Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	HGF TNFAIP3 ICAM1	2.58e-05	34	35	3	GO:1902042
GeneOntologyBiologicalProcess	response to actinomycin D	KAT7 MDM2	2.79e-05	5	35	2	GO:0072716
GeneOntologyBiologicalProcess	regulation of neuron projection regeneration	HGF RTN4RL1 ADAM17	6.90e-05	47	35	3	GO:0070570
GeneOntologyBiologicalProcess	regulation of extrinsic apoptotic signaling pathway via death domain receptors	HGF TNFAIP3 ICAM1	9.89e-05	53	35	3	GO:1902041
MousePheno	abnormal intromission	GRM7 ESR1	5.38e-05	5	33	2	MP:0031628
MousePheno	failure of ejaculation	GRM7 ESR1	8.06e-05	6	33	2	MP:0009856
MousePheno	abnormal mammary gland morphology	GPRC6A ADAM17 TNFAIP3 MDM2 ESR1	1.00e-04	201	33	5	MP:0000627
MousePheno	abnormal apocrine gland morphology	GPRC6A ADAM17 TNFAIP3 MDM2 ESR1	1.00e-04	201	33	5	MP:0013554
Domain	TIL	MUC5B FCGBP MUC5AC	1.43e-06	12	36	3	PF01826
Domain	C8	MUC5B FCGBP MUC5AC	1.43e-06	12	36	3	PF08742
Domain	Unchr_dom_Cys-rich	MUC5B FCGBP MUC5AC	1.86e-06	13	36	3	IPR014853
Domain	C8	MUC5B FCGBP MUC5AC	1.86e-06	13	36	3	SM00832
Domain	TIL_dom	MUC5B FCGBP MUC5AC	2.36e-06	14	36	3	IPR002919
Domain	VWFD	MUC5B FCGBP MUC5AC	3.62e-06	16	36	3	PS51233
Domain	VWD	MUC5B FCGBP MUC5AC	3.62e-06	16	36	3	SM00216
Domain	VWF_type-D	MUC5B FCGBP MUC5AC	3.62e-06	16	36	3	IPR001846
Domain	VWD	MUC5B FCGBP MUC5AC	3.62e-06	16	36	3	PF00094
Domain	VWC_out	MUC5B FCGBP MUC5AC	6.24e-06	19	36	3	SM00215
Domain	VWC	MUC5B FCGBP MUC5AC	5.30e-05	38	36	3	SM00214
Domain	WxxW_domain	MUC5B MUC5AC	5.39e-05	6	36	2	IPR025155
Domain	Mucin2_WxxW	MUC5B MUC5AC	5.39e-05	6	36	2	PF13330
Domain	VWF_dom	MUC5B FCGBP MUC5AC	7.17e-05	42	36	3	IPR001007
Domain	PAN	HGF KLKB1	7.54e-05	7	36	2	PS50948
Domain	Pan_app	HGF KLKB1	7.54e-05	7	36	2	IPR003609
Domain	PAN_1	HGF KLKB1	7.54e-05	7	36	2	PF00024
Domain	Hirudin/antistatin	NAGPA MUC5AC	7.54e-05	7	36	2	IPR011061
Domain	NCD3G	GPRC6A GRM7	2.78e-04	13	36	2	PF07562
Domain	GPCR_3_9-Cys_dom	GPRC6A GRM7	2.78e-04	13	36	2	IPR011500
Domain	GPCR_3_CS	GPRC6A GRM7	3.24e-04	14	36	2	IPR017979
Domain	Glyco_hormone_CN	MUC5B MUC5AC	3.73e-04	15	36	2	IPR006208
Domain	Cys_knot	MUC5B MUC5AC	3.73e-04	15	36	2	PF00007
Domain	CTCK_1	MUC5B MUC5AC	5.42e-04	18	36	2	PS01185
Domain	GPCR_3	GPRC6A GRM7	7.41e-04	21	36	2	IPR000337
Domain	G_PROTEIN_RECEP_F3_4	GPRC6A GRM7	8.14e-04	22	36	2	PS50259
Domain	zf-RanBP	NEIL3 MDM2	8.14e-04	22	36	2	PF00641
Domain	7tm_3	GPRC6A GRM7	8.14e-04	22	36	2	PF00003
Domain	CT	MUC5B MUC5AC	8.14e-04	22	36	2	SM00041
Domain	GPCR_3_C	GPRC6A GRM7	8.14e-04	22	36	2	IPR017978
Domain	G_PROTEIN_RECEP_F3_2	GPRC6A GRM7	8.14e-04	22	36	2	PS00980
Domain	G_PROTEIN_RECEP_F3_3	GPRC6A GRM7	8.14e-04	22	36	2	PS00981
Domain	G_PROTEIN_RECEP_F3_1	GPRC6A GRM7	8.14e-04	22	36	2	PS00979
Domain	ZF_RANBP2_2	NEIL3 MDM2	8.91e-04	23	36	2	PS50199
Domain	ZF_RANBP2_1	NEIL3 MDM2	9.71e-04	24	36	2	PS01358
Domain	Cys_knot_C	MUC5B MUC5AC	1.05e-03	25	36	2	IPR006207
Domain	Znf_RanBP2	NEIL3 MDM2	1.05e-03	25	36	2	IPR001876
Domain	CTCK_2	MUC5B MUC5AC	1.05e-03	25	36	2	PS01225
Domain	VWC	MUC5B MUC5AC	1.32e-03	28	36	2	PF00093
Domain	VWFC_1	MUC5B MUC5AC	2.18e-03	36	36	2	PS01208
Domain	ANF_receptor	GPRC6A GRM7	2.31e-03	37	36	2	PF01094
Domain	ANF_lig-bd_rcpt	GPRC6A GRM7	2.31e-03	37	36	2	IPR001828
Domain	VWFC_2	MUC5B MUC5AC	2.43e-03	38	36	2	PS50184
Domain	Peripla_BP_I	GPRC6A GRM7	2.56e-03	39	36	2	IPR028082
Pubmed	Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).	MUC5B MUC5AC	1.04e-06	2	36	2	7513696
Pubmed	The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.	MUC5B MUC5AC	1.04e-06	2	36	2	37146737
Pubmed	MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.	MUC5B MUC5AC	1.04e-06	2	36	2	14988081
Pubmed	Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.	MUC5B MUC5AC	1.04e-06	2	36	2	15563276
Pubmed	The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.	MUC5B MUC5AC	1.04e-06	2	36	2	17621824
Pubmed	Muc5b is required for airway defence.	MUC5B MUC5AC	1.04e-06	2	36	2	24317696
Pubmed	Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.	MUC5B MUC5AC	1.04e-06	2	36	2	22391959
Pubmed	Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.	MUC5B MUC5AC	1.04e-06	2	36	2	35776514
Pubmed	Estrogen receptor α (ERα) mediates 17β-estradiol (E2)-activated expression of HBO1.	KAT7 ESR1	1.04e-06	2	36	2	21040551
Pubmed	The ocular surface phenotype of Muc5ac and Muc5b null mice.	MUC5B MUC5AC	1.04e-06	2	36	2	24327612
Pubmed	Gel-forming mucins form distinct morphologic structures in airways.	MUC5B MUC5AC	1.04e-06	2	36	2	28607090
Pubmed	Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.	MUC5B MUC5AC	1.04e-06	2	36	2	31030254
Pubmed	The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.	MUC5B MUC5AC	1.04e-06	2	36	2	23527003
Pubmed	Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.	MUC5B MUC5AC	1.04e-06	2	36	2	16540890
Pubmed	Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.	MUC5B MUC5AC	1.04e-06	2	36	2	27845589
Pubmed	Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.	MUC5B MUC5AC	1.04e-06	2	36	2	27435107
Pubmed	Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.	MUC5B MUC5AC	1.04e-06	2	36	2	26871672
Pubmed	Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM-17) mediates the ectodomain cleavage of intercellular adhesion molecule-1 (ICAM-1).	ADAM17 ICAM1	1.04e-06	2	36	2	16332693
Pubmed	In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.	MUC5B MUC5AC	1.04e-06	2	36	2	11587997
Pubmed	Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.	MUC5B MUC5AC	1.04e-06	2	36	2	34656442
Pubmed	Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.	MUC5B MUC5AC	1.04e-06	2	36	2	34058148
Pubmed	Tumor necrosis factor alpha-converting enzyme mediates MUC5AC mucin expression in cultured human airway epithelial cells.	ADAM17 MUC5AC	1.04e-06	2	36	2	12972643
Pubmed	C-Mannosylation of MUC5AC and MUC5B Cys subdomains.	MUC5B MUC5AC	1.04e-06	2	36	2	14718370
