Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranslation activator activity

DAZ4 DAZ1 DAZ3 DAZ2

2.30e-0715744GO:0008494
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in cardiac muscle cell action potential

CACNA1C CACNA1D

1.35e-045742GO:0086007
GeneOntologyMolecularFunctionalpha-actinin binding

CACNA1C CACNA1D DAG1

2.04e-0431743GO:0051393
GeneOntologyBiologicalProcessfemale meiosis II

DAZ4 DAZ1 DAZ3 DAZ2

2.15e-096734GO:0007147
GeneOntologyBiologicalProcessmeiosis II

DAZ4 DAZ1 DAZ3 DAZ2

2.15e-096734GO:0007135
GeneOntologyBiologicalProcessmeiosis II cell cycle process

DAZ4 DAZ1 DAZ3 DAZ2

2.15e-096734GO:0061983
GeneOntologyBiologicalProcessoocyte maturation

TUT4 DAZ4 DAZ1 DAZ3 DAZ2

6.60e-0747735GO:0001556
GeneOntologyBiologicalProcessoocyte development

TUT4 KMT2B DAZ4 DAZ1 DAZ3 DAZ2

1.38e-0699736GO:0048599
GeneOntologyBiologicalProcessoocyte differentiation

TUT4 KMT2B DAZ4 DAZ1 DAZ3 DAZ2

1.74e-06103736GO:0009994
GeneOntologyBiologicalProcesspositive regulation of meiotic nuclear division

DAZ4 DAZ1 DAZ3 DAZ2

2.03e-0626734GO:0045836
GeneOntologyBiologicalProcesspositive regulation of translational initiation

DAZ4 DAZ1 DAZ3 DAZ2

3.21e-0629734GO:0045948
GeneOntologyBiologicalProcess3'-UTR-mediated mRNA stabilization

DAZ4 DAZ1 DAZ3 DAZ2

4.23e-0631734GO:0070935
GeneOntologyBiologicalProcessneuromuscular junction development

MYCBP2 PPFIBP2 PPFIBP1 FARP1 FGFR2

4.23e-0668735GO:0007528
GeneOntologyBiologicalProcesspositive regulation of meiotic cell cycle

DAZ4 DAZ1 DAZ3 DAZ2

8.73e-0637734GO:0051446
GeneOntologyBiologicalProcessnegative regulation of catabolic process

PHF20L1 MYCBP2 DAZ4 KLHL40 DAZ1 DAZ3 DAZ2 MDM4 PINK1

1.63e-05418739GO:0009895
GeneOntologyBiologicalProcessoogenesis

TUT4 KMT2B DAZ4 DAZ1 DAZ3 DAZ2

1.91e-05156736GO:0048477
GeneOntologyBiologicalProcessregulation of meiotic nuclear division

DAZ4 DAZ1 DAZ3 DAZ2

1.93e-0545734GO:0040020
GeneOntologyBiologicalProcessregulation of nuclear division

DAZ4 APC DAZ1 FGFR2 DAZ3 DAZ2

3.30e-05172736GO:0051783
GeneOntologyBiologicalProcesspositive regulation of organelle organization

DOC2A DAZ4 APC DAZ1 DAZ3 DAZ2 FERMT2 MAPKAPK5 PLK4 PINK1

3.31e-055747310GO:0010638
GeneOntologyBiologicalProcessfemale meiotic nuclear division

DAZ4 DAZ1 DAZ3 DAZ2

3.44e-0552734GO:0007143
GeneOntologyBiologicalProcessregulation of catabolic process

TUT4 THRA PHF20L1 MYCBP2 DAZ4 KLHL40 APC DAZ1 PRKAG2 DAZ3 DAZ2 MDM4 MEFV PINK1

1.09e-0412527314GO:0009894
GeneOntologyBiologicalProcessregulation of cell cycle

BRINP3 ZNF274 DAZ4 BTN2A3P APC MRGPRX3 YY1AP1 DAZ1 FGFR2 DAZ3 DAZ2 MDM4 BIRC6 PLK4

1.12e-0412567314GO:0051726
GeneOntologyBiologicalProcessretrograde trans-synaptic signaling by trans-synaptic protein complex

FARP1 DAG1

1.23e-045732GO:0098942
GeneOntologyBiologicalProcesspositive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

CACNA1C CACNA1D

1.23e-045732GO:1904879
GeneOntologyBiologicalProcessfemale gamete generation

TUT4 KMT2B DAZ4 DAZ1 DAZ3 DAZ2

1.39e-04223736GO:0007292
GeneOntologyBiologicalProcesspositive regulation of nuclear division

DAZ4 DAZ1 DAZ3 DAZ2

1.45e-0475734GO:0051785
GeneOntologyBiologicalProcessmRNA stabilization

DAZ4 DAZ1 DAZ3 DAZ2

1.61e-0477734GO:0048255
GeneOntologyBiologicalProcesspositive regulation of translation

DAZ4 DAZ1 DAZ3 DAZ2 PINK1

1.98e-04151735GO:0045727
GeneOntologyBiologicalProcessregulation of meiotic cell cycle

DAZ4 DAZ1 DAZ3 DAZ2

2.05e-0482734GO:0051445
GeneOntologyBiologicalProcessregulation of organelle organization

DOC2A MYCBP2 PIK3R1 DAZ4 TRPM2 APC DAZ1 FGFR2 DAZ3 DAZ2 FERMT2 MAPKAPK5 PLK4 PINK1

2.25e-0413427314GO:0033043
GeneOntologyBiologicalProcessanatomical structure maturation

TUT4 DAZ4 DAG1 DAZ1 DAZ3 SLFN14 DAZ2

2.55e-04354737GO:0071695
GeneOntologyBiologicalProcessnegative regulation of mRNA catabolic process

DAZ4 DAZ1 DAZ3 DAZ2

2.57e-0487734GO:1902373
GeneOntologyBiologicalProcessregulation of reproductive process

HPGDS DAZ4 APC DAZ1 DAZ3 DAZ2

2.63e-04251736GO:2000241
GeneOntologyBiologicalProcessRNA stabilization

DAZ4 DAZ1 DAZ3 DAZ2

2.69e-0488734GO:0043489
GeneOntologyBiologicalProcessregulation of translational initiation

DAZ4 DAZ1 DAZ3 DAZ2

3.06e-0491734GO:0006446
GeneOntologyBiologicalProcesscell maturation

TUT4 DAZ4 DAZ1 DAZ3 SLFN14 DAZ2

3.66e-04267736GO:0048469
GeneOntologyBiologicalProcessnegative regulation of RNA catabolic process

DAZ4 DAZ1 DAZ3 DAZ2

4.55e-04101734GO:1902369
GeneOntologyBiologicalProcesslung-associated mesenchyme development

DPPA4 FGFR2

5.46e-0410732GO:0060484
GeneOntologyBiologicalProcesspositive regulation of cell cycle

DAZ4 MRGPRX3 DAZ1 FGFR2 DAZ3 DAZ2 PLK4

5.88e-04407737GO:0045787
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

CACNA1C CACNA1D TRPM2

6.56e-0448733GO:0098703
GeneOntologyBiologicalProcesscalcium ion import into cytosol

CACNA1C CACNA1D TRPM2

6.56e-0448733GO:1902656
GeneOntologyBiologicalProcesstrans-synaptic signaling by trans-synaptic complex

FARP1 DAG1

6.66e-0411732GO:0099545
GeneOntologyBiologicalProcessnegative regulation of mRNA metabolic process

DAZ4 DAZ1 DAZ3 DAZ2

7.42e-04115734GO:1903312
GeneOntologyBiologicalProcessregulation of cell cycle process

DAZ4 BTN2A3P APC MRGPRX3 DAZ1 FGFR2 DAZ3 DAZ2 BIRC6 PLK4

7.57e-048457310GO:0010564
GeneOntologyBiologicalProcesspositive regulation of cell cycle process

