Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	transcription elongation factor complex	CCNT2 AFF1 PAF1	1.55e-04	56	39	3	GO:0008023
Domain	DUF4599	SPATA31D4 SPATA31D3	2.91e-04	12	40	2	PF15371
Domain	DUF4599	SPATA31D4 SPATA31D3	2.91e-04	12	40	2	IPR027970
Domain	Homeobox	HOXA11 SIX4 UNCX NOBOX	1.54e-03	234	40	4	PF00046
Domain	HOMEOBOX_1	HOXA11 SIX4 UNCX NOBOX	1.59e-03	236	40	4	PS00027
Domain	HOX	HOXA11 SIX4 UNCX NOBOX	1.61e-03	237	40	4	SM00389
Domain	Homeobox_dom	HOXA11 SIX4 UNCX NOBOX	1.66e-03	239	40	4	IPR001356
Domain	HOMEOBOX_2	HOXA11 SIX4 UNCX NOBOX	1.66e-03	239	40	4	PS50071
Domain	-	HOXA11 SIX4 UNCX NOBOX	3.07e-03	283	40	4	1.10.10.60
Domain	WW	MAGI2 DGCR8	4.55e-03	47	40	2	PF00397
Domain	WW	MAGI2 DGCR8	4.74e-03	48	40	2	SM00456
Domain	WW_DOMAIN_2	MAGI2 DGCR8	5.34e-03	51	40	2	PS50020
Domain	WW_DOMAIN_1	MAGI2 DGCR8	5.34e-03	51	40	2	PS01159
Domain	Homeodomain-like	HOXA11 SIX4 UNCX NOBOX	5.41e-03	332	40	4	IPR009057
Domain	WW_dom	MAGI2 DGCR8	5.54e-03	52	40	2	IPR001202
Domain	Homeobox_CS	HOXA11 SIX4 UNCX	7.33e-03	186	40	3	IPR017970
Domain	-	PSD3 DOCK10 MTMR7 FRMD6	9.54e-03	391	40	4	2.30.29.30
Domain	PH_dom-like	PSD3 DOCK10 MTMR7 FRMD6	1.28e-02	426	40	4	IPR011993
Pubmed	PMS2 or PMS2CL? Characterization of variants detected in the 3' of the PMS2 gene.	PMS2 PMS2CL	1.42e-06	2	42	2	37534630
Pubmed	The prognostic relevance of FOXA1 and Nestin expression in breast cancer metastases: a retrospective study of 164 cases during a 10-year period (2004-2014).	NES FOXA1	1.42e-06	2	42	2	30819139
Pubmed	Reclassification of a frequent African-origin variant from PMS2 to the pseudogene PMS2CL.	PMS2 PMS2CL	1.42e-06	2	42	2	31916644
Pubmed	Mismatch repair gene PMS2: disease-causing germline mutations are frequent in patients whose tumors stain negative for PMS2 protein, but paralogous genes obscure mutation detection and interpretation.	PMS2 PMS2CL	1.42e-06	2	42	2	15256438
Pubmed	Coactivators for the orphan nuclear receptor RORalpha.	NCOA2 RORA	4.27e-06	3	42	2	10478845
Pubmed	Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease.	NCOA2 RORA	4.27e-06	3	42	2	19039140
Pubmed	The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development.	NHLH2 SP8 FOXA1	5.25e-06	28	42	3	32868762
Pubmed	The microRNA cluster miR-17∼92 promotes TFH cell differentiation and represses subset-inappropriate gene expression.	RORA DGCR8	8.53e-06	4	42	2	23812098
Pubmed	Lgl1 Is Required for Olfaction and Development of Olfactory Bulb in Mice.	SP8 NES	8.53e-06	4	42	2	27603780
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PSD3 DOCK10 MAGI2 CEP192 ADCY3 MARK4	9.09e-06	407	42	6	12693553
Pubmed	Differential expression of alpha-E-catenin and alpha-N-catenin in the developing cerebral cortex.	NES CTNNA2	1.42e-05	5	42	2	16457793
Pubmed	A Distinct Inhibitory Function for miR-18a in Th17 Cell Differentiation.	RORA DGCR8	1.42e-05	5	42	2	28607111
Pubmed	Cloning and characterization of four murine homeobox genes.	UNCX NOBOX	1.42e-05	5	42	2	8855241
Pubmed	Paired-related murine homeobox gene expressed in the developing sclerotome, kidney, and nervous system.	PMS2 UNCX	1.42e-05	5	42	2	9286595
