Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionactin filament binding

BIN1 HIP1 CAMSAP3 PKNOX2 FRG1 MYO15A MARCKS VCL

2.49e-052271048GO:0051015
GeneOntologyMolecularFunctionbenzoate-CoA ligase activity

ACSM2A ACSM2B

8.03e-0531042GO:0018858
GeneOntologyMolecularFunctiondecanoate-CoA ligase activity

ACSM2A ACSM2B

1.60e-0441042GO:0102391
GeneOntologyMolecularFunctionC-acyltransferase activity

ACAT1 ACSM2A ACSM2B

1.70e-04211043GO:0016408
GeneOntologyMolecularFunctionacid-thiol ligase activity

SUCLG1 ACSM2A ACSM2B

5.55e-04311043GO:0016878
GeneOntologyMolecularFunctionmolecular adaptor activity

BIN1 HIP1 RBM33 PPRC1 ARRDC1 OBSL1 BCOR SKI TAB3 NCOR2 TELO2 HGS TRIM55 AP1G2 AKAP1 SPEN VCL

6.15e-04135610417GO:0060090
GeneOntologyMolecularFunctionspectrin binding

CAMSAP3 CAMSAP1 UNC13A

7.30e-04341043GO:0030507
GeneOntologyMolecularFunctionfatty-acyl-CoA synthase activity

ACSM2A ACSM2B

7.37e-0481042GO:0004321
GeneOntologyCellularComponentneuron projection terminus

BIN1 L1CAM APC GRIN2A SLC1A2 UNC13A MARCKS

1.66e-042331047GO:0044306
GeneOntologyCellularComponentmicrotubule minus-end

CAMSAP3 CAMSAP1

5.07e-0471042GO:0036449
GeneOntologyCellularComponentcatenin complex

APC CDH24 CDH3

5.34e-04321043GO:0016342
GeneOntologyCellularComponentmicrotubule organizing center

CAMSAP3 OBSL1 APC NFS1 SKI CCDC141 SPICE1 RABL6 PKHD1 ZFYVE26 CAMSAP1 KIF17 MARCKS

6.36e-0491910413GO:0005815
GeneOntologyCellularComponentsupramolecular fiber

COL6A3 BIN1 INCENP DYNC2H1 CAMSAP3 OBSL1 APC EVPL FRG1 TRIM55 TTL CAMSAP1 KIF17 MARCKS VCL

7.20e-04117910415GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

COL6A3 BIN1 INCENP DYNC2H1 CAMSAP3 OBSL1 APC EVPL FRG1 TRIM55 TTL CAMSAP1 KIF17 MARCKS VCL

7.72e-04118710415GO:0099081
GeneOntologyCellularComponenttranscription repressor complex

