Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

2.73e-27356114GO:0015020
GeneOntologyMolecularFunctionretinoic acid binding

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

1.72e-21286111GO:0001972
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

4.77e-191536115GO:0008194
GeneOntologyMolecularFunctionretinoid binding

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

1.73e-18486111GO:0005501
GeneOntologyMolecularFunctionhexosyltransferase activity

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 ALG8 UGT2B28 HAS2 UGT2B11

1.82e-182116116GO:0016758
GeneOntologyMolecularFunctionisoprenoid binding

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

2.22e-18496111GO:0019840
GeneOntologyMolecularFunctionglycosyltransferase activity

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 ALG8 ST3GAL4 UGT2B28 HAS2 UGT2B11

9.57e-182886117GO:0016757
GeneOntologyMolecularFunctionmonocarboxylic acid binding

UGT1A4 UGT1A1 UGT1A3 ACACB UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

4.16e-161076112GO:0033293
GeneOntologyMolecularFunctioncarboxylic acid binding

UGT1A4 UGT1A1 UGT1A3 ACACB UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

6.81e-122396112GO:0031406
GeneOntologyMolecularFunctionorganic acid binding

UGT1A4 UGT1A1 UGT1A3 ACACB UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

1.39e-112546112GO:0043177
GeneOntologyMolecularFunctionprotein heterodimerization activity

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

3.15e-06398619GO:0046982
GeneOntologyMolecularFunctionpalmitoleoyltransferase activity

PORCN CPT1A

9.18e-062612GO:1990698
GeneOntologyMolecularFunctionlipid binding

UGT1A4 UGT1A1 UGT1A3 SNX14 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

3.71e-059886112GO:0008289
GeneOntologyMolecularFunctionprotein kinase C binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.93e-0566614GO:0005080
GeneOntologyMolecularFunctionsteroid binding

UGT1A1 UGT1A10 UGT1A8 UGT1A7 UGT1A9

5.36e-05133615GO:0005496
GeneOntologyMolecularFunctionfatty acid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9

5.87e-0569614GO:0005504
GeneOntologyMolecularFunctionprotein homodimerization activity

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

7.76e-04815619GO:0042803
GeneOntologyMolecularFunctionfloppase activity

ABCA2 ATP8A2

1.07e-0316612GO:0140328
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA2 ATP8A2

3.30e-0328612GO:0140326
GeneOntologyMolecularFunctionenzyme regulator activity

UGT1A1 ABCA2 PIK3CA UGT1A10 UGT1A8 UGT1A7 TBCK UGT1A9 SGSM3 SIPA1L2 PRDM14

3.46e-0314186111GO:0030234
GeneOntologyBiologicalProcesscellular glucuronidation

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

8.95e-32216114GO:0052695
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

7.36e-30266114GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

7.36e-30266114GO:0006063
GeneOntologyBiologicalProcessxenobiotic glucuronidation

UGT1A1 UGT1A3 UGT1A8 UGT1A7 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

1.55e-24126110GO:0052697
GeneOntologyBiologicalProcessestrogen metabolic process

UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

3.21e-18526111GO:0008210
GeneOntologyBiologicalProcessxenobiotic metabolic process

UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT2B4 UGT2B7 UGT2B10 UGT1A9 SLC28A3 UGT2B28 UGT2B11

2.01e-161416113GO:0006805
GeneOntologyBiologicalProcessbiphenyl catabolic process

UGT1A1 UGT2B4 UGT2B7 UGT2B10 UGT2B28 UGT2B11

1.45e-148616GO:0070980
GeneOntologyBiologicalProcesscellular response to xenobiotic stimulus

UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT2B4 UGT2B7 UGT2B10 UGT1A9 SLC28A3 UGT2B28 UGT2B11

7.61e-142226113GO:0071466
GeneOntologyBiologicalProcessbiphenyl metabolic process

UGT1A1 UGT2B4 UGT2B7 UGT2B10 UGT2B28 UGT2B11

1.08e-1310616GO:0018879
GeneOntologyBiologicalProcessresponse to xenobiotic stimulus

UGT1A1 UGT1A3 SCN11A ABCA2 ACACB UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT2B4 UGT2B7 UGT2B10 UGT1A9 SLC28A3 UGT2B28 CPT1A UGT2B11

