Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsialic acid binding

SIGLEC12 SIGLEC14 SIGLEC5

7.61e-0625313GO:0033691
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH2 DYNC2H1

3.51e-0418312GO:0008569
GeneOntologyMolecularFunctionmonosaccharide binding

SIGLEC12 SIGLEC14 SIGLEC5

4.26e-0495313GO:0048029
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH2 DYNC2H1

8.60e-0428312GO:0051959
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH2 DYNC2H1

1.50e-0337312GO:0045505
GeneOntologyMolecularFunctionFAD binding

TXNRD1 CYB5R2

2.12e-0344312GO:0071949
GeneOntologyCellularComponentficolin-1-rich granule membrane

SIGLEC14 SIGLEC5 FCAR

1.10e-0461323GO:0101003
GeneOntologyCellularComponenttertiary granule membrane

SIGLEC14 SIGLEC5 FCAR

1.88e-0473323GO:0070821
MousePhenoabnormal eosinophil differentiation

SIGLEC14 SIGLEC5

1.84e-054252MP:0002443
MousePhenoabnormal granulocyte differentiation

SIGLEC14 SIGLEC5 NDST2

4.43e-0539253MP:0008111
DomainUncharacterised_TMEM39

TMEM39B TMEM39A

2.49e-062302IPR019397
DomainTmp39

TMEM39B TMEM39A

2.49e-062302PF10271
DomainDynein_heavy_dom-1

DNAH2 DYNC2H1

6.94e-058302IPR013594
DomainDHC_N1

DNAH2 DYNC2H1

6.94e-058302PF08385
DomainATPase_dyneun-rel_AAA

DNAH2 DYNC2H1

2.24e-0414302IPR011704
DomainDynein_heavy_chain_D4_dom

DNAH2 DYNC2H1

2.24e-0414302IPR024317
DomainDynein_HC_stalk

DNAH2 DYNC2H1

2.24e-0414302IPR024743
DomainDynein_heavy_dom-2

DNAH2 DYNC2H1

2.24e-0414302IPR013602
DomainDHC_N2

DNAH2 DYNC2H1

2.24e-0414302PF08393
DomainMT

DNAH2 DYNC2H1

2.24e-0414302PF12777
DomainAAA_8

DNAH2 DYNC2H1

2.24e-0414302PF12780
DomainAAA_5

DNAH2 DYNC2H1

2.24e-0414302PF07728
Domainig

SIGLEC12 SIGLEC14 SIGLEC5 FCAR

2.31e-04190304PF00047
DomainImmunoglobulin

SIGLEC12 SIGLEC14 SIGLEC5 FCAR

2.31e-04190304IPR013151
DomainDHC_fam

DNAH2 DYNC2H1

2.59e-0415302IPR026983
DomainDynein_heavy_dom

DNAH2 DYNC2H1

2.59e-0415302IPR004273
DomainDynein_heavy

DNAH2 DYNC2H1

2.59e-0415302PF03028
DomainIg-like_fold

SIGLEC12 SIGLEC14 SIGLEC5 FCAR PTPRH COL20A1

7.80e-04706306IPR013783
DomainFYVE

WDFY2 WDFY1

9.86e-0429302PF01363
DomainFYVE

WDFY2 WDFY1

9.86e-0429302SM00064
DomainZnf_FYVE-rel

WDFY2 WDFY1

1.36e-0334302IPR017455
DomainZnf_FYVE

WDFY2 WDFY1

1.69e-0338302IPR000306
DomainZF_FYVE

WDFY2 WDFY1

1.87e-0340302PS50178
DomainV-set

SIGLEC12 SIGLEC14 SIGLEC5

3.14e-03184303PF07686
Domain-

SIGLEC12 SIGLEC14 SIGLEC5 FCAR COL20A1

3.79e-036633052.60.40.10
DomainIg/MHC_CS

SIGLEC14 SIGLEC5

3.90e-0358302IPR003006
DomainIg_V-set

SIGLEC12 SIGLEC14 SIGLEC5

3.91e-03199303IPR013106
DomainIG_MHC

SIGLEC14 SIGLEC5

4.17e-0360302PS00290
DomainIG

SIGLEC12 SIGLEC14 SIGLEC5 FCAR

4.39e-03421304SM00409
DomainIg_sub

SIGLEC12 SIGLEC14 SIGLEC5 FCAR

4.39e-03421304IPR003599
DomainIGc2

SIGLEC12 SIGLEC14 SIGLEC5

6.21e-03235303SM00408