Pubmed	Intrinsic ubiquitin E3 ligase activity of histone acetyltransferase Hbo1 for estrogen receptor α.	KAT7 ESR1	1.04e-06	2	36	2	28769019
Pubmed	Mucin production during prenatal and postnatal murine lung development.	MUC5B MUC5AC	1.04e-06	2	36	2	21653907
Pubmed	TRIAD1 is negatively regulated by the MDM2 E3 ligase.	MDM2 ARIH2	1.04e-06	2	36	2	22940738
Pubmed	MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.	MUC5B MUC5AC	1.04e-06	2	36	2	36427316
Pubmed	MDM2 regulates estrogen receptor α and estrogen responsiveness in breast cancer cells.	MDM2 ESR1	1.04e-06	2	36	2	21169420
Pubmed	Histone acetyltransferase Hbo1 destabilizes estrogen receptor α by ubiquitination and modulates proliferation of breast cancers.	KAT7 ESR1	1.04e-06	2	36	2	24125069
Pubmed	Mucin deficiency causes functional and structural changes of the ocular surface.	MUC5B MUC5AC	1.04e-06	2	36	2	23272068
Pubmed	Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.	MUC5B MUC5AC	1.04e-06	2	36	2	27729120
Pubmed	Discovery of Potent Small-Molecule USP8 Inhibitors for the Treatment of Breast Cancer through Regulating ERα Expression.	USP8 ESR1	1.04e-06	2	36	2	35786929
Pubmed	De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.	MUC5B MUC5AC	1.04e-06	2	36	2	36111525
Pubmed	Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.	MUC5B MUC5AC	1.04e-06	2	36	2	32348677
Pubmed	Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.	MUC5B MUC5AC	1.04e-06	2	36	2	24332705
Pubmed	High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.	MUC5B MUC5AC	3.12e-06	3	36	2	29286856
Pubmed	Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.	MUC5B MUC5AC	3.12e-06	3	36	2	36675209
Pubmed	Human neutrophil elastase induces MUC5AC overexpression in chronic rhinosinusitis through tumour necrosis factor-α converting enzyme.	ADAM17 MUC5AC	3.12e-06	3	36	2	26881964
Pubmed	Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.	MUC5B MUC5AC	3.12e-06	3	36	2	29802623
Pubmed	p53-independent activation of the hdm2-P2 promoter through multiple transcription factor response elements results in elevated hdm2 expression in estrogen receptor alpha-positive breast cancer cells.	MDM2 ESR1	3.12e-06	3	36	2	12750288
Pubmed	Crucial role of estrogen for the mammalian female in regulating semen coagulation and liquefaction in vivo.	KLKB1 ESR1	3.12e-06	3	36	2	28414719
Pubmed	Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.	MUC5B MUC5AC	3.12e-06	3	36	2	29604272
Pubmed	MDM2 enhances the function of estrogen receptor alpha in human breast cancer cells.	MDM2 ESR1	3.12e-06	3	36	2	11178989
Pubmed	Aquaporin 5 expression increases mucin production in lung adenocarcinoma.	MUC5B MUC5AC	3.12e-06	3	36	2	21455588
Pubmed	Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.	MUC5B MUC5AC	3.12e-06	3	36	2	20422702
Pubmed	Mucin gene polymorphisms in otitis media patients.	MUC5B MUC5AC	3.12e-06	3	36	2	19718741
Pubmed	Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.	MUC5B MUC5AC	3.12e-06	3	36	2	27776277
Pubmed	Neutrophil elastase induces MUC5AC mucin production in human airway epithelial cells via a cascade involving protein kinase C, reactive oxygen species, and TNF-alpha-converting enzyme.	ADAM17 MUC5AC	3.12e-06	3	36	2	16148149
Pubmed	TRIAD1 inhibits MDM2-mediated p53 ubiquitination and degradation.	MDM2 ARIH2	3.12e-06	3	36	2	22819825
Pubmed	Estrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer.	MDM2 ESR1	3.12e-06	3	36	2	26909605
Pubmed	Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.	MUC5B MUC5AC	3.12e-06	3	36	2	34158522
Pubmed	Estrogen receptor α promotes Cav1.2 ubiquitination and degradation in neuronal cells and in APP/PS1 mice.	MDM2 ESR1	3.12e-06	3	36	2	31012223
Pubmed	Differential regulation of estrogen receptor alpha turnover and transactivation by Mdm2 and stress-inducing agents.	MDM2 ESR1	3.12e-06	3	36	2	17545634
Pubmed	IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.	MUC5B MUC5AC	3.12e-06	3	36	2	19596978
Pubmed	Effects of cytokines derived from cancer-associated fibroblasts on androgen synthetic enzymes in estrogen receptor-negative breast carcinoma.	HGF ESR1	3.12e-06	3	36	2	28831645
Pubmed	Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.	MUC5B MUC5AC	3.12e-06	3	36	2	19556605
Pubmed	Paracrine Met signaling triggers epithelial-mesenchymal transition in mammary luminal progenitors, affecting their fate.	HGF ICAM1	3.12e-06	3	36	2	26165517
Pubmed	Estrogen receptor protects p53 from deactivation by human double minute-2.	MDM2 ESR1	3.12e-06	3	36	2	10766163
Pubmed	Relationship between estrogen receptor-alpha polymorphism and serum levels of vascular cell adhesion molecule-1, intercellular adhesion molecule-1, C-reactive protein and homocysteine in postmenopausal women.	ESR1 ICAM1	6.24e-06	4	36	2	17891599
Pubmed	Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.	MUC5B MUC5AC	6.24e-06	4	36	2	25638393
Pubmed	Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.	MUC5B MUC5AC	6.24e-06	4	36	2	22269464
Pubmed	Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways.	MUC5B MUC5AC	6.24e-06	4	36	2	18258655
Pubmed	LPS increases MUC5AC by TACE/TGF-α/EGFR pathway in human intrahepatic biliary epithelial cell.	ADAM17 MUC5AC	6.24e-06	4	36	2	24027752
Pubmed	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.	MUC5B MUC5AC	6.24e-06	4	36	2	23807779
Pubmed	Spiro-oxindole derivative 5-chloro-4',5'-diphenyl-3'-(4-(2-(piperidin-1-yl) ethoxy) benzoyl) spiro[indoline-3,2'-pyrrolidin]-2-one triggers apoptosis in breast cancer cells via restoration of p53 function.	MDM2 ESR1	6.24e-06	4	36	2	26556313
Pubmed	Self-control of HGF regulation on human trophoblast cell invasion via enhancing c-Met receptor shedding by ADAM10 and ADAM17.	HGF ADAM17	6.24e-06	4	36	2	22689693