Pubmed	Dynamic spatiotemporal gene expression in embryonic mouse thalamus.	NHLH2 NES RORA	1.69e-05	41	42	3	21192082
Pubmed	Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.	AFF1 CTNNA2 MYO16	3.68e-05	53	42	3	23535033
Pubmed	NKCC1-Deficiency Results in Abnormal Proliferation of Neural Progenitor Cells of the Lateral Ganglionic Eminence.	SP8 NES	3.97e-05	8	42	2	27582690
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	HOXA11 NHLH2 SP8 SIX4 UNCX FOXA1	4.63e-05	544	42	6	28473536
Pubmed	Transcriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cure.	AFF1 PAF1	5.10e-05	9	42	2	24565118
Pubmed	E-Cadherin regulates neural stem cell self-renewal.	NES CTNNA2	6.37e-05	10	42	2	19321785
Pubmed	Alpha N-catenin deficiency causes defects in axon migration and nuclear organization in restricted regions of the mouse brain.	NES CTNNA2	6.37e-05	10	42	2	16691566
Pubmed	Neural stem cell self-renewal requires the Mrj co-chaperone.	NHLH2 NES	7.78e-05	11	42	2	19777589
Pubmed	HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP.	AFF1 PAF1	7.78e-05	11	42	2	20471949
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	PSD3 DOCK10 CTNNA2 FRMD6 ADCY3	8.92e-05	377	42	5	38117590
Pubmed	Transcriptional profiling of Wnt3a mutants identifies Sp transcription factors as essential effectors of the Wnt/β-catenin pathway in neuromesodermal stem cells.	SP8 UNCX	9.32e-05	12	42	2	24475213
Pubmed	A census of human transcription factors: function, expression and evolution.	HOXA11 NHLH2 RORA SIX4 UNCX FOXA1 NOBOX	9.82e-05	908	42	7	19274049
Pubmed	Breaking constraint of mammalian axial formulae.	HOXA11 UNCX	1.10e-04	13	42	2	35017475
Pubmed	Transcriptional and posttranscriptional regulation of HIV-1 gene expression.	AFF1 PAF1	1.10e-04	13	42	2	22355797
Pubmed	MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.	CCNT2 AFF1	1.28e-04	14	42	2	20854876
Pubmed	The zinc finger transcription factor Sp8 regulates the generation and diversity of olfactory bulb interneurons.	SP8 NES	1.28e-04	14	42	2	16476661
Pubmed	Deficits in microRNA-mediated Cxcr4/Cxcl12 signaling in neurodevelopmental deficits in a 22q11 deletion syndrome mouse model.	NES DGCR8	1.28e-04	14	42	2	24101523
Pubmed	Differential regulation of telencephalic pallial-subpallial boundary patterning by Pax6 and Gsh2.	SP8 NES	1.28e-04	14	42	2	18701439
Pubmed	Transcriptional elongation factor ENL phosphorylated by ATM recruits polycomb and switches off transcription for DSB repair.	AFF1 PAF1	1.28e-04	14	42	2	25921070
Pubmed	MicroRNA-independent functions of DGCR8 are essential for neocortical development and TBR1 expression.	NES DGCR8	1.28e-04	14	42	2	28232627
Pubmed	Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis.	NES UNCX	1.28e-04	14	42	2	26728556
Pubmed	Retinoic acid promotes limb induction through effects on body axis extension but is unnecessary for limb patterning.	HOXA11 UNCX	1.48e-04	15	42	2	19464179
Pubmed	Hippocampals neurogenesis is impaired in mice with a deletion in the coiled coil domain of Talpid3-implications for Joubert syndrome.	NES ADCY3	1.48e-04	15	42	2	35470378