1.17e-135256117GO:0009410
GeneOntologyBiologicalProcessflavonoid glucuronidation

UGT1A1 UGT1A3 UGT1A8 UGT1A7 UGT1A9

1.91e-135615GO:0052696
GeneOntologyBiologicalProcessflavonoid metabolic process

UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A9

8.77e-1313616GO:0009812
GeneOntologyBiologicalProcessflavone metabolic process

UGT1A1 UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.15e-126615GO:0051552
GeneOntologyBiologicalProcessbenzene-containing compound metabolic process

UGT1A1 UGT1A6 UGT2B4 UGT2B7 UGT2B10 UGT2B28 UGT2B11

1.33e-1137617GO:0042537
GeneOntologyBiologicalProcessmonocarboxylic acid metabolic process

UGT1A4 UGT1A1 UGT1A3 ACACB UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 CPT1A ADTRP UGT2B11

2.28e-117316117GO:0032787
GeneOntologyBiologicalProcesssteroid metabolic process

UGT1A4 UGT1A1 UGT1A3 ABCA2 UGT1A10 UGT1A8 UGT1A7 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

5.95e-113766113GO:0008202
GeneOntologyBiologicalProcessestrogen catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.45e-105614GO:0006711
GeneOntologyBiologicalProcesshormone metabolic process

UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

6.80e-102866111GO:0042445
GeneOntologyBiologicalProcessphenylpropanoid catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.03e-096614GO:0046271
GeneOntologyBiologicalProcesscoumarin catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.03e-096614GO:0046226
GeneOntologyBiologicalProcessxenobiotic catabolic process

UGT1A1 UGT2B4 UGT2B7 UGT2B10 UGT2B28 UGT2B11

1.13e-0937616GO:0042178
GeneOntologyBiologicalProcesscarboxylic acid metabolic process

UGT1A4 UGT1A1 UGT1A3 ACACB UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 CPT1A ADTRP UGT2B11

4.72e-0910356117GO:0019752
GeneOntologyBiologicalProcessoxoacid metabolic process

UGT1A4 UGT1A1 UGT1A3 ACACB UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 CPT1A ADTRP UGT2B11

6.55e-0910586117GO:0043436
GeneOntologyBiologicalProcessorganic acid metabolic process

UGT1A4 UGT1A1 UGT1A3 ACACB UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 CPT1A ADTRP UGT2B11

7.13e-0910646117GO:0006082
GeneOntologyBiologicalProcessphenylpropanoid metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.43e-0810614GO:0009698
GeneOntologyBiologicalProcesscoumarin metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.43e-0810614GO:0009804
GeneOntologyBiologicalProcessandrogen metabolic process

UGT2B4 UGT2B7 UGT2B10 UGT2B28 UGT2B11

8.91e-0838615GO:0008209
GeneOntologyBiologicalProcessretinoic acid metabolic process

UGT1A1 UGT1A3 UGT1A8 UGT1A7 UGT1A9

1.16e-0740615GO:0042573
GeneOntologyBiologicalProcesspigment metabolic process

UGT1A4 UGT1A1 UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.46e-0794616GO:0042440
GeneOntologyBiologicalProcesshormone catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.99e-0721614GO:0042447
GeneOntologyBiologicalProcessregulation of hormone levels

UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 CPT1A UGT2B11

6.31e-076846112GO:0010817
GeneOntologyBiologicalProcesssecondary metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9 CPT1A

1.61e-0667615GO:0019748
GeneOntologyBiologicalProcessliver development

UGT1A1 PIK3CA UGT1A10 UGT1A8 UGT1A7 UGT1A9 CPT1A

2.17e-06202617GO:0001889
GeneOntologyBiologicalProcesshepaticobiliary system development

UGT1A1 PIK3CA UGT1A10 UGT1A8 UGT1A7 UGT1A9 CPT1A

2.39e-06205617GO:0061008
GeneOntologyBiologicalProcesssteroid catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.00e-0634614GO:0006706
GeneOntologyBiologicalProcessisoprenoid metabolic process