Pubmed	ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.	MUC5B MUC5AC	6.24e-06	4	36	2	31582416
Pubmed	Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.	MUC5B MUC5AC	6.24e-06	4	36	2	17471237
Pubmed	MCP-1/CCR2B-dependent loop upregulates MUC5AC and MUC5B in human airway epithelium.	MUC5B MUC5AC	6.24e-06	4	36	2	21097527
Pubmed	The mouse secreted gel-forming mucin gene cluster.	MUC5B MUC5AC	6.24e-06	4	36	2	14984930
Pubmed	TGF-β₂ decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cells.	MUC5B MUC5AC	6.24e-06	4	36	2	23249391
Pubmed	Human Neutrophil Elastase Mediates MUC5AC Hypersecretion via the Tumour Necrosis Factor-α Converting Enzyme-Epidermal Growth Factor Receptor Signalling Pathway in vivo.	ADAM17 MUC5AC	6.24e-06	4	36	2	34130299
Pubmed	Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.	MUC5B MUC5AC	6.24e-06	4	36	2	29869461
Pubmed	Signal pathway of 17beta-estradiol-induced MUC5B expression in human airway epithelial cells.	MUC5B ESR1	6.24e-06	4	36	2	18688042
Pubmed	Gene polymorphisms of TNF-238G/A, TNF-308G/A, IL10-1082G/A, TNFAIP3, and MC4R and comorbidity occurrence in a Romanian population with psoriasis.	MC4R TNFAIP3	6.24e-06	4	36	2	29696068
Pubmed	Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.	MUC5B MUC5AC	6.24e-06	4	36	2	12676567
Pubmed	Polymorphism of human mucin genes in chest disease: possible significance of MUC2.	MUC5B MUC5AC	1.04e-05	5	36	2	11062147
Pubmed	Differential expression of MUC genes in endometrial and cervical tissues and tumors.	MUC5B MUC5AC	1.04e-05	5	36	2	16188033
Pubmed	Estrogen receptor-dependent proteasomal degradation of the glucocorticoid receptor is coupled to an increase in mdm2 protein expression.	MDM2 ESR1	1.04e-05	5	36	2	12897156
Pubmed	The human Cathelicidin LL-37 induces MUC5AC mucin production by airway epithelial cells via TACE-TGF-α-EGFR pathway.	ADAM17 MUC5AC	1.04e-05	5	36	2	24901072
Pubmed	Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease.	HGF KLKB1	1.04e-05	5	36	2	10962009
Pubmed	Unusual proteolytic activation of pro-hepatocyte growth factor by plasma kallikrein and coagulation factor XIa.	HGF KLKB1	1.04e-05	5	36	2	12372819
Pubmed	Dysregulation of Mdm2 and Mdm4 alternative splicing underlies motor neuron death in spinal muscular atrophy.	MDM2 GRM7	1.04e-05	5	36	2	30012555
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC5B MUC5AC	1.56e-05	6	36	2	19110483
Pubmed	CCL20/CCR6 feedback exaggerates epidermal growth factor receptor-dependent MUC5AC mucin production in human airway epithelial (NCI-H292) cells.	ADAM17 MUC5AC	1.56e-05	6	36	2	21300824
Pubmed	A protein interaction landscape of breast cancer.	MUC5B TRMT1L DCTN4 MDM2 ESR1 ICAM1	4.38e-05	634	36	6	34591612
Pubmed	The repertoire of olfactory C family G protein-coupled receptors in zebrafish: candidate chemosensory receptors for amino acids.	GPRC6A GRM7	4.66e-05	10	36	2	17156446
Pubmed	Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study.	MUC5B MUC5AC	5.70e-05	11	36	2	24429156
Pubmed	Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways.	MUC5B MUC5AC	9.41e-05	14	36	2	22797898
Pubmed	Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia.	FCGBP ICAM1	9.41e-05	14	36	2	32385093
Pubmed	Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders.	BICD2 USP8	1.08e-04	15	36	2	24482476
Pubmed	A phenotype-sensitizing Apoe-deficient genetic background reveals novel atherosclerosis predisposition loci in the mouse.	TNFAIP3 ESR1	1.08e-04	15	36	2	11973313
Pubmed	Differential regulation of NF-κB-mediated proviral and antiviral host gene expression by primate lentiviral Nef and Vpu proteins.	HGF ICAM1	1.24e-04	16	36	2	25620704
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC5B MUC5AC	1.58e-04	18	36	2	18834073
Pubmed	Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.	MDM2 UHRF2 ARIH2	1.78e-04	105	36	3	22493164
Pubmed	HIV-Nef and ADAM17-Containing Plasma Extracellular Vesicles Induce and Correlate with Immune Pathogenesis in Chronic HIV Infection.	ADAM17 ICAM1	2.16e-04	21	36	2	27211553
Pubmed	Characterization of 458 single nucleotide polymorphisms of disease candidate genes in the Korean population.	MUC5B ICAM1	2.38e-04	22	36	2	12768436
Pubmed	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	MTMR3 ZPBP ICAM1	2.38e-04	116	36	3	21102463
Pubmed	Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.	ADAM17 MDM2 ESR1	2.44e-04	117	36	3	19124506
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	KAT7 ARHGAP32 MDM2 KALRN ESR1	2.48e-04	552	36	5	10737800
Interaction	SGK3 interactions	KAT7 TRMT1L ESR1 ICAM1	6.08e-06	69	35	4	int:SGK3
Interaction	TWF1 interactions	MUC5B DCTN4 MUC5AC ESR1 ICAM1	1.13e-05	172	35	5	int:TWF1
Interaction	ERBB4 interactions	USP8 ADAM17 MDM2 KALRN ESR1	1.56e-05	184	35	5	int:ERBB4
Interaction	TRIM8 interactions	BICD2 TNFAIP3 UHRF2 ESR1	2.66e-05	100	35	4	int:TRIM8
Cytoband	17q21.32	KAT7 TTLL6	6.87e-04	49	36	2	17q21.32
Cytoband	11p15.5	MUC5B MUC5AC	3.90e-03	118	36	2	11p15.5
GeneFamily	Zinc fingers RANBP2-type \|RNA binding motif containing	NEIL3 MDM2	3.79e-04	21	25	2	89
GeneFamily	CD molecules\|Mucins	MUC5B MUC5AC	3.79e-04	21	25	2	648
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	R3HDML KALRN GRM7 ESR1	8.51e-06	161	36	4	b9a63fc9becc44d305fc7c221283bf59ec06b10f
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Microglia/Mac\|Myeloid_cells / Location, Cell class and cell subclass	KAT7 MUC5AC DISP1 ESR1	1.03e-05	169	36	4	dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Microglia/Mac\|metastatic_Lymph_Node / Location, Cell class and cell subclass	FCGBP MUC5AC DISP1 ESR1	1.10e-05	172	36	4	f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|356C / Donor, Lineage, Cell class and subclass (all cells)	MUC5B FCGBP MUC5AC ZNF648	1.18e-05	175	36	4	4bfae78ac3a2cb9404382aae96d291504a9cfa14
