Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessaxon extension

TRIM46 ISLR2 WDR36 MAP1B SEMA5B L1CAM PLXNA4

2.09e-06135907GO:0048675
GeneOntologyBiologicalProcessregulation of axon extension

TRIM46 ISLR2 WDR36 MAP1B L1CAM PLXNA4

6.28e-06104906GO:0030516
GeneOntologyBiologicalProcessdevelopmental growth involved in morphogenesis

TRIM46 MAGI2 ISLR2 WDR36 MAP1B SEMA5B L1CAM PLXNA4 LZTS2

6.33e-06299909GO:0060560
GeneOntologyBiologicalProcessregulation of extent of cell growth

TRIM46 ISLR2 WDR36 MAP1B L1CAM PLXNA4

1.57e-05122906GO:0061387
GeneOntologyBiologicalProcessregulation of cellular component size

TRIM46 PTK2B ISLR2 WDR36 MAP1B L1CAM PLXNA4 TRIOBP PREX1 BAIAP2L2

1.67e-054269010GO:0032535
GeneOntologyBiologicalProcessneuron projection extension

TRIM46 ISLR2 WDR36 MAP1B SEMA5B L1CAM PLXNA4

3.42e-05207907GO:1990138
GeneOntologyBiologicalProcessneuron projection development

TRIM46 MAGI2 PTK2B ISLR2 ABI3 WDR36 MAP1B SEMA5B L1CAM PLXNA4 LAMA3 TRIOBP LGR6 HERC1 MAP2K2 PREX1 NCDN

3.53e-0512859017GO:0031175
GeneOntologyBiologicalProcessnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

BCL2L12 TAF9B TAF9

4.32e-0516903GO:1902166
GeneOntologyBiologicalProcesspostsynapse assembly

MAGI2 PTK2B ABI3 MAP1B ARHGEF15

5.43e-0593905GO:0099068
GeneOntologyBiologicalProcessregulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

BCL2L12 TAF9B TAF9

8.68e-0520903GO:1902165
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

TRIM46 ISLR2 ABI3 WDR36 MAP1B SEMA5B L1CAM PLXNA4 LAMA3 TRIOBP LGR6 MAP2K2

9.71e-057489012GO:0048667
GeneOntologyBiologicalProcesspositive regulation of axonogenesis

ISLR2 MAP1B L1CAM PLXNA4 MAP2K2

1.43e-04114905GO:0050772
GeneOntologyBiologicalProcessmitochondrion localization

MAP1B NECTIN2 CLUH MSTO1

1.66e-0463904GO:0051646
GeneOntologyBiologicalProcessneuron development

TRIM46 MAGI2 PTK2B ISLR2 ABI3 WDR36 MAP1B SEMA5B L1CAM PLXNA4 LAMA3 TRIOBP LGR6 HERC1 MAP2K2 PREX1 NCDN

1.74e-0414639017GO:0048666
GeneOntologyBiologicalProcessaxonogenesis

TRIM46 ISLR2 WDR36 MAP1B SEMA5B L1CAM PLXNA4 LAMA3 LGR6 MAP2K2

1.79e-045669010GO:0007409
GeneOntologyBiologicalProcesscell morphogenesis

TRIM46 PTK2B ISLR2 ABI3 LATS2 WDR36 MAP1B SEMA5B L1CAM PLXNA4 PKHD1 LAMA3 TRIOBP LGR6 MAP2K2

1.92e-0411949015GO:0000902
GeneOntologyBiologicalProcessregulation of axonogenesis

TRIM46 ISLR2 MAP1B L1CAM PLXNA4 MAP2K2

1.96e-04192906GO:0050770
GeneOntologyBiologicalProcessnegative regulation of intrinsic apoptotic signaling pathway by p53 class mediator

BCL2L12 TAF9B TAF9

2.43e-0428903GO:1902254
GeneOntologyBiologicalProcessregulation of neuron projection development

TRIM46 MAGI2 PTK2B ISLR2 ABI3 MAP1B L1CAM PLXNA4 MAP2K2 PREX1

3.33e-046129010GO:0010975
GeneOntologyBiologicalProcessdevelopmental cell growth

TRIM46 ISLR2 WDR36 MAP1B SEMA5B L1CAM PLXNA4

3.49e-04301907GO:0048588
GeneOntologyBiologicalProcessregulation of anatomical structure size

TRIM46 PTK2B ISLR2 WDR36 MAP1B L1CAM PLXNA4 TRIOBP PREX1 BAIAP2L2

3.60e-046189010GO:0090066
GeneOntologyBiologicalProcessnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

BCL2L12 TAF9B TAF9

3.64e-0432903GO:1902230
GeneOntologyBiologicalProcesscell growth

TRIM46 PTK2B ISLR2 WDR36 TAF9B MAP1B SEMA5B L1CAM PLXNA4 WFDC1

3.93e-046259010GO:0016049
GeneOntologyBiologicalProcessregulation of cell growth

TRIM46 PTK2B ISLR2 WDR36 TAF9B MAP1B L1CAM PLXNA4 WFDC1

4.37e-04519909GO:0001558
GeneOntologyBiologicalProcessregulation of cell size

TRIM46 ISLR2 WDR36 MAP1B L1CAM PLXNA4

4.58e-04225906GO:0008361
GeneOntologyBiologicalProcessaxon development

TRIM46 ISLR2 WDR36 MAP1B SEMA5B L1CAM PLXNA4 LAMA3 LGR6 MAP2K2

4.85e-046429010GO:0061564
GeneOntologyBiologicalProcesspositive regulation of cell-substrate adhesion

PTK2B L1CAM TRIOBP PREX1 EPHA1

4.94e-04149905GO:0010811
GeneOntologyBiologicalProcessregulation of protein polymerization

PTK2B MAP1B TRIOBP PREX1 BAIAP2L2 PINK1

5.26e-04231906GO:0032271
GeneOntologyBiologicalProcesspeptidyl-serine autophosphorylation

