Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	antigen binding	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-30-5 IGHV3-30-3 IGHV3-38-3 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64D IGHV3-64	4.15e-27	190	88	23	GO:0003823
GeneOntologyBiologicalProcess	immunoglobulin mediated immune response	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-30-5 EXO1 IGHV3-30-3 SVEP1 IGHV3-38-3 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64D IGHV3-64	3.14e-28	235	89	25	GO:0016064
GeneOntologyBiologicalProcess	B cell mediated immunity	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-30-5 EXO1 IGHV3-30-3 SVEP1 IGHV3-38-3 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64D IGHV3-64	8.24e-28	244	89	25	GO:0019724
GeneOntologyBiologicalProcess	lymphocyte mediated immunity	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-30-5 EXO1 IGHV3-30-3 SVEP1 IGHV3-38-3 NLRP3 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64D IGHV3-64	1.73e-22	449	89	26	GO:0002449
GeneOntologyBiologicalProcess	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-30-5 EXO1 IGHV3-30-3 SVEP1 IGHV3-38-3 NLRP3 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64D IGHV3-64	3.57e-22	462	89	26	GO:0002460
GeneOntologyBiologicalProcess	leukocyte mediated immunity	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 SPHK2 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-30-5 EXO1 IGHV3-30-3 SVEP1 IGHV3-38-3 NLRP3 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64D IGHV3-64	5.78e-21	576	89	27	GO:0002443
GeneOntologyBiologicalProcess	immune effector process	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 SPHK2 IGHV3-33 IGHV3-30 ABL1 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-30-5 EXO1 IGHV3-30-3 SVEP1 IGHV3-38-3 NLRP3 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64D IGHV3-64	1.38e-17	859	89	28	GO:0002252
GeneOntologyBiologicalProcess	adaptive immune response	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-30-5 EXO1 IGHV3-30-3 SVEP1 IGHV3-38-3 NLRP3 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64D IGHV3-64	8.37e-16	838	89	26	GO:0002250
GeneOntologyCellularComponent	immunoglobulin complex	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-30-5 IGHV3-30-3 IGHV3-38-3 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64D IGHV3-64	1.37e-28	166	91	23	GO:0019814
GeneOntologyCellularComponent	Cul2-RING ubiquitin ligase complex	PRAMEF7 ZER1 PRAMEF12 PRAMEF8	5.19e-05	47	91	4	GO:0031462
MousePheno	torticollis	SLC26A4 SLC39A14	1.52e-05	2	55	2	MP:0030126
MousePheno	abnormal spermatogonia proliferation	PRAMEF7 MAST4 PRAMEF12 PRAMEF8	3.37e-05	47	55	4	MP:0002685
Domain	PRAME_family	PRAMEF7 PRAMEF12 PRAMEF8	4.29e-05	19	68	3	IPR026271
Domain	S04_transporter_CS	SLC26A4 SLC26A5	2.71e-04	7	68	2	IPR018045
Domain	DUF1220	NBPF4 NBPF6	4.63e-04	9	68	2	SM01148
Domain	Kinesin-like_fam	KIF26A KIF26B KIF4A	5.13e-04	43	68	3	IPR027640
Domain	KINESIN_MOTOR_1	KIF26A KIF26B KIF4A	5.49e-04	44	68	3	PS00411
Domain	-	KIF26A KIF26B KIF4A	5.49e-04	44	68	3	3.40.850.10
Domain	Kinesin_motor_dom	KIF26A KIF26B KIF4A	5.49e-04	44	68	3	IPR001752
Domain	Kinesin	KIF26A KIF26B KIF4A	5.49e-04	44	68	3	PF00225
Domain	KINESIN_MOTOR_2	KIF26A KIF26B KIF4A	5.49e-04	44	68	3	PS50067
Domain	KISc	KIF26A KIF26B KIF4A	5.49e-04	44	68	3	SM00129
Domain	SLC26A	SLC26A4 SLC26A5	5.77e-04	10	68	2	PS01130
Domain	STAS	SLC26A4 SLC26A5	7.03e-04	11	68	2	PS50801
Domain	STAS_dom	SLC26A4 SLC26A5	7.03e-04	11	68	2	IPR002645
Domain	SLC26A/SulP_dom	SLC26A4 SLC26A5	7.03e-04	11	68	2	IPR011547
Domain	STAS	SLC26A4 SLC26A5	7.03e-04	11	68	2	PF01740
Domain	NBPF_dom	NBPF4 NBPF6	7.03e-04	11	68	2	IPR010630
Domain	SLC26A/SulP_fam	SLC26A4 SLC26A5	7.03e-04	11	68	2	IPR001902
Domain	NBPF	NBPF4 NBPF6	7.03e-04	11	68	2	PS51316
Domain	-	SLC26A4 SLC26A5	7.03e-04	11	68	2	3.30.750.24
Domain	Sulfate_transp	SLC26A4 SLC26A5	7.03e-04	11	68	2	PF00916
Domain	DUF1220	NBPF4 NBPF6	7.03e-04	11	68	2	PF06758
Domain	TIL	VWF ZAN	8.42e-04	12	68	2	PF01826
Domain	C8	VWF ZAN	8.42e-04	12	68	2	PF08742
Domain	Unchr_dom_Cys-rich	VWF ZAN	9.93e-04	13	68	2	IPR014853
Domain	C8	VWF ZAN	9.93e-04	13	68	2	SM00832
Domain	TIL_dom	VWF ZAN	1.16e-03	14	68	2	IPR002919
Domain	VWD	VWF ZAN	1.52e-03	16	68	2	SM00216
Domain	VWF_type-D	VWF ZAN	1.52e-03	16	68	2	IPR001846
Domain	VWFD	VWF ZAN	1.52e-03	16	68	2	PS51233
Domain	VWD	VWF ZAN	1.52e-03	16	68	2	PF00094
Domain	EGF_3	SELL FAT4 ZAN ADAM9 SVEP1	1.65e-03	235	68	5	PS50026
Domain	EGF	SELL FAT4 ZAN ADAM9 SVEP1	1.65e-03	235	68	5	SM00181
Domain	EGF-like_dom	SELL FAT4 ZAN ADAM9 SVEP1	2.13e-03	249	68	5	IPR000742
Domain	VWC_out	VWF ZAN	2.15e-03	19	68	2	SM00215
Domain	Prefoldin	KRT35 DISC1 KIF4A	2.30e-03	72	68	3	IPR009053
Domain	EGF_1	SELL FAT4 ZAN ADAM9 SVEP1	2.36e-03	255	68	5	PS00022
Domain	EGF-like_CS	SELL FAT4 ZAN ADAM9 SVEP1	2.61e-03	261	68	5	IPR013032
Domain	Ankyrin_rpt	ANK3 PPP1R12B EXO1 RIPK4 TCTN2	2.65e-03	262	68	5	IPR002110
Domain	EGF_2	SELL FAT4 ZAN ADAM9 SVEP1	2.79e-03	265	68	5	PS01186
Domain	PID	NUMBL MAPK8IP2	4.64e-03	28	68	2	PF00640
Domain	hEGF	FAT4 SVEP1	4.64e-03	28	68	2	PF12661
Domain	-	ANK3 APAF1 NLRP3	4.74e-03	93	68	3	1.10.533.10
Domain	DEATH-like_dom	ANK3 APAF1 NLRP3	5.64e-03	99	68	3	IPR011029
Domain	PID	NUMBL MAPK8IP2	6.04e-03	32	68	2	PS01179
Domain	-	PRAMEF7 ZER1 PRAMEF12 PRAMEF8 NLRP3	6.26e-03	321	68	5	3.80.10.10
Domain	L_dom-like	PRAMEF7 ZER1 PRAMEF12 PRAMEF8 NLRP3	6.85e-03	328	68	5	IPR032675
Domain	VWFC_1	VWF ZAN	7.60e-03	36	68	2	PS01208
Domain	VWC	VWF ZAN	8.44e-03	38	68	2	SM00214
Domain	VWFC_2	VWF ZAN	8.44e-03	38	68	2	PS50184
Domain	PTB	NUMBL MAPK8IP2	9.32e-03	40	68	2	SM00462
Domain	PTB/PI_dom	NUMBL MAPK8IP2	9.77e-03	41	68	2	IPR006020
Domain	VWF_dom	VWF ZAN	1.02e-02	42	68	2	IPR001007
Pathway	REACTOME_CD22_MEDIATED_BCR_REGULATION	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	8.24e-23	35	62	13	MM17219
Pathway	REACTOME_CLASSICAL_ANTIBODY_MEDIATED_COMPLEMENT_ACTIVATION	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	4.47e-22	39	62	13	MM17212
Pathway	REACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	3.94e-21	45	62	13	MM14912
Pathway	REACTOME_FCGR_ACTIVATION	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	1.03e-20	48	62	13	MM17214
Pathway	REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	4.43e-20	53	62	13	MM15716
Pathway	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	5.81e-20	54	62	13	MM14655
Pathway	REACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	9.85e-20	56	62	13	MM14815
Pathway	REACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	1.63e-19	58	62	13	MM14914
Pathway	REACTOME_FCERI_MEDIATED_MAPK_ACTIVATION	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	2.66e-19	60	62	13	MM14913
Pathway	REACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	2.66e-19	60	62	13	MM14872
Pathway	REACTOME_COMPLEMENT_CASCADE	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	2.98e-17	84	62	13	MM14653