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	MUC5B FCGBP MUC5AC ZNF648	1.18e-05	175	36	4	af9c5104c86231cfdb93a0f7d7032379efaa009e
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MUC5B FCGBP MUC5AC ZNF648	1.24e-05	177	36	4	709235694cc711b9b79690e23c94577b2ae06811
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MUC5B FCGBP MUC5AC ZNF648	1.24e-05	177	36	4	7f9c2a45a994b32f15e5693f7cb873716a4eb568
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP32 MUC5B MUC5AC ZNF648	1.29e-05	179	36	4	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HGF KALRN HOXD11 ESR1	1.53e-05	187	36	4	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	facs-Skin-nan-18m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFAIP3 FCGBP ESR1 ICAM1	1.60e-05	189	36	4	6c71e81373cb7822de23c193a6350b6df9f567bc
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC ZNF648	1.67e-05	191	36	4	529068029fb461df766135576dd0d8b5980f9bc0
ToppCell	Bronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MC4R ARHGAP32 MUC5B FCGBP	1.81e-05	195	36	4	fc2a1d84b3d013e5cb9e7b9cdd740e4010897d20
ToppCell	Bronchial-10x5prime-Epithelial-Epi_submucosal-gland\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MC4R MUC5B FCGBP MUC5AC	1.88e-05	197	36	4	e2c820c4e4a6cd01ceb020473286e3f5d4e3718e
ToppCell	Biopsy_Control_(H.)-Epithelial-MUC5AC+_High\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	MUC5B FCGBP MUC5AC ZNF648	1.96e-05	199	36	4	a5240868cea40574ed4ee45eb27a00c1812957ed
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-hematologic-erythrocytic\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HGF R3HDML TTLL6	1.43e-04	126	36	3	cd02f3d4a3fadd24f3a298639b392f0354d227d2
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-hematologic\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HGF R3HDML TTLL6	1.43e-04	126	36	3	f2ec5aa6c649ae1ff99519f6897cf207dc292edf
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-hematologic-erythrocytic-erythrocyte\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HGF R3HDML TTLL6	1.43e-04	126	36	3	61a7e400cbc81691b21cd3c37376c1d19fec2270
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3-Excitatory_Neuron.Slc17a7.Pvrl3-Nos1_(CA3_Principal_cells)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	HGF FCGBP R3HDML	1.50e-04	128	36	3	9128b633879d21de2ebe651384cfec6d2c3c2932
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MUC5B FCGBP ZNF648	2.49e-04	152	36	3	1b2a39ae159e79f1fb18d6d164bd7acab5299fca
ToppCell	normal_Lymph_Node-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	ADAM17 TNFAIP3 ICAM1	2.54e-04	153	36	3	5424494ea1f09542799045a875cc3eac13de5079
ToppCell	18-Airway-Epithelial-Goblet-like_secretory\|Airway / Age, Tissue, Lineage and Cell class	MTMR3 MUC5B FCGBP	2.54e-04	153	36	3	14a60220e169ce642771636de982a7b02e5b2608
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC	2.63e-04	155	36	3	62b59cb32b12bd55b19e98786a866d788fc9e4bf
ToppCell	facs-Heart-Unknown-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF KLKB1 ZPBP	2.73e-04	157	36	3	2ac4695d9e4ca8d4ba19c555e9a1d86ac8f398ab
ToppCell	facs-Heart-Unknown-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF KLKB1 ZPBP	2.73e-04	157	36	3	8a393eece90fb9a1b7c356736bdb36277261fbd3
ToppCell	facs-Heart-Unknown-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF KLKB1 ZPBP	2.73e-04	157	36	3	8d30d8e6fae93afcada6bd68799439335cd65b69
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	BICD2 TNFAIP3 HSF5	3.11e-04	164	36	3	de1646dbcf2a10b48e021acf7dc63e803e6a47ce
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MUC5B FCGBP MUC5AC	3.16e-04	165	36	3	baff639a7046fb5cacb70f341b6d24cef3519f8e
ToppCell	Club-club-12\|World / Class top	MUC5B FCGBP MUC5AC	3.16e-04	165	36	3	9b7a31cbdcd2f96b8bd08a4cd4141b92bd5e9062
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MUC5B FCGBP MUC5AC	3.16e-04	165	36	3	6fdce8b23736409a23884ef3918638ffc067a86f
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MUC5B FCGBP MUC5AC	3.16e-04	165	36	3	dd4d36ff8efb89fee1fb4c48d1b8f46902119909
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC	3.22e-04	166	36	3	60060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC	3.22e-04	166	36	3	ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC	3.22e-04	166	36	3	4586d6725403f879fc96f67be579022587ce1906
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC	3.28e-04	167	36	3	31633899aae852873a4887e72c621474b0a51a33
ToppCell	Adult-Epithelial-lung_goblet_cell-D122\|Adult / Lineage, Cell type, age group and donor	MUC5B FCGBP MUC5AC	3.28e-04	167	36	3	6efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell	Club_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	MUC5B FCGBP ZNF648	3.28e-04	167	36	3	dbdaaeb3bd9139cb008d9fe24ec031fc5628f136
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP ICAM1	3.28e-04	167	36	3	8fede587572d465cb63f7828141a574185bbb819
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC	3.34e-04	168	36	3	b275e951ff7109e36da22fc17bd4516f9b9432c4
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC	3.34e-04	168	36	3	0757a5af953901a8faed5774ffec4755fc9c0a6e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HGF KALRN ESR1	3.34e-04	168	36	3	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC	3.34e-04	168	36	3	a0dbe2ee697e29b32aa5f8326445e067ff66c154
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC	3.39e-04	169	36	3	db73dae011ff3749b3706e50ab46d03b775dd6bb
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC	3.39e-04	169	36	3	97b7047b87ce0052d8580565c9b44fd2aa6f0d5c
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC	3.39e-04	169	36	3	1a684471dbda42e1470e5a889648666e14f25982
ToppCell	droplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN KLKB1 ZPBP	3.45e-04	170	36	3	10e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCell	Myeloid-Myeloid-D_(Mast_cell)\|Myeloid / shred on cell class and cell subclass (v4)	HGF TNFAIP3 DISP1	3.51e-04	171	36	3	5f1aafc4c55a9c6c3153430186a8a351425a3cb9
