Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	purine deoxyribonucleotide binding	SAMHD1 HSP90AA1 HSP90AB1	2.06e-06	7	79	3	GO:0032554
GeneOntologyMolecularFunction	deoxyribonucleotide binding	SAMHD1 HSP90AA1 HSP90AB1	4.92e-06	9	79	3	GO:0032552
GeneOntologyMolecularFunction	ATP hydrolysis activity	DNAH3 ERCC2 KIF28P HSP90AB2P DNAH5 SNRNP200 ABCA10 HSP90AA1 HSP90AB1 HSP90AB3P	9.22e-06	441	79	10	GO:0016887
GeneOntologyMolecularFunction	unfolded protein binding	UBE4B HSP90AB2P HSP90AA1 TBCE HSP90AB1 HSP90AB3P	1.07e-05	126	79	6	GO:0051082
GeneOntologyMolecularFunction	CTP binding	HSP90AA1 HSP90AB1	1.55e-05	2	79	2	GO:0002135
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	UBR2 UBE4B UBE3A ASB4 HERC3 UBE3C HERC4 PCGF5 FBXW7	1.60e-05	372	79	9	GO:0061630
GeneOntologyMolecularFunction	disordered domain specific binding	HSP90AB2P HSP90AA1 HSP90AB1 HSP90AB3P	1.68e-05	39	79	4	GO:0097718
GeneOntologyMolecularFunction	ATP-dependent protein folding chaperone	HSP90AB2P HSP90AA1 HSP90AB1 HSP90AB3P	1.86e-05	40	79	4	GO:0140662
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	UBR2 UBE4B UBE3A ASB4 HERC3 UBE3C HERC4 PCGF5 FBXW7	2.73e-05	398	79	9	GO:0061659
GeneOntologyMolecularFunction	ATP-dependent activity	DNAH3 ERCC2 KIF28P HSP90AB2P DNAH5 SNRNP200 ABCA10 HSP90AA1 SLC27A2 HSP90AB1 HSP90AB3P	2.88e-05	614	79	11	GO:0140657
GeneOntologyMolecularFunction	sulfonylurea receptor binding	HSP90AA1 HSP90AB1	4.62e-05	3	79	2	GO:0017098
GeneOntologyMolecularFunction	5-methylcytosine dioxygenase activity	TET2 TET3	4.62e-05	3	79	2	GO:0070579
GeneOntologyMolecularFunction	UTP binding	HSP90AA1 HSP90AB1	9.23e-05	4	79	2	GO:0002134
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	UBR2 UBE4B UBE3A ASB4 HERC3 UBE3C HERC4 PCGF5 FBXW7	1.03e-04	473	79	9	GO:0004842
GeneOntologyMolecularFunction	pyrimidine ribonucleotide binding	HSP90AA1 HSP90AB1	1.53e-04	5	79	2	GO:0032557
GeneOntologyMolecularFunction	dATP binding	HSP90AA1 HSP90AB1	1.53e-04	5	79	2	GO:0032564
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	UBR2 UBE4B UBE3A ASB4 HERC3 UBE3C HERC4 PCGF5 FBXW7	1.87e-04	512	79	9	GO:0019787
GeneOntologyMolecularFunction	protein folding chaperone	HSP90AB2P HSP90AA1 HSP90AB1 HSP90AB3P	2.01e-04	73	79	4	GO:0044183
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	DNAH3 ERCC2 KIF28P HSP90AB2P DNAH5 GTPBP10 SNRNP200 ABCA10 HSP90AA1 HSP90AB1 HSP90AB3P	2.28e-04	775	79	11	GO:0017111
GeneOntologyMolecularFunction	adenyl deoxyribonucleotide binding	HSP90AA1 HSP90AB1	2.29e-04	6	79	2	GO:0032558
GeneOntologyMolecularFunction	histone H2A ubiquitin ligase activity	UBR2 PCGF5	2.29e-04	6	79	2	GO:0141053
GeneOntologyMolecularFunction	aminoacyltransferase activity	UBR2 UBE4B UBE3A ASB4 HERC3 UBE3C HERC4 PCGF5 FBXW7	2.48e-04	532	79	9	GO:0016755
GeneOntologyMolecularFunction	TPR domain binding	HSP90AA1 HSP90AB1	4.26e-04	8	79	2	GO:0030911
GeneOntologyMolecularFunction	pyrophosphatase activity	DNAH3 ERCC2 KIF28P HSP90AB2P DNAH5 GTPBP10 SNRNP200 ABCA10 HSP90AA1 HSP90AB1 HSP90AB3P	4.48e-04	839	79	11	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	DNAH3 ERCC2 KIF28P HSP90AB2P DNAH5 GTPBP10 SNRNP200 ABCA10 HSP90AA1 HSP90AB1 HSP90AB3P	4.53e-04	840	79	11	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	DNAH3 ERCC2 KIF28P HSP90AB2P DNAH5 GTPBP10 SNRNP200 ABCA10 HSP90AA1 HSP90AB1 HSP90AB3P	4.53e-04	840	79	11	GO:0016818
GeneOntologyMolecularFunction	nitric-oxide synthase regulator activity	HSP90AA1 HSP90AB1	6.81e-04	10	79	2	GO:0030235
GeneOntologyMolecularFunction	pyrimidine nucleotide binding	HSP90AA1 HSP90AB1	8.31e-04	11	79	2	GO:0019103
GeneOntologyMolecularFunction	1-phosphatidylinositol-3-kinase activity	PIK3C3 ATM	8.31e-04	11	79	2	GO:0016303
GeneOntologyMolecularFunction	ATPase binding	UBE4B PEX19 SNTA1 VCPKMT	8.90e-04	108	79	4	GO:0051117
GeneOntologyMolecularFunction	acyltransferase activity	UBR2 CASD1 UBE4B UBE3A ASB4 HERC3 UBE3C HERC4 PCGF5 FBXW7	9.37e-04	775	79	10	GO:0016746
GeneOntologyMolecularFunction	histone ubiquitin ligase activity	UBR2 PCGF5	9.94e-04	12	79	2	GO:0140852
GeneOntologyMolecularFunction	2-oxoglutarate-dependent dioxygenase activity	TET2 PLOD2 TET3	2.18e-03	65	79	3	GO:0016706
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH3 DNAH5	2.27e-03	18	79	2	GO:0008569
GeneOntologyMolecularFunction	microtubule motor activity	DNAH3 KIF28P DNAH5	2.70e-03	70	79	3	GO:0003777
GeneOntologyMolecularFunction	DNA polymerase binding	HSP90AA1 HSP90AB1	3.70e-03	23	79	2	GO:0070182
GeneOntologyMolecularFunction	phosphatidylinositol kinase activity	PIK3C3 ATM	4.72e-03	26	79	2	GO:0052742
GeneOntologyMolecularFunction	MHC class II protein complex binding	HSP90AA1 HSP90AB1	5.09e-03	27	79	2	GO:0023026
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH3 DNAH5	5.47e-03	28	79	2	GO:0051959
GeneOntologyMolecularFunction	dioxygenase activity	TET2 PLOD2 TET3	6.92e-03	98	79	3	GO:0051213
GeneOntologyBiologicalProcess	telomerase holoenzyme complex assembly	ATM HSP90AA1 HSP90AB1	9.54e-07	6	76	3	GO:1905323
GeneOntologyBiologicalProcess	protein folding	UBE4B SACS PEX19 HSP90AB2P HSP90AA1 TBCE HSP90AB1 HSP90AB3P	3.42e-06	246	76	8	GO:0006457
GeneOntologyBiologicalProcess	response to heat	GCLC HSP90AB2P ATM HSP90AA1 HSP90AB1 HSP90AB3P	5.63e-06	121	76	6	GO:0009408
GeneOntologyBiologicalProcess	protein ubiquitination	UBR2 UBE4B UBE3A GCLC RPS2 ASB4 HERC3 UBE3C ANAPC5 HERC4 HSP90AA1 FBXW7 HSP90AB1	7.53e-06	811	76	13	GO:0016567
GeneOntologyBiologicalProcess	cellular response to heat	HSP90AB2P ATM HSP90AA1 HSP90AB1 HSP90AB3P	1.22e-05	81	76	5	GO:0034605
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	UBR2 USP8 UBE4B UBE3A GCLC RPS2 ASB4 HERC3 UBE3C ANAPC5 HERC4 HSP90AA1 FBXW7 HSP90AB1	1.65e-05	1009	76	14	GO:0070647
GeneOntologyBiologicalProcess	protein modification by small protein conjugation	UBR2 UBE4B UBE3A GCLC RPS2 ASB4 HERC3 UBE3C ANAPC5 HERC4 HSP90AA1 FBXW7 HSP90AB1	2.09e-05	893	76	13	GO:0032446
GeneOntologyBiologicalProcess	autophagy of peroxisome	PIK3R4 PIK3C3 ATM	2.60e-05	16	76	3	GO:0030242
