Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24	3.23e-15	37	105	10	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24	4.36e-15	38	105	10	GO:0070001
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	2.32e-07	11	105	4	GO:0004523
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	6.94e-07	14	105	4	GO:0003964
GeneOntologyMolecularFunction	zinc ion binding	ERVK-6 DHX58 MYCBP2 ENPP1 ENPP2 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ZFP37 ZBBX ZDHHC15 SLFN13 ERVK-8 ERVK-19 ERVK-24 TET3 SOD1	8.52e-07	891	105	18	GO:0008270
GeneOntologyMolecularFunction	phosphodiesterase I activity	ENPP1 ENPP2 FAN1	1.40e-06	5	105	3	GO:0004528
GeneOntologyMolecularFunction	endopeptidase activity	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ADAMTS12 ADGB ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24	2.73e-06	430	105	12	GO:0004175
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-7 ERVK-10 ERVK-8	4.03e-06	21	105	4	GO:0035613
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 FAN1 ERVK-8	4.22e-06	46	105	5	GO:0016893
GeneOntologyMolecularFunction	transition metal ion binding	ERVK-6 DHX58 MYCBP2 ENPP1 ENPP2 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ZFP37 ZBBX ZDHHC15 SLFN13 AGMO ERVK-8 ERVK-19 ERVK-24 TET3 SOD1	1.25e-05	1189	105	19	GO:0046914
GeneOntologyMolecularFunction	bone sialoprotein binding	ANXA2 ANXA2P2	2.74e-05	2	105	2	GO:0044730
GeneOntologyMolecularFunction	nuclease activity	ERVK-6 ENPP1 ENPP2 ERVK-7 ERVK-10 FAN1 SLFN13 ERVK-8	3.02e-05	231	105	8	GO:0004518
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	ERVK-6 DHX58 THUMPD3 ERVK-7 ERVK-10 RFC4 FAN1 DDX46 SLFN13 MOV10L1 ERVK-8 DDX23 TOP3B	3.37e-05	645	105	13	GO:0140640
GeneOntologyMolecularFunction	peptidase activity	ERVK-6 NAALAD2 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ADAMTS12 ADGB ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24	3.89e-05	654	105	13	GO:0008233
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8	4.17e-05	37	105	4	GO:0016891
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	4.64e-05	38	105	4	GO:0034061
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 ERVK-7 ERVK-10 SLFN13 ERVK-8	6.04e-05	79	105	5	GO:0004521
GeneOntologyMolecularFunction	structural molecule activity	ERVK-6 RPL35A RPS4X ERVK-7 ERVK-21 ERVK-9 ERVK-10 NEB HMCN1 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24 VCL	6.42e-05	891	105	15	GO:0005198
GeneOntologyMolecularFunction	catalytic activity, acting on RNA	ERVK-6 DHX58 THUMPD3 ERVK-7 ERVK-10 DDX46 SLFN13 MOV10L1 ERVK-8 DDX23	6.99e-05	417	105	10	GO:0140098
GeneOntologyMolecularFunction	Pyrin domain binding	NLRP7 NLRP2	8.19e-05	3	105	2	GO:0032090
GeneOntologyMolecularFunction	endonuclease activity	ERVK-6 ERVK-7 ERVK-10 FAN1 SLFN13 ERVK-8	8.28e-05	136	105	6	GO:0004519
GeneOntologyMolecularFunction	allyl-alcohol dehydrogenase activity	AKR1A1 AKR1B10	1.63e-04	4	105	2	GO:0047655
GeneOntologyMolecularFunction	phospholipase A2 inhibitor activity	ANXA2 ANXA2P2	2.71e-04	5	105	2	GO:0019834
GeneOntologyMolecularFunction	small GTPase binding	MYCBP2 ANXA2 ANXA2P2 DOCK9 CDC42BPB HPS6 VCL SOD1	2.95e-04	321	105	8	GO:0031267
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	ERVK-6 ERVK-7 ERVK-10 RFC4 FAN1 ERVK-8 TOP3B	4.71e-04	262	105	7	GO:0140097
GeneOntologyMolecularFunction	GTPase binding	MYCBP2 ANXA2 ANXA2P2 DOCK9 CDC42BPB HPS6 VCL SOD1	6.30e-04	360	105	8	GO:0051020
GeneOntologyMolecularFunction	RNA nuclease activity	ERVK-6 ERVK-7 ERVK-10 SLFN13 ERVK-8	7.62e-04	136	105	5	GO:0004540
GeneOntologyMolecularFunction	RNA helicase activity	DHX58 DDX46 MOV10L1 DDX23	7.64e-04	78	105	4	GO:0003724
GeneOntologyMolecularFunction	ATP-dependent activity, acting on RNA	DHX58 DDX46 MOV10L1 DDX23	8.40e-04	80	105	4	GO:0008186
GeneOntologyMolecularFunction	dinucleotide phosphatase activity	ENPP1 ENPP2	9.63e-04	9	105	2	GO:0004551
GeneOntologyMolecularFunction	aspartic-type endopeptidase inhibitor activity	NLRP7 NLRP2	9.63e-04	9	105	2	GO:0019828
GeneOntologyMolecularFunction	cargo receptor activity	ENPP1 ENPP2 LDLR LRP2	1.05e-03	85	105	4	GO:0038024
GeneOntologyMolecularFunction	helicase activity	DHX58 RFC4 DDX46 MOV10L1 DDX23	1.49e-03	158	105	5	GO:0004386
GeneOntologyMolecularFunction	pyrophosphatase activity	DHX58 ENPP1 ENPP2 TOR1A SRP54 RFC4 DDX46 SLFN13 MOV10L1 ARL13B DDX23 AGAP2	1.52e-03	839	105	12	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	DHX58 ENPP1 ENPP2 TOR1A SRP54 RFC4 DDX46 SLFN13 MOV10L1 ARL13B DDX23 AGAP2	1.53e-03	840	105	12	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	DHX58 ENPP1 ENPP2 TOR1A SRP54 RFC4 DDX46 SLFN13 MOV10L1 ARL13B DDX23 AGAP2	1.53e-03	840	105	12	GO:0016818
GeneOntologyMolecularFunction	interleukin-1 binding	NLRP7 NLRP2	1.75e-03	12	105	2	GO:0019966
GeneOntologyMolecularFunction	phospholipase inhibitor activity	ANXA2 ANXA2P2	2.06e-03	13	105	2	GO:0004859
GeneOntologyMolecularFunction	ATP hydrolysis activity	DHX58 TOR1A SRP54 RFC4 DDX46 SLFN13 MOV10L1 DDX23	2.29e-03	441	105	8	GO:0016887
GeneOntologyMolecularFunction	aldose reductase (NADPH) activity	AKR1A1 AKR1B10	2.39e-03	14	105	2	GO:0004032
GeneOntologyMolecularFunction	protease binding	NLRP7 ANXA2 ANXA2P2 NLRP2 LDLR	2.69e-03	181	105	5	GO:0002020
GeneOntologyMolecularFunction	microtubule minus-end binding	CAMSAP3 CAMSAP2	2.75e-03	15	105	2	GO:0051011
GeneOntologyMolecularFunction	S100 protein binding	ANXA2 ANXA2P2	2.75e-03	15	105	2	GO:0044548
GeneOntologyMolecularFunction	caspase binding	NLRP7 NLRP2	3.13e-03	16	105	2	GO:0089720
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LDLR LRP2	3.13e-03	16	105	2	GO:0005041
GeneOntologyMolecularFunction	lipase inhibitor activity	ANXA2 ANXA2P2	3.97e-03	18	105	2	GO:0055102
GeneOntologyMolecularFunction	ATP-dependent activity	DHX58 TOR1A SRP54 RFC4 DDX46 SLFN13 DNAH17 MOV10L1 DDX23	5.08e-03	614	105	9	GO:0140657
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	LDLR LRP2	5.39e-03	21	105	2	GO:0030228
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-7 ERVK-10 ERVK-8	3.89e-07	13	102	4	GO:0015074
GeneOntologyBiologicalProcess	receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2 LDLR	1.88e-05	11	102	3	GO:0090118
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein particle receptor binding	ANXA2 ANXA2P2	2.42e-05	2	102	2	GO:1905597
GeneOntologyBiologicalProcess	cell-cell fusion	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19	6.42e-05	85	102	5	GO:0140253