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cel\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCGBP R3HDML TTLL6	3.57e-04	172	36	3	c0bda7153e02bee7d0326138cc684151c404c2a1
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP32 NEIL3 KALRN	3.63e-04	173	36	3	12f779b8dce79431b2d1002ba524dd3f9566aeb0
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC	3.63e-04	173	36	3	e8afef5ae68983eb8d6515b43952636a47e9d3d4
ToppCell	droplet-Lung-21m-Epithelial-airway_epithelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FCGBP R3HDML TTLL6	3.63e-04	173	36	3	a809be2630d2b91b53b82b5e2bb99e05524597c1
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC	3.63e-04	173	36	3	e4d9a9a781acc531bc81c3fcee24d637e805c8e1
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC	3.63e-04	173	36	3	3aa1d28d4814798a772808ed29e1dbbdf92abd03
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCGBP ZPBP ICAM1	3.63e-04	173	36	3	7c5e4809205ce1a0a301c15442af00a2e2b9b301
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MDM2 NAGPA HSF5	3.63e-04	173	36	3	506efcaa5afd6ed5e565c4c4def6a4505fea97c5
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	MUC5B FCGBP MUC5AC	3.70e-04	174	36	3	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM4\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	TMEFF1 HGF MDM2	3.70e-04	174	36	3	9191f6abb37ca65da5105f91e21689d11ec1059b
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM4-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TMEFF1 HGF MDM2	3.70e-04	174	36	3	fe105550a43b935affc73e32796115d20328a2f8
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	R3HDML GRM7 ESR1	3.76e-04	175	36	3	9a96794df049d8228fea57c1584c160191d36b56
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HGF RTN4RL1 GPRC6A	3.76e-04	175	36	3	fb91a45763e4c48d993094a13088ffc19f1e2574
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HGF RTN4RL1 GPRC6A	3.76e-04	175	36	3	2a53d4f140d5ab096efe8118d8aa351db7838b49
ToppCell	facs-Skin-nan-24m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFAIP3 FCGBP ICAM1	3.76e-04	175	36	3	21542be95059983d2c8bdf01ec711fdbf1ec1f62
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	ADAM17 KALRN HSF5	3.82e-04	176	36	3	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	droplet-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTN4RL1 ARHGAP32 GPRC6A	3.88e-04	177	36	3	65709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC5B FCGBP MUC5AC	3.88e-04	177	36	3	779ba86f53650772755b52460be03f18bb204e55
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC5B FCGBP MUC5AC	3.88e-04	177	36	3	0f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B FCGBP MUC5AC	3.88e-04	177	36	3	2af09028014f4ec3b7d2a4c286f1ae5e84a9f590
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTN4RL1 ARHGAP32 GPRC6A	3.88e-04	177	36	3	8684d47a547e2a06496f15e8da0200ecddc431e0
ToppCell	(5)_Glands_mucous\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	MUC5B FCGBP MUC5AC	3.95e-04	178	36	3	f0f19b0d78f2cc5df4d4c321a953a6e447d5114a
ToppCell	Club_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	MUC5B FCGBP MUC5AC	3.95e-04	178	36	3	be64d4be23fb96a4cdd7980c58880fdfe817747f
ToppCell	15-Trachea-Epithelial-Goblet-like_secretory\|Trachea / Age, Tissue, Lineage and Cell class	MUC5B FCGBP MUC5AC	3.95e-04	178	36	3	f0557920b9b3e7c4f39938d1b524aa58711af4d2
ToppCell	3'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TNFAIP3 HSF5 ICAM1	4.01e-04	179	36	3	9dd8d19050223cdebec2579014892b759e5e9de8
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	MUC5B FCGBP MUC5AC	4.01e-04	179	36	3	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	facs-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF RTN4RL1 GPRC6A	4.01e-04	179	36	3	7078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCell	nucseq-Epithelial-Epithelial_Glandular\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC5B FCGBP MUC5AC	4.01e-04	179	36	3	859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCell	facs-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF RTN4RL1 GPRC6A	4.01e-04	179	36	3	d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCell	(5)_Epithelial_cells-(5)_Glands_mucous\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	MUC5B FCGBP MUC5AC	4.08e-04	180	36	3	a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC5B FCGBP MUC5AC	4.08e-04	180	36	3	3dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC5B FCGBP MUC5AC	4.08e-04	180	36	3	668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCell	PBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KAT7 HGF DCTN4	4.15e-04	181	36	3	2b9b460239d67fd480cee60820cdb306109d3567
ToppCell	PBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KAT7 HGF DCTN4	4.15e-04	181	36	3	2a1aa4a0ec7bc367857beaff543135e4345c835b
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RTN4RL1 TNFAIP3 ICAM1	4.21e-04	182	36	3	63b41b538b26bc899558807fd035e543611f8c52
ToppCell	Club-club-8\|World / Class top	MUC5B FCGBP MUC5AC	4.21e-04	182	36	3	8111d917e588008d947021460ddf8f1e7ae1337a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HGF KALRN ESR1	4.21e-04	182	36	3	44764676ed3f51ba171ce63f669390392fa50a43
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MUC5B FCGBP MUC5AC	4.21e-04	182	36	3	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HGF KALRN ESR1	4.21e-04	182	36	3	d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MUC5B FCGBP MUC5AC	4.28e-04	183	36	3	514b72a1ae55656934839800513385e19bc240e2
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGF KLKB1 ZPBP	4.28e-04	183	36	3	d2074b13b4831ec18c81273d9a1ff673c3f6a16d