GeneOntologyBiologicalProcess	post-translational protein modification	UBR2 USP8 UBE4B UBE3A GCLC RPS2 ASB4 HERC3 UBE3C ANAPC5 HERC4 HSP90AA1 FBXW7 HSP90AB1	3.30e-05	1074	76	14	GO:0043687
GeneOntologyBiologicalProcess	protein catabolic process	UBR2 USP8 UBE4B UBE3A GCLC OAZ2 HERC3 ATM UBE3C ANAPC5 HERC4 HSP90AA1 FBXW7 HSP90AB1	4.97e-05	1115	76	14	GO:0030163
GeneOntologyBiologicalProcess	phosphatidylinositol-3-phosphate biosynthetic process	PIK3R4 PIK3C3 ATM	7.04e-05	22	76	3	GO:0036092
GeneOntologyBiologicalProcess	ubiquitin-dependent protein catabolic process	UBR2 UBE4B UBE3A GCLC HERC3 UBE3C ANAPC5 HERC4 FBXW7 HSP90AB1	1.16e-04	640	76	10	GO:0006511
GeneOntologyBiologicalProcess	response to temperature stimulus	GCLC HSP90AB2P ATM HSP90AA1 HSP90AB1 HSP90AB3P	1.19e-04	208	76	6	GO:0009266
GeneOntologyBiologicalProcess	modification-dependent protein catabolic process	UBR2 UBE4B UBE3A GCLC HERC3 UBE3C ANAPC5 HERC4 FBXW7 HSP90AB1	1.34e-04	651	76	10	GO:0019941
GeneOntologyBiologicalProcess	modification-dependent macromolecule catabolic process	UBR2 UBE4B UBE3A GCLC HERC3 UBE3C ANAPC5 HERC4 FBXW7 HSP90AB1	1.42e-04	656	76	10	GO:0043632
GeneOntologyBiologicalProcess	negative regulation of TOR signaling	UBR2 UBE3A DEPDC5 ATM	1.61e-04	74	76	4	GO:0032007
GeneOntologyBiologicalProcess	regulation of protein ubiquitination	UBE3A GCLC RPS2 HSP90AA1 FBXW7 HSP90AB1	1.87e-04	226	76	6	GO:0031396
GeneOntologyBiologicalProcess	protein stabilization	PEX19 HSP90AB2P HSP90AA1 FBXW7 HSP90AB1 HSP90AB3P	2.76e-04	243	76	6	GO:0050821
GeneOntologyBiologicalProcess	regulation of protein stability	USP8 PEX19 HSP90AB2P HSP90AA1 FBXW7 HSP90AB1 HSP90AB3P	4.13e-04	368	76	7	GO:0031647
GeneOntologyBiologicalProcess	protein maturation	UBE4B SACS PIK3C3 PEX19 HSP90AB2P HSP90AA1 TBCE HSP90AB1 HSP90AB3P	4.43e-04	619	76	9	GO:0051604
GeneOntologyBiologicalProcess	response to nitrosative stress	GCLC ATM	4.74e-04	9	76	2	GO:0051409
GeneOntologyBiologicalProcess	regulation of protein modification by small protein conjugation or removal	UBE3A GCLC RPS2 HSP90AA1 FBXW7 HSP90AB1	4.93e-04	271	76	6	GO:1903320
GeneOntologyCellularComponent	intracellular protein-containing complex	DOCK1 RNASEH2B UBR2 ERCC2 WASHC4 UBE4B UBE3A EIF4G2 DEPDC5 ASB4 UBE3C ANAPC5 PCGF5 FBXW7 HSP90AB1	2.58e-06	972	78	15	GO:0140535
GeneOntologyCellularComponent	phosphatidylinositol 3-kinase complex, class III, type II	PIK3R4 PIK3C3	8.21e-05	4	78	2	GO:0034272
GeneOntologyCellularComponent	phosphatidylinositol 3-kinase complex, class III, type I	PIK3R4 PIK3C3	8.21e-05	4	78	2	GO:0034271
GeneOntologyCellularComponent	phosphatidylinositol 3-kinase complex, class III	PIK3R4 PIK3C3	2.85e-04	7	78	2	GO:0035032
GeneOntologyCellularComponent	ubiquitin ligase complex	UBR2 UBE4B DEPDC5 ASB4 ANAPC5 PCGF5 FBXW7	3.43e-04	352	78	7	GO:0000151
GeneOntologyCellularComponent	dendritic growth cone	HSP90AA1 HSP90AB1	8.85e-04	12	78	2	GO:0044294
Domain	HECT	UBE3A HERC3 UBE3C HERC4	3.72e-06	27	74	4	PF00632
Domain	HECTc	UBE3A HERC3 UBE3C HERC4	3.72e-06	27	74	4	SM00119
Domain	HECT_dom	UBE3A HERC3 UBE3C HERC4	3.72e-06	27	74	4	IPR000569
Domain	HECT	UBE3A HERC3 UBE3C HERC4	3.72e-06	27	74	4	PS50237
Domain	Heat_shock_protein_90_CS	HSP90AA1 HSP90AB1	4.63e-05	3	74	2	IPR019805
Domain	-	SACS HSP90AA1 HSP90AB1	6.48e-05	20	74	3	3.30.565.10
Domain	HATPase_C	SACS HSP90AA1 HSP90AB1	7.54e-05	21	74	3	IPR003594
Domain	Hsp90_fam	HSP90AA1 HSP90AB1	9.24e-05	4	74	2	IPR001404
Domain	Hsp90_N	HSP90AA1 HSP90AB1	9.24e-05	4	74	2	IPR020575
Domain	HSP90	HSP90AA1 HSP90AB1	9.24e-05	4	74	2	PF00183
Domain	HSP90	HSP90AA1 HSP90AB1	9.24e-05	4	74	2	PS00298
Domain	Ribosomal_S5_D2-typ_fold	RPS2 HSP90AA1 HSP90AB1	3.27e-04	34	74	3	IPR020568
Domain	ARM-type_fold	PIK3R4 DOCK1 SAAL1 DOCK11 PIK3C3 EIF4G2 ATM	3.87e-04	339	74	7	IPR016024
Domain	CAP_GLY	CEP350 TBCE	6.83e-04	10	74	2	PF01302
Domain	CAP_GLY_1	CEP350 TBCE	6.83e-04	10	74	2	PS00845
Domain	CAP_GLY_2	CEP350 TBCE	6.83e-04	10	74	2	PS50245
Domain	CAP-Gly_domain	CEP350 TBCE	6.83e-04	10	74	2	IPR000938
Domain	CAP_GLY	CEP350 TBCE	6.83e-04	10	74	2	SM01052
Domain	-	CEP350 TBCE	6.83e-04	10	74	2	2.30.30.190
Domain	DOCK_C	DOCK1 DOCK11	8.32e-04	11	74	2	IPR010703
Domain	DHR-1_domain	DOCK1 DOCK11	8.32e-04	11	74	2	IPR027007
Domain	DHR_2	DOCK1 DOCK11	8.32e-04	11	74	2	PS51651
Domain	DHR_1	DOCK1 DOCK11	8.32e-04	11	74	2	PS51650
Domain	DOCK-C2	DOCK1 DOCK11	8.32e-04	11	74	2	PF14429
Domain	DHR-2	DOCK1 DOCK11	8.32e-04	11	74	2	IPR027357
Domain	DHR-2	DOCK1 DOCK11	8.32e-04	11	74	2	PF06920
Domain	DOCK	DOCK1 DOCK11	8.32e-04	11	74	2	IPR026791
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH5	1.37e-03	14	74	2	IPR024317
Domain	Dynein_HC_stalk	DNAH3 DNAH5	1.37e-03	14	74	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH3 DNAH5	1.37e-03	14	74	2	IPR013602
Domain	DHC_N2	DNAH3 DNAH5	1.37e-03	14	74	2	PF08393
Domain	MT	DNAH3 DNAH5	1.37e-03	14	74	2	PF12777
Domain	AAA_8	DNAH3 DNAH5	1.37e-03	14	74	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH3 DNAH5	1.37e-03	14	74	2	IPR011704
Domain	AAA_5	DNAH3 DNAH5	1.37e-03	14	74	2	PF07728
Domain	DHC_fam	DNAH3 DNAH5	1.57e-03	15	74	2	IPR026983
Domain	Dynein_heavy_dom	DNAH3 DNAH5	1.57e-03	15	74	2	IPR004273
Domain	Dynein_heavy	DNAH3 DNAH5	1.57e-03	15	74	2	PF03028
Domain	PI3/4_kinase_CS	PIK3C3 ATM	1.57e-03	15	74	2	IPR018936
Domain	-	PIK3C3 ATM	1.79e-03	16	74	2	1.10.1070.11
Domain	PI3Kc	PIK3C3 ATM	1.79e-03	16	74	2	SM00146
Domain	PI3/4_kinase_cat_dom	PIK3C3 ATM	2.27e-03	18	74	2	IPR000403
Domain	PI3_PI4_kinase	PIK3C3 ATM	2.27e-03	18	74	2	PF00454
Domain	PI3_4_KINASE_3	PIK3C3 ATM	2.27e-03	18	74	2	PS50290
Domain	PI3_4_KINASE_1	PIK3C3 ATM	2.27e-03	18	74	2	PS00915
Domain	PI3_4_KINASE_2	PIK3C3 ATM	2.27e-03	18	74	2	PS00916
Domain	HATPase_c	HSP90AA1 HSP90AB1	2.27e-03	18	74	2	SM00387
Domain	HATPase_c	HSP90AA1 HSP90AB1	2.54e-03	19	74	2	PF02518
Domain	AAA+_ATPase	DNAH3 DNAH5 SNRNP200 ABCA10	2.57e-03	144	74	4	IPR003593
Domain	AAA	DNAH3 DNAH5 SNRNP200 ABCA10	2.57e-03	144	74	4	SM00382