GeneOntologyBiologicalProcess	syncytium formation by plasma membrane fusion	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19	6.42e-05	85	102	5	GO:0000768
GeneOntologyBiologicalProcess	positive regulation of receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2	7.24e-05	3	102	2	GO:1905602
GeneOntologyBiologicalProcess	negative regulation of low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2	7.24e-05	3	102	2	GO:0032804
GeneOntologyBiologicalProcess	syncytium formation	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19	8.00e-05	89	102	5	GO:0006949
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	ERVK-6 ERVK-7 ERVK-10 ERVK-8	9.28e-05	48	102	4	GO:0000731
GeneOntologyBiologicalProcess	viral process	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ADAR LDLR ERVK-8 ERVK-19 ERVK-24	1.01e-04	464	102	10	GO:0016032
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein particle clearance	ANXA2 ANXA2P2	1.44e-04	4	102	2	GO:1905581
GeneOntologyBiologicalProcess	negative regulation of receptor catabolic process	ANXA2 ANXA2P2	1.44e-04	4	102	2	GO:2000645
GeneOntologyBiologicalProcess	positive regulation of intracellular cholesterol transport	ANXA2 ANXA2P2	1.44e-04	4	102	2	GO:0032385
GeneOntologyBiologicalProcess	positive regulation of intracellular sterol transport	ANXA2 ANXA2P2	1.44e-04	4	102	2	GO:0032382
GeneOntologyBiologicalProcess	regulation of receptor binding	ANXA2 ANXA2P2 PTPRF	2.20e-04	24	102	3	GO:1900120
GeneOntologyBiologicalProcess	regulation of low-density lipoprotein particle clearance	ANXA2 ANXA2P2 LDLR	2.20e-04	24	102	3	GO:0010988
GeneOntologyBiologicalProcess	positive regulation of plasma membrane repair	ANXA2 ANXA2P2	2.40e-04	5	102	2	GO:1905686
GeneOntologyBiologicalProcess	positive regulation of lysosomal protein catabolic process	LDLR LRP2	2.40e-04	5	102	2	GO:1905167
GeneOntologyBiologicalProcess	regulation of low-density lipoprotein particle receptor binding	ANXA2 ANXA2P2	2.40e-04	5	102	2	GO:1905595
GeneOntologyBiologicalProcess	positive regulation of intracellular lipid transport	ANXA2 ANXA2P2	2.40e-04	5	102	2	GO:0032379
GeneOntologyBiologicalProcess	DNA-templated DNA replication	ERVK-6 CAMSAP3 ERVK-7 ERVK-10 RFC4 ERVK-8	2.58e-04	178	102	6	GO:0006261
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein receptor activity	ANXA2 ANXA2P2	3.59e-04	6	102	2	GO:1905599
GeneOntologyBiologicalProcess	regulation of receptor recycling	ANXA2 ANXA2P2 LDLR	4.77e-04	31	102	3	GO:0001919
GeneOntologyBiologicalProcess	positive regulation of protein catabolic process in the vacuole	LDLR LRP2	5.00e-04	7	102	2	GO:1904352
GeneOntologyBiologicalProcess	regulation of low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2	5.00e-04	7	102	2	GO:0032803
GeneOntologyBiologicalProcess	low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2	5.00e-04	7	102	2	GO:0032802
GeneOntologyBiologicalProcess	low-density lipoprotein receptor particle metabolic process	ANXA2 ANXA2P2	5.00e-04	7	102	2	GO:0032799
GeneOntologyBiologicalProcess	neuron projection development	TANC2 EVL MYCBP2 ENPP1 CAMSAP3 TOR1A ZDHHC15 PTPRF PTPRS CNTN5 LRP2 PRDM12 CAMSAP2 ALK VCL SOD1	5.53e-04	1285	102	16	GO:0031175
GeneOntologyCellularComponent	actomyosin	EVL CDC42BPA ANXA2 ANXA2P2 CDC42BPB VCL	2.48e-05	117	103	6	GO:0042641
GeneOntologyCellularComponent	AnxA2-p11 complex	ANXA2 ANXA2P2	7.19e-05	3	103	2	GO:1990665
GeneOntologyCellularComponent	PCSK9-AnxA2 complex	ANXA2 ANXA2P2	7.19e-05	3	103	2	GO:1990667
GeneOntologyCellularComponent	myelin sheath adaxonal region	ANXA2 ANXA2P2	4.97e-04	7	103	2	GO:0035749
GeneOntologyCellularComponent	microtubule minus-end	CAMSAP3 CAMSAP2	4.97e-04	7	103	2	GO:0036449
Domain	P-loop_NTPase	TANC2 TPST1 DHX58 NLRP7 APAF1 TOR1A SRP54 RFC4 NLRP2 DDX46 SLFN13 MOV10L1 ARL13B DDX23 AGAP2	1.20e-05	848	90	15	IPR027417
Domain	-	TPST1 DHX58 NLRP7 APAF1 TOR1A SRP54 RFC4 NLRP2 DDX46 SLFN13 MOV10L1 ARL13B DDX23 AGAP2	1.26e-05	746	90	14	3.40.50.300
Domain	KELK	CDC42BPA CDC42BPB	2.30e-05	2	90	2	IPR031597
Domain	KELK	CDC42BPA CDC42BPB	2.30e-05	2	90	2	PF15796
Domain	CAMSAP_CC1	CAMSAP3 CAMSAP2	6.87e-05	3	90	2	PF17095
Domain	CAMSAP_CKK	CAMSAP3 CAMSAP2	6.87e-05	3	90	2	SM01051
Domain	PRC_barrel-like	CAMSAP3 CAMSAP2	6.87e-05	3	90	2	IPR011033
Domain	CKK_domain	CAMSAP3 CAMSAP2	6.87e-05	3	90	2	IPR014797
Domain	CAMSAP_CKK	CAMSAP3 CAMSAP2	6.87e-05	3	90	2	PF08683
Domain	CAMSAP_CC1	CAMSAP3 CAMSAP2	6.87e-05	3	90	2	IPR031372
Domain	CAMSAP	CAMSAP3 CAMSAP2	6.87e-05	3	90	2	IPR032940
Domain	CKK	CAMSAP3 CAMSAP2	6.87e-05	3	90	2	PS51508
Domain	Myotonic_dystrophy_kinase_coil	CDC42BPA CDC42BPB	1.37e-04	4	90	2	IPR014930
Domain	Myotonic_dystrophy_kinase_coil	CDC42BPA CDC42BPB	1.37e-04	4	90	2	PD011252
Domain	DMPK_coil	CDC42BPA CDC42BPB	1.37e-04	4	90	2	PF08826
Domain	PWI	RBM26 RBM27	2.27e-04	5	90	2	PF01480
Domain	-	RBM26 RBM27	2.27e-04	5	90	2	1.20.1390.10
Domain	Somatomedin_B_chordata	ENPP1 ENPP2	2.27e-04	5	90	2	IPR020436
Domain	PWI_dom	RBM26 RBM27	2.27e-04	5	90	2	IPR002483
Domain	DNA/RNA_non-sp_Endonuclease	ENPP1 ENPP2	3.40e-04	6	90	2	IPR001604
Domain	-	ENPP1 ENPP2	3.40e-04	6	90	2	3.40.570.10
Domain	Endonuclease_NS	ENPP1 ENPP2	3.40e-04	6	90	2	PF01223
Domain	Extracellular_endonuc_su_A	ENPP1 ENPP2	3.40e-04	6	90	2	IPR020821
Domain	NUC	ENPP1 ENPP2	3.40e-04	6	90	2	SM00477
Domain	Endonuclease_NS	ENPP1 ENPP2	3.40e-04	6	90	2	SM00892
Domain	CAMSAP_CH	CAMSAP3 CAMSAP2	4.75e-04	7	90	2	PF11971
Domain	E-NPP	ENPP1 ENPP2	4.75e-04	7	90	2	IPR024873
Domain	Epimerase_deHydtase	NDUFA9 TGDS	4.75e-04	7	90	2	IPR001509
Domain	CAMSAP_CH	CAMSAP3 CAMSAP2	4.75e-04	7	90	2	IPR022613
Domain	Epimerase	NDUFA9 TGDS	4.75e-04	7	90	2	PF01370
Domain	Somatomedin_B	ENPP1 ENPP2	6.31e-04	8	90	2	PF01033
Domain	SO	ENPP1 ENPP2	8.09e-04	9	90	2	SM00201
Domain	Somatomedin_B_dom	ENPP1 ENPP2	1.01e-03	10	90	2	IPR001212
Domain	ALDOKETO_REDUCTASE_1	AKR1A1 AKR1B10	1.01e-03	10	90	2	PS00798
Domain	SMB_1	ENPP1 ENPP2	1.01e-03	10	90	2	PS00524
Domain	ALDOKETO_REDUCTASE_2	AKR1A1 AKR1B10	1.01e-03	10	90	2	PS00062
Domain	ALDOKETO_REDUCTASE_3	AKR1A1 AKR1B10	1.01e-03	10	90	2	PS00063
Domain	Phosphodiest/P_Trfase	ENPP1 ENPP2	1.01e-03	10	90	2	IPR002591
Domain	SMB_2	ENPP1 ENPP2	1.01e-03	10	90	2	PS50958
Domain	Aldo/ket_reductase_CS	AKR1A1 AKR1B10	1.01e-03	10	90	2	IPR018170
Domain	Aldo/keto_reductase	AKR1A1 AKR1B10	1.01e-03	10	90	2	IPR020471
Domain	Phosphodiest	ENPP1 ENPP2	1.01e-03	10	90	2	PF01663
Domain	Filamin	MYCBP2 POGLUT2	1.23e-03	11	90	2	PF00630
Domain	FILAMIN_REPEAT	MYCBP2 POGLUT2	1.23e-03	11	90	2	PS50194
Domain	Filamin/ABP280_rpt	MYCBP2 POGLUT2	1.23e-03	11	90	2	IPR001298