DAZ4 MRGPRX3 DAZ1 DAZ3 DAZ2 PLK4

7.64e-04307736GO:0090068
GeneOntologyBiologicalProcesscellular response to manganese ion

HSP90B1 SLFN14

7.97e-0412732GO:0071287
GeneOntologyBiologicalProcesspositive regulation of reproductive process

DAZ4 DAZ1 DAZ3 DAZ2

8.17e-04118734GO:2000243
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

THRA MYCBP2 PIK3R1 FARP1 TRPM2 APC DAG1 FNBP1L FERMT2 PLK4 MEFV PINK1

8.94e-0411897312GO:0044087
GeneOntologyBiologicalProcessorganelle fission

DAZ4 APC DAZ1 FGFR2 DAZ3 DAZ2 PEX11A PINK1

9.09e-04571738GO:0048285
GeneOntologyBiologicalProcessdevelopmental maturation

TUT4 DAZ4 DAG1 DAZ1 DAZ3 SLFN14 DAZ2

9.17e-04439737GO:0021700
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

DOC2A PIK3R1 DAZ4 APC DAG1 DAZ1 FNBP1L DAZ3 DAZ2 FERMT2 MAPKAPK5 PLK4 PINK1

9.22e-0413667313GO:0051130
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

CACNA1C CACNA1D RAPGEF6 NLRP1 FGFR2 PRKAG2 FERMT2 MAPKAPK5 MEFV PREX2 PINK1

9.32e-0410287311GO:0043085
GeneOntologyBiologicalProcessregulation of filopodium assembly

PIK3R1 TRPM2 FNBP1L

1.09e-0357733GO:0051489
GeneOntologyBiologicalProcesspositive regulation of protein localization

CACNA1C CACNA1D PIK3R1 FARP1 TRPM2 APC FERMT2 PINK1

1.13e-03591738GO:1903829
GeneOntologyBiologicalProcessregulation of heart rate

CACNA1C CACNA1D PIK3R1 MDM4

1.14e-03129734GO:0002027
MousePhenoabnormal lateral ventricle morphology

CHL1 CACNA1C KIF6 MYCBP2 DAG1 FGFR2 MDM4 TRAPPC9

9.75e-07164668MP:0000823
DomainDUF4062

NWD2 TEP1

1.59e-052752PF13271
DomainDUF4062

NWD2 TEP1

1.59e-052752IPR025139
DomainCAC1F_C

CACNA1C CACNA1D

4.76e-053752IPR031688
DomainCAC1F_C

CACNA1C CACNA1D

4.76e-053752PF16885
DomainVDCC_L_a1su

CACNA1C CACNA1D

9.50e-054752IPR005446
DomainLiprin

PPFIBP2 PPFIBP1

2.36e-046752IPR029515
DomainVDCC_a1su_IQ

CACNA1C CACNA1D

3.30e-047752IPR014873
DomainGPHH

CACNA1C CACNA1D

3.30e-047752PF16905
DomainGPHH_dom

CACNA1C CACNA1D

3.30e-047752IPR031649
DomainCa_chan_IQ

CACNA1C CACNA1D

3.30e-047752SM01062
DomainCa_chan_IQ

CACNA1C CACNA1D

3.30e-047752PF08763
DomainVDCCAlpha1

CACNA1C CACNA1D

7.01e-0410752IPR002077
DomainRRM_1

DAZ4 RNPC3 DAZ1 DAZ3 DAZ2

1.50e-03208755PF00076
DomainRRM

DAZ4 RNPC3 DAZ1 DAZ3 DAZ2

1.80e-03217755SM00360
DomainDH_1

PLEKHG6 FARP1 PREX2

2.08e-0363753PS00741
DomainRRM_dom

DAZ4 RNPC3 DAZ1 DAZ3 DAZ2

2.20e-03227755IPR000504
DomainRRM

DAZ4 RNPC3 DAZ1 DAZ3 DAZ2

2.32e-03230755PS50102
DomainRhoGEF

PLEKHG6 FARP1 PREX2

2.58e-0368753SM00325
DomainRhoGEF

PLEKHG6 FARP1 PREX2

2.81e-0370753PF00621
DomainDH_2

PLEKHG6 FARP1 PREX2

2.81e-0370753PS50010
DomainDH-domain

PLEKHG6 FARP1 PREX2

2.92e-0371753IPR000219
Domain-

PLEKHG6 FARP1 PREX2

2.92e-03717531.20.900.10
Domain-

DAZ4 RNPC3 DAZ1 DAZ3 DAZ2

3.00e-032447553.30.70.330
DomainDAPIN

NLRP1 MEFV

3.49e-0322752PS50824
DomainPYRIN

NLRP1 MEFV

3.49e-0322752PF02758
DomainDAPIN

NLRP1 MEFV

3.49e-0322752IPR004020
DomainPYRIN

NLRP1 MEFV

3.49e-0322752SM01289
DomainNucleotide-bd_a/b_plait

DAZ4 RNPC3 DAZ1 DAZ3 DAZ2

3.80e-03258755IPR012677
DomainNACHT

NLRP1 TEP1

3.81e-0323752PS50837
DomainNACHT_NTPase

NLRP1 TEP1

3.81e-0323752IPR007111
DomainTUDOR

PHF20L1 MTF2

5.23e-0327752SM00333
DomainTudor

PHF20L1 MTF2

6.44e-0330752IPR002999
DomainZF_PHD_1

KMT2B PHF20L1 MTF2

6.80e-0396753PS01359
DomainFERM_N

FARP1 FERMT2

7.75e-0333752PF09379
DomainFERM_N

FARP1 FERMT2

7.75e-0333752IPR018979
PathwayWP_OVARIAN_INFERTILITY

DAZ4 DAZ1 DAZ3 DAZ2

1.60e-0535624MM15948
Pubmed

Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene.

DAZ4 DAZ1 DAZ3 DAZ2

1.99e-1147547670487
Pubmed

Male infertility, genetic analysis of the DAZ genes on the human Y chromosome and genetic analysis of DNA repair.

DAZ4 DAZ1 DAZ3 DAZ2

1.99e-11475411694340
Pubmed

The human DAZ genes, a putative male infertility factor on the Y chromosome, are highly polymorphic in the DAZ repeat regions.

DAZ4 DAZ1 DAZ3 DAZ2

1.99e-1147549321470
Pubmed

Polymorphic expression of DAZ proteins in the human testis.

DAZ4 DAZ1 DAZ3 DAZ2

1.99e-11475419223287
Pubmed

Impact of partial DAZ1/2 deletion and partial DAZ3/4 deletion on male infertility.

DAZ4 DAZ1 DAZ3 DAZ2

1.99e-11475426232607
Pubmed

[Microdeletion of chromosome Y in male infertility: role of the DAZ gene].

DAZ4 DAZ1 DAZ3 DAZ2

1.99e-11475411688365
Pubmed

Polymorphic DAZ gene family in polymorphic structure of AZFc locus: Artwork or functional for human spermatogenesis?

DAZ4 DAZ1 DAZ3 DAZ2

1.99e-11475412752250
Pubmed

A novel approach for the analysis of DAZ gene copy number in severely idiopathic infertile men.

DAZ4 DAZ1 DAZ3 DAZ2

1.99e-11475411883873
Pubmed

Partial DAZ deletions in a family with five infertile brothers.

DAZ4 DAZ1 DAZ3 DAZ2

1.99e-11475412801575
Pubmed

Analysis of the DAZ gene family in cryptorchidism and idiopathic male infertility.

DAZ4 DAZ1 DAZ3 DAZ2

1.99e-11475415066457
Pubmed

Male infertility caused by a de novo partial deletion of the DAZ cluster on the Y chromosome.

DAZ4 DAZ1 DAZ3 DAZ2

1.99e-11475411095434
Pubmed

Four DAZ genes in two clusters found in the AZFc region of the human Y chromosome.