Domain	RCC1	HERC3 HERC4	2.81e-03	20	74	2	PF00415
Domain	RCC1_1	HERC3 HERC4	3.10e-03	21	74	2	PS00625
Domain	RCC1_2	HERC3 HERC4	3.10e-03	21	74	2	PS00626
Domain	RCC1_3	HERC3 HERC4	3.10e-03	21	74	2	PS50012
Domain	Reg_chr_condens	HERC3 HERC4	3.40e-03	22	74	2	IPR000408
Domain	-	HERC3 HERC4	3.40e-03	22	74	2	2.130.10.30
Domain	RCC1/BLIP-II	HERC3 HERC4	3.71e-03	23	74	2	IPR009091
Pathway	KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS	UBE4B UBE3A HERC3 UBE3C ANAPC5 HERC4 FBXW7	1.42e-06	135	59	7	M15247
Pathway	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	PIK3R4 UBR2 PIK3C3 UBE3A ASB4 HERC3 UBE3C ANAPC5 HERC4 FBXW7	3.56e-06	381	59	10	M1066
Pathway	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	UBR2 UBE3A ASB4 HERC3 UBE3C ANAPC5 HERC4 FBXW7	3.23e-05	299	59	8	MM15711
Pathway	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	UBR2 UBE3A ASB4 HERC3 UBE3C ANAPC5 HERC4 FBXW7	3.99e-05	308	59	8	M1070
Pathway	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	UBR2 UBE3A ASB4 HERC3 UBE3C ANAPC5 HERC4 FBXW7	8.51e-05	343	59	8	MM15712
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATXN3_TO_AUTOPHAGY_VESICLE_NUCLEATION	PIK3R4 PIK3C3	2.56e-04	6	59	2	M47662
Pathway	REACTOME_UPTAKE_AND_FUNCTION_OF_DIPHTHERIA_TOXIN	HSP90AA1 HSP90AB1	2.56e-04	6	59	2	M27430
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_AUTOPHAGY_VESICLE_NUCLEATION	PIK3R4 PIK3C3	2.56e-04	6	59	2	M47681
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	PIK3R4 DOCK1 PTPN13 DLC1 ARHGEF10 DOCK11 PIK3C3 CDC42BPB HSP90AA1 HSP90AB1	3.25e-04	649	59	10	MM15690
Pathway	KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_PACER_RUBCN_PI3KC3_C2	PIK3R4 PIK3C3	3.57e-04	7	59	2	M47976
Pathway	KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_E3_UBIQUITIN_LIGASE_MALIN	PIK3R4 PIK3C3	3.57e-04	7	59	2	M47977
Pathway	REACTOME_RHO_GTPASE_CYCLE	DOCK1 PTPN13 DLC1 ARHGEF10 DOCK11 CDC42BPB HSP90AA1 HSP90AB1	4.57e-04	439	59	8	MM15595
Pathway	REACTOME_HSF1_ACTIVATION	HSP90AA1 HSP90AB1	4.74e-04	8	59	2	MM14950
Pathway	KEGG_MEDICUS_REFERENCE_EARLY_ENDOSOMAL_FUSION	PIK3R4 PIK3C3	4.74e-04	8	59	2	M47778
Pathway	REACTOME_AUTOPHAGY	PIK3R4 PIK3C3 ATM HSP90AA1 HSP90AB1	5.10e-04	158	59	5	M27935
Pathway	REACTOME_RHO_GTPASE_CYCLE	DOCK1 PTPN13 DLC1 ARHGEF10 DOCK11 CDC42BPB HSP90AA1 HSP90AB1	5.38e-04	450	59	8	M27078
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	PIK3R4 DOCK1 PTPN13 DLC1 ARHGEF10 DOCK11 PIK3C3 CDC42BPB HSP90AA1 HSP90AB1	7.34e-04	720	59	10	M41838
Pathway	REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE	PIK3R4 PIK3C3	7.58e-04	10	59	2	MM14644
Pathway	KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_PI3P_SYNTHESIS_BY_PI3KC3_C1	PIK3R4 PIK3C3	7.58e-04	10	59	2	M47974
Pathway	REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE	PIK3R4 PIK3C3	9.24e-04	11	59	2	M655
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CEP350 PIK3R4 TET2 USP8 PTPN13 WASHC4 UBE4B SACS ARHGEF10 UBE3A EIF4G2 NAP1L3 ATM CDC42BPB SNRNP200 SNTA1 HSP90AA1 HSP90AB1	4.76e-10	1285	79	18	35914814
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	RNASEH2B USP8 WASHC4 UBE4B ARHGEF10 UBE3A GCLC RPS2 NIF3L1 SAMHD1 HSP90AB2P UBE3C PLOD2 HERC4 SNRNP200 HSP90AA1 TBCE HSP90AB1	3.38e-09	1455	79	18	22863883
Pubmed	The HSP90 family of genes in the human genome: insights into their divergence and evolution.	HSP90AB2P HSP90AA1 HSP90AB1 HSP90AB3P	4.39e-08	16	79	4	16269234
Pubmed	Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.	DOCK1 GPD2 UBE4B UBE3A UBE3C GTPBP10 HERC4	2.10e-07	183	79	7	31932471
Pubmed	Characterization of human hect domain family members and their interaction with UbcH5 and UbcH7.	UBE3A HERC3 UBE3C	9.38e-07	9	79	3	9575161
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	SAAL1 WASHC4 RPS2 EIF4G2 ASB4 HSP90AB2P KCTD1 PLOD2 ANAPC5 SNRNP200 PCGF5 HSP90AA1 HSP90AB1 HSP90AB3P	1.70e-06	1335	79	14	29229926
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	UBR2 UBE3A HERC3 UBE3C HERC4	2.63e-06	95	79	5	29643511
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CEP350 PIK3R4 TET2 FSIP2 USP8 PTPN13 DLC1 ARHGEF10 DOCK11 PIK3C3 STIL	3.92e-06	861	79	11	36931259
Pubmed	HSP90 is necessary for the ACK1-dependent phosphorylation of STAT1 and STAT3.	HSP90AB2P HSP90AA1 HSP90AB1	4.03e-06	14	79	3	28739485
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	GPD2 SAAL1 EIF4G2 PEX19 SAMHD1 HSP90AB2P ATM UBE3C TMX3 PLOD2 GTPBP10 SNRNP200 HSP90AA1 SLC27A2	4.09e-06	1440	79	14	30833792
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	CEP350 GPD2 UBR2 CNNM1 PTPN13 SAAL1 SMG7 PEX19 CDC42BPB HSP90AA1 FBXW7 HSP90AB1	4.25e-06	1049	79	12	27880917
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	DOCK1 GPD2 PTPN13 RPS2 EIF4G2 LRRC40 SNRNP200 HSP90AA1 TBCE HSP90AB1	4.67e-06	708	79	10	39231216
Pubmed	Expression of hsp90 and cyclin D1 in human breast cancer.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	10376793
Pubmed	Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	33179566
Pubmed	Regulation of embryonic stem cell pluripotency by heat shock protein 90.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	22696450
Pubmed	Acute loss of TET function results in aggressive myeloid cancer in mice.	TET2 TET3	5.09e-06	2	79	2	26607761
Pubmed	Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	22895790
Pubmed	Epigenetic silencing of TET2 and TET3 induces an EMT-like process in melanoma.	TET2 TET3	5.09e-06	2	79	2	27852070
Pubmed	Hsp90 is cleaved by reactive oxygen species at a highly conserved N-terminal amino acid motif.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	22848402
Pubmed	Expression of Hsp90 chaperone [corrected] proteins in human tumor tissue.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	19576239
Pubmed	A mouse tumor-specific transplantation antigen is a heat shock-related protein.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	3458168
Pubmed	Mechanism of dimer formation of the 90-kDa heat-shock protein.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	7588731