Pubmed	Tbx6-dependent Sox2 regulation determines neural or mesodermal fate in axial stem cells.	UNCX FOXA1	1.48e-04	15	42	2	21331042
Pubmed	Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are essential for Notch signaling in vivo.	NES UNCX	1.69e-04	16	42	2	22069191
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	PCNX2 NCOA2 SPATA31D4 SPATA31D3	1.80e-04	233	42	4	37704626
Pubmed	The DNA sequence of human chromosome 7.	MAGI2 HOXA11 PMS2 UNCX NOBOX	1.85e-04	441	42	5	12853948
Pubmed	Nova2 regulates neuronal migration through an RNA switch in disabled-1 signaling.	NES CTNNA2	1.91e-04	17	42	2	20620871
Pubmed	Hox patterning of the vertebrate rib cage.	HOXA11 FOXA1	1.91e-04	17	42	2	17626057
Pubmed	Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.	NCOA2 FOXA1	1.91e-04	17	42	2	19183483
Pubmed	RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways.	NCOA2 RORA	2.15e-04	18	42	2	14687547
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PSD3 PMS2 MTMR7 CEP192 CKAP4 SIX4 PAF1	2.39e-04	1049	42	7	27880917
Pubmed	alphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway.	NES CTNNA2	2.40e-04	19	42	2	16543460
Pubmed	Lunatic fringe potentiates Notch signaling in the developing brain.	NES RORA	2.40e-04	19	42	2	20510365
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	PEX14 NES IRF2BPL PMS2 SIX4	2.53e-04	472	42	5	38943005
Pubmed	A key role for the HLH transcription factor EBF2COE2,O/E-3 in Purkinje neuron migration and cerebellar cortical topography.	NES RORA	2.67e-04	20	42	2	16774995
Pubmed	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	MAGI2 FRMD6	2.67e-04	20	42	2	19668339
Pubmed	Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling.	NES FOXA1	2.67e-04	20	42	2	28154153
Pubmed	Loss of BAF Complex in Developing Cortex Perturbs Radial Neuronal Migration in a WNT Signaling-Dependent Manner.	NES CTNNA2	2.67e-04	20	42	2	34220450
Pubmed	Uncx regulates proliferation of neural progenitor cells and neuronal survival in the olfactory epithelium.	UNCX ADCY3	2.95e-04	21	42	2	20692344
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	PEX14 CEP192 DGCR8 FRMD6 RPS3A CCDC186	3.22e-04	777	42	6	35844135
Pubmed	Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.	DGCR8 CTNNA2 CKAP4	3.23e-04	110	42	3	27889896
Pubmed	Independent regulation of vertebral number and vertebral identity by microRNA-196 paralogs.	HOXA11 UNCX	3.24e-04	22	42	2	26283362
Pubmed	The Role of RNA Polymerase II Elongation Control in HIV-1 Gene Expression, Replication, and Latency.	AFF1 PAF1	3.24e-04	22	42	2	22567366
Pubmed	Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells.	NCOA2 FOXA1	3.54e-04	23	42	2	19737349
Pubmed	Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling.	NES ADCY3	3.54e-04	23	42	2	18728187
Pubmed	Repression of Fgf signaling by sprouty1-2 regulates cortical patterning in two distinct regions and times.	SP8 NES	3.86e-04	24	42	2	20237272
Pubmed	Gene network analysis in a pediatric cohort identifies novel lung function genes.	PSD3 MYO16	3.86e-04	24	42	2	24023788
