEPRO

ADAMTS9 ADAMTS5

9.85e-0340702PS50215
PathwayREACTOME_THE_CANONICAL_RETINOID_CYCLE_IN_RODS_TWILIGHT_VISION

RDH16 HSD17B6 RDH5

4.06e-0520483MM14888
PathwayREACTOME_THE_CANONICAL_RETINOID_CYCLE_IN_RODS_TWILIGHT_VISION

RDH16 HSD17B6 RDH5

6.25e-0523483M27174
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

KANSL3 SHROOM3 B4GALNT4 ABR ZBED4 CSPG4 PKD1 SEC16A GATA2 NADK LMTK2 MUS81 DISP2 PFAS PLA2G6 CEP131 BIRC6 CEP170B FANCA

5.39e-131105711935748872
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

SHROOM3 CAMKK1 SEC16A NADK CEP131 BIRC6 CEP170B EIF4E2

3.61e-0644671824255178
Pubmed

Lentiviral shRNA knock-down of ADAMTS-5 and -9 restores matrix deposition in 3D chondrocyte culture.

ADAMTS9 ADAMTS5

4.11e-06271220568084
Pubmed

Essential and instructive roles of GATA factors in eosinophil development.

GATA1 GATA2

4.11e-06271212045236
Pubmed

Hemoglobin stimulates the expression of ADAMTS-5 and ADAMTS-9 by synovial cells: a possible cause of articular cartilage damage after intra-articular hemorrhage.

ADAMTS9 ADAMTS5

4.11e-06271229137610
Pubmed

GATA-2 reinforces megakaryocyte development in the absence of GATA-1.

GATA1 GATA2

4.11e-06271219620289
Pubmed

Overexpression of human GATA-1 and GATA-2 interferes with spine formation and produces depressive behavior in rats.

GATA1 GATA2

4.11e-06271225340772
Pubmed

Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis.

GATA1 GATA2

4.11e-06271226766440
Pubmed

Roles of hematopoietic transcription factors GATA-1 and GATA-2 in the development of red blood cell lineage.

GATA1 GATA2

4.11e-06271212432220
Pubmed

Context-dependent GATA factor function: combinatorial requirements for transcriptional control in hematopoietic and endothelial cells.

GATA1 GATA2

4.11e-06271217347142
Pubmed

Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy.

GATA1 GATA2

4.11e-06271219941826
Pubmed

[Expression of GATA-1 and GATA-2 in the bone marrow of patients with Monge's disease].

GATA1 GATA2

4.11e-06271218078130
Pubmed

Functional overlap of GATA-1 and GATA-2 in primitive hematopoietic development.

GATA1 GATA2

4.11e-06271214504093
Pubmed

Differential GATA factor stabilities: implications for chromatin occupancy by structurally similar transcription factors.

GATA1 GATA2

4.11e-06271218154321
Pubmed

Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis.

GATA1 GATA2

4.11e-06271222383799
Pubmed

GATA-1 and GATA-2 gene expression is related to the severity of dysplasia in myelodysplastic syndrome.

GATA1 GATA2

4.11e-06271212145700
Pubmed

GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling.

GATA1 GATA2

4.11e-06271212857954
Pubmed

Decreased mRNA expression of GATA1 and GATA2 is associated with tumor aggressiveness and poor outcome in clear cell renal cell carcinoma.

GATA1 GATA2

4.11e-06271225230694
Pubmed

GATA factor switching from GATA2 to GATA1 contributes to erythroid differentiation.

GATA1 GATA2

4.11e-06271223911012
Pubmed

Deglycosylation by small intestinal epithelial cell beta-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans.

GBA3 LCT

4.11e-06271212594539
Pubmed

GATA factor mutations in hematologic disease.

GATA1 GATA2

4.11e-06271228179280
Pubmed

ADAMTS: novel proteases expressed by activated mast cells.

ADAMTS9 ADAMTS5

4.11e-06271223154421
Pubmed

Interaction of 11-cis-retinol dehydrogenase with the chromophore of retinal g protein-coupled receptor opsin.

RDH5 RGR

4.11e-06271211274198
Pubmed

Progenitor stage-specific activity of a cis-acting double GATA motif for Gata1 gene expression.

GATA1 GATA2

4.11e-06271225535330
Pubmed

PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development.

ADAMTS9 GATA1 GATA2 ADAMTS5

6.67e-065971438374152
Pubmed

GATA suppresses erythropoietin gene expression through GATA site in mouse erythropoietin gene promoter.

GATA1 GATA2

1.23e-05371212041667
Pubmed

Cloning and structural analysis of the murine GCN5L1 gene.

RDH16 RDH5

1.23e-0537129426003
Pubmed

GATA transcription factors are involved in IgE-dependent mast cell degranulation by enhancing the expression of phospholipase C-γ1.

GATA1 GATA2

1.23e-05371222390417
Pubmed

Molecular cloning and characterization of the GATA1 cofactor human FOG1 and assessment of its binding to GATA1 proteins carrying D218 substitutions.