MAP2K2 PINK1

6.64e-049902GO:0036289
GeneOntologyBiologicalProcessregulation of cell adhesion

MAGI1 MAGI2 PTK2B L1CAM BRD7 PLXNA4 PKHD1 CD55 LAMA3 TRIOBP PREX1 EPHA1

6.86e-049279012GO:0030155
DomainTFIID-31

TAF9B TAF9

6.72e-053892IPR003162
DomainTFIID-31kDa

TAF9B TAF9

6.72e-053892PF02291
DomainPDZ

MAGI1 MAGI2 ARHGAP23 PREX1 PDZRN4

7.10e-04148895SM00228
Domain-

MAGI1 MAGI2 ARHGAP23 PREX1 PDZRN4

7.54e-041508952.30.42.10
DomainPDZ

MAGI1 MAGI2 ARHGAP23 PREX1 PDZRN4

7.77e-04151895PS50106
DomainPDZ

MAGI1 MAGI2 ARHGAP23 PREX1 PDZRN4

8.01e-04152895IPR001478
DomainWW

MAGI1 MAGI2 ARHGAP27

1.46e-0347893PF00397
DomainWW

MAGI1 MAGI2 ARHGAP27

1.55e-0348893SM00456
DomainPROTEIN_KINASE_ATP

BLK PTK2B LATS2 GRK5 MAP2K2 EPHA1 PINK1 SBK2

1.55e-03459898PS00107
DomainWW_DOMAIN_2

MAGI1 MAGI2 ARHGAP27

1.85e-0351893PS50020
DomainWW_DOMAIN_1

MAGI1 MAGI2 ARHGAP27

1.85e-0351893PS01159
DomainWW_dom

MAGI1 MAGI2 ARHGAP27

1.95e-0352893IPR001202
DomainPLAC

ADAMTS19 ADAMTS17

1.97e-0314892PF08686
DomainProtein_kinase_ATP_BS

BLK PTK2B LATS2 GRK5 MAP2K2 EPHA1 SBK2

2.22e-03379897IPR017441
DomainProt_kinase_dom

BLK PTK2B LATS2 GRK5 MAP2K2 EPHA1 PINK1 SBK2

2.31e-03489898IPR000719
DomainPROTEIN_KINASE_DOM

BLK PTK2B LATS2 GRK5 MAP2K2 EPHA1 PINK1 SBK2

2.42e-03493898PS50011
DomainGuanylate_kinase_CS

MAGI1 MAGI2

2.58e-0316892IPR020590
DomainTSP_1

ADAMTS19 SEMA5B ADAMTS17

3.38e-0363893PF00090
DomainPLAC

ADAMTS19 ADAMTS17

3.64e-0319892PS50900
DomainPLAC

ADAMTS19 ADAMTS17

3.64e-0319892IPR010909
DomainTSP1

ADAMTS19 SEMA5B ADAMTS17

3.69e-0365893SM00209
DomainTSP1_rpt

ADAMTS19 SEMA5B ADAMTS17

3.69e-0365893IPR000884
DomainTSP1

ADAMTS19 SEMA5B ADAMTS17

3.69e-0365893PS50092
DomainPH_dom-like

PTK2B MTMR12 ARHGAP23 TRIOBP ARHGAP27 PREX1 ARHGEF15

4.23e-03426897IPR011993
DomainKinase-like_dom

BLK PTK2B LATS2 GRK5 MAP2K2 EPHA1 PINK1 SBK2

4.31e-03542898IPR011009
DomainPDZ

MAGI1 MAGI2 ARHGAP23 PDZRN4

4.63e-03141894PF00595
DomainADAM_spacer1

ADAMTS19 ADAMTS17

5.32e-0323892IPR010294
DomainGUANYLATE_KINASE_2

MAGI1 MAGI2

5.32e-0323892PS50052
DomainGUANYLATE_KINASE_1

MAGI1 MAGI2

5.32e-0323892PS00856
DomainADAM_spacer1

ADAMTS19 ADAMTS17

5.32e-0323892PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS19 ADAMTS17

5.79e-0324892IPR013273
DomainGuanylate_kin

MAGI1 MAGI2

6.77e-0326892PF00625
DomainGK/Ca_channel_bsu

MAGI1 MAGI2

6.77e-0326892IPR008145
DomainGuanylate_kin-like_dom

MAGI1 MAGI2

6.77e-0326892IPR008144
DomainGuKc

MAGI1 MAGI2

6.77e-0326892SM00072
DomainMetalloPept_cat_dom

ADAMTS19 ADAMTS17 PAPPA

6.83e-0381893IPR024079
Domain-

ADAMTS19 ADAMTS17 PAPPA

6.83e-03818933.40.390.10
DomainIPT

PLXNA4 PKHD1

7.29e-0327892SM00429
DomainACR

ADAMTS19 ADAMTS17

7.29e-0327892SM00608
DomainADAM_Cys-rich

ADAMTS19 ADAMTS17

7.29e-0327892IPR006586
DomainTyrKc

BLK PTK2B EPHA1

8.57e-0388893SM00219
DomainTyr_kinase_cat_dom

BLK PTK2B EPHA1

8.57e-0388893IPR020635
DomainRho_GTPase_activation_prot

ARHGAP23 PLXNA4 ARHGAP27

8.57e-0388893IPR008936
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

BLK PTK2B BCL2L12 LATS2 AP2A2 KCNH2 GRK5 TUT7 PELI3 MAP2K2 SEC23B

3.72e-06730921134857952
Pubmed

TMEPAI family: involvement in regulation of multiple signalling pathways.

PMEPA1 LDLRAD4

6.92e-06292229945215
Pubmed

Co-expression of activin receptor-interacting protein 1 and 2 in mouse nerve cells.

MAGI1 MAGI2

6.92e-06292223523645
Pubmed

In vivo functional analysis of the histone 3-like TAF9 and a TAF9-related factor, TAF9L.

TAF9B TAF9

6.92e-06292212837753
Pubmed

MAGI1 copy number variation in bipolar affective disorder and schizophrenia.

MAGI1 MAGI2

6.92e-06292222381734
Pubmed

Mitochondrial Raf1 Regulates Glutamine Catabolism.