Pubmed	Presenilin 1 in migration and morphogenesis in the central nervous system.	NES RORA	4.20e-04	25	42	2	15163631
Pubmed	Sp8 controls the anteroposterior patterning at the midbrain-hindbrain border.	SP8 NES	4.20e-04	25	42	2	16571633
Pubmed	A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney.	HOXA11 FOXA1	4.54e-04	26	42	2	19060336
Pubmed	Olig1 function is required to repress dlx1/2 and interneuron production in Mammalian brain.	SP8 NES	4.54e-04	26	42	2	24507192
Pubmed	Cerebellar dysfunction and schizophrenia-like behavior in Ebp1-deficient mice.	NES RORA	4.54e-04	26	42	2	35165395
Pubmed	Compartment-dependent activities of Wnt3a/β-catenin signaling during vertebrate axial extension.	UNCX FOXA1	4.90e-04	27	42	2	25152336
Pubmed	Specification of jaw identity by the Hand2 transcription factor.	SIX4 UNCX	5.28e-04	28	42	2	27329940
Pubmed	ISL1 is necessary for auditory neuron development and contributes toward tonotopic organization.	NHLH2 UNCX	5.28e-04	28	42	2	36074819
Pubmed	Molecular architecture of the developing mouse brain.	NHLH2 SP8 FOXA1	5.51e-04	132	42	3	34321664
Pubmed	Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells.	RORA FOXA1	6.06e-04	30	42	2	25804738
Pubmed	Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation.	RORA FOXA1	6.47e-04	31	42	2	36476860
Pubmed	ΔNp63α Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas.	NES SIX4 PAF1	6.81e-04	142	42	3	30232004
Pubmed	Dgcr8 functions in the secondary heart field for outflow tract and right ventricle development in mammals.	DGCR8 SIX4	6.90e-04	32	42	2	38110169
Pubmed	Mind bomb 1 is essential for generating functional Notch ligands to activate Notch.	NES UNCX	7.34e-04	33	42	2	16000382
Pubmed	A protein interaction landscape of breast cancer.	PMS2 CTNNA2 HEATR6 FOXA1 FRMD6	9.65e-04	634	42	5	34591612
Pubmed	Defining the molecular character of the developing and adult kidney podocyte.	MAGI2 NES	1.03e-03	39	42	2	21931791
Pubmed	Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain.	NES CTNNA2	1.03e-03	39	42	2	22802532
Pubmed	Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1.	IRF2BPL FOXA1	1.08e-03	40	42	2	34585037
Pubmed	The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning.	HOXA11 UNCX	1.08e-03	40	42	2	21256124
Pubmed	A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis.	RORA BRWD1	1.13e-03	41	42	2	23509962
Pubmed	Ranbp1, Deleted in DiGeorge/22q11.2 Deletion Syndrome, is a Microcephaly Gene That Selectively Disrupts Layer 2/3 Cortical Projection Neuron Generation.	NES DGCR8	1.13e-03	41	42	2	25452572
Pubmed	SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.	NES CKAP4 RPS3A	1.20e-03	173	42	3	23979707
Cytoband	9q21.32	SPATA31D4 SPATA31D3	1.38e-04	19	42	2	9q21.32
Cytoband	Ensembl 112 genes in cytogenetic band chr7p22	PMS2 UNCX PMS2CL	2.57e-04	134	42	3	chr7p22
Cytoband	Ensembl 112 genes in cytogenetic band chr8p22	PSD3 MTMR7	8.60e-04	47	42	2	chr8p22
GeneFamily	PRD class homeoboxes and pseudogenes	UNCX NOBOX	8.88e-03	92	28	2	521
GeneFamily	Basic helix-loop-helix proteins	NCOA2 NHLH2	1.25e-02	110	28	2	420