GATA1 GATA2

1.23e-05371212483298
Pubmed

An intron GATA-binding site regulates chromatin accessibility and is essential for IL-4 gene expression in mast cells.

GATA1 GATA2

1.23e-05371215739164
Pubmed

Antagonism of FOG-1 and GATA factors in fate choice for the mast cell lineage.

GATA1 GATA2

1.23e-05371218299398
Pubmed

Chromatin occupancy and epigenetic analysis reveal new insights into the function of the GATA1 N terminus in erythropoiesis.

GATA1 GATA2

1.23e-05371231409672
Pubmed

Molecular hallmarks of endogenous chromatin complexes containing master regulators of hematopoiesis.

GATA1 GATA2

1.23e-05371218779319
Pubmed

GATA transcription factors inhibit cytokine-dependent growth and survival of a hematopoietic cell line through the inhibition of STAT3 activity.

GATA1 GATA2

1.23e-05371215673499
Pubmed

GATA factors are essential for transcription of the survival gene E4bp4 and the viability response of interleukin-3 in Ba/F3 hematopoietic cells.

GATA1 GATA2

1.23e-05371212023274
Pubmed

The upregulation of Gata transcription factors family and FOG-1 in expanded and differentiated cord blood-derived CD34+ hematopoietic stem cells to megakaryocyte lineage during co-culture with cord blood mesenchymal stem cells.

GATA1 GATA2

1.23e-05371235690555
Pubmed

Exchange of GATA factors mediates transitions in looped chromatin organization at a developmentally regulated gene locus.

GATA1 GATA2

1.23e-05371218243117
Pubmed

Dynamic regulation of Gata factor levels is more important than their identity.

GATA1 GATA2

1.23e-05371217327407
Pubmed

GATA-1, -2 and -3 genes expression in bone marrow microenviroment with chronic aplastic anemia.

GATA1 GATA2

1.23e-05371217654061
Pubmed

Evaluation of the role of the retinal G protein-coupled receptor (RGR) in the vertebrate retina in vivo.

RDH5 RGR

1.23e-05371212716426
Pubmed

ADAMTS1, ADAMTS5, ADAMTS9 and aggrecanase-generated proteoglycan fragments are induced following spinal cord injury in mouse.

ADAMTS9 ADAMTS5

1.23e-05371223562508
Pubmed

GATA-1 and GATA-2 binding to 3' enhancer of WT1 gene is essential for its transcription in acute leukemia and solid tumor cell lines.

GATA1 GATA2

1.23e-05371219212333
Pubmed

GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis.

GATA1 GATA2

1.23e-05371212077323
Pubmed

A new Adamts9 conditional mouse allele identifies its non-redundant role in interdigital web regression.

ADAMTS9 ADAMTS5

1.23e-05371224753090
Pubmed

Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2.

GATA1 GATA2

1.23e-05371215215894
Pubmed

Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate.

GATA1 GATA2

1.23e-05371219491391
Pubmed

Regulation of GATA factor expression is distinct between erythroid and mast cell lineages.

GATA1 GATA2

1.23e-05371222988301
Pubmed

Transcription factor GATA1 is dispensable for mast cell differentiation in adult mice.

GATA1 GATA2

2.46e-05471224615013
Pubmed

SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis.

GATA1 GATA2

2.46e-05471220457756
Pubmed

Clinical significance of Gata-1, Gata-2, EKLF, and c-MPL expression in acute myeloid leukemia.

GATA1 GATA2

2.46e-05471219097174
Pubmed

Biosynthesis and expression of a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats-15: a novel versican-cleaving proteoglycanase.

ADAMTS9 ADAMTS5

2.46e-05471224220035
Pubmed

Notch1-mediated signaling induces MHC class II expression through activation of class II transactivator promoter III in mast cells.

GATA1 GATA2

2.46e-05471221321116
Pubmed

Histone modifications silence the GATA transcription factor genes in ovarian cancer.

GATA1 GATA2

2.46e-05471216607277
Pubmed

Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18.

ADAMTS9 ADAMTS5

2.46e-05471216507336
Pubmed

Critical Roles for PU.1, GATA1, and GATA2 in the expression of human FcεRI on mast cells: PU.1 and GATA1 transactivate FCER1A, and GATA2 transactivates FCER1A and MS4A2.

GATA1 GATA2

2.46e-05471224639354
Pubmed

An intricate regulatory circuit between FLI1 and GATA1/GATA2/LDB1/ERG dictates erythroid vs. megakaryocytic differentiation.

GATA1 GATA2

4.09e-05571238695236
Pubmed

GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene.

GATA1 GATA2

4.09e-0557121744088
Pubmed

Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1.

GATA1 GATA2

4.09e-0557127568177
Pubmed

Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development.

GATA1 GATA2

4.09e-05571217962413
Pubmed

Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction.

MUS81 FANCA

4.09e-05571226980189
Pubmed

Mast cell IL-4 expression is regulated by Ikaros and influences encephalitogenic Th1 responses in EAE.