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 ABL1 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	4.73e-17	114	62	14	MM14814
Pathway	REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	5.40e-16	135	62	14	MM14781
Pathway	REACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	8.00e-16	107	62	13	MM14915
Pathway	REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	5.04e-15	158	62	14	MM14812
Pathway	REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	1.19e-14	131	62	13	MM15717
Pathway	REACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	7.03e-14	150	62	13	MM14889
Pathway	REACTOME_HEMOSTASIS	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 VWF IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 KIF26A KIF26B KIF4A IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	2.32e-11	571	62	18	MM14472
Pathway	REACTOME_CD22_MEDIATED_BCR_REGULATION	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	2.15e-10	61	62	8	M27581
Pathway	REACTOME_FCGR_ACTIVATION	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	5.95e-10	69	62	8	M27108
Pathway	REACTOME_SCAVENGING_OF_HEME_FROM_PLASMA	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	5.95e-10	69	62	8	M27150
Pathway	REACTOME_INNATE_IMMUNE_SYSTEM	SELL IGHV3-53 CRISPLD2 IGHV3-48 IGHV3-33 IGHV3-30 ABL1 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 APAF1 ITLN2 CKAP4 FLG2 NLRP3 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	6.13e-10	995	62	21	MM14661
Pathway	REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	7.51e-10	71	62	8	M1078
Pathway	REACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	7.51e-10	71	62	8	M27203
Pathway	REACTOME_PARASITE_INFECTION	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 ABL1 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	1.78e-09	116	62	9	M29843
Pathway	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	1.99e-09	80	62	8	M6121
Pathway	REACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	2.42e-09	82	62	8	M27110
Pathway	REACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	3.56e-09	86	62	8	M27206
Pathway	REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	3.56e-09	86	62	8	M601
Pathway	REACTOME_FCERI_MEDIATED_MAPK_ACTIVATION	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	3.91e-09	87	62	8	M27205
Pathway	REACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	7.91e-09	95	62	8	M29842
Pathway	REACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	1.01e-08	98	62	8	M27152
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 ABL1 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	1.13e-08	143	62	9	M27107
Pathway	REACTOME_VESICLE_MEDIATED_TRANSPORT	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 KIF26A KIF26B KIF4A IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	1.17e-08	645	62	16	MM15232
Pathway	REACTOME_LEISHMANIA_INFECTION	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 ABL1 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7 NLRP3	3.54e-08	219	62	10	M29836
Pathway	REACTOME_COMPLEMENT_CASCADE	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	3.59e-08	115	62	8	M19752
Pathway	REACTOME_ADAPTIVE_IMMUNE_SYSTEM	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 KIF26A KIF4A IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	5.37e-08	719	62	16	MM14540
Pathway	REACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	1.19e-07	134	62	8	M29840
Pathway	REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	1.33e-07	190	62	9	M8240
Pathway	REACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	1.33e-07	136	62	8	M27207
Pathway	REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	1.59e-07	194	62	9	M16312
Pathway	REACTOME_POTENTIAL_THERAPEUTICS_FOR_SARS	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	3.47e-07	154	62	8	M39007
Pathway	REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	6.15e-07	166	62	8	M608
Pathway	REACTOME_HEMOSTASIS	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 ABL1 VWF IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7 KIF26A KIF26B KIF4A	1.07e-06	679	62	14	M8395
Pathway	REACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7	1.45e-06	186	62	8	M27175
Pathway	REACTOME_VESICLE_MEDIATED_TRANSPORT	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 ANK3 IGHV3-13 IGHV3-11 IGHV3-7 KIF26A KIF26B KIF4A	6.29e-05	725	62	12	M27507
Pathway	REACTOME_INNATE_IMMUNE_SYSTEM	SELL IGHV3-53 CRISPLD2 IGHV3-48 IGHV3-33 IGHV3-30 ABL1 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7 APAF1 CKAP4 FLG2 NLRP3	8.29e-05	1128	62	15	M1036
Pathway	REACTOME_SARS_COV_INFECTIONS	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7 NLRP3	2.02e-04	471	62	9	M39009
Pathway	REACTOME_ADAPTIVE_IMMUNE_SYSTEM	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7 KIF26A KIF4A	8.68e-04	828	62	11	M1058
Pathway	WP_DNA_IRDOUBLE_STRAND_BREAKS_AND_CELLULAR_RESPONSE_VIA_ATM	ABL1 APAF1 EXO1	1.81e-03	55	62	3	M39598
Pathway	REACTOME_KINESINS	KIF26A KIF26B KIF4A	2.00e-03	57	62	3	MM15714
Pathway	REACTOME_KINESINS	KIF26A KIF26B KIF4A	2.43e-03	61	62	3	M977
Pubmed	1.3 A X-ray structure of an antibody Fv fragment used for induced membrane-protein crystallization.	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	1.34e-32	15	92	13	12657787
Pubmed	Early onset of somatic mutation in immunoglobulin VH genes during the primary immune response.	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	6.24e-29	22	92	13	2499654
Pubmed	IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes.	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64D IGHV3-64	1.37e-28	77	92	17	15608191
Pubmed	The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus.	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64	3.12e-27	91	92	17	9841928
Pubmed	Structure and physical map of 64 variable segments in the 3'0.8-megabase region of the human immunoglobulin heavy-chain locus.	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-23 IGHV3-16 IGHV3-11 IGHV3-7 IGHV3-64	6.04e-18	39	92	10	8490662
Pubmed	Molecular analysis of spontaneous somatic mutants.	IGHV3-48 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7	1.16e-13	5	92	5	401950
Pubmed	An immunoglobulin promoter region is unaltered by DNA rearrangement and somatic mutation during B-cell development.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	6296789
Pubmed	A biological consequence of variation in the site of D-JH gene rearrangement.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	6434992
Pubmed	Mouse monoclonal antibodies to pneumococcal C-polysaccharide backbone show restricted usage of VH-DH-JH gene segments and share the same kappa chain.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	19428559
Pubmed	Immunoglobulin heavy chain gene organization in mice: analysis of a myeloma genomic clone containing variable and alpha constant regions.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	106394