DomainIg_sub2

SIGLEC12 SIGLEC14 SIGLEC5

6.21e-03235303IPR003598
DomainIG_LIKE

SIGLEC12 SIGLEC14 SIGLEC5 FCAR

7.52e-03491304PS50835
DomainIg-like_dom

SIGLEC12 SIGLEC14 SIGLEC5 FCAR

8.18e-03503304IPR007110
DomainG-protein_beta_WD-40_rep

WDFY2 WDFY1

8.20e-0385302IPR020472
Pubmed

The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils.

SIGLEC12 SIGLEC14 SIGLEC5

2.47e-08732315048729
Pubmed

[Functions and molecular evolution of Siglecs, a family of sialic acid receptor proteins].

SIGLEC12 SIGLEC14 SIGLEC5

2.47e-08732318453149
Pubmed

Selective Response to Bacterial Infection by Regulating Siglec-E Expression.

SIGLEC12 SIGLEC14 SIGLEC5

1.16e-071132332889432
Pubmed

CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder.

SIGLEC12 SIGLEC14 SIGLEC5

2.01e-071332335921817
Pubmed

Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus.

SIGLEC14 SIGLEC5

8.20e-07232224799499
Pubmed

The conserved transmembrane protein TMEM-39 coordinates with COPII to promote collagen secretion and regulate ER stress response.

TMEM39B TMEM39A

8.20e-07232233524011
Pubmed

Immunomodulatory activity of extracellular Hsp70 mediated via paired receptors Siglec-5 and Siglec-14.

SIGLEC14 SIGLEC5

8.20e-07232226459514
Pubmed

Large-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanisms.

SIGLEC12 SIGLEC14 SIGLEC5

1.41e-062432315331780
Pubmed

A novel Siglec-F+ neutrophil subset in the mouse nasal mucosa exhibits an activated phenotype and is increased in an allergic rhinitis model.

SIGLEC14 SIGLEC5

2.46e-06332232247614
Pubmed

Discovery of Siglec-14, a novel sialic acid receptor undergoing concerted evolution with Siglec-5 in primates.

SIGLEC14 SIGLEC5

2.46e-06332217012248
Pubmed

Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls.

SIGLEC14 SIGLEC5

2.46e-06332232134149
Pubmed

Siglec-F is induced by granulocyte-macrophage colony-stimulating factor and enhances interleukin-4-induced expression of arginase-1 in mouse macrophages.

SIGLEC14 SIGLEC5

2.46e-06332231520477
Pubmed

Antiallergic effect of anti-Siglec-F through reduction of eosinophilic inflammation in murine allergic rhinitis.

SIGLEC14 SIGLEC5

2.46e-06332223710953
Pubmed

Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling.

SIGLEC14 SIGLEC5

2.46e-06332219783675
Pubmed

Cloning and characterization of a novel mouse Siglec, mSiglec-F: differential evolution of the mouse and human (CD33) Siglec-3-related gene clusters.

SIGLEC14 SIGLEC5

2.46e-06332211579105
Pubmed

Mast Cell-Specific Expression of Human Siglec-8 in Conditional Knock-in Mice.

SIGLEC14 SIGLEC5

2.46e-06332230577572
Pubmed

Siglec-F-dependent negative regulation of allergen-induced eosinophilia depends critically on the experimental model.

SIGLEC14 SIGLEC5

2.46e-06332224698729
Pubmed

Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis.