GATA1 GATA2

4.09e-05571216628252
Pubmed

Regulation of aggrecanases from the ADAMTS family and aggrecan neoepitope formation during in vitro chondrogenesis of human mesenchymal stem cells.

ADAMTS9 ADAMTS5

4.09e-05571222562232
Pubmed

ADAMTS9 is a cell-autonomously acting, anti-angiogenic metalloprotease expressed by microvascular endothelial cells.

ADAMTS9 CSPG4

4.09e-05571220093484
Pubmed

The C-terminal region of cis-retinol/androgen dehydrogenase 1 (CRAD1) confers ER localization and in vivo enzymatic function.

RDH16 RDH5

4.09e-05571216223484
Pubmed

Normal reproductive and macrophage function in Pem homeobox gene-deficient mice.

GATA1 GATA2

4.09e-0557129769172
Pubmed

Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators.

GATA1 GATA2

6.13e-05671221571218
Pubmed

Gfi-1B promoter remains associated with active chromatin marks throughout erythroid differentiation of human primary progenitor cells.

GATA1 GATA2

6.13e-05671219522008
Pubmed

Initiation of murine embryonic erythropoiesis: a spatial analysis.

GATA1 GATA2

6.13e-0567129028937
Pubmed

Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells.

GATA1 GATA2

6.13e-05671210364157
Pubmed

Abundant expression of transcription factor GATA-2 in proliferating but not in differentiated mast cells in tissues of mice: demonstration by in situ hybridization.

GATA1 GATA2

6.13e-0567128562971
Pubmed

Direct protein interactions are responsible for Ikaros-GATA and Ikaros-Cdk9 cooperativeness in hematopoietic cells.

GATA1 GATA2

6.13e-05671223732910
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SHROOM3 CAMKK1 SEC16A NADK LMTK2 CEP131 PTPN21 CEP170B EIF4E2

6.32e-0586171936931259
Pubmed

Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors.

GATA1 GATA2

8.57e-05771211724781
Pubmed

The expression and regulation of ADAMTS-1, -4, -5, -9, and -15, and TIMP-3 by TGFbeta1 in prostate cells: relevance to the accumulation of versican.

ADAMTS9 ADAMTS5

8.57e-05771215599946
Pubmed

GATA factors and androgen receptor collaborate to transcriptionally activate the Rhox5 homeobox gene in Sertoli cells.

GATA1 GATA2

8.57e-05771218212046
Pubmed

Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults.

ADAMTS9 ADAMTS5

8.57e-05771223354118
Pubmed

Sox7-sustained expression alters the balance between proliferation and differentiation of hematopoietic progenitors at the onset of blood specification.

GATA1 GATA2

1.14e-04871219801444
Pubmed

Gata6 restricts Isl1 to the posterior of nascent hindlimb buds through Isl1 cis-regulatory modules.

GATA1 GATA2

1.14e-04871229197504
Pubmed

Etv2/ER71 induces vascular mesoderm from Flk1+PDGFRα+ primitive mesoderm.

GATA1 GATA2

1.14e-04871221911838
Pubmed

Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation.

ADAMTS9 ADAMTS5

1.14e-04871221041365
Pubmed

The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.

SHROOM3 SEC16A LMTK2 CEP131

1.28e-0412571429467281
Pubmed

Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.

GATA1 GATA2

1.47e-0497127926723
Pubmed

Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongation.

GATA1 GATA2

1.47e-04971221245044
Pubmed

Quantitative axial profiles of retinoic acid in the embryonic mouse spinal cord: 9-cis retinoic acid only detected after all-trans-retinoic acid levels are super-elevated experimentally.

RDH16 RDH5

1.47e-04971211747070
Pubmed

Mouse embryonic head as a site for hematopoietic stem cell development.

GATA1 GATA2

1.47e-04971223122290
Pubmed

Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene.

GATA1 GATA2

1.47e-0497127624372
Pubmed

Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.

PKD1L1 PKD1

1.83e-041071216805797
Pubmed

ADAMTS: a novel family of extracellular matrix proteases.

ADAMTS9 ADAMTS5

1.83e-041071211167130
Pubmed

Neurodegeneration with Brain Iron Accumulation Disorders Overview

DCAF17 PLA2G6

1.83e-041071223447832
Pubmed

Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression.

GATA1 GATA2

1.83e-041071215889140
Pubmed

Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.

ABR PSMB4 MUS81 BIRC6

1.93e-0413971425476789
Pubmed

mTORC1 activity is essential for erythropoiesis and B cell lineage commitment.

GATA1 GATA2

2.23e-041171231729420
Pubmed

Genetic Analysis Reveals a Hierarchy of Interactions between Polycystin-Encoding Genes and Genes Controlling Cilia Function during Left-Right Determination.

PKD1L1 PKD1

2.23e-041171227272319
Pubmed

Immune-related zinc finger gene ZFAT is an essential transcriptional regulator for hematopoietic differentiation in blood islands.

GATA1 GATA2

2.23e-041171220660741
Pubmed

Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor.

GATA1 GATA2

2.23e-04117128799165
Pubmed

Cell signaling directing the formation and function of hemogenic endothelium during murine embryogenesis.