Pubmed	Somatic evolution of diversity among anti-phosphocholine antibodies induced with Proteus morganii.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	3106498
Pubmed	An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	6769593
Pubmed	Idiotype-specific Th cells support oligoclonal expansion of anti-dsDNA B cells in mice with lupus.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	25127856
Pubmed	Oligodendrocyte-reactive O1, O4, and HNK-1 monoclonal antibodies are encoded by germline immunoglobulin genes.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	8750831
Pubmed	Crossreactive B cells are present during a primary but not secondary response in BALB/c mice expressing a bcl-2 transgene.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	10449099
Pubmed	Specific H chain junctional diversity may be required for non-T15 antibodies to bind phosphorylcholine.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	3135325
Pubmed	Clonal Progression during the T Cell-Dependent B Cell Antibody Response Depends on the Immunoglobulin DH Gene Segment Repertoire.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	25157256
Pubmed	Defective secretion of an immunoglobulin caused by mutations in the heavy chain complementarity determining region 2.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	8046334
Pubmed	Structure of the T15 VH gene subfamily: identification of immunoglobulin gene promotor homologies.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	3108392
Pubmed	The D segment defines the T15 idiotype: the immunoresponse of A/J mice to Pneumococcus pneumoniae.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	6499907
Pubmed	Size differences among immunoglobulin heavy chains from phosphorylcholine-binding proteins.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	819932
Pubmed	Somatic hypermutation of an immunoglobulin transgene in kappa transgenic mice.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	3104790
Pubmed	A V region mutation in a phosphocholine-binding monoclonal antibody results in loss of antigen binding.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	2005389
Pubmed	Repertoire shift in the humoral response to phosphocholine-keyhole limpet hemocyanin: VH somatic mutation in germinal center B cells impairs T15 Ig function.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	12734355
Pubmed	Significant structural and functional change of an antigen-binding site by a distant amino acid substitution: proposal of a structural mechanism.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	2748602
Pubmed	Characterization of gene use and efficacy of mouse monoclonal antibodies to Streptococcus pneumoniae serotype 8.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	21068211
Pubmed	Antibody diversity: somatic hypermutation of rearranged VH genes.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	6101208
Pubmed	Sequence and fine specificity analysis of primary 511 anti-phosphorylcholine antibodies.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	2512348
Pubmed	Developmentally controlled expression of immunoglobulin VH genes.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	4.58e-11	4	92	4	3975629
Pubmed	IgD+IgM- B cells mount immune responses that exhibit altered antibody repertoire.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	2.29e-10	5	92	4	14991595
Pubmed	An intrinsic propensity of murine peritoneal B1b cells to switch to IgA in presence of TGF-β and retinoic acid.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	2.29e-10	5	92	4	24324757
Pubmed	Increased junctional diversity in fetal B cells results in a loss of protective anti-phosphorylcholine antibodies in adult mice.	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	2.29e-10	5	92	4	10367906
Pubmed	Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region.	IGHV3-48 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7	9.67e-10	18	92	5	6788376
Pubmed	Content and organization of the human Ig VH locus: definition of three new VH families and linkage to the Ig CH locus.	IGHV3-15 IGHV3-13 IGHV3-72 IGHV3-66	9.51e-09	10	92	4	3396540
Pubmed	The extracellular loop of pendrin and prestin modulates their voltage-sensing property.	SLC26A4 SLC26A5	6.92e-06	2	92	2	29777056
Pubmed	Functional Studies of Deafness-Associated Pendrin and Prestin Variants.	SLC26A4 SLC26A5	6.92e-06	2	92	2	38474007
Pubmed	Variable region sequences of five human immunoglobulin heavy chains of the VH3 subgroup: definitive identification of four heavy chain hypervariable regions.	IGHV3-23 IGHV3-7	6.92e-06	2	92	2	4522793
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF7 PRAMEF12 PRAMEF8	1.19e-05	17	92	3	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF7 PRAMEF12 PRAMEF8	1.19e-05	17	92	3	37781892
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF7 PRAMEF12 PRAMEF8	1.42e-05	18	92	3	23894331
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF7 PRAMEF12 PRAMEF8	1.42e-05	18	92	3	12890732
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF7 PRAMEF12 PRAMEF8	1.42e-05	18	92	3	29731491
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF7 PRAMEF12 PRAMEF8	1.42e-05	18	92	3	14675769
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF7 PRAMEF12 PRAMEF8	1.42e-05	18	92	3	39181896
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF7 PRAMEF12 PRAMEF8	1.68e-05	19	92	3	28604677
Pubmed	Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.	PRAMEF7 PRAMEF12 PRAMEF8	1.98e-05	20	92	3	26694250
Pubmed	Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.	PRAMEF7 PRAMEF12 PRAMEF8	1.98e-05	20	92	3	16580637
Pubmed	Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.	PRAMEF7 PRAMEF12 PRAMEF8	1.98e-05	20	92	3	21425410
Pubmed	A2E induces IL-1ß production in retinal pigment epithelial cells via the NLRP3 inflammasome.	ABCA4 NLRP3	2.07e-05	3	92	2	23840644
Pubmed	NLRP3 Inflammasome Activation Through Heart-Brain Interaction Initiates Cardiac Inflammation and Hypertrophy During Pressure Overload.	SLC17A9 NLRP3	2.07e-05	3	92	2	36440584
Pubmed	Neutrophil NLRP3 promotes cardiac injury following acute myocardial infarction through IL-1β production, VWF release and NET deposition in the myocardium.	VWF NLRP3	2.07e-05	3	92	2	38914598
Pubmed	Higher-order immunoglobulin repertoire restrictions in CLL: the illustrative case of stereotyped subsets 2 and 169.	IGHV3-48 IGHV3-21	2.07e-05	3	92	2	33036024
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF7 PRAMEF12 PRAMEF8	2.66e-05	22	92	3	31729367
Pubmed	Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.	PRAMEF7 PRAMEF12 PRAMEF8	3.05e-05	23	92	3	19480014
Pubmed	MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.	PRAMEF7 PRAMEF12 PRAMEF8	3.95e-05	25	92	3	37451217
Pubmed	Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.	PRAMEF7 PRAMEF12 PRAMEF8	3.95e-05	25	92	3	12620990
Pubmed	Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.	PRAMEF7 PRAMEF12 PRAMEF8	4.46e-05	26	92	3	18500982