TRAF3IP2 LATS2 MRPL37 ARHGAP27 MAP2K2 DDC MSTO1

1.19e-0528892738496616
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

SEMA5B L1CAM NECTIN2 PLXNA4 EPHA1

1.54e-0511792517145500
Pubmed

EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells.

ARHGEF15 EPHA1

2.07e-05392212775584
Pubmed

Human TAFII31 protein is a transcriptional coactivator of the p53 protein.

TAF9B TAF9

2.07e-0539227761466
Pubmed

Essential Role of Linx/Islr2 in the Development of the Forebrain Anterior Commissure.

ISLR2 L1CAM

2.07e-05392229739947
Pubmed

Localization and functional consequences of a direct interaction between TRIOBP-1 and hERG proteins in the heart.

KCNH2 TRIOBP

2.07e-05392229507111
Pubmed

MAP1B is required for Netrin 1 signaling in neuronal migration and axonal guidance.

MAP1B L1CAM

4.14e-05492215186740
Pubmed

C18 ORF1, a novel negative regulator of transforming growth factor-β signaling.

PMEPA1 LDLRAD4

4.14e-05492224627487
Pubmed

SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes.

MAP1B PINK1

4.14e-05492231277379
Pubmed

Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.

MAGI1 MAGI2 PDZRN4

1.01e-043492330726710
Pubmed

Delta proteins and MAGI proteins: an interaction of Notch ligands with intracellular scaffolding molecules and its significance for zebrafish development.

MAGI1 MAGI2

1.03e-04692215509766
Pubmed

Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1.

PREX1 NCDN

1.03e-04692226792863
Pubmed

Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins.

MAGI1 MAGI2

1.03e-0469229647693
Pubmed

No association between EGR gene family polymorphisms and schizophrenia in the Chinese population.

EGR4 KCNH2

1.03e-04692220144677
Pubmed

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.

C1orf198 WIZ AP2A2 MAP1B DHX37 MRPL37 TUT7 ARL15

1.04e-0454792837267103
Pubmed

Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.

MAGI1 MAGI2 PDZRN4

1.20e-043692326053890
Pubmed

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.

PTK2B AP2A2 EPHA1

1.30e-043792324162737
Pubmed

Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.

ADAMTS19 ADAMTS17

1.44e-04792211867212
Pubmed

Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.

L1CAM PLXNA4

1.44e-04792219063725
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

LATS2 WIZ KCNH2 GRK5 L1CAM HELZ2 CHSY1 GRIN2D HERC1 FAAP100 PREX1

1.63e-041105921135748872
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ISLR2 ARHGAP23 SEMA5B DHX37

1.66e-0410392410819331
Pubmed

FAK-MAPK-dependent adhesion disassembly downstream of L1 contributes to semaphorin3A-induced collapse.

L1CAM PLXNA4

1.92e-04892218464795
Pubmed

Proteomic analysis of beta1-adrenergic receptor interactions with PDZ scaffold proteins.

MAGI1 MAGI2

1.92e-04892216316992
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TRIM46 MAGI1 MAGI2 WIZ AP2A2 BRD7 TRIOBP GRIN2D BCOR NCDN

2.35e-04963921028671696
Pubmed

Activation of cannabinoid type 2 receptors inhibits HIV-1 envelope glycoprotein gp120-induced synapse loss.

GRIN2D CNR2

2.46e-04992221670103
Pubmed

TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9.

TAF9B TAF9

2.46e-04992215899866
Pubmed

The role of neuropilins in cell signalling.

L1CAM PLXNA4

2.46e-04992219909241
Pubmed

Dorsal turning of motor corticospinal axons at the pyramidal decussation requires plexin signaling.

L1CAM PLXNA4

2.46e-04992218727829
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

WIZ AP2A2 MAP1B GPATCH1 BCOR

2.74e-0421592535973513
Pubmed

The Semaphorin receptor PlexinA3 mediates neuronal apoptosis during dorsal root ganglia development.

L1CAM PLXNA4

3.07e-041092219020035
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

TRAF3IP2 MTMR12 MAP1B ARHGAP23 DHX37 TUT7 NCDN SEC23B

3.35e-0465092838777146
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

AP2A2 HELZ2 TRIOBP PREX1 ARHGEF15

3.37e-0422592512168954
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AP2A2 ARHGAP23 KIAA0586 HELZ2 PREX1 ARHGEF15 PDZRN4

3.42e-0449392715368895
Pubmed

DSCAM regulates delamination of neurons in the developing midbrain.

MAGI1 MAGI2

3.75e-041192232917586
Pubmed

Linx mediates interaxonal interactions and formation of the internal capsule.

ISLR2 L1CAM

3.75e-041192224930700
Pubmed

Human immunodeficiency virus tat modulates the Flk-1/KDR receptor, mitogen-activated protein kinases, and components of focal adhesion in Kaposi's sarcoma cells.

PTK2B MAP2K2

4.49e-04129229621077
Pubmed

COUP-TFI is required for the formation of commissural projections in the forebrain by regulating axonal growth.

MAP1B L1CAM

4.49e-041292217021036
Pubmed

BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.

WDR36 WIZ TAF9B TAF9

4.53e-0413492425452129
Pubmed

Role of SAP97 protein in the regulation of corticotropin-releasing factor receptor 1 endocytosis and extracellular signal-regulated kinase 1/2 signaling.

MAGI1 MAGI2

5.30e-041392223576434
Pubmed

Optimising experimental design for high-throughput phenotyping in mice: a case study.

MAGI2 BRD7

5.30e-041392220799038
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MAGI1 NDUFS7 LATS2 MAP1B NECTIN2 LAMA3 TRIOBP LZTS2 ARL15 MAP2K2 TMEM255B NCDN

5.55e-041489921228611215
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

NDUFS7 WDR36 WIZ BRD7 HELZ2 PCDHB7 CD55 TRIOBP LZTS2 TAF9 BCOR PREX1

5.82e-041497921231527615
Pubmed

The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila.

MAP1B PINK1

6.17e-041492221151955
Pubmed

Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density.

MAGI1 MAGI2

7.11e-041592223782696
Pubmed

Regulation of the Mdm2-p53 pathway by the ubiquitin E3 ligase MARCH7.