GATA1 GATA2

2.68e-041271218684862
Pubmed

Expression of genes for alcohol and aldehyde metabolizing enzymes in mouse oocytes and preimplantation embryos.

RDH16 RDH5

2.68e-041271212128098
Pubmed

TAF10 Interacts with the GATA1 Transcription Factor and Controls Mouse Erythropoiesis.

GATA1 GATA2

2.68e-041271225870109
Pubmed

GATA-1 self-association controls erythroid development in vivo.

GATA1 GATA2

2.68e-041271217374603
Pubmed

A critical role for endoglin in the emergence of blood during embryonic development.

GATA1 GATA2

2.68e-041271222535663
InteractionTOP3B interactions

KANSL3 SHROOM3 B4GALNT4 ABR ZBED4 CSPG4 PKD1 SEC16A GATA2 NADK LMTK2 MUS81 DISP2 PFAS PLA2G6 CEP131 BIRC6 PRRC2A CEP170B FANCA

5.80e-0814706920int:TOP3B
InteractionCNOT2 interactions

KANSL3 DSCR9 PSMB4 SEC16A PRRC2A MTFR1L EIF4E2

2.53e-06178697int:CNOT2
Cytoband2q37.3

NEU4 KLHL30 ESPNL

2.39e-04777132q37.3
CytobandEnsembl 112 genes in cytogenetic band chr2q37

NEU4 KLHL30 ESPNL EIF4E2

4.29e-04226714chr2q37
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

GATA1 GATA2

5.43e-041542282
GeneFamilyShort chain dehydrogenase/reductase superfamily

RDH16 HSD17B6 RDH5

7.28e-0476423743
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS9 ADAMTS5

8.79e-041942250
CoexpressionAtlasgudmap_RNAseq_e15.5_Mesangium_2500_K3

COL12A1 PIEZO2 FADS3 CAMKK1 CSPG4 ADAMTS5 KLHDC8B

1.51e-05246697gudmap_RNAseq_e15.5_Mesangium_2500_K3
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

NEU4 CSPG4 RDH5 HEPACAM2

1.15e-05877148ca87e4a332ef6f035b13e80dcc0110f32172c9a
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P3|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

NEU4 CSPG4 RDH5 HEPACAM2

1.15e-05877144ec3a9489981ed69061c1ca363271edf6a3635d2
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SHROOM3 COL12A1 FADS3 LMTK2 PTPN21

1.32e-0519071530b50d183d7649146eb1e79b47ba897355f1998a
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FADS3 CSPG4 RDH5 LEMD1 KLHDC8B

1.46e-0519471552ecec2618c3bb5fdd7fb06b5a40bd6f0aedfe1d
ToppCellmedial-2-Epithelial-Alveolar_Epithelial_Type_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SHROOM3 COL12A1 FADS3 HSD17B6 PRSS22

1.65e-05199715456460c761e26ed4b1d88d9bee4d2a7c9bd9d416
ToppCellmedial-Epithelial-Alveolar_Epithelial_Type_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SHROOM3 COL12A1 FADS3 HSD17B6 PRSS22

1.65e-051997155263338242f95c04690d0795749ccc20b0d19f7a
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FADS3 ADAMTS9 KLHL30 CSPG4 RGR

1.65e-051997158ff0fdcbe9661b013913731ec8b53d84836ca865
ToppCellmedial-Epithelial-Alveolar_Epithelial_Type_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SHROOM3 COL12A1 FADS3 HSD17B6 PRSS22

1.65e-05199715c11365653c69a5dfb37946231f8af05149a61a71
ToppCellBiopsy_Other_PF-Epithelial-AT1|Biopsy_Other_PF / Sample group, Lineage and Cell type

SHROOM3 COL12A1 FADS3 HSD17B6 LMTK2

1.69e-05200715b746dcc94814bcbca63c71e6451a9c5f084bcfaf
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Astrocyte|GW09 / Sample Type, Dataset, Time_group, and Cell type.

SLC41A1 RGR CDON FANCA

7.84e-0514271485e573616e54d41391b4ad8c3d38e4ca92112673
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-basophil|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PIEZO2 MAMDC2 GATA2 VWDE

9.69e-05150714408b7c2c3a42f5455c8c26a83d9e366a1c8d5ecc
ToppCellfacs-Marrow-Granulocytes-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAMDC2 GATA2 PLA2G6 PTPN21

1.10e-04155714cd2f3ad4f131588325a667b6724e530d821fbe30
ToppCellfacs-Marrow-Granulocytes-3m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAMDC2 GATA2 PLA2G6 PTPN21

1.10e-041557149b26ade19488511c72b64335011d2dcd81e8f167
ToppCellfacs-Marrow-Granulocytes-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAMDC2 GATA2 PLA2G6 PTPN21

1.10e-041557144246709e27703b94529369abbed5763e4002e79d
ToppCellPND07-28-samps-Mesenchymal-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