SIGLEC14 SIGLEC5

2.46e-06332225497369
Pubmed

Siglec-F is a novel intestinal M cell marker.

SIGLEC14 SIGLEC5

2.46e-06332227524237
Pubmed

Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity.

SIGLEC14 SIGLEC5

4.92e-06432217562860
Pubmed

Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils.

SIGLEC14 SIGLEC5

4.92e-06432217272508
Pubmed

Siglec-8 on human eosinophils and mast cells, and Siglec-F on murine eosinophils, are functionally related inhibitory receptors.

SIGLEC14 SIGLEC5

4.92e-06432219178537
Pubmed

Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration.

SIGLEC14 SIGLEC5

4.92e-06432233289969
Pubmed

Induction of Siglec-FhiCD101hi eosinophils in the lungs following murine hookworm Nippostrongylus brasiliensis infection.

SIGLEC14 SIGLEC5

4.92e-06432237251384
Pubmed

IL-17 mediates protective immunity against nasal infection with Bordetella pertussis by mobilizing neutrophils, especially Siglec-F+ neutrophils.

SIGLEC14 SIGLEC5

4.92e-06432233976385
Pubmed

Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs.

SIGLEC14 SIGLEC5

8.19e-06532220395633
Pubmed

Siglec-F-expressing neutrophils are essential for creating a profibrotic microenvironment in renal fibrosis.

SIGLEC14 SIGLEC5

8.19e-06532235482420
Pubmed

The prognostic impact of SIGLEC5-induced impairment of CD8+ T cell activation in sepsis.

SIGLEC12 SIGLEC5

8.19e-06532237890368
Pubmed

Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13.

SIGLEC14 SIGLEC5

8.19e-06532221040544
Pubmed

Molecular analysis of human Siglec-8 orthologs relevant to mouse eosinophils: identification of mouse orthologs of Siglec-5 (mSiglec-F) and Siglec-10 (mSiglec-G).

SIGLEC14 SIGLEC5

1.23e-05632214559209
Pubmed

Galactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissue.

SIGLEC14 SIGLEC5

1.23e-05632223880769
Pubmed

Mechanisms of Siglec-F-induced eosinophil apoptosis: a role for caspases but not for SHP-1, Src kinases, NADPH oxidase or reactive oxygen.

SIGLEC14 SIGLEC5

1.72e-05732223840825
Pubmed

Sialyltransferase ST3Gal-III regulates Siglec-F ligand formation and eosinophilic lung inflammation in mice.

SIGLEC14 SIGLEC5

1.72e-05732223677475
Pubmed

Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1.

SIGLEC12 SIGLEC5

2.29e-05832225187624
Pubmed

Lectin galactoside-binding soluble 3 binding protein (LGALS3BP) is a tumor-associated immunomodulatory ligand for CD33-related Siglecs.

SIGLEC12 SIGLEC5

3.67e-051032225320078
Pubmed

A mouse knockout library for secreted and transmembrane proteins.

TSPAN12 SIGLEC12 SIGLEC14 SIGLEC5 PLA2G15

5.94e-0546032520562862
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH2 DYNC2H1

7.41e-05143229373155
Pubmed

Small intestinal resident eosinophils maintain gut homeostasis following microbial colonization.

SIGLEC14 SIGLEC5

1.11e-041732235709757
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

TSPAN12 SIGLEC12 SIGLEC14 NTNG2 CCL26 PLA2G15

2.45e-0498532612975309
Pubmed

A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting.

SIGLEC14 SIGLEC5

3.28e-042932233567267
Pubmed

Genome-wide association study of selenium concentrations.

TXNRD1 DYNC2H1

4.79e-043532225343990
Pubmed

Histone deacetylase 3 controls lung alveolar macrophage development and homeostasis.