TRIM46 LZTS2

7.11e-041592229295817
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ISLR2 NDUFS7 WIZ TAF9B ARHGAP23 BRD7 LZTS2 TAF9 BCOR ENKD1

7.42e-041116921031753913
Pubmed

Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.

PTK2B MAP1B ARHGAP23

7.59e-046792329254152
Pubmed

Antagonistic functions of Dishevelleds regulate Frizzled3 endocytosis via filopodia tips in Wnt-mediated growth cone guidance.

AP2A2 L1CAM

8.11e-041692224305805
Pubmed

Balance between BDNF and Semaphorins gates the innervation of the mammary gland.

SEMA5B PLXNA4

8.11e-041692230628891
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

PTK2B AP2A2 CHSY1 GRIN2D NCDN

9.21e-0428192528706196
Pubmed

Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.

TAF9B TAF9

1.03e-031892229111974
Pubmed

Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.

ADAMTS19 ADAMTS17

1.03e-031892235503090
Pubmed

Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex.

MAP1B L1CAM

1.03e-031892222090513
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS19 SEMA5B ADAMTS17

1.05e-037592320637190
Pubmed

Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.

WIZ EGR4

1.15e-031992230385546
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

ISLR2 SEMA5B PLXNA4 CHSY1 LGR6 ENKD1 ARID5A BAIAP2L2 TMEM139

1.20e-0398592912975309
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

MAGI1 MTMR12 LATS2 AP2A2 LZTS2 MAP2K2

1.21e-0344692624255178
Pubmed

Cytoplasmic ATXN7L3B Interferes with Nuclear Functions of the SAGA Deubiquitinase Module.

TAF9B TAF9

1.27e-032092227601583
Pubmed

Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4.

TAF9B TAF9

1.27e-032092217884155
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

TRIM46 ADAMTS19 ARHGAP23 GRK5 TUT7 KIAA0586 NECTIN2 LZTS2 FAAP100 EPHA1

1.41e-031215921015146197
Pubmed

The protein tyrosine kinase family of the human genome.

BLK PTK2B EPHA1

1.41e-038392311114734
Pubmed

Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners.

ABI3 MAP1B TAF9 MSTO1

1.53e-0318692431540324
Pubmed

Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation.

L1CAM MAP2K2

1.54e-032292225926459
Pubmed

Proteomic analysis of NMDA receptor-adhesion protein signaling complexes.

PTK2B GRIN2D MAP2K2

1.56e-038692310862698
Pubmed

Proximity labeling reveals dynamic changes in the SQSTM1 protein network.

NDUFS7 C1orf198 MAP1B LZTS2 SEC23B

1.68e-0332292539098523
Pubmed

Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions.

L1CAM EPHA1

1.69e-032392225480914
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

WDR36 MAP1B DHX37 TUT7 HELZ2 CLUH SEC23B

1.76e-0365392722586326
Pubmed

MEK Is a Key Regulator of Gliogenesis in the Developing Brain.

L1CAM MAP2K2

1.84e-032492222998872
Pubmed

Cellular localization and characterization of cytosolic binding partners for Gla domain-containing proteins PRRG4 and PRRG2.

MAGI1 MAGI2

2.00e-032592223873930
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MAGI1 PTK2B MTMR12 MAP1B NECTIN2 MAP2K2 ENKD1 SEC23B

2.04e-0386192836931259
Pubmed

Ca2+ homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling.

L1CAM EPHA1

2.16e-032692235927240
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

LAMA3 CNR2

2.16e-032692224742657
Pubmed

Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice.

CHSY1 PAPPA

2.16e-032692233905568
Pubmed

Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death.

MAP1B L1CAM

2.16e-032692217875933
Pubmed

Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.

TAF9B TROAP LZTS2

2.48e-0310192326949739
Pubmed

Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.

SEMA5B PLXNA4

2.50e-032892218617019
Pubmed

Alternatively spliced isoforms of WT1 control podocyte-specific gene expression.

MAGI2 CD55

2.50e-032892225993318
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

MTMR12 TUT7 HELZ2

2.55e-0310292311214970
GeneFamilyPDZ domain containing

MAGI1 MAGI2 ARHGAP23 PREX1 PDZRN4

1.48e-041526051220
GeneFamilyBeta 4-glycosyltransferases

CHSY1 B4GALT3

1.43e-0317602425
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS19 ADAMTS17

1.79e-031960250
GeneFamilyCalcium voltage-gated channel subunits|Membrane associated guanylate kinases

MAGI1 MAGI2

3.34e-0326602904
GeneFamilyPRD class homeoboxes and pseudogenes

ALX3 RAX NOBOX

3.54e-0392603521
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA

TRIM46 MAGI2 PTK2B MAP1B ARHGAP23 L1CAM PLXNA4 PAPPA DDC NCDN PDZRN4

1.47e-065069111M39067
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

MAP1B SEMA5B KCNH2 GRK5 L1CAM WFDC1 LGR6 PDZRN4

2.99e-09172938c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ISLR2 ABI3 ARHGAP27 CCDC141 TMEM255B PREX1 ARHGEF15

1.91e-07197937a7922f65a8af4a773e4ce80114e4d895a594fa2f
ToppCell11.5-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

MAP1B KCNH2 PLXNA4 WFDC1 LGR6 PMEPA1 LDLRAD4

2.05e-071999371a8c77d241bd817a195e1532fd25f51358cb1ff1
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

SEMA5B KCNH2 GRK5 L1CAM LGR6 PDZRN4

1.01e-061589368d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

ISLR2 MAP1B PLXNA4 WFDC1 LGR6 PDZRN4

1.71e-06173936a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 C1orf198 MAP1B KCNH2 PAPPA CCDC141

2.15e-06180936d67d3196e6cc3dcd31023a4dc69310226181d583
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 C1orf198 MAP1B KCNH2 PAPPA CCDC141

2.15e-06180936573308d43425d9fba20787abdb7f8efefc48efb5
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MAGI1 KCNH2 PLXNA4 WFDC1 PMEPA1 LDLRAD4

2.69e-06187936387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI2 MAP1B PLXNA4 PAPPA LGR6 LDLRAD4