HLA-DMB PHYHIP LCT CDON

1.13e-04156714574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCellPND07-28-samps-Mesenchymal-Mesothelial-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

HLA-DMB PHYHIP LCT CDON

1.13e-04156714605d95a900e1443d3f6aae163ef2e893d3293203
ToppCell21-Trachea-Epithelial-Submucosal_gland_basal|Trachea / Age, Tissue, Lineage and Cell class

COL12A1 ADAMTS9 MAMDC2 CSPG4

1.21e-041597144f670b57b8d3b090ea2f1aafe15baf93cb7ef146
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DMB GATA1 GATA2 PHYHIP

1.24e-041607149f24ee4fe1ba4590dce5dd4d43707fb007dca82f
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DMB GATA1 GATA2 PHYHIP

1.24e-041607143b3b99305558f5b49d050fb9b249007630ea9085
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue-6|TCGA-Colorectal / Sample_Type by Project: Shred V9

GBA3 MAMDC2 DISP2 PLCD1

1.30e-041627147f9385aa749bfb2fa9fee6939fe46d946bc21d31
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B4GALNT4 CCNP PRSS22 HEPACAM2

1.30e-04162714ded08da888d8c481f0f96d1e0bfd03d617966910
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Undetermined|Myeloid_cells / Location, Cell class and cell subclass

KLHL30 GATA1 GATA2 PLA2G6

1.34e-04163714be774c0ba38fa89a9c0076524cf05d593c6c6826
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKD1 GATA1 GATA2 HEPACAM2

1.43e-0416671413027ae342994db4540e64eb910df1f42b160931
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKD1 GATA1 GATA2 HEPACAM2

1.43e-04166714b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_Erythro-Mega|bone_marrow / Manually curated celltypes from each tissue

PIEZO2 ADAMTS9 GATA1 GATA2

1.43e-04166714a853005a5587d42daecdf2e23a93109919021a4f
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DMB MAMDC2 CSPG4 CPZ

1.47e-04167714e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCellfacs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSD17B6 CSPG4 PHYHIP VWDE

1.47e-0416771478909f685ccd1321064eb0887caf9263e0e54879
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B4GALNT4 CCNP PRSS22 HEPACAM2

1.53e-0416971405e12524d68d409fed386ffad233305683b4575b
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

ABR MAMDC2 ADAMTS5 MAP3K4

1.53e-0416971484b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SHROOM3 COL12A1 FADS3 PTPN21

1.53e-04169714cd16e8462ee09877be962fbd9a3badcb825820b0
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TDRD5 PIEZO2 RDH5 ADAMTS5

1.64e-04172714073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCell11.5-Distal-Mesenchymal-Mesenchyme_SERPINF1-high|Distal / Age, Tissue, Lineage and Cell class

COL12A1 PHYHIP CPZ ADAMTS5

1.68e-041737146989c9cebcd81eccceac7e5a86152676ee959386
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FADS3 ADAMTS9 CSPG4 PLCD1

1.68e-041737142415b6ff49f334da570577d4e93484d024a3dbd5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FADS3 ADAMTS9 CSPG4 PLCD1

1.68e-041737142acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PHYHIP CPZ ADAMTS5 CDON

1.72e-04174714a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL12A1 FADS3 ADAMTS9 KLHL30

1.72e-04174714015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAMDC2 CSPG4 CPZ HEPACAM2

1.75e-0417571459249c9e83952d7277010e7be3c779e26399eb5d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 CSPG4 CEP131

1.75e-0417571412f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAMDC2 CSPG4 CPZ HEPACAM2

1.75e-04175714b35cc1357495f2a03a6500f807c6e6f8c877734d
ToppCellEndothelial-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

PIEZO2 ADAMTS9 GATA2 ADAMTS5

1.79e-04176714b288116a4588a1f9db9d49af92cea118937c9201
ToppCellAT1_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

TDRD5 COL12A1 FADS3 PTPN21

1.79e-04176714458720776b0151cd55acc352d509599cb62f0ca8
ToppCellfacs-Heart-LA-24m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B4GALNT4 HLA-DMB HEPACAM2 RGR

1.83e-04177714a3f8c26d54e44688bbd678ac7ef55d8ad172617d
ToppCellfacs-Heart-RV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FADS3 CSPG4 RDH5 CEP170B

1.83e-041777147c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCellBAL-Severe-cDC_3|Severe / Compartment, Disease Groups and Clusters

CAMKK1 HLA-DMB GATA2 DISP2

1.83e-04177714939487a05311b66edfc3f44a7955fbf25266d6bf
ToppCellfacs-Heart-RV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FADS3 CSPG4 RDH5 CEP170B

1.83e-04177714e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Tuft|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B4GALNT4 CCNP PRSS22 HEPACAM2

1.87e-04178714f17c3b7bb562ac24c6a03fe3c9ba94c2b434c141
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 ADAMTS9 PTPN21 VWDE

1.87e-041787148f31b3fac51591f7f2bcb898c07708b3e9f93a16
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FADS3 ADAMTS9 CSPG4 PLCD1