BIN1 SKI NCOR2 SPEN

9.37e-04871044GO:0017053
HumanPhenoAbnormality of the elbow

COL6A3 L1CAM OBSL1 APC BCOR SKI RECQL4 ASPH ALDH18A1 KMT2A CDT1 UNC80

3.64e-062824512HP:0009811
DomainCAMSAP_CC1

CAMSAP3 CAMSAP1

9.00e-0531032PF17095
DomainCAMSAP_CKK

CAMSAP3 CAMSAP1

9.00e-0531032SM01051
DomainPRC_barrel-like

CAMSAP3 CAMSAP1

9.00e-0531032IPR011033
DomainCKK_domain

CAMSAP3 CAMSAP1

9.00e-0531032IPR014797
DomainCAMSAP_CKK

CAMSAP3 CAMSAP1

9.00e-0531032PF08683
DomainCAMSAP_CC1

CAMSAP3 CAMSAP1

9.00e-0531032IPR031372
DomainCAMSAP

CAMSAP3 CAMSAP1

9.00e-0531032IPR032940
DomainCKK

CAMSAP3 CAMSAP1

9.00e-0531032PS51508
DomainCAMSAP_CH

CAMSAP3 CAMSAP1

6.21e-0471032PF11971
DomainCAMSAP_CH

CAMSAP3 CAMSAP1

6.21e-0471032IPR022613
DomainBROMODOMAIN_2

BAZ2B PBRM1 KMT2A

1.49e-03411033PS50014
DomainBromodomain

BAZ2B PBRM1 KMT2A

1.60e-03421033IPR001487
DomainBROMO

BAZ2B PBRM1 KMT2A

1.60e-03421033SM00297
Domain-

BAZ2B PBRM1 KMT2A

1.60e-034210331.20.920.10
DomainCadherin_CS

PCDHAC1 CDH24 PCDH10 CDH3

3.12e-031091034IPR020894
DomainCADHERIN_1

PCDHAC1 CDH24 PCDH10 CDH3

3.55e-031131034PS00232
DomainCadherin

PCDHAC1 CDH24 PCDH10 CDH3

3.55e-031131034PF00028
DomainFN3

COL6A3 L1CAM OBSL1 IGDCC3 SDK1

3.62e-031851035SM00060
DomainCADHERIN_2

PCDHAC1 CDH24 PCDH10 CDH3

3.66e-031141034PS50268
Domain-

PCDHAC1 CDH24 PCDH10 CDH3

3.66e-0311410342.60.40.60
DomainCA

PCDHAC1 CDH24 PCDH10 CDH3

3.78e-031151034SM00112
DomainAMP-bd_C

ACSM2A ACSM2B

3.88e-03171032IPR025110
DomainAMP-binding_C

ACSM2A ACSM2B

3.88e-03171032PF13193
DomainCadherin-like

PCDHAC1 CDH24 PCDH10 CDH3

3.89e-031161034IPR015919
DomainIg_I-set

L1CAM OBSL1 IGDCC3 SIGLEC1 SDK1

4.05e-031901035IPR013098
DomainI-set

L1CAM OBSL1 IGDCC3 SIGLEC1 SDK1

4.05e-031901035PF07679
DomainCadherin

PCDHAC1 CDH24 PCDH10 CDH3

4.14e-031181034IPR002126
DomainFN3

COL6A3 L1CAM OBSL1 IGDCC3 SDK1

4.92e-031991035PS50853
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

BIN1 ILF3 PDHA1 CAMSAP3 FNBP4 BCOR TRIP12 SPICE1 MICALL1 NCOR2 ASPH OSBPL11 KMT2A ANKRD17 CDT1 AKAP1 SPEN

2.83e-107741081715302935
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

EXOSC9 OBSL1 CCDC141 TRIP12 PBRM1 FRG1 KMT2A CRYBG1 BOD1L1 CDT1 EIF2A SPEN TASOR

2.66e-094691081327634302
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ILF3 HYOU1 PDHA1 DYNC2H1 FNBP4 OBSL1 NUDCD3 NFS1 SPICE1 MICALL1 TELO2 TRABD CLPTM1 HGS ASPH EIF2A AKAP1 PPP6R2 ITM2B MARCKS VCL

5.42e-0914871082133957083
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

EXOSC9 HIP1 RBM33 CAMSAP3 APC BCOR PLCD3 PBRM1 FRG1 ASPH ALDH18A1 KMT2A ANKRD17 CRYBG1 EIF2A AKAP1 SPEN ITM2B TASOR MARCKS

3.31e-0814971082031527615
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

ILF3 HYOU1 APC SPICE1 MICALL1 RABL6 HGS ALDH18A1 ANKRD17 BOD1L1 CAMSAP1 EIF2A MARCKS VCL

4.43e-087081081439231216
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HIP1 PPRC1 L1CAM MICALL1 PLCD3 RABL6 NCOR2 ARHGEF40 TKFC KCNH2 KCNK5 AP1G2 ZFYVE26 CAMSAP1 SPEN WNK2 AGTRAP

5.51e-0811051081735748872
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

HYOU1 CAMSAP3 OBSL1 APC PLCD3 ARHGEF40 RECQL4 ASPH OSBPL11 KMT2A ANKRD17 PPP6R2 TASOR

1.22e-076501081338777146
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

BIN1 ILF3 CAMSAP3 APC GRIN2A BCOR SLC1A2 SPICE1 NCOR2 PBRM1 ANKRD17 CAMSAP1 PPP6R2 UNC13A WNK2

3.08e-079631081528671696
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

BIN1 HYOU1 RBM33 APC NUDCD3 CLPTM1 HGS BOD1L1 CDT1 CAMSAP1 AKAP1 TASOR VCL

4.78e-077331081334672954
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ILF3 NUDCD3 BCOR OSBPL11 KMT2A ANKRD17 BOD1L1 CAMSAP1 EIF2A AKAP1 PPP6R2 TASOR MARCKS VCL

1.24e-069341081433916271
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

EXOSC9 ILF3 INCENP ACAT1 RBM33 BAZ2B FNBP4 BCOR TRIP12 NCOR2 KMT2A BOD1L1 SPEN TASOR

1.59e-069541081436373674
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

BIN1 ACAT1 PDHA1 CAMSAP3 APC GRIN2A NFS1 SUCLG1 SLC1A2 TAB3 CAMSAP1 PPP6R2 UNC13A MARCKS WNK2

2.48e-0611391081536417873
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

ILF3 HYOU1 ACAT1 RBM33 APC TRIP12 MICALL1 ANKRD17 CAMSAP1 EIF2A SPEN VCL

2.73e-067241081236232890
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

COL6A3 ACAT1 DYNC2H1 ARRDC1 EVPL DDC TKFC HGS PKHD1 MYO15A SPEN ITM2B MARCKS VCL

3.30e-0610161081419056867
Pubmed

The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.

ACAT1 PDHA1 NFS1 SUCLG1 ALDH18A1 ANKRD17 EIF2A

3.53e-06203108735012549
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

ILF3 OBSL1 APC SPICE1 NCOR2 PBRM1 KMT2A ANKRD17 EIF2A PPP6R2 MARCKS

5.09e-066391081123443559
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

EXOSC9 ILF3 PDHA1 FNBP4 OBSL1 SUCLG1 TRIP12 ARHGEF40 TKFC PBRM1 FRG1 ASPH ALDH18A1 KMT2A ANKRD17 MARCKS

5.21e-0613711081636244648
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

INCENP APC TRIP12 RABL6 ALDH18A1 CAMSAP1 AKAP1 SPEN PCDH10 TASOR SDK1 MARCKS

5.59e-067771081235844135
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

HYOU1 INCENP ACAT1 PDHA1 TRIP12 PBRM1 ALDH18A1 KMT2A ANKRD17 SPEN VCL

6.25e-066531081122586326
Pubmed

CAMSAP1 breaks the homeostatic microtubule network to instruct neuronal polarity.

L1CAM CAMSAP3 CAMSAP1

6.28e-0612108332839317
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

BIN1 ILF3 HYOU1 ACAT1 PDHA1 L1CAM CAMSAP3 APC GRIN2A SUCLG1 SLC1A2 KMT2A PPP6R2 UNC13A WNK2 VCL

8.90e-0614311081637142655
Pubmed

Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.

ACSM2A ACSM2B

9.55e-062108219634011
Pubmed

Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome.

APC RECQL4

9.55e-062108215703196
Pubmed

Overexpression of motor protein KIF17 enhances spatial and working memory in transgenic mice.

GRIN2A KIF17

9.55e-062108212391294
Pubmed

The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.

ACSM2A ACSM2B

9.55e-062108216521160
Pubmed

Regional bias of tumor suppressor gene mutations of STARD8 and WNK2 in colon cancers.

STARD8 WNK2

9.55e-062108238091885
Pubmed

Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.

ACSM2A ACSM2B

9.55e-062108229948332
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

BIN1 L1CAM CAMSAP3 APC GRIN2A SLC1A2 PPP6R2 MARCKS

1.34e-05347108817114649
Pubmed

Interaction network of human early embryonic transcription factors.

