Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF853 VEZF1 NFAT5 CLOCK RFX3 ZNF384 ZFHX3 AR KMT2D	9.21e-06	1412	22	9	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF853 VEZF1 NFAT5 CLOCK RFX3 ZNF384 ZFHX3 AR ATXN3	1.20e-05	1459	22	9	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	VEZF1 NFAT5 CLOCK ZNF384 AR KMT2D	2.41e-05	560	22	6	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	VEZF1 NFAT5 CLOCK ZNF384 AR KMT2D	2.56e-05	566	22	6	GO:0001216
GeneOntologyMolecularFunction	chromatin binding	EP400 NFAT5 CLOCK AR CHD1 PHC1	1.13e-04	739	22	6	GO:0003682
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF853 NFAT5 CLOCK RFX3 ZNF384 ZFHX3 AR	2.66e-04	1244	22	7	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF853 NFAT5 CLOCK RFX3 ZNF384 ZFHX3 AR	3.04e-04	1271	22	7	GO:0000987
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	EP400 CHD1	7.54e-04	37	22	2	GO:0140658
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	AR KMT2D MAML2 SUPT20H EPC1 TCF20	1.26e-03	1160	22	6	GO:0030674
GeneOntologyMolecularFunction	histone modifying activity	CLOCK KMT2D ATXN3	1.95e-03	229	22	3	GO:0140993
GeneOntologyMolecularFunction	molecular adaptor activity	AR KMT2D MAML2 SUPT20H EPC1 TCF20	2.81e-03	1356	22	6	GO:0060090
GeneOntologyMolecularFunction	transcription coregulator activity	KMT2D MAML2 SUPT20H TCF20	3.03e-03	562	22	4	GO:0003712
GeneOntologyMolecularFunction	transcription coactivator activity	KMT2D MAML2 TCF20	4.30e-03	303	22	3	GO:0003713
GeneOntologyMolecularFunction	ATPase binding	AR ATXN3	6.24e-03	108	22	2	GO:0051117
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	EP400 CHD1	8.53e-03	127	22	2	GO:0008094
GeneOntologyMolecularFunction	transcription factor binding	NFAT5 CLOCK AR ATXN3	8.53e-03	753	22	4	GO:0008134
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	VEZF1 NFAT5 CLOCK RFX3 ZNF384 ZFHX3 AR PRDM10 KMT2D MAML2 SUPT20H EPC1 TCF20	1.57e-10	1390	22	13	GO:0045944
GeneOntologyBiologicalProcess	chromatin remodeling	EP400 NFAT5 CLOCK CHD1 KMT2D PHC1 EPC1	7.99e-06	741	22	7	GO:0006338
GeneOntologyBiologicalProcess	chromatin organization	EP400 NFAT5 CLOCK CHD1 KMT2D PHC1 EPC1	2.74e-05	896	22	7	GO:0006325
GeneOntologyBiologicalProcess	regulation of type B pancreatic cell development	CLOCK RFX3	4.86e-05	10	22	2	GO:2000074
GeneOntologyBiologicalProcess	protein-DNA complex organization	EP400 NFAT5 CLOCK CHD1 KMT2D PHC1 EPC1	5.50e-05	999	22	7	GO:0071824
GeneOntologyBiologicalProcess	positive regulation of intracellular estrogen receptor signaling pathway	AR KMT2D	7.12e-05	12	22	2	GO:0033148
GeneOntologyBiologicalProcess	regulation of intracellular steroid hormone receptor signaling pathway	CLOCK AR KMT2D	1.05e-04	87	22	3	GO:0033143
GeneOntologyBiologicalProcess	positive regulation of intracellular steroid hormone receptor signaling pathway	AR KMT2D	1.64e-04	18	22	2	GO:0033145
GeneOntologyBiologicalProcess	epithelial cell development	VEZF1 CLOCK RFX3 AR	1.72e-04	269	22	4	GO:0002064
GeneOntologyBiologicalProcess	DNA damage response	EP400 NFAT5 CLOCK SUPT20H EPC1 ATXN3	3.91e-04	959	22	6	GO:0006974
GeneOntologyBiologicalProcess	nuclear receptor-mediated steroid hormone signaling pathway	CLOCK AR KMT2D	3.94e-04	136	22	3	GO:0030518
GeneOntologyBiologicalProcess	type B pancreatic cell development	CLOCK RFX3	4.33e-04	29	22	2	GO:0003323
GeneOntologyBiologicalProcess	steroid hormone receptor signaling pathway	CLOCK AR KMT2D	5.77e-04	155	22	3	GO:0043401
GeneOntologyBiologicalProcess	regulation of intracellular estrogen receptor signaling pathway	AR KMT2D	6.69e-04	36	22	2	GO:0033146
GeneOntologyBiologicalProcess	type B pancreatic cell differentiation	CLOCK RFX3	9.11e-04	42	22	2	GO:0003309
GeneOntologyBiologicalProcess	glandular epithelial cell development	CLOCK RFX3	9.55e-04	43	22	2	GO:0002068
GeneOntologyBiologicalProcess	positive regulation of cell differentiation	VEZF1 NUMBL RFX3 ZFHX3 AR EPC1	9.81e-04	1141	22	6	GO:0045597
GeneOntologyBiologicalProcess	positive regulation of double-strand break repair via homologous recombination	EP400 EPC1	1.00e-03	44	22	2	GO:1905168
GeneOntologyBiologicalProcess	regulation of calcineurin-NFAT signaling cascade	NFAT5 CHERP	1.00e-03	44	22	2	GO:0070884
GeneOntologyBiologicalProcess	regulation of calcineurin-mediated signaling	NFAT5 CHERP	1.05e-03	45	22	2	GO:0106056
GeneOntologyBiologicalProcess	enteroendocrine cell differentiation	CLOCK RFX3	1.24e-03	49	22	2	GO:0035883
GeneOntologyBiologicalProcess	nuclear receptor-mediated signaling pathway	CLOCK AR KMT2D	1.24e-03	202	22	3	GO:0141193
GeneOntologyBiologicalProcess	calcineurin-NFAT signaling cascade	NFAT5 CHERP	1.50e-03	54	22	2	GO:0033173
GeneOntologyBiologicalProcess	estrogen receptor signaling pathway	AR KMT2D	1.67e-03	57	22	2	GO:0030520