SIGLEC14 SIGLEC5

5.35e-043732232732898
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

DNAH2 DYNC2H1

8.64e-04473228812413
Cytoband19q13.4

SIGLEC12 SIGLEC14 PTPRH

2.35e-057932319q13.4
CytobandEnsembl 112 genes in cytogenetic band chr19q13

SIGLEC12 SIGLEC14 SIGLEC5 FCAR PTPRH

1.32e-031192325chr19q13
GeneFamilyCD molecules|C2-set domain containing|Sialic acid binding Ig like lectins

SIGLEC12 SIGLEC14 SIGLEC5

7.48e-0628253745
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

WDFY2 WDFY1

8.33e-043125281
GeneFamilyAdenosine receptors|V-set domain containing

SIGLEC12 SIGLEC14 SIGLEC5

1.43e-03163253590
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SIGLEC12 SIGLEC14 FCAR NDST2

5.13e-0616032408696d93ff42a1beca23c70ab3e0d082cfff4aa7
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SIGLEC12 SIGLEC5 FIG4 PLA2G15

7.81e-061783240b398656f26c4061b11ccf98908d0e2e1367585a
ToppCellmild_COVID-19_(asymptomatic)-Neutrophil|World / disease group, cell group and cell class (v2)

SIGLEC14 SLC25A44 CERS4

1.45e-0566323e71738a3a84be93053d1ed20d030e4c606f8f402
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_Inf._Macrophages|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

DNAH2 FCAR CYB5R2

1.71e-0415132388f7498f29e43441e0982f9f97ea563edf2835a4
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC25A44 NTNG2 NDST2

2.14e-04163323953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellfacs-Heart-LV-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIGLEC5 MPP4 COL20A1

2.22e-04165323af59a095ecc6758abc13d763c00e44447c488167
ToppCellfacs-Heart-LV-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIGLEC5 MPP4 COL20A1

2.22e-0416532384eca6a0f5e996b6955ae79fa102af239098fe8f
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SIGLEC14 SIGLEC5 FCAR

2.51e-04172323cf46810dd1072b6f2171e5d9530351ddc79a055b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SIGLEC5 FCAR NDST2

2.51e-04172323ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCellwk_08-11-Mesenchymal-Fibroblast-Airway_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

JMJD7 CCL26 NDST2

2.55e-04173323b23b408acc29a667cce104429afef1a6cf2720a5
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS10 JMJD7 SZT2

2.78e-0417832309d2687e0d79f12e90af35fc1c0453d249cf2d19
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

SIGLEC5 NTNG2 FCAR

2.82e-04179323cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCellwk_15-18-Hematologic-Myeloid-APOE+_Mac2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SIGLEC12 PLA2G15 NDST2

2.87e-04180323c630a121aedd09a51ea18cc6e8552eb979e5b555
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

APBB2 DYNC2H1 WDFY2

2.96e-041823235f513bbb7125956eb528e3120de3fd776770a7c3
ToppCellLPS_only-Myeloid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TXNRD1 SIGLEC5 FCAR

2.96e-04182323666ac86ee5f6fa9241ae8d80340743707e54b278
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

APBB2 DYNC2H1 WDFY2

3.01e-041833232f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

APBB2 DYNC2H1 WDFY2

3.01e-041833232e831a4d99c6f983793df71c0994124c943c6da9
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIGLEC5 COL20A1 GEMIN8

3.06e-04184323a7399a72f065d68800e3e0b2031d9894e0cc0ba4
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-naive_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIGLEC5 TMEM39A WDFY1

3.11e-041853233f1aa91efae2d00320d126087cce1431ad5f26ea
ToppCellwk_15-18-Hematologic-Myeloid-Myelocyte-like|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SIGLEC14 SIGLEC5 FCAR

3.11e-0418532392b9ec18ff7c53a52b87e2c2012d0b719a7ad20a
ToppCellwk_08-11-Hematologic-Myeloid-S100A12-lo_cla._mono.|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SIGLEC12 SIGLEC5 FCAR