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	MUC5B FCGBP MUC5AC	4.28e-04	183	36	3	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	Epithelial-lung_goblet_cell\|World / Lineage, Cell type, age group and donor	MUC5B FCGBP MUC5AC	4.28e-04	183	36	3	940cbe298e9c53b5622af09264586ed823d3141f
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MUC5B FCGBP MUC5AC	4.35e-04	184	36	3	49eccf72725593a8fb4a529e7985a5c413b3ca6a
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MUC5B FCGBP MUC5AC	4.35e-04	184	36	3	41164109d9d7bb1c431220e2e85e08dc5f56856d
ToppCell	Control-Epithelial_cells-Airway_goblet\|Control / group, cell type (main and fine annotations)	MUC5B FCGBP MUC5AC	4.35e-04	184	36	3	d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC	4.35e-04	184	36	3	01c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell	facs-Heart-LV-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCGBP R3HDML HOXD11	4.42e-04	185	36	3	a835f821a5e6568d648df831ec4c2d0048d67093
ToppCell	HSPCs-Eo/Baso_prog.\|HSPCs / Lineage and Cell class	HGF TNFAIP3 ICAM1	4.42e-04	185	36	3	1ae29c0077bfc57e8896e59a21f20af43e7ff5b7
ToppCell	facs-Heart-LV-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCGBP R3HDML HOXD11	4.42e-04	185	36	3	386b08bcb304db543e3c5ff75f85e99bf0c592df
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B FCGBP MUC5AC	4.42e-04	185	36	3	5dee5645240637e135677732a35fd416b37367d4
ToppCell	21-Trachea-Epithelial-Goblet-like_secretory\|Trachea / Age, Tissue, Lineage and Cell class	MUC5B FCGBP MUC5AC	4.49e-04	186	36	3	f8cddad28896f0edf10a8645fa49a011b22b120d
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	USP8 TRMT1L NPAT	4.49e-04	186	36	3	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP32 KALRN GRM7	4.56e-04	187	36	3	f18628ffc7ff7c762b8339ba8822cf0c3157f469
Drug	trifluoperazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A	ADAM17 TNFAIP3 MDM2 MUC5AC ESR1 ICAM1	2.39e-07	168	36	6	1649_UP
Drug	AC1NDZPB	MC4R HGF ADAM17 TNFAIP3 NAGPA ICAM1	2.12e-06	244	36	6	CID004634228
Drug	kaempferol	HGF TNFAIP3 MUC5AC ESR1 ICAM1	3.59e-06	149	36	5	ctd:C006552
Drug	AC1O44ID	HGF TNFAIP3 ICAM1	6.29e-06	23	36	3	CID006324632
Drug	Foxgreen	HGF ADAM17 UHRF2 ICAM1	6.91e-06	78	36	4	CID000019190
Drug	trifluoperazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A_EA	TNFAIP3 MUC5AC ESR1 ICAM1 ARIH2	7.24e-06	172	36	5	910_UP
Drug	AI-I	HOXD11 ESR1	7.28e-06	3	36	2	CID000002238
Drug	Methyl benzethonium chloride [25155-18-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A	MTMR3 TNFAIP3 HOXD11 GRM7 ICAM1	1.09e-05	187	36	5	3943_UP
Drug	radicicol; Down 200; 0.1uM; MCF7; HG-U133A	HGF TNFAIP3 ESR1 ICAM1 NPAT	1.33e-05	195	36	5	489_DN
Drug	Hydrochlorothiazide [58-93-5]; Up 200; 13.4uM; PC3; HG-U133A	USP8 TNFAIP3 TRMT1L ICAM1 ARIH2	1.43e-05	198	36	5	1906_UP
Drug	norgestomet	HGF ESR1	1.46e-05	4	36	2	ctd:C100284
Drug	ICI 3188	ADAM17 ESR1	1.46e-05	4	36	2	CID003085373
Drug	Verapamyl hydrochloride [152-11-4]; Up 200; 8.2uM; PC3; HT_HG-U133A	MUC5B ADAM17 TNFAIP3 MUC5AC ESR1	1.47e-05	199	36	5	6287_UP
Drug	A-I-J	MC4R ADAM17 ESR1	2.10e-05	34	36	3	CID000449208
Drug	AC1L1BIB	ADAM17 ESR1	2.42e-05	5	36	2	CID000001451
Drug	Dust	KAT7 ADAM17 TNFAIP3 ESR1 ICAM1	3.39e-05	237	36	5	ctd:D004391
Drug	PbCl2	TNFAIP3 GRM7 ESR1	4.60e-05	44	36	3	CID000024459
Drug	TAPI-2	ADAM17 MUC5AC	5.08e-05	7	36	2	ctd:C099410
Drug	Ethinyl Estradiol-Norgestrel Combination	ESR1 ICAM1	5.08e-05	7	36	2	ctd:D019304
Drug	Luteolin	TNFAIP3 MDM2 ESR1 ICAM1	5.51e-05	132	36	4	ctd:D047311
Drug	gemcitabine	ADAM17 TNFAIP3 MDM2 ESR1 ICAM1	6.31e-05	270	36	5	ctd:C056507
Drug	DIMBOA	KAT7 HGF ICAM1	6.36e-05	49	36	3	CID000002358
Drug	aminoglutethimide	MC4R HOXD11 ESR1 ICAM1	6.36e-05	137	36	4	CID000002145
Drug	rebamipide	HGF MUC5AC ICAM1	7.18e-05	51	36	3	CID000005042
Drug	AC1L1KQ5	HGF ESR1	8.69e-05	9	36	2	CID000005607
Drug	thioridazine hydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A_EA	MUC5B TNFAIP3 MUC5AC ICAM1	1.05e-04	156	36	4	1010_UP
Drug	M57-15	NAGPA ICAM1	1.32e-04	11	36	2	CID000087583
Drug	glycine	BICD2 GPRC6A GRM7 KLKB1	1.43e-04	169	36	4	CID000000750
Drug	phellopterin	TNFAIP3 ICAM1	1.59e-04	12	36	2	CID000098608
Drug	marimastat	HGF ADAM17 TNFAIP3	1.70e-04	68	36	3	CID000119031
Drug	Diethylstilbestrol [56-53-1]; Up 200; 15uM; MCF7; HT_HG-U133A	TNFAIP3 MDM2 HOXD11 ICAM1	1.79e-04	179	36	4	3895_UP
Drug	Ribavirin [36791-04-5]; Up 200; 16.4uM; HL60; HT_HG-U133A	MDM2 GRM7 ESR1 ICAM1	1.91e-04	182	36	4	3142_UP
Drug	felodipine; Up 200; 10uM; MCF7; HT_HG-U133A_EA	MTMR3 TNFAIP3 ESR1 ICAM1	1.91e-04	182	36	4	848_UP
Drug	Perphenazine [58-39-9]; Up 200; 10uM; MCF7; HT_HG-U133A	TNFAIP3 MDM2 HOXD11 ICAM1	1.99e-04	184	36	4	1540_UP
Drug	Suloctidil [54063-56-8]; Up 200; 11.8uM; PC3; HT_HG-U133A	TNFAIP3 MDM2 MUC5AC ICAM1	2.07e-04	186	36	4	6675_UP
Drug	Metixene hydrochloride [1553-34-0]; Up 200; 11.6uM; PC3; HT_HG-U133A	TNFAIP3 MDM2 GRM7 ICAM1	2.07e-04	186	36	4	6672_UP
Drug	Dicloxacillin sodium salt [13412-64-1]; Up 200; 8.2uM; MCF7; HT_HG-U133A	HGF ADAM17 MDM2 ESR1	2.11e-04	187	36	4	5012_UP
Drug	Propofol [2078-54-8]; Up 200; 22.4uM; MCF7; HT_HG-U133A	TNFAIP3 MDM2 ESR1 ICAM1	2.11e-04	187	36	4	3386_UP
Drug	Betulinic acid [472-15-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A	ADAM17 TNFAIP3 MDM2 ICAM1	2.16e-04	188	36	4	3281_UP
Drug	tibolone	ESR1 ICAM1	2.19e-04	14	36	2	ctd:C027385
Drug	Terfenadine [50679-08-8]; Down 200; 8.4uM; MCF7; HT_HG-U133A	BICD2 MDM2 ESR1 NPAT	2.29e-04	191	36	4	2227_DN
Drug	haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A_EA	ADAM17 NAGPA ESR1 NPAT	2.29e-04	191	36	4	1041_DN
Drug	Monobenzone [103-16-2]; Up 200; 20uM; MCF7; HT_HG-U133A	TNFAIP3 MDM2 MUC5AC ICAM1	2.34e-04	192	36	4	3391_UP
Drug	Orlistat; Up 200; 10uM; PC3; HT_HG-U133A	HGF MDM2 GRM7 ICAM1	2.34e-04	192	36	4	6388_UP
Drug	Trifluridine [70-00-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A	ADAM17 MDM2 ESR1 ICAM1	2.38e-04	193	36	4	7176_UP