GeneOntologyBiologicalProcess	calcineurin-mediated signaling	NFAT5 CHERP	1.73e-03	58	22	2	GO:0097720
GeneOntologyBiologicalProcess	regulation of DNA repair	EP400 SUPT20H EPC1	1.89e-03	234	22	3	GO:0006282
GeneOntologyBiologicalProcess	endocrine pancreas development	CLOCK RFX3	1.91e-03	61	22	2	GO:0031018
GeneOntologyBiologicalProcess	cellular response to steroid hormone stimulus	CLOCK AR KMT2D	2.01e-03	239	22	3	GO:0071383
GeneOntologyBiologicalProcess	hormone-mediated signaling pathway	CLOCK AR KMT2D	2.13e-03	244	22	3	GO:0009755
GeneOntologyBiologicalProcess	columnar/cuboidal epithelial cell development	CLOCK RFX3	2.44e-03	69	22	2	GO:0002066
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	CLOCK RFX3 ZFHX3 AR PHC1 EPC1	2.80e-03	1399	22	6	GO:0045892
GeneOntologyBiologicalProcess	circadian regulation of gene expression	CLOCK ZFHX3	2.87e-03	75	22	2	GO:0032922
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	CLOCK RFX3 ZFHX3 AR PHC1 EPC1	2.94e-03	1413	22	6	GO:1902679
GeneOntologyBiologicalProcess	positive regulation of DNA recombination	EP400 EPC1	3.26e-03	80	22	2	GO:0045911
GeneOntologyBiologicalProcess	regulation of cellular response to stress	EP400 SUPT20H EPC1 ATXN3	3.38e-03	598	22	4	GO:0080135
GeneOntologyBiologicalProcess	positive regulation of epithelial cell differentiation	VEZF1 RFX3	3.43e-03	82	22	2	GO:0030858
GeneOntologyBiologicalProcess	regulation of double-strand break repair via homologous recombination	EP400 EPC1	3.51e-03	83	22	2	GO:0010569
GeneOntologyCellularComponent	chromatin	EP400 NFAT5 CLOCK RFX3 ZFHX3 AR CHD1 PRDM10 PHC1 SUPT20H EPC1	3.93e-08	1480	21	11	GO:0000785
GeneOntologyCellularComponent	nuclear body	EP400 ZFHX3 AR PHC1 MAML2 EPC1 TCF20 MAMLD1	1.45e-06	903	21	8	GO:0016604
GeneOntologyCellularComponent	histone acetyltransferase complex	EP400 SUPT20H EPC1	1.10e-04	94	21	3	GO:0000123
GeneOntologyCellularComponent	protein acetyltransferase complex	EP400 SUPT20H EPC1	1.49e-04	104	21	3	GO:0031248
GeneOntologyCellularComponent	acetyltransferase complex	EP400 SUPT20H EPC1	1.71e-04	109	21	3	GO:1902493
GeneOntologyCellularComponent	transcription regulator complex	NFAT5 CLOCK RFX3 ZFHX3 PRDM10	2.58e-04	596	21	5	GO:0005667
GeneOntologyCellularComponent	H4/H2A histone acetyltransferase complex	EP400 EPC1	4.68e-04	32	21	2	GO:0043189
GeneOntologyCellularComponent	NuA4 histone acetyltransferase complex	EP400 EPC1	4.68e-04	32	21	2	GO:0035267
GeneOntologyCellularComponent	H4 histone acetyltransferase complex	EP400 EPC1	9.27e-04	45	21	2	GO:1902562
GeneOntologyCellularComponent	nuclear chromosome	EP400 CLOCK CHD1	2.01e-03	254	21	3	GO:0000228
GeneOntologyCellularComponent	transferase complex	EP400 KMT2D PHC1 SUPT20H EPC1	2.25e-03	963	21	5	GO:1990234
GeneOntologyCellularComponent	nucleosome	EP400 EPC1	8.37e-03	138	21	2	GO:0000786
GeneOntologyCellularComponent	nuclear speck	EP400 AR MAML2	8.78e-03	431	21	3	GO:0016607
HumanPheno	Ventral shortening of foreskin	AR MAMLD1	3.47e-06	2	10	2	HP:0012435
HumanPheno	Blind vagina	AR MAMLD1	3.46e-05	5	10	2	HP:0040314
HumanPheno	Androgen insufficiency	AR MAMLD1	3.46e-05	5	10	2	HP:0008226
HumanPheno	Abnormal preputium morphology	AR KMT2D MAMLD1	3.76e-05	36	10	3	HP:0100587
HumanPheno	Urethral diverticulum	AR MAMLD1	5.18e-05	6	10	2	HP:0008722
MousePheno	advanced circadian behavior phase	CLOCK ZFHX3	1.75e-05	5	19	2	MP:0020474
MousePheno	arrhythmic circadian behavior persistence	CLOCK ZFHX3	6.27e-05	9	19	2	MP:0020472
MousePheno	abnormal circadian behavior persistence	CLOCK ZFHX3	9.56e-05	11	19	2	MP:0020471
MousePheno	prolonged circadian behavior period	CLOCK ZFHX3	1.58e-04	14	19	2	MP:0020469
Domain	EPHD	KMT2D TCF20	3.02e-04	22	22	2	PS51805
Domain	SNF2_N	EP400 CHD1	6.43e-04	32	22	2	PF00176
Domain	SNF2_N	EP400 CHD1	6.43e-04	32	22	2	IPR000330
Domain	DNA/RNA_helicase_DEAH_CS	EP400 CHD1	7.70e-04	35	22	2	IPR002464
Domain	DEAH_ATP_HELICASE	EP400 CHD1	9.08e-04	38	22	2	PS00690
Domain	-	ZNF853 VEZF1 ZNF384 ZFHX3 PRDM10	9.85e-04	679	22	5	3.30.160.60
Domain	zf-C2H2	ZNF853 VEZF1 ZNF384 ZFHX3 PRDM10	1.08e-03	693	22	5	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF853 VEZF1 ZNF384 ZFHX3 PRDM10	1.09e-03	694	22	5	IPR013087
Domain	SET_dom	PRDM10 KMT2D	1.57e-03	50	22	2	IPR001214
Domain	SET	PRDM10 KMT2D	1.57e-03	50	22	2	PS50280
Domain	ZINC_FINGER_C2H2_2	ZNF853 VEZF1 ZNF384 ZFHX3 PRDM10	1.77e-03	775	22	5	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF853 VEZF1 ZNF384 ZFHX3 PRDM10	1.79e-03	777	22	5	PS00028
Domain	Znf_C2H2-like	ZNF853 VEZF1 ZNF384 ZFHX3 PRDM10	2.00e-03	796	22	5	IPR015880
Domain	Znf_C2H2	ZNF853 VEZF1 ZNF384 ZFHX3 PRDM10	2.10e-03	805	22	5	IPR007087
Domain	ZnF_C2H2	ZNF853 VEZF1 ZNF384 ZFHX3 PRDM10	2.13e-03	808	22	5	SM00355
Domain	PHD	KMT2D TCF20	4.87e-03	89	22	2	SM00249
Domain	Znf_PHD	KMT2D TCF20	5.09e-03	91	22	2	IPR001965
Domain	ZF_PHD_2	KMT2D TCF20	5.53e-03	95	22	2	PS50016