Pubmed	A human MAP kinase interactome.	ZNF106 VWF ANK3 KIF26A KIF26B EXPH5 TNRC6A CDC42BPB	4.58e-05	486	92	8	20936779
Pubmed	Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.	PRAMEF7 PRAMEF12 PRAMEF8	5.59e-05	28	92	3	25089626
Pubmed	Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.	PRAMEF7 PRAMEF12 PRAMEF8	6.91e-05	30	92	3	38786026
Pubmed	LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.	PRAMEF7 PRAMEF12 PRAMEF8	8.40e-05	32	92	3	37889087
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ZNF106 ABL1 MAST4 NUMBL KIF26B EXPH5 EXO1 SIPA1L2 ARHGEF17 MELK	9.49e-05	861	92	10	36931259
Pubmed	Exploring genome-wide - dietary heme iron intake interactions and the risk of type 2 diabetes.	TNRC6A SVEP1	1.03e-04	6	92	2	23386860
Pubmed	L-selectin ligation-induced CSF-1 gene transcription is regulated by AP-1 in a c-Abl kinase-dependent manner.	SELL ABL1	1.03e-04	6	92	2	18619508
Pubmed	Comparison of the human immune response to conjugate and polysaccharide pneumococcal vaccination using a reconstituted SCID mouse model.	IGHV3-49 IGHV3-30	1.03e-04	6	92	2	16860443
Pubmed	Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger.	SLC26A4 SLC26A5	1.03e-04	6	92	2	11087667
Pubmed	Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.	PRAMEF7 PRAMEF12 PRAMEF8	1.10e-04	35	92	3	19389355
Pubmed	All kinesin superfamily protein, KIF, genes in mouse and human.	KIF26A KIF26B KIF4A	1.30e-04	37	92	3	11416179
Pubmed	Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation.	IGHV3-38-3 IGHV3-64D	1.44e-04	7	92	2	23541343
Pubmed	Myosin-reactive autoantibodies in rheumatic carditis and normal fetus.	IGHV3-48 IGHV3-30	1.44e-04	7	92	2	9614934
Pubmed	Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition.	APAF1 NLRP3	1.44e-04	7	92	2	33308446
Pubmed	Splice variant IVS2-2A>G in the SLC26A5 (Prestin) gene in five Estonian families with hearing loss.	SLC26A4 SLC26A5	1.92e-04	8	92	2	19027966
Pubmed	Genetic analysis of presbycusis by arrayed primer extension.	SLC26A4 SLC26A5	1.92e-04	8	92	2	18988928
Pubmed	Genotyping with a 198 mutation arrayed primer extension array for hereditary hearing loss: assessment of its diagnostic value for medical practice.	SLC26A4 SLC26A5	1.92e-04	8	92	2	20668687
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	FAT4 ANK3 SLFN13 TNRC6A KIF4A INSM2 SLC39A14 FLG2 CDC42BPB	2.20e-04	777	92	9	35844135
Pubmed	Physiological roles and regulation of mammalian sulfate transporters.	SLC26A4 SLC26A5	2.46e-04	9	92	2	11581495
Pubmed	Abl kinases are required for vascular function, Tie2 expression, and angiopoietin-1-mediated survival.	ABL1 VWF	2.46e-04	9	92	2	23840065
Pubmed	Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells.	PRAMEF7 PRAMEF12 PRAMEF8	2.50e-04	46	92	3	17287250
Pubmed	NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation.	ABL1 ABI3	3.07e-04	10	92	2	17101133
Pubmed	N-glycosylation and topology of the human SLC26 family of anion transport membrane proteins.	SLC26A4 SLC26A5	3.07e-04	10	92	2	24647542
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	PRAMEF7 PRAMEF12 PRAMEF8	3.21e-04	50	92	3	31806660
Pubmed	The global gene-expression profiles of U-937 human macrophages treated with Tat peptide and Tat-FITC conjugate.	ABL1 APAF1 GPR135	3.60e-04	52	92	3	22632162
Pubmed	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	FAT4 ANK3	3.75e-04	11	92	2	20351715
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	IGHV3-49 VWF ANK3 IGHV3-15 NUMBL PPP1R12B SIPA1L2 ARHGEF17 CDC42BPB MAPK8IP2 IGHV3-73 IGHV3-72	3.90e-04	1431	92	12	37142655
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	PRAMEF7 ZNF106 ABL1 RHBDF1 PRAMEF12 PRAMEF8	4.16e-04	363	92	6	14691545
Pubmed	The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops.	IGHV3-21 IGHV3-74	4.49e-04	12	92	2	1404388
Pubmed	ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation.	PRAMEF7 PRAMEF12 PRAMEF8	4.97e-04	58	92	3	31598710
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	RHBDF1 ANK3 NUMBL KIF26B ADAM9 CDC42BPB	5.08e-04	377	92	6	38117590
Pubmed	An abundance of X-linked genes expressed in spermatogonia.	PRAMEF7 PRAMEF12 PRAMEF8	5.23e-04	59	92	3	11279525
Pubmed	Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling.	TBX18 VWF	5.30e-04	13	92	2	23178125
Pubmed	The ATP Transporter VNUT Mediates Induction of Dectin-1-Triggered Candida Nociception.	SLC17A9 NLRP3	5.30e-04	13	92	2	30240621
Pubmed	Slit-roundabout signaling regulates the development of the cardiac systemic venous return and pericardium.	TBX18 ROBO4	7.11e-04	15	92	2	23255421
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	CRISPLD2 PRAMEF7 KRT35 PRAMEF12 PRAMEF8 FLG2 TCTN2	7.59e-04	564	92	7	21565611
Pubmed	Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis.	SELL DISC1	8.11e-04	16	92	2	19451621
Pubmed	Fat4-Dchs1 signalling controls cell proliferation in developing vertebrae.	TBX18 FAT4	8.11e-04	16	92	2	27381226
Pubmed	Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease.	FAT4 DISC1	9.17e-04	17	92	2	22153077
Pubmed	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	ANK3 SVEP1	1.15e-03	19	92	2	18711365
Pubmed	Bcl11b/Ctip2 is required for development of lingual papillae in mice.	KRT35 KRT84	1.41e-03	21	92	2	27287879
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF4 NBPF6	1.41e-03	21	92	2	16079250
Pubmed	Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo.	APAF1 EVX1	1.41e-03	21	92	2	10421635
Cytoband	14q32.33	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 KIF26A IGHV3-30-5 IGHV3-30-3 IGHV3-38-3 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64	6.81e-33	228	92	23	14q32.33
Cytoband	Ensembl 112 genes in cytogenetic band chr14q32	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 KIF26A CDC42BPB IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64D IGHV3-64	2.77e-22	566	92	22	chr14q32
Cytoband	1p36.21	PRAMEF7 PRAMEF12 PRAMEF8	2.83e-04	63	92	3	1p36.21
GeneFamily	Immunoglobulin heavy locus at 14q32.33	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-30-5 IGHV3-30-3 IGHV3-38-3 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64	1.91e-26	187	75	22	349
GeneFamily	PRAME family	PRAMEF7 PRAMEF12 PRAMEF8	1.30e-04	24	75	3	686
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF26A KIF26B KIF4A	9.16e-04	46	75	3	622
GeneFamily	Neuroblastoma breakpoint family	NBPF4 NBPF6	4.06e-03	23	75	2	662
GeneFamily	Ataxins\|Trinucleotide repeat containing	NUMBL TNRC6A	4.79e-03	25	75	2	775
Coexpression	XU_CREBBP_TARGETS_DN	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	2.83e-21	56	85	13	MM642
Coexpression	YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	1.25e-17	102	85	13	MM872
Coexpression	RASHI_RESPONSE_TO_IONIZING_RADIATION_6	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D IGHV3-64	3.98e-16	132	85	13	MM996
Coexpression	SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12	IGHV3-33 IGHV3-23 IGHV3-21 IGHV3-7 TAPBPL SLC26A4 ZER1 IGHV3-73 IGHV3-72	9.33e-07	318	85	9	M2429