DAZ4 DAZ1 DAZ3 DAZ2

1.99e-11475410936047
Pubmed

[Study on DAZ gene copy deletion in severe oligozoospermia sperm donor for ICSI].

DAZ4 DAZ1 DAZ3 DAZ2

1.99e-11475416963411
Pubmed

PRMT5 protects genomic integrity during global DNA demethylation in primordial germ cells and preimplantation embryos.

DAZ4 DAZ1 DAZ3 DAZ2 MDM4

8.03e-111475525457166
Pubmed

Connecting cis-elements and trans-factors with mechanisms of developmental regulation of mRNA translation in meiotic and haploid mammalian spermatogenic cells.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575423579190
Pubmed

The dazzle in germ cell differentiation.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575420008336
Pubmed

Isolation of a mouse homolog of the human DAZ (Deleted in Azoospermia) gene.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-1157548679003
Pubmed

AZFc partial deletions in Chilean men with severe spermatogenic failure.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575417416365
Pubmed

Retinoic acid regulates germ cell differentiation in mouse embryonic stem cells through a Smad-dependent pathway.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575422293198
Pubmed

Loss of oocytes in Dazl knockout mice results in maintained ovarian steroidogenic function but altered gonadotropin secretion in adult animals.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575411089564
Pubmed

A human DAZ transgene confers partial rescue of the mouse Dazl null phenotype.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575410393944
Pubmed

The human autosomal gene DAZLA: testis specificity and a candidate for male infertility.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-1157548968756
Pubmed

A SPGY copy homologous to the mouse gene Dazla and the Drosophila gene boule is autosomal and expressed only in the human male gonad.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-1157548968755
Pubmed

DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575430380414
Pubmed

Regulated Formation of an Amyloid-like Translational Repressor Governs Gametogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575426411291
Pubmed

Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575434985827
Pubmed

Expression profiling of the developing testis in wild-type and Dazl knockout mice.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575414648873
Pubmed

The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-1157548896558
Pubmed

Evolution of the DAZ gene family suggests that Y-linked DAZ plays little, or a limited, role in spermatogenesis but underlines a recent African origin for human populations.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-1157549700189
Pubmed

Kinked β-strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZL.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575422021443
Pubmed

The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-1157549288969
Pubmed

Co-culture of spermatogonial stem cells with sertoli cells in the presence of testosterone and FSH improved differentiation via up-regulation of post meiotic genes.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575423456578
Pubmed

In vivo and in vitro analysis of homodimerisation activity of the mouse Dazl1 protein.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575410903443
Pubmed

Gene sequence, localization, and evolutionary conservation of DAZLA, a candidate male sterility gene.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-1157549143498
Pubmed

Bisphenol A exposure modifies DNA methylation of imprint genes in mouse fetal germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575422699882
Pubmed

A murine homologue of the human DAZ gene is autosomal and expressed only in male and female gonads.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-1157548845845
Pubmed

DAZ family proteins exist throughout male germ cell development and transit from nucleus to cytoplasm at meiosis in humans and mice.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575411058556
Pubmed

Dazl promotes germ cell differentiation from embryonic stem cells.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575419783541
Pubmed

DAZL protein expression in mouse preimplantation embryo.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575417761180
Pubmed

Dazl functions in maintenance of pluripotency and genetic and epigenetic programs of differentiation in mouse primordial germ cells in vivo and in vitro.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575419468308
Pubmed

Partial rescue of the Dazl knockout mouse by the human DAZL gene.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575412200456
Pubmed

Nature of the spermatogenic arrest in Dazl -/- mice.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575411514340
Pubmed

Mouse Dazl and its novel splice variant functions in translational repression of target mRNAs in embryonic stem cells.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575423298641
Pubmed

DAZL is essential for stress granule formation implicated in germ cell survival upon heat stress.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575422223682
Pubmed

Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575423223451
Pubmed

Identification of target messenger RNA substrates for the murine deleted in azoospermia-like RNA-binding protein.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575411804965
Pubmed

Decreased oocyte DAZL expression in mice results in increased litter size by modulating follicle-stimulating hormone-induced follicular growth.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-11575421270429
Pubmed

Mouse autosomal homolog of DAZ, a candidate male sterility gene in humans, is expressed in male germ cells before and after puberty.

DAZ4 DAZ1 DAZ3 DAZ2

9.95e-1157548661148
Pubmed

Upstream open reading frames control PLK4 translation and centriole duplication in primordial germ cells.

DAZ4 DAZ1 DAZ3 DAZ2 PLK4

1.20e-101575535772791
Pubmed

DAZL binds to the transcripts of several Tssk genes in germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675418452650
Pubmed

A developmental stage-specific switch from DAZL to BOLL occurs during fetal oogenesis in humans, but not mice.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675424086306
Pubmed

DAZL binds to 3'UTR of Tex19.1 mRNAs and regulates Tex19.1 expression.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675419247806
Pubmed

DAZL is a master translational regulator of murine spermatogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675431355046
Pubmed

Aged mouse ovaries possess rare premeiotic germ cells that can generate oocytes following transplantation into a young host environment.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675420157580
Pubmed

Mono-butyl phthalate-induced mouse testis injury is associated with oxidative stress and down-regulated expression of Sox9 and Dazl.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675428496037
Pubmed

DAZL regulates Tet1 translation in murine embryonic stem cells.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675426077710
Pubmed

Translation of the synaptonemal complex component Sycp3 is enhanced in vivo by the germ cell specific regulator Dazl.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675417526644
Pubmed

The mouse male germ cell-specific gene Tpx-1: molecular structure, mode of expression in spermatogenesis, and sequence similarity to two non-mammalian genes.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-1067541638086
Pubmed

Spermatogenesis in testes of Dazl null mice after transplantation of wild-type germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675414611632
Pubmed

Expression profiles of the DAZ gene family in human testis with and without spermatogenic failure.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675415066460
Pubmed

The fate of granulosa cells following premature oocyte loss and the development of ovarian cancers.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675423417416
Pubmed

The RNA-binding protein DAZL functions as repressor and activator of mRNA translation during oocyte maturation.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675432170089
Pubmed

Dazl binds in vivo to specific transcripts and can regulate the pre-meiotic translation of Mvh in germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675416278232
Pubmed

A gene trap mutation of a murine homolog of the Drosophila stem cell factor Pumilio results in smaller testes but does not affect litter size or fertility.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675417219433
Pubmed

The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675416001084
Pubmed

Cracd Marks the First Wave of Meiosis during Spermatogenesis and Is Mis-Expressed in Azoospermia Mice.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675432962040
Pubmed

Genetic mapping of a male germ cell-expressed gene Tpx-2 to mouse chromosome 17.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-1067541869307
Pubmed

A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675411390979
Pubmed

BOULE, a Deleted in Azoospermia Homolog, Is Recruited to Stress Granules in the Mouse Male Germ Cells.

DAZ4 DAZ1 DAZ3 DAZ2

2.98e-10675427632217
Pubmed

Identification of a novel gene, DZIP (DAZ-interacting protein), that encodes a protein that interacts with DAZ (deleted in azoospermia) and is expressed in embryonic stem cells and germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

6.95e-10775415081113
Pubmed

Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal mice.

DAZ4 DAZ1 DAZ3 DAZ2

6.95e-10775422699423
Pubmed

Characterization of the mouse Dazap1 gene encoding an RNA-binding protein that interacts with infertility factors DAZ and DAZL.

DAZ4 DAZ1 DAZ3 DAZ2

6.95e-10775411604102
Pubmed

Dazl can bind to dynein motor complex and may play a role in transport of specific mRNAs.

DAZ4 DAZ1 DAZ3 DAZ2

6.95e-10775416946704
Pubmed

Identification of two novel proteins that interact with germ-cell-specific RNA-binding proteins DAZ and DAZL1.