UGT1A1 UGT1A3 UGT1A8 UGT1A7 UGT1A9 ALG8

4.22e-06144616GO:0006720
GeneOntologyBiologicalProcessretinoid metabolic process

UGT1A1 UGT1A3 UGT1A8 UGT1A7 UGT1A9

6.57e-0689615GO:0001523
GeneOntologyBiologicalProcessditerpenoid metabolic process

UGT1A1 UGT1A3 UGT1A8 UGT1A7 UGT1A9

8.59e-0694615GO:0016101
GeneOntologyBiologicalProcessbilirubin conjugation

UGT1A4 UGT1A1

8.60e-062612GO:0006789
GeneOntologyBiologicalProcessterpenoid metabolic process

UGT1A1 UGT1A3 UGT1A8 UGT1A7 UGT1A9

1.47e-05105615GO:0006721
GeneOntologyBiologicalProcesscellular catabolic process

UGT1A1 SNX14 ABCA2 ACACB PIK3CA UGT2B4 UGT2B7 UGT2B10 RNF213 UGT2B28 CPT1A ADTRP UGT2B11

6.14e-0512536113GO:0044248
GeneOntologyBiologicalProcesslipid catabolic process

ACACB UGT1A10 UGT1A8 UGT1A7 UGT1A9 CPT1A ADTRP

1.31e-04382617GO:0016042
GeneOntologyBiologicalProcessnegative regulation of steroid metabolic process

UGT1A1 ABCA2 UGT1A8

1.64e-0436613GO:0045939
GeneOntologyBiologicalProcesslipid storage

ACACB CDS2 RNF213 CPT1A

2.65e-04105614GO:0019915
GeneOntologyBiologicalProcessvitamin D3 metabolic process

UGT1A4 UGT1A3

3.06e-049612GO:0070640
GeneOntologyBiologicalProcesslipid modification

ACACB PORCN RNF213 ST3GAL4 CPT1A

4.26e-04214615GO:0030258
GeneOntologyBiologicalProcesseating behavior

NPY5R ATP8A2 CPT1A

6.10e-0456613GO:0042755
GeneOntologyBiologicalProcessporphyrin-containing compound catabolic process

UGT1A4 UGT1A1

6.57e-0413612GO:0006787
GeneOntologyBiologicalProcesstetrapyrrole catabolic process

UGT1A4 UGT1A1

7.65e-0414612GO:0033015
GeneOntologyBiologicalProcesslipid droplet formation

CDS2 RNF213

8.81e-0415612GO:0140042
GeneOntologyBiologicalProcessnegative regulation of lipid metabolic process

UGT1A1 ABCA2 ACACB UGT1A8

8.96e-04145614GO:0045833
GeneOntologyBiologicalProcessgland development

UGT1A1 PIK3CA UGT1A10 UGT1A8 UGT1A7 UGT1A9 CPT1A

1.26e-03558617GO:0048732
GeneOntologyBiologicalProcessceramide transport

ABCA2 ABCA13

1.28e-0318612GO:0035627
GeneOntologyBiologicalProcesslipid localization

ABCA2 ACACB ABCA13 ATP8A2 CDS2 RNF213 CPT1A

1.35e-03565617GO:0010876
GeneOntologyBiologicalProcessregulation of lipid metabolic process

UGT1A1 ABCA2 ACACB UGT1A8 RNF213 CPT1A

1.40e-03415616GO:0019216
GeneOntologyCellularComponentendoplasmic reticulum membrane

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 CDS2 UGT2B4 UGT2B7 UGT2B10 PORCN UGT1A9 ALG8 SLC28A3 FLRT2 UGT2B28 HAS2 PLD3 UGT2B11

3.97e-1112936121GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 CDS2 UGT2B4 UGT2B7 UGT2B10 PORCN UGT1A9 ALG8 SLC28A3 FLRT2 UGT2B28 HAS2 PLD3 UGT2B11

4.33e-1112996121GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 CDS2 UGT2B4 UGT2B7 UGT2B10 PORCN UGT1A9 ALG8 SLC28A3 FLRT2 UGT2B28 HAS2 PLD3 UGT2B11