2.86e-0618993645e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellHealthy_donor-B_intermediate|World / disease group, cell group and cell class (v2)

BLK DENND5B ADAMTS19 CCDC141 PMEPA1 CNR2

3.13e-06192936f77007b284e11f8654ad599eef929df7c6c4ebf0
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MAGI1 SEMA5B PLXNA4 WFDC1 LGR6 PMEPA1

3.22e-06193936000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ISLR2 ARHGAP27 CCDC141 TMEM255B PREX1 ARHGEF15

3.22e-0619393601c71aa48875b5ad6c50cc810a72862e72f26ad0
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

MAGI1 MAP1B ARHGAP23 NECTIN2 CD55 ARHGEF15

3.42e-061959366b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCell11.5-Distal-Mesenchymal-Airway_Smooth_Muscle|Distal / Age, Tissue, Lineage and Cell class

KCNH2 PLXNA4 WFDC1 LGR6 PMEPA1 LDLRAD4

3.52e-0619693605530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ISLR2 ABI3 ARHGAP27 TMEM255B PREX1 ARHGEF15

3.63e-0619793621a1080e1db3a64f3eccc7aed2b3189332d31038
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

C1orf198 GRK5 CD55 LAMA3 PMEPA1 TMEM139

3.63e-0619793669d5b8588046d119b5dff9a7fd6f49e97e00a5b7
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

C1orf198 GRK5 CD55 LAMA3 PMEPA1 TMEM139

3.63e-06197936e6cbfa267eb2e05b441fd034786faae07bb0e081
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

WIZ AP2A2 EGR4 MRPL37 PELI3 GRIN2D

3.96e-06200936f11ae9055e72c938b6c9e52701478b2eee681ac4
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

MAP1B LAMA3 WFDC1 LGR6 PDZRN4

2.22e-0516193547b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellfacs-Marrow-KLS-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXNA4 ADAMTS17 LZTS2 BCOR ARHGEF15

2.65e-051679352812353ff66e76f10bd327ceb0e6b009502a5258
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1B PELI3 PCDHB7 PAPPA PMEPA1

2.65e-05167935805129f887078340b260aa136b0ba19f2bd6ea03
ToppCellfacs-Marrow-KLS-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXNA4 ADAMTS17 LZTS2 BCOR ARHGEF15

2.65e-05167935d15168f46c1599d9fc68a05a7b822c4b439f2987
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1B PELI3 PCDHB7 PAPPA PMEPA1

2.65e-0516793531cf8bf2eb523f6e7e319620648ff37fc09e2601
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1B PELI3 PCDHB7 PAPPA PMEPA1

2.65e-051679353acb18428d1d33ad430c2fd031b1a91baee3c01d
ToppCell10x5'-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue

DENND5B ARHGAP23 PLXNA4 PMEPA1 LDLRAD4

2.73e-0516893590f713dae3fcbd6ca801a019e3861c263ff3366b
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8|TCGA-Thryoid / Sample_Type by Project: Shred V9

PTK2B MTMR12 ARHGAP23 NCDN PDZRN4

2.73e-0516893500646601548b0fee42ae16bfa5e93603bc7c5129
ToppCellAT1-AT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

MAGI1 C1orf198 LAMA3 CCDC141 TMEM139

2.80e-05169935815474855a70498a74e52f6583113c63b7267a0c
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ISLR2 SEMA5B PAPPA LGR6 PDZRN4

2.97e-051719354ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCellNS-moderate-d_16-33-Lymphoid-B_cell|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BLK DENND5B CCDC141 LDLRAD4 CNR2

3.50e-05177935320fd77c7c98e9305dcc34a168ec9d674539ed65
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEMA5B WFDC1 LGR6 TMEM255B PDZRN4

3.69e-05179935f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCellNS-moderate-d_16-33-Myeloid-pDC|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BLK DENND5B PLXNA4 PMEPA1 LDLRAD4

3.79e-05180935144818e69613296cde43f29cb8c20899c670b319
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAGI1 ABI3 TMEM255B PREX1 ARHGEF15

3.79e-0518093597e0dcb7cfbba60a782824c5e23995058609fcd4
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAD2 ISLR2 ARL15 TMEM255B ARHGEF15

3.99e-051829350346f81bbb1f309f3e9d063b20547d548d09472c
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTK2B ISLR2 MAP1B ANKEF1 L1CAM

3.99e-05182935be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BLK DENND5B CCDC141 PMEPA1 CNR2

4.10e-05183935ffa831f67ed005f05d1b80ebc707e046fc08e22f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEMA5B WFDC1 LGR6 TMEM255B PDZRN4

4.10e-0518393565f2a5895d166189a095cf7ea9dda171f0419b08
ToppCellMild-Lymphoid-B|Mild / Condition, Lineage, Cell class and cell subclass

BLK DENND5B EGR4 CCDC141 CNR2

4.10e-051839359b64d2d143525e6f48a191facfd101462ff36324
ToppCellMild_COVID-19-B_cell|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

BLK DENND5B EGR4 CCDC141 CNR2

4.10e-05183935dea119e2988e954475f557f0bbe12556a83e81a4
ToppCellMild-Lymphoid-B-|Mild / Condition, Lineage, Cell class and cell subclass

BLK DENND5B EGR4 CCDC141 CNR2

4.10e-05183935b5740f05a4dcdbbf24f7bf7a3f57ac01a5e75f60
ToppCellCV-Severe-3|CV / Virus stimulation, Condition and Cluster

ISLR2 SDR42E2 L1CAM PMEPA1 LDLRAD4

4.21e-051849351c9bda00bb6efd98f68781ca06655bf6c4282f27
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

BLK DENND5B EGR4 CCDC141 CNR2

4.21e-051849353f8a359e40bebe58545f708682e5e5d1b70cf5cb
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

BLK DENND5B EGR4 CCDC141 CNR2

4.21e-0518493564bede8db709fd32f40c03265b96f0b12155bb8a
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 C1orf198 GRK5 CD55 LAMA3

4.32e-051859351c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MAP1B PLXNA4 LGR6 CCDC141 DDC

4.32e-05185935427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCellBAL-Mild-Lymphocyte-B-B_cell|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