DAZ4 DAZ1 DAZ3 DAZ2

6.95e-10775410857750
Pubmed

The RNA-binding specificity of the mouse Dazl protein.

DAZ4 DAZ1 DAZ3 DAZ2

6.95e-10775411410654
Pubmed

The Dazh gene is expressed in male and female embryonic gonads before germ cell sex differentiation.

DAZ4 DAZ1 DAZ3 DAZ2

6.95e-1077549588208
Pubmed

DAZL and CPEB1 regulate mRNA translation synergistically during oocyte maturation.

DAZ4 DAZ1 DAZ3 DAZ2

6.95e-10775426826184
Pubmed

Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.

DAZ4 DAZ1 DAZ3 DAZ2

1.39e-09875423204224
Pubmed

Requirement of the 3'-UTR-dependent suppression of DAZL in oocytes for pre-implantation mouse development.

DAZ4 DAZ1 DAZ3 DAZ2

1.39e-09875429883445
Pubmed

A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection.

DAZ4 DAZ1 DAZ3 DAZ2

1.39e-09875410823932
Pubmed

A preliminary report on the implication of RT-PCR detection of DAZ, RBMY1, USP9Y and Protamine-2 mRNA in testicular biopsy samples from azoospermic men.

DAZ4 DAZ1 DAZ3 DAZ2

1.39e-09875411869379
Pubmed

Fanconi anemia complementation group C is required for proliferation of murine primordial germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

1.39e-09875410951504
Pubmed

Mouse dead end1 acts with Nanos2 and Nanos3 to regulate testicular teratoma incidence.

DAZ4 DAZ1 DAZ3 DAZ2

1.39e-09875432339196
Pubmed

Single-cell transcriptomics reveal temporal dynamics of critical regulators of germ cell fate during mouse sex determination.

DAZ4 DAZ1 DAZ3 DAZ2

1.39e-09875433749946
Pubmed

Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.

DAZ4 DAZ1 DAZ3 DAZ2

1.39e-09875422621333
Pubmed

DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors.

DAZ4 DAZ1 DAZ3 DAZ2

1.39e-09875432686646
Pubmed

Dazl deficiency leads to embryonic arrest of germ cell development in XY C57BL/6 mice.

DAZ4 DAZ1 DAZ3 DAZ2

2.49e-09975416310179
Pubmed

A Gene Regulatory Program for Meiotic Prophase in the Fetal Ovary.

DAZ4 DAZ1 DAZ3 DAZ2

2.49e-09975426378784
Pubmed

Embryoid bodies from mouse stem cells express oxytocin receptor, Oct-4 and DAZL.

DAZ4 DAZ1 DAZ3 DAZ2

2.49e-09975419695304
Pubmed

The epigenetic modifications and the anterior to posterior characterization of meiotic entry during mouse oogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

2.49e-09975428235998
Pubmed

Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

2.49e-09975420159962
Pubmed

Prostaglandin D2 acts through the Dp2 receptor to influence male germ cell differentiation in the foetal mouse testis.

MTF2 HPGDS DAZ4 DAZ1 DAZ3 DAZ2

3.04e-095875625142465
Pubmed

Analysis of Uncharacterized mKiaa1211 Expression during Mouse Development and Cardiovascular Morphogenesis.

DAZ4 DAZ1 DAZ3 DAZ2

4.15e-091075431234534
Pubmed

Tesmin transcription is regulated differently during male and female meiosis.

DAZ4 DAZ1 DAZ3 DAZ2

4.15e-091075414648882
Pubmed

MAX controls meiotic entry in sexually undifferentiated germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

4.15e-091075438433229
Pubmed

SYCP3-like X-linked 2 is expressed in meiotic germ cells and interacts with synaptonemal complex central element protein 2 and histone acetyltransferase TIP60.

DAZ4 DAZ1 DAZ3 DAZ2

4.15e-091075423810942
Pubmed

The CDY-related gene family: coordinated evolution in copy number, expression profile and protein sequence.

DAZ4 DAZ1 DAZ3 DAZ2

4.15e-091075412837688
Pubmed

Mice with Y chromosome deletion and reduced Rbm genes on a heterozygous Dazl1 null background mimic a human azoospermic factor phenotype.

DAZ4 DAZ1 DAZ3 DAZ2

4.15e-091075410601091
Pubmed

Knockout mouse model and gametogenic failure.

DAZ4 DAZ1 DAZ3 DAZ2

4.15e-09107549922113
Pubmed

NANOS2 suppresses the cell cycle by repressing mTORC1 activators in embryonic male germ cells.

DAZ4 DAZ1 DAZ3 DAZ2

6.51e-091175434401671
CytobandYq11.223

DAZ4 DAZ1 DAZ3 DAZ2

1.72e-0593754Yq11.223
Cytoband1p22.1

MTF2 FNBP1L

1.27e-03327521p22.1
CytobandEnsembl 112 genes in cytogenetic band chr1p22

MTF2 ZNF644 FNBP1L

1.50e-03137753chr1p22
CytobandEnsembl 112 genes in cytogenetic band chrYq11

DAZ4 DAZ1 DAZ3 DAZ2

1.72e-03311754chrYq11
Cytoband4p14

TLR10 NWD2

2.17e-03427524p14
GeneFamilyRNA binding motif containing

DAZ4 RNPC3 DAZ1 DAZ3 DAZ2

5.51e-04213575725
GeneFamilyPyrin domain containing|Pyrin and HIN domain family

NLRP1 MEFV

2.80e-0325572994
GeneFamilyPHD finger proteins

KMT2B PHF20L1 MTF2

2.87e-039057388
GeneFamilyCalcium voltage-gated channel subunits

CACNA1C CACNA1D

3.02e-0326572253
CoexpressionTESAR_JAK_TARGETS_MOUSE_ES_D3_DN

DAZ4 DAZ1 DAZ3 DAZ2

3.01e-0812754MM742
CoexpressionSASAI_TARGETS_OF_CXCR6_AND_PTCH1_DN

DAZ4 DAZ1 DAZ3 DAZ2

3.01e-0812754MM781
CoexpressionWAGSCHAL_EHMT2_TARGETS_UP

DAZ4 DAZ1 DAZ3 DAZ2

5.25e-0723754MM1293
CoexpressionMATZUK_SPERMATOGONIA

DAZ4 DAZ1 DAZ3 DAZ2

1.83e-0631754MM765
CoexpressionCHEN_ETV5_TARGETS_TESTIS

DAZ4 DAZ1 DAZ3 DAZ2

2.38e-0633754MM701
CoexpressionMADAN_DPPA4_TARGETS

DPPA4 DAZ4 DAZ1 DAZ3 DAZ2

4.87e-0686755MM1312
CoexpressionGSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_UP

SF3B1 ST3GAL5 MYCBP2 PPFIBP2 NLRP1 PINK1

2.31e-05199756M4526
CoexpressionTONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP

HPGDS PPFIBP1 FARP1 DAG1 EBNA1BP2 FERMT2

2.59e-05203756M10184
CoexpressionMCCABE_BOUND_BY_HOXC6

MTF2 DAZ4 NOXRED1 DAZ1 FGFR2 DAZ3 DAZ2 FERMT2

5.19e-05461758M6376
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

CHL1 BDP1 CACNA1C TUT4 RAPGEF6 THRA ST3GAL5 MYCBP2 PPFIBP1 APC GRIK2 FNBP1L

6.73e-0511067512M39071
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_3DY_NEGATIVE

RAPGEF6 ZNF274 PHF20L1 MTF2 PIK3R1 PPFIBP1 HEATR1

8.16e-05363757M41103
ToppCellcontrol-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CHL1 LRIG3 PHF20L1 MYCBP2 PIK3R1 FGFR2 MDM4

4.58e-081997573d01f90ffd271ca00129192787e4921bdca7e01e
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BDP1 SF3B1 MYCBP2 PIK3R1 ZNF644 MDM4 BIRC6