6.44e-1113276121GO:0042175
GeneOntologyCellularComponentnuclear outer membrane

UGT2B4 UGT2B7 UGT2B10 UGT2B28 UGT2B11

1.09e-0740615GO:0005640
GeneOntologyCellularComponentorganelle outer membrane

ACACB UGT2B4 UGT2B7 UGT2B10 UGT2B28 CPT1A UGT2B11

1.65e-05279617GO:0031968
GeneOntologyCellularComponentouter membrane

ACACB UGT2B4 UGT2B7 UGT2B10 UGT2B28 CPT1A UGT2B11

1.73e-05281617GO:0019867
DomainUDPGT

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

2.77e-31216014PF00201
DomainUDPGT

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

2.77e-31216014PS00375
DomainUDP_glucos_trans

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

2.77e-31216014IPR002213
PathwayREACTOME_GLUCURONIDATION

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

4.02e-29255114M17787
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

4.02e-29255114M605
PathwayWP_GLUCURONIDATION

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

8.69e-29265114M39404
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

3.59e-28285114M19580
PathwayREACTOME_GLUCURONIDATION

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

8.34e-27245113MM14599
PathwayWP_GLUCURONIDATION

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

1.73e-26255113MM15820
PathwayKEGG_STARCH_AND_SUCROSE_METABOLISM

UGT1A4 UGT1A1 UGT1A3 GANC UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

9.98e-26525115M14171
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

3.06e-25415114M7399
PathwayKEGG_DRUG_METABOLISM_OTHER_ENZYMES

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

1.09e-23515114M17726
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

3.65e-23555114M14933
PathwayREACTOME_ASPIRIN_ADME

UGT1A4 UGT1A1 UGT1A3 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

1.65e-22445113M45014
PathwayREACTOME_ASPIRIN_ADME

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

2.31e-22455113MM15694
PathwayKEGG_RETINOL_METABOLISM

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

3.92e-22645114M9488
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

1.56e-21705114M16794
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

2.40e-21725114M9257
PathwayREACTOME_DRUG_ADME

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 SLC28A3 UGT2B28 UGT2B11

1.97e-201095115M45012
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

1.18e-181095114M18788
PathwayREACTOME_DRUG_ADME

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 SLC28A3 UGT2B28 UGT2B11

4.23e-181195114MM15692
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

4.91e-171075113MM14595
PathwayREACTOME_PARACETAMOL_ADME

UGT1A1 UGT1A10 UGT1A8 UGT1A7 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

8.84e-17395110MM15695
PathwayREACTOME_PREDNISONE_ADME

UGT1A4 UGT1A3 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT2B28 UGT2B11

7.76e-1523518MM16639
PathwayWP_CODEINE_AND_MORPHINE_METABOLISM

UGT1A1 UGT1A10 UGT1A8 UGT1A6 UGT2B4 UGT2B7 UGT1A9

1.78e-1414517M39328
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

2.61e-142205114M10320
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

6.08e-132195113MM14838
PathwayWP_ESTROGEN_METABOLISM

UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A5 UGT1A9

8.65e-1322517MM15888
PathwayWP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9 UGT2B28 UGT2B11