1.87e-041787147467e5ab2fcb39cc4a2c7dd69722c91def3b6aea
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SHROOM3 COL12A1 FADS3 LMTK2

1.91e-04179714d5e3e7f1cd8f683f39a7416f12af7e766dcbead8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

B4GALNT4 COL12A1 HSD17B6 LCT

1.95e-04180714ea7a1ccf0dd3bb5af5df87501f873e7339a824b3
ToppCell368C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ABR CEP131 CDON FANCA

1.95e-04180714eb5a57604c7f2ad256c300085dbf5069d0ae1ad0
ToppCell368C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ABR CEP131 CDON FANCA

1.95e-04180714ddba4dc3bbcfe4e4a22400be73bbc62d3ff27d3c
ToppCellfacs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAOX FADS3 CAMKK1 PLA2G6

1.95e-041807147368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCelldroplet-Kidney-nan-18m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL30 MAMDC2 CSPG4 ADAMTS5

1.95e-04180714b6f44fdedc33b7d93b0074e8e9c8cc32009d4c4d
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CAMKK1 ZBED4 GATA2 MUS81

1.99e-04181714338c7362d258a87f1a6b1a65376f5394d4b2b4b2
ToppCell18-Distal-Immune-Hematopoietic,_B_Cells|Distal / Age, Tissue, Lineage and Cell class

TCL1B HLA-DMB DSCR9 GATA1

2.04e-04182714cd0b9f0a25147ec3bc1e32d698511d1c3b33891f
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GATA1 GATA2 CEP131 VWDE

2.04e-041827144cd5eb13f78f4f377932c50ac2acb4ac0cd14c12
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 FADS3 HSD17B6 PTPN21

2.12e-04184714ca940a4f4970285ed284d5517d142abab0682044
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

SHROOM3 COL12A1 FADS3 PTPN21

2.12e-04184714561592edc3083fad41b91811151b442207c65dd9
ToppCelltumor_Lung-Fibroblasts-Mesothelial_cells|tumor_Lung / Location, Cell class and cell subclass

PIEZO2 ADAMTS9 HSD17B6 CDON

2.12e-04184714b0a251030d127858e68cf164be158f209a4d720f
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TDRD5 PIEZO2 RDH5 ADAMTS5

2.12e-041847141c857126c0ea0671f0d60b048efca288d348d653
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 CSPG4 ADAMTS5

2.17e-041857147092436b4db90289516ed130ade596e3021cffaf
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

SHROOM3 COL12A1 FADS3 PTPN21

2.17e-041857141c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 MAMDC2 DISP2 CDON

2.17e-04185714f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 CSPG4 ADAMTS5

2.17e-04185714a8ca7819066d5297ef6966e7f3e2c9f8a7673fdc
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 MAMDC2 DISP2 CDON

2.17e-0418571440e958511790e84321da5ccf735f9974c06a0263
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 MAMDC2 DISP2 CDON

2.17e-041857145f2eeba80aff145e85cfd81e2890a155406badb9
ToppCellMesenchymal_cells-Osteo-CAR|World / Lineage and Cell class

SHROOM3 COL12A1 ADAMTS9 ADAMTS5

2.17e-0418571416f1588893d09c864e0cb4f837a1b972a1a57baa
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MAMDC2 CPZ ADAMTS5 CDON

2.21e-04186714c0a036096c2cb23305605b8aaf18869d6e0fb512
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SHROOM3 FADS3 SOCS5 PLA2G6

2.21e-0418671477bebf576eb9b96ecb4fefb8a82a31aaaa917fc0
ToppCellsystemic_lupus_erythematosus-flare-Hematopoietic-progenitor_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PIEZO2 MAMDC2 GATA2 VWDE

2.21e-04186714ffd4510b4435d9bf94c2ef14c629f73ab78c5d93
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

SHROOM3 COL12A1 LMTK2 PTPN21

2.21e-0418671409d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SHROOM3 FADS3 SOCS5 PLA2G6

2.21e-0418671413bc41c60fd628af31899a5e8b480e06cc4781be
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 CSPG4 ADAMTS5

2.26e-04187714d591a3c216997663ab77710fed0d230ffc37e41a
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 CSPG4 ADAMTS5

2.26e-04187714d1dc8c9a2c2cd10c640257161a75e7730ec5bb41
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FADS3 MAMDC2 CSPG4 RDH5

2.26e-04187714dba4924d914a7dcd4901142684ba920c2404860b
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FADS3 MAMDC2 CSPG4 RDH5

2.26e-041877149688141beef4f62613d7a810c5872ccb9afc1a71
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 CSPG4 ADAMTS5

2.26e-04187714ac8e092b37e042975e2ee057d3f7c6821e58e8b5
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SHROOM3 COL12A1 FADS3 PTPN21

2.26e-04187714d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|368C / Donor, Lineage, Cell class and subclass (all cells)

SHROOM3 HSD17B6 PLA2G6 CEP170B

2.26e-04187714b827d9da7032bf051756ddf88352af922eb0f87b
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|368C / Donor, Lineage, Cell class and subclass (all cells)