4.74e-0820075712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 LRIG3 SCCPDH PPFIBP1 PREX2

1.01e-051707555d5f208682be21ed58320f5fc083a7898f8712da
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPATA17 CCDC198 PPFIBP1 FARP1 FGFR2

1.16e-05175755284fdc7a9d303636a637041846850d19d114861a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 DMGDH BTBD16 CCDC198 PPFIBP1

1.41e-05182755eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D CCDC198 PPFIBP1 FARP1 FGFR2

1.56e-05186755b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 DMGDH SCCPDH CCDC198 PPFIBP1

1.60e-05187755c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCellCOVID-19_Severe-HSPC|COVID-19_Severe / disease group, cell group and cell class

SCCPDH HPGDS DPPA4 PPFIBP1 PREX2

1.69e-0518975596015439971e2e5b8d6294ca5a6b873c7774e925
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CHL1 CACNA1C CACNA1D BRINP3 PREX2

1.73e-051907557986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 CCDC198 PPFIBP1 FARP1 FGFR2

1.77e-05191755d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D CCDC198 FARP1 FGFR2 FNBP1L

1.91e-051947555eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2|World / Primary Cells by Cluster

CHL1 BDP1 PIK3R1 PPFIBP1 APC

2.16e-05199755f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BDP1 PIK3R1 RNPC3 ZNF644 MDM4

2.16e-05199755f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_IV|World / Primary Cells by Cluster

CHL1 BDP1 PIK3R1 PPFIBP1 APC

2.16e-05199755e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCellControl-Control-Others-HSPC|Control / Disease, condition lineage and cell class

SCCPDH HPGDS DPPA4 PPFIBP1 FNBP1L

2.16e-05199755b71169be0d916b2ed139a3122d78bb154c71edb4
ToppCellNS-control-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CHL1 LRIG3 PHF20L1 MYCBP2 FGFR2

2.16e-0519975532bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCellcontrol-Epithelial-Secretory|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CHL1 LRIG3 PHF20L1 MYCBP2 FGFR2

2.16e-05199755262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

BDP1 CACNA1C CACNA1D MYCBP2 GRIK2

2.21e-0520075548d801219bc771d6c7e151dc88ca4c179988de85
ToppCellSigmoid-Dendritic_cell-cDC1|Dendritic_cell / Region, Cell class and subclass

TLR10 DPPA4 NLRP1 FERMT2 C2CD2

2.21e-0520075509deb831fc2c8a8867cc850f3aa094a5e48489ff
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH KLHL40 GRIK2 MEFV

1.14e-04148754dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCellfacs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KMT2B NLRP1 MAPKAPK5 MEFV

1.26e-04152754931c10245cde9b3290224cc1da46b2bf300b9ac2
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Pro-B|bone_marrow / Manually curated celltypes from each tissue

TLR10 DPPA4 PPFIBP1 FNBP1L

1.40e-04156754b093dbba6662e4fffc8aa577587b77f64ac44b56
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LVRN CACNA1D RNPC3 FERMT2

1.40e-041567544d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCellmild-Myeloid-Eosinophils|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SCCPDH HPGDS FGFR2 FNBP1L

1.65e-041637547c57d541a88e9afa079e95b8a6ecdea60a0c6aaa
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 KIF6 CCDC198 FARP1

1.69e-041647541cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

PPFIBP1 FARP1 FNBP1L FERMT2

1.94e-04170754e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C DCHS2 NWD2 PPFIBP2

1.94e-041707545570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellsevere-Myeloid-Eosinophils|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CACNA1D SCCPDH HPGDS FGFR2

1.94e-04170754863f0266d5837cdbc3e09a3fe6a99dd3e6261674
ToppCellcontrol-Myeloid-Eosinophils|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SCCPDH HPGDS FGFR2 FNBP1L

1.98e-0417175482f736c33ed96c0865618e8f8eb82a5487126bdc
ToppCellmild-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SCCPDH HPGDS FGFR2 FNBP1L

1.98e-041717545c8198182495bda7a826e9d80aa467f4eb1094ec
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Deuterosomal|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

DOC2A BTBD16 SPATA17 PLK4

1.98e-0417175452aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCell356C-Myeloid-Monocyte-CD16+_Monocyte|Monocyte / Donor, Lineage, Cell class and subclass (all cells)

THRA ALKBH2 PPFIBP1 FERMT2

2.03e-041727549dca1542145d88559527db7e0f6ad150df59ca2d
ToppCellHealthy_donor-HSPC|Healthy_donor / disease group, cell group and cell class (v2)

CACNA1C HPGDS DPPA4 FNBP1L

2.03e-04172754bc7549faadfc92c683c0e26bea380458706774b5
ToppCellmetastatic_Brain-Myeloid_cells-CD207+CD1a+_LCs|Myeloid_cells / Location, Cell class and cell subclass

TLR10 CHL1 HPGDS PPFIBP1

2.03e-0417275438d17e769fe8eac8b57b820490d4ddd969243ee7
ToppCellRV-11._Adipocyte|RV / Chamber and Cluster_Paper

LVRN NWD2 MYCBP2 C2CD2

2.31e-04178754278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

FARP1 GRIK2 FGFR2 FNBP1L

2.31e-0417875435a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCellsevere-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CACNA1D SCCPDH HPGDS FGFR2

2.41e-04180754ac03812b1409435c55d323a7516deeac82bd3509
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 DMGDH CCDC198 PPFIBP1

2.46e-041817549d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPATA17 CCDC198 PPFIBP1 FARP1

2.46e-041817546956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Deuterosomal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DOC2A BTBD16 SPATA17 PLK4

2.52e-04182754000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCellhealthy_donor-Myeloid-Monocytic-SC_&_Eosinophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

SCCPDH HPGDS DPPA4 FNBP1L

2.52e-041827546bd6c32c48fecd6d03ac8a09e405b3b99bdc12ae
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

LVRN NWD2 MYCBP2 C2CD2

2.57e-041837543f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCellCOVID-19_Severe-Hematopoietic_SC-HSPC|COVID-19_Severe / Disease group, lineage and cell class

HPGDS DPPA4 PPFIBP1 PREX2

2.57e-041837544146b1c0e5f76d25226745abfa28f77127a444fc
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCHS2 FARP1 DAG1 PLK4

2.57e-0418375491079a11685dd466bd27a0cf5afbf3734c08a05e
ToppCellCOVID-19_Severe-Hematopoietic_SC|COVID-19_Severe / Disease group, lineage and cell class

HPGDS DPPA4 PPFIBP1 PREX2

2.57e-0418375492aab7ce65aca17988bc2add4ff9fb8384e2c21b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 SCCPDH CCDC198 PPFIBP1

2.57e-0418375492fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellPBMC-Severe-Hematopoietic-HSPC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HPGDS DPPA4 PPFIBP1 PREX2

2.62e-04184754a6169613c6493b947a176493f542368bfa935dab
ToppCellPBMC-Severe-Hematopoietic-HSPC-HSPC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HPGDS DPPA4 PPFIBP1 PREX2

2.62e-0418475451d0447699e3b8f01abbde83f26b748bc9f3c723
ToppCellPBMC-Severe-Hematopoietic-HSPC-HSPC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HPGDS DPPA4 PPFIBP1 PREX2

2.62e-04184754f7b0bb45a9055ab34e98b251217f6ec38c75ca22
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUT4 MYCBP2 APC BIRC6

2.62e-041847541154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellcontrol-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SCCPDH HPGDS FGFR2 FNBP1L

2.62e-04184754fad517d047e8eaeaa5bd4f311d770880568dd13c
ToppCellCOVID-19_Moderate-HSPC|World / disease group, cell group and cell class

SCCPDH HPGDS DPPA4 PPFIBP1

2.62e-04184754ccc93babe1fcdeb66b78e1d8414357877a7c45bd
ToppCellPBMC-Severe-Hematopoietic-HSPC-HSPC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HPGDS DPPA4 PPFIBP1 PREX2