1.63e-121835112M39588
PathwayWP_ESTROGEN_METABOLISM_WP697

UGT1A1 UGT1A3 UGT1A6 UGT2B7 UGT1A9

4.19e-0918515M39424
PathwayWP_METAPATHWAY_BIOTRANSFORMATION

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A5 UGT1A9

6.87e-08153518MM15844
PathwayWP_ARYL_HYDROCARBON_RECEPTOR_PATHWAY_WP2873

UGT1A4 UGT1A1 UGT1A7 UGT1A6 UGT1A9

5.55e-0745515M39615
PathwayREACTOME_HEME_DEGRADATION

UGT1A4 UGT1A1 UGT1A3 UGT1A5

7.05e-0720514MM14721
PathwayWP_2Q37_COPY_NUMBER_VARIATION_SYNDROME

UGT1A4 UGT1A1 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A9

8.35e-07145517M45512
PathwayWP_TAMOXIFEN_METABOLISM

UGT1A4 UGT1A10 UGT1A8 UGT2B7

8.69e-0721514M39631
PathwayREACTOME_PARACETAMOL_ADME

UGT1A1 UGT1A10 UGT1A6 UGT1A9

3.38e-0629514M45015
PathwayWP_CONSTITUTIVE_ANDROSTANE_RECEPTOR_PATHWAY

UGT1A4 UGT1A1 UGT1A6 UGT1A9

4.45e-0631514M39476
PathwayWP_PREGNANE_X_RECEPTOR_PATHWAY

UGT1A4 UGT1A1 UGT1A6 UGT1A9

5.07e-0632514M39567
PathwayREACTOME_METABOLISM_OF_PORPHYRINS

UGT1A4 UGT1A1 UGT1A3 UGT1A5

5.07e-0632514MM14719
PathwayWP_IRINOTECAN_PATHWAY

UGT1A1 UGT1A10 UGT1A9

9.59e-0612513M39611
PathwayWP_NRF2_PATHWAY

UGT1A4 UGT1A1 UGT1A7 UGT1A6 UGT2B7 UGT1A9

1.12e-05141516M39454
PathwayWP_NUCLEAR_RECEPTORS_METAPATHWAY

UGT1A4 UGT1A1 UGT1A7 UGT1A6 UGT2B4 UGT2B7 UGT1A9 CPT1A

1.53e-05314518M39428
PathwayREACTOME_ATORVASTATIN_ADME

UGT1A4 UGT1A3 UGT1A5

1.97e-0515513MM15697
PathwayWP_ESTROGEN_METABOLISM_WP5276

UGT1A10 UGT1A8 UGT2B7

8.56e-0524513M46445
PathwayWP_ARYLAMINE_METABOLISM

UGT1A4 UGT1A9

1.91e-046512M39437
PathwayWP_NICOTINE_METABOLISM_IN_LIVER_CELLS

UGT1A4 UGT1A9

1.91e-046512M39600
PathwayREACTOME_SYNTHESIS_OF_PG

CDS2 PLD3

3.54e-048512M26961
PathwayREACTOME_PREDNISONE_ADME

UGT1A3 UGT2B7

5.67e-0410512M46430
PathwayWP_MINERALOCORTICOID_BIOSYNTHESIS

UGT1A10 UGT2B7

1.14e-0314512M46453
PathwayREACTOME_CARNITINE_METABOLISM

ACACB CPT1A

1.14e-0314512M27098
PathwayREACTOME_CARNITINE_METABOLISM

ACACB CPT1A

1.14e-0314512MM14788
PathwayREACTOME_HEME_DEGRADATION

UGT1A4 UGT1A1

1.31e-0315512M27060
PathwayWP_AMPACTIVATED_PROTEIN_KINASE_SIGNALING

ACACB PIK3CA CPT1A

1.82e-0367513M39630
PathwayBIOCARTA_RAC1_PATHWAY

LIMK1 PIK3CA

2.58e-0321512M8601
PathwayBIOCARTA_RAC1_PATHWAY

LIMK1 PIK3CA

2.58e-0321512MM1463
PathwayPID_HEDGEHOG_2PATHWAY

PIK3CA PTCH2

2.83e-0322512M211
PathwayREACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING

PIK3CA MAP3K8

2.83e-0322512M13897
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT2B4 UGT2B7 UGT1A9

8.33e-2712611020308471
Pubmed

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

8.46e-26961922511988
Pubmed

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT1A9

1.26e-251461109295054
Pubmed

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

8.45e-251061923642732
Pubmed

UDP-glucuronosyltransferases.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

8.45e-251061911465080
Pubmed

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

8.45e-251061923371916
Pubmed

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

8.45e-251061922558097
Pubmed

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9 UGT2B28 UGT2B11

7.19e-2466611319898482
Pubmed

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.85e-231261919419973
Pubmed

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.85e-231261911434514
Pubmed

Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A9

5.55e-23861817179145
Pubmed

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A9

5.55e-23861820610558
Pubmed

Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms.

UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT2B4 UGT2B7 UGT1A9

5.55e-23861818052087
Pubmed

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

6.02e-231361922085899
Pubmed

Genome-wide analysis of hepatic lipid content in extreme obesity.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

6.02e-231361925246029
Pubmed

Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.68e-221461921646302
Pubmed

Human UDP-glucuronosyltransferases: metabolism, expression, and disease.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.68e-221461910836148
Pubmed

Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.68e-221461914672974
Pubmed

Genome-wide association meta-analysis for total serum bilirubin levels.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

9.59e-221661919414484
Pubmed

Genome-wide association of serum bilirubin levels in Korean population.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

2.03e-211761920639394
Pubmed

A genome-wide assessment of variability in human serum metabolism.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

7.71e-211961923281178
Pubmed

Assignment of the human UDP glucuronosyltransferase gene (UGT1A1) to chromosome region 2q37.