Domain	Filamin/ABP280_repeat-like	MYCBP2 POGLUT2	1.23e-03	11	90	2	IPR017868
Domain	-	LDLR LRP2 ALK	1.41e-03	46	90	3	4.10.400.10
Domain	LDLRA_1	LDLR LRP2 ALK	1.60e-03	48	90	3	PS01209
Domain	LDrepeatLR_classA_rpt	LDLR LRP2 ALK	1.70e-03	49	90	3	IPR002172
Domain	LDLa	LDLR LRP2 ALK	1.70e-03	49	90	3	SM00192
Domain	LDLRA_2	LDLR LRP2 ALK	1.70e-03	49	90	3	PS50068
Domain	Ldl_recept_b	LDLR LRP2	2.01e-03	14	90	2	PF00058
Domain	LDLRB	LDLR LRP2	2.01e-03	14	90	2	PS51120
Domain	CNH	CDC42BPA CDC42BPB	2.01e-03	14	90	2	SM00036
Domain	Ig_I-set	SIGLEC8 PTPRF HMCN1 PTPRS CNTN5	2.26e-03	190	90	5	IPR013098
Domain	I-set	SIGLEC8 PTPRF HMCN1 PTPRS CNTN5	2.26e-03	190	90	5	PF07679
Domain	LY	LDLR LRP2	2.31e-03	15	90	2	SM00135
Domain	CNH	CDC42BPA CDC42BPB	2.31e-03	15	90	2	PF00780
Domain	CNH	CDC42BPA CDC42BPB	2.31e-03	15	90	2	PS50219
Domain	CNH_dom	CDC42BPA CDC42BPB	2.31e-03	15	90	2	IPR001180
Domain	LDLR_classB_rpt	LDLR LRP2	2.31e-03	15	90	2	IPR000033
Domain	-	AKR1A1 AKR1B10	2.64e-03	16	90	2	3.20.20.100
Domain	PBD	CDC42BPA CDC42BPB	2.64e-03	16	90	2	SM00285
Domain	NADP_OxRdtase_dom	AKR1A1 AKR1B10	2.98e-03	17	90	2	IPR023210
Domain	Aldo_ket_red	AKR1A1 AKR1B10	2.98e-03	17	90	2	PF00248
Domain	Aldo/ket_red/Kv-b	AKR1A1 AKR1B10	2.98e-03	17	90	2	IPR001395
Domain	RCC1	MYCBP2 NEK9	4.12e-03	20	90	2	PF00415
Domain	CRIB	CDC42BPA CDC42BPB	4.12e-03	20	90	2	PS50108
Domain	RCC1_1	MYCBP2 NEK9	4.54e-03	21	90	2	PS00625
Domain	RCC1_2	MYCBP2 NEK9	4.54e-03	21	90	2	PS00626
Domain	RCC1_3	MYCBP2 NEK9	4.54e-03	21	90	2	PS50012
Domain	CRIB_dom	CDC42BPA CDC42BPB	4.54e-03	21	90	2	IPR000095
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7 ERVK-21 ERVK-18 ERVK-19	2.63e-13	5	108	5	12629516
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24	3.96e-13	94	108	10	21542922
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-21 ERVK-9 ERVK-10 ERVK-18 ERVK-25 ERVK-24	1.40e-11	18	108	6	18664271
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-10 ERVK-24	8.79e-11	4	108	4	10469592
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19	2.05e-10	12	108	5	14557543
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-18 ERVK-19	2.91e-08	3	108	3	10516026
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TANC2 CRYBG2 CDC42BPA MYCBP2 DOCK9 CDC42BPB LDLR C6orf132 PPP1R26 KMT2D PTPRF PTPRS TTLL4 HPS6 HMGXB3 MBD5 TOP3B	5.51e-08	1105	108	17	35748872
Pubmed	Hspb1 protects against severe acute pancreatitis by attenuating apoptosis and ferroptosis via interacting with Anxa2 to restore the antioxidative activity of Prdx1.	ANXA2 ANXA2P2 PRDX1	1.16e-07	4	108	3	38481805
Pubmed	Annexin A2 is a natural extrahepatic inhibitor of the PCSK9-induced LDL receptor degradation.	ANXA2 ANXA2P2 LDLR	1.16e-07	4	108	3	22848640
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-10 ERVK-19	1.16e-07	4	108	3	7983737
Pubmed	Annexin A2 is a C-terminal PCSK9-binding protein that regulates endogenous low density lipoprotein receptor levels.	ANXA2 ANXA2P2 LDLR	1.16e-07	4	108	3	18799458
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	RPL35A MYCBP2 ACAT2 ANXA2 RPS4X RBM26 CAMSAP3 AKR1A1 RFC4 ADAR NEK9 DDX46 RBM27 PRDX1 VCL SOD1	5.34e-07	1149	108	16	35446349
Pubmed	Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.	ERVK-6 ERVK-9 ERVK-19	5.78e-07	6	108	3	15063128
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	MYCBP2 ANXA2 RBM26 ADAR NEK9 GTF2F2 KMT2D DDX46 RBM27 PRDX1 VCL	1.19e-06	549	108	11	38280479
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	ANXA2 ANXA2P2 RBM26 RFC4 ADAR DDX46 RBM27 PRDX1 DDX23	1.23e-06	340	108	9	24332808
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	RBM26 SRP54 PRPF38B RFC4 ADAR NEK9 GTF2F2 DDX46 RBM27 PRDX1 CAMSAP2 VCL SOD1 KNL1	1.24e-06	934	108	14	33916271
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TANC2 EVL RPL35A ANXA2 RPS4X ANXA2P2 CAMSAP3 NDUFA9 CDC42BPB GJA3 PTPRS AKR1B10 PRDX1 CAMSAP2 VCL SOD1 AGAP2	2.01e-06	1431	108	17	37142655
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	TANC2 EVL CDC42BPA MYCBP2 ANXA2 RPS4X ANXA2P2 DOCK9 CAMSAP3 PRPF38B NDUFA9 CDC42BPB PRDX1 CAMSAP2 AGAP2	2.48e-06	1139	108	15	36417873
Pubmed	Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.	ERVK-6 ERVK-21 ERVK-19	3.44e-06	10	108	3	12970426
Pubmed	NLRP2 controls age-associated maternal fertility.	NLRP7 NLRP2	9.55e-06	2	108	2	27881734
Pubmed	CAMSAP3 maintains neuronal polarity through regulation of microtubule stability.	CAMSAP3 CAMSAP2	9.55e-06	2	108	2	30190432
Pubmed	Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy.	ANXA2 ANXA2P2	9.55e-06	2	108	2	19536308
Pubmed	Renal cell carcinoma with novel VCL-ALK fusion: new representative of ALK-associated tumor spectrum.	ALK VCL	9.55e-06	2	108	2	21076462
Pubmed	Annexin A2 modulates radiation-sensitive transcriptional programming and cell fate.	ANXA2 ANXA2P2	9.55e-06	2	108	2	23148505
Pubmed	CAMSAP2 and CAMSAP3 localize at microtubule intersections to regulate the spatial distribution of microtubules.	CAMSAP3 CAMSAP2	9.55e-06	2	108	2	37567766
Pubmed	Reproductive Outcomes from Maternal Loss of Nlrp2 Are Not Improved by IVF or Embryo Transfer Consistent with Oocyte-Specific Defect.	NLRP7 NLRP2	9.55e-06	2	108	2	33090377
Pubmed	ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.	ANXA2 ANXA2P2	9.55e-06	2	108	2	38290972
Pubmed	Cloning and chromosomal localization of human Cdc42-binding protein kinase beta.	CDC42BPA CDC42BPB	9.55e-06	2	108	2	10198171
Pubmed	The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats.	ANXA2 ANXA2P2	9.55e-06	2	108	2	3013423
Pubmed	Activation of Annexin A2 signaling at the blood-brain barrier in a mouse model of multiple sclerosis.	ANXA2 ANXA2P2	9.55e-06	2	108	2	35064931
Pubmed	Complex Roles of Annexin A2 in Host Blood-Brain Barrier Invasion by Cryptococcus neoformans.	ANXA2 ANXA2P2	9.55e-06	2	108	2	28130864
Pubmed	Localization of annexin II in the paranodal regions and Schmidt-Lanterman incisures in the peripheral nervous system.	ANXA2 ANXA2P2	9.55e-06	2	108	2	17549680
Pubmed	Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in mice.	ANXA2 ANXA2P2	9.55e-06	2	108	2	39384746
Pubmed	Annexin A2 mediates up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells.	ANXA2 ANXA2P2	9.55e-06	2	108	2	20826156
Pubmed	Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue.	ANXA2 ANXA2P2	9.55e-06	2	108	2	27468426
Pubmed	Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice.	LDLR AKR1B10	9.55e-06	2	108	2	16127462
Pubmed	Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis.	ANXA2 ANXA2P2	9.55e-06	2	108	2	19841537
Pubmed	Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice.	ANXA2 ANXA2P2	9.55e-06	2	108	2	27389701
Pubmed	Crystal structure of autotaxin and insight into GPCR activation by lipid mediators.	ENPP1 ENPP2	9.55e-06	2	108	2	21240269
Pubmed	A family of RS domain proteins with novel subcellular localization and trafficking.	RBM26 RBM27	9.55e-06	2	108	2	15741184
Pubmed	Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation.	ANXA2 ANXA2P2	9.55e-06	2	108	2	17360942
Pubmed	Annexin A2 regulates phagocytosis of photoreceptor outer segments in the mouse retina.	ANXA2 ANXA2P2	9.55e-06	2	108	2	19587120
Pubmed	Characterization of the interaction of phorbol esters with the C1 domain of MRCK (myotonic dystrophy kinase-related Cdc42 binding kinase) alpha/beta.	CDC42BPA CDC42BPB	9.55e-06	2	108	2	18263588
Pubmed	Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate.	ANXA2 ANXA2P2	9.55e-06	2	108	2	19022301
Pubmed	Suppressing NLRP2 expression accelerates hepatic steatosis: A mechanism involving inflammation and oxidative stress.	NLRP7 NLRP2	9.55e-06	2	108	2	30454891
Pubmed	Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury.	ANXA2 ANXA2P2	9.55e-06	2	108	2	38253182
Pubmed	Nezha/CAMSAP3 and CAMSAP2 cooperate in epithelial-specific organization of noncentrosomal microtubules.	CAMSAP3 CAMSAP2	9.55e-06	2	108	2	23169647
Pubmed	Apaf1 mediates apoptosis and mitochondrial damage induced by mutant human SOD1s typical of familial amyotrophic lateral sclerosis.	APAF1 SOD1	9.55e-06	2	108	2	16046141
Pubmed	NLRP2 inflammasome in dorsal root ganglion as a novel molecular platform that produces inflammatory pain hypersensitivity.	NLRP7 NLRP2	9.55e-06	2	108	2	31162334
Pubmed	Annexin A2 is a novel cellular redox regulatory protein involved in tumorigenesis.	ANXA2 ANXA2P2	9.55e-06	2	108	2	22185818
Pubmed	Primary cilia are specialized calcium signalling organelles.	PKD2L1 ARL13B	9.55e-06	2	108	2	24336288
Pubmed	A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events.	ANXA2 ANXA2P2	9.55e-06	2	108	2	21486955
Pubmed	NLRP2 is highly expressed in a mouse model of ischemic stroke.	NLRP7 NLRP2	9.55e-06	2	108	2	27693696
Pubmed	Lipid raft endocytosis and exosomal transport facilitate extracellular trafficking of annexin A2.	ANXA2 ANXA2P2	9.55e-06	2	108	2	21737841
Pubmed	Regulation of the low-dose radiation paracrine-specific anchorage-independent growth response by annexin A2.	ANXA2 ANXA2P2	9.55e-06	2	108	2	19580511
Pubmed	VCL-ALK renal cell carcinoma in children with sickle-cell trait: the eighth sickle-cell nephropathy?	ALK VCL	9.55e-06	2	108	2	24698962
Pubmed	A genetic association study of NLRP2 and NLRP7 genes in idiopathic recurrent miscarriage.	NLRP7 NLRP2	9.55e-06	2	108	2	23360675
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	9.55e-06	2	108	2	9060628
Pubmed	Selenomethionine promotes ANXA2 phosphorylation for proliferation and protein synthesis of myoblasts and skeletal muscle growth.	ANXA2 ANXA2P2	9.55e-06	2	108	2	36739096
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	9.55e-06	2	108	2	9460924
Pubmed	Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia.	ANXA2 ANXA2P2	9.55e-06	2	108	2	22517898
Pubmed	Anxa2 gene silencing attenuates obesity-induced insulin resistance by suppressing the NF-κB signaling pathway.	ANXA2 ANXA2P2	9.55e-06	2	108	2	30462534
Pubmed	Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis.	ANXA2 ANXA2P2	9.55e-06	2	108	2	38092984
Pubmed	Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.	ANXA2 ANXA2P2	9.55e-06	2	108	2	21572519
Pubmed	Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice.	ANXA2 ANXA2P2	9.55e-06	2	108	2	21788340
Pubmed	The Membrane Phospholipid Binding Protein Annexin A2 Promotes Phagocytosis and Nonlytic Exocytosis of Cryptococcus neoformans and Impacts Survival in Fungal Infection.	ANXA2 ANXA2P2	9.55e-06	2	108	2	27371724
Pubmed	Annexin A2 Deficiency Exacerbates Neuroinflammation and Long-Term Neurological Deficits after Traumatic Brain Injury in Mice.	ANXA2 ANXA2P2	9.55e-06	2	108	2	31817350
Pubmed	Nlrp2, a maternal effect gene required for early embryonic development in the mouse.	NLRP7 NLRP2	9.55e-06	2	108	2	22295082
Pubmed	ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3.	ANXA2 ANXA2P2	9.55e-06	2	108	2	37832154
Pubmed	Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice.	ANXA2 ANXA2P2	9.55e-06	2	108	2	30902828
Pubmed	Cell surface translocation of annexin A2 facilitates glutamate-induced extracellular proteolysis.	ANXA2 ANXA2P2	9.55e-06	2	108	2	24742684
Pubmed	Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections.	ANXA2 ANXA2P2	9.55e-06	2	108	2	32687500
Pubmed	TET3 boosts hepatocyte autophagy and impairs non-alcoholic fatty liver disease by increasing ENPP1 promoter hypomethylation.	ENPP1 TET3	9.55e-06	2	108	2	38582229
Pubmed	Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.	ANXA2 ANXA2P2	9.55e-06	2	108	2	22453828
Pubmed	Agents that bind annexin A2 suppress ocular neovascularization.	ANXA2 ANXA2P2	9.55e-06	2	108	2	20607799
Pubmed	CAMSAP3 facilitates basal body polarity and the formation of the central pair of microtubules in motile cilia.	CAMSAP3 CAMSAP2	9.55e-06	2	108	2	32482850
Pubmed	Substrate-specifying determinants of the nucleotide pyrophosphatases/phosphodiesterases NPP1 and NPP2.	ENPP1 ENPP2	9.55e-06	2	108	2	15096095
Pubmed	A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study.	ANXA2 ANXA2P2	9.55e-06	2	108	2	31253864
Pubmed	Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.	ERVK-6 ERVK-18	9.55e-06	2	108	2	11672541
Pubmed	Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo.	ANXA2 ANXA2P2	9.55e-06	2	108	2	19628708
Pubmed	Annexin A2 binds to the localization signal in the 3' untranslated region of c-myc mRNA.	ANXA2 ANXA2P2	9.55e-06	2	108	2	15654879
Pubmed	Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis.	ANXA2 ANXA2P2	9.55e-06	2	108	2	20847146
Pubmed	SRF phosphorylation by glycogen synthase kinase-3 promotes axon growth in hippocampal neurons.	ANXA2 ANXA2P2 VCL	1.29e-05	15	108	3	24623780
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	MACC1 RPL35A CDC42BPA RBM26 CAMSAP3 SRP54 PRPF38B NDUFA9 YES1 CDC42BPB C6orf132 GTF2F2 DDX46 RBM27 MCRS1 CAMSAP2	1.55e-05	1497	108	16	31527615
Pubmed	The DNA sequence and analysis of human chromosome 13.	MYCBP2 DOCK9 RBM26 GJA3 TGDS POGLUT2	1.58e-05	170	108	6	15057823
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	CDC42BPA MYCBP2 RPS4X YES1 NEK9 KMT2D HPS6	1.95e-05	264	108	7	32814769
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	CDC42BPA ANXA2 SELENOH RBM26 SRP54 PRPF38B RFC4 CDC42BPB DDX46 RBM27 AKR1B10 DDX23 NKTR ALK SOD1	2.25e-05	1371	108	15	36244648
Pubmed	PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke.	ANXA2 ANXA2P2 LDLR	2.30e-05	18	108	3	21518694
Pubmed	STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.	ANXA2 ANXA2P2	2.86e-05	3	108	2	35098646
Pubmed	Mosaic moles and non-familial biparental moles are not caused by mutations in NLRP7, NLRP2 or C6orf221.	NLRP7 NLRP2	2.86e-05	3	108	2	22909446
Pubmed	Loss of the Maternal Effect Gene Nlrp2 Alters the Transcriptome of Ovulated Mouse Oocytes and Impacts Expression of Histone Demethylase KDM1B.	NLRP7 NLRP2	2.86e-05	3	108	2	36976514
Pubmed	The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.	ANXA2 ANXA2P2	2.86e-05	3	108	2	35413401
Pubmed	Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases.	ANXA2 ANXA2P2	2.86e-05	3	108	2	28694388
Pubmed	High Podocalyxin levels promote cell viability partially through up-regulation of Annexin A2.	ANXA2 ANXA2P2	2.86e-05	3	108	2	27470587
Pubmed	Maternal variants in NLRP and other maternal effect proteins are associated with multilocus imprinting disturbance in offspring.	NLRP7 NLRP2	2.86e-05	3	108	2	29574422
Pubmed	Annexins--unique membrane binding proteins with diverse functions.	ANXA2 ANXA2P2	2.86e-05	3	108	2	15169834
Pubmed	Annexin A2 reduces PCSK9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9.	ANXA2 ANXA2P2	2.86e-05	3	108	2	24808179
Pubmed	LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.	PTPRF PTPRS	2.86e-05	3	108	2	31985401
Pubmed	The Annexin a2 Promotes Development in Arthritis through Neovascularization by Amplification Hedgehog Pathway.	ANXA2 ANXA2P2	2.86e-05	3	108	2	26963384
Pubmed	Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.	PTPRF PTPRS	2.86e-05	3	108	2	20139422
Interaction	ARHGEF2 interactions	EVL CDC42BPA MYCBP2 SELENOH SRP54 PTPRF PRDX1 CAMSAP2 TOP3B ALK VCL	5.86e-08	256	100	11	int:ARHGEF2
Interaction	BAP1 interactions	RPL35A MYCBP2 ACAT2 ANXA2 RPS4X RBM26 CAMSAP3 AKR1A1 RFC4 ADAR NEK9 DDX46 RBM27 ALDH1L2 DHODH PRDX1 MCRS1 MBD5 TOP3B VCL SOD1	1.52e-06	1314	100	21	int:BAP1
Interaction	LINC02910 interactions	RBM26 PRPF38B GTF2F2 DDX46 RBM27 TOP3B	7.81e-06	95	100	6	int:LINC02910
Interaction	IGFL3 interactions	MYCBP2 PRPF38B LDLR VWDE LRP2	3.57e-05	75	100	5	int:IGFL3
Interaction	SETD1B interactions	RBM26 LDLR KMT2D MCRS1 TOP3B	3.57e-05	75	100	5	int:SETD1B
Interaction	ANAPC15 interactions	RBM26 PRPF38B GTF2F2 DDX46 PRDX1 TOP3B	4.27e-05	128	100	6	int:ANAPC15
Interaction	PSENEN interactions	RBM26 PRPF38B GTF2F2 DDX46 TOP3B	5.17e-05	81	100	5	int:PSENEN
Cytoband	12q13.12	KMT2D DDX23 MCRS1	9.78e-05	38	107	3	12q13.12
Cytoband	11q22.1	CNTN5 ERVK-25	4.81e-04	14	107	2	11q22.1
Cytoband	Ensembl 112 genes in cytogenetic band chr7p21	MACC1 VWDE AGMO	1.21e-03	89	107	3	chr7p21
Cytoband	12q14.1	ERVK-21 AGAP2	1.96e-03	28	107	2	12q14.1
GeneFamily	Low density lipoprotein receptors	LDLR LRP2	9.97e-04	13	66	2	634
GeneFamily	Aldo-keto reductases	AKR1A1 AKR1B10	1.34e-03	15	66	2	399
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRF PTPRS	2.64e-03	21	66	2	813
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	PTPRF HMCN1 PTPRS CNTN5	2.84e-03	161	66	4	593
GeneFamily	NLR family	NLRP7 NLRP2	3.73e-03	25	66	2	666
GeneFamily	Pyrin domain containing\|Pyrin and HIN domain family	NLRP7 NLRP2	3.73e-03	25	66	2	994
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	RBM26 CAMSAP3 PPP1R26 KNL1	4.32e-03	181	66	4	694
Coexpression	TABULA_MURIS_SENIS_MESENTERIC_ADIPOSE_TISSUE_B_CELL_AGEING	MYCBP2 ANXA2 ANXA2P2 RBM26 SOD1	1.30e-05	82	96	5	MM3777
Coexpression	ZHONG_SECRETOME_OF_LUNG_CANCER_AND_MACROPHAGE	ANXA2 ENPP2 ANXA2P2 AKR1A1 PRDX1	1.63e-05	86	96	5	MM1209
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAALAD2 MYCBP2 ENPP2 SRP54 NEB OLFML3 NKTR	2.56e-07	195	98	7	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DHX58 ENPP2 CCDC71 CAMSAP2 KNL1 AGAP2	2.03e-06	169	98	6	c8691c4f707d46b2865fe46eabe24ea4d03c7b43
ToppCell	(1)_Control_(PBS)-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)\|(1)_Control_(PBS) / Stress and Cell class	RPL35A ENPP1 ENPP2 OLFML3 PTPRS PRDX1	2.66e-06	177	98	6	d9e5ac5b8949a77e88e8094079167e4cf2c1bbd1
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|normal_Lung / Location, Cell class and cell subclass	ENPP1 OLFML3 ADAMTS12 HMCN1 ALDH1L2 MOV10L1	3.32e-06	184	98	6	0b336489c10e8c3c957795dd845454f03404382b
ToppCell	NS-critical-d_16-33-Myeloid-Monocyte-derived_DC\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANXA2 RPS4X ENPP2 AKR1A1 OLFML3 PRDX1	3.76e-06	188	98	6	08eb1e4b719af53c52895557523d0a1b7421d849
ToppCell	Monocytes-Tissue-resident_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	TANC2 MACC1 SIGLEC8 ENPP1 OLFML3 CAMSAP2	4.37e-06	193	98	6	198552810dcac8d0ca63a78badd6702b49ff6edf
ToppCell	NS-critical-d_07-13-Epithelial-Secretory-diff\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RPL35A ANXA2 RPS4X AKR1A1 AKR1B10 PRDX1	5.36e-06	200	98	6	6a76c8e3d937a9c54eb81cab23b8a898f9600de1
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NAALAD2 OLFML3 HPS6 MCRS1 VCL	4.03e-05	173	98	5	ab6d3507301038f944ad59ccd848b5e6eeb76d04
ToppCell	10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-HSC/MPP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MACC1 RPS4X ZBBX ZDHHC15 PRDX1	4.03e-05	173	98	5	34357f0e22c4b6d84582492c82c1ea733ca8477d
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	CRYBG2 ACAT2 THUMPD3 APAF1 CDC42BPB	4.26e-05	175	98	5	da191dfb8a7f976a632a3a0b923942ab54f5c8c1
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CDC42BPA ENPP1 CDC42BPB POGLUT2 MBD5	4.50e-05	177	98	5	946803293a7955116c80f403e99e4093e798ca3f
ToppCell	Ciliated_cells-B-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	ZBBX ADGB SLFN13 CNTN5 VWA3B	5.13e-05	182	98	5	e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RPL35A RPS4X AKR1A1 PRDX1 SOD1	5.55e-05	185	98	5	8b381706b656d366b63adb9703db1c3dc796b3f8
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R26 ADGB HPS6 C11orf91 IFT122	5.69e-05	186	98	5	adba5647a2feaba8e361dc1020d2f2dc4ce36b16
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	LANCL3 MACC1 VWDE PTPRF LRP2	5.69e-05	186	98	5	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 MACC1 ANXA2 C6orf132 HRH1	5.84e-05	187	98	5	87b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 MACC1 ANXA2 C6orf132 HRH1	5.84e-05	187	98	5	42a1267bfc27b4460b8409ada580a87c4385841c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 MACC1 ANXA2 C6orf132 HRH1	5.84e-05	187	98	5	64afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCell	COVID-19-kidney-Stressed_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	ENPP1 ENPP2 AGMO LRP2 SOD1	5.84e-05	187	98	5	acd305475f3609800af0d7bc68d83ef41228080b
ToppCell	Monocytes-Tissue-resident_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	TANC2 SIGLEC8 ENPP1 OLFML3 CAMSAP2	6.30e-05	190	98	5	07215e8f292cb54c670037aaf28393cddbe5548c
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CDC42BPA ENPP2 DOCK9 HMCN1 HRH1	6.30e-05	190	98	5	f6c38d197fd9d69a4f97cb2e72cd4747984c1a86
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TANC2 MACC1 ACAT2 PTPRF LRP2	6.61e-05	192	98	5	7ccdb977320d09f21e70e7718ead73eeb56d0c48
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	ANXA2 LDLR C6orf132 HRH1 PITPNB	6.61e-05	192	98	5	8b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TANC2 MACC1 ACAT2 PTPRF LRP2	6.61e-05	192	98	5	bfc68af68fdb99ddfe4add49671e4b4c26e6f962
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP2 NEB LDLR PTPRF NKTR	6.78e-05	193	98	5	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP2 NEB LDLR PTPRF NKTR	6.78e-05	193	98	5	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	droplet-Tongue-Unstain-18m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS4X SELENOH RFC4 PRDX1 SOD1	6.78e-05	193	98	5	63205026e20cf2c7bfb7d08bba48d5df7976ccca
ToppCell	droplet-Pancreas-Endocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP2 NEB LDLR PTPRF NKTR	6.95e-05	194	98	5	3a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP2 NEB LDLR PTPRF NKTR	6.95e-05	194	98	5	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NAALAD2 RPL35A ENPP2 OLFML3 ADAMTS12	6.95e-05	194	98	5	a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCell	MS-CD4-memory_CD4\|MS / Condition, Cell_class and T cell subcluster	EVL CRYBG2 RPL35A ANXA2 RPS4X	7.12e-05	195	98	5	41ef1304800eda995df88c6057e9835ea31e9125
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NAALAD2 ENPP2 ADAMTS12 SLFN13 MBD5	7.12e-05	195	98	5	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	severe-Myeloid-CD16_Monocytes\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	EVL ANXA2 RPS4X PRDX1 SOD1	7.12e-05	195	98	5	5badcfdeed2fb7453a9c144506ca91c5475cd35f
ToppCell	CTRL\|World / Disease state, Lineage and Cell class	EVL MACC1 AKR1A1 PRDX1 SOD1	7.12e-05	195	98	5	cad77cdc6e0aa0875eff5ecd3805a6cf056d729d
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	NAALAD2 ADAMTS12 HMCN1 PTPRS AGMO	7.12e-05	195	98	5	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKR1A1 C6orf132 PTPRF AKR1B10 PRDX1	7.47e-05	197	98	5	8623972c7a70b3565b7a3a4afe93f1e012008201
ToppCell	NS-critical-d_07-13-Myeloid-Monocyte-derived_DC\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RPL35A RPS4X PKD2L1 OLFML3 PRDX1	7.47e-05	197	98	5	97b73eb1f9e655b7d9f616880b3756ffd5a44c64
ToppCell	control-Myeloid-CD16_Monocytes\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	EVL RPL35A ANXA2 RPS4X SOD1	7.47e-05	197	98	5	cdb2866d5a8fbf39847309124479ad49c88852d4
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Naive_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	EVL RPL35A RPS4X DOCK9 NKTR	7.47e-05	197	98	5	836dd8110d5689f944ad1d301def38c32278b5b5
ToppCell	severe-Myeloid-CD14_Monocytes_3\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RPL35A ANXA2 RPS4X AKR1A1 PRDX1	7.65e-05	198	98	5	cb8f099cf4ed320615b1c60ddab86b89d8db9a43
ToppCell	11.5-Airway-Mesenchymal-Mesenchyme_RSPO2+\|Airway / Age, Tissue, Lineage and Cell class	RPL35A RPS4X ENPP2 OLFML3 ADAMTS12	7.65e-05	198	98	5	23783572c22c24d9fb8e14dc1f3852d2094157df
ToppCell	PBMC_fresh-frozen\|World / Compartment, severity and other cell annotations on 10x 3' data (130k)	EVL RPL35A MYCBP2 RPS4X NKTR	7.65e-05	198	98	5	dcc223a0396b8b673e4ed8c6733ec6cd74e9a03a
ToppCell	mild-Myeloid-CD16_Monocytes\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	EVL RPL35A ANXA2 RPS4X SOD1	7.65e-05	198	98	5	ba97ff6e9d400b53ad013dce54afd7154a0f4fc9
ToppCell	NS-critical-d_07-13\|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MACC1 CDC42BPA ANXA2 C6orf132 PTPRF	7.65e-05	198	98	5	a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCell	kidney_cells\|World / Celltypes from Cells and Nuclei per compartment and clinical group	RPL35A RPS4X SELENOH PRDX1 SOD1	7.65e-05	198	98	5	13f74660bc571312355446e78891931b1295d720
ToppCell	NS-moderate\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RPL35A ANXA2 RPS4X AKR1B10 PRDX1	7.65e-05	198	98	5	47dd7f6bc5f2e989104759fd0b0e0b71baa85453
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature2_(2)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RPL35A RPS4X ENPP2 OLFML3 ADAMTS12	7.65e-05	198	98	5	df681a2308bf75f4d3cef05d7418aabc96116880
ToppCell	proximal-mesenchymal-Alveolar_Fibroblast\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ENPP2 OLFML3 ADAMTS12 HMCN1 PTPRS	7.83e-05	199	98	5	7f4840ae6a888380feca722543e5e52783f3e35d
ToppCell	proximal-3-mesenchymal-Alveolar_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ENPP2 OLFML3 ADAMTS12 HMCN1 PTPRS	7.83e-05	199	98	5	301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCell	critical-Epithelial\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MACC1 ANXA2 C6orf132 PTPRF PRDX1	7.83e-05	199	98	5	bbb44e2a52f102a6d891ead6c06d6c07221abd33
ToppCell	wk_08-11-Mesenchymal-Fibroblast-intermediate_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NAALAD2 RPL35A ENPP2 OLFML3 ADAMTS12	7.83e-05	199	98	5	f9e3fb974ba8fe1b6d99892577549ef143df9e08
ToppCell	proximal-mesenchymal-Alveolar_Fibroblast-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ENPP2 OLFML3 ADAMTS12 HMCN1 PTPRS	7.83e-05	199	98	5	9a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature2_(2)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RPL35A RPS4X ENPP2 OLFML3 ADAMTS12	7.83e-05	199	98	5	d946db0e8cc3fbed2d0eb9b4346400138d43219f
ToppCell	NS-critical-d_07-13-Epithelial\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MACC1 ANXA2 C6orf132 PTPRF PRDX1	7.83e-05	199	98	5	b88a81cd2a89f4d27100c96ae4324dcee68daf83
ToppCell	COVID_vent-Lymphocytic-T_cell-CD4+_Naive_T_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	EVL RPL35A RPS4X NKTR SOD1	7.83e-05	199	98	5	885bc902b6e2af0b61e452c4154160cd3f1cf98e
ToppCell	11.5-Distal-Mesenchymal-Mesenchyme_RSPO2+\|Distal / Age, Tissue, Lineage and Cell class	RPL35A RPS4X ENPP2 OLFML3 ADAMTS12	7.83e-05	199	98	5	cea1b30f3e3a9b4ccbc8b57f82352067be1a1d68
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TANC2 CAMSAP3 LDLR PTPRF TGDS	8.02e-05	200	98	5	e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCell	control-Epithelial\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MACC1 ANXA2 C6orf132 PTPRF PRDX1	8.02e-05	200	98	5	f95bbb94e51ac28b1995026c599ec3a34e012916
ToppCell	critical-Myeloid-Monocyte-derived_DC\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RPL35A ANXA2 RPS4X OLFML3 PRDX1	8.02e-05	200	98	5	e2d0e635b70f4bc25e1d374d46e63efbb2e2be0f
ToppCell	cellseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RPL35A RPS4X SELENOH PRDX1 SOD1	8.02e-05	200	98	5	6a3020ced89b1d0864f087ecd03be2b86e6bb210
ToppCell	NS-control-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MACC1 ANXA2 C6orf132 PTPRF PRDX1	8.02e-05	200	98	5	d014959891893b6d3854a471fba1dc50c6625a0a
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal\|5w / Sample Type, Dataset, Time_group, and Cell type.	RPL35A ANXA2 RPS4X SRP54 TGDS	8.02e-05	200	98	5	fc73565f973c70915e7415f30d7295a63e33d712
ToppCell	critical-Epithelial-Secretory-diff\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ANXA2 RPS4X AKR1A1 AKR1B10 PRDX1	8.02e-05	200	98	5	407465404c5818bd2cd9d489bfbf29c3a55429d4
ToppCell	wk_08-11-Mesenchymal-Fibroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NAALAD2 RPL35A ENPP2 OLFML3 ADAMTS12	8.02e-05	200	98	5	482dfbbd8958b64c31568dccbffe3cc9589f876b
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|390C / Donor, Lineage, Cell class and subclass (all cells)	CRYBG2 THUMPD3 APAF1 CDC42BPB	1.06e-04	111	98	4	dfbdeadad321392d359e6fb7112b28b043a4b874
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	RPL35A RPS4X ENPP2 SHC2	2.88e-04	144	98	4	ea174487f8ade90deb33b964a7f7e65062606565
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ENPP1 RFC4 KMT2D AGAP2	3.53e-04	152	98	4	0652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Tnc\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MACC1 NEB ZBBX VWA3B	3.71e-04	154	98	4	0066b2b8cfc74603e97f271ef5efc7ec512110dc
ToppCell	10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-pDC_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MACC1 SIGLEC8 ZDHHC15 PRDX1	3.71e-04	154	98	4	ac539c8ca9e1d48b59bff8026775c2147543f3e2
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	RPL35A RPS4X NKTR	3.97e-04	65	98	3	6e074496433d86c2818e72f18cdbe00eb33333b7
ToppCell	metastatic_Brain-Myeloid_cells-Undetermined\|Myeloid_cells / Location, Cell class and cell subclass	CRYBG2 NLRP7 OLFML3 PRDX1	3.99e-04	157	98	4	6ce7f2ea613e7f8e771860e8c0512274e4f54369
ToppCell	ICU-NoSEP-Lymphocyte-T_NK-CD4_TEM\|ICU-NoSEP / Disease, Lineage and Cell Type	EVL RPL35A RPS4X GJA3	4.09e-04	158	98	4	8616b308d5c1a1042b23a9aaca971029ba732eb8
ToppCell	NS-critical-d_07-13-Epithelial-Basal\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RPL35A ANXA2 RPS4X PRDX1	4.29e-04	160	98	4	f538ce75500773b5dda53fec4cde2f557d816f4e
ToppCell	ICU-NoSEP-Lymphocyte-T_NK-CD8_TCM\|ICU-NoSEP / Disease, Lineage and Cell Type	RPL35A RPS4X VWDE HRH1	4.29e-04	160	98	4	a1bf6ed365cbc1ddb57c132a42dbe6485d45f544
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDC42BPA ACAT2 FAN1 CAMSAP2	4.60e-04	163	98	4	d2fcd6f561748f7d29a051c504f016952ba32d0f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANXA2 ANXA2P2 ADAMTS12 ALK	4.82e-04	165	98	4	2d01ae5d05fe55f6bebd53a5801c4c1f1544515c
ToppCell	LV-11._Adipocyte\|World / Chamber and Cluster_Paper	ENPP2 ADAMTS12 PTPRF AGMO	4.93e-04	166	98	4	7e5852891714465c6228c9f955fd511ec79d0e02
ToppCell	facs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLRP2 VWDE HMCN1 PTPRS	5.04e-04	167	98	4	78909f685ccd1321064eb0887caf9263e0e54879
ToppCell	droplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAMSAP3 PTPRF PTPRS HRH1	5.27e-04	169	98	4	7962165cab84af73d20b56eb70b1ed87c94025ef
ToppCell	IIF-Lymphocyte-T_NK-Treg\|IIF / Disease, Lineage and Cell Type	EVL RPL35A RPS4X SOD1	5.27e-04	169	98	4	aac6ff89e0b3bc1f644e6cc6a696360659b254b5
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVL RPL35A MYCBP2 RPS4X	5.39e-04	170	98	4	90f7640f04672c800cb28aea50004b1bb0565e8a
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MACC1 CAMSAP3 PTPRF LRP2	5.39e-04	170	98	4	4ce81608111b9ee7cb974dad2c182f38db3dcd79
ToppCell	mild-Myeloid-Eosinophils\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	LANCL3 SIGLEC8 YES1 SLFN13	5.51e-04	171	98	4	5c8198182495bda7a826e9d80aa467f4eb1094ec
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Deuterosomal\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ZBBX ADGB DNAH17 VWA3B	5.63e-04	172	98	4	08ad76412c9cc3504141797b44b88478ced87476
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42BPB ZDHHC15 PTPRF HRH1	5.63e-04	172	98	4	7fb31ccbcd0204c3612986a6bc20d57ed6825e9c
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LANCL3 RFC4 PPP1R26 KNL1	5.63e-04	172	98	4	7c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42BPB ZDHHC15 PTPRF HRH1	5.63e-04	172	98	4	2a4614b3d25e8c6b095e6992d8ca35371dcdb5e1
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANXA2 ANXA2P2 CNTN5 ALK	5.76e-04	173	98	4	61907116a1460bc157ba73b5edd108db7dd5de4b
ToppCell	facs-Marrow-T_cells-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPST1 MACC1 ENPP1 ALDH1L2	5.76e-04	173	98	4	e0cf99ddbe6e9eab05d7bf89e9aa124850c6a807
ToppCell	facs-Marrow-T_cells-18m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPST1 MACC1 ENPP1 ALDH1L2	5.88e-04	174	98	4	3b1ee39e85e5f0d6b17fb3051dbfae66cb2be6ee
ToppCell	10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages\|bone_marrow / Manually curated celltypes from each tissue	ENPP2 OLFML3 PPP1R26 HRH1	5.88e-04	174	98	4	0746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPST1 ENPP1 PKD2L1 ALDH1L2	5.88e-04	174	98	4	cdfc50e5383c8670ce5109736aff36406f46c03d
ToppCell	facs-Marrow-T_cells-18m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPST1 MACC1 ENPP1 ALDH1L2	6.01e-04	175	98	4	4be01bf30331162f1998216fb2871a4e626dc440
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-stromal_related\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NLRP7 NLRP2 ZBBX BRDT	6.01e-04	175	98	4	2fbffcb843f364645b99d1211698d96092abc5ef
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-stromal_related-Germ\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NLRP7 NLRP2 ZBBX BRDT	6.01e-04	175	98	4	d0d5ae2a9357aa183ab720c891d86b80c9822930
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CRYBG2 THUMPD3 APAF1 CDC42BPB	6.01e-04	175	98	4	334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-31\|World / Primary Cells by Cluster	RPL35A RPS4X ZFP37 PTPRS	6.01e-04	175	98	4	491508bf9e8a09b057d5711cc23dd91324e6a806
ToppCell	droplet-Lung-LUNG-30m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MACC1 C6orf132 PTPRF LRP2	6.14e-04	176	98	4	5201f003192c033655ba47f0faf8c47a96eae03d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANXA2 ANXA2P2 CNTN5 ALK	6.14e-04	176	98	4	4843af68f013732c28a8b8edad30d5fa0f2b084b
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ENPP1 ADAMTS12 PPP1R26 BARX1	6.27e-04	177	98	4	6b4fe717928814dafcd13090b1c90ea973938c6d
Drug	Famprofazone [22881-35-2]; Up 200; 10.6uM; HL60; HT_HG-U133A	CRYBG2 CDC42BPA ENPP1 ENPP2 PTPRF DNAH17 LRP2 BARX1 AGAP2	1.92e-07	196	99	9	2174_UP
Drug	lithium sulfate monohydrate	AKR1A1 AKR1B10 TGDS DHODH	2.32e-06	22	99	4	CID000165815
Drug	NSC406942	ANXA2 ENPP1 ENPP2 SRP54 AKR1A1 YES1 GJA3 AKR1B10 HPS6 DHODH MCRS1 IFT122	6.30e-06	565	99	12	CID000001115
Disease	azoospermia (implicated_via_orthology)	CDC42BPA CDC42BPB PTPRF PTPRS	1.67e-06	27	95	4	DOID:14227 (implicated_via_orthology)
Disease	peroxiredoxin-1 measurement	AKR1A1 PRDX1	3.07e-05	3	95	2	EFO_0020629
Disease	gestational age	PNMA6F MOV10L1 VWA3B TET3 ALK	8.60e-05	138	95	5	EFO_0005112
Disease	margarate 17:0 measurement	PKD2L1 ALK	3.64e-04	9	95	2	EFO_0021066
Disease	cerebral cavernous malformation (implicated_via_orthology)	CDC42BPA CDC42BPB	5.54e-04	11	95	2	DOID:0060669 (implicated_via_orthology)
Disease	renal cell carcinoma (biomarker_via_orthology)	ANXA2 ANXA2P2	9.10e-04	14	95	2	DOID:4450 (biomarker_via_orthology)
Disease	Atherosclerosis	LDLR HRH1 SOD1	9.22e-04	59	95	3	C0004153
Disease	Atherogenesis	LDLR HRH1 SOD1	9.22e-04	59	95	3	C1563937
Disease	serum metabolite measurement	TANC2 NAALAD2 CDC42BPA PKD2L1 LDLR OLFML3 ALDH1L2 LINC02902 DNAH17 ALK	9.37e-04	945	95	10	EFO_0005653
Disease	response to radiation, Urinary retention	PTPRS AGMO	1.35e-03	17	95	2	GO_0009314, HP_0000016
Disease	Eye Abnormalities	APAF1 IFT122	1.35e-03	17	95	2	C0015393
Disease	hypothyroidism (biomarker_via_orthology)	ANXA2 ANXA2P2 SOD1	2.22e-03	80	95	3	DOID:1459 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
IKPVNVGALSKWVGK	TPST1	291	O60507
VGALSKWVGKIPPDV	TPST1	296	O60507
IQQKLSKLKGEPGWV	APAF1	136	O14727
WKSLGKPVKPSGVMK	BRDT	806	Q58F21
GSTEQKKGKFPLWPE	ADGB	36	Q8N7X0
VVSWILKGKPPGRLD	AGMO	56	Q6ZNB7
DGTPVFKLPKWRVKG	ALDH1L2	71	Q3SY69
VGLGTWKSPLGKVKE	AKR1B10	16	O60218
SWPESEGKPRVKGSK	AGAP2	211	Q99490
VGWGTPKVTRLPKLE	ARL13B	381	Q3SXY8
AGVKRKGTDVPKWIS	ANXA2	201	P07355
AGVKRKGTDVPKWIS	ANXA2P2	201	A6NMY6
HLWQGKKPTTPKKGG	CAMSAP3	1231	Q9P1Y5
CITVGKKPESIPGGW	ADAMTS12	531	P58397
QGSPKPTISWKKGDR	CNTN5	506	O94779
SGEPGVPTKKTWFDK	RBM26	496	Q5T8P6
SGLEGPLTKKPWLGK	RBM27	566	Q9P2N5
KILKRFGGPAGLWTK	OLFML3	146	Q9NRN5
KVKIERPGGSLSPIW	IFT122	166	Q9HBG6
TSLLGWEKLPKKGFP	MOV10L1	1001	Q9BXT6
VWGGGKSTPQKLDVI	NEK9	351	Q8TD19
KWKKIVLQGGGLESP	BARX1	196	Q9HBU1
WIEGNPKLSFLKPGI	DDX58	646	O95786
CGNFLGGKWIPKEKP	HMGXB3	336	Q12766
KGGPWKVISLPQALD	PNMA6F	81	A0A0J9YX94
KKWVPIKPGQQGFSR	EVL	21	Q9UI08
LTWQKGLLKKGPGIC	LANCL3	326	Q6ZV70
VKIWGRKSVGGPKID	KNL1	871	Q8NG31
HTWGGLLPVISKLKK	ENPP1	226	P22413
GDWEKKKPVPVLLGS	NLRP2	306	Q9NX02
LVKTKLGWPAGVTLD	LRP2	551	P98164
GQGKKEKTLVVNPWL	LRP2	4301	P98164
PGEGLGIFSKTWIKA	PRDM12	96	Q9H4Q4
HVKVPKPTGVKKGWQ	CDC42BPB	1101	Q9Y5S2
GRKTNIWTIIPKKLG	OVOS2	841	Q6IE36
TKGGKIPNPIRSWKD	DDX23	381	Q9BUQ8
IPLGSLGWKTVKQPV	NDUFA9	226	Q16795
VKTKRGPLGPNWKKE	PITPNB	166	P48739
GNPKPSVIWSKKGEL	HMCN1	1006	Q96RW7
KGTPKPTIKWLHNGR	HMCN1	1291	Q96RW7
KGDLWGPGLSPKEVK	HMCN1	2671	Q96RW7
NGIPTPLIQWLKDGK	HMCN1	3271	Q96RW7
PLIQWLKDGKPIASG	HMCN1	3276	Q96RW7
GWKPGSDTIKPDVQK	PRDX1	176	Q06830
ATGDPKPRVTWNKKG	PTPRS	56	Q13332
PPGGVTKWKSDVALN	C6orf132	251	Q5T0Z8
SPKAWLGPGTAKLLK	CCDC71	411	Q8IV32
IKWVDGGKPLLKIST	DOCK9	801	Q9BZ29
KKGKLQKEAGTPPLW	ADAR	181	P55265
LTAPGGKIPKDKSWK	DNAH17	3171	Q9UFH2
LPLEGWSPALKTQGK	CRYBG2	966	Q8N1P7
AWILIVSCKKGKGTP	LINC02902	131	Q6ZTY9
EGKNIIIWLPTGAGK	DHX58	16	Q96C10
VINKVFKDWKPGGVI	DHX58	596	Q96C10
KKGGKNISPVVFQLW	MACC1	406	Q6ZN28
EGPAWKISRKQGVIK	MCRS1	381	Q96EZ8
GQIKGLTSWPGKLVR	MBD5	1391	Q9P267
PWEVLKRKPKDAGGG	HRH1	256	P35367
TVKGKGCPKPIKSWV	DDX46	361	Q7L014
GWKKLKQGVTSRLGP	GJA3	226	Q9Y6H8
PDVWKKVLGGITAGK	HPS6	541	Q86YV9
EAKWVPGVPGNTKII	SLFN13	766	Q68D06
PGGQKSPSKWFWKLV	CAMSAP2	211	Q08AD1
GGQPLWITATKQGVK	ENPP2	256	Q13822
ATGEPKPRITWMKKG	PTPRF	56	P10586
TWGKNKPGIGAVILK	FAN1	511	Q9Y2M0
GAKQNTGVWLVKVPK	GTF2F2	11	P13984
GGKPNKTRVIWGKVT	RPL35A	61	P18077
AGSSGENKKAKPVPW	RFC4	26	P35249
LVDPGVKAWTPTKGK	SRP54	86	P61011
LIDKKWKPLQGVGNL	NKTR	1221	P30414
TALTFWGPPVVGKVK	DHODH	356	Q02127
GPLTESWKDGNPLKK	SIGLEC8	416	Q9NYZ4
VTLLKKGAKIGPATW	TANC2	1216	Q9HCD6
GDWEKKKPVPVLLGS	NLRP7	271	Q8WX94
IKQGGPSAGKWVELP	MYCBP2	561	O75592
LAKKDGGPWPTRKAQ	PPP1R26	1136	Q5T8A7
FVIGKGNKPWISLPR	RPS4X	226	P62701
IPKPAGVKKGWQRAL	CDC42BPA	1091	Q5VT25
SNGPVKVWGSIKGLT	SOD1	26	P00441
NWPKQKAVTGLVGIG	ERVK-9	821	P63128
SEGPLKGIQIWKVPA	ALK	716	Q9UM73
LIGLGTWKSEPGQVK	AKR1A1	16	P14550
IWKKLFVPLKAGGAP	C11orf91	41	Q3C1V1
GLGWRPKVPWKEGIK	TGDS	311	O95455
SGVLVLDPTSGPKWK	TOP3B	731	O95985
LVGGKPTGKWQLKVS	VWDE	1006	Q8N2E2
KNWPKQKAVTGLVGI	ERVK-9	41	P63127
KNWPKQKAVTGLVGI	ERVK-24	41	P63129
KPKKPLTLSLHGWTG	TOR1A	91	O14656
GPIPAIKQAVTKAGW	ACAT2	296	Q9BWD1
PGVRGSWKKKAPNKA	SHC2	191	P98077
KNWPKQKAVTGLVGI	HERVK_113	41	P63121
KPAVSGKQGNVLPLW	PRPF38B	36	Q5VTL8
AELWTGIKKGPPRKL	SELENOH	91	Q8IZQ5
KNWPKQKAVTGLVGI	ERVK-7	41	P63131
KWSSKPGIPAAEVGI	VCL	911	P18206
KNWPKQKAVTGLVGI	ERVK-6	41	Q9Y6I0
KNWPKQKAVTGLVGV	ERVK-25	41	P63125
GKKRKWGGTVVAEPQ	TET3	1741	O43151
KNWPKQKAVTGLVGI	ERVK-10	41	P10265
KGWLAPSPGVKEQAI	PKD2L1	741	Q9P0L9
QLSPEKSEIWGPGLK	POGLUT2	26	Q6UW63
QIKEGKPSWGLPIDA	THUMPD3	371	Q9BV44
KNWPKQKTVTGLVGI	ERVK-18	41	P63123
MTWNSRKLKGKLPPG	VWA3B	316	Q502W6
KNWPKQKAVIGLVGI	ERVK-8	41	P63122
QKWIVKPPASARGIG	TTLL4	716	Q14679
ISKLEKGEAPWLGKG	ZFP37	81	Q9Y6Q3
KNWPKQKAVTGLVGI	ERVK-21	41	P63119
FVVLPWGKPGNSVKL	ZBBX	6	A8MT70
DKKKFWLIPIGSSPG	ZDHHC15	276	Q96MV8
KNWPKQKAVTGLVGI	HERV-K104	41	P63124
WNGTTKVAIKTLKPG	YES1	296	P07947
KNWPKQKAVTGLVGI	ERVK-19	41	P63120
PGKLPVTTWEKGKGS	KMT2D	4766	O14686
WGTPAKIKKGGLNGV	LDLR	536	P01130
GIAPPDKSWKGALNV	NAALAD2	301	Q9Y3Q0
KGIGWIPIGSLDVEK	NEB	1201	P20929