2.62e-04184754cc01c19180861f491a8dc16d60fabd1215fc4525
ToppCellPBMC-Severe-Hematopoietic-HSPC-HSPC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HPGDS DPPA4 PPFIBP1 PREX2

2.62e-04184754492c680f0769ba4e651d09c2e8e5d5d271ed08aa
ToppCellPBMC-Severe-Hematopoietic-HSPC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

HPGDS DPPA4 PPFIBP1 PREX2

2.62e-0418475426edbf84216538b80f1ffcc079ee6e385a71fbf9
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 BTBD16 DAG1 GRIK2

2.68e-041857543d1353dbcb60e2531ef67e1bd218b7bc4d7c7c9b
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 BTBD16 DAG1 GRIK2

2.68e-04185754995a8ddc3fd8e6879d8b5de8cbdefe232d34833b
ToppCellCOVID-19_Moderate-HSPC|COVID-19_Moderate / disease group, cell group and cell class

SCCPDH HPGDS DPPA4 PPFIBP1

2.68e-04185754cacc6ab5f26f6c803894567fb838ea06eaa7efe5
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPATA17 CCDC198 PPFIBP1 FARP1

2.73e-041867545c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CHL1 LRIG3 BRINP3 GRIK2

2.73e-041867547def03dd856b765bd3f493288641981c4f7fd26e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 NWD2 PIK3R1 PPFIBP1

2.73e-04186754bdbe290f81106a53c8c30a92fbb385597c62b2ac
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 NWD2 PIK3R1 PPFIBP1

2.79e-04187754f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIBP1 DAG1 FNBP1L PREX2

2.79e-041877543548a9914c2b2f5d805798ce22ab26eab6d03897
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 BTBD16 DAG1 GRIK2

2.79e-0418775416e55d802fc4e71878305e61ad03806aabd59537
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIBP1 DAG1 FNBP1L PREX2

2.79e-04187754f4de4b7af1fdfbd628b1f509c060c1079d2e5437
ToppCelldroplet-Limb_Muscle-nan-24m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 DMGDH DAG1 GRIK2

2.79e-04187754a0bd2b0ec9e73521c245037b1dd51ff8cf24cbf5
ToppCelldroplet-Limb_Muscle-nan-24m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 DMGDH DAG1 GRIK2

2.79e-04187754f2af79a20438108c814a73f9e24cd986d537237f
ToppCellControl-Endothelial-VE_Capillary_A|Control / Disease state, Lineage and Cell class

CHL1 PPFIBP1 FERMT2 PREX2

2.79e-0418775454d7588172ac145ff5045ad9771636729ca3f0ca
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Endothelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIBP1 DAG1 FNBP1L PREX2

2.79e-0418775481754e965848b718be20ee97ce072ce426938a69
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CACNA1C BRINP3 GRIK2 PRKAG2

2.85e-0418875474f7d216209cabdc96b2d46685b0ae017fdcc8fc
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 CCDC198 PPFIBP1 FARP1

2.85e-0418875463a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellCOVID-19_Severe-HSPC|World / disease group, cell group and cell class

HPGDS DPPA4 PPFIBP1 PREX2

2.90e-04189754555c0b13f1508b9e3712b36d77144e73e828bc76
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 NWD2 PIK3R1 PRKAG2

2.90e-04189754a75226616340045b581d08429d2e123e041dee55
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

LRIG3 GRIK2 FGFR2 FNBP1L

2.90e-0418975484d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CACNA1C BRINP3 GRIK2 PRKAG2

2.90e-04189754da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 SCCPDH PPFIBP2 PRKAG2

2.90e-04189754532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 NWD2 PIK3R1 PPFIBP1

2.90e-04189754c3df0e3c50af8f1cfb4d790e668bd7f42b276992
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

FARP1 GRIK2 FGFR2 FNBP1L

2.96e-04190754756bff697d30aec56c0ebfca94295f084a15bf37
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 TUT4 CCDC198 PPFIBP1

2.96e-04190754b855b8b7d3439023390ca44629c1a99f5d4c6801
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 NWD2 PIK3R1 PPFIBP1

2.96e-04190754d594da827e3c16644952b9589cc12b947ce36279
ToppCellpdx-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

DMGDH PLEKHG6 PPFIBP2 PRKAG2

2.96e-04190754b05db0de9b6ae01dd30074453f7de44f7397631e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 BTBD16 DAG1 GRIK2

2.96e-04190754ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CHL1 DCHS2 PPFIBP1 PREX2

2.96e-041907540a351609a72fd638c84b2435782e312ee6a33aac
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 NWD2 PIK3R1 PRKAG2

2.96e-0419075449e09cdb843b3d889a06a811aa5affae68b25a75
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 BTBD16 DAG1 GRIK2

2.96e-041907544971857eac9af17d66d673ed2ab7072639f60a10
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CACNA1C CACNA1D BRINP3 PREX2

3.02e-04191754fa380a8752de158974b2ae5e741573439719cc0d
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CACNA1C CACNA1D PIK3R1 PREX2

3.14e-041937549f69edc97b868d23998abc98928a2e89a885ef8a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 SCCPDH CCDC198 PPFIBP1

3.14e-041937540f2167eef8203a5659c8c72e4e77646003d64797
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHL1 SCCPDH PPFIBP1 GRIK2

3.14e-04193754d5930f7bd9b299f792212d40a3272a37adf64a82
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C CACNA1D PIK3R1 PREX2

3.14e-0419375499525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DMGDH CACNA1D CCDC198 FARP1

3.14e-0419375482e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DMGDH CACNA1D CCDC198 FARP1

3.14e-041937543866667dd221612589ae50f5c52f73a183a49ce6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DMGDH CCDC198 FARP1 FGFR2

3.21e-0419475493c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1D BRINP3 PIK3R1 PREX2

3.21e-0419475471d3c7448b1734de54187f902f65649f9283bd4c
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

APC FNBP1L MDM4 SENP5

3.21e-04194754b111d10c99d7ff7eb261cd7786cd9d9a549049b1
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

CACNA1C BRINP3 GRIK2 PRKAG2

3.21e-0419475489812fb164065041357bb37a3c2d87028ec3de4e
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSP90B1 HPGDS PIK3R1 APC

3.27e-04195754a1478021a3ed0e779716393124ca2a7770c433b7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC198 FARP1 FGFR2 FNBP1L

3.27e-041957546477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CHL1 FARP1 GRIK2 FGFR2

3.27e-04195754e7230a849ea31e6eef9bc6f5468938499450582d
ToppCellControl-Neu_4|Control / 5 Neutrophil clusters in COVID-19 patients

BDP1 HSP90B1 HEATR1 MGA

3.33e-04196754b8b7b54ca17a08fa775507bb22b1c7248ada8f40
Drugboron trichloride

DAZ4 DAZ1 DAZ3 DAZ2

1.62e-096754CID000025135
Drugdesmethylazelastine

DAZ4 DAZ1 DAZ3 DAZ2

1.92e-0716754CID000162558
Drug2-chlorodideoxyadenosine

HSP90B1 DAZ4 DAZ1 DAZ3 DAZ2

2.96e-0743755CID000072194
Drugdazmegrel

DAZ4 DAZ1 DAZ3 DAZ2

4.05e-0719754CID000053555
DrugYM 026

DAZ4 DAZ1 DAZ3 DAZ2

4.05e-0719754CID000004443
DrugAZFd

DAZ4 DAZ1 DAZ3 DAZ2

9.17e-0723754CID000196489
Drugdansylaziridine

DAZ4 DAZ1 DAZ3 DAZ2

9.17e-0723754CID000104008
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A

BRINP3 MTF2 PIK3R1 ZNF200 MGA PLK4 C2CD2

2.51e-061847572321_DN
DrugH-7 dihydrochloride; Down 200; 100uM; MCF7; HT_HG-U133A