BLK DENND5B EGR4 CCDC141 CNR2

4.32e-05185935609080adb2cfb105bb7b8efb617553833299f371
ToppCelldroplet-Thymus-nan-24m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLK DENND5B CD55 GM2A CNR2

4.32e-05185935a92bd84e44fc992b7eeefaa2ff8091ed09f0df00
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI2 KCNH2 PLXNA4 PAPPA WFDC1

4.32e-051859353b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCelldroplet-Thymus-nan-24m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLK DENND5B CD55 GM2A CNR2

4.32e-05185935877eb127ac797f8a1e1a9e0049fa16cae16cfa35
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI2 MAP1B WFDC1 LGR6 LDLRAD4

4.43e-051869356add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNH2 LGR6 CCDC141 SBK2 PDZRN4

4.43e-05186935337f768cc43db2db96ba6495b076006b1a5b0331
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNH2 LGR6 CCDC141 SBK2 PDZRN4

4.43e-05186935e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCellmoderate-Lymphoid-B_cell|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

BLK DENND5B CCDC141 LDLRAD4 CNR2

4.43e-05186935fd2c4c3e8929ca5d64f6c5064e5f3d3d6ba07b5f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAP1B SEMA5B WFDC1 LGR6 PDZRN4

4.43e-051869354780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellMild_COVID-19-B_cell-B_cell|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

BLK DENND5B EGR4 CCDC141 CNR2

4.43e-05186935855a5a00ba2aa1b5c63b8db56d026ddecc546050
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAP1B SEMA5B WFDC1 LGR6 PDZRN4

4.43e-05186935a95744b8649096bd7cfc3591a02841fa411085b3
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ALX3 C1orf198 SEMA5B LAMA3 ARID5A

4.54e-05187935b8f88599e22b9b345c7ec3bbecd87a8b2a033f9f
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

MAGI2 MAP1B PLXNA4 WFDC1 PDZRN4

4.54e-05187935464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B GRK5 WFDC1 PMEPA1 PDZRN4

4.54e-05187935ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 C1orf198 GRK5 CD55 LAMA3

4.54e-05187935d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B GRK5 WFDC1 PMEPA1 PDZRN4

4.54e-05187935530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B GRK5 WFDC1 LGR6 PDZRN4

4.66e-05188935b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

C1orf198 CD55 LAMA3 PMEPA1 TMEM139

4.66e-05188935e9cef856a96a97afac5ecafe2ee91eff0d731e01
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KCNH2 PLXNA4 WFDC1 LGR6 PMEPA1

4.66e-05188935c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PLXNA4 WFDC1 LGR6 PMEPA1 LDLRAD4

4.66e-051889354d1e5f85342ae550086609d7680e32730b78b5d2
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KCNH2 PLXNA4 WFDC1 LGR6 PMEPA1

4.66e-05188935f54b063025d80de631382bf5326bc40aab7f7d00
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH2 PLXNA4 WFDC1 PMEPA1 LDLRAD4

4.66e-051889353004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCellSmart-seq2-spleen_(Smart-seq2)|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

BLK DENND5B ABI3 CD55 ARID5A

4.78e-05189935b0244a9d1b5c8ad4708750b691184f3491b13900
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAP1B SEMA5B WFDC1 LGR6 PDZRN4

4.78e-05189935975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNH2 LGR6 CCDC141 SBK2 PDZRN4

4.78e-05189935e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCellfacs-Spleen-nan-18m-Lymphocytic-CD79a_B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLK DENND5B ABI3 CD55 GM2A

4.78e-05189935159769abb867595f0d20a1835b715b3a96d0a38d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B GRK5 WFDC1 LGR6 PDZRN4

4.78e-05189935127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH2 PLXNA4 WFDC1 LGR6 PMEPA1

4.78e-05189935da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B GRK5 WFDC1 LGR6 PDZRN4

4.78e-051899352cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNH2 LGR6 CCDC141 SBK2 PDZRN4

4.78e-05189935b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MAGI1 PLXNA4 WFDC1 PMEPA1 LDLRAD4

4.78e-051899350abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

C1orf198 MAP1B KCNH2 ARID5A PDZRN4

4.90e-051909352e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellMesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

PLXNA4 WFDC1 LGR6 PMEPA1 LDLRAD4

4.90e-05190935645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCellCOVID-19-lung-Artery_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAGI1 GRK5 ARL15 TMEM255B ARID5A

4.90e-0519093507b675befcd1d0a9c90cb17b5d22323468325d51
ToppCellfacs-Spleen-nan-18m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BLK DENND5B ABI3 CD55 GM2A

4.90e-0519093519c645884950fd261218c42be60f00a2437164a3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B KCNH2 WFDC1 ARID5A PDZRN4

4.90e-05190935562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

C1orf198 MAP1B KCNH2 ARID5A PDZRN4

4.90e-051909350028f886c789ba238c031eae5d96acaed4af8c25
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 C1orf198 GRK5 CD55 LAMA3

4.90e-0519093530b50d183d7649146eb1e79b47ba897355f1998a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B GRK5 WFDC1 PMEPA1 PDZRN4

4.90e-051909355681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B KCNH2 WFDC1 ARID5A PDZRN4

4.90e-05190935f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ISLR2 ARHGAP27 TMEM255B PREX1 ARHGEF15

4.90e-051909357ba2be2630183df86de21689289a8620a4cd507e
ToppCellControl-Lymphoid_B-B_intermediate|Control / Disease group, lineage and cell class

BLK DENND5B CCDC141 PMEPA1 CNR2

5.02e-051919350082181dbc39c7c4fd3aa34c3ed61439548e844b
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

C1orf198 GRK5 CD55 LAMA3 TMEM139

5.02e-05191935a15e34ad7dbf3f2f13d5e23ce3ffb6d08fd1f9f0
ToppCellLAM-Epithelial-AT1|Epithelial / Condition, Lineage and Cell class

MAGI1 C1orf198 GRK5 CD55 LAMA3

5.02e-051919353457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BLK DENND5B PLXNA4 PMEPA1 LDLRAD4