HYOU1 SCAND1 BCOR SKI NCOR2 PBRM1 KMT2A SPEN

1.46e-05351108838297188
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

ILF3 HYOU1 ACAT1 RBM33 MICALL1 MGAT2 ASF1B FRG1 ASPH EIF2A AKAP1 ITM2B MARCKS

1.51e-0510071081334597346
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

KIAA0232 CAMSAP3 APC TRIP12 TAB3 SPICE1 MICALL1 KMT2A ANKRD17 BOD1L1 CAMSAP1 AKAP1

1.56e-058611081236931259
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

HYOU1 RBM33 APC TAB3 RABL6 HGS CAMSAP1

1.90e-05263108734702444
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ILF3 INCENP ACAT1 PDHA1 TRIP12 PLCD3 NCOR2 ARHGEF40 RECQL4 ASPH ALDH18A1 ANKRD17 AP1G2 EIF2A VCL

1.93e-0513531081529467282
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

INCENP BAZ2B BCOR TRIP12 PBRM1 ASF1B FRG1 KMT2A BOD1L1 SPEN

2.07e-056081081036089195
Pubmed

A human MAP kinase interactome.

EXOSC9 RBM33 KIAA0232 APC EVPL SLC1A2 HGS ANKRD17 WNK2

2.17e-05486108920936779
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

OBSL1 BCOR TRIP12 PBRM1 SPEN

2.38e-05109108533554859
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

NFS1 SKI TELO2 AP3M2 OSBPL11 CDH3

2.40e-05183108631932471
Pubmed

KIF17 stabilizes microtubules and contributes to epithelial morphogenesis by acting at MT plus ends with EB1 and APC.

APC KIF17

2.86e-053108220696710
Pubmed

Structural insights into the recruitment of SMRT by the corepressor SHARP under phosphorylative regulation.

NCOR2 SPEN

2.86e-053108224268649
Pubmed

Absence of post-translational aspartyl beta-hydroxylation of epidermal growth factor domains in mice leads to developmental defects and an increased incidence of intestinal neoplasia.

APC ASPH

2.86e-053108211773073
Pubmed

Linkage of open eyelids with linkage group VII of the mouse.

HGS MYO15A

2.86e-05310825690495
Pubmed

Ablation of p57+ Quiescent Cancer Stem Cells Suppresses Recurrence after Chemotherapy of Intestinal Tumors.

CDKN1C APC

2.86e-053108236880956
Pubmed

A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters.

BCOR NCOR2

2.86e-053108223911289
Pubmed

Comparison of the fertility of tumor suppressor gene-deficient C57BL/6 mouse strains reveals stable reproductive aging and novel pleiotropic gene.

APC RECQL4

2.86e-053108234117297
Pubmed

Regulation of microtubule minus-end dynamics by CAMSAPs and Patronin.

CAMSAP3 CAMSAP1

2.86e-053108224706919
Pubmed

The CKK domain (DUF1781) binds microtubules and defines the CAMSAP/ssp4 family of animal proteins.

CAMSAP3 CAMSAP1

2.86e-053108219508979
Pubmed

NMDA receptor function and NMDA receptor-dependent phosphorylation of huntingtin is altered by the endocytic protein HIP1.

HIP1 GRIN2A

2.86e-053108217329427
Pubmed

Drosophila split ends homologue SHARP functions as a positive regulator of Wnt/beta-catenin/T-cell factor signaling in neoplastic transformation.

APC SPEN

2.86e-053108217234755
Pubmed

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.

APC CDH24 CDH3

3.19e-052010837806582
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

EXOSC9 ILF3 HYOU1 INCENP EVPL TRIP12 FRG1 ASPH ALDH18A1 ANKRD17 CRYBG1 EIF2A SPEN MARCKS

3.56e-0512571081436526897
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

HYOU1 DYNC2H1 OBSL1 TRIP12 ARHGEF40 MGAT2 TELO2 TRABD CLPTM1 ASPH ANKRD17 ITM2B

3.74e-059421081231073040
Pubmed

DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169.

ACAT1 KIAA0232 OBSL1 ASPH ALDH18A1

4.09e-05122108530773093
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FNBP4 NUDCD3 BCOR RGP1 STAB1 MICALL1 TELO2 ANKRD17 WNK2

4.20e-05529108914621295
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

HYOU1 INCENP ACAT1 L1CAM APC TRIP12 ARHGEF40 CLPTM1 HGS ASPH ALDH18A1 BOD1L1 AKAP1 MARCKS

4.99e-0512971081433545068
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

CAMSAP3 APC BCOR NCOR2 ANKRD17 CAMSAP1 AKAP1 TASOR

5.03e-05418108834709266
Pubmed

Transcriptional activity of Sp1 is regulated by molecular interactions between the zinc finger DNA binding domain and the inhibitory domain with corepressors, and this interaction is modulated by MEK.

BCOR NCOR2

5.71e-054108215878880
Pubmed

Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export.

NCOR2 SPEN

5.71e-054108216129689
Pubmed

The murine Bin1 gene functions early in myogenesis and defines a new region of synteny between mouse chromosome 18 and human chromosome 2.

BIN1 APC

5.71e-054108210036185
Pubmed

NFAR-1 and -2 modulate translation and are required for efficient host defense.

ILF3 EIF2A

5.71e-054108218337511
Pubmed

Agonist-antagonist induced coactivator and corepressor interplay on the human androgen receptor.

NCOR2 SPEN

5.71e-054108215062576
Pubmed

Expression of Acsm2, a kidney-specific gene, parallels the function and maturation of proximal tubular cells.

ACSM2A ACSM2B

5.71e-054108232830538
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

EXOSC9 ILF3 FNBP4 EVPL TRIP12 PBRM1 ASPH ALDH18A1 KMT2A ANKRD17 TASOR

6.76e-058471081135850772
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

REX1BD PDHA1 DYNC2H1 APC NUDCD3 TRIP12 FRG1 OSBPL11 ALDH18A1 ANKRD17 AKAP1 PPP6R2

6.95e-0510051081219615732
Pubmed

Genomic analysis of mouse retinal development.