Pubmed	TET proteins regulate Drosha expression and impact microRNAs in iNKT cells.	TET2 TET3	5.09e-06	2	79	2	39364402
Pubmed	hVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cells.	PIK3R4 PIK3C3	5.09e-06	2	79	2	18957027
Pubmed	ATM is the primary kinase responsible for phosphorylation of Hsp90α after ionizing radiation.	ATM HSP90AA1	5.09e-06	2	79	2	27738310
Pubmed	High expression of PI3K core complex genes is associated with poor prognosis in chronic lymphocytic leukemia.	PIK3R4 PIK3C3	5.09e-06	2	79	2	25840748
Pubmed	Murine 86- and 84-kDa heat shock proteins, cDNA sequences, chromosome assignments, and evolutionary origins.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	2925609
Pubmed	Some mutations in the xeroderma pigmentosum D gene may lead to moderate but significant radiosensitivity associated with a delayed radiation-induced ATM nuclear localization.	ERCC2 ATM	5.09e-06	2	79	2	31738647
Pubmed	Ten-eleven translocation (Tet) methylcytosine dioxygenase-dependent viral DNA demethylation mediates in vivo hepatitis B virus (HBV) biosynthesis.	TET2 TET3	5.09e-06	2	79	2	38179947
Pubmed	Heat-shock proteins, Hsp84 and Hsp86, of mice and men: two related genes encode formerly identified tumour-specific transplantation antigens.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	2469626
Pubmed	TET2 and TET3 loss disrupts small intestine differentiation and homeostasis.	TET2 TET3	5.09e-06	2	79	2	37414790
Pubmed	TET enzymes control antibody production and shape the mutational landscape in germinal centre B cells.	TET2 TET3	5.09e-06	2	79	2	31120187
Pubmed	HSP90 expression and early recurrence in gastroenteropancreatic neuroendocrine tumors: Potential for a novel therapeutic target.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	33080545
Pubmed	Heat shock protein 90 facilitates SARS-CoV-2 structural protein-mediated virion assembly and promotes virus-induced pyroptosis.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	37011862
Pubmed	Role of Chromatin Remodeling Genes and TETs in the Development of Human Midbrain Dopaminergic Neurons.	TET2 TET3	5.09e-06	2	79	2	32367481
Pubmed	Translational reprogramming in response to accumulating stressors ensures critical threshold levels of Hsp90 for mammalian life.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	36270993
Pubmed	Hsp90 regulation of fibroblast activation in pulmonary fibrosis.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	28239659
Pubmed	Molecular pathogenesis of progression to myeloid leukemia from TET-insufficient status.	TET2 TET3	5.09e-06	2	79	2	32126143
Pubmed	Distinct roles for TET family proteins in regulating human erythropoiesis.	TET2 TET3	5.09e-06	2	79	2	28167661
Pubmed	Despite their structural similarities, the cytosolic isoforms of human Hsp90 show different behaviour in thermal unfolding due to their conformation: An FTIR study.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	37028636
Pubmed	Proliferation, migration, and resistance to oxidative and thermal stresses of HT1080 cells with knocked out genes encoding Hsp90α and Hsp90β.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	37406487
Pubmed	Expression and therapeutic relevance of heat-shock protein 90 in pancreatic endocrine tumors.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	22194440
Pubmed	Circadian expression of 86- and 84-kDa heat shock proteins in the mouse suprachiasmatic nucleus.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	18480550
Pubmed	Retinol and ascorbate drive erasure of epigenetic memory and enhance reprogramming to naïve pluripotency by complementary mechanisms.	TET2 TET3	5.09e-06	2	79	2	27729528
Pubmed	Mitochondrial heat shock protein-90 modulates vascular smooth muscle cell survival and the vascular injury response in vivo.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	22841823
Pubmed	Substitution of only two residues of human Hsp90alpha causes impeded dimerization of Hsp90beta.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	18347946
Pubmed	Heat shock protein 90 overexpression independently predicts inferior disease-free survival with differential expression of the alpha and beta isoforms in gastrointestinal stromal tumors.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	19047110
Pubmed	Conserved conformational changes in the ATPase cycle of human Hsp90.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	18400751
Pubmed	Inhibition of RPE cell sterile inflammatory responses and endotoxin-induced uveitis by a cell-impermeable HSP90 inhibitor.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	22019372
Pubmed	Heat shock protein HSP86 expression during mouse embryo development, especially in the germ-line.	HSP90AA1 HSP90AB1	5.09e-06	2	79	2	12136260
Pubmed	A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.	UBE3A UBE3C HERC4	6.18e-06	16	79	3	22496338
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	CEP350 PTPN13 SAAL1 WASHC4 UBE3A PEX19 UBE3C PLOD2 MTARC1 SLC27A2	8.09e-06	754	79	10	33060197
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	SAAL1 UBE4B UBE3A MTX3 EIF4G2 LRRC40 SAMHD1 TMX3 PLOD2 ANAPC5 HSP90AB1	9.15e-06	942	79	11	31073040
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	PIK3R4 UBR2 PIK3C3 UBE3A GCLC UBE3C	9.17e-06	212	79	6	33853758
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	SACS ARHGEF10 PEX19 DNAH5 CDC42BPB HSP90AA1 HSP90AB1	1.09e-05	332	79	7	37433992
Pubmed	Hypermethylation of UCHL1 Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN).	USP8 CCDC66 HSP90AA1 HSP90AB1	1.50e-05	65	79	4	32120844
Pubmed	Expression of TET and 5-HmC in Trophoblast Villi of Women with Normal Pregnancy and with Early Pregnancy Loss.	TET2 TET3	1.53e-05	3	79	2	30074219
Pubmed	Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter.	TET2 TET3	1.53e-05	3	79	2	24194590
Pubmed	TET proteins in malignant hematopoiesis.	TET2 TET3	1.53e-05	3	79	2	19923888