Coexpression	VANASSE_BCL2_TARGETS_UP	IGHV3-49 IGHV3-15 IGHV3-73 IGHV3-72	1.15e-05	43	85	4	MM799
Coexpression	SALVADOR_MARTIN_PEDIATRIC_TBD_ANTI_TNF_THERAPY_NONRESPONDER_POST_TREATMENT_DN	IGHV3-48 IGHV3-7 IGHV3-74	1.79e-05	16	85	3	M41742
Coexpression	MATTIOLI_MGUS_VS_PCL	IGHV3-33 IGHV3-23 IGHV3-21 IGHV3-7 IGHV3-72	5.94e-05	127	85	5	M10973
CoexpressionAtlas	AravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500_k-means-cluster#2	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66	3.79e-10	163	77	10	Arv_SC-hpx_blastocyst_500_K2
CoexpressionAtlas	AravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_500_k-means-cluster#3	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66	7.61e-10	175	77	10	Arv_SC-H9hpx_500_K3
CoexpressionAtlas	AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000_k-means-cluster#5	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-7 IGHV3-74 IGHV3-72 IGHV3-66	1.18e-09	183	77	10	Arv_SC_fibroblast_1000_K5
CoexpressionAtlas	AravindRamakr_StemCell-HD_top-relative-expression-ranked_1000_k-means-cluster#3	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-7 IGHV3-74 IGHV3-72 IGHV3-66	1.18e-09	183	77	10	Arv_SC-HD_1000_K3
CoexpressionAtlas	AravindRamakr_StemCell-HD_top-relative-expression-ranked_500_k-means-cluster#2	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-7 IGHV3-72	1.83e-08	126	77	8	Arv_SC-HD_500_K2
CoexpressionAtlas	AravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_1000_k-means-cluster#4	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66	1.87e-08	244	77	10	Arv_SC-H9hpx_1000_K4
CoexpressionAtlas	AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500_k-means-cluster#3	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-7 IGHV3-72	3.96e-08	139	77	8	Arv_SC_fibroblast_500_K3
CoexpressionAtlas	AravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000_k-means-cluster#2	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66	4.22e-08	266	77	10	Arv_SC-hpx_blastocyst_1000_K2
CoexpressionAtlas	AravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_500	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66	1.11e-05	492	77	10	Arv_SC-H9hpx_500
CoexpressionAtlas	AravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66	1.11e-05	492	77	10	Arv_SC-hpx_blastocyst_500
CoexpressionAtlas	AravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_2500_k-means-cluster#4	IGHV3-48 IGHV3-33 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66	2.34e-05	426	77	9	Arv_SC-hpx_blastocyst_2500_K4
CoexpressionAtlas	AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_2500_k-means-cluster#5	IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 ITLN2 IGHV3-74 IGHV3-72 IGHV3-66	3.27e-05	341	77	8	Arv_SC_fibroblast_2500_K5
CoexpressionAtlas	AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-7 TMEM151B RIPK4 ITLN2 IGHV3-74 IGHV3-72 IGHV3-66	5.00e-05	986	77	13	Arv_SC_fibroblast_1000
CoexpressionAtlas	AravindRamakr_StemCell-HD_top-relative-expression-ranked_1000	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-7 TMEM151B RIPK4 ITLN2 IGHV3-74 IGHV3-72 IGHV3-66	5.00e-05	986	77	13	Arv_SC-HD_1000
CoexpressionAtlas	AravindRamakr_StemCell-HD_top-relative-expression-ranked_2500_k-means-cluster#4	IGHV3-33 IGHV3-30 IGHV3-11 ITLN2 IGHV3-74 IGHV3-72 IGHV3-66	1.46e-04	315	77	7	Arv_SC-HD_2500_K4
CoexpressionAtlas	geo_heart_top-relative-expression-ranked_2500_k-means-cluster#2	CRISPLD2 IGHV3-48 ZNF106 IGHV3-33 IGHV3-30 IGHV3-21 IGHV3-11 IGHV3-7 PKD1L1 SIPA1L2 SVEP1 IGHV3-74 IGHV3-72	2.02e-04	1133	77	13	geo_heart_2500_K2
CoexpressionAtlas	AravindRamakr_StemCell-HD_top-relative-expression-ranked_500	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-7 IGHV3-72	3.91e-04	489	77	8	Arv_SC-HD_500
CoexpressionAtlas	AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-7 IGHV3-72	3.91e-04	489	77	8	Arv_SC_fibroblast_500
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64D IGHV3-64	1.87e-25	190	89	18	79ee6d10dfbb775da149a1104da5823cf63bbb46
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64D IGHV3-64	1.87e-25	190	89	18	18762ce78ed0b206ade19e1c8ff76a2647489f68
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64	2.75e-25	194	89	18	6ef4aeb8d8e35e4df58ff2a8256caa2113291de9
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 IGHV3-7 SLC17A9 EVX1 IGHV3-74 IGHV3-72 IGHV3-66 IGHV3-64	1.59e-23	193	89	17	34f6c13884fdf7f8a87f942fcb36a58cfac3f65d
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64	1.90e-23	195	89	17	f3f7f1a77a1edd2b50a8211c76fe289738eb04cf
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-72 IGHV3-64	1.61e-20	179	89	15	837ed81f18257f444eaeadc4fac89deedd4e3061
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-72 IGHV3-64	1.61e-20	179	89	15	b6ee4f41d8fb5f047b7bdd8489dda0a89fc6d43f
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-72 IGHV3-66 IGHV3-64	5.10e-20	193	89	15	282b47dae6043eabb1e13d41d91c07b5ec21cd65
ToppCell	COVID_vent-Lymphocytic-Plasma_cell-IgM_Plasmablast\|COVID_vent / Disease condition, Lineage, Cell class and subclass	IGHV3-53 IGHV3-48 IGHV3-38 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-72 IGHV3-66 IGHV3-64	6.45e-20	196	89	15	026a06d8d2089806823e6f6453d3ede84ae93bc6
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELL IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-72 IGHV3-66	6.97e-20	197	89	15	2662138671262b30508c5759038bcdcfe6551696
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-64	7.44e-19	177	89	14	4c434a7b7cc54cf4dac996bbc3f5124d9ef9a9cd
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-64	7.44e-19	177	89	14	d746122bf8d208c3aa4d156e8c12d0a0e555c6e5
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-64	7.44e-19	177	89	14	fc40918825b7e1eb6861df59dfca944778a64b98
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 FAM177B IGHV3-74 IGHV3-66	8.07e-19	178	89	14	107dae8b00c4257697a63700e72bb434cdb8406f
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-7 IGHV3-66 IGHV3-64D IGHV3-64	1.02e-18	181	89	14	e47664a264a2c37390d1668ce04eef2e0172f4cb
ToppCell	healthy_donor-Lymphocytic-Plasma_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	IGHV3-53 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-11 IGHV3-7 CKAP4 IGHV3-74 IGHV3-66 IGHV3-64	1.76e-18	188	89	14	bd53b0371154cff680226897b61c9809a239d1b6
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell-IgM_Plasmablast\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IGHV3-53 IGHV3-48 IGHV3-38 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-13 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-64	2.55e-18	193	89	14	7b4b0271e4fbece703876acb053ae236afb7cdba
ToppCell	Biopsy_IPF-Immune-Plasma_cells\|Biopsy_IPF / Sample group, Lineage and Cell type	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-72 IGHV3-66	3.17e-18	196	89	14	a1b6a8000b86efcb07843998aa3a49bb1f54bcda
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-74 IGHV3-72 IGHV3-66 IGHV3-64	3.41e-18	197	89	14	1e63879633f20646e44873ae6b662f6faf4806fd