BIN1 ILF3 APC SCAND1 DDC STAB1 PLCD3 NCOR2 ASF1B HGS KMT2A ZFYVE26

7.02e-0510061081215226823
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

EXOSC9 ILF3 FNBP4 APC TRIP12 PBRM1 ANKRD17 CAMSAP1

7.19e-05440108834244565
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

HYOU1 KIAA0232 CAMSAP3 APC TAB3 MICALL1 HGS CAMSAP1 EIF2A PPP6R2 VCL

7.20e-058531081128718761
Pubmed

Large-scale concatenation cDNA sequencing.

BIN1 ILF3 OBSL1 APC SLC1A2 SPICE1 OSBPL11 CDT1 SDK1

7.24e-0556810899110174
Pubmed

A "double adaptor" method for improved shotgun library construction.

BIN1 ILF3 OBSL1 APC SLC1A2 SPICE1 OSBPL11 CDT1 SDK1

7.84e-0557410898619474
Pubmed

Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.

COL6A3 BIN1 NCOR2 SDK1 WNK2

8.41e-05142108519851296
Pubmed

Association of genetic variants with hemorrhagic stroke in Japanese individuals.

COL6A3 BIN1 NCOR2 SDK1 WNK2

8.69e-05143108520198315
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

ACAT1 PDHA1 RBM33 BCOR SUCLG1 NCOR2 TKFC ANKRD17

9.35e-05457108832344865
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

RBM33 DYNC2H1 OBSL1 APC NUDCD3 BCOR NCOR2 PPP6R2 SPEN

9.42e-05588108938580884
Pubmed

A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer.

APC EIF2A

9.50e-055108231685988
Pubmed

L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer.

L1CAM APC

9.50e-055108232656539
Pubmed

Analysis of pyruvate dehydrogenase expression in embryonic mouse brain: localization and developmental regulation.

ACAT1 PDHA1

9.50e-05510827510589
Pubmed

Wdr47, Camsaps, and Katanin cooperate to generate ciliary central microtubules.

CAMSAP3 CAMSAP1

9.50e-055108234608154
Pubmed

Mint represses transactivation of the type II collagen gene enhancer through interaction with alpha A-crystallin-binding protein 1.

NCOR2 SPEN

9.50e-055108215778499
Pubmed

Microtubule minus-end stabilization by polymerization-driven CAMSAP deposition.

CAMSAP3 CAMSAP1

9.50e-055108224486153
Pubmed

Functional proteomics mapping of a human signaling pathway.

FNBP4 SKI TRIP12 PLCD3 NCOR2 PBRM1 CAMSAP1 SDK1 VCL

9.78e-05591108915231748
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

BAZ2B CAMSAP3 IGDCC3 EVPL TRIP12 RECQL4 PKHD1 ALDH18A1 BOD1L1 PCDH10

1.02e-047361081029676528
Pubmed

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.

BCOR NCOR2 ALDH18A1 SPEN

1.05e-0478108428611094
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

OBSL1 APC BCOR ANKRD17 CAMSAP1 TASOR

1.13e-04242108634011540
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

ILF3 PDHA1 APC SUCLG1 TRIP12 SPICE1 NCOR2 HGS ALDH18A1 ANKRD17 PPP6R2 CDH3 VCL

1.33e-0412471081327684187
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

BIN1 STARD8 ACAT1 PDHA1 RBM33 CAMSAP3 ARHGEF40 ALDH18A1 KMT2A AKAP1 MARCKS

1.35e-049161081132203420
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

INCENP APC TRIP12 CDT1 EIF2A VCL

1.35e-04250108633536335
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

EXOSC9 ILF3 HYOU1 INCENP ACAT1 PDHA1 DYNC2H1 PBRM1 ALDH18A1 BOD1L1 SPEN ITM2B MARCKS VCL

1.35e-0414251081430948266
Pubmed

Genetic and molecular control of folate-homocysteine metabolism in mutant mice.

APC SKI

1.42e-046108212016514
Pubmed

Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium.

CDKN1C APC

1.42e-046108235314700
Pubmed

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.

NCOR2 SPEN

1.42e-046108225915022
Pubmed

Overstimulation of NMDA receptors impairs early brain development in vivo.

L1CAM SLC1A2

1.42e-046108222606296
Pubmed

Kinesin Kif3b mutation reduces NMDAR subunit NR2A trafficking and causes schizophrenia-like phenotypes in mice.

APC GRIN2A

1.42e-046108231746486
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

OBSL1 BCOR SKI SUCLG1 NCOR2 ARHGEF40 PBRM1 TELO2 TRABD ANKRD17 SIGLEC1 UNC80

1.85e-0411161081231753913
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

PDHA1 L1CAM NCOR2 CLPTM1 CDH3

1.85e-04168108530631154
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

INCENP TRIP12 SPICE1 PBRM1 ASF1B FRG1 KMT2A CAMSAP1 SPEN

1.88e-04645108925281560
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

ILF3 BAZ2B FNBP4 BCOR SKI TRIP12 NCOR2 PBRM1 FRG1 ASPH KMT2A SPEN TASOR

1.92e-0412941081330804502
Pubmed

Wdr47 Controls Neuronal Polarization through the Camsap Family Microtubule Minus-End-Binding Proteins.

CAMSAP3 CAMSAP1

1.99e-047108232320668
Pubmed

DAP-1, a novel protein that interacts with the guanylate kinase-like domains of hDLG and PSD-95.

APC GRIN2A

1.99e-04710829286858
Pubmed

The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling.

NCOR2 SPEN

1.99e-047108211867749
Pubmed

Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex.