Pubmed	Molecular recognition via coupled folding and binding in a TPR domain.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	15713458
Pubmed	Selective targeting of TET catalytic domain promotes somatic cell reprogramming.	TET2 TET3	1.53e-05	3	79	2	32024762
Pubmed	Tet Enzymes Regulate Telomere Maintenance and Chromosomal Stability of Mouse ESCs.	TET2 TET3	1.53e-05	3	79	2	27184841
Pubmed	Two human 90-kDa heat shock proteins are phosphorylated in vivo at conserved serines that are phosphorylated in vitro by casein kinase II.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	2492519
Pubmed	Conformational activation of a basic helix-loop-helix protein (MyoD1) by the C-terminal region of murine HSP90 (HSP84).	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	1406681
Pubmed	Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.	TET2 TET3	1.53e-05	3	79	2	21778364
Pubmed	Tet family proteins and 5-hydroxymethylcytosine in development and disease.	TET2 TET3	1.53e-05	3	79	2	22569552
Pubmed	Mammalian CHORD-containing protein 1 is a novel heat shock protein 90-interacting protein.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	15642353
Pubmed	Mutations that increase both Hsp90 ATPase activity in vitro and Hsp90 drug resistance in vivo.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	20226818
Pubmed	Signal transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9.	PIK3R4 PIK3C3	1.53e-05	3	79	2	14751759
Pubmed	Postnatal DNA demethylation and its role in tissue maturation.	TET2 TET3	1.53e-05	3	79	2	29795194
Pubmed	Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.	TET2 TET3	1.53e-05	3	79	2	19372391
Pubmed	Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs.	TET2 TET3	1.53e-05	3	79	2	30987683
Pubmed	Does single gene expression omnibus data mining analysis apply for only tumors and not mental illness? A preliminary study on bipolar disorder based on bioinformatics methodology.	UBE3A HSP90AA1	1.53e-05	3	79	2	32871949
Pubmed	Improvement of Foxp3 stability through CNS2 demethylation by TET enzyme induction and activation.	TET2 TET3	1.53e-05	3	79	2	29048538
Pubmed	Modulation of Akt kinase activity by binding to Hsp90.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	10995457
Pubmed	Regulation of cytosolic phospholipase A2alpha by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	18550790
Pubmed	N-terminal domain of human Hsp90 triggers binding to the cochaperone p23.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	21183720
Pubmed	Synergistic role of HSP90α and HSP90β to promote myofibroblast persistence in lung fibrosis.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	29386344
Pubmed	Hsp90 stabilizes Cdc25A and counteracts heat shock-mediated Cdc25A degradation and cell-cycle attenuation in pancreatic carcinoma cells.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	22843495
Pubmed	HSP90 affects the stability of BMAL1 and circadian gene expression.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	24682203
Pubmed	Mechanisms of TET protein-mediated DNA demethylation and its role in the regulation of mouse development.	TET2 TET3	1.53e-05	3	79	2	25608811
Pubmed	Mammalian heat shock factor 1 is essential for oocyte meiosis and directly regulates Hsp90alpha expression.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	19158073
Pubmed	Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies.	TET2 TET3	1.53e-05	3	79	2	19420352
Pubmed	Overexpression of TET dioxygenases in seminomas associates with low levels of DNA methylation and hydroxymethylation.	TET2 TET3	1.53e-05	3	79	2	28218476
Pubmed	Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	22849407
Pubmed	Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine.	TET2 TET3	1.53e-05	3	79	2	23548903
Pubmed	Conformational diversity in the TPR domain-mediated interaction of protein phosphatase 5 with Hsp90.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	16531226
Pubmed	5-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and function.	TET2 TET3	1.53e-05	3	79	2	34919053
Pubmed	Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells.	TET2 TET3	1.53e-05	3	79	2	24958354
Pubmed	Heat Shock Protein 90 Family Isoforms as Prognostic Biomarkers and Their Correlations with Immune Infiltration in Breast Cancer.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	33145341
Pubmed	Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	19996089
Pubmed	HSP-enriched properties of extracellular vesicles involve survival of metastatic oral cancer cells.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	29768689
Pubmed	One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering.	TET2 TET3	1.53e-05	3	79	2	23643243
Pubmed	Monogenic and polygenic determinants of sarcoma risk: an international genetic study.	ERCC2 ATM	1.53e-05	3	79	2	27498913
Pubmed	Tissue-specific DNA demethylation is required for proper B-cell differentiation and function.	TET2 TET3	1.53e-05	3	79	2	27091986
Pubmed	Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation.	TET2 TET3	1.53e-05	3	79	2	34879277
Pubmed	Hsp90 activity is necessary to acquire a proper neuronal polarization.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	24286867
Pubmed	Oxygen regulation of TET enzymes.	TET2 TET3	1.53e-05	3	79	2	33410283
Pubmed	Hsp90 regulates the activity of wild type p53 under physiological and elevated temperatures.	HSP90AA1 HSP90AB1	1.53e-05	3	79	2	15358771
Pubmed	Effect of aging on 5-hydroxymethylcytosine in brain mitochondria.	TET2 TET3	1.53e-05	3	79	2	22445327
Interaction	SPSB4 interactions	PIK3R4 DOCK1 SACS ARHGEF10 PIK3C3 MTX3 LRRC40	5.18e-07	124	78	7	int:SPSB4
Interaction	ZNF215 interactions	LRRC40 HERC4 HSP90AA1 HSP90AB1	1.44e-06	22	78	4	int:ZNF215
Interaction	PTEN interactions	FSIP2 USP8 PTPN13 CASD1 DLC1 GCLC RPS2 CAPRIN2 ATM FSBP ANAPC5 SNRNP200 HSP90AA1 FBXW7 HSP90AB1	2.31e-06	929	78	15	int:PTEN
Interaction	SLC17A1 interactions	HSP90AA1 FBXW7 HSP90AB1	3.08e-06	8	78	3	int:SLC17A1