3.16e-04186323be50f5c7f32b3126442ebff1e7d38aa78b6e4e71
ToppCellcellseq-Immune-Hematopoietic-Granulocytic-Neutrophil|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SIGLEC5 NTNG2 FCAR

3.31e-04189323fedab592be1d6520325b8c1b659b0a4dc3f4fe4d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

APBB2 DYNC2H1 WDFY2

3.31e-04189323977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SIGLEC12 SIGLEC5 PLA2G15

3.31e-04189323a59025e82fabd9d60e2438dee85b2644478cc7c8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

APBB2 DYNC2H1 WDFY2

3.31e-041893237eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

APBB2 DYNC2H1 WDFY2

3.31e-04189323975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellBL-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TSPAN12 ALDH3B2 PTPRH

3.36e-04190323f2abe4bc28e934287e2dcd7b9399d5af78c5c8cf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

APBB2 DYNC2H1 WDFY2

3.36e-04190323e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCelldroplet-Marrow-BM-1m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIGLEC5 TMEM39A WDFY1

3.41e-041913238e8bc200524a44ebe132f823ab7c15dac65d4952
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIGLEC5 TMEM39A WDFY1

3.41e-041913234187f31ec399b4c7c3608e94e3c32b7a54b1c3d4
ToppCellPSB-critical-LOC-Myeloid-Neutrophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SIGLEC14 SIGLEC5 FCAR

3.46e-041923238dbdaa6a81767a866fb856f99ae35f9ee8064106
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SIGLEC5 FCAR PLA2G15

3.46e-04192323181d22fbb98a619a7f302c0f6623cee94c49a253
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-parabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 ALDH3B2 CYB5R2

3.52e-0419332355eab7d2574e9cc2ed8f08e0a7ca7cbf90fb5818
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SIGLEC14 FCAR NDST2

3.52e-04193323d9bb77214bb92e8392cf74e3bfdf177a96fd71ea
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SIGLEC14 SIGLEC5 FCAR

3.52e-04193323db26b79dfe9c48388f6b64dceb21073d104ab504
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

APBB2 DYNC2H1 WDFY2

3.62e-04195323a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SIGLEC14 SIGLEC5 FCAR

3.68e-041963234354ee481053e7b02e8c0bb16ea4377566ef2b53
ToppCelldistal-Hematologic-OLR1+_Classical_Monocyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SIGLEC14 FCAR NDST2

3.68e-0419632380fc5b9e04ead0b38304dccbe39f66575e2bf203
ToppCelldroplet-Tongue-nan-3m-Epithelial-parabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 ALDH3B2 CYB5R2

3.68e-04196323159061fd0961b2cfb5941d403acc5b395dd0d3a0
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SIGLEC12 SIGLEC14 FCAR

3.68e-041963239ae9cf69079b8a786e775c3db5cd4c593513f698
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SIGLEC12 SIGLEC5 PLA2G15

3.68e-04196323eb7d6bbfb766cdeaf5fe0f0bb66a5f491fd5ef26
ToppCelldistal-Hematologic-OLR1+_Classical_Monocyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SIGLEC14 FCAR NDST2

3.68e-041963233f57216dbc9ef28fca09bbb8805f7c15b03b99e8
ToppCellproximal-Hematologic-Alveolar_Macrophage-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SIGLEC12 SIGLEC5 PLA2G15

3.79e-04198323a5deecd8809bc5b38ffda02143598ad0145e2559
ToppCellproximal-Hematologic-Alveolar_Macrophage|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SIGLEC12 SIGLEC5 PLA2G15

3.79e-04198323ec0092ef6207e788e2c20ddf007a2f6f6e351d0b
ToppCelldistal-2-Hematologic-OLR1+_Classical_Monocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SIGLEC14 FCAR NDST2

3.79e-0419832343179d92e45b14f6f3d63949a9d88c2c7531f7d1
ToppCellproximal-3-Hematologic-Alveolar_Macrophage|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SIGLEC12 SIGLEC5 PLA2G15