ACAT1 PDHA1

1.99e-047108224486017
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

ILF3 HYOU1 INCENP ACAT1 PDHA1 RBM33 OBSL1 NUDCD3 NFS1 SUCLG1 TELO2 TRABD OSBPL11 AKAP1

2.23e-0414961081432877691
InteractionNUP43 interactions

INCENP BAZ2B APC BCOR SUCLG1 TRIP12 NCOR2 PBRM1 ASF1B FRG1 RECQL4 KMT2A BOD1L1 EIF2A PPP6R2 SPEN

1.47e-0762510516int:NUP43
InteractionKCNA3 interactions

ILF3 HYOU1 APC SPICE1 MICALL1 RABL6 HGS PKHD1 ALDH18A1 KMT2A ANKRD17 BOD1L1 CAMSAP1 EIF2A SPEN MARCKS VCL

2.51e-0687110517int:KCNA3
InteractionTOP3B interactions

HIP1 HYOU1 PDHA1 RBM33 PPRC1 L1CAM MICALL1 PLCD3 RABL6 NCOR2 ARHGEF40 TKFC KCNH2 KCNK5 ANKRD17 AP1G2 ZFYVE26 CAMSAP1 EIF2A SPEN WNK2 AGTRAP

5.66e-06147010522int:TOP3B
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

L1CAM OBSL1 IGDCC3 SIGLEC1 SDK1

2.82e-04161655593
CoexpressionGSE17721_CTRL_VS_PAM3CSK4_8H_BMDC_UP

HIP1 ACAT1 SPICE1 NCOR2 MGAT2 FRG1 OSBPL11 ITM2B

1.38e-062001048M3743
CoexpressionDOUGLAS_BMI1_TARGETS_UP

HIP1 ILF3 HYOU1 BCOR SUCLG1 RABL6 NCOR2 CDH24 RECQL4 OSBPL11 KMT2A CPXM1

2.47e-0656310412M15103
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CAMSAP3 CCDC141 SLC1A2 PKHD1 CDH3 WNK2

6.45e-0618910765d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

L1CAM CAMSAP3 GRIN2A KMT2A UNC13A UNC80

6.65e-061901076416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellkidney_cells-CKD+DKD_normotensive|kidney_cells / Celltypes from Cells and Nuclei per compartment and clinical group

BIN1 ACAT1 SUCLG1 DDC IDNK ACSM2B

7.27e-061931076522a301bb48a5c40def7e0b58b2a2c13d85ac7a1
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPRC1 KCNK5 ALDH18A1 AKAP1 SDK1 WNK2

8.17e-061971076d6c9da7a3a6d2bcb13e2fc6605c8a59e7fb121c5
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

HYOU1 OBSL1 CCDC141 ASPH AP1G2 AKAP1

8.17e-0619710761485933986921ff45669d9b7501c8d17050b3e97
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPRC1 KCNK5 ALDH18A1 AKAP1 SDK1 WNK2

8.17e-06197107680b05c8ad9c1edc5dea3236079372475431343fe
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

OBSL1 CCDC141 TRABD ASPH AP1G2 AKAP1

8.17e-0619710761a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CAMSAP3 OBSL1 CCDC141 TRABD AP1G2 AKAP1

8.91e-062001076e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate|5w / Sample Type, Dataset, Time_group, and Cell type.

L1CAM CAMSAP3 TTL KMT2A UNC13A WNK2

8.91e-062001076c92e4fc0442404481fcac623d691dae6215b852d
ToppCellSigmoid-Dendritic_cell-cycling_DCs|Dendritic_cell / Region, Cell class and subclass

STAB1 NCOR2 ASF1B ASPH MARCKS AGTRAP

8.91e-062001076372fe9018481a4e9ac6ab3af43705a48238c4376
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate|6m / Sample Type, Dataset, Time_group, and Cell type.

CDKN1C ILF3 FNBP4 TRIM55 BOD1L1 SPEN

8.91e-0620010767c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

INCENP DYNC2H1 PKNOX2 ALDH18A1 CDH3

2.09e-051381075f33cc2a5033aed5d02d175db5e521046a8e11b6c
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 MYO15A UNC80 WNK2 ACSM2B

2.65e-05145107596712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC1A2 STAB1 MYO15A CDH3 MARCKS

4.24e-0516010750544bc465af208da448858d6e174ff56f2e08a46
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PKHD1 SIGLEC1 UNC80 WNK2 ACSM2B

4.50e-051621075bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BIN1 INCENP STAB1 KIF17 SDK1

4.50e-051621075ec29c6f1c31e41ddcb041a49c593910edaf0532c
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INCENP STAB1 RECQL4 PKHD1 OSBPL11

5.05e-051661075bb8135119dc37fdbba476599a56d368f422688dc
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

INCENP DYNC2H1 ASF1B CDT1 KIF17

5.98e-0517210757c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMSAP3 OBSL1 EVPL CPXM1 PCDH10

6.14e-0517310752b448acd5e584f24567204c31b8d74715e92f32a
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMSAP3 OBSL1 EVPL CPXM1 PCDH10

6.14e-0517310755086edc29c5a6137ca09877929a1317f9739c801
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Drd1_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PPRC1 NFS1 PBRM1 TELO2 EIF2A

6.66e-0517610753c76a5c4ca2b378667cb155fbb9675519572b35d
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKNOX2 PKHD1 ACSM2A SDK1 GPR176

7.03e-051781075544379f5a6145429762258d426b876bb36c112f5
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

L1CAM CAMSAP3 EVPL KCNK5 SIGLEC1

7.41e-051801075da723df348d7b8449bb1124f23fe6fa706412adb
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

L1CAM CAMSAP3 EVPL KCNK5 SIGLEC1

7.41e-0518010755b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

L1CAM CAMSAP3 EVPL KCNK5 SIGLEC1

7.41e-05180107550758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

BIN1 SCAND1 KCNH2 AP3M2 EIF2A

8.01e-051831075317b756378a9efd8ecb754acf7273f83f996e106
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 MYO15A PCDH10 SDK1 UNC80