BRINP3 ZNF274 MTF2 PIK3R1 ZNF200 MGA PLK4

3.00e-061897575936_DN
Drugd-gluconhydroximo-1,5-lactam

DAZ4 DAZ1 DAZ3 DAZ2

3.19e-0631754CID000003479
Drugikarugamycin; Down 200; 2uM; MCF7; HT_HG-U133A_EA

DOC2A PLEKHG6 PPFIBP1 APC PEX11A MDM4 PLK4

3.44e-06193757974_DN
DrugAminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A

DOC2A THRA ST3GAL5 FARP1 MDM4 TEP1 PREX2

3.68e-061957574748_DN
DrugCyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A

DOC2A TUT4 PLEKHG6 ST3GAL5 APC MDM4 SENP5

3.68e-061957573268_UP
DrugVistar

DAZ4 DAZ1 DAZ3 DAZ2

5.91e-0636754CID000040896
Drug3-bromo-7-nitroindazole

DAZ4 DAZ1 DAZ3 DAZ2

5.91e-0636754CID000001649
Drugmolybdenum disulfide

DAZ4 DAZ1 DAZ3 DAZ2

1.22e-0543754CID000014823
Drugpropham

DAZ4 DAZ1 DAZ3 DAZ2

1.33e-0544754CID000024685
DrugFPL 64176

CACNA1C CACNA1D APC

1.52e-0515753CID000003423
Drugridogrel

DAZ4 DAZ1 DAZ3 DAZ2

2.61e-0552754CID005362391
Drugazafagomine

DAZ4 DAZ1 DAZ3 DAZ2

3.76e-0557754CID011957435
DrugPergolide mesylate [66104-23-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A

DOC2A CACNA1D PHF20L1 PPFIBP1 FGFR2 PLK4

4.50e-051957567434_UP
Drug(+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; MCF7; HT_HG-U133A

CACNA1D PPFIBP1 FARP1 FGFR2 PLK4 PREX2

4.50e-051957564980_DN
DrugFolic acid [59-30-3]; Down 200; 9uM; MCF7; HT_HG-U133A

DOC2A APC FGFR2 PEX11A MDM4 SENP5

4.77e-051977562783_DN
DrugIsoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Down 200; 16.4uM; HL60; HT_HG-U133A

PIK3R1 PPFIBP1 APC NLRP1 FNBP1L MDM4

4.77e-051977562463_DN
DrugNoscapine [128-62-1]; Up 200; 9.6uM; MCF7; HT_HG-U133A

DOC2A BRINP3 ST3GAL5 PPFIBP2 APC PREX2

5.04e-051997562745_UP
DrugCefoxitin sodium salt [33564-30-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A

PHF20L1 ST3GAL5 FARP1 APC PLK4 TRAPPC9

5.19e-052007563477_DN
DrugNSC56408

DAZ4 DAZ1 DAZ3 DAZ2

5.24e-0562754CID000005604
DrugEGTA-AM

CACNA1C CACNA1D HSP90B1 NLRP1

5.24e-0562754CID000121907
DrugNSC-686960

CACNA1C CACNA1D

6.40e-054752CID000192816
DrugLinuron

DOC2A CACNA1C CACNA1D GRIK2 FGFR2

6.54e-05128755ctd:D008044
Drugkt S

DAZ4 DAZ1 DAZ3 DAZ2

6.71e-0566754CID006399216
Drugazelastine

DAZ4 DAZ1 DAZ3 DAZ2

1.05e-0474754CID000002267
DrugNilvadipine

CACNA1C CACNA1D

1.06e-045752DB06712
DrugNisoldipine

CACNA1C CACNA1D

1.06e-045752DB00401
DrugB 874-67

CACNA1C CACNA1D

1.06e-045752CID000195466
Drugmethyl beta-aminocrotonate

CACNA1C CACNA1D

1.06e-045752CID000084253
Drugnemadipine-A

CACNA1C CACNA1D

1.06e-045752CID002856102
Drugp11-13

DAZ4 DAZ1 DAZ3 DAZ2

1.11e-0475754CID000015759
Drugremifentanil

CACNA1C CACNA1D TRAPPC9

1.59e-0432753CID000060814
DrugCPU-23

CACNA1C CACNA1D

1.59e-046752CID003036051
Drugprocymidone

DOC2A CACNA1C CACNA1D HSP90B1 GRIK2

1.61e-04155755ctd:C035988
DiseaseMale sterility due to Y-chromosome deletions

DAZ4 DAZ1 DAZ3 DAZ2

2.39e-098734C2931163
DiseasePartial chromosome Y deletion

DAZ4 DAZ1 DAZ3 DAZ2

2.39e-098734C1507149
DiseaseAnemia, Macrocytic

THRA APC

6.04e-062732C0002886
DiseaseSpermatogenic Failure, Nonobstructive, Y-Linked

DAZ1 DAZ3 DAZ2

7.95e-0616733C1839071
DiseaseSPERMATOGENIC FAILURE, Y-LINKED, 2

DAZ1 DAZ3 DAZ2

7.95e-0616733415000
DiseaseSpermatogenic failure, Y-linked, 2

DAZ1 DAZ3 DAZ2

7.95e-0616733cv:C1839071
DiseaseGlioblastoma Multiforme

PIK3R1 APC GRIK2 MDM4 PINK1

8.43e-06111735C1621958
DiseaseManic Disorder

CACNA1C CACNA1D TRPM2 GRIK2

2.95e-0571734C0024713
DiseaseTimothy syndrome (implicated_via_orthology)

CACNA1C CACNA1D

3.61e-054732DOID:0060173 (implicated_via_orthology)
DiseaseManic

CACNA1C CACNA1D TRPM2 GRIK2

4.28e-0578734C0338831
DiseaseDepression, Bipolar

CACNA1C CACNA1D TRPM2 GRIK2

4.50e-0579734C0005587
Diseaseresponse to angiotensin receptor blocker

CACNA1D ST3GAL5 PRKAG2

5.62e-0530733EFO_0010735
Diseasehepatocellular carcinoma (is_implicated_in)

SF3B1 KMT2B APC FGFR2 TEP1

8.81e-05181735DOID:684 (is_implicated_in)
Diseaseimpulse control disorder

PRKAG2 MEFV

9.00e-056732MONDO_0001162
DiseasePsychotic Disorders

CACNA1C HPGDS TRPM2 FGFR2

1.17e-04101734C0033975
DiseaseBipolar Disorder

CACNA1C CACNA1D HSP90B1 HPGDS TRPM2 GRIK2 FGFR2

1.79e-04477737C0005586
DiseaseMalignant Neoplasms

SF3B1 PIK3R1 APC BIRC6

2.92e-04128734C0006826
DiseaseGastric cancer

APC FGFR2

3.27e-0411732cv:C0024623
DiseaseNeoplasm of stomach

APC FGFR2

3.27e-0411732cv:C0038356
Diseasepeptidyl-glycine alpha-amidating monooxygenase measurement

LVRN MYCBP2

3.27e-0411732EFO_0801871
DiseaseGASTRIC CANCER

APC FGFR2

3.27e-0411732613659
Diseaseendometrial carcinoma (is_implicated_in)

PIK3R1 APC

3.92e-0412732DOID:2871 (is_implicated_in)
DiseaseNonorganic psychosis

CACNA1C TRPM2 FGFR2

6.77e-0469733C0349204
Diseasestomach cancer (is_implicated_in)