Interaction	CUL4A interactions	DLC1 WASHC4 UBE3A GCLC RPS2 DEPDC5 ASB4 SAMHD1 ANAPC5 SNRNP200 ABCA10 HSP90AA1 SLC27A2 HSP90AB1	4.44e-06	854	78	14	int:CUL4A
Interaction	CDKL4 interactions	HSP90AA1 HSP90AB1 HSP90AB3P	1.55e-05	13	78	3	int:CDKL4
Interaction	HERC6 interactions	HERC3 HERC4 HSP90AA1	1.97e-05	14	78	3	int:HERC6
Interaction	EGLN1 interactions	TET2 PEX19 TET3 HSP90AA1 HSP90AB1	2.74e-05	91	78	5	int:EGLN1
Interaction	RPS6KA1 interactions	DLC1 WASHC4 HSP90AB2P ATM SNTA1 HSP90AA1 HSP90AB1	2.89e-05	228	78	7	int:RPS6KA1
Interaction	DUSP16 interactions	CEP350 SMG7 UBE4B STIL ANAPC5 SNRNP200 FBXW7	3.70e-05	237	78	7	int:DUSP16
Interaction	STYK1 interactions	PIK3R4 PTPN13 ARHGEF10 PIK3C3 HSP90AA1 HSP90AB1	3.78e-05	161	78	6	int:STYK1
Interaction	SLC34A1 interactions	PEX19 HSP90AA1 HSP90AB1	5.17e-05	19	78	3	int:SLC34A1
Interaction	CRYL1 interactions	SMG7 STIL ANAPC5 HSP90AB1	6.55e-05	56	78	4	int:CRYL1
Interaction	CDK11A interactions	SMG7 PCGF5 HSP90AA1 FBXW7 HSP90AB1 HSP90AB3P	7.04e-05	180	78	6	int:CDK11A
Interaction	UNC45B interactions	HSP90AA1 HSP90AB1 HSP90AB3P	8.15e-05	22	78	3	int:UNC45B
Interaction	PGK1 interactions	PIK3C3 UBE3A RPS2 EIF4G2 DNAH5 PCGF5 HSP90AA1 HSP90AB1	8.66e-05	367	78	8	int:PGK1
Interaction	CUL2 interactions	TET2 DLC1 RPS2 ASB4 SAMHD1 HSP90AB2P PLOD2 SNRNP200 HSP90AA1 HSP90AB1	9.13e-05	591	78	10	int:CUL2
Interaction	TET3 interactions	TET2 TET3 HSP90AB1	9.34e-05	23	78	3	int:TET3
Interaction	GUCY2D interactions	CNGA3 HSP90AA1 HSP90AB3P	9.34e-05	23	78	3	int:GUCY2D
Interaction	CRY2 interactions	RPS2 SNRNP200 HSP90AA1 FBXW7 HSP90AB1 HSP90AB3P	1.06e-04	194	78	6	int:CRY2
Interaction	STIP1 interactions	PIK3R4 ARHGEF10 RPS2 EIF4G2 LRRC40 SAMHD1 HSP90AB2P UBE3C STIL SNRNP200 HSP90AA1 HSP90AB1 HSP90AB3P	1.19e-04	1006	78	13	int:STIP1
Interaction	NHLRC1 interactions	PIK3R4 PIK3C3 HSP90AA1	1.21e-04	25	78	3	int:NHLRC1
Interaction	GRK7 interactions	HSP90AA1 HSP90AB1 HSP90AB3P	1.21e-04	25	78	3	int:GRK7
Interaction	ITGB1BP2 interactions	PLOD2 HSP90AA1 HSP90AB1	1.21e-04	25	78	3	int:ITGB1BP2
Interaction	KCNA3 interactions	DOCK1 GPD2 PTPN13 RPS2 CAPRIN2 EIF4G2 LRRC40 DNAH5 SNRNP200 HSP90AA1 TBCE HSP90AB1	1.24e-04	871	78	12	int:KCNA3
Interaction	IRAK2 interactions	SAMHD1 PLOD2 SNRNP200 HSP90AA1	1.25e-04	66	78	4	int:IRAK2
Interaction	DDX59 interactions	HSP90AA1 FBXW7 HSP90AB1	1.36e-04	26	78	3	int:DDX59
Interaction	METTL22 interactions	HSP90AB2P HSP90AA1 HSP90AB1	1.36e-04	26	78	3	int:METTL22
Interaction	CCDC117 interactions	HSP90AA1 HSP90AB1 HSP90AB3P	1.36e-04	26	78	3	int:CCDC117
Interaction	SUGT1 interactions	ARHGEF10 UBE3A LRRC40 SAMHD1 STIL HSP90AA1 HSP90AB1	1.40e-04	293	78	7	int:SUGT1
Interaction	AWAT2 interactions	UBE3A HERC3	1.47e-04	5	78	2	int:AWAT2
Interaction	COPS6 interactions	UBE3A RPS2 CAPRIN2 SAMHD1 SNRNP200 HSP90AA1 FBXW7 HSP90AB1	1.79e-04	408	78	8	int:COPS6
Interaction	CD33 interactions	SAAL1 PEX19 HERC3	1.90e-04	29	78	3	int:CD33
Interaction	STK35 interactions	HSP90AA1 HSP90AB1 HSP90AB3P	2.10e-04	30	78	3	int:STK35
Interaction	PRKY interactions	PTPN13 SMG7 HERC4 HSP90AA1 TBCE	2.12e-04	140	78	5	int:PRKY
Interaction	SPDL1 interactions	DOCK1 RPS2 EIF4G2 SNRNP200 HSP90AA1 FBXW7 HSP90AB1	2.18e-04	315	78	7	int:SPDL1
Interaction	USP11 interactions	PIK3R4 PIK3C3 RPS2 SAMHD1 HSP90AB2P SNRNP200 HSP90AA1 HSP90AB1 HSP90AB3P	2.32e-04	539	78	9	int:USP11
Interaction	UNC45A interactions	UBE3A STIL HSP90AA1 SLC27A2 FBXW7 HSP90AB1	2.56e-04	228	78	6	int:UNC45A
Interaction	EIF4G1 interactions	CEP350 UBE3A RPS2 EIF4G2 SAMHD1 HSP90AA1 FBXW7 HSP90AB1	2.68e-04	433	78	8	int:EIF4G1
Interaction	YWHAG interactions	CEP350 PIK3R4 TET2 USP8 PTPN13 DLC1 DOCK11 PIK3C3 UBE3A RPS2 SNRNP200 HSP90AA1 FBXW7 HSP90AB1	2.78e-04	1248	78	14	int:YWHAG
Interaction	FAM32A interactions	HSP90AA1 FBXW7 HSP90AB1	2.80e-04	33	78	3	int:FAM32A
Interaction	IL24 interactions	UBE3A ATM FBXW7	2.80e-04	33	78	3	int:IL24
Interaction	RECQL4 interactions	UBR2 SAAL1 WASHC4 RPS2 EIF4G2 ASB4 HSP90AB2P KCTD1 PLOD2 ANAPC5 SNRNP200 PCGF5 HSP90AA1 HSP90AB1 HSP90AB3P	2.94e-04	1412	78	15	int:RECQL4
Interaction	EPHA1 interactions	PTPN13 SAAL1 RPS2 PEX19 UBE3C HSP90AA1	3.01e-04	235	78	6	int:EPHA1
Interaction	HIF1A interactions	CEP350 SAMHD1 ATM UBE3C SNRNP200 HSP90AA1 FBXW7 HSP90AB1	3.03e-04	441	78	8	int:HIF1A
Interaction	SBK2 interactions	HSP90AA1 HSP90AB1	3.07e-04	7	78	2	int:SBK2
Interaction	LETM2 interactions	HSP90AA1 FBXW7	3.07e-04	7	78	2	int:LETM2
Interaction	UBR4 interactions	DOCK11 RPS2 HERC4 SNRNP200 HSP90AA1 FBXW7 HSP90AB1	3.11e-04	334	78	7	int:UBR4
Interaction	PGR interactions	UBE3A HERC4 HSP90AA1 HSP90AB1	3.17e-04	84	78	4	int:PGR
Interaction	EPHB6 interactions	NIF3L1 MTARC1 HSP90AA1 HSP90AB1	3.17e-04	84	78	4	int:EPHB6
Interaction	USP19 interactions	SAAL1 PIK3C3 SNRNP200 HSP90AA1 HSP90AB1	3.29e-04	154	78	5	int:USP19
Interaction	XPA interactions	ERCC2 DLC1 ATM FBXW7	3.47e-04	86	78	4	int:XPA
Interaction	CAMKMT interactions	HSP90AB2P HSP90AA1 HSP90AB1	3.63e-04	36	78	3	int:CAMKMT
Interaction	HERC5 interactions	UBR2 ERCC2 UBE4B UBE3A RPS2 FBXW7	3.76e-04	245	78	6	int:HERC5
Interaction	HECTD1 interactions	PIK3R4 ARHGEF10 PIK3C3 RPS2 SAMHD1 KCTD1 UBE3C TTF1 GTPBP10 SNRNP200 FBXW7 HSP90AB1	3.80e-04	984	78	12	int:HECTD1
Interaction	CDC16 interactions	CEP350 SMG7 IZUMO1 STIL ANAPC5 FBXW7	3.84e-04	246	78	6	int:CDC16
Interaction	EGLN3 interactions	CEP350 PIK3R4 TET2 UBR2 PTPN13 SAAL1 SMG7 LRRC40 SAMHD1 HSP90AB2P STIL TMX3 ANAPC5 TET3	4.08e-04	1296	78	14	int:EGLN3
Interaction	NLRC3 interactions	HSP90AA1 HSP90AB1	4.08e-04	8	78	2	int:NLRC3
Interaction	FGR interactions	HSP90AB2P HSP90AA1 HSP90AB1 HSP90AB3P	4.67e-04	93	78	4	int:FGR
Interaction	FBXW11 interactions	DOCK1 PTPN13 SMG7 UBE4B SAMHD1 HERC3 STIL HSP90AA1	4.83e-04	473	78	8	int:FBXW11
Interaction	SRMS interactions	HSP90AA1 HSP90AB1 HSP90AB3P	4.97e-04	40	78	3	int:SRMS
Interaction	MAGEA1 interactions	UBE3A EIF4G2 NAP1L3 FBXW7	5.06e-04	95	78	4	int:MAGEA1
Interaction	EEF1AKMT3 interactions	WASHC4 ARHGEF10 UBE3A EIF4G2 HSP90AB2P HSP90AA1 HSP90AB1	5.21e-04	364	78	7	int:EEF1AKMT3