Drug	Methyl benzethonium chloride [25155-18-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A	MTMR3 MDM2 ESR1 ICAM1	2.38e-04	193	36	4	3850_UP
Drug	Naftifine hydrochloride [65473-14-5]; Up 200; 12.4uM; MCF7; HT_HG-U133A	ADAM17 TNFAIP3 ESR1 ICAM1	2.43e-04	194	36	4	7032_UP
Drug	5707885; Up 200; 50uM; MCF7; HT_HG-U133A	TNFAIP3 GRM7 MUC5AC ICAM1	2.43e-04	194	36	4	6385_UP
Drug	Tribenoside [10310-32-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A	ADAM17 TNFAIP3 MDM2 ICAM1	2.43e-04	194	36	4	3507_UP
Drug	Norgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A	ADAM17 MDM2 ESR1 NPAT	2.43e-04	194	36	4	3606_DN
Drug	Loxapine succinate [27833-64-3]; Up 200; 9uM; MCF7; HT_HG-U133A	TNFAIP3 MDM2 ESR1 ICAM1	2.43e-04	194	36	4	5293_UP
Drug	Nifurtimox [23256-30-6]; Down 200; 14uM; MCF7; HT_HG-U133A	ADAM17 MDM2 ESR1 ARIH2	2.43e-04	194	36	4	4953_DN
Drug	pseudococaine	MC4R KAT7 ADAM17 TNFAIP3 GRM7 ICAM1	2.46e-04	570	36	6	CID000002826
Drug	Flunisolide [3385-03-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A	MTMR3 HGF TNFAIP3 ICAM1	2.48e-04	195	36	4	3828_UP
Drug	Loracarbef [121961-22-6]; Up 200; 10.8uM; PC3; HT_HG-U133A	HGF MDM2 GRM7 ESR1	2.48e-04	195	36	4	5073_UP
Drug	Phenazopyridine hydrochloride [136-40-3]; Up 200; 16uM; MCF7; HT_HG-U133A	MTMR3 TNFAIP3 ESR1 ARIH2	2.48e-04	195	36	4	6234_UP
Drug	Chlorprothixene hydrochloride [6469-93-8]; Up 200; 11.4uM; PC3; HT_HG-U133A	MTMR3 TNFAIP3 MDM2 ESR1	2.48e-04	195	36	4	6692_UP
Drug	Butylparaben [94-26-8]; Up 200; 20.6uM; MCF7; HT_HG-U133A	HGF TNFAIP3 MDM2 ESR1	2.48e-04	195	36	4	5608_UP
Drug	monensin; Down 200; 10.9uM; MCF7; HT_HG-U133A_EA	NEIL3 ADAM17 TRMT1L MDM2	2.48e-04	195	36	4	1105_DN
Drug	chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A	HGF ADAM17 ESR1 ARIH2	2.48e-04	195	36	4	6977_UP
Drug	I-o-T	NAGPA MUC5AC	2.52e-04	15	36	2	CID000447122
Drug	NSC98536	ARHGAP32 ESR1	2.52e-04	15	36	2	CID000004080
Drug	radicicol; Down 200; 0.1uM; MCF7; HT_HG-U133A	ADAM17 MDM2 GRM7 ESR1	2.53e-04	196	36	4	5947_DN
Drug	Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A	MC4R MTMR3 GRM7 ESR1	2.53e-04	196	36	4	3847_UP
Drug	Amoxapine [14028-44-5]; Up 200; 12.8uM; PC3; HT_HG-U133A	HGF KALRN GRM7 ICAM1	2.53e-04	196	36	4	6650_UP
Drug	Cyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; PC3; HT_HG-U133A	MUC5B TNFAIP3 ESR1 ICAM1	2.53e-04	196	36	4	4252_UP
Drug	Edrophonium chloride [116-38-1]; Up 200; 19.8uM; PC3; HT_HG-U133A	MDM2 GRM7 ESR1 ICAM1	2.53e-04	196	36	4	6655_UP
Drug	Cyproheptadine hydrochloride [969-33-5]; Up 200; 12.4uM; PC3; HT_HG-U133A	MTMR3 HGF ESR1 ICAM1	2.53e-04	196	36	4	6740_UP
Drug	Sulfacetamide sodic hydrate [6209-17-2]; Down 200; 15.8uM; MCF7; HT_HG-U133A	TNFAIP3 MDM2 ESR1 NPAT	2.53e-04	196	36	4	1695_DN
Drug	Estrone [53-16-7]; Up 200; 14.8uM; PC3; HT_HG-U133A	HGF TNFAIP3 ESR1 ICAM1	2.53e-04	196	36	4	6647_UP
Drug	Carisoprodol [78-44-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A	ARHGAP32 MDM2 ESR1 NPAT	2.53e-04	196	36	4	4955_DN
Drug	beta- Belladonnine dichloroethylate [191355-47-2]; Down 200; 6uM; MCF7; HT_HG-U133A	MDM2 NAGPA ESR1 ARIH2	2.53e-04	196	36	4	4984_DN
Drug	Amphotericin B [1397-89-3]; Up 200; 4.4uM; HL60; HT_HG-U133A	TNFAIP3 MDM2 ESR1 ICAM1	2.53e-04	196	36	4	2441_UP
Drug	Clemizole hydrochloride [1163-36-6]; Up 200; 11uM; MCF7; HT_HG-U133A	TNFAIP3 GRM7 MUC5AC ESR1	2.53e-04	196	36	4	2301_UP
Drug	Allantoin [97-59-6]; Up 200; 25.2uM; MCF7; HT_HG-U133A	MDM2 ESR1 ICAM1 NPAT	2.58e-04	197	36	4	1678_UP
Drug	Piroxicam [36322-90-4]; Up 200; 12uM; MCF7; HT_HG-U133A	MUC5B TNFAIP3 ESR1 ICAM1	2.58e-04	197	36	4	2252_UP
Drug	(+,-)-Octopamine hydrochloride [770-05-8]; Up 200; 21uM; HL60; HT_HG-U133A	ADAM17 MDM2 GRM7 ICAM1	2.58e-04	197	36	4	3112_UP
Drug	Epitiostanol [2363-58-8]; Down 200; 13uM; MCF7; HT_HG-U133A	ADAM17 TNFAIP3 ESR1 ARIH2	2.58e-04	197	36	4	7342_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A	HGF ADAM17 ICAM1 ARIH2	2.58e-04	197	36	4	6143_DN
Drug	alpha-estradiol; Down 200; 0.01uM; HL60; HT_HG-U133A	HGF ARHGAP32 ADAM17 ESR1	2.58e-04	197	36	4	6169_DN
Drug	15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A	NAGPA MUC5AC ESR1 ICAM1	2.58e-04	197	36	4	7521_UP
Drug	Meclofenamic acid sodium salt monohydrate [6385-02-0]; Up 200; 11.8uM; MCF7; HT_HG-U133A	NEIL3 ADAM17 MDM2 ESR1	2.58e-04	197	36	4	7038_UP
Drug	Enalapril maleate [76095-16-4]; Up 200; 8.2uM; MCF7; HT_HG-U133A	MTMR3 MDM2 MUC5AC ESR1	2.58e-04	197	36	4	7026_UP
Drug	Gliclazide [21187-98-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A	BICD2 ADAM17 MDM2 ESR1	2.58e-04	197	36	4	2870_DN
Drug	Torsemide [56211-40-6]; Up 200; 11.4uM; PC3; HT_HG-U133A	MDM2 GRM7 MUC5AC ESR1	2.58e-04	197	36	4	5057_UP
Drug	Propidium iodide [25535-16-4]; Down 200; 6uM; MCF7; HT_HG-U133A	NEIL3 TNFAIP3 NAGPA ARIH2	2.58e-04	197	36	4	6277_DN
Drug	PNU-0293363 [326823-19-2]; Up 200; 10uM; PC3; HT_HG-U133A	MDM2 MUC5AC ESR1 ICAM1	2.58e-04	197	36	4	6563_UP
Drug	Amyleine hydrochloride [532-59-2]; Down 200; 14.8uM; HL60; HG-U133A	BICD2 HGF ARHGAP32 DCTN4	2.58e-04	197	36	4	1991_DN
Drug	Dubinidine [22964-77-8]; Down 200; 14.6uM; MCF7; HT_HG-U133A	TNFAIP3 MDM2 ESR1 NPAT	2.63e-04	198	36	4	6250_DN
Drug	Lycorine hydrochloride [2188-68-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A	MTMR3 MDM2 GRM7 ESR1	2.63e-04	198	36	4	3891_UP
Drug	Oxaprozin [21256-18-8]; Up 200; 13.6uM; PC3; HT_HG-U133A	MTMR3 HOXD11 MUC5AC ESR1	2.63e-04	198	36	4	4530_UP
Drug	Nalidixic acid sodium salt hydrate; Down 200; 14.6uM; MCF7; HT_HG-U133A	ADAM17 ESR1 ICAM1 ARIH2	2.63e-04	198	36	4	2297_DN
Drug	0225151-0000 [351320-15-5]; Up 200; 10uM; MCF7; HT_HG-U133A	TNFAIP3 MDM2 GRM7 ESR1	2.63e-04	198	36	4	6384_UP
Drug	Fursultiamine Hydrochloride [2105-43-3]; Up 200; 9.2uM; PC3; HT_HG-U133A	MDM2 HOXD11 MUC5AC ESR1	2.63e-04	198	36	4	6630_UP