Coexpression	ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF	PSD3 AFF1 RORA IRF2BPL FOXA1 FRMD6	1.35e-06	232	40	6	M2613
Coexpression	GSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_UP	DOCK10 CCNT2 RORA DGCR8 BRWD1	1.27e-05	199	40	5	M3046
Coexpression	LAKE_ADULT_KIDNEY_C21_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_B	PSD3 NCOA2 RORA RALGAPA2	1.84e-05	103	40	4	M39240
Coexpression	MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_29	HOXA11 PMS2	6.32e-05	8	40	2	M762
Coexpression	NAKAYA_B_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_DN	PSD3 NCOA2 PMS2 DGCR8 PMS2CL	8.19e-05	294	40	5	M41112
Coexpression	GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_UP	NCOA2 DOCK10 RALGAPA2 BRWD1	1.24e-04	168	40	4	M6874
Coexpression	LAKE_ADULT_KIDNEY_C11_THIN_ASCENDING_LIMB	NCOA2 AFF1 RALGAPA2 BRWD1	1.27e-04	169	40	4	M39230
Coexpression	MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_UP	MAGI2 CTNNA2 BRWD1	1.54e-04	68	40	3	M11763
Coexpression	GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_AND_IL4_STIM_UP	IRF2BPL DGCR8 CKAP4 MARK4	2.38e-04	199	40	4	M8002
Coexpression	GSE17721_CTRL_VS_CPG_4H_BMDC_DN	HOXA11 AFF1 FRMD6 MARK4	2.42e-04	200	40	4	M3763
Coexpression	GSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDC_DN	NCOA2 MTMR7 FRMD6 ADCY3	2.42e-04	200	40	4	M3779
Coexpression	GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_DN	CCNT2 HEATR6 RPS3A BRWD1	2.42e-04	200	40	4	M5529
Coexpression	GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_DN	DOCK10 CCNT2 IRF2BPL BRWD1	2.42e-04	200	40	4	M8088
Coexpression	GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_UP	PSD3 HSH2D IRF2BPL CEP192	2.42e-04	200	40	4	M7841
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	RORA SIX4 MYO16 MARK4	1.84e-05	167	42	4	9efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCell	Cerebellum-Neuronal-Inhibitory\|Cerebellum / BrainAtlas - Mouse McCarroll V32	RORA SIX4 MYO16 MARK4	1.84e-05	167	42	4	904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PSD3 DOCK10 NES ADCY3	1.97e-05	170	42	4	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_GRIP2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 SP8 NES MYO16	2.21e-05	175	42	4	0c648e7f67ffbe3b476a2ca77d246554f8cd1882
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PSD3 DOCK10 MAGI2 RORA	3.37e-05	195	42	4	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Meis2-Meis2_Adamts19\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	HOXA11 SP8 MYO16	3.63e-05	68	42	3	3a61ea2b234829632fabede72761aa6664550e56
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Meis2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	HOXA11 SP8 MYO16	3.63e-05	68	42	3	3c5d0d35e4d1c5506a4a490e2f93e8024294207f
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	PSD3 MAGI2 RPS3A CCDC186	3.64e-05	199	42	4	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	NCOA2 MAGI2 AFF1 RORA	3.64e-05	199	42	4	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	PSD3 MAGI2 RPS3A CCDC186	3.64e-05	199	42	4	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
