Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	cell cycle process	FOXM1 BAZ1B DACT1 SYCP2 E2F8 SPTBN1 ANAPC2 TUBGCP3 POC1B CEP135 BTN2A3P	1.19e-05	1441	34	11	GO:0022402
GeneOntologyCellularComponent	centriole	NEURL4 TUBGCP3 POC1B CEP135	2.12e-04	172	36	4	GO:0005814
Domain	Prefoldin	DACT1 CEP135	8.95e-03	72	37	2	IPR009053
Domain	-	FOXM1 E2F8 ANAPC2	9.10e-03	218	37	3	1.10.10.10
Domain	WHTH_DNA-bd_dom	FOXM1 E2F8 ANAPC2	1.21e-02	242	37	3	IPR011991
Pubmed	Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation.	FOXM1 E2F8	2.30e-05	7	37	2	31130414
Pubmed	CEP295 interacts with microtubules and is required for centriole elongation.	POC1B CEP135	3.07e-05	8	37	2	27185865
Pubmed	Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum.	VLDLR GOLGB1	4.93e-05	10	37	2	20809939
Pubmed	Evolutionary plasticity of segmentation clock networks.	DACT1 E2F8	9.94e-05	14	37	2	21652651
Pubmed	CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion.	POC1B CEP135	9.94e-05	14	37	2	32060285
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CNDP2 BAZ1B BBS2 NEURL4 GOLGB1 SPTBN1 TUBGCP3 NCBP3	1.40e-04	1487	37	8	33957083
Pubmed	Mice without macroH2A histone variants.	PIP5K1B VLDLR	1.86e-04	19	37	2	25312643
Pubmed	Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method.	GOLGB1 SPTBN1	2.51e-04	22	37	2	18487259
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	SLC9A3 POMT1 NAT9 GOLGB1 SPTBN1 TUBGCP3 NCBP3	3.74e-04	1293	37	7	15342556
Pubmed	The c-Ski family member and transcriptional regulator Corl2/Skor2 promotes early differentiation of cerebellar Purkinje cells.	VLDLR GOLGB1	4.09e-04	28	37	2	24491816
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	TUBGCP3 POC1B CEP135	5.07e-04	146	37	3	21399614
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	FOXM1 PRKD1 PSKH2 ANAPC2	6.44e-04	372	37	4	22939624
Pubmed	Dissociation of heterotrimeric g proteins in cells.	HTR5A CHRM2 CCR9	9.16e-04	179	37	3	18577758
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PRKD1 SPTBN1	2.57e-02	206	22	2	682
Drug	BS-6181	PRKD1 CHRM2	7.70e-06	3	37	2	CID003082101
Drug	alpha-methyl-5-HT	PRKD1 HTR5A CHRM2	1.12e-05	27	37	3	CID000002107
Drug	mianserin	ADCY10 PRKD1 HTR5A CHRM2	1.19e-05	87	37	4	CID000004184
Drug	Ticlopidine hydrochloride [53885-35-1]; Up 200; 13.4uM; HL60; HG-U133A	DIP2C NAT9 E2F8 SPTBN1 TUBGCP3	1.64e-05	198	37	5	1975_UP
Drug	AC1NUW4G	FOXM1 HTR5A CHRM2	3.74e-05	40	37	3	CID005462134
Drug	NSC186061	ADCY10 PRKD1 HTR5A CHRM2	3.97e-05	118	37	4	CID000004163
Drug	33 d	PRKD1 CHRM2	5.37e-05	7	37	2	CID000012233
Drug	L-689,660	PRKD1 CHRM2	5.37e-05	7	37	2	CID000132658
Disease	Primary microcephaly	TUBGCP3 CEP135	3.11e-04	22	35	2	C0431350
Disease	C-reactive protein measurement, high density lipoprotein cholesterol measurement	BAZ1B PCIF1	7.49e-04	34	35	2	EFO_0004458, EFO_0004612
Disease	depressive symptom measurement, response to antidepressant	DIP2C GOLGB1	4.91e-03	88	35	2	EFO_0007006, GO_0036276
Disease	lipid measurement, intermediate density lipoprotein measurement	BAZ1B PCIF1	5.81e-03	96	35	2	EFO_0004529, EFO_0008595

Protein segments in the cluster

Peptide	Gene	Start	Entry
TLEMHKRKYWALTSL	BTN2A3P	391	Q96KV6
YEQLKAMRTLSWKHT	ANAPC2	626	Q9UJX6
YELLEHKKRWASMSE	BAZ1B	526	Q9UIG0
RYTSRKMHDFKWARD	FAM47DP	221	A6NHR8
YWHISRASKSRIKKD	CHRM2	206	P08172
TAYELWLKDQRKAMH	ADCY10	936	Q96PN6
EGWMVHYTSKDTLRK	PRKD1	426	Q15139
YSHKSRHMWSKRNLR	PSKH2	361	Q96QS6
TKYRNLEMLWKFHSS	JHY	536	Q6NUN7
SIAIRSWHAEKKMYN	GLIPR1L2	131	Q4G1C9
ILQSYRLMKKLEHSW	PIP5K1B	351	O14986
MKGILSNSWKRRYHS	NCBP3	291	Q53F19
TDRLWHDKYTLRKSM	TUBGCP3	456	Q96CW5
SEDKSIKVWSMYRQR	POC1B	121	Q8TC44
WRMLALRSDDSEHKY	POMT1	551	Q9Y6A1
MKSRVHKYITEVSRW	CEP135	851	Q66GS9
NKSMTFDHRLTRKIW	GABRR3	126	A8MPY1
KTSRYWRIKSKNHAM	BBS2	231	Q9BXC9
HKRTDYRRWKSSAEI	DACT1	671	Q9NYF0
SWLRKDHSASKEDYM	PCIF1	321	Q9H4Z3
SLHMVSRLAKNRYTW	E2F8	166	A0AVK6
AMRAHTWREKRLLYS	CCR9	151	P51686
WTRSMKVAYSILHKL	DIP2C	356	Q9Y2E4
WSITRHMEYTLRTRK	HTR5A	141	P47898
STERKRMTLKDIYTW	FOXM1	251	Q08050
RLEAGTLTKKWHMAY	NEURL4	1406	Q96JN8
NVTWKIKLRSAMYHS	TAS2R30	161	P59541
KWSHFDRKFLSRVLM	SLC9A3	506	P48764
MSYDEARNLHSKWLK	SPTBN1	1301	Q01082
KKDILMHRWRYPSLS	CNDP2	301	Q96KP4
DMERWIKEHREYSTK	VPS50	916	Q96JG6
TSHWEKTMSRRYKKV	TBC1D10C	71	Q8IV04
IRHKMLSYFTTQSWK	SYCP2	1376	Q9BX26
HMSGWSYKRVEKSDL	PPM1M	301	Q96MI6
LEAWQKELYKHVMRS	ZNF786	26	Q8N393
KSRLYWLDSKLHMLS	VLDLR	611	P98155
KSSWEIHERRMKEQY	GOLGB1	2956	Q14789
SRYHEWMKSEELQRL	NAT9	26	Q9BTE0