Domain	ZF_PHD_1	KMT2D TCF20	5.65e-03	96	22	2	PS01359
Domain	Helicase_C	EP400 CHD1	6.97e-03	107	22	2	PF00271
Domain	HELICc	EP400 CHD1	6.97e-03	107	22	2	SM00490
Domain	Helicase_C	EP400 CHD1	7.10e-03	108	22	2	IPR001650
Domain	HELICASE_CTER	EP400 CHD1	7.22e-03	109	22	2	PS51194
Domain	HELICASE_ATP_BIND_1	EP400 CHD1	7.22e-03	109	22	2	PS51192
Domain	DEXDc	EP400 CHD1	7.22e-03	109	22	2	SM00487
Domain	Helicase_ATP-bd	EP400 CHD1	7.35e-03	110	22	2	IPR014001
Domain	Znf_FYVE_PHD	KMT2D TCF20	1.28e-02	147	22	2	IPR011011
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	ZFHX3 AR KMT2D PHC1 MAML2 EPC1 MAMLD1 ATXN3	2.01e-06	768	18	8	MM14851
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	ZFHX3 AR KMT2D PHC1 MAML2 EPC1 MAMLD1 ATXN3	1.68e-05	1022	18	8	MM15436
Pathway	REACTOME_CHROMATIN_MODIFYING_ENZYMES	EP400 CLOCK KMT2D SUPT20H EPC1	1.80e-05	272	18	5	M29619
Pathway	REACTOME_HATS_ACETYLATE_HISTONES	EP400 CLOCK SUPT20H EPC1	2.71e-05	142	18	4	M27233
Pathway	REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	MAML2 MAMLD1	6.89e-05	10	18	2	MM15535
Pathway	REACTOME_NOTCH2_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	MAML2 MAMLD1	1.01e-04	12	18	2	M27159
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3	ZFHX3 MAML2 MAMLD1	1.16e-04	76	18	3	MM15520
Pathway	REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	MAML2 MAMLD1	1.39e-04	14	18	2	M27808
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZFHX3 AR KMT2D PHC1 MAML2 EPC1 MAMLD1 ATXN3	1.53e-04	1387	18	8	M734
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS	MAML2 MAMLD1	1.83e-04	16	18	2	M27121
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3	ZFHX3 MAML2 MAMLD1	2.32e-04	96	18	3	M27784
Pathway	REACTOME_SIGNALING_BY_NOTCH1	MAML2 MAMLD1	2.33e-04	18	18	2	MM14775
Pathway	REACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	MAML2 MAMLD1	2.89e-04	20	18	2	M27881
Pathway	REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY	MAML2 MAMLD1	3.83e-04	23	18	2	MM14954
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_E2F6	PHC1 EPC1	4.54e-04	25	18	2	MM15546
Pathway	REACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	MAML2 MAMLD1	4.54e-04	25	18	2	M27880
Pathway	REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY	MAML2 MAMLD1	5.71e-04	28	18	2	M6177
Pathway	REACTOME_SIGNALING_BY_NOTCH2	MAML2 MAMLD1	7.94e-04	33	18	2	M604
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_E2F6	PHC1 EPC1	8.43e-04	34	18	2	M27826
Pathway	REACTOME_SIGNALING_BY_NOTCH	MAML2 MAMLD1	1.11e-03	39	18	2	MM14604
Pathway	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT	MAML2 MAMLD1	1.29e-03	42	18	2	M17541
Pathway	KEGG_NOTCH_SIGNALING_PATHWAY	NUMBL MAML2	1.61e-03	47	18	2	M7946
Pathway	PID_HES_HEY_PATHWAY	AR MAML2	1.68e-03	48	18	2	M288
Pathway	REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	MAML2 MAMLD1	1.68e-03	48	18	2	M611
Pathway	REACTOME_SIGNALING_BY_NOTCH3	MAML2 MAMLD1	1.75e-03	49	18	2	M618
Pathway	REACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER	MAML2 MAMLD1	2.44e-03	58	18	2	M29616
Pathway	WP_NOTCH_SIGNALING_WP61	NUMBL MAML2	2.70e-03	61	18	2	M39540
Pathway	REACTOME_FORMATION_OF_PARAXIAL_MESODERM	MAML2 MAMLD1	3.43e-03	69	18	2	M46439
Pathway	REACTOME_SIGNALING_BY_NOTCH1	MAML2 MAMLD1	3.94e-03	74	18	2	M616
Pathway	REACTOME_SIGNALING_BY_NOTCH4	MAML2 MAMLD1	4.81e-03	82	18	2	M594
Pathway	WP_DELTANOTCH_SIGNALING_PATHWAY	NUMBL MAML2	4.81e-03	82	18	2	MM15922
Pathway	WP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY	EP400 KMT2D PHC1	6.20e-03	301	18	3	MM15983
Pathway	WP_HDAC6_INTERACTIONS_IN_THE_CENTRAL_NERVOUS_SYSTEM	EP400 ATXN3	8.96e-03	113	18	2	M48336
Pubmed	cDNAs with long CAG trinucleotide repeats from human brain.	EP400 NUMBL ZNF384 KMT2D	1.05e-09	23	22	4	9225980
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	EP400 AR KMT2D EPC1 CHERP TCF20	1.33e-08	268	22	6	33640491
Pubmed	PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.	EP400 KMT2D PHC1 EPC1	7.92e-08	65	22	4	22496869
Pubmed	Genetic interaction mapping in mammalian cells using CRISPR interference.	EP400 KMT2D PHC1 EPC1	1.01e-07	69	22	4	28481362
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	EP400 VEZF1 KMT2D SUPT20H EPC1 TCF20	1.38e-07	398	22	6	35016035
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	EP400 ZNF384 KMT2D TCF20	2.13e-07	83	22	4	28794006
Pubmed	AR imposes different effects on ZFHX3 transcription depending on androgen status in prostate cancer cells.	ZFHX3 AR	3.82e-07	2	22	2	34953044
Pubmed	Pathogenic variations in MAML2 and MAMLD1 contribute to congenital hypothyroidism due to dyshormonogenesis by regulating the Notch signalling pathway.	MAML2 MAMLD1	3.82e-07	2	22	2	36898841
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	VEZF1 NFAT5 CLOCK RFX3 ZFHX3 PHC1 TCF20	4.48e-07	808	22	7	20412781