Disease	urate measurement, bone density	PSD3 PEX14 CTNNA2 HEATR6 MYO16 MARK4	1.30e-04	619	38	6	EFO_0003923, EFO_0004531
Disease	cystathionine measurement	PSD3 CTNNA2	2.72e-04	19	38	2	EFO_0010474
Disease	Alzheimer disease, APOE carrier status	RORA PMS2 PMS2CL	2.75e-04	98	38	3	EFO_0007659, MONDO_0004975
Disease	sex interaction measurement, bilirubin measurement	PSD3 FRMD6	3.67e-04	22	38	2	EFO_0004570, EFO_0008343
Disease	triglyceride measurement, intermediate density lipoprotein measurement	PSD3 AFF1 BRWD1	3.97e-04	111	38	3	EFO_0004530, EFO_0008595
Disease	immature platelet fraction	PSD3 DOCK10 MARK4	4.29e-04	114	38	3	EFO_0009187
Disease	age at menopause	NCOA2 DOCK10 CCNT2 NOBOX	6.04e-04	302	38	4	EFO_0004704
Disease	C-reactive protein measurement	PSD3 PEX14 RORA CEP192 RPS3A ADCY3 MARK4	7.77e-04	1206	38	7	EFO_0004458
Disease	Stuttering	RORA CTNNA2 FRMD6	8.30e-04	143	38	3	HP_0025268
Disease	triglyceride measurement, physical activity	PSD3 AFF1	8.83e-04	34	38	2	EFO_0003940, EFO_0004530
Disease	multiple sclerosis	NCOA2 DOCK10 AFF1 RORA ADCY3	9.42e-04	594	38	5	MONDO_0005301
Disease	low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	PSD3 AFF1 RORA	1.01e-03	153	38	3	EFO_0004611, EFO_0020946
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	PSD3 AFF1 BRWD1	1.28e-03	166	38	3	EFO_0004530, EFO_0004611
Disease	ejection fraction measurement	PMS2 PMS2CL	1.41e-03	43	38	2	EFO_0005527
Disease	Abnormality of refraction	MAGI2 AFF1 PEX14 RORA CTNNA2	1.64e-03	673	38	5	HP_0000539
Disease	caudate nucleus measurement, functional brain measurement, response to reward	PSD3 MYO16	1.68e-03	47	38	2	EFO_0007849, EFO_0008387, EFO_0008396
Disease	breast carcinoma	PEX14 RORA IRF2BPL CEP192 CTNNA2 ADCY3	1.79e-03	1019	38	6	EFO_0000305
Disease	response to trauma exposure	NCOA2 RORA	1.98e-03	51	38	2	EFO_0008483
Disease	polyunsaturated fatty acids to monounsaturated fatty acids ratio	PSD3 AFF1	1.98e-03	51	38	2	EFO_0022302
Disease	cholesterol to total lipids in small HDL percentage	PSD3 AFF1	1.98e-03	51	38	2	EFO_0022240
Disease	free cholesterol to total lipids in small LDL percentage	PSD3 AFF1	2.14e-03	53	38	2	EFO_0022286
Disease	triglycerides in very large HDL measurement	PSD3 UNCX	2.30e-03	55	38	2	EFO_0022324
Disease	fatty acid measurement	PSD3 AFF1 CTNNA2 BRWD1	2.33e-03	436	38	4	EFO_0005110
Disease	triglycerides in LDL measurement	PSD3 AFF1	2.38e-03	56	38	2	EFO_0022320
Disease	triglycerides in chylomicrons and extremely large VLDL measurement	PSD3 AFF1	2.38e-03	56	38	2	EFO_0022316
Disease	triglycerides in IDL measurement	PSD3 AFF1	2.55e-03	58	38	2	EFO_0022149
Disease	severe acute respiratory syndrome, COVID-19	PSD3 NCOA2 MAGI2 PMS2	2.55e-03	447	38	4	EFO_0000694, MONDO_0100096
Disease	triglycerides to total lipids in small LDL percentage	PSD3 AFF1	2.64e-03	59	38	2	EFO_0022337
Disease	cholesteryl esters to total lipids in large HDL percentage	PSD3 AFF1	2.64e-03	59	38	2	EFO_0022248
Disease	concentration of chylomicrons and extremely large VLDL particles measurement	PSD3 AFF1	2.64e-03	59	38	2	EFO_0022260
Disease	basophil measurement	AFF1 CKAP4	2.73e-03	60	38	2	EFO_0803539