5.02e-05191935989bf108c7f2c78dd7f14481570f1819673a5469
ToppCellLAM-Epithelial-AT1|LAM / Condition, Lineage and Cell class

MAGI1 C1orf198 CD55 LAMA3 TMEM139

5.02e-0519193566875b2ec2c510489407f3e433a90cdf74a15094
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI2 MAP1B PLXNA4 WFDC1 LGR6

5.02e-0519193508042952431ca1a6fd7dfc13f36eb28643979598
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B WFDC1 LGR6 LDLRAD4 PDZRN4

5.02e-0519193504c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 PKHD1 CD55 LAMA3 CCDC141

5.02e-05191935ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BLK DENND5B PLXNA4 PMEPA1 LDLRAD4

5.02e-051919353e7fbe4af2c23b3b964becde843d2f088ad41c23
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BLK DENND5B PLXNA4 PMEPA1 LDLRAD4

5.02e-05191935bc2f3c4e71e3a55fe76ea03f45746329a8fc81da
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISLR2 LAMA3 WFDC1 TMEM255B ARHGEF15

5.02e-05191935b9ae5af426e7a1f2652a47700bb168371bd2dec6
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

BLK DENND5B PLXNA4 PMEPA1 LDLRAD4

5.15e-05192935d9ff2293358c8b031ba212021012e058014ff472
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ABI3 ARHGAP27 TMEM255B PREX1 ARHGEF15

5.15e-051929357dbe3117a0f58ff2e838963d49f788a59a4351d7
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

KCNH2 PLXNA4 WFDC1 PMEPA1 LDLRAD4

5.15e-051929357ae3e1ca8bfc078c0e12a1595ecb0e343dab5d2f
ToppCell3'-Child09-12-SmallIntestine-Neuronal-Glial_mature|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1orf198 MAP1B L1CAM PAPPA PMEPA1

5.15e-05192935ac507fd7cf3b3e521a15ef03bb4e81eb23807985
DiseaseMAJOR AFFECTIVE DISORDER 2

MAGI1 MAGI2 DDC

1.69e-0517883C1839839
Diseaseserum gamma-glutamyl transferase measurement

TRIM46 GPATCH1 NECTIN2 PKHD1 TRIOBP LZTS2 ARL15 FAAP100 PMEPA1 ARHGEF15 EPHA1

8.63e-059148811EFO_0004532
Diseasecancer antigen 15.3 measurement

TRIM46 MSTO1

1.83e-047882EFO_0010585
DiseaseAdenoid Cystic Carcinoma

MAGI1 MAGI2 BCOR MAP2K2

2.33e-04100884C0010606
Diseaseglioblastoma (is_marker_for)

L1CAM BRD7 MAP2K2

3.11e-0444883DOID:3068 (is_marker_for)
DiseaseDental enamel hypoplasia

SEMA5B DHX37

5.69e-0412882EFO_1001304
Diseasemagnesium measurement

TRIM46 ADAMTS19 ARL15

1.02e-0366883EFO_0004845
Diseaseprostate cancer (is_marker_for)

PTK2B WFDC1 PMEPA1 PREX1

1.24e-03156884DOID:10283 (is_marker_for)
Diseasediet measurement, HOMA-B

MAGI1 PLXNA4

1.45e-0319882EFO_0004469, EFO_0008111
Diseasebipolar disorder (is_marker_for)

NDUFS7 L1CAM

1.45e-0319882DOID:3312 (is_marker_for)
Diseaseneuroticism measurement

BLK MAGI1 PTK2B PKHD1 ARHGAP27 HERC1 PMEPA1 CLUH SEC23B

1.56e-03909889EFO_0007660
DiseaseAnophthalmia-microphthalmia syndrome

BCOR RAX

1.78e-0321882cv:C5680330
DiseaseNerve Degeneration

GRIN2D DDC PINK1

1.98e-0383883C0027746
DiseaseParkinson Disease

NECTIN2 DDC PINK1

2.12e-0385883C0030567
Diseasecortical surface area measurement

ALX3 MAGI1 ADAMTS19 TUT7 PKHD1 TRIOBP PAPPA ARHGAP27 ARL15 PMEPA1 PDZRN4

2.17e-0313458811EFO_0010736
Diseasecentral corneal thickness

TRAF3IP2 ADAMTS19 ADAMTS17 CHSY1 PMEPA1

2.35e-03309885EFO_0005213
DiseaseAlzheimer disease, high density lipoprotein cholesterol measurement