UGT1A4 UGT1A1 UGT1A10 UGT1A8 UGT1A7 UGT1A5 UGT1A9

3.57e-2076178467709
Pubmed

Molecular cloning of two cDNAs encoding the mouse bilirubin/phenol family of UDP-glucuronosyltransferases (mUGTBr/p).

UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A5 UGT1A9

3.57e-2076178464825
Pubmed

Genetic determinants influencing human serum metabolome among African Americans.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.08e-192461924625756
Pubmed

A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.

UGT1A4 UGT1A1 UGT1A3 UGT1A8 UGT1A6 UGT1A5 UGT1A9

1.28e-1896171339448
Pubmed

Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.

UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT2B4 UGT2B7 UGT1A9

2.40e-181861820056724
Pubmed

Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population.

UGT1A4 UGT1A1 UGT1A3 UGT1A7 UGT1A6 UGT1A9

2.26e-17661619204906
Pubmed

Use of glucuronidation fingerprinting to describe and predict mono- and dihydroxyflavone metabolism by recombinant UGT isoforms and human intestinal and liver microsomes.

UGT1A1 UGT1A10 UGT1A8 UGT1A7 UGT2B7 UGT1A9

2.26e-17661620297805
Pubmed

Detoxification enzyme polymorphisms are not involved in duodenal adenomatosis in familial adenomatous polyposis.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A6 UGT2B4 UGT2B7

2.81e-171261718161889
Pubmed

Involvement of human UGT2B7 and 2B15 in rofecoxib metabolism.

UGT1A4 UGT1A1 UGT1A3 UGT1A8 UGT2B7 UGT1A9

6.31e-16861612695355
Pubmed

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.

UGT1A1 UGT2B4 UGT2B7 UGT2B10 UGT2B28 UGT2B11

6.31e-16861632093886
Pubmed

Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry.

UGT1A4 UGT1A1 UGT1A3 UGT1A6 UGT2B7 UGT1A9

6.31e-16861622579593
Pubmed

Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine.

UGT1A1 UGT1A3 UGT1A10 UGT2B4 UGT2B7 UGT2B10

6.31e-16861610748067
Pubmed

Human metabolic individuality in biomedical and pharmaceutical research.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

7.14e-165761921886157
Pubmed

Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A9

1.40e-14561515057901
Pubmed

Weak activity of UDP-glucuronosyltransferase toward Bisphenol analogs in mouse perinatal development.

UGT2B4 UGT2B7 UGT2B10 UGT2B28 UGT2B11

2.94e-13761526074487
Pubmed

The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.

UGT1A1 UGT1A3 UGT1A7 UGT2B4 UGT2B7

7.83e-13861518719240
Pubmed

Discovery and refinement of loci associated with lipid levels.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9 ST3GAL4

3.76e-12211611024097068
Pubmed

Influence of drug transporters and UGT polymorphisms on pharmacokinetics of phenolic glucuronide metabolite of mycophenolic acid in Japanese renal transplant recipients.

UGT1A1 UGT1A8 UGT1A7 UGT1A6 UGT1A9

6.43e-121161518695635
Pubmed

Mechanisms of inherited deficiencies of multiple UDP-glucuronosyltransferase isoforms in two patients with Crigler-Najjar syndrome, type I.

UGT1A4 UGT1A1 UGT1A6 UGT1A9

8.56e-1246141634050
Pubmed

Genetic variations and haplotypes of UDP-glucuronosyltransferase 1A locus in a Korean population.

UGT1A4 UGT1A1 UGT1A7 UGT1A5

8.56e-12461418223459
Pubmed

Cloning of two human liver bilirubin UDP-glucuronosyltransferase cDNAs with expression in COS-1 cells.

UGT1A4 UGT1A1 UGT1A6 UGT1A9

8.56e-1246141898728
Pubmed

Urinary excretion of phenytoin metabolites, 5-(4'-hydroxyphenyl)-5-phenylhydantoin and its O-glucuronide in humans and analysis of genetic polymorphisms of