8.22e-0518410752cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 MYO15A PCDH10 SDK1 UNC80

8.22e-051841075ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 MYO15A PCDH10 SDK1 UNC80

8.22e-0518410752b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DDC KCNH2 UNC13A UNC80 WNK2

8.65e-051861075b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BIN1 PKHD1 KCNK5 ACSM2A ACSM2B

8.87e-051871075dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BIN1 PKHD1 KCNK5 ACSM2A ACSM2B

8.87e-051871075f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellMonocytes-M2-like_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

BAZ2B CCDC141 STAB1 SIGLEC1 MARCKS

8.87e-05187107559e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

PKHD1 KCNK5 ACSM2A SDK1 ACSM2B

9.32e-0518910750be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MKRN3 TRIP12 ARHGEF40 BOD1L1

9.57e-05991074a815a887094204de30b299e8907e81ad9a39c016
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 KCNK5 ACSM2A SDK1 ACSM2B

9.80e-0519110753c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 KCNK5 ACSM2A SDK1 ACSM2B

9.80e-0519110751c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCelldroplet-Spleen-SPLEEN-30m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKRN3 INCENP DDC ASF1B SDK1

9.80e-051911075c8b99bd3a30c81ee4deba9cbf0196920ab3ab550
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

ILF3 RECQL4 HGS KMT2A BOD1L1

1.00e-0419210759cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 ANKRD17 ACSM2A SDK1 ACSM2B

1.00e-041921075e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

L1CAM TRIM55 PKHD1 CRYBG1 VCL

1.05e-04194107546070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

L1CAM TRIM55 PKHD1 CRYBG1 VCL

1.05e-041941075abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BIN1 TESPA1 TRABD AP3M2 KMT2A

1.08e-0419510754b9663509cc5e3f409f6d0d37640cb301a827d98
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CCDC141 STAB1 SIGLEC1 ITM2B MARCKS

1.08e-0419510754008fa86b5166087a4b20f89ae07e1dfc87c855d
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

L1CAM GRIN2A KIF17 UNC13A UNC80

1.08e-041951075ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APC SKI STAB1 ARHGEF40 MARCKS

1.08e-041951075a1478021a3ed0e779716393124ca2a7770c433b7
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYNC2H1 DDC KMT2A BOD1L1 UNC80

1.08e-0419510753e519cffa6144a62b06124642a14c9ff39b76554
ToppCellCOVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL6A3 GRIN2A PCDH10 SDK1 GPR176

1.08e-0419510753d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYNC2H1 DDC KMT2A BOD1L1 UNC80

1.08e-0419510757796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CCDC141 STAB1 SIGLEC1 ITM2B MARCKS

1.11e-041961075e8c4eeb4b6c6d9bccca2adb942d4cfbaab39636c
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EVPL CCDC141 SLC1A2 PKHD1 CDH3

1.13e-04197107522b26bac3a99b20c73bfa6e6f81026d064eaa9e8
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DDC KCNH2 PCDH10 UNC13A UNC80

1.13e-0419710753a0e97bfebe82f9687d518baaad7f20d0ffea8a1
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

EVPL RECQL4 KCNK5 CDT1 CDH3

1.13e-04197107549689a03ab31e53386dbe15c77c09ca3a14ebf4e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BIN1 ACAT1 SUCLG1 ACSM2A ACSM2B

1.16e-04198107564d73804902a043bdf66b413b769e853d111c033
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KCNH2 PCDH10 UNC13A UNC80 WNK2

1.16e-0419810758f25e8dff42bad8e779ca618bdb1cb1610667962
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BIN1 SUCLG1 DDC ACSM2A ACSM2B

1.16e-04198107572733b6149b797ac11cc108bc80428b77fbbba78
ToppCellTracheal-10x5prime-Endothelial-Endothelia_lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

STARD8 CCDC141 STAB1 ACSM2A ACSM2B

1.16e-04198107505429f18e1d74880c1835568c86177f661b3477a
ToppCellTracheal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

STARD8 CCDC141 STAB1 ACSM2A ACSM2B

1.16e-041981075306e28d31fd587409a12dcccc6b2abd7dc9c2e0a
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KCNH2 PCDH10 UNC13A UNC80 WNK2

1.16e-041981075e3e0aa3ef20b2370f5b133048510677aaa562dfa
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BIN1 ACAT1 SUCLG1 ACSM2A ACSM2B

1.16e-0419810757db113a6e7962ff26c1e1a43baa1a4230cf5f393
ToppCellParenchyma_COVID-19|World / Sample group, Lineage and Cell type

CDKN1C COL6A3 STAB1 CPXM1 MARCKS

1.16e-04198107545ab554e6d0399b3182f089a25b2adf96de1144b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BIN1 SUCLG1 DDC ACSM2A ACSM2B

1.16e-041981075f23559ce6072e3c323f6791ff95269271b0f7ff1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BIN1 ACAT1 SUCLG1 ACSM2A ACSM2B

1.16e-0419810758777117249077d4964dd7566aebde7c443475c7e
ToppCellCOVID-19_Mild-Classical_Monocyte|COVID-19_Mild / Disease condition and Cell class

STAB1 ARHGEF40 SIGLEC1 MARCKS AGTRAP

1.16e-04198107530ada3de865b6fb2b14196a1cbfd4740c6a57ce3
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL6A3 BAZ2B KCNH2 CDH3 VCL

1.19e-041991075e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SUCLG1 DDC KCNK5 ACSM2A ACSM2B

1.19e-0419910754bde35e5df019189433d65d415e29a0c1145ac66
ToppCellBAL-Control-cDC_0|Control / Compartment, Disease Groups and Clusters

SKI STAB1 ASPH SIGLEC1 AGTRAP

1.19e-0419910754518ffa51ead9da1ddf07bf048b18602e50f0f84
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-CD8+_Tcm|Leuk-UTI / Disease, condition lineage and cell class