SHROOM3 HSD17B6 PLA2G6 CEP170B

2.26e-0418771461c00604dda8b36a5c3eea6554e5601aa1b884f7
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

SHROOM3 COL12A1 FADS3 PTPN21

2.26e-0418771477f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellsystemic_lupus_erythematosus-flare-Hematopoietic-progenitor_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PIEZO2 MAMDC2 GATA2 VWDE

2.31e-04188714c613c6c7b6de8ed514253c9f9b8622c56fcc1452
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-chondrocyte|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

B4GALNT4 ADAMTS9 CSPG4 PTPN21

2.31e-04188714c9270517e6940e9793586f67f02431210552f278
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

SHROOM3 COL12A1 FADS3 PTPN21

2.35e-041897145a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAMDC2 CSPG4 ADAMTS5 KLHDC8B

2.45e-041917148597a8af294f24496c317d995f07eb5dcc25c13c
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABR MAMDC2 CSPG4 RDH5

2.45e-041917145c1f5b6c115b1b27b4a7467a6550ce43c01cf6d0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 CSPG4 ADAMTS5

2.45e-041917147b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PIEZO2 CSPG4 ADAMTS5

2.45e-04191714cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FADS3 CSPG4 RDH5 LEMD1

2.50e-0419271488472b99970ba0decbf87164fc241a1c77b3b389
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAMDC2 CSPG4 ADAMTS5 KLHDC8B

2.50e-041927143617d2bc7e33d981f3ec349e9962d8d4bd822fbd
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABR MAMDC2 CSPG4 RDH5

2.50e-04192714eb9a0b3d32f90f8b95905c740aab21639dae5cbd
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

COL12A1 CSPG4 ADAMTS5 KLHDC8B

2.50e-041927145000440dc1ed17e7474d340921bdff945646f27e
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

COL12A1 MAMDC2 ADAMTS5 CDON

2.55e-04193714cd45118ced91b10baed3b1068d4673ec99824b86
ToppCellILEUM-inflamed-(8)_Smooth_muscle_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

COL12A1 MAMDC2 HSD17B6 ADAMTS5

2.55e-04193714084c88f08ce0ecd6c9f4334caed370eb2154f896
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FADS3 KLHL30 MAMDC2 CSPG4

2.60e-04194714bf34737ae2dc218f890fbb9201c308b324415749
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAMDC2 CSPG4 ADAMTS5 KLHDC8B

2.60e-0419471480be44e9ddd9f6ddd9dff7cba0eb457431204c2d
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FADS3 KLHL30 MAMDC2 CSPG4

2.60e-04194714b35e33439b6d3b5d69147e617224d2c8fd056223
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FADS3 KLHL30 MAMDC2 CSPG4

2.60e-041947144ebed7a6731b88c8359860072cbeba355a7e90ac
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 PIEZO2 MAMDC2 ADAMTS5

2.65e-04195714f54bc4454270ff06e85596f98199372b50d0179f
DiseaseAbnormality of refraction

ADAMTS9 PKD1L1 RDH5 RPUSD2 PLA2G6 CPZ BIRC6 RGR

1.91e-04673708HP_0000539
DiseaseNeurodegeneration with brain iron accumulation

DCAF17 PLA2G6

4.25e-0413702cv:C2931845
DiseaseConnective Tissue Diseases

PIEZO2 PKD1

4.25e-0413702C0009782
DiseaseMYELODYSPLASTIC SYNDROME

GATA1 GATA2 FANCA

5.49e-0467703C3463824
DiseaseSitus ambiguus

SHROOM3 PKD1L1

5.71e-0415702C0266642
Diseaseuric acid measurement

GBA3 SHROOM3 LMTK2 SLC41A1 MTX1 BIRC6 FANCA

6.06e-04610707EFO_0004761
Diseasedepressive disorder (is_implicated_in)

GATA1 GATA2

7.37e-0417702DOID:1596 (is_implicated_in)
Diseaseovulation

PRRC2A FANCA

9.24e-0419702GO_0030728
Diseasemyelodysplastic syndrome (is_marker_for)

GATA1 GATA2

1.03e-0320702DOID:0050908 (is_marker_for)
Diseasealpha-linolenic acid measurement