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 FAM177B IGHV3-66 IGHV3-64	3.41e-18	197	89	14	9fe1b757f76c2d43d39aa9ac500eaba98723985c
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-53 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-11 IGHV3-7 IGHV3-72 IGHV3-64	4.35e-17	179	89	13	494febe77c6d4e6a2c6f0928bbf4c84b0301f188
ToppCell	cellseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-74 IGHV3-66	5.81e-17	183	89	13	5ab4aa0304b832f98fff89b6c24ad5b7dd014c11
ToppCell	Mild_COVID-19-B_cell\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 FAM177B IGHV3-73 IGHV3-66 IGHV3-64	5.81e-17	183	89	13	dea119e2988e954475f557f0bbe12556a83e81a4
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-74 IGHV3-64D IGHV3-64	6.71e-17	185	89	13	0fff2608f507e019ebb69c27e58fd5be3b049bef
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-74 IGHV3-64D IGHV3-64	6.71e-17	185	89	13	79edc1eeb7b5b9123961ac3ecf398ee68d9dddb9
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66	6.71e-17	185	89	13	08bc817908076734d66f2805cb954141f2cc5a18
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66	6.71e-17	185	89	13	1704a12153a9b107bf03ecccd1a036cf61334d7a
ToppCell	Mild_COVID-19-B_cell-B_cell\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 FAM177B IGHV3-73 IGHV3-66 IGHV3-64	7.20e-17	186	89	13	855a5a00ba2aa1b5c63b8db56d026ddecc546050
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-72 IGHV3-66 IGHV3-64	1.34e-16	195	89	13	13f4ee21568fd747608412d33559d10561dbb3c8
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-72 IGHV3-66 IGHV3-64	1.43e-16	196	89	13	c38e7f533c619afe008de0e99042f7180c2da918
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IGHV3-38 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-13 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-74 IGHV3-66	1.43e-16	196	89	13	fec21383435779bf4c632decd3d29c6ca7baebfb
ToppCell	367C-Lymphocytic-Plasma_cell-\|367C / Donor, Lineage, Cell class and subclass (all cells)	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 IGHV3-7 IGHV3-72 IGHV3-66	8.49e-16	167	89	12	f2185eb72f0137136f6d71af2a70168fded6c940
ToppCell	367C-Lymphocytic-Plasma_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 IGHV3-7 IGHV3-72 IGHV3-66	8.49e-16	167	89	12	5e768cf24699893e05d1bcb1c92dba2336943a64
ToppCell	3'_v3-bone_marrow-Lymphocytic_B_plasma-Plasma_cells\|bone_marrow / Manually curated celltypes from each tissue	IGHV3-53 IGHV3-48 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 SLC17A9 IGHV3-74 IGHV3-66	1.50e-15	175	89	12	51301f3f44d3e88397f367cedd1e2abaa2be4c6f
ToppCell	Control-Lymphoid_P-Plasmablast\|Control / Disease group, lineage and cell class	IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-74	1.60e-15	176	89	12	4b4416f342b732d2cc60133838728880326257d8
ToppCell	Control-Lymphoid_P\|Control / Disease group, lineage and cell class	IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-74	1.60e-15	176	89	12	d895a6b295cd649273ff80ad7785a3e0ae4c728a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IGHV3-48 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-74 IGHV3-72 IGHV3-64	1.72e-15	177	89	12	c2b0fb5921eea24d248d6e6ccb57c29b0832602c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IGHV3-48 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-74 IGHV3-72 IGHV3-64	1.72e-15	177	89	12	111fb0707ff37ca631d85bb5a09e067ffe568eb8
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-53 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 SLC17A9 IGHV3-73 IGHV3-72 IGHV3-66 IGHV3-64	2.11e-15	180	89	12	e3877f6ef5f54ff689058b4c996ab1851822f871
ToppCell	BAL-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 FAM177B IGHV3-66 IGHV3-64D	2.93e-15	185	89	12	609080adb2cfb105bb7b8efb617553833299f371
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64	5.20e-15	194	89	12	a4a70369541876e1192df8828b63e3d1746ae3d9
ToppCell	Biopsy_Other_PF-Immune-Plasma_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	IGHV3-53 IGHV3-48 IGHV3-35 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-7 IGHV3-72 IGHV3-66 IGHV3-64	5.54e-15	195	89	12	d0305c6a68c9e361507b04db94f86873085d49b3
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-7 PKD1L1 IGHV3-72	5.54e-15	195	89	12	df009b18898c10686f75cf72b4ec0eff18f5bb50
ToppCell	Biopsy_Control_(H.)-Immune-Plasma_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	IGHV3-53 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-7 SLC17A9 CKAP4 IGHV3-66	6.26e-15	197	89	12	275f38ed7e477000e864cecf9b7d49ae134c3b6a
ToppCell	Control-Control-Lymphocyte-B-Plasmablast\|Control / Disease, condition lineage and cell class	IGHV3-49 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 SLC17A9 CKAP4 IGHV3-74 IGHV3-64	7.07e-15	199	89	12	c11aa8bca3723a886e7082ae48bb922dd8396be4
ToppCell	healthy_donor-Lymphocytic-Plasma_cell-IgG_Plasmablast\|healthy_donor / Disease condition, Lineage, Cell class and subclass	IGHV3-53 IGHV3-35 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-11 IGHV3-7 CKAP4 IGHV3-74 IGHV3-73 IGHV3-72	1.32e-14	152	89	11	a2ba2d95ac9010e1a62db34dcad10d004f8a90cc
ToppCell	healthy_donor-Lymphocytic-Plasma_cell-IgM_Plasmablast\|healthy_donor / Disease condition, Lineage, Cell class and subclass	IGHV3-53 IGHV3-48 IGHV3-38 IGHV3-33 IGHV3-23 IGHV3-16 IGHV3-11 NBPF6 IGHV3-74 IGHV3-66 IGHV3-64	3.51e-14	166	89	11	2b7b580bec8d9467b0deaf97098065f72dbf2a4f
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-7 INSM2 IGHV3-73 IGHV3-64D	5.55e-14	173	89	11	0ca2169a275404118038c0489a48062879488765
ToppCell	COPD-Lymphoid-B_Plasma\|World / Disease state, Lineage and Cell class	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-16 IGHV3-15 IGHV3-7 IGHV3-64D IGHV3-64	6.30e-14	175	89	11	d73ee324479172501481b54967a0f3bd870fcf3a
ToppCell	BAL-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-53 IGHV3-49 IGHV3-30 IGHV3-23 IGHV3-13 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-72 IGHV3-66 IGHV3-64	8.60e-14	180	89	11	6a777a308fa3160d31eda468db930e71862020b2
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 FAM177B IGHV3-66	1.10e-13	184	89	11	3f8a359e40bebe58545f708682e5e5d1b70cf5cb
ToppCell	10x5'-Liver-Lymphocytic_B_plasma-Plasma_cells\|Liver / Manually curated celltypes from each tissue	IGHV3-48 IGHV3-30 IGHV3-23 IGHV3-15 IGHV3-7 CKAP4 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-64D IGHV3-64	1.10e-13	184	89	11	6f70d8f8ab8362d51f8a58735d42223e06566397
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 FAM177B IGHV3-66	1.10e-13	184	89	11	64bede8db709fd32f40c03265b96f0b12155bb8a
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-53 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-72 IGHV3-66	1.39e-13	188	89	11	6844cebca177fdf38b21a40d606230a033717a3a
ToppCell	5'-Adult-LargeIntestine-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-72 IGHV3-64	1.65e-13	191	89	11	d1d30279ed4612b4f62c225d9eabf0b8a7a09d11