Pubmed	The candidate splicing factor Sfswap regulates growth and patterning of inner ear sensory organs.	NUMBL MAML2 MAMLD1	5.66e-07	26	22	3	24391519
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	EP400 VEZF1 CLOCK KMT2D SUPT20H EPC1 CHERP TCF20	7.21e-07	1294	22	8	30804502
Pubmed	A census of human transcription factors: function, expression and evolution.	NFAT5 CLOCK RFX3 ZNF384 ZFHX3 AR KMT2D	9.78e-07	908	22	7	19274049
Pubmed	Pax6 represses androgen receptor-mediated transactivation by inhibiting recruitment of the coactivator SPBP.	AR TCF20	1.15e-06	3	22	2	21935435
Pubmed	CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis.	AR CHD1	1.15e-06	3	22	2	30930119
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	EP400 SUPT20H EPC1 TCF20	1.46e-06	134	22	4	25452129
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	EP400 ZNF384 CHD1 KMT2D TCF20	2.02e-06	341	22	5	32971831
Pubmed	Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocation.	AR CHD1	2.29e-06	4	22	2	26751641
Pubmed	Interaction network of human early embryonic transcription factors.	EP400 ZFHX3 KMT2D EPC1 TCF20	2.33e-06	351	22	5	38297188
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	EP400 KMT2D PHC1 EPC1	2.74e-06	157	22	4	30186101
Pubmed	Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats.	KMT2D CHERP	5.72e-06	6	22	2	8896557
Pubmed	Polyglutamine tracts regulate beclin 1-dependent autophagy.	AR ATXN3	5.72e-06	6	22	2	28445460
Pubmed	The ins and outs of a polyglutamine neurodegenerative disease: spinocerebellar ataxia type 1 (SCA1).	AR ATXN3	8.01e-06	7	22	2	10860780
Pubmed	Comparison of the number of triplets in SCA1, MJD/SCA3, HD, SBMA, DRPLA, MD, FRAXA and FRDA genes in schizophrenic patients and a healthy population.	AR ATXN3	8.01e-06	7	22	2	11121205
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	ZFHX3 AR KMT2D TCF20	1.04e-05	220	22	4	35785414
Pubmed	The mutational landscape of lethal castration-resistant prostate cancer.	AR KMT2D	1.07e-05	8	22	2	22722839
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	EP400 CHD1 SUPT20H TCF20	1.08e-05	222	22	4	37071664
Pubmed	Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract.	AR ATXN3	1.37e-05	9	22	2	9535906
Pubmed	Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.	AR KMT2D TCF20	1.62e-05	78	22	3	28611094
Pubmed	SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells.	EP400 AR	1.71e-05	10	22	2	18087039
Pubmed	Human transcription factor protein interaction networks.	EP400 VEZF1 ZFHX3 KMT2D SUPT20H EPC1 TCF20	1.93e-05	1429	22	7	35140242
Pubmed	The highly conserved and multifunctional NuA4 HAT complex.	EP400 EPC1	2.09e-05	11	22	2	15196461
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	EP400 VEZF1 ZNF384 CHD1 CHERP TCF20	2.15e-05	954	22	6	36373674
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	EP400 NFAT5 ZNF384 ZFHX3 CHERP	2.71e-05	583	22	5	29844126
Pubmed	Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.	NUMBL CLOCK PRDM10 TCF20	2.80e-05	283	22	4	18854154
Pubmed	The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.	EP400 KMT2D	2.97e-05	13	22	2	16510874
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	VEZF1 ZNF384 CHD1 PHC1 TCF20	3.31e-05	608	22	5	36089195
Pubmed	Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.	EP400 KMT2D	3.99e-05	15	22	2	16510875
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	EP400 VEZF1 NUMBL SUPT20H CHERP TCF20	4.35e-05	1082	22	6	38697112
Pubmed	Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development.	AR MAMLD1	5.81e-05	18	22	2	23087174
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	VEZF1 NFAT5 ZFHX3 PHC1 TCF20	6.86e-05	709	22	5	22988430
Pubmed	H2A.Z.2.2 is an alternatively spliced histone H2A.Z variant that causes severe nucleosome destabilization.	EP400 EPC1	7.96e-05	21	22	2	22467210
Pubmed	Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex.	EP400 EPC1	8.76e-05	22	22	2	12963728
Pubmed	The Repeat Expansion Diseases: The dark side of DNA repair.	AR ATXN3	9.59e-05	23	22	2	26002199
Pubmed	MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks.	EP400 EPC1	9.59e-05	23	22	2	20332121
Pubmed	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.	EP400 EPC1	9.59e-05	23	22	2	14966270
Pubmed	CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism.	EP400 EPC1	9.59e-05	23	22	2	31281901
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	EP400 PHC1 CHERP TCF20	1.03e-04	396	22	4	26687479
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	EP400 RFX3 ZNF384 KMT2D	1.18e-04	410	22	4	26949251
Pubmed	TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.	ZNF384 ZFHX3 TCF20	1.19e-04	152	22	3	28192407
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZFHX3 KMT2D PHC1 TCF20	1.27e-04	418	22	4	34709266
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	VEZF1 CHD1 PRDM10 MAML2 SUPT20H EPC1	1.34e-04	1327	22	6	32694731