Drug	Dexamethasone acetate [1177-87-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A	TNFAIP3 MDM2 ESR1 NPAT	2.63e-04	198	36	4	6271_DN
Drug	Benfluorex hydrochloride [23642-66-2]; Up 200; 10.4uM; HL60; HT_HG-U133A	MDM2 ESR1 ICAM1 ARIH2	2.63e-04	198	36	4	1266_UP
Drug	Flunixin meglumine [42461-84-7]; Down 200; 8.2uM; MCF7; HT_HG-U133A	ADAM17 MDM2 ESR1 ICAM1	2.63e-04	198	36	4	4735_DN
Drug	6-Furfurylaminopurine [525-79-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A	HGF MUC5B TNFAIP3 ICAM1	2.63e-04	198	36	4	6073_UP
Drug	(-)-MK 801 hydrogen maleate [77086-19-2]; Up 200; 11.8uM; PC3; HT_HG-U133A	TNFAIP3 MDM2 MUC5AC ICAM1	2.63e-04	198	36	4	6657_UP
Drug	(S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; MCF7; HT_HG-U133A	ADAM17 MDM2 MUC5AC ICAM1	2.68e-04	199	36	4	4346_DN
Disease	cholangiocarcinoma (is_marker_for)	HGF MUC5B TNFAIP3 MDM2 MUC5AC	1.46e-08	64	36	5	DOID:4947 (is_marker_for)
Disease	biliary tract benign neoplasm (is_marker_for)	HGF MDM2 MUC5AC	5.82e-08	7	36	3	DOID:0050625 (is_marker_for)
Disease	Male sterility	MDM2 HOXD11 ESR1	2.78e-05	48	36	3	C0917731
Disease	Male infertility	MDM2 HOXD11 ESR1	2.78e-05	48	36	3	C0021364
Disease	Subfertility, Male	MDM2 HOXD11 ESR1	2.78e-05	48	36	3	C0848676
Disease	pancreatic ductal carcinoma (is_marker_for)	MUC5B MDM2 MUC5AC	5.72e-05	61	36	3	DOID:3587 (is_marker_for)
Disease	otitis media (is_marker_for)	MUC5B ICAM1	6.47e-05	10	36	2	DOID:10754 (is_marker_for)
Disease	pulmonary fibrosis	MUC5B MUC5AC	7.90e-05	11	36	2	EFO_0009448
Disease	neovascular inflammatory vitreoretinopathy (is_marker_for)	HGF ICAM1	9.48e-05	12	36	2	DOID:9719 (is_marker_for)
Disease	chronic obstructive pulmonary disease (is_marker_for)	MUC5B MUC5AC ICAM1	2.27e-04	97	36	3	DOID:3083 (is_marker_for)
Disease	Usual Interstitial Pneumonia	MUC5B ESR1	2.44e-04	19	36	2	C4721509
Disease	Hamman-Rich Disease	MUC5B ESR1	2.44e-04	19	36	2	C4721508
Disease	inflammatory bowel disease (is_implicated_in)	ADAM17 ICAM1	2.44e-04	19	36	2	DOID:0050589 (is_implicated_in)
Disease	pancreatic cancer (is_marker_for)	HGF MUC5AC ICAM1	2.56e-04	101	36	3	DOID:1793 (is_marker_for)
Disease	Familial Idiopathic Pulmonary Fibrosis	MUC5B ESR1	2.71e-04	20	36	2	C4721952
Disease	vitiligo (is_implicated_in)	HGF ESR1	3.00e-04	21	36	2	DOID:12306 (is_implicated_in)
Disease	Idiopathic Pulmonary Fibrosis	MUC5B ESR1	3.00e-04	21	36	2	C1800706
Disease	Sjogren's syndrome (is_marker_for)	MUC5AC ICAM1	3.93e-04	24	36	2	DOID:12894 (is_marker_for)
Disease	systemic scleroderma (is_implicated_in)	HGF ESR1	3.93e-04	24	36	2	DOID:418 (is_implicated_in)
Disease	Cerebral Astrocytoma	HGF ESR1	4.27e-04	25	36	2	C0750935
Disease	Intracranial Astrocytoma	HGF ESR1	4.27e-04	25	36	2	C0750936
Disease	Pilocytic Astrocytoma	HGF ESR1	4.27e-04	25	36	2	C0334583
Disease	Astrocytoma	HGF ESR1	4.27e-04	25	36	2	C0004114
Disease	Juvenile Pilocytic Astrocytoma	HGF ESR1	4.27e-04	25	36	2	C0280783
Disease	Diffuse Astrocytoma	HGF ESR1	4.27e-04	25	36	2	C0280785
Disease	Grade I Astrocytoma	HGF ESR1	4.27e-04	25	36	2	C1704230
Disease	Subependymal Giant Cell Astrocytoma	HGF ESR1	4.27e-04	25	36	2	C0205768
Disease	Mixed oligoastrocytoma	HGF ESR1	4.27e-04	25	36	2	C0547065
Disease	Childhood Cerebral Astrocytoma	HGF ESR1	4.27e-04	25	36	2	C0338070
Disease	Gemistocytic astrocytoma	HGF ESR1	4.62e-04	26	36	2	C0334581
Disease	Protoplasmic astrocytoma	HGF ESR1	4.62e-04	26	36	2	C0334580
Disease	Fibrillary Astrocytoma	HGF ESR1	4.62e-04	26	36	2	C0334582
Disease	asthma (is_marker_for)	MUC5B MUC5AC ICAM1	4.90e-04	126	36	3	DOID:2841 (is_marker_for)
Disease	Anaplastic astrocytoma	HGF ESR1	4.98e-04	27	36	2	C0334579
Disease	Alzheimer's disease (is_implicated_in)	ADAM17 ESR1 ICAM1	5.61e-04	132	36	3	DOID:10652 (is_implicated_in)
Disease	Neoplastic Cell Transformation	TNFAIP3 MDM2 ESR1	6.52e-04	139	36	3	C0007621
Disease	melanoma (is_marker_for)	ESR1 ICAM1	7.46e-04	33	36	2	DOID:1909 (is_marker_for)
Disease	hemorrhoid	BICD2 HOXD11 ESR1	7.67e-04	147	36	3	EFO_0009552
Disease	Autoinflammatory disorder	ADAM17 TNFAIP3	8.40e-04	35	36	2	C3860213
Disease	COVID-19 symptoms measurement	MUC5B MUC5AC	8.40e-04	35	36	2	EFO_0600019
Disease	serum non-albumin protein measurement	MTMR3 USP8 TNFAIP3 TTLL6	9.53e-04	361	36	4	EFO_0004568
Disease	pancreatitis (biomarker_via_orthology)	MDM2 ICAM1	1.04e-03	39	36	2	DOID:4989 (biomarker_via_orthology)
Disease	diabetes mellitus (is_marker_for)	HGF ICAM1	1.15e-03	41	36	2	DOID:9351 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
NLYHHVCMCNNETPN	BICD2	536	Q8TD16
SHYQLQLCPGADCPM	ARIH2	221	O95376
ALASCCMQPHSEYSA	DISP1	111	Q96F81
CMQPHSEYSASLCPN	DISP1	116	Q96F81
PKPFHSNCMFDTCNC	MUC5B	641	Q9HC84
MCANSQQSPPLCHDY	MUC5B	1406	Q9HC84
CYPAPMTVSCQAHNF	RTN4RL1	31	Q86UN2
AECNPHCAELYTNQM	NPAT	461	Q14207
HESYNFNMKCPTPGC	KAT7	176	O95251
RMTYFCPHCQKENPQ	NEIL3	271	Q8TAT5
HNDYMCPATNQCTID	ESR1	216	P03372
QNMCLVYQPASDHSP	KALRN	2356	O60229
PDFCPQKCPNNMQYH	MUC5AC	331	P98088
QKCPNNMQYHECRSP	MUC5AC	336	P98088
YCSQIPNCDMSHGQD	HGF	376	P14210
CLHFNMTPNCQYRPQ	ARHGAP32	1491	A7KAX9
NHYTNQTDMPHCLLC	GPRC6A	551	Q5T6X5
MPVAPSNHCDNQCPH	OCR1	1	Q9BZK8
ETFCPMECPQNSHYE	FCGBP	2726	Q9Y6R7
NETFCPMECPQNSHY	FCGBP	3926	Q9Y6R7
PMECPQNSHYELCAD	FCGBP	3931	Q9Y6R7
CQMTFPYSSNLAPHV	HOXD11	41	P31277
CPQNPYCVCFMSHFN	MC4R	271	P32245
TPNAQYCQMRCTFHP	KLKB1	41	P03952
DEMTCQHCPYDQRPN	GRM7	556	Q14831
EDSQPMCYSNCPDGQ	ICAM1	86	P05362
VDSHYCPSCLENMPS	DCTN4	46	Q9UJW0
SSCPPSYQGSCNSNM	R3HDML	226	Q9H3Y0
STLQMYPTPNGHCAN	MTMR3	946	Q13615
YPTAVLQCCSPTHMD	HSF5	306	Q4G112
NPYRQLPCNCHGSMP	TRMT1L	506	Q7Z2T5
TSCNEMNPPLPSHCN	MDM2	306	Q00987
SYPSDHCQDNMWRCP	NAGPA	301	Q9UK23
PGIMYLNNDTCCNSD	ADAM17	491	P78536
PNMQLLCDECNVAYH	UHRF2	356	Q96PU4
NCPFFMSVNTQPLCH	TNFAIP3	391	P21580
ELPSYPCEMCNFSAN	ZNF518A	146	Q6AHZ1
PCMQDQEAYSHCLIS	TTLL6	821	Q8N841
YGMNVQQHPKCPECC	ZPBP	306	Q9BS86
NMHSNNKPFPCSECG	ZNF648	356	Q5T619
NHMPCPENLNGYCIH	TMEFF1	271	Q8IYR6
CYMNSILQCLCNAPH	USP8	786	P40818