Interaction	ZNF541 interactions	HSP90AA1 HSP90AB1	5.23e-04	9	78	2	int:ZNF541
Interaction	FAM167A interactions	UBE3A ANAPC5 CDC42BPB FBXW7	5.27e-04	96	78	4	int:FAM167A
Interaction	PRKCE interactions	HSP90AB2P HSP90AA1 FBXW7 HSP90AB1 HSP90AB3P	5.60e-04	173	78	5	int:PRKCE
Interaction	RPS6KA4 interactions	WASHC4 HSP90AA1 HSP90AB1 HSP90AB3P	6.14e-04	100	78	4	int:RPS6KA4
Interaction	AURKC interactions	HSP90AA1 HSP90AB1 HSP90AB3P	6.16e-04	43	78	3	int:AURKC
Interaction	SGK2 interactions	HSP90AA1 HSP90AB1 HSP90AB3P	6.16e-04	43	78	3	int:SGK2
Interaction	SOCS1 interactions	HSP90AB2P ATM HSP90AA1 HSP90AB1 HSP90AB3P	6.21e-04	177	78	5	int:SOCS1
GeneFamily	Heat shock 90kDa proteins	HSP90AA1 HSP90AB1	6.03e-05	5	45	2	586
GeneFamily	Dyneins, axonemal	DNAH3 DNAH5	8.04e-04	17	45	2	536
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	CEP350 PIK3R4 DOCK1 TGFB2 UBR2 PTPN13 DLC1 WASHC4 SACS ARHGEF10 PIK3C3 UBE3A STIL PLOD2 HERC4	2.92e-08	856	78	15	M4500
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	CEP350 TET2 CNNM1 UBE4B DOCK11 DEPDC5 ATM STIL	6.59e-08	180	78	8	M8239
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	CEP350 USP8 PTPN13 SACS UBE3A CAPRIN2 NAP1L3 LRRC40 ATM HSP90AA1	2.45e-05	656	78	10	M18979
Coexpression	YAGI_AML_FAB_MARKERS	USP8 DLC1 NAP1L3 SAMHD1 PLOD2 SNTA1	2.51e-05	194	78	6	M5103
Coexpression	GSE17721_PAM3CSK4_VS_CPG_2H_BMDC_UP	CAPRIN2 SLC25A44 NIF3L1 UBE3C DNAH5 HSP90AA1	2.90e-05	199	78	6	M3857
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#3	PTPN13 WASHC4 SMG7 DOCK11 GCLC TMX3 HSP90AA1 HSP90AB1	9.01e-06	285	77	8	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K3
CoexpressionAtlas	facebase_RNAseq_e8.5_NeuroEpith_nonFloor_2500_K0	GPD2 RNASEH2B PTPN13 UBE3A CAPRIN2 NIF3L1 HERC3 ATM TMX3 TTF1 HSP90AA1 VCPKMT SLC27A2 HSP90AB3P	2.97e-05	1080	77	14	facebase_RNAseq_e8.5_NeuroEpith_nonFloor_2500_K0
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000	PTPN13 WASHC4 SMG7 DOCK11 UBE3A GCLC NIF3L1 ATM TMX3 CDC42BPB HSP90AA1 HSP90AB1 HSP90AB3P	5.27e-05	991	77	13	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000
CoexpressionAtlas	facebase_RNAseq_e8.5_NeuroEpith_nonFloor_2500	GPD2 RNASEH2B PTPN13 UBE3A CAPRIN2 NIF3L1 HERC3 ATM TMX3 TTF1 HSP90AA1 VCPKMT SLC27A2 HSP90AB3P	9.46e-05	1202	77	14	facebase_RNAseq_e8.5_NeuroEpith_nonFloor_2500
Drug	Phlorhizin	GPD2 UBR2 PIK3C3 GCLC ANAPC5 HSP90AA1 FBXW7 HSP90AB1	1.44e-06	235	78	8	ctd:D010695
Drug	Prostaglandin E1; Up 200; 10uM; PC3; HT_HG-U133A	TGFB2 SMG7 UBE4B ATM TTF1 HERC4 HSP90AB1	4.04e-06	190	78	7	6571_UP
Drug	5155877; Up 200; 10uM; MCF7; HT_HG-U133A	DOCK1 DNAH3 WASHC4 GCLC PEX19 HERC4 HSP90AB1	4.33e-06	192	78	7	6574_UP
Drug	PHA-00846566E [724718-26-7]; Up 200; 10uM; PC3; HT_HG-U133A	PIK3R4 ERCC2 ATM TTF1 ANAPC5 SNTA1 SLC27A2	4.64e-06	194	78	7	7086_UP
Drug	Methyldopa (L,-) [555-30-6]; Down 200; 19uM; HL60; HG-U133A	USP8 RPS2 PEX19 SLC25A44 SAMHD1 ANAPC5 VCPKMT	5.30e-06	198	78	7	1619_DN
Drug	Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Down 200; 16.4uM; MCF7; HT_HG-U133A	CASD1 UBE4B RPS2 ATM PLOD2 ANAPC5 HSP90AB1	5.30e-06	198	78	7	4810_DN
Drug	8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE	HSP90AA1 HSP90AB1	1.16e-05	2	78	2	DB07877
Drug	4-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOL	HSP90AA1 HSP90AB1	1.16e-05	2	78	2	DB07594
Drug	9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine	HSP90AA1 HSP90AB1	1.16e-05	2	78	2	DB02754
Drug	Geldanamycin	HSP90AA1 HSP90AB1	1.16e-05	2	78	2	DB02424
Drug	5-Methylcytosine	TET2 TET3	3.47e-05	3	78	2	ctd:D044503
Drug	Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; PC3; HT_HG-U133A	SMG7 SLC25A44 ATM ANAPC5 HERC4 SLC27A2	5.16e-05	192	78	6	4268_DN
Drug	Cephalexin monohydrate [23325-78-2]; Down 200; 11uM; HL60; HT_HG-U133A	SERPINB10 CASD1 RPS2 ATM ANAPC5 HERC4	5.16e-05	192	78	6	1273_DN
Drug	Glycocholic acid [475-31-0]; Down 200; 8.6uM; PC3; HT_HG-U133A	DOCK1 TGFB2 GPD2 UBE4B ATM ANAPC5	5.31e-05	193	78	6	6716_DN
Drug	Dacarbazine [4342-03-4]; Down 200; 22uM; HL60; HG-U133A	SERPINB10 WASHC4 RPS2 ATM PLOD2 TBCE	5.62e-05	195	78	6	1762_DN
Drug	Amprolium hydrochloride [137-88-2]; Down 200; 12.6uM; HL60; HG-U133A	SERPINB10 GPR18 RPS2 ANAPC5 VCPKMT HSP90AB1	5.62e-05	195	78	6	1979_DN
Drug	Fusidic acid sodium salt [751-94-0]; Down 200; 7.4uM; PC3; HT_HG-U133A	GPD2 SMG7 UBE4B ATM HERC4 FBXW7	5.62e-05	195	78	6	6754_DN
Drug	Cefmetazole sodium salt [56796-39-5]; Down 200; 8.2uM; PC3; HT_HG-U133A	GPD2 DNAH3 PIK3C3 PEX19 SLC25A44 SLC27A2	5.79e-05	196	78	6	5868_DN
Drug	Pimozide [2062-78-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A	TGFB2 PTPN13 ARHGEF10 UBE3A RPS2 HERC4	5.79e-05	196	78	6	6780_DN
Drug	Gly-His-Lys acetate salt; Up 200; 1uM; PC3; HT_HG-U133A	SMG7 UBE4B ATM HERC4 SLC27A2 HSP90AB1	5.79e-05	196	78	6	6570_UP
Drug	Dizocilpine maleate [77086-22-7]; Down 200; 11.8uM; HL60; HG-U133A	CEP350 WASHC4 RPS2 PEX19 LRRC40 UBE3C	5.95e-05	197	78	6	1386_DN
Drug	FK-506; Up 200; 1uM; MCF7; HG-U133A	ERCC2 SERPINB10 SMG7 UBE4B PEX19 CDC42BPB	5.95e-05	197	78	6	284_UP
Drug	Phthalylsulfathiazole [85-73-4]; Down 200; 10uM; HL60; HT_HG-U133A	SMG7 UBE4B PEX19 SLC25A44 DEPDC5 ANAPC5	6.12e-05	198	78	6	3033_DN
Drug	alpha-estradiol; Up 200; 0.01uM; MCF7; HG-U133A	DNAH3 GCLC RPS2 ATM CDC42BPB MTARC1	6.12e-05	198	78	6	762_UP
Drug	Cyclopentolate hydrochloride [5870-29-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A	UBR2 DNAH3 UBE4B ARHGEF10 ATM ANAPC5	6.29e-05	199	78	6	6214_DN
Drug	Lorglumide sodium salt [97964-56-2]; Down 200; 8.4uM; HL60; HT_HG-U133A	GPD2 SMG7 RPS2 DEPDC5 ANAPC5 HERC4	6.29e-05	199	78	6	3079_DN
Drug	N-(5-methylisoxazol-3-yl)-2-(4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-ylthio)acetamide	HSP90AA1 HSP90AB1	6.92e-05	4	78	2	ctd:C576667
Drug	Ax 2	RPS2 HSP90AA1 TBCE	7.43e-05	24	78	3	CID003086343
Drug	5-hydroxymethylcytosine	TET2 TET3	1.15e-04	5	78	2	ctd:C011865
Drug	1uyd	TET2 HSP90AA1	1.15e-04	5	78	2	CID000448970