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	EP400 KMT2D PHC1	1.57e-04	167	22	3	20362541
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	EP400 NUMBL SUPT20H MAMLD1	1.60e-04	444	22	4	34795231
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	EP400 RFX3 PRDM10 KMT2D EPC1	1.67e-04	857	22	5	25609649
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	CLOCK RFX3 ZNF384 AR TCF20	1.86e-04	877	22	5	20211142
Pubmed	A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs.	EP400 EPC1	2.24e-04	35	22	2	20946988
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	EP400 NUMBL ZNF384 CHD1 CHERP	2.49e-04	934	22	5	33916271
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	EP400 VEZF1 NUMBL ZFHX3 CHD1 SUPT20H	2.59e-04	1497	22	6	31527615
Pubmed	Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis.	ZFHX3 SUPT20H	2.65e-04	38	22	2	28218735
Pubmed	Loss of Rearranged L-Myc Fusion (RLF) results in defects in heart development in the mouse.	AR KMT2D	2.65e-04	38	22	2	27930960
Pubmed	The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation.	EP400 EPC1	2.65e-04	38	22	2	27153538
Pubmed	Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.	EP400 EPC1	3.24e-04	42	22	2	35705031
Pubmed	Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis.	EP400 EPC1	3.24e-04	42	22	2	29028833
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	NFAT5 CLOCK RFX3 ZNF384	3.46e-04	544	22	4	28473536
Pubmed	Hdac6 regulates Tip60-p400 function in stem cells.	EP400 EPC1	4.23e-04	48	22	2	24302573
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	EPC1 TCF20 ATXN3	4.65e-04	242	22	3	34011540
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	EP400 VEZF1 ZNF384 KMT2D TCF20	5.34e-04	1103	22	5	34189442
Pubmed	New nomenclature for chromatin-modifying enzymes.	CLOCK KMT2D	5.97e-04	57	22	2	18022353
Interaction	FEV interactions	EP400 VEZF1 ZFHX3 KMT2D SUPT20H TCF20	4.64e-08	203	21	6	int:FEV
Interaction	TLE3 interactions	VEZF1 CLOCK ZFHX3 AR KMT2D CHERP TCF20	6.91e-08	376	21	7	int:TLE3
Interaction	SNRNP40 interactions	EP400 VEZF1 ZNF384 ZFHX3 CHD1 PRDM10 CHERP TCF20	1.35e-07	637	21	8	int:SNRNP40
Interaction	PLAC1 interactions	EP400 SUPT20H EPC1	1.95e-06	24	21	3	int:PLAC1
Interaction	CRX interactions	EP400 ZFHX3 KMT2D EPC1 TCF20	5.28e-06	254	21	5	int:CRX
Interaction	ELF4 interactions	EP400 KMT2D SUPT20H EPC1	5.59e-06	115	21	4	int:ELF4
Interaction	MED23 interactions	EP400 ZFHX3 AR SUPT20H EPC1	6.60e-06	266	21	5	int:MED23
Interaction	MYCL interactions	EP400 SUPT20H EPC1	1.64e-05	48	21	3	int:MYCL
Interaction	POU5F1 interactions	EP400 ZFHX3 AR CHD1 PHC1 TCF20	2.16e-05	584	21	6	int:POU5F1
Interaction	EGR2 interactions	EP400 ZFHX3 KMT2D EPC1	2.68e-05	171	21	4	int:EGR2
Interaction	KDM1A interactions	EP400 CLOCK ZFHX3 AR KMT2D PHC1 TCF20	3.09e-05	941	21	7	int:KDM1A
Interaction	NUP43 interactions	EP400 ZFHX3 CHD1 KMT2D EPC1 TCF20	3.17e-05	625	21	6	int:NUP43
Interaction	JAZF1 interactions	EP400 SUPT20H EPC1	3.38e-05	61	21	3	int:JAZF1
Interaction	LHX3 interactions	VEZF1 KMT2D TCF20 ATXN3	3.64e-05	185	21	4	int:LHX3
Interaction	HNF1B interactions	EP400 ZFHX3 KMT2D EPC1	4.04e-05	190	21	4	int:HNF1B
Interaction	AR interactions	EP400 ZFHX3 AR KMT2D EPC1 CHERP TCF20	4.34e-05	992	21	7	int:AR
Interaction	KLF5 interactions	EP400 AR KMT2D EPC1	4.47e-05	195	21	4	int:KLF5
Interaction	CIC interactions	EP400 NFAT5 ZNF384 ZFHX3 AR CHERP	4.79e-05	673	21	6	int:CIC
Interaction	SOX2 interactions	EP400 CLOCK RFX3 ZNF384 ZFHX3 KMT2D TCF20 ATXN3	5.34e-05	1422	21	8	int:SOX2
Interaction	PDE6A interactions	CLOCK CHERP	5.66e-05	11	21	2	int:PDE6A
Interaction	EPC1 interactions	EP400 AR EPC1	7.90e-05	81	21	3	int:EPC1
Interaction	NFIX interactions	EP400 ZFHX3 AR KMT2D	8.07e-05	227	21	4	int:NFIX
Interaction	KLF3 interactions	EP400 ZFHX3 KMT2D EPC1	8.21e-05	228	21	4	int:KLF3
Interaction	H3-3A interactions	VEZF1 ZNF384 AR CHD1 KMT2D TCF20	8.68e-05	749	21	6	int:H3-3A
Interaction	HDAC1 interactions	EP400 RFX3 ZFHX3 AR CHD1 KMT2D TCF20	8.76e-05	1108	21	7	int:HDAC1
Interaction	ASF1A interactions	EP400 ZNF384 KMT2D TCF20	1.15e-04	249	21	4	int:ASF1A
Interaction	MAX interactions	EP400 CLOCK KMT2D EPC1	1.19e-04	251	21	4	int:MAX
Interaction	RBPJ interactions	ZNF384 AR CHD1 MAML2	1.25e-04	254	21	4	int:RBPJ
Interaction	KLF6 interactions	EP400 SUPT20H EPC1	1.27e-04	95	21	3	int:KLF6
Interaction	KAT2B interactions	CLOCK AR SUPT20H ATXN3	1.28e-04	256	21	4	int:KAT2B
Interaction	H3C3 interactions	VEZF1 ZNF384 CHD1 PHC1 TCF20	1.29e-04	495	21	5	int:H3C3
Interaction	TRIM27 interactions	VEZF1 ZNF384 ZFHX3 EPC1 TCF20	1.54e-04	514	21	5	int:TRIM27
Interaction	HNF4A interactions	EP400 AR KMT2D EPC1	1.69e-04	275	21	4	int:HNF4A
Interaction	CEBPA interactions	EP400 VEZF1 ZNF384 AR CHD1 KMT2D TCF20	1.82e-04	1245	21	7	int:CEBPA