TESPA1 AP3M2 KCNK5 ALDH18A1 KMT2A

1.19e-0419910756a1d84f61e1efaab541910926d6911122372659f
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Dividing_Basal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ASF1B RECQL4 CDT1 CDH3 WNK2

1.19e-041991075f0c289523957258d16135c04679db379d43d28d9
ToppCellTransverse-Dendritic_cell-cycling_DCs|Dendritic_cell / Region, Cell class and subclass

INCENP STAB1 ASF1B CDT1 MARCKS

1.22e-042001075617a6a42f7b31eb3c45bdceaf55a591b6de7f154
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RBM33 TRIP12 KMT2A BOD1L1 SIGLEC1

1.22e-04200107512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellInfluenza-Influenza_Severe-Lymphocyte-T/NK-CD4+_T_naive|Influenza_Severe / Disease, condition lineage and cell class

NUDCD3 CCDC141 TESPA1 AP3M2 MYO15A

1.22e-0420010750382f8fc27d18003761725e714beb6b3f3150057
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

STAB1 SIGLEC1 ITM2B MARCKS AGTRAP

1.22e-042001075bffebc281a5c1c2bfdb2696a45343787289fc374
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ACAT1 SUCLG1 DDC ACSM2A ACSM2B

1.22e-042001075825aad08431dd6b54aa636ace6efc821dfaf8014
DiseaseX-21319 measurement

ACSM2A ACSM2B

1.25e-0521052EFO_0800807
DiseaseX-11478 measurement

ACSM2A ACSM2B

3.75e-0531052EFO_0021242
Diseasebody surface area

EXOSC9 RGP1 TRIP12 NCOR2 ARHGEF40 KCNH2 CLPTM1 PKHD1 KCNK5 TASOR

1.01e-0464310510EFO_0022196
Disease3-hydroxyhexanoate measurement

ACSM2A ACSM2B

1.25e-0451052EFO_0800378
Diseaseindoleacetoylcarnitine measurement

ACSM2A ACSM2B

1.86e-0461052EFO_0800106
Diseasesudden cardiac arrest

BAZ2B GRIN2A PKHD1 AP1G2

2.24e-04831054EFO_0004278
DiseaseNephroblastoma

CDKN1C COL6A3 BCOR

2.87e-04361053C0027708
DiseaseHereditary hearing loss and deafness

PDHA1 SUCLG1 TMPRSS3 MYO15A

1.87e-031461054cv:C0236038
Diseaseintraocular pressure measurement

COL6A3 DYNC2H1 PKHD1 KCNK5 KMT2A CPXM1 BOD1L1

2.32e-035091057EFO_0004695
DiseaseDisproportionate short stature

CDKN1C DYNC2H1 OBSL1

2.65e-03771053C0878659
Diseasecholangiocarcinoma (is_implicated_in)

APC ASPH

2.77e-03221052DOID:4947 (is_implicated_in)
Diseaseepilepsy (implicated_via_orthology)

L1CAM GRIN2A KCNH2 UNC13A

2.78e-031631054DOID:1826 (implicated_via_orthology)
Diseasenephrotic syndrome (biomarker_via_orthology)

ACAT1 DDC

3.29e-03241052DOID:1184 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
ATPDKVPAAEQIPEA