3.79e-04198323a5daf11bf7fe614be9f4a0fc6a4b37b5dce2f6fc
ToppCelldistal-Hematologic-Alveolar_Macrophage-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SIGLEC12 SIGLEC5 PLA2G15

3.85e-041993232918967da22602404c767d948fed6c4754e53518
Diseasesialic acid-binding Ig-like lectin 6 measurement

SIGLEC12 SIGLEC5

2.98e-058312EFO_0008285
Diseasedolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 measurement

SIGLEC14 SIGLEC5

4.78e-0510312EFO_0801544
Diseasesialic acid-binding Ig-like lectin 14 measurement

SIGLEC14 SIGLEC5

7.00e-0512312EFO_0008284
Diseaseselenium measurement

TXNRD1 DYNC2H1

4.26e-0429312EFO_0006331
Diseasecholesteryl ester 16:0 measurement

NTNG2 DYNC2H1

6.58e-0436312EFO_0010341
Diseasemonocyte count

SIGLEC14 SLC25A44 SIGLEC5 PTPRH SZT2 WDFY2

2.23e-031320316EFO_0005091
DiseaseUterine leiomyoma

DNAH2 TSPAN12

4.13e-0391312HP_0000131
Diseaseleprosy

SIGLEC5 NTNG2

5.25e-03103312EFO_0001054

Protein segments in the cluster

PeptideGeneStartEntry
PNQTLKPSLYWWYLL

CERS4

171

Q9HA82
YYWHIPTGTTQWERP

APBB2

306

Q92870
HYPPYTDWNQQLLRW

ALDH3B2

361

P48448
RDSLPPYSWHYAPWT

ADAMTS10

821

Q9H324
WYTLDRPPIGWKYSS

CYB5R2

211

Q6BCY4
TSWLLPYNYTWSPEK

PLA2G15

266

Q8NCC3
ATRPWYSHPVYARYW

GEMIN8

11

Q9NWZ8
WPALQKWSLPYFRAT

JMJD7

61

P0C870
PAHYLERSPAWWYPY

HMX3

106

A6NHT5
WYNRSPYLWSFPSNA

FCAR

196

P24071
KQREFWWSQPYQPHT

MPP4

311

Q96JB8
WQRYVPHPWKNEKYF

DYNC2H1

306

Q8NCM8
WTPPLGRVLHYWLTY

COL20A1

761

Q9P218
PTRRSYTYWWTPEVI

FIG4

626

Q92562
YTYWWTPEVIKHLPL

FIG4

631

Q92562
QYPRDWHLWYTNAAP

DNAH2

3756

Q9P225
YWQSITWSRYPSPLE

NTNG2

106

Q96CW9
RYLYHQRWLWSVPSG

SZT2

791

Q5T011
PGKWPWQVSLRVYSY

PRSS29P

76

A6NIE9
PWRSWYSSPPLYVYW

SIGLEC5

46

O15389
PPCVWWKATSYHYVR

TMEM151A

146

Q8N4L1
LTYIPNSAVWWPFYH

SLC25A44

191

Q96H78
PHYNWTASSPVYGSW

SIGLEC12

176

Q96PQ1
QYSHKPLPWTWVRSY

CCL26

36

Q9Y258
VYHSYFWPLEWTIPS

TXNRD1

551

Q16881
WLKRDSGQYWPSVYH

WDFY2

51

Q96P53
KTVWWYPYNHPASCT

TMEM39A

96

Q9NV64
YPIHTQLYEAWKSVW

NDST2

436

P52849
TNYGLPRYRWLTHAW

TSPAN12

136

O95859
PHSQLYVYWVQWASK

PTPRH

591

Q9HD43
YVYWVQWASKGHPRR

PTPRH

596

Q9HD43
PWRSWYSSPPLYVYW

SIGLEC14

46

Q08ET2
WLKRDSGQYWPSIYH

WDFY1

51

Q8IWB7
YINIYKTVWWYPPSH

TMEM39B

96

Q9GZU3