Interaction	MRGBP interactions	EP400 VEZF1 EPC1	1.91e-04	109	21	3	int:MRGBP
Interaction	KLF15 interactions	EP400 VEZF1 KMT2D EPC1	2.07e-04	290	21	4	int:KLF15
Interaction	TLX3 interactions	ZFHX3 AR KMT2D TCF20	2.10e-04	291	21	4	int:TLX3
Interaction	MAGED1 interactions	NUMBL AR CHERP ATXN3	2.21e-04	295	21	4	int:MAGED1
Interaction	TAF6L interactions	RFX3 AR SUPT20H	2.23e-04	115	21	3	int:TAF6L
Interaction	SP7 interactions	EP400 KMT2D EPC1 TCF20	2.48e-04	304	21	4	int:SP7
Interaction	SLX4 interactions	EP400 ZNF384 CHD1 SUPT20H TCF20	2.53e-04	572	21	5	int:SLX4
Interaction	ELK3 interactions	EP400 VEZF1 SUPT20H	2.53e-04	120	21	3	int:ELK3
Interaction	PARP1 interactions	EP400 ZNF384 AR CHD1 PHC1 CHERP ATXN3	2.57e-04	1316	21	7	int:PARP1
Interaction	ETS1 interactions	EP400 AR KMT2D	2.59e-04	121	21	3	int:ETS1
Interaction	H2BC8 interactions	EP400 ZNF384 CHD1 PHC1 TCF20	2.61e-04	576	21	5	int:H2BC8
Interaction	CREBBP interactions	CLOCK AR KMT2D MAML2 ATXN3	3.13e-04	599	21	5	int:CREBBP
Interaction	PAX9 interactions	ZFHX3 KMT2D TCF20	3.20e-04	130	21	3	int:PAX9
Interaction	KLF8 interactions	EP400 KMT2D SUPT20H EPC1	3.35e-04	329	21	4	int:KLF8
Interaction	CSNK2B interactions	EP400 CLOCK AR CHERP ATXN3	3.80e-04	625	21	5	int:CSNK2B
Interaction	PHF21A interactions	CLOCK ZFHX3 AR KMT2D	3.92e-04	343	21	4	int:PHF21A
Interaction	RNF4 interactions	VEZF1 ZNF384 AR CHD1 PHC1 CHERP TCF20	3.96e-04	1412	21	7	int:RNF4
Interaction	TLX2 interactions	ZFHX3 KMT2D TCF20	4.15e-04	142	21	3	int:TLX2
Interaction	SMC5 interactions	EP400 VEZF1 ZNF384 CHD1 CHERP TCF20	4.19e-04	1000	21	6	int:SMC5
Interaction	CBX3 interactions	EP400 VEZF1 CHD1 PRDM10 TCF20	4.42e-04	646	21	5	int:CBX3
Interaction	CEBPB interactions	VEZF1 NFAT5 ZNF384 AR KMT2D CHERP TCF20	4.52e-04	1443	21	7	int:CEBPB
Interaction	KAT5 interactions	EP400 CLOCK AR EPC1	4.61e-04	358	21	4	int:KAT5
Interaction	PYHIN1 interactions	ZNF384 CHD1 CHERP TCF20	4.61e-04	358	21	4	int:PYHIN1
Interaction	POU6F2 interactions	VEZF1 ZNF384 ZFHX3	4.68e-04	148	21	3	int:POU6F2
Interaction	BRD8 interactions	EP400 AR EPC1	4.78e-04	149	21	3	int:BRD8
Interaction	MEN1 interactions	EP400 ZNF384 CHD1 KMT2D CHERP TCF20	4.89e-04	1029	21	6	int:MEN1
Interaction	PAX6 interactions	EP400 ZFHX3 AR KMT2D	5.01e-04	366	21	4	int:PAX6
Interaction	ETV5 interactions	AR KMT2D	5.36e-04	33	21	2	int:ETV5
Interaction	ELF2 interactions	EP400 AR EPC1	5.46e-04	156	21	3	int:ELF2
Interaction	FASN interactions	VEZF1 CHD1 PRDM10 MAML2 SUPT20H ATXN3	5.78e-04	1062	21	6	int:FASN
Interaction	KLF4 interactions	AR KMT2D ATXN3	5.88e-04	160	21	3	int:KLF4
Interaction	SOX5 interactions	ZFHX3 KMT2D TCF20	6.10e-04	162	21	3	int:SOX5
Interaction	FHL2 interactions	EP400 NFAT5 RFX3 AR	6.74e-04	396	21	4	int:FHL2
Interaction	YAP1 interactions	NFAT5 AR CHD1 KMT2D TCF20 ATXN3	6.80e-04	1095	21	6	int:YAP1
Interaction	TLX1 interactions	ZFHX3 KMT2D TCF20	7.63e-04	175	21	3	int:TLX1
Interaction	MDC1 interactions	AR PHC1 TCF20 ATXN3	7.96e-04	414	21	4	int:MDC1
Interaction	H2BC1 interactions	EP400 EPC1 TCF20	8.01e-04	178	21	3	int:H2BC1
Interaction	NKX2-1 interactions	ZNF384 ZFHX3 TCF20	8.28e-04	180	21	3	int:NKX2-1
Interaction	YEATS4 interactions	EP400 CLOCK EPC1	8.55e-04	182	21	3	int:YEATS4
Interaction	WWTR1 interactions	EP400 CLOCK KMT2D TCF20	8.55e-04	422	21	4	int:WWTR1
Interaction	FOXR2 interactions	EP400 EPC1	8.68e-04	42	21	2	int:FOXR2
Interaction	LHX2 interactions	EP400 ZFHX3 KMT2D	8.68e-04	183	21	3	int:LHX2
Interaction	EP400 interactions	EP400 AR EPC1	8.82e-04	184	21	3	int:EP400
Interaction	E2F6 interactions	KMT2D PHC1 EPC1	8.96e-04	185	21	3	int:E2F6
Interaction	HIVEP1 interactions	VEZF1 ZFHX3 AR	9.10e-04	186	21	3	int:HIVEP1
Interaction	FOXR1 interactions	EP400 EPC1	9.53e-04	44	21	2	int:FOXR1
Interaction	DMAP1 interactions	EP400 AR EPC1	9.83e-04	191	21	3	int:DMAP1
Interaction	PRPF40A interactions	ZFHX3 AR CHERP ATXN3	1.05e-03	446	21	4	int:PRPF40A
Interaction	TRRAP interactions	EP400 CLOCK AR SUPT20H EPC1	1.10e-03	790	21	5	int:TRRAP
Interaction	PYGO2 interactions	AR KMT2D	1.13e-03	48	21	2	int:PYGO2
Interaction	DPY30 interactions	AR KMT2D PHC1	1.19e-03	204	21	3	int:DPY30
Interaction	PAGR1 interactions	AR KMT2D	1.28e-03	51	21	2	int:PAGR1
Interaction	NANOG interactions	EP400 PHC1 CHERP TCF20	1.39e-03	481	21	4	int:NANOG
Interaction	RELA interactions	ZFHX3 AR KMT2D ATXN3	1.43e-03	485	21	4	int:RELA
Interaction	POLR1G interactions	EP400 ZNF384 CHD1 TCF20	1.48e-03	489	21	4	int:POLR1G
Interaction	MORF4L1 interactions	EP400 VEZF1 EPC1	1.50e-03	221	21	3	int:MORF4L1
Interaction	RCOR1 interactions	CLOCK ZFHX3 AR KMT2D	1.53e-03	494	21	4	int:RCOR1
Interaction	ERG interactions	AR KMT2D TCF20	1.53e-03	223	21	3	int:ERG
Interaction	MECP2 interactions	EP400 VEZF1 NUMBL SUPT20H CHERP TCF20	1.58e-03	1287	21	6	int:MECP2