Disease	cholesterol in chylomicrons and extremely large VLDL measurement	PSD3 AFF1	2.73e-03	60	38	2	EFO_0021898
Disease	very low density lipoprotein cholesterol measurement, lipid measurement	PSD3 AFF1 BRWD1	2.85e-03	220	38	3	EFO_0004529, EFO_0008317
Disease	triglycerides in medium LDL measurement	PSD3 AFF1	2.91e-03	62	38	2	EFO_0022322
Disease	total lipids in chylomicrons and extremely large VLDL measurement	PSD3 AFF1	2.91e-03	62	38	2	EFO_0022306
Disease	free cholesterol in chylomicrons and extremely large VLDL measurement	PSD3 AFF1	2.91e-03	62	38	2	EFO_0022263
Disease	free cholesterol to total lipids in medium LDL percentage	PSD3 AFF1	3.00e-03	63	38	2	EFO_0022283
Disease	phospholipids in chylomicrons and extremely large VLDL measurement	PSD3 AFF1	3.00e-03	63	38	2	EFO_0022292
Disease	very low density lipoprotein cholesterol measurement, phospholipid measurement	PSD3 AFF1 BRWD1	3.19e-03	229	38	3	EFO_0004639, EFO_0008317
Disease	triglycerides in small LDL measurement	PSD3 AFF1	3.19e-03	65	38	2	EFO_0022323
Disease	Bipolar Disorder	MAGI2 SP8 RORA ADCY3	3.22e-03	477	38	4	C0005586
Disease	Alzheimer disease	AFF1 CTNNA2 MYO16 MARK4	3.42e-03	485	38	4	MONDO_0004975
Disease	smoking status measurement	MAGI2 SP8 IRF2BPL CTNNA2 ADCY3 BRWD1	3.42e-03	1160	38	6	EFO_0006527
Disease	triglycerides in very small VLDL measurement	PSD3 AFF1	3.49e-03	68	38	2	EFO_0022144
Disease	Nonorganic psychosis	SP8 DGCR8	3.59e-03	69	38	2	C0349204
Disease	basophil percentage of leukocytes	NCOA2 AFF1 CKAP4	3.76e-03	243	38	3	EFO_0007992
Disease	mean arterial pressure	DOCK10 HOXA11 CCNT2 MARK4	3.78e-03	499	38	4	EFO_0006340

Protein segments in the cluster

Peptide	Gene	Start	Entry
PDHGGGEDSCAKTDT	CCDC186	71	Q7Z3E2
SSSDEGSGKSKHSSP	CCNT2	536	O60583
GSSSGGSKHSADGIP	CCNT2	581	O60583
ASPSEKGAHPSGGAD	CKAP4	16	Q07065
KYGGDSDHPSDGETS	DGCR8	266	Q8WYQ5
DVAGSDSSHKDGPCG	NOBOX	471	O60393
PESSEHEDKSAGASG	MAGI2	251	Q86UL8
SGGEHAPSEDSGKDR	MTMR7	636	Q9Y216
KEGADPHTLVSSGGS	MYO16	81	Q9Y6X6
ADTLGTAHSPKDGSS	IRF2BPL	631	Q9H1B7
GSGEGGNAIKDHSSS	PCNX2	471	A6NKB5
KSGAEGDDTGAPHSP	HEATR6	1111	Q6AI08
SPDHSSLEAKDGESG	NES	471	P48681
SPESSSGHTEDKAGG	HOXA11	221	P31270
GGGPTEQDKSHSNSS	RALGAPA2	351	Q2PPJ7
GTGKGSQDHSGDPTS	HSH2D	246	Q96JZ2
DHSGATATGGASELK	FOXA1	336	P55317
GSSSEKEGSEDEHSG	PAF1	401	Q8N7H5
GSSHTSGVESGGKDR	FRMD6	431	Q96NE9
KDEDTTSHSSSKGGG	DOCK10	161	Q96BY6
TSPTDEAKGHTGIGE	CTNNA2	261	P26232
GSAHSSGSTSEKPEE	ADCY3	536	O60266
SSGEDSKSHIPGSET	BRWD1	2051	Q9NSI6
DTHGTLGSGRSSDKG	MARK4	16	Q96L34
LESTSDLGASGKHGG	CEP192	2081	Q8TEP8
GSGDSDSESDHTAPS	DVL1P1	571	P54792
KTPGAGESSEDNSDH	SNX29P2	131	Q8IUI4
LHGEGSSSGKATGDE	RPS3A	231	P61247
SAHSDPESLGGTDTK	NHLH2	16	Q02577
DGNPSTEDESSKGHE	SIX4	291	Q9UIU6
GGSSTSAPTTKGIDH	SPATA31D4	331	Q6ZUB0
STSSSPGKEGHSPEG	PEX14	271	O75381
KGSDTDSEHSAAGSP	SP8	456	Q8IXZ3
SFGGETSNSGDPHKG	AKAP3	66	O75969
KGSRSSSEHKGSSGD	AFF1	921	P51825
KDSTGSLPGSGSTHG	NCOA2	666	Q15596
GGSSTSAPTTKGIDH	SPATA31D3	331	P0C874
GHTPEGSKADSAVSS	RORA	206	P35398
EKDSGHGSTSVDSEG	PMS2	491	P54278
KDSGHGSTSVDSEGF	PMS2CL	106	Q68D20
GSGKSNVGTSGDHDD	POTEH	111	Q6S545
SEGKAPDTSDHGGST	PSD3	36	Q9NYI0
SLHSAPSSDSDSGGG	UNCX	226	A6NJT0