NECTIN2 EPHA1

2.73e-0326882EFO_0004612, MONDO_0004975
Diseaseserum urea measurement

TRIM46 LGR6 ARL15 MSTO1

2.80e-03195884EFO_0009795

Protein segments in the cluster

PeptideGeneStartEntry
DGYRLPPPVDCPAPL

EPHA1

841

P21709
PQGLPYCPERSPLLV

B4GALT3

71

O60512
CLDSVLGPCLPPPYV

ADAD2

446

Q8NCV1
LGPCLPPPYVRTALH

ADAD2

451

Q8NCV1
CLLGPALGPVPPEAY

ARID5A

486

Q03989
PIPPDPTLCPDNYRR

ENKD1

11

Q9H0I2
PPPARPEYDLVCIGL

ARL15

26

Q9NXU5
CRLGEEPPPLPYCDQ

C19orf48

61

Q6RUI8
PVDPIVGEPGYCPVR

BRD7

356

Q9NPI1
TRPPPNMICLLGPSY

BRD7

566

Q9NPI1
PRLTRFPACGPLEPY

ALX3

46

O95076
SPRPCSLPIRPCYGL

BCL2L12

151

Q9HB09
LPLPICVIPEYAFPR

ANKEF1

431

Q9NU02
TPGPLPCSPDTIYED

ARHGEF15

741

O94989
PDVEPGYLRPLIPAA

DDC

31

P20711
PVCTNGERFLYLPPP

BCOR

236

Q6W2J9
RPLYCPGPRPAAVQS

ADAMTS17

901

Q8TE56
LLRLLQCYPPPDPAV

AP2A2

261

O94973
QCYPPPDPAVRGRLT

AP2A2

266

O94973
PRPCSELFPLIPNDY

CNR2

176

P34972
PVYRLPALPCAPPSV

ISLR2

221

Q6UXK2
SLVELAVGRYPIPPP

MAP2K2

256

P36507
RPRCQPLPCPYGEAL

MSANTD5

106

A0A3B3IT52
CQPLAPGELYRVLPL

PDZRN4

56

Q6ZMN7
QYRICENPPCPAGLP

ADAMTS19

676

Q8TE59
PLAVPEFPVCGLYRI

NOBOX

31

O60393
ITLPPPCSYLEELEP

NOBOX

491

O60393
APENLPPLTPYCRRP

ABI3

126

Q9P2A4
YPCGEFSPRPPETRV

FAM47C

181

Q5HY64
PPGLPVYLDLCYIPN

MAP1B

2351

P46821
GYEAQEPLCPAVPPR

LZTS2

66

Q9BRK4
KYRSPVPLTPPGCVA

MPV17L2

186

Q567V2
PPLPSYGLDLCEFPL

MCMDC2

106

Q4G0Z9
ELCRGYPLPFDPDDP

MAGI1

551

Q96QZ7
LCRGYPLPFDPEDPA

MAGI2

506

Q86UL8
RPYGVPVDAPDGCIP

LAMA3

411

Q16787
LFLPPTTVPPECYRD

NCDN

246

Q9UBB6
PLDVEYGGPDRRCPP

LATS2

501

Q9NRM7
CERLPAYFVVPTPLP

MTMR12

236

Q9C0I1
LCLPYAPPEGQPAAL

LGR6

716

Q9HBX8
DTPLYNLEPCEPLPF

HERC1

2366

Q15751
GRQYQELPRCPAPTP

KCNH2

1006

Q12809
PPYPSGRLTPTCLDM

BAIAP2L2

241

Q6UXY1
PLPECREIYCPAPPQ

CD55

216

P08174
GEKVLPPCYRQEPAP

C1orf198

221

Q9H425
EREEFGPRLPPVFCP

GPATCH1

826

Q9BRR8
TGPDEDNPKCYPPRI

PLXNA4

86

Q9HCM2
PLLPGALVDYPDVLP

PINK1

286

Q9BXM7
PPGELCPDVLYRTGR

MSTO1

41

Q9BUK6
LPCNPPPSAEPLRIY

L1CAM

156

P32004
CPAELPAVPANRLYP

EGR4

351

Q05215
VPPACPEPQGCYLEL

PAPPA

771

Q13219
SEPPPLDRVYEIPGL

MRPL37

41

Q9BZE1
PELREYCLPGPVLCA

FAAP100

336

Q0VG06
EEPPPYQGPCTLQLR

PMEPA1

156

Q969W9
PCTEPLPRAAEPGYL

PCDHB7

571

Q9Y5E2
YGDTTLLREPCPPER

CEFIP

306

Q711Q0
YECVSPDDISLPPLP

CCDC141

1206

Q6ZP82
RPDTCPPELYRGVIA

BLK

456

P51451
YEPVICQRPGPSELP

DENND5B

251

Q6ZUT9
CQRPGPSELPLSDYP

DENND5B

256

Q6ZUT9
RVDRSCPYLTVPGPP

FRMD6-AS1

26

P0C7T7
LRTCVLRPPGIYGPE

SDR42E2

201

A6NKP2
GDRLPKPDLCPPVLY

PTK2B

641

Q14289
NRETLPDPCPVPYGS

HELZ2

1761

Q9BYK8
LDPPFVPDPRAVYCK

GRK5

461

P34947
KPLEEPAPTYCPERG

DHX37

1016

Q8IY37
LAGPPIPYTAPELCA

SBK2

216

P0C263
RLPPGEPCREGYVLS

NIPAL1

6

Q6NVV3
TGEPCPEPLRTYGLP

GM2A

121

P17900
AGPRLPPDRYCLTAP

TAF9B

111

Q9HBM6
SGPRLPPDRYCLTAP

TAF9

111

Q16594
PLPPRLGICLDYERG

TRIM46

686

Q7Z4K8
YPLPLQPCSRFPVAP

TMEM255B

266

Q8WV15
ERECPLCRLVGPYVP

PELI3

381

Q8N2H9
FIPYREGPIPEPCAL

PRR23B

186

Q6ZRT6
APGLPACLYLRPAAP

ARHGAP27

136

Q6ZUM4
PQGAPRLYRLCQPPV

PREX1

1641

Q8TCU6
PLLPPIRTGPYLCEL

WIZ

231

O95785
TDLPPYPDILLRCGS

PKHD1

2656

P08F94
DRIVPVDIYIPGCPP

NDUFS7

171

O75251
AEVPYCDLPRCPPAP

TRIOBP

46

Q9H2D6
LPPVQYEPVLCSRPT

SEC23B

51

Q15437
EAPRPYCPKEPGEAR

RAX

96

Q9Y2V3
EEYVAPPRGPLPTLQ

TRAF3IP2

556

O43734
IPVVPLRGVDDSYPP

CHSY1

131

Q86X52
PIDCTPPEYILPGSR

CLUH

181

O75153
PPEYILPGSRERPLC

CLUH

186

O75153
GCGFPVYPTRILPPR

SHFL

176

Q9NUL5
AYACLEAVPPPPVLD

WFDC1

101

Q9HC57
SGEARSIPEPPPICY

ARHGAP23

176

Q9P227
IPEPPPNSGYECQLR

UBTD2

141

Q8WUN7
EPYPPAEPRPLESCC

TROAP

546

Q12815
SRPCPYSEIPVILPA

SEMA5B

1006

Q9P283
LCSIDRPEEGGLPPY

TUT7

446

Q5VYS8
LEPLTPPPAYDVCFG

TMEM139

186

Q8IV31
YLPARVCTPLPTPQP

KIAA0586

1031

Q9BVV6
IPTIPGLVPRYAAPE

WDR36

791

Q8NI36
PPYQGPCTLQLRDPE

LDLRAD4

181

O15165
CRAAPPPCPYLDLEP

GRIN2D

1096

O15399
ELPCHLLPPVPGLYI

NECTIN2

51

Q92692