Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessmicrotubule-based process

DRC7 IFT172 CNTRL EML2 STARD7 DYSF EML3 CEP350 IGBP1 DNAH12 DST KIF2A CYB5D1 CROCC HSPB1 CFAP46 DNAH11 WDR72

6.97e-06105810618GO:0007017
GeneOntologyBiologicalProcessmicrotubule-based movement

DRC7 IFT172 STARD7 IGBP1 DNAH12 DST KIF2A CYB5D1 HSPB1 CFAP46 DNAH11

4.68e-0549310611GO:0007018
DomainHELP

EML2 EML3 EML5

3.71e-0661083PF03451
DomainHELP

EML2 EML3 EML5

3.71e-0661083IPR005108
DomainActinin_actin-bd_CS

SYNE1 SPTBN1 SPTBN2 DST

8.60e-06231084IPR001589
DomainSpectrin

SYNE1 SPTBN1 SPTBN2 DST

8.60e-06231084PF00435
DomainACTININ_2

SYNE1 SPTBN1 SPTBN2 DST

8.60e-06231084PS00020
DomainACTININ_1

SYNE1 SPTBN1 SPTBN2 DST

8.60e-06231084PS00019
DomainQuinoprotein_ADH-like_supfam

NWD1 EML2 EML3 EML5 WDR72

1.36e-05531085IPR011047
DomainWD40

NWD1 IFT172 WDR81 EML2 EML3 PPP2R2A EML5 WDR97 WDR72

1.95e-052591089PF00400
DomainSpectrin_repeat

SYNE1 SPTBN1 SPTBN2 DST

2.25e-05291084IPR002017
DomainWD40

NWD1 IFT172 WDR81 EML2 EML3 PPP2R2A EML5 WDR97 WDR72

2.56e-052681089SM00320
DomainWD40_repeat

NWD1 IFT172 WDR81 EML2 EML3 PPP2R2A EML5 WDR97 WDR72

2.87e-052721089IPR001680
DomainSpectrin/alpha-actinin

SYNE1 SPTBN1 SPTBN2 DST

3.36e-05321084IPR018159
DomainSPEC

SYNE1 SPTBN1 SPTBN2 DST

3.36e-05321084SM00150
DomainWD_REPEATS_1

NWD1 IFT172 WDR81 EML2 EML3 PPP2R2A EML5 WDR97 WDR72

3.41e-052781089PS00678
DomainWD_REPEATS_2

NWD1 IFT172 WDR81 EML2 EML3 PPP2R2A EML5 WDR97 WDR72

3.50e-052791089PS50082
DomainWD_REPEATS_REGION

NWD1 IFT172 WDR81 EML2 EML3 PPP2R2A EML5 WDR97 WDR72

3.50e-052791089PS50294
DomainCH

SYNE1 SPTBN1 SPTBN2 LRCH1 DST

3.69e-05651085SM00033
DomainCH

SYNE1 SPTBN1 SPTBN2 LRCH1 DST

5.29e-05701085PF00307
Domain-

SYNE1 SPTBN1 SPTBN2 LRCH1 DST

5.66e-057110851.10.418.10
DomainWD40_repeat_dom

NWD1 IFT172 WDR81 EML2 EML3 PPP2R2A EML5 WDR97 WDR72

5.69e-052971089IPR017986
DomainCH

SYNE1 SPTBN1 SPTBN2 LRCH1 DST

6.47e-05731085PS50021
DomainCH-domain

SYNE1 SPTBN1 SPTBN2 LRCH1 DST

7.37e-05751085IPR001715
Domain-

NWD1 IFT172 WDR81 EML2 EML3 PPP2R2A EML5 WDR97 WDR72

1.36e-0433310892.130.10.10
DomainWD40/YVTN_repeat-like_dom

NWD1 IFT172 WDR81 EML2 EML3 PPP2R2A EML5 WDR97 WDR72

1.42e-043351089IPR015943
DomainSpectrin_bsu

SPTBN1 SPTBN2

1.97e-0441082IPR016343
DomainPH_dom-spectrin-type

SPTBN1 SPTBN2

1.16e-0391082IPR001605
DomainQuinoprot_gluc/sorb_DH

EML2 EML5

2.11e-03121082IPR011041
DomainDynein_heavy_chain_D4_dom

DNAH12 DNAH11

2.88e-03141082IPR024317
DomainDynein_heavy_dom-2

DNAH12 DNAH11

2.88e-03141082IPR013602
DomainDHC_N2

DNAH12 DNAH11

2.88e-03141082PF08393
DomainAAA_8

DNAH12 DNAH11

2.88e-03141082PF12780
DomainATPase_dyneun-rel_AAA

DNAH12 DNAH11

2.88e-03141082IPR011704
DomainAAA_5

DNAH12 DNAH11

2.88e-03141082PF07728
DomainDHC_fam

DNAH12 DNAH11

3.31e-03151082IPR026983
DomainDynein_heavy_dom

DNAH12 DNAH11

3.31e-03151082IPR004273
DomainDynein_heavy

DNAH12 DNAH11

3.31e-03151082PF03028
DomainCadherin

RET CELSR3 DCHS1 PCDH7

4.20e-031131084PF00028
DomainCADHERIN_2

RET CELSR3 DCHS1 PCDH7

4.33e-031141084PS50268
Domain-

RET CELSR3 DCHS1 PCDH7

4.33e-0311410842.60.40.60
DomainCA

RET CELSR3 DCHS1 PCDH7

4.47e-031151084SM00112
DomainCadherin-like

RET CELSR3 DCHS1 PCDH7

4.61e-031161084IPR015919
DomainCadherin

RET CELSR3 DCHS1 PCDH7

4.90e-031181084IPR002126
DomainApc4_WD40_dom

NWD1 EML5

5.88e-03201082IPR024977
DomainANAPC4_WD40

NWD1 EML5

5.88e-03201082PF12894
Pubmed

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

STK38 LRCH1 PPP2R2A KIF2A SLFN11 NCKAP1L

4.45e-06129114623022380
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SPTBN1 SLC1A5 CEP350 PJA2 DST TIAM1 TRIM9 MAP3K9 NHS GAN KIF2A PCDH7 GOLGB1

5.21e-068611141336931259
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TBRG4 PIEZO1 LRCH1 PPP2R2A DST CELSR3 USP38 TRIM9 RIMS2 CRAMP1

1.01e-055291141014621295
Pubmed

Iron-inhibited autophagy via transcription factor ZFP27 in Parkinson's disease.

ZNF585A ZNF585B

1.07e-052114237668106
Pubmed

Functional TRPV6 channels are crucial for transepithelial Ca2+ absorption.

EPHB6 TRPV6

1.07e-052114222878123
Pubmed

Activation of the calcium sensing receptor attenuates TRPV6-dependent intestinal calcium absorption.

EPHB6 TRPV6

1.07e-052114231013259
Pubmed

Calcium channel TRPV6 is involved in murine maternal-fetal calcium transport.

EPHB6 TRPV6

1.07e-052114218348695
Pubmed

Trpv6 mediates intestinal calcium absorption during calcium restriction and contributes to bone homeostasis.

EPHB6 TRPV6

1.07e-052114220399919
Pubmed

TRPV6 is not required for 1alpha,25-dihydroxyvitamin D3-induced intestinal calcium absorption in vivo.

EPHB6 TRPV6

1.07e-052114219073913
Pubmed

Eml5, a novel WD40 domain protein expressed in rat brain.

EML3 EML5

1.07e-052114215225882
Pubmed

Variants That Affect Function of Calcium Channel TRPV6 Are Associated With Early-Onset Chronic Pancreatitis.

EPHB6 TRPV6

1.07e-052114231930989
Pubmed

Caspase-3/7-mediated Cleavage of β2-spectrin is Required for Acetaminophen-induced Liver Damage.

SPTBN1 SPTBN2

1.07e-052114226884715
Pubmed

The polymorphism of SREBF1 gene rs11868035 G/A is associated with susceptibility to Parkinson's disease in a Chinese population.

SREBF1 USP25

1.07e-052114230231795
Pubmed

Marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel gene.

EPHB6 TRPV6

1.07e-052114217129178
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

GAK PRXL2B SYNE1 SPTBN1 SPTBN2 DARS1 ZNFX1 CADM2 PPP2R2A DST TRIM9 OSBPL9 KIF2A CROCC HSPB1 DNAH11

1.79e-0514311141637142655
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

DRC7 GAK SPTBN1 STK38 CHML IGBP1 DST OSBPL9 PRMT7 CROCC

1.86e-055681141037774976
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

EPHB6 LONRF1 IFT172 SYNE1 SPTBN1 SPTBN2 USP25 DARS1 ZNFX1 CEP350 DST CELSR3 TIAM1 UBE3A TRIM9

2.04e-0512851141535914814
Pubmed

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

GAK SREBF1 USP25

2.70e-0518114321738487
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

HSPBAP1 SPTBN2 ARHGAP9 CSMD2 CHML KY DST TRIM9 MAP3K9 ANKRD18A RGL4

3.16e-057361141129676528
Pubmed

TRPV6 and Cav1.3 Mediate Distal Small Intestine Calcium Absorption Before Weaning.

EPHB6 TRPV6

3.19e-053114231398491
Pubmed

Excision of Trpv6 gene leads to severe defects in epididymal Ca2+ absorption and male fertility much like single D541A pore mutation.

EPHB6 TRPV6

3.19e-053114222427671
Pubmed

Genome-wide identification of mouse congenital heart disease loci.

IFT172 DNAH11

3.19e-053114220511334
Pubmed

Male fertility depends on Ca²+ absorption by TRPV6 in epididymal epithelia.

EPHB6 TRPV6

3.19e-053114221540454
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

SYNE1 STK38 DST CELSR3 GAN CROCC

3.67e-05187114626460568
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

IFT172 SYNE1 DST

3.75e-0520114321689717
Pubmed

Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.

CSMD2 FHAD1 USP38 PRMT7

5.62e-0563114411572484
Pubmed

Tumor progression in the LPB-Tag transgenic model of prostate cancer is altered by vitamin D receptor and serum testosterone status.

EPHB6 TRPV6

6.36e-054114220347977
Pubmed

Apparent structural differences at the tetramerization region of erythroid and nonerythroid beta spectrin as discriminated by phage displayed scFvs.

SPTBN1 SPTBN2

6.36e-054114221412925
Pubmed

Active intestinal calcium transport in the absence of transient receptor potential vanilloid type 6 and calbindin-D9k.

EPHB6 TRPV6

6.36e-054114218325990
Pubmed

The Celsr3-Kif2a axis directs neuronal migration in the postnatal brain.

CELSR3 KIF2A

6.36e-054114234582949
Pubmed

CRIS-a novel cAMP-binding protein controlling spermiogenesis and the development of flagellar bending.

IFT172 KIF2A

6.36e-054114224339785
Pubmed

Maternal Epidermal Growth Factor Promotes Neonatal Claudin-2 Dependent Increases in Small Intestinal Calcium Permeability.

EPHB6 TRPV6

6.36e-054114237575484
Pubmed

Loss of β2-spectrin prevents cardiomyocyte differentiation and heart development.

SPTBN1 SPTBN2

6.36e-054114224064296
Pubmed

Multiple Isoforms of Nesprin1 Are Integral Components of Ciliary Rootlets.

SYNE1 CROCC

6.36e-054114228625779
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ZNF585A LONRF1 PIEZO1 SREBF1 EML2 DYSF SLC1A5 EML3 DST CELSR3 IL17RE POLL CRAMP1

7.00e-0511051141335748872
Pubmed

Thalamocortical control of cell-type specificity drives circuits for processing whisker-related information in mouse barrel cortex.

CELSR3 RIMS2

1.06e-045114237770450
Pubmed

TGF-β/β2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome.

SPTBN1 SPTBN2

1.06e-045114226784546
Pubmed

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.

SYNE1 STK38 CHML SLC1A5 OSBPL9 CROCC GOLGB1

1.33e-04339114737232246
Pubmed

ST3GAL1 and βII-spectrin pathways control CAR T cell migration to target tumors.

SPTBN1 SPTBN2

1.58e-046114237069398
Pubmed

Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CNTRL WDR81 DYSF ALS2CL

1.81e-0485114415449545
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

SYNE1 SPTBN1 CNTRL SREBF1 STK38 STT3A DCHS1 RIMS2 HSPB1 GOLGB1

1.94e-047541141035906200
Pubmed

Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.

USP25 STARD7 DARS1 IGBP1 TIAM1 GOLGB1

2.10e-04257114630945288
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH12 DNAH11

2.21e-04711429256245
Pubmed

Microtubule association of EML proteins and the EML4-ALK variant 3 oncoprotein require an N-terminal trimerization domain.

EML2 EML3

2.21e-047114225740311
Pubmed

Specific and ubiquitous expression of different Zn finger protein genes in the mouse.

ZNF585A ZNF585B

2.21e-04711423143103
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

EPHB6 SREBF1 STK38 RET MAP3K9 GAN SLFN11

2.34e-04372114722939624
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

CNTRL SENP3 SLC1A5 CEP350 IGBP1 DST OSBPL9 PCDH7 HSPB1 GOLGB1

2.47e-047771141035844135
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

SPTBN1 SENP3 SPTBN2 DARS1 LRCH1 STT3A PPP2R2A GTF2H4 DST OASL GAN KIF2A HSPB1

2.49e-0412571141336526897
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

TBRG4 SENP3 ZNFX1 CSMD2 CEP350 DNAH12 UBE3A SLFN11 DNAH11

2.61e-04638114931182584
Pubmed

Tissue expression patterns identify mouse cilia genes.

DRC7 IFT172 CYB5D1 CROCC

2.88e-0496114417971504
Pubmed

Expression of testicular germ cell genes identified by differential display analysis.

ANKRD18B ANKRD18A

2.94e-048114212634303
Pubmed

An N-ethyl-N-nitrosourea mutagenesis screen for epigenetic mutations in the mouse.

HSPB1 DNMT3L

2.94e-048114212930754
Pubmed

3D-structured illumination microscopy provides novel insight into architecture of human centrosomes.

CNTRL KIF2A

2.94e-048114223213374
Pubmed

Self-stabilizing regulation of deubiquitinating enzymes in an enzymatic activity-dependent manner.

USP25 USP38

2.94e-048114233864866
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SYNE1 SPTBN1 SENP3 SPTBN2 WDR81 ZNFX1 DST UBE3A DCHS1 KIF2A GOLGB1

3.33e-049631141128671696
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

SYNE1 SPTBN1 SPTBN2 MAP3K9 RIMS2 PCDH7

3.39e-04281114628706196
Pubmed

An integrated workflow for charting the human interaction proteome: insights into the PP2A system.

WDR81 CEP350 PPP2R2A IGBP1

4.06e-04105114419156129
Pubmed

Cell organization, growth, and neural and cardiac development require αII-spectrin.

SPTBN1 SPTBN2

4.71e-0410114222159418
Pubmed

The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation.

PRMT7 DNMT3L

4.71e-0410114217048991
Pubmed

BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A.

GAK IFT172 PRXL2B SENP3 STK38 CHML DYSF

4.77e-04419114733001583
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

SPTBN1 SPTBN2 STK38 SLC1A5 IGBP1 DST NHS GOLGB1

5.64e-04565114825468996
Pubmed

Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin.

SPTBN1 SPTBN2

5.75e-0411114217607528
Pubmed

Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy.

CSMD2 ZSCAN20

5.75e-0411114216429158
Pubmed

Studies of nematode TFIIE function reveal a link between Ser-5 phosphorylation of RNA polymerase II and the transition from transcription initiation to elongation.

GTF2F1 GTF2H4

5.75e-0411114211113176
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

TBRG4 PLCXD1 SYNE1 WDR81 STT3A OASL OSBPL9 HSPB1 WDR72

6.18e-04719114935337019
Pubmed

A "double adaptor" method for improved shotgun library construction.

B3GNTL1 FBXL5 CEP350 MRPL4 CLCN4 TIAM1 RIMS2 HSPB1

6.25e-0457411488619474
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

PIEZO1 SENP3 CEP350 KIF2A HSPB1

6.59e-04210114516565220
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

SYNE1 SPTBN1 DST ZNF544

6.71e-04120114431413325
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

SPTBN1 SPTBN2 SLC1A5 CEP350 PPP2R2A GTF2F1 IGBP1 TIAM1 NHS SLFN11 PCDH7

6.79e-0410491141127880917
Pubmed

Planar cell polarity genes control the connectivity of enteric neurons.

RET CELSR3

6.88e-0412114223478408
Pubmed

BRCA1 is a component of the RNA polymerase II holoenzyme.

GTF2F1 GTF2H4

6.88e-041211429159119
Pubmed

Proximity labeling reveals dynamic changes in the SQSTM1 protein network.

TBRG4 PJA2 IGBP1 TRIM9 CROCC HSPB1

6.94e-04322114639098523
Pubmed

Claudin-4 localization in epithelial ovarian cancer.

SPTBN2 SLC1A5 GOLGB1

7.53e-0454114336237976
Pubmed

alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.

SPTBN1 SPTBN2

8.11e-0413114218796539
Pubmed

Formation of the Mouse Internal Capsule and Cerebral Peduncle: A Pioneering Role for Striatonigral Axons as Revealed in Isl1 Conditional Mutants.

CADM2 CNTN5

8.11e-0413114235273083
Pubmed

NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.

SYNE1 SPTBN1 SPTBN2 SLC1A5 OASL OSBPL9

8.26e-04333114632665550
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PRUNE2 SYNE1 LRCH1 DST TRIM9

8.98e-04225114512168954
Pubmed

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.

LONRF1 SPTBN1 IGBP1 OSBPL9 HSPB1

8.98e-04225114525277244
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

SPTBN2 ZNFX1 DST CELSR3

9.05e-04130114412421765
Pubmed

The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells.

FBXO15 DNMT3L

9.45e-0414114212787504
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH12 DNAH11

9.45e-041411429373155
Pubmed

Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages.

FBXO15 DNMT3L

9.45e-0414114221056461
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

STK38 LRCH1 SLC1A5 PPP2R2A DST OSBPL9 PRMT7

9.59e-04472114738943005
Pubmed

A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.

SYNE1 DST GOLGB1

1.02e-0360114320682791
Pubmed

E3 Ligase Trim21 Ubiquitylates and Stabilizes Keratin 17 to Induce STAT3 Activation in Psoriasis.

SPTBN2 DST GAN HSPB1

1.04e-03135114429859926
Pubmed

A human MAP kinase interactome.

SYNE1 SPTBN1 CNTRL SPTBN2 CEP350 DST GOLGB1

1.13e-03486114720936779
Pubmed

DDX39B facilitates the malignant progression of hepatocellular carcinoma via activation of SREBP1-mediated de novo lipid synthesis.

SPTBN1 SREBF1 GAN

1.18e-0363114337052853
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PRUNE2 B3GNTL1 PLCXD1 STT3A PPP2R2A ZNF544 CBFA2T2 OSBPL9 CYB5D1 PRORP CROCC CRAMP1 GOLGB1

1.21e-0314891141328611215
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

GAK SPTBN1 DARS1 DST UBE3A GOLGB1

1.23e-03360114633111431
Pubmed

Near-atomic resolution visualization of human transcription promoter opening.

GTF2F1 GTF2H4

1.24e-0316114227193682
Pubmed

Gene expression in the developing mouse retina by EST sequencing and microarray analysis.

DST ZFHX4 NHS KCTD18

1.26e-03142114411812828
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

NWD1 SPTBN1 SPTBN2 DYSF DNAH12 GAN KIF2A

1.29e-03497114736774506
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

CNTRL CEP350 KIF2A CROCC

1.39e-03146114421399614
Pubmed

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.

CELSR3 DCHS1 PCDH7

1.41e-0367114321875946
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

SYNE1 SPTBN1 DST TRIM9

1.57e-03151114417043677
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

SPTBN1 SPTBN2

1.57e-0318114212119179
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

SYNE1 ZNFX1 EML5 DNAH11

1.61e-03152114434299191
Pubmed

Global proteomics of Ubqln2-based murine models of ALS.

SPTBN1 PJA2 IGBP1 DST UBE3A

1.73e-03261114533277362
Pubmed

PELI1 Selectively Targets Kinase-Active RIP3 for Ubiquitylation-Dependent Proteasomal Degradation.

HSPBAP1 ZSCAN20

1.76e-0319114229883609
Pubmed

Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

GTF2F1 HSPB1

1.95e-0320114216548883
GeneFamilyWD repeat domain containing

NWD1 IFT172 WDR81 EML2 EML3 PPP2R2A EML5 WDR97 WDR72

3.17e-06262839362
GeneFamilyEF-hand domain containing|Spectrins

SPTBN1 SPTBN2

4.31e-0478321113
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SPTBN1 SPTBN2 ARHGAP9 TIAM1 OSBPL9

2.59e-03206835682
GeneFamilyDyneins, axonemal

DNAH12 DNAH11

2.71e-0317832536
GeneFamilyCadherin related

RET DCHS1

2.71e-031783224
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

IFT172 SYNE1 ANKRD18B FHAD1 DNAH12 ANKRD18A CCDC191 CFAP46 DNAH11

2.45e-0920011496a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DRC7 FHAD1 KY DNAH12 WDR97 TRIM9 CFAP46 DNAH11

2.06e-0817911485e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 ANKRD18B FHAD1 DNAH12 ANKRD18A CCDC191 CFAP46 DNAH11

3.85e-0819411484a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NWD1 IFT172 SYNE1 FHAD1 DNAH12 CROCC CFAP46 DNAH11

4.34e-08197114891637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NWD1 IFT172 SYNE1 FHAD1 DNAH12 CROCC CFAP46 DNAH11

4.34e-08197114822c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NWD1 IFT172 SYNE1 FHAD1 DNAH12 CROCC CFAP46 DNAH11

4.34e-0819711483bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NWD1 IFT172 SYNE1 FHAD1 DNAH12 CROCC CFAP46 DNAH11

4.34e-08197114887db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NWD1 FHAD1 DNAH12 ANKRD18A CROCC CFAP46 DNAH11

2.73e-07169114714aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DRC7 NWD1 FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

5.04e-0718511473e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DRC7 NWD1 FHAD1 DNAH12 CROCC CFAP46 DNAH11

5.22e-07186114785787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FHAD1 DNAH12 CNTN5 ANKRD18A CCDC191 CFAP46 DNAH11

6.46e-0719211471b6cac8156e608061e1405e36e18d185b6fa8f6f
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NWD1 ANKRD18B FHAD1 CROCC PCDH7 CFAP46 DNAH11

6.69e-071931147ea345d34440b25f65358a53dc72831998d1c3620
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

NWD1 SYNE1 FHAD1 DNAH12 CCDC191 CFAP46 DNAH11

6.93e-071941147b4ce60c06568123008b1081d644733cb91c28f51
ToppCellASK452-Epithelial-Ciliated|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

ST6GALNAC1 NWD1 FHAD1 DNAH12 CCDC191 CFAP46 DNAH11

6.93e-0719411475aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NWD1 IFT172 FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

6.93e-071941147a46238514bca920c3e3713d23c18ba24a09e2a29
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NWD1 IFT172 FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

7.17e-07195114707a6bcef6af93ed87df455dee624037cb75e011a
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SYNE1 FHAD1 DNAH12 CCDC191 FBXO15 CFAP46 DNAH11

7.68e-0719711476865f4831eb23794fb88a8649d48d497bbae3f44
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NWD1 SYNE1 CNTRL FHAD1 DNAH12 CFAP46 DNAH11

7.95e-071981147ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DRC7 ANKRD18B FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

8.50e-072001147af6a551f83808c1c839df7ba7b1702ca28ea6e1b
ToppCell(09)_Interm._secr.>cil.|World / shred by cell type by condition

DRC7 NWD1 SYNE1 CNTRL FHAD1 DNAH12 CRNN

8.50e-0720011473305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DRC7 ANKRD18B FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

8.50e-07200114773ac1cf40ddd764be1100cbfaaa29563665457d8
ToppCellCiliated_cells-A-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

DRC7 NWD1 DNAH12 CNTN5 CRNN CFAP46

2.56e-0615111469d03ce73af15ef40c592d19b36aff46bebc14c40
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DRC7 NWD1 FHAD1 FBXO15 CFAP46 DNAH11

2.87e-0615411464e3bc24043144143842627cacf6f90dda2228910
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DRC7 NWD1 FHAD1 FBXO15 CFAP46 DNAH11

2.87e-0615411467556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DRC7 PRUNE2 NWD1 KLHL11 FHAD1 DNAH12

3.45e-0615911465543f5aec6352a7c5923e55daf3ed40ff5cc0f0c
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANKRD18B FHAD1 DNAH12 CROCC CFAP46 DNAH11

4.74e-0616811469a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPTBN2 CSMD2 CADM2 DST PCDH7 CRAMP1

5.24e-061711146ea60d9e9df28ab991fbdb596784b44f6a9fc5827
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NWD1 IFT172 DNAH12 FBXO15 CFAP46 DNAH11

6.18e-061761146dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

NWD1 FHAD1 DNAH12 CRNN CFAP46 DNAH11

6.39e-061771146c38138fb5ad9766c2d240811210c854338cd612e
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DRC7 NWD1 FHAD1 DNAH12 CFAP46 DNAH11

6.60e-061781146de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH12 WDR97 CROCC CCDC191 CFAP46 DNAH11

6.60e-0617811463b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

DRC7 NWD1 FHAD1 DNAH12 CFAP46 DNAH11

7.49e-061821146fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NWD1 FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

8.22e-0618511465e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

NWD1 DNAH12 CNTN5 FBXO15 CFAP46 DNAH11

8.48e-061861146f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NWD1 FHAD1 DNAH12 ANKRD18A CFAP46 DNAH11

8.48e-06186114676033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DRC7 NWD1 FHAD1 DNAH12 CFAP46 DNAH11

8.74e-0618711469e10ed56090d82589bc457788282f664b70ace4b
ToppCell21-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

NWD1 FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

8.74e-0618711461a2178a195d078d1963947b327c6d0d4f2f48341
ToppCellCiliated_cells-B-HP_01|World / lung cells shred on cell class, cell subclass, sample id

DRC7 NWD1 DNAH12 CRNN FBXO15 CFAP46

8.74e-061871146bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

DRC7 FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

9.29e-061891146a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NWD1 FHAD1 DNAH12 CCDC191 CFAP46 DNAH11

9.29e-061891146cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

DRC7 NWD1 DNAH12 FBXO15 CFAP46 DNAH11

9.29e-06189114627329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCiliated|World / shred by cell class for parenchyma

FHAD1 DNAH12 CRNN FBXO15 CFAP46 DNAH11

9.29e-061891146711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCellEpithelial_cells-Ciliated_cells-A|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

NWD1 FHAD1 DNAH12 CRNN CFAP46 DNAH11

9.57e-061901146549d813a8f23b175875e53347928941f143e236c
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

NWD1 FHAD1 DNAH12 CRNN CFAP46 DNAH11

9.57e-061901146426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DRC7 NWD1 FHAD1 DNAH12 CFAP46 DNAH11

9.86e-061911146e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DRC7 NWD1 FHAD1 DNAH12 CFAP46 DNAH11

9.86e-0619111469d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellwk_15-18-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DRC7 NWD1 FHAD1 DNAH12 CFAP46 DNAH11

9.86e-061911146e81cd65dbf0ef1c2ab7088f73ce605d456dd3a7a
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DRC7 NWD1 FHAD1 DNAH12 CFAP46 DNAH11

9.86e-0619111461c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

SYNE1 FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

1.02e-051921146be592e661367affced9ebe80849b466e6adb3a34
ToppCellCiliated-cil-3|World / Class top

DRC7 IFT172 SYNE1 FHAD1 CRNN DNAH11

1.02e-0519211464989ebb8812b8af1870599acd932849122c05a29
ToppCellmulticiliated|World / shred by cell class for turbinate

NWD1 FHAD1 DNAH12 CRNN CFAP46 DNAH11

1.02e-0519211460f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCellASK452-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

ST6GALNAC1 FHAD1 DNAH12 CCDC191 CFAP46 DNAH11

1.05e-051931146c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

NWD1 SYNE1 FHAD1 DNAH12 CFAP46 DNAH11

1.05e-051931146ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NWD1 FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

1.08e-051941146756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SYNE1 FHAD1 DNAH12 CCDC191 CFAP46 DNAH11

1.08e-0519411467a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NWD1 FHAD1 DNAH12 CROCC CFAP46 DNAH11

1.11e-05195114679dc031258579ea328181dda33710dd897f1064a
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NWD1 SYNE1 FHAD1 DNAH12 CFAP46 DNAH11

1.11e-0519511463486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NWD1 FHAD1 DNAH12 CCDC191 CFAP46 DNAH11

1.11e-0519511469651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DRC7 NWD1 IFT172 FHAD1 DNAH12 DNAH11

1.14e-051961146a37ba02446eef5d1fab703204583f6550a8ec3e1
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DRC7 NWD1 IFT172 FHAD1 DNAH12 DNAH11

1.14e-051961146a156840330630e518bc85633dded6f2c3ead3b30
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DRC7 NWD1 IFT172 FHAD1 DNAH12 DNAH11

1.14e-05196114689ea4d2086e1c769c5a87f1471a6cd4acabcfe33
ToppCell(05)_Ciliated|World / shred by cell type and Timepoint

DRC7 IFT172 SYNE1 FHAD1 DNAH12 CRNN

1.18e-051971146fee3cd16af8eea697cd64e8f64af505aaa2ac4b0
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NWD1 SYNE1 FHAD1 DNAH12 CFAP46 DNAH11

1.18e-05197114671fea4aa6ce96c7693fa94792d08770622873850
ToppCelldistal-Hematologic-Platelet/Megakaryocyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NWD1 IFT172 DNAH12 CCDC191 FBXO15 DNAH11

1.18e-051971146751ffb8792058384079ebfe94872b3525f1aea84
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 FHAD1 DNAH12 CCDC191 CFAP46 DNAH11

1.18e-05197114674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRUNE2 SYNE1 DGKG DYSF PCDH7 DNAH11

1.21e-051981146c12e7511628db819a52959bb68580e27c00c2e41
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

CNTRL DARS1 CEP350 UBE3A KIF2A GOLGB1

1.21e-05198114676d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRUNE2 SYNE1 DGKG DYSF PCDH7 DNAH11

1.21e-05198114622e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NWD1 IFT172 DNAH12 GOLGB1 CFAP46 DNAH11

1.21e-051981146d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ST6GALNAC1 NWD1 DNAH12 PCDH7 CFAP46 DNAH11

1.25e-0519911461ee4010d8557564e25e8ee00b914c2dfd9037838
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHML USP38 OASL SLFN11 CYB5D1 NCKAP1L

1.25e-0519911465b6feacb0ca92c3fc6b327be978320426dcf6f68
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

CNTRL CEP350 FHAD1 ANKRD18A PCDH7 GOLGB1

1.25e-05199114661b1ed2db71b96157b92b7535d1955a4033098da
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ST6GALNAC1 NWD1 DNAH12 PCDH7 CFAP46 DNAH11

1.25e-0519911461df69c0cb5f759f6a2152521842506a75bb95cae
ToppCellMild-Epithelial-Epithelial-|Mild / Condition, Lineage, Cell class and cell subclass

ST6GALNAC1 NWD1 DNAH12 PCDH7 CFAP46 DNAH11

1.25e-05199114681115bbd2c10bfdd38376d2075f03a59c31870d2
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DRC7 NWD1 FHAD1 DNAH12 FBXO15 CFAP46

1.25e-0519911462498237b9e895ca4826a3378d9d40989968df72b
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ST6GALNAC1 NWD1 DNAH12 PCDH7 CFAP46 DNAH11

1.25e-05199114674087b4b5e567310fc4ac58fb267ff651a180680
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ST6GALNAC1 NWD1 DNAH12 PCDH7 CFAP46 DNAH11

1.25e-05199114600b5ce099c50a5e1786ce2b3a06ee0931a8205a4
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DRC7 NWD1 FHAD1 DNAH12 FBXO15 CFAP46

1.25e-051991146542ec45c931b40738df1f3777b00c83be33a514a
ToppCellproximal-Epithelial-Ciliated|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NWD1 FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

1.25e-0519911469700f06e51ddca85e482b4f9bd4a79bfcd3cfb76
ToppCellMild-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

ST6GALNAC1 NWD1 DNAH12 PCDH7 CFAP46 DNAH11

1.25e-051991146ec5fff80e2a8a94fbaf1fdcc6d45c8d7c6252e18
ToppCellproximal-3-Epithelial-Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NWD1 FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

1.25e-0519911461188afad6fd5f01f9aeba225f611f38b237dd2c9
ToppCellMild-Epithelial-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

ST6GALNAC1 NWD1 DNAH12 PCDH7 CFAP46 DNAH11

1.25e-05199114691308b255783ad4029e5575028c18d7550832c51
ToppCelldistal-3-Epithelial-Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DRC7 NWD1 DNAH12 FBXO15 CFAP46 DNAH11

1.25e-0519911467e5f29f4ec1fea92f2c0064eea151d2d474ef904
ToppCellproximal-Epithelial-Ciliated-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NWD1 FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

1.25e-0519911462e8ace105c4e2405baa06d953e52888b54e2d055
ToppCellMild_COVID-19-Epithelial|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

ST6GALNAC1 NWD1 DNAH12 PCDH7 CFAP46 DNAH11

1.25e-05199114672689bda7476930887ae007682fcab27f956f050
ToppCell(10)_Ciliated|World / shred by cell type by condition

DRC7 NWD1 SYNE1 DNAH12 CRNN FBXO15

1.28e-0520011461b6a8025bd2746b626040058c122b1be3ab2fa61
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SPTBN1 DST GAN PCDH7 HSPB1 GOLGB1

1.28e-05200114697f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DRC7 FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

1.28e-05200114631d75c26055177d656df1fbb10b764cebd61e122
ToppCelldistal-3-Hematologic-Platelet/Megakaryocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NWD1 IFT172 ANKRD18B DNAH12 FBXO15 DNAH11

1.28e-052001146f5f5a8b0e4d802d95dc42646dd5e7d7daaad72b4
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NWD1 FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

1.28e-0520011465abd6d81e1cc354484ae693fcd708d78926e75b5
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DRC7 FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

1.28e-052001146e1dce91c6c531bb212002a14705e496d77ad3490
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NWD1 FHAD1 DNAH12 FBXO15 CFAP46 DNAH11

1.28e-0520011469c9d2b0276c7b0709c2eeeb0673a2f58106fb14e
ToppCellprimary_visual_cortex|World / Per Region, Lineage, Cell class, Cell type, Cell subtype

DGKG EML5 TIAM1 TRIM9 RIMS2

3.14e-051411145605d7b28e99c943f64b4095855a6f9f70e92cb09
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO1 SPTBN2 KY XKRX PCDH7

3.59e-051451145bfa196ac1db7acbfcbb2ba9f137036a95e16e091
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NWD1 FHAD1 FBXO15 CFAP46 DNAH11

3.96e-051481145d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NWD1 FHAD1 FBXO15 CFAP46 DNAH11

3.96e-051481145c8e93b87212f55774223caa385859c566fa1981f
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Cerebellum / BrainAtlas - Mouse McCarroll V32

TEX14 RET EML5 MAP3K9 DNAH11

4.09e-0514911456e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DRC7 NWD1 FBXO15 CFAP46 DNAH11

4.36e-05151114581cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DRC7 NWD1 FBXO15 CFAP46 DNAH11

4.36e-0515111459cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DRC7 NWD1 FBXO15 CFAP46 DNAH11

4.79e-0515411459ca71d440c4f87781e6525b8141e7d8d470b6a8e
DrugSertaconazole nitrate [99592-39-9]; Down 200; 8uM; MCF7; HT_HG-U133A

B3GNTL1 SPTBN1 DYSF LRCH1 EML3 MAP3K9 POLL TRPV6 RIMS2

5.47e-0719411396811_DN
Drug(+,-)-Synephrine [94-07-5]; Down 200; 24uM; HL60; HT_HG-U133A

SYNE1 RET LRCH1 CLCN4 TRIM9 POLL TRPV6 PRMT7

5.73e-0619411386156_DN
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTBN1 SPTBN2

7.93e-0541082DOID:0050882 (implicated_via_orthology)
Diseaseatrioventricular septal defect (implicated_via_orthology)

IFT172 DNAH11

2.75e-0471082DOID:0050651 (implicated_via_orthology)
DiseaseIschemic stroke

LRCH1 SLC22A7 EML5 USP38 ANKRD18A DNAH11

1.25e-033241086HP_0002140
DiseaseSchizophrenia

ST6GALNAC1 SPTBN2 SREBF1 CSMD2 ALS2CL EML5 KIF2A RIMS2 B3GAT2 DNMT3L

1.51e-0388310810C0036341
Diseasemuscular dystrophy (is_implicated_in)

SYNE1 DYSF

1.74e-03171082DOID:9884 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
WEVTEESLHSLQERL

ALS2CL

61

Q60I27
DHISLILAVDWLVDR

SLC1A5

451

Q15758
ERVRTLQEEERWCES

CNTRL

2001

Q7Z7A1
DLELVLWRADDVSRH

ANKRD18A

441

Q8IVF6
VFDTEEVHDVLRIWD

CSMD2

1316

Q7Z408
RSRHWALVSEEELSL

DNMT3L

331

Q9UJW3
DDLRINLWHLEITDR

PPP2R2A

196

P63151
LELVLWRADDVSRHE

ANKRD18B

451

A2A2Z9
EDVVFHLRWAVEILL

CFAP46

1236

Q8IYW2
ERIILHAIESVVIEW

DNAH11

236

Q96DT5
HTIDWLREKSRDTDR

CLCN4

31

P51793
ERGEAEWHKLLIEER

CCDC144CP

1001

Q8IYA2
VEDVELVSLHDLGRW

CACTIN-AS1

121

Q8N1I8
LEVGVLESIWEILHR

CYB5D1

151

Q6P9G0
AIIEEAEIRWSEVSR

CCDC113

131

Q9H0I3
AEIRWSEVSREVHEF

CCDC113

136

Q9H0I3
EAEEWLSSLRAHVVR

POLL

36

Q9UGP5
RRHELVIAWEPVSEE

CNTN5

786

O94779
RIDEKEWEVLRDHLT

NWD1

81

Q149M9
WQDLIHETEEAITLR

CHML

76

P26374
EREKWIHALEETILR

OSBPL9

86

Q96SU4
TTAILDREIWAETRL

DCHS1

2231

Q96JQ0
QELWEEARIRHEEIR

KIAA1755

1031

Q5JYT7
VFIWENIHTLVEERE

DST

6136

Q03001
LQEAHTDLERVRAIW

KY

176

Q8NBH2
HRLERAAAESERWEL

LONRF1

36

Q17RB8
DVIVDLWEGRHVARV

IL17RE

521

Q8NFR9
QDELVDHRLTEREWA

CBFA2T2

331

O43439
HLQRWIDISLEEIES

IGBP1

196

P78318
WLSVLHRIDREEVNQ

PCDH7

366

O60245
HEIKAWEDRLIRIQE

DNAH12

886

Q6ZR08
IRDEVTWLVRHTENV

NCKAP1L

376

P55160
RIEEDVHWQTEGIIS

LRCH1

426

Q9Y2L9
SEIRHTADRWRVSLD

HSPB1

86

P04792
EISEWLERHPREVVI

PLCXD1

136

Q9NUJ7
EWVDDHSRETVILRL

CRNN

441

Q9UBG3
HVPEAEREEVRDWVL

IFT172

1636

Q9UG01
HREWKEEVLDAVRTV

OASL

26

Q15646
LEITLWDQARVREEE

RIMS2

891

Q9UQ26
EDHRAVFQESIRWLE

KIF2A

626

O00139
RVPHELIECWTLEER

KCTD18

226

Q6PI47
DRARVVEHWIKVARE

RGL4

291

Q8IZJ4
DRWHLEVIPREEVEN

DGKG

556

P49619
WSAQRRALVEEEITR

GAK

206

O14976
SWIELEEDHLARVEE

HSPBAP1

271

Q96EW2
VVRREWHNLISEEKT

GSAP

546

A4D1B5
RVTRREDLTHALVWE

CEFIP

1106

Q711Q0
LEHREAAWRREEESF

CROCC

271

Q5TZA2
LDVLRHALSWLEEVE

FHAD1

606

B1AJZ9
FHLIRDWLSDLEITV

KLHL11

246

Q9NVR0
LEELRADSAHWEDAR

C20orf202

66

A1L168
SLHAVVVEFRDLWRI

PRMT7

516

Q9NVM4
AEGRVHVELVWIRET

FBXO15

471

Q8NCQ5
FEAVIRWIAHDTEIR

GAN

196

Q9H2C0
LHWILVEDAAARSEL

B3GAT2

111

Q9NPZ5
EIAAEHSDRRILWIT

CCDC191

861

Q8NCU4
WALHEVRVRKTLEER

CRAMP1

366

Q96RY5
RIELVRASWHELSIS

CADM2

76

Q8N3J6
HAEELLEWKRRLDAE

CEP350

1871

Q5VT06
WTAHREEIARISQDL

CEP170P1

21

Q96L14
RHQVWESELEVLEIL

DRC7

686

Q8IY82
RWLLLDTETHDLVAI

EML2

441

O95834
RWLVLDTETREIVSD

EML3

661

Q32P44
DRSVRIWSLVDHALI

EML5

346

Q05BV3
DLADIEDTVEWRHRN

FBXL5

486

Q9UKA1
LEEQGATWRHRETLI

FATE1

151

Q969F0
VTVSDGRWHDLRLEL

CELSR3

1841

Q9NYQ7
LEWLDVEHRTVAGVL

SLC22A7

221

Q9Y694
IRIIDWDRLTHNDIV

DYSF

461

O75923
EKELRTWEEELTRAA

MAP3K9

441

P80192
ELLTHLERRWTEIED

TBRG4

206

Q969Z0
LERRWTEIEDSHTLV

TBRG4

211

Q969Z0
EAVELRSLWREHACV

PRXL2B

21

Q8TBF2
RHRTLTAEEAEEEWE

GTF2F1

151

P35269
DWEHIRERPAAISIE

STK38

386

Q15208
DRWEVILADEHGIIA

TDRD6

1456

O60522
RAHSTLDEDLERWLQ

TEX14

1401

Q8IWB6
TAEEEREDNRLWRTV

PRUNE2

2871

Q8WUY3
RWGDSVLLVDLTHEE

MRPL4

211

Q9BYD3
VDREINRLEVTWDDT

SYNE1

2056

Q8NF91
QELESDIQLTHRRVW

NHS

151

Q6T4R5
WDEVSVLDDQRRLTR

EPHB6

56

O15197
DVLEEAYTTEHWLVR

STT3A

676

P46977
LEREVWKRLHDEGII

ST6GALNAC1

571

Q9NSC7
SLWRDLISEHRGLEE

SLFN11

411

Q7Z7L1
ADEVVWVRARVHTSR

DARS1

56

P14868
IHSDRWREALLLLED

PRORP

221

O15091
WERLEKAEHERELAL

SPTBN1

396

Q01082
EWLRLILEVHQFSRD

SPTBN1

2011

Q01082
AVVIHWLRRDEEAAE

SREBF1

881

P36956
LETTIWTHRVRFLEE

B3GNTL1

241

Q67FW5
TITDQIRLWELERDR

GTF2H4

386

Q92759
HLEVHWSLISVDVRR

SENP3

461

Q9H4L4
VHVSSERSLPEEEWR

ZFHX4

896

Q86UP3
TRDSVLIREFWEIVH

UBE3A

781

Q05086
EAVALVEDWHRETRT

ZSCAN20

121

P17040
LESASEEVIWVRRED

TIAM1

1566

Q13009
EKLRDLHRRWDELET

SPTBN2

1356

O15020
FDLHAWTLVDVRRDL

WDR97

276

A6NE52
GEVIAAHRILIWTED

WDR72

261

Q3MJ13
VYIWEIETGTLERHE

WDR72

581

Q3MJ13
TEEELSVLESCLHRW

USP25

541

Q9UHP3
CLHRWRTEIENDTRD

USP25

551

Q9UHP3
AHERDELWRAQIVAT

TRPV6

626

Q9H1D0
DVAIDFSREEWRHLD

ZNF585B

31

Q52M93
TELRAWHRALRTVIE

ARHGAP9

421

Q9BRR9
RLDLDSTEWDDIHVV

ARHGAP9

616

Q9BRR9
RREVSSLTARWHQEE

TSKS

331

Q9UJT2
IVRKVVESAEHWLDE

USP38

21

Q8NB14
DVAIDFSREEWRHLD

ZNF585A

31

Q6P3V2
LEVSTRWALDREQRE

RET

221

P07949
EEKRVRTRLEQVHEW

ZNFX1

1726

Q9P2E3
SDALIRRVHLTEDQW

TRIM9

386

Q9C026
RTLYREVTLETWEHI

ZNF544

36

Q6NX49
TRLRVSTEESLHQWE

ZNF502

116

Q8TBZ5
VIERDVVSGSEVLHW

STARD7

201

Q9NQZ5
LVDELTRWLQEFTRH

PIEZO1

1521

Q92508
EEVLIEWEVGHSIRT

XKRX

146

Q6PP77
RSVQRWREALEVEES

PJA2

341

O43164
LLESREVSRDLHHWI

WDR81

531

Q562E7
QRHLIEATRDWDVLS

ZNF518B

1056

Q9C0D4
EQIRRLEHSEWDSSR

GOLGB1

3176

Q14789