Disease	cancer (implicated_via_orthology)	PROX2 DEPDC5 HSP90AB2P ATM HSP90AA1 HSP90AB1 HSP90AB3P	6.59e-06	268	77	7	DOID:162 (implicated_via_orthology)
Disease	colorectal cancer (is_marker_for)	TGFB2 TET2 ERCC2 GCLC ATM	5.80e-05	157	77	5	DOID:9256 (is_marker_for)
Disease	muscular atrophy (biomarker_via_orthology)	HSP90AB2P HSP90AB1 HSP90AB3P	5.95e-05	29	77	3	DOID:767 (biomarker_via_orthology)
Disease	Aicardi-Goutieres Syndrome 2	RNASEH2B SAMHD1	1.00e-04	6	77	2	C3489724
Disease	AICARDI-GOUTIERES SYNDROME 1	RNASEH2B SAMHD1	1.00e-04	6	77	2	C0796126
Disease	Aicardi Goutieres syndrome	RNASEH2B SAMHD1	1.00e-04	6	77	2	cv:C0393591
Disease	Adenocarcinoma of large intestine	DLC1 ATM CDC42BPB FBXW7	1.19e-04	96	77	4	C1319315
Disease	Pseudo-TORCH syndrome	RNASEH2B SAMHD1	1.40e-04	7	77	2	C3489725
Disease	pancreatitis (biomarker_via_orthology)	HSP90AB2P HSP90AB1 HSP90AB3P	1.46e-04	39	77	3	DOID:4989 (biomarker_via_orthology)
Disease	AICARDI-GOUTIERES SYNDROME	RNASEH2B SAMHD1	1.86e-04	8	77	2	C0393591
Disease	Aicardi-Goutieres syndrome (is_implicated_in)	RNASEH2B SAMHD1	2.39e-04	9	77	2	DOID:0050629 (is_implicated_in)
Disease	colorectal cancer (is_implicated_in)	TGFB2 PTPN13 DLC1 ATM	2.89e-04	121	77	4	DOID:9256 (is_implicated_in)
Disease	Peripheral T-Cell Lymphoma	TET2 ATM	2.98e-04	10	77	2	C0079774
Disease	pulmonary fibrosis (biomarker_via_orthology)	HSP90AB2P HSP90AB1 HSP90AB3P	3.07e-04	50	77	3	DOID:3770 (biomarker_via_orthology)
Disease	senile cataract (is_implicated_in)	ERCC2 ATM	3.64e-04	11	77	2	DOID:9669 (is_implicated_in)
Disease	neutropenia, response to gemcitabine	TGFB2 DLC1	3.64e-04	11	77	2	GO_0036272, MONDO_0001475
Disease	Colorectal Carcinoma	TET2 DNAH3 ERCC2 DLC1 SACS SNRNP200 ABCA10 FBXW7	4.89e-04	702	77	8	C0009402
Disease	tetralogy of Fallot (implicated_via_orthology)	DOCK1 DNAH5	5.99e-04	14	77	2	DOID:6419 (implicated_via_orthology)
Disease	oral squamous cell carcinoma (is_marker_for)	TET2 PTPN13 ATM	6.06e-04	63	77	3	DOID:0050866 (is_marker_for)
Disease	Neoplasm of uncertain or unknown behavior of bladder	ERCC2 ATM	6.90e-04	15	77	2	C0496930
Disease	Benign neoplasm of bladder	ERCC2 ATM	6.90e-04	15	77	2	C0154017
Disease	Carcinoma in situ of bladder	ERCC2 ATM	6.90e-04	15	77	2	C0154091
Disease	esophagus squamous cell carcinoma (is_marker_for)	TET2 ATM TET3	9.69e-04	74	77	3	DOID:3748 (is_marker_for)
Disease	methylcobalamin deficiency type cblE	SLC25A44 KCTD1 ABCA10	9.69e-04	74	77	3	MONDO_0009354
Disease	Carcinoma of bladder	ERCC2 ATM	1.00e-03	18	77	2	C0699885
Disease	intrahepatic cholangiocarcinoma (is_marker_for)	HSP90AA1 HSP90AB1	1.12e-03	19	77	2	DOID:4928 (is_marker_for)
Disease	acute myeloid leukemia (is_implicated_in)	TET2 ERCC2 SAMHD1	1.40e-03	84	77	3	DOID:9119 (is_implicated_in)
Disease	Dystonia	RNASEH2B SAMHD1 ATM	1.50e-03	86	77	3	C0013421
Disease	childhood aggressive behaviour measurement	DLC1 EIF4G2 ASB4	1.65e-03	89	77	3	EFO_0007663
Disease	lung squamous cell carcinoma (is_implicated_in)	PTPN13 ATM	1.79e-03	24	77	2	DOID:3907 (is_implicated_in)
Disease	retinitis pigmentosa (implicated_via_orthology)	CCDC66 SNRNP200	2.26e-03	27	77	2	DOID:10584 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
YLYETTLPLLKEKLE	TTF1	826	Q15361
IYDLLKDPVSLRSKA	ARHGEF10	1306	O15013
TESEEKLVYSLPLEK	ABCA10	651	Q8WWZ4
LLSLPLSLKKYLLLE	ASB4	406	Q9Y574
TTTTPLLLLYKDPDK	GPR18	151	Q14330
PDITLSKLYKLIEES	ANAPC5	71	Q9UJX4
DEYSPLLLQVKSLKE	DEPDC5	46	O75140
DTLAYIALLEEKLLP	MTX3	91	Q5HYI7
IYYEESLEPLLKTLK	VCPKMT	146	Q9H867
PSLSALIYKDEKLTV	OAZ2	51	O95190
LDKIRYESLTDPSKL	HSP90AB1	51	P08238
SLKLKLPSSYELDVL	PCGF5	181	Q86SE9
SEISLLPSDIDRYKK	GPD2	616	P43304
LSAAYTKDLLLPIKT	MTARC1	126	Q5VT66
LDKIRYESLTDPSKL	HSP90AB2P	51	Q58FF8
LDKIRYESLTDPSKL	HSP90AB3P	51	Q58FF7
LLDLPKYSSKEILSA	HERC3	1021	Q15034
LDTKLPTSELKIYAK	FSIP2	2726	Q5CZC0
LRTSKLLIPDDFKDY	KCTD1	91	Q719H9
FNLLDLPKYTEKETL	HERC4	1026	Q5GLZ8
VILSYKLDFLIPLSK	GCLC	451	P48506
YLLDPKIADLVSKEL	ERCC2	211	P18074
LLTLLSKFEDKLPED	CDC42BPB	161	Q9Y5S2
LLIVDKALEEPKYSS	EIF4G2	116	P78344
DILLTLDYPKEALKL	PLOD2	316	O00469
YKIISKLDSDIPEIF	PROX2	571	Q3B8N5
NLLSKDVLYPSLKEI	PEX19	181	P40855
LKSILEILSKSPDSY	ATM	1401	Q13315
EILSKSPDSYQKILL	ATM	1406	Q13315
LELYKEELQTKPALL	GTPBP10	261	A4D1E9
IAPLLEKLAKTSDVY	CASD1	191	Q96PB1
SEDILKLLSEYKKPE	DOCK11	561	Q5JSL3
TYLSLPSTKAELEEK	DOCK1	566	Q14185
EELLEKEKSTYPLLQ	DNAH3	846	Q8TD57
LKLKYPEENESVLLL	DNAH3	1616	Q8TD57
KELALYVLSFLEPKD	FBXW7	286	Q969H0
TELLDGKTKLILSPY	CCDC66	11	A2RUB6
YSKLLLEKTLLEEPS	CEP350	661	Q5VT06
LPSKELDYLIKFSKL	CAPRIN2	246	Q6IMN6
KLDEKDIPTRLLLSY	MS4A6E	86	Q96DS6
DPSVVLALKSLEKDY	IZUMO1	26	Q8IYV9
LDKIRYESLTDPSKL	HSP90AA1	56	P07900
KLSYTVEVLLPDKAS	SEC14L4	376	Q9UDX3
EYLKIEKVDLPLIDS	SAAL1	341	Q96ER3
LLPKIENLSYDAKLE	SACS	3481	Q9NZJ4
ELYLKLLKLEQETEP	KIF28P	826	B7ZC32
LKTLKEPTDYLTLAN	DNAH5	231	Q8TE73
LKILDYSDKQATLIP	LRRC40	401	Q9H9A6
EKLDLSYIKEELPKL	PTPN13	736	Q12923
PTLALLTEKELLLYL	SNTA1	311	Q13424
LTEKELLLYLSLPET	SNTA1	316	Q13424
IFLEILYSTDPKLKD	SAMHD1	426	Q9Y3Z3
LYSTDPKLKDAREIL	SAMHD1	431	Q9Y3Z3
EEILPSLKKDDVSIY	SLC27A2	166	O14975
LPLDISKEEILYLLK	TDRD10	41	Q5VZ19
SKEEILYLLKDFNPL	TDRD10	46	Q5VZ19
ENLDLKLTPYKVLAT	PIK3C3	661	Q8NEB9
YLSKSLEKLSPLREK	SMG7	261	Q92540
KYDEPILKFLSDVSL	NAP1L3	331	Q99457
YESLKKLSLRPELVD	SLC25A44	296	Q96H78
LYQKTEILSLEKPLL	NIF3L1	231	Q9GZT8
LLKLTALLEKYTPSN	DLC1	1036	Q96QB1
VLTYKKADTDLLPEE	SNX7	301	Q9UNH6
PTYLKDLSISIDKAE	ADGRF5	746	Q8IZF2
LDVLSLVPTDLAYLK	CNGA3	251	Q16281
EKLYKSLEQASLSPL	CNK3/IPCEF1	776	G9CGD6
VEPFKSLYLSEKILL	CNNM1	621	Q9NRU3
TLPLTSYKQELEELK	PIK3R4	61	Q99570
IELYQILKSKDLTSP	TGFB2	166	P61812
SPLKEKYIDAASELI	TMX3	161	Q96JJ7
TRKLLLLLESDPKVY	STIL	241	Q15468
VLLLPEYSSKEKLKE	UBE3A	846	Q05086
ISDYIPKELSDDLSK	RNASEH2B	216	Q5TBB1
LLKVPVSDLLLSYES	TBCE	481	Q15813
FEPKKLLDQLTDIYL	UBE4B	1146	O95155
TLSEKLDLLKLVKPY	FSBP	11	O95073
SPLKYLDTPTKSLLD	TET3	801	O43151
DLIPYLEKLSDSTLK	SNRNP200	1596	O75643
LKLLPYEQSSLLELI	WASHC4	66	Q2M389
KSLEEIYLFSLPIKE	RPS2	76	P15880
SLILDLKYVLISKPT	UBR2	476	Q8IWV8
IPLSLADKLYSELTE	TET2	1236	Q6N021
SVPKELYLSSSLKDL	USP8	6	P40818
ISEILKPNDDYLLKT	SERPINB10	96	P48595
KLPEFYDETLLRSKL	UBE3C	1056	Q15386