FADS3 LCT

1.61e-0325702EFO_0007759
DiseaseHematopoetic Myelodysplasia

GATA1 GATA2

2.16e-0329702C2713368

Protein segments in the cluster

PeptideGeneStartEntry
ARLATSRSLLHWYPS

TDRD5

961

Q8NAT2
HRGLPRLSWIDTLYS

ABR

6

Q12979
WTTHSRSPIAYERGR

DCAF17

51

Q5H9S7
TPPHRRARSAAWSYI

BIRC6

3186

Q9NR09
GRVLYLHSRPEAWSD

CSPG4

1316

Q6UVK1
SAPWRHRSHCFYRGT

ADAMTS5

121

Q9UNA0
WFLVSSSGARHRLPR

CEP170B

6

Q9Y4F5
HRSFRDLPSWSFLRS

CCNP

286

Q9H8S5
KRYTSGHWSLTRPGV

DNAI3

716

Q8IWG1
DVWLRRPSTHTSGYS

DISP2

1386

A7MBM2
HSYSPRAIHSWLTRA

PSMB4

126

P28070
YDTVRDTWTRHGALP

KLHL30

536

Q0D2K2
RWAARAPSTRITYGT

LEMD1

116

Q68G75
SSWHRRRGETPTSYT

MAMDC2

526

Q7Z304
ASTRDRWLHKPSYTR

FAM166C

86

A6NJV1
LSHWRRSAYTPALKT

ESPNL

746

Q6ZVH7
SDLPTWRRGTGYTLS

MAGEC3

141

Q8TD91
WRRGTGYTLSLPAVS

MAGEC3

146

Q8TD91
YATGPASHISPRAWR

CAMKK1

91

Q8N5S9
RPGVYISLSAHRSWV

PRSS22

271

Q9GZN4
TWSYNHPIRGRAKSR

NADK

31

O95544
PSYWHPSRRIQGSLR

MDM1

636

Q8TC05
HYRFSISWSRILPDG

LCT

1446

P09848
RSTEQSWPHSAPYSR

LMTK2

1456

Q8IWU2
YARVRSDTRPLRHTW

MTFR1L

76

Q9H019
TWLLYSHPVGRRARL

NEU4

376

Q8WWR8
KSFRYWPRLGSRHNT

PTPN21

1006

Q16825
WPRLGSRHNTVTYGR

PTPN21

1011

Q16825
HLSRIYPAGWRTDSS

PLCD1

546

P51178
TISPGYSIHTYLWRR

GBA

521

P04062
VAATSSLLRRWPYGS

RGR

71

P47804
ATPLWRRDRTGHYLC

GATA1

211

P15976
TATPLWRRDGTGHYL

GATA2

301

P23769
RSTYSAPRTQWRFGS

ADAMTS9

1176

Q9P2N4
GVISWRRAGHSSYTP

HLA-DMB

236

P28068
ALTSVHPRTRYSAGW

HSD17B6

271

O14756
SYFTSLSTHRPRWLL

CPZ

636

Q66K79
RTHRSFRVSWTPPSD

COL12A1

1396

Q99715
RAPPSWSRDHAYSRR

DSCR9

81

P59020
LTHYRFSLSWSRLLP

GBA3

71

Q9H227
TWKATGSRSYSPDHR

ELOA

141

Q14241
WSFARTHPLLTSLYR

FANCA

346

O15360
DIAPGSNWRRLYSHL

CDON

261

Q4KMG0
TTRHLAARYGLPAAW

IGFLR1

281

Q9H665
PSSSVFPTSRRHRFW

KANSL3

281

Q9P2N6
TWTRHPSLPSRRAFA

KLHDC8B

201

Q8IXV7
SADSHPPNTYSWIRR

HEPACAM2

271

A8MVW5
TFWYSRRTPGRPTSS

EIF4E2

61

O60573
YDISRWAQRHPGGSR

FADS3

46

Q9Y5Q0
RPRTHHRGRYAWASE

CEP131

476

Q9UPN4
FHVWLSVYSRPSSSR

PKD1L1

1936

Q8TDX9
AATSPSPRRVAYHWD

PKD1

2081

P98161
SVLRSRWHSAPYTRG

PAOX

421

Q6QHF9
RAGPTALSRYVGHLW

MTX1

66

Q13505
AYPRGDSSGSTRRSW

MAP3K4

1261

Q9Y6R4
VLGHWRYDLRRPSFT

RPUSD2

11

Q8IZ73
TRLARRDSYSRHAPW

SOCS5

106

O75159
ALIACHPRTRYSAGW

RDH16

271

O75452
WNRLHTATSRKSYRP

PRRC2A

1611

P48634
SYAAFRHRERPSSWS

SHROOM3

391

Q8TF72
ARRSPATREVLYSGW

SLC41A1

306

Q8IVJ1
TVRGHWFLSPRTEYS

PHYHIP

71

Q92561
WRAARSSGAAPTYFR

PLA2G6

631

O60733
ALTARHPRTRYSPGW

RDH5

271

Q92781
GTPRHSRALSWAARA

B4GALNT4

486

Q76KP1
LRSPYRSVRFDSWHL

VWDE

31

Q8N2E2
FRRGSYLTVHWRTHT

ZNF624

761

Q9P2J8
RTTYRRRNPGSWSLT

ZNF324

71

O75467
PRSVFWASSPYRRRA

SEC16A

21

O15027
HNLSGRYESRWASVR

PFAS

1196

O15067
TAGRRRSLWYATHYP

PIEZO2

381

Q9H5I5
PSRREWARASQGSRY

TCL1B

41

O95988
TSGSRRRSAVWKHFY

ZBED4

281

O75132
YARRLGGAWARRSHS

LRFN4

596

Q6PJG9
RLYQGHTLRSRPWGT

MUS81

421

Q96NY9