Interaction	HDAC2 interactions	EP400 RFX3 AR PHC1 TCF20	1.65e-03	865	21	5	int:HDAC2
Interaction	RNF2 interactions	EP400 AR KMT2D PHC1 EPC1	1.66e-03	866	21	5	int:RNF2
Interaction	H2AC4 interactions	EP400 PRDM10 KMT2D TCF20	1.67e-03	506	21	4	int:H2AC4
Interaction	MBTD1 interactions	EP400 EPC1	1.71e-03	59	21	2	int:MBTD1
Interaction	CTR9 interactions	VEZF1 AR CHD1	1.74e-03	233	21	3	int:CTR9
Interaction	RPS9 interactions	ZNF384 AR PRDM10 ATXN3	1.79e-03	515	21	4	int:RPS9
Interaction	H2BC10 interactions	EP400 EPC1	1.82e-03	61	21	2	int:H2BC10
Cytoband	Ensembl 112 genes in cytogenetic band chr16q22	NFAT5 ZFHX3	3.46e-03	183	22	2	chr16q22
Cytoband	Ensembl 112 genes in cytogenetic band chr12p13	ZNF384 PHC1	1.23e-02	353	22	2	chr12p13
GeneFamily	Ataxins\|Trinucleotide repeat containing	EP400 NUMBL ZNF384 KMT2D	6.68e-09	25	17	4	775
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF853 VEZF1 ZNF384 ZFHX3 PRDM10	4.05e-04	718	17	5	28
Coexpression	GSE11924_TFH_VS_TH1_CD4_TCELL_UP	RFX3 ZNF384 CHD1 KMT2D	2.12e-05	199	22	4	M3151
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	VEZF1 CLOCK ZFHX3 CHD1 SUPT20H MAMLD1	5.68e-05	856	22	6	M4500
Coexpression	GSE6259_33D1_POS_VS_DEC205_POS_FLT3L_INDUCED_SPLENIC_DC_UP	VEZF1 NFAT5 MAMLD1	4.10e-04	175	22	3	M6723
Coexpression	GSE29615_DAY3_VS_DAY7_LAIV_FLU_VACCINE_PBMC_UP	ZNF853 NFAT5 AR	5.14e-04	189	22	3	M4921
Coexpression	GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN	EP400 NFAT5 MAML2	5.14e-04	189	22	3	M3112
Coexpression	GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_UP	CHD1 KMT2D EPC1	5.38e-04	192	22	3	M8272
Coexpression	VANTVEER_BREAST_CANCER_BRCA1_DN	VEZF1 ZFHX3	5.41e-04	41	22	2	M3464
Coexpression	CHANGOLKAR_H2AFY_TARGETS_DN	AR CHERP	5.67e-04	42	22	2	M2290
Coexpression	GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_DN	RFX3 AR TCF20	5.88e-04	198	22	3	M5701
Coexpression	GSE22229_RENAL_TRANSPLANT_VS_HEALTHY_PBMC_DN	PHC1 ST6GALNAC5 EPC1	5.88e-04	198	22	3	M7480
Coexpression	GSE11057_CD4_CENT_MEM_VS_PBMC_UP	PHC1 SUPT20H TCF20	5.88e-04	198	22	3	M3116
Coexpression	CHANGOLKAR_H2AFY_TARGETS_DN	AR CHERP	5.95e-04	43	22	2	MM902
Coexpression	GSE31082_DN_VS_DP_THYMOCYTE_DN	NFAT5 CHD1 SUPT20H	6.06e-04	200	22	3	M5055
Coexpression	GSE41867_DAY8_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP	NFAT5 PHC1 EPC1	6.06e-04	200	22	3	M9449
Coexpression	GSE40655_FOXO1_KO_VS_WT_NTREG_UP	VEZF1 AR KMT2D	6.06e-04	200	22	3	M9439
Coexpression	GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN	CLOCK KMT2D SUPT20H	6.06e-04	200	22	3	M9463
Coexpression	GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA5_STIM_CD8_TCELL_UP	VEZF1 ZFHX3 KMT2D	6.06e-04	200	22	3	M8050
Coexpression	GSE29164_DAY3_VS_DAY7_CD8_TCELL_AND_IL12_TREATED_MELANOMA_UP	CLOCK ZFHX3 CHD1	6.06e-04	200	22	3	M8495
Coexpression	GSE8685_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN	PRDM10 PHC1 CHERP	6.06e-04	200	22	3	M330
Coexpression	GSE8685_IL2_ACT_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP	VEZF1 KMT2D CHERP	6.06e-04	200	22	3	M331
Coexpression	GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN	ZFHX3 PHC1 EPC1	6.06e-04	200	22	3	M7518
Coexpression	GSE360_CTRL_VS_L_DONOVANI_MAC_UP	ZNF384 ZFHX3 CHERP	6.06e-04	200	22	3	M5157
Coexpression	GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_2H_UP	NFAT5 MAML2 MAMLD1	6.06e-04	200	22	3	M8733
Coexpression	BROWNE_HCMV_INFECTION_48HR_DN	EP400 ZFHX3 AR ATXN3	6.35e-04	482	22	4	M12144
ToppCell	TCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3\|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9	NFAT5 ZNF384 KMT2D PHC1	5.44e-07	135	22	4	ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCell	facs-Marrow-T-cells-24m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD1 PRDM10 ST6GALNAC5	6.47e-05	160	22	3	b3f7ef7e682b48a83ca425f5c439336e96168300
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NUMBL PRDM10 ATXN3	8.58e-05	176	22	3	90f8bb11f339f67f08692a0c33dd420f5cda2861
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MAML2 SUPT20H ATXN3	1.01e-04	186	22	3	bbb8edea8d8bdc1a469faec1563e40b1f62d7f3d
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	ZFHX3 MAML2 ATXN3	1.09e-04	191	22	3	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF853 ST6GALNAC5 MAMLD1	1.11e-04	192	22	3	b2d9cc2a013012b25b458d4dc77be63e1c2144da
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF853 ST6GALNAC5 MAMLD1	1.11e-04	192	22	3	b18ae7337eaad1315a5b0ee81c75f7606bd3c7fe
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	EP400 AR PRDM10	1.23e-04	199	22	3	174f6013af6eafa577f84205a62927f2b367fda3
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF853 PHC1 MAMLD1	1.25e-04	200	22	3	36de49593cf6ff1c9229fcceb150c1d68658a360
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF853 NUMBL MAMLD1	1.25e-04	200	22	3	4c3c11dd5e71ebc3d62264eeaeb71a850b149779