APC FGFR2 TEP1

7.67e-0472733DOID:10534 (is_implicated_in)
DiseaseBenign neoplasm of stomach

APC FGFR2

8.02e-0417732C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

APC FGFR2

8.02e-0417732C0496905
DiseaseLimb Deformities, Congenital

CACNA1C FGFR2

8.02e-0417732C0206762
DiseaseCarcinoma in situ of stomach

APC FGFR2

8.02e-0417732C0154060
DiseaseMood Disorders

CACNA1C CACNA1D HPGDS GRIK2

8.13e-04168734C0525045
DiseaseProstatic Neoplasms

HSP90B1 SF3B1 PPFIBP2 PIK3R1 APC DAG1 MGA

8.27e-04616737C0033578
DiseaseMalignant neoplasm of prostate

HSP90B1 SF3B1 PPFIBP2 PIK3R1 APC DAG1 MGA

8.27e-04616737C0376358
Diseaseinterleukin 18 measurement

BDP1 PIK3R1 BIRC6

8.97e-0476733EFO_0004581
DiseaseGlioblastoma

APC GRIK2 MDM4

1.00e-0379733C0017636
DiseaseGiant Cell Glioblastoma

APC GRIK2 MDM4

1.20e-0384733C0334588
DiseaseStomach Carcinoma

APC FGFR2

1.23e-0321732C0699791
Diseasecholangiocarcinoma (is_implicated_in)

APC PREX2

1.35e-0322732DOID:4947 (is_implicated_in)
DiseaseSchizophrenia

CHL1 CACNA1C RAPGEF6 HPGDS APC GRIK2 FGFR2 PINK1

1.50e-03883738C0036341
Diseasecortical thickness

KIF6 SF3B1 KMT2B MYCBP2 PIK3R1 PPFIBP1 EBNA1BP2 FNBP1L PRKAG2

1.67e-031113739EFO_0004840
Diseasecortical surface area measurement

DCHS2 KIF6 SF3B1 MYCBP2 PIK3R1 PPFIBP1 APC FGFR2 FNBP1L PRKAG2

1.70e-0313457310EFO_0010736
DiseaseBell's palsy

FARP1 GRIK2 MGA

2.09e-03102733EFO_0007167

Protein segments in the cluster

PeptideGeneStartEntry
RHRELVVPQLPARKK

BTN2A3P

571

Q96KV6
HSLPVRKKVLAPRVN

ALKBH2

236

Q6NS38
KRCHKQPLISLPRQR

BRINP3

381

Q76B58
SLIKNKIHRLPVIDP

PRKAG2

376

Q9UGJ0
LNQVPILRTRFQKPK

BDP1

801

A6H8Y1
RPVVRLPSLKHQSNK

BIRC6

1241

Q9NR09
IPQDLLHKVLKSPRL

BTBD16

251

Q32M84
SKLPPVNLIHRDILR

DPPA4

86

Q7L190
KDPKAIPVIHRLQLI

LVRN

676

Q6Q4G3
KQKLCARHVQPRPLV

DAZ2

116

Q13117
KQKLCARHVQPRPLV

DAZ3

116

Q9NR90
QRLLPVVSSLPKLRH

NWD2

916

Q9ULI1
LVHKRSPLRRNQKTP

MTF2

11

Q9Y483
SQPAVHKLTKRIPLR

FGFR2

411

P21802
PLHSVNNPILRKRKL

MAPKAPK5

351

Q8IW41
TIKKQPLHQFVQRPL

NFU1

31

Q9UMS0
KLRVSPKNPRIPKLH

CHL1

516

O00533
LKTKPIHTIIRKRAP

MGA

1031

Q8IWI9
QVRPKLPLLKILHAA

MDM4

26

O15151
QLLNIPPNKTLLRRH

PPFIBP1

851

Q86W92
VLKLNRNRISAIPPK

LRIG3

196

Q6UXM1
HPRLVTLRKKVQAIP

HPGDS

171

O60760
NKKPPLPKRVRRQIH

DAG1

301

Q14118
VLAVLPRLHQLKVPT

EBNA1BP2

116

Q99848
KQLAPHPNIIRVLRA

PINK1

266

Q9BXM7
QKFTQLLLLQRPHPR

NLRP1

276

Q9C000
IQIFARVKPPVRKHQ

KIF6

6

Q6ZMV9
HPLVRAQPELLRKVQ

KLHL40

241

Q2TBA0
KPTLQPVLQLKARRR

KMT2B

1126

Q9UMN6
PLPQCKRHLKQVQLL

MEFV

371

O15553
RLINIRHPISKILSP

MRGPRX3

86

Q96LB0
QLLKKLIRSPSIPHQ

PIK3R1

221

P27986
IPPQKTLLRRHLTTK

PPFIBP2

766

Q8ND30
NIRHLIIPENLKPTK

DCHS2

1406

Q6V1P9
KIPLIHRALQLAQRP

GBA

196

P04062
LIKPHQRITKYPLLL

PLEKHG6

306

Q3KR16
QKKTFEINPRHPLIR

HSP90B1

681

P14625
KPPRAHELKLLVRNI

C2CD2

256

Q9Y426
KQKLCARHVQPRPLV

DAZ1

116

Q9NQZ3
KQKLCARHVQPRPLV

DAZ1

281

Q9NQZ3
KQKLCARHVQPRPLV

DAZ1

446

Q9NQZ3
KHLDVVTLLRRIQPP

CACNA1C

1561

Q13936
VPLRRLKPSQKKHFN

DOC2A

196

Q14183
SHLPPEQRRKKLQQR

FNBP1L

396

Q5T0N5
DLLKPIVKQIRRPKH

FARP1

96

Q9Y4F1
PLVLTEPTRNRLQKK

DMGDH

846

Q9UI17
HKKKLRSPQILVPTL

HEATR1

1216

Q9H583
KQKLCARHVQPRPLV

DAZ4

116

Q86SG3
KQKLCARHVQPRPLV

DAZ4

281

Q86SG3
VLVHIPKQRLGLVKR

C1orf127

101

Q8N9H9
NIRHPEELSLLKKPR

FERMT2

131

Q96AC1
CQRRLKHKPQAPVIV

GRIK2

871

Q13002
SIIKRHPPQRLQKLE

CCDC198

91

Q9NVL8
KHLDVVTLLRRIQPP

CACNA1D

1501

Q01668
DPLARLPQLKRHIKQ

PHF20L1

986

A8MW92
PRLKLLLNHTNILRP

NOXRED1

176

Q6NXP6
LQLQKAKPLTHRRPK

SPATA17

191

Q96L03
RPRVKKLHPQQVLNR

SLFN14

161

P0C7P3
VLQVPAVNLHPIRKK

RAPGEF6

1181

Q8TEU7
KRTIQLPHLKTLILN

TLR10

366

Q9BXR5
RKLRNVSNLKPVPLI

SCCPDH

211

Q8NBX0
LQPKHFRILNPVIIK

ST3GAL5

301

Q9UNP4
KQHSILPARVKAIPR

MYCBP2

3486

O75592
RSLKQHPPLLLDTVK

PEX11A

186

O75192
TSPLVAHRLKPIRQK

PLK4

591

O00444
KLLPSQNRLQPQKHV

APC

1616

P25054
HLPTTKELAKRQRLP

TNRC18

2756

O15417
PLIPKKFQLNQHRRI

SENP5

211

Q96HI0
LQPKRPKTIKQRHVR

RNPC3

266

Q96LT9
PPRFTLKKLVQRLHI

TEP1

436

Q99973
LLPRLTPILKNRHEK

SF3B1

1016

O75533
LRLLLPVPHVKLNVQ

TRPM2

586

O94759
TNQVLLHKIPPRKRL

ZNF274

436

Q96GC6
PKLSCPKRLRLHIKQ

PREX2

1206

Q70Z35
QNRVHPRPLVKLLPK

ZNF200

81

P98182
RQKRSSVLKPLLIQP

YY1AP1

451

Q9H869
KILKALNSRRIIPRP

ZNF644

1091

Q9H582
PKSPQQRLLELLHRS

THRA

436

P10827
KLPIVRHVKLLNLPA

TRAPPC9

536

Q96Q05
KILKRHPGLRNILPI

TUT4

1036

Q5TAX3