UNC13A

406

Q9UPW8
AVPAQSSEPSIVVEP

nan

186

Q6ZRG5
DTAEPATAEAAVAPP

AKAP1

401

Q92667
PEAAVLEVSEPPAEA

ARHGEF40

326

Q8TER5
AQPAAVEVAKPVDFP

BAZ2B

1691

Q9UIF8
PAVVETAVISSPDPV

ACSM2A

486

Q08AH3
VQEAASVPEPAVPAD

CT47B1

196

P0C2W7
AQLSEAAPVPTEPQA

AP1G2

606

O75843
NVDEVPDIEPAALPQ

CDT1

336

Q9H211
DAVFPANSDPETPVL

CPXM1

226

Q96SM3
APPEDNPVEDSQVIV

ASPH

281

Q12797
PAVAAVAGPPAAAEV

ANKRD17

21

O75179
LIPAAAPQEPDTFED

DDC

41

P20711
FVERQPVSEPPADQV

BCOR

1106

Q6W2J9
VRADVVPQQADPEFP

CAMSAP1

546

Q5T5Y3
ATPAPAARAPAEEEV

CAMSAP3

956

Q9P1Y5
LVVPSAPPQEEAEAE

ARRDC1

306

Q8N5I2
ADVEEPAVPQTPRVA

RBM33

936

Q96EV2
EPVPAAEGPATVQSV

RABL6

376

Q3YEC7
QERATEAENVPPVIP

AP3M2

36

P53677
AAAVTVLEPPASDPE

OBSL1

96

O75147
QVAEPPVRVVAPEAA

OBSL1

1261

O75147
EAASVPEPAVPADLA

CT47A1

191

Q5JQC4
APAAASEEAAFPPVV

NCOR2

686

Q9Y618
SDSLAEIPAVDPNFP

PBRM1

801

Q86U86
VEPSDDVAVPGQPIV

IGDCC3

46

Q8IVU1
AVPADTAAAPEVGPV

NFS1

41

Q9Y697
VSQVAPAAPVEPETF

GPR176

431

Q14439
EAEPVAAAEPEVPEN

INCENP

381

Q9NQS7
SVPVPEFADSDPANI

ITM2B

131

Q9Y287
SAASLVPAVPQPEAD

MGAT2

71

Q10469
AAAAEKEPVPVPVQE

NUDCD3

101

Q8IVD9
AEEAPLVEFPAEIQP

FSCB

321

Q5H9T9
PVAAPVLAQDQASPE

MYO15A

2536

Q9UKN7
PGAVVVDVDLTPAAP

KCNH2

191

Q12809
VRVAVQDAPEPPAFT

CDH24

361

Q86UP0
IAEAEPPSEVVSTPV

EXOSC9

316

Q06265
PVESEDPAAAQASPA

PNMA6E

511

A0A0J9YXQ4
PIPSQVDIFEDPQAD

KIAA0232

1136

Q92628
AVARAPEDSSPAPEV

KCNK5

376

O95279
FEATLVQEAPIPAEP

EVPL

651

Q92817
TVVTPEAAPEKNPVD

L1CAM

706

P32004
APTPVEPEDVAQGEE

MICALL1

131

Q8N3F8
VPDTEVFETPEAQPG

PCDH10

981

Q9P2E7
VPIVNTNDAVVPPAE

ALDH18A1

216

P54886
EAPVGAEPAAEAPVA

PRR27

161

Q6MZM9
AEPAAEAPVAAEPAA

PRR27

166

Q6MZM9
EAPVAAEPAAEAPVG

PRR27

171

Q6MZM9
AEPAAEAPVGVEPAA

PRR27

176

Q6MZM9
SNPVPEDAAPGTVIA

PCDHAC1

346

Q9H158
AVPQEEGDPSVTPAE

BOD1L1

2271

Q8NFC6
EVDEGPSPPEQFTAV

FRG1

86

Q14331
NPFIPPDAASIVTEV

DYNC2H1

3376

Q8NCM8
ADAPNPSLIPETDAV

ASF1B

76

Q9NVP2
VIPPAGQTEDAEPIS

HYOU1

941

Q9Y4L1
EPPAAPENFIQISVD

IDNK

156

Q5T6J7
AQESVLPPPVAFADA

CCDC141

1261

Q6ZP82
VAVAVSPPLEPAAES

CDKN1C

111

P49918
AAPVAAPVAVAVLAP

CDKN1C

166

P49918
LVAPPPDEEANATSA

SLC1A2

196

P43004
PPPAVESDAADIVFL

COL6A3

1426

P12111
AVVAPAPVVEAVSTP

ILF3

491

Q12906
PEQEAAPAEEPAAAA

MARCKS

291

P29966
PPVVEPDINSTVEHD

KMT2A

2076

Q03164
PEVVSVASCAPPQEE

CRYBG1

586

Q9Y4K1
VPSEVPNEEPKVATA

EIF2A

431

Q9BY44
AEPGPAQPAEASEVA

BIN1

451

O00499
PADAPEAVTVVTIAP

SDK1

911

Q7Z5N4
VPSAPIDPQAQLEAD

PKNOX2

56

Q96KN3
PVDSVEADPTAVGPV

PPRC1

586

Q5VV67
VEDVNEAPVFVPPSK

CDH3

431

P22223
VTAAPAVAVPPEATV

PPP6R2

886

O75170
PVAVPEEQPVAESGL

OSBPL11

321

Q9BXB4
VIQPPENATAPVSDE

PGBD3

26

Q8N328
ARTDAPQADVPKVPV

KIF17

631

Q9P2E2
VDQEERSAAPEPIQP

TAB3

471

Q8N5C8
EIDAITAPQPAAPVG

FNBP4

151

Q8N3X1
DVRFPQDEAVAPSSP

RGP1

166

Q92546
AVAVEEDPPGEPVQA

RECQL4

291

O94761
LGPAPVSVAPQAEAE

SCAND1

76

P57086
VVVIPAEASSPDSEP

HIP1

311

O00291
TAEPPAETPAEIVDG

TELO2

461

Q9Y4R8
ADAAVEPIDFPIAPV

ACAT1

316

P24752
QIPDAGAPTVPAAVE

PKHD1

1256

P08F94
FETAVAPNVALAPPA

SKI

411

P12755
QPAVLAPAQAPAEAE

STARD8

381

Q92502
APAQAPAEAEPVAQE

STARD8

386

Q92502
PAEAEPVAQEEAEAP

STARD8

391

Q92502
PPPFAAAAINEAIEA

SUCLG1

121

P53597
DSPERPVVNANVSVP

SPICE1

476

Q8N0Z3
QCVPAAEAEPPAVSE

TASOR

1001

Q9UK61
PAVVETAVISSPDPV

ACSM2B

486

Q68CK6
AEDPVSEVPAVSQHP

APC

1316

P25054
SGEDPTAAAPVAEVP

CLPTM1

601

O96005
IDSAEAPADPFAVPE

AGTRAP

136

Q6RW13
ISPVAPDADAVAAQI

TMPRSS3

26

P57727
ALPPAADAPVTQGEV

TRIM55

401

Q9BYV6
TFIEAQPEPAAAPTD

UNC80

3111

Q8N2C7
AAHIEPPTQEVAEAP

MKRN3

146

Q13064
ASEPAPAPVEQLEQV

SPEN

1686

Q96T58
IEDAAQFATADPEPP

PDHA1

346

P08559
AAEPTVPAVPAAEEA

REX1BD

6

Q96EN9
PPVAAQVAAQVAAPV

PLCD3

16

Q8N3E9
EANVEPVVPSEASEP

TRABD

11

Q9H4I3
AAPTNVVENPLPETD

HGS

366

O14964
VAATAPPDAPNREEV

VCL

611

P18206
QAVLAPEAPPVAAGV

STAB1

2466

Q9NY15
APEAAVPEGAPITVT

SIGLEC1

1266

Q9BZZ2
NVFPPEVAVFEPSEA

TRB

141

P0DTU4
EEAAAALQDVPDPEP

TESPA1

31

A2RU30
TQEPGPDPIAAAVET

WNK2

121

Q9Y3S1
RVAPAEPQEAPDSTA

TKFC

351

Q3LXA3
VIVPQPEDPDRANTS

TRIP12

41

Q14669
VDIAISSVFPPPDVE

TTL

351

Q8NG68
QEPDAVDAPVPEHLS

ZFYVE26

476

Q68DK2
VENVTLPENVDFPDP

GRIN2A

1136

Q12879