ToppCell	COVID-19-Lymphoid-Plasma,_B_cells\|COVID-19 / Condition, Lineage and Cell class	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-15 IGHV3-11 IGHV3-7 KIF4A IGHV3-74 IGHV3-66 IGHV3-64	1.85e-13	193	89	11	bffd97a73365e1dd23ff3b0320b4860f04ec091a
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-53 IGHV3-48 IGHV3-38 IGHV3-35 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 SLC17A9 IGHV3-74 IGHV3-66	2.08e-13	195	89	11	2d18f08f33f3b261c77b8adf87d1a184cc6d7400
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 IGHV3-7 FAM177B	2.20e-13	196	89	11	e9fe5090452ffdde4bb81b62d57037d823281d00
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 IGHV3-7 FAM177B	2.32e-13	197	89	11	88b29d205237f07a9a26cc15a1cf4ed4816a4c4b
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-11 FAM177B	2.32e-13	197	89	11	76465bb2408c7c75f694e8f7cf1a606b796afc3a
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_cell-B_naive\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELL IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-7 FAM177B IGHV3-74 IGHV3-73	2.45e-13	198	89	11	79c690d21d3420d0bb1a3b3b4ea2c9aa3810a219
ToppCell	tumor_Lung-B_lymphocytes-Plasma_cells\|tumor_Lung / Location, Cell class and cell subclass	IGHV3-53 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-73 IGHV3-72	1.68e-12	169	89	10	b36b7632ce55fc7b6b8b66020563d360b3de6fd7
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELL IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-64D IGHV3-64	1.79e-12	170	89	10	ee2ee67d90ae4596de8ccd620e37c82cf51651d4
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELL IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-64D IGHV3-64	1.79e-12	170	89	10	d7ca0c6ce5d2b7de99346f87e07aa7fe728fa08a
ToppCell	BAL-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELL IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-64D IGHV3-64	1.79e-12	170	89	10	52787f6d529c285d9f0c04cc022710ead5b89b3f
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-53 IGHV3-49 IGHV3-38 IGHV3-23 IGHV3-11 EXO1 KIF4A MELK IGHV3-74 IGHV3-64	1.89e-12	171	89	10	13126a3fbee181412c13ffb0c347277b9d8f16f7
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-16 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74	2.13e-12	173	89	10	7e6bfe85f60834f317941b70d6e0dc3bd527d293
ToppCell	(2)_Plasma_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-7 SLC17A9 IGHV3-72 IGHV3-66	2.67e-12	177	89	10	ed3c936bb69f9bc7291b4f6cde1d204078117c48
ToppCell	VE-plasma\|VE / Condition, Cell_class and T cell subcluster	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 SLC17A9 CKAP4	2.67e-12	177	89	10	0c1cc0834de55717cb4f69d020339060ce2c9a03
ToppCell	VE-plasma-\|VE / Condition, Cell_class and T cell subcluster	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 SLC17A9 CKAP4	2.67e-12	177	89	10	3a3c94cf30012e2aa266bc4d7fe772e45fa90f6d
ToppCell	Mild-Lymphoid-B\|Mild / Condition, Lineage, Cell class and cell subclass	SELL IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-7 FAM177B IGHV3-72 IGHV3-66 IGHV3-64D	3.73e-12	183	89	10	9b64d2d143525e6f48a191facfd101462ff36324
ToppCell	Mild-Lymphoid-B-\|Mild / Condition, Lineage, Cell class and cell subclass	SELL IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-7 FAM177B IGHV3-72 IGHV3-66 IGHV3-64D	3.73e-12	183	89	10	b5740f05a4dcdbbf24f7bf7a3f57ac01a5e75f60
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-15 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-72 IGHV3-64D	3.73e-12	183	89	10	cf5c98f451a568308c52da5c926543dd4836c6b2
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-66	3.93e-12	184	89	10	15f2c10101ccc8ed059520fc082ee42593dff269
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-53 IGHV3-49 IGHV3-48 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-66	3.93e-12	184	89	10	a90a58d9e319afa1cd572e4c2f516fadc42f56e5
ToppCell	10x5'-Liver-Lymphocytic_B_plasma\|Liver / Manually curated celltypes from each tissue	IGHV3-53 IGHV3-48 IGHV3-23 IGHV3-7 CKAP4 IGHV3-74 IGHV3-73 IGHV3-72 IGHV3-64D IGHV3-64	4.38e-12	186	89	10	a2c7430781f432c9c90ac4d620f4518ff767a223
ToppCell	3'_v3-bone_marrow-Lymphocytic_B_plasma\|bone_marrow / Manually curated celltypes from each tissue	IGHV3-53 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-7 SLC17A9 IGHV3-74 IGHV3-72	5.14e-12	189	89	10	dceb011216deb4ffd830144a53c635c05dff5ec5
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_cell-B_mature\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELL IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-15 IGHV3-11 IGHV3-7 FAM177B	7.37e-12	196	89	10	c2e17f3b2217f20bd7f28a1db4aa7d9a95c52a9c
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IGHV3-38 IGHV3-30 IGHV3-23 IGHV3-15 IGHV3-13 IGHV3-11 SLC17A9 IGHV3-74 IGHV3-66	7.37e-12	196	89	10	b3d5540fe8ab9a9cbb9ab5350f5cb0e1aae93584
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELL IGHV3-48 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-7 FAM177B IGHV3-74 IGHV3-66	7.75e-12	197	89	10	0e56255862fed099e771ebd2529393dc5a3641ba
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_cell-B_mature\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELL IGHV3-48 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-7 IGHV3-74 IGHV3-72 IGHV3-66	7.75e-12	197	89	10	da175e66d0a743a1b91d46f224b5ff1d37aa5410
ToppCell	10x5'-blood-Lymphocytic_B_plasma\|blood / Manually curated celltypes from each tissue	IGHV3-48 IGHV3-38 IGHV3-33 IGHV3-16 IGHV3-13 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-64	2.02e-11	150	89	9	6bab0a8bf78ed7de9e1b67ede7496488f80f4863
ToppCell	368C-Lymphocytic-Plasma_cell-\|368C / Donor, Lineage, Cell class and subclass (all cells)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-21 IGHV3-11 SLC17A9 IGHV3-74 IGHV3-72 IGHV3-66	4.04e-11	162	89	9	c21a54310b239d999bbc9d8fb5e8fda16e0bc336
ToppCell	368C-Lymphocytic-Plasma_cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-21 IGHV3-11 SLC17A9 IGHV3-74 IGHV3-72 IGHV3-66	4.04e-11	162	89	9	f945688815229c8386cbcbf46deee7df316fa8d3
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGHV3-53 IGHV3-38 IGHV3-33 IGHV3-15 IGHV3-11 IGHV3-7 IGHV3-74 IGHV3-66 IGHV3-64D	5.30e-11	167	89	9	afb6d0993f3fd44a295874673055189d514f7b11
ToppCell	BAL-Mild-Lymphocyte-B\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-64D IGHV3-64	5.90e-11	169	89	9	307571e57c3bfdf15f0fe1a8b36585e8e4f8a207
ToppCell	10x5'-Liver-Lymphocytic_B_plasma-Plasmablasts\|Liver / Manually curated celltypes from each tissue	IGHV3-53 IGHV3-48 IGHV3-23 IGHV3-7 EXO1 KIF4A MELK IGHV3-66 IGHV3-64D	8.92e-11	177	89	9	1d88ae316d65ca5fdc736c9da93885b6b40c32bb
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELL IGHV3-49 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7 FAM177B	9.38e-11	178	89	9	6f50e2ee66bd9dc12fd3c9ea70e6d50ff76b02e8
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELL IGHV3-49 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7 FAM177B	9.38e-11	178	89	9	b132605f237e766a21042b9a65a564d64c4fec10
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELL IGHV3-49 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7 FAM177B	9.38e-11	178	89	9	99cd5e517855f1a2d6d75fb2d439751f884862c1
ToppCell	367C-Lymphocytic-Plasma_cell-\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-15 IGHV3-11 IGHV3-7 SLC17A9 CKAP4	1.26e-10	184	89	9	14a5288d861260f63fbe0cbea3569cf643e7597e
ToppCell	367C-Lymphocytic-Plasma_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-15 IGHV3-11 IGHV3-7 SLC17A9 CKAP4	1.26e-10	184	89	9	fc708a5c8a7b19fab973c72dc4383a7d30f8b59a
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells\|lymph-node_spleen / Manually curated celltypes from each tissue	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-7 SLC17A9 CKAP4	1.53e-10	188	89	9	c7b1807c96f87fbcd37739a159cf00f9a1ff5d71
ToppCell	COVID-19-Lymphoid-Plasma,_B_cells\|Lymphoid / Condition, Lineage and Cell class	IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-15 IGHV3-11 IGHV3-7 SLC17A9 CKAP4 IGHV3-64	1.76e-10	191	89	9	bcdadf83cb9653f9cc2a281e7c1095fe8f79173c
ToppCell	Biopsy_Other_PF-Immune-B_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	SELL IGHV3-33 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-11 IGHV3-7 FAM177B	2.21e-10	196	89	9	123cd893fd1ae315a655e909c08528f82e9013ff
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell-IgG_Plasmablast\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IGHV3-53 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7 SLC17A9 IGHV3-66	2.31e-10	197	89	9	b754fad4f3caae6de95df901fd96ea8697fe41b1
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell-IgA_Plasmablast\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-72	2.31e-10	197	89	9	fdbf4eb9fa5aefb4ffb307494fe4774bf5e0aaeb
ToppCell	COVID_vent-Lymphocytic-Plasma_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	IGHV3-53 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 SLC17A9 IGHV3-64	2.42e-10	198	89	9	e84c5f712e1dea548d0e2aba6625598f9671d3a0
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_cell-B_mature\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELL IGHV3-53 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-13 IGHV3-7 FAM177B	2.42e-10	198	89	9	d51ee880acc5804cd918105fac846a1528333d6c
ToppCell	metastatic_Lymph_Node-B_lymphocytes-Plasma_cells\|metastatic_Lymph_Node / Location, Cell class and cell subclass	IGHV3-49 IGHV3-48 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-15 IGHV3-11 IGHV3-73	4.59e-10	142	89	8	5ba3a33c2ee20be8baaed97536ca6e9d1de6752f
Disease	tumor necrosis factor ligand superfamily member 11 measurement	IGHV3-21 IGHV3-11 IGHV3-7	5.18e-06	13	79	3	EFO_0010617
Disease	fibroblast growth factor 8 isoform A measurement	IGHV3-7 IGHV3-64D	7.08e-06	2	79	2	EFO_0020385
Disease	dynein light chain 1, cytoplasmic measurement	IGHV3-7 IGHV3-64D	2.12e-05	3	79	2	EFO_0020339
Disease	dietary heme iron intake measurement, type 2 diabetes mellitus	TNRC6A SVEP1	1.05e-04	6	79	2	EFO_0008355, MONDO_0005148
Disease	schizophrenia (is_marker_for)	VWF ANK3 DISC1	2.26e-04	44	79	3	DOID:5419 (is_marker_for)
Disease	allergic sensitization measurement	IGHV3-73 IGHV3-72 IGHV3-64	6.23e-04	62	79	3	EFO_0005298
Disease	Anhedonia	ANK3 DISC1	1.88e-03	24	79	2	C0178417
Disease	Alzheimer disease	ABI3 ANK3 DISC1 TNRC6A SIPA1L2 IGHV3-64	1.93e-03	485	79	6	MONDO_0004975
Disease	glycerol measurement	FAT4 SIPA1L2	2.21e-03	26	79	2	EFO_0010115
Disease	brain cancer (implicated_via_orthology)	NUMBL INSM2	2.21e-03	26	79	2	DOID:1319 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
CSENTLSRARSFSTG	AGBL5	631	Q8NDL9
RCSAFSVDSTLLATG	APAF1	1131	O14727
AAAASSSASCSRRLG	CKAP4	91	Q07065
LSTFFSKASLAAACS	ABCA4	751	P78363
TCASTSRSDSFLTFA	EVX1	371	P49640
SFHCSLTSGVTSLFS	FAT4	3646	Q6V0I7
FTSSFSFIRLSLGSA	DISC1	206	Q9NRI5
CGVTAAFDASRTSFA	NUMBL	206	Q9Y6R0
RGLSSTTCSFSANAD	NBPF4	531	Q96M43
STDFRACFTTSRATS	RBM44	471	Q6ZP01
RLRLSSFSCGQASAT	MELK	331	Q14680
RLSAASSAFSLASAG	ABI3	201	Q9P2A4
GARASCSSSSIAASY	ARHGEF17	226	Q96PE2
CGRFSNSSSSNEFSK	FLG2	401	Q5D862
SLRLSCAASGFTVSS	IGHV3-66	36	A0A0C4DH42
SLRLSCAASGFTFSD	IGHV3-72	36	A0A0B4J1Y9
FSSCSGGRSSSVRFV	KRT84	576	Q9NSB2
SLRLSCAASGFTFSD	IGHV3-11	36	P01762
GSLRLSCAASGFTFS	IGHV3-64	36	A0A075B6Q5
SLRLSCAASGFTFSS	IGHV3-30-5	36	P0DP03
SLRLSCAASGFTFSN	IGHV3-15	36	A0A0B4J1V0
SLRLSCAASGFTFSS	IGHV3-7	36	P01780
SLRLSCAASGFTFSS	IGHV3-30-3	36	P0DP02
SLRLSCAASGFTVSS	IGHV3-38	36	A0A0C4DH36
SLRLSCAASGFTVSS	IGHV3-38-3	36	P0DTE1
TSTGTSVAASFFARA	KIF26B	376	Q2KJY2
RTTLFSAAFSLSGSL	GPR137C	96	Q8N3F9
SLRLSCAASGFTFSS	IGHV3-13	36	P01766
RSSSTESFGLFSCLV	MAPK8IP2	586	Q13387
AGRIASTSFSTCEFL	FAM177B	71	A6PVY3
STSFSTCEFLGGRFA	FAM177B	76	A6PVY3
SLRLSCAASGFTFSS	IGHV3-48	36	P01763
ASSIASASTFFGGSR	PTGER1	266	P34995
GTLFYESSSSICRAA	CRISPLD2	321	Q9H0B8
LASFSFTSACTFICS	SELL	276	P14151
SSRMSFRSSFASLFS	EXPH5	116	Q8NEV8
FGSTSLCFDSRQRSA	EXPH5	316	Q8NEV8
SFDSDCSLRALASGS	KIF26A	1056	Q9ULI4
SLRLSCSASGFTFSS	IGHV3-64D	36	A0A0J9YX35
ARSFSACSVGLGRSS	KRT35	46	Q92764
SLRLSCAASGFTFSS	IGHV3-74	36	A0A0B4J1X5
FTFTTESCFSDRGSL	CDC42BPB	401	Q9Y5S2
SLRLSCTASGFTFGD	IGHV3-49	36	A0A0A0MS15
SLRLSCAASGFTFSS	IGHV3-21	36	A0A0B4J1V1
SSSSSRDSGAIASFL	INSM2	336	Q96T92
CSSHLSVVSLFFGTS	OR1G1	241	P47890
LFLGSLAFADACTSS	OR5AC1	61	P0C628
ALSRCSQLSTFSFCG	PRAMEF12	371	O95522
ASRFFSSCFGIVSTL	GPR135	186	Q8IZ08
GGSSSKRFLRSCSAS	ABL1	706	P00519
ASGSRNFSSCSAEDF	ADAM9	376	Q13443
SLGARSASLRSFSSD	ANK3	906	Q12955
SLRLSCAASGFTFSS	IGHV3-23	36	P01764
SLRLSCAASGFTFSS	IGHV3-30	36	P01768
SRSFSCLNRSLSSGE	MAST4	1281	O15021
FFSVATSGCSAAAAS	ITLN2	16	Q8WWU7
KRALASNTSFFSGCS	KIF4A	1211	O95239
SLRLSCAASGFTFSN	IGHV3-16	36	A0A0C4DH30
VLSRCSQLSTFSFCG	PRAMEF8	371	Q5VWM4
RNLSTCFSSGDLFTA	SLC39A14	86	Q15043
GSFNSRICSLSSSLY	SLFN13	121	Q68D06
CSLFSAAGSLSVFAS	MFSD13A	166	Q14CX5
RRLCATGTADSTFSA	PKD1L1	156	Q8TDX9
SLRLSCAASGFTFSS	IGHV3-33	36	P01772
SLRLSCAASGFTVSS	IGHV3-53	36	P01767
SLRLSCAASGFTFSN	IGHV3-35	36	A0A0C4DH35
SLKLSCAASGFTFSG	IGHV3-73	36	A0A0B4J1V6
VNSHLTSSFCRGLFS	NLRP3	721	Q96P20
TSSFCRGLFSVLSTS	NLRP3	726	Q96P20
YSTRFLADSSGLLSC	TAF5L	346	O75529
SFLLGSSASLDCGFS	TAPBPL	201	Q9BX59
SSSSIFSRSALSICA	TMEM151B	441	Q8IW70
RGLSSTTCSFSANAD	NBPF6	531	Q5VWK0
SLFQTFSISCSLSRS	SLC26A5	386	P58743
AASLCSFSSSRSGFH	RHBDF1	186	Q96CC6
LSRANSSSFSSGESC	SIPA1L2	426	Q9P2F8
LSSVFALCLGHTSSF	SLC17A9	321	Q9BYT1
FAGSRSITECSSFSS	SVEP1	1151	Q4LDE5
DSAFSSRGSLSLSFE	RIPK4	426	P57078
GTRSRFFCSSDSTDC	EXO1	501	Q9UQ84
ASARASLVSSSDGSF	ROBO4	886	Q8WZ75
VLSRCSQLSTFSFCG	PRAMEF7	371	Q5VXH5
SFSHTLVSLSLFGCT	ZER1	126	Q7Z7L7
SECGKSFSFRSSFSQ	ZNF135	301	P52742
SSSSGFLDLFFSHCR	UGT1A10	111	Q9HAW8
STARCSLFGSDFVNT	VWF	31	P04275
VTLASGSRCFSFLSV	SPHK2	321	Q9NRA0
GFFSCFVATTALSRT	SLC26A4	396	O43511
NASFGCAVSTSASFS	TRO	1066	Q12816
FFDSRTLGSLTLSSS	TBX18	586	O95935
FFLATASLAGSSSSF	UNQ6494/PRO21346	16	Q6UXR6
SSNLTTLFRRSCFTG	TCTN2	191	Q96GX1
NSGSEACTSSFLRLS	ZNF106	1301	Q9H2Y7
ACTSSFLRLSFASET	ZNF106	1306	Q9H2Y7
RLGSLDCSHSFSSRT	TNRC6A	1881	Q8NDV7
LSPVSLSSGCLSFSF	ZAN	276	Q9Y493
FSASSARRFSSGLFN	PPP1R12B	411	O60237