Computational	Neighborhood of RBM8A	VEZF1 ZNF384 PHC1	3.10e-04	81	18	3	GCM_RBM8A
Computational	Neighborhood of MSH3	EP400 NFAT5 CLOCK ATXN3	6.07e-04	243	18	4	MORF_MSH3
Drug	glutamin	NFAT5 ZNF384 AR CHERP MAMLD1 ATXN3	3.78e-06	461	22	6	CID000000738
Drug	17-alpha-Hydroxyprogesterone	AR MAMLD1	3.20e-05	9	22	2	ctd:D019326
Drug	Dihydrostreptomycin sulfate [5490-27-7]; Down 200; 2.8uM; MCF7; HT_HG-U133A	ZFHX3 AR PRDM10 SUPT20H	3.59e-05	198	22	4	6228_DN
Drug	canrenone	VEZF1 AR	1.06e-04	16	22	2	CID000013789
Drug	AC1L9FY1	EP400 NFAT5 AR	1.23e-04	101	22	3	CID000444218
Drug	AC1L1HD4	AR TCF20	1.85e-04	21	22	2	CID000004079
Drug	reversine	AR PHC1	2.64e-04	25	22	2	CID000210332
Drug	trenbolone acetate	ZNF384 AR	3.56e-04	29	22	2	CID000066359
Drug	tert-butyl glutaminate	NFAT5 PHC1	4.91e-04	34	22	2	CID003450458
Drug	Methylene Chloride	NFAT5 CLOCK AR	5.02e-04	163	22	3	ctd:D008752
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	ZNF384 ZFHX3 PRDM10	5.77e-04	171	22	3	6879_DN
Drug	11-ketotestosterone	AR TCF20	6.13e-04	38	22	2	CID000104796
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	ZFHX3 AR ATXN3	8.20e-04	193	22	3	1652_UP
Drug	7 alpha, 17 alpha-dimethyl-19-nortestosterone	AR TCF20	8.23e-04	44	22	2	CID000019454
Drug	Disulfiram [97-77-8]; Down 200; 13.4uM; MCF7; HT_HG-U133A	AR SUPT20H ATXN3	8.32e-04	194	22	3	6210_DN
Drug	2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A_EA	EP400 NFAT5 SUPT20H	8.32e-04	194	22	3	1060_UP
Drug	Carbachol [51-83-2]; Up 200; 21.8uM; HL60; HT_HG-U133A	ZFHX3 AR MAMLD1	8.58e-04	196	22	3	3042_UP
Drug	Androstenedione	AR MAMLD1	8.60e-04	45	22	2	ctd:D000735
Drug	LY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A	NFAT5 SUPT20H ATXN3	8.70e-04	197	22	3	6935_DN
Drug	STOCK1N-35874; Down 200; 14uM; PC3; HT_HG-U133A	AR SUPT20H MAMLD1	8.70e-04	197	22	3	6561_DN
Drug	Sulfinpyrazone [57-96-5]; Down 200; 9.8uM; MCF7; HT_HG-U133A	NFAT5 AR SUPT20H	8.70e-04	197	22	3	6230_DN
Drug	Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A	ZFHX3 PRDM10 MAMLD1	8.70e-04	197	22	3	2667_UP
Drug	thioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	CLOCK AR MAMLD1	8.83e-04	198	22	3	6989_DN
Drug	Oxybutynin chloride [1508-65-2]; Up 200; 10.2uM; PC3; HT_HG-U133A	NFAT5 ZFHX3 SUPT20H	8.83e-04	198	22	3	7126_UP
Drug	Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Up 200; 5.8uM; HL60; HT_HG-U133A	RFX3 ZFHX3 KMT2D	8.96e-04	199	22	3	2543_UP
Disease	hypospadias (is_implicated_in)	AR MAMLD1	1.35e-05	8	21	2	DOID:10892 (is_implicated_in)
Disease	Malignant tumor of prostate	ZFHX3 AR	1.73e-05	9	21	2	cv:C0376358
Disease	prostate cancer (is_implicated_in)	ZFHX3 AR CHD1	7.67e-05	117	21	3	DOID:10283 (is_implicated_in)
Disease	Neoplasm of the genitourinary tract	ZFHX3 AR	1.32e-04	24	21	2	cv:C0042065
Disease	prostate cancer (implicated_via_orthology)	AR CHD1	2.51e-04	33	21	2	DOID:10283 (implicated_via_orthology)
Disease	asparagine measurement	RFX3 PHC1	3.89e-04	41	21	2	EFO_0009766
Disease	Male sterility	AR KMT2D	5.34e-04	48	21	2	C0917731
Disease	Male infertility	AR KMT2D	5.34e-04	48	21	2	C0021364
Disease	Subfertility, Male	AR KMT2D	5.34e-04	48	21	2	C0848676
Disease	cognitive inhibition measurement	PHC1 TCF20	5.79e-04	50	21	2	EFO_0007969
Disease	Mental Depression	CLOCK AR ATXN3	7.47e-04	254	21	3	C0011570
Disease	Prostatic Neoplasms	ZFHX3 AR CHD1 KMT2D	8.49e-04	616	21	4	C0033578
Disease	Malignant neoplasm of prostate	ZFHX3 AR CHD1 KMT2D	8.49e-04	616	21	4	C0376358
Disease	breast carcinoma (is_marker_for)	ZFHX3 KMT2D	1.01e-03	66	21	2	DOID:3459 (is_marker_for)
Disease	Depressive disorder	CLOCK AR ATXN3	1.09e-03	289	21	3	C0011581
Disease	vital capacity	ZNF853 NFAT5 ZFHX3 TCF20 ATXN3	1.48e-03	1236	21	5	EFO_0004312
Disease	balding measurement	CLOCK AR MAML2 EPC1	2.14e-03	792	21	4	EFO_0007825

Protein segments in the cluster

Peptide	Gene	Start	Entry
QQQQQQQQQTTTTSQ	EP400	2776	Q96L91
QQLAQIQQQQANSNS	EPC1	601	Q9H2F5
QQQQQQQQHQASSNS	CHD1	106	O14646
SQVAKAQQQQQQQQQ	NUMBL	421	Q9Y6R0
QQQQQQQQQQGDLSG	ATXN3	296	P54252
QQQQQQQQQQETSPR	AR	71	P10275
QQQQQETSPRQQQQQ	AR	76	P10275
SSTQGQALQQQQQQQ	PRDM10	1011	Q9NQV6
QALQQQQQQQQNSSV	PRDM10	1016	Q9NQV6
QSENTLSNQQQQQQQ	NFAT5	871	O94916
QQQQQQSILFSNQNT	NFAT5	1261	O94916
QQQQQQQQQQQSSIS	MAML2	611	Q8IZL2
QQQQQQSSISAQQQQ	MAML2	616	Q8IZL2
AQQQQQQQSSISAQQ	MAML2	626	Q8IZL2
QQQSSISAQQQQQQQ	MAML2	631	Q8IZL2
TSLAQQQQQQQQQQQ	CHERP	326	Q8IWX8
TSNLLSQQQQQQQQQ	MAMLD1	486	Q13495
TATLQLQQQQQQQQQ	MAMLD1	591	Q13495
VQQQVQQVQTVQQVQ	RFX3	36	P48380
QQQQQQQQQASATGS	ST6GALNAC5	41	Q9BVH7
QQSQTLSVTQQQQQQ	CLOCK	746	O15516
ASQASQQQQQQQQQQ	ZNF384	496	Q8TF68
ETSNQKQQQQQQQQQ	VEZF1	331	Q14119
QLSSAFQQQQQQIQQ	SUPT20H	721	Q8NEM7
QQQQQQQQQPQATTL	PHC1	431	P78364
QYQQQASSQQQQQQV	TCF20	166	Q9UGU0
QQQQEQLQTQQAQEQ	ZNF853	171	P0CG23
QQQQQQAQTLAQAQA	ZFHX3	1736	Q15911
QQQQQQLWQQQQATA	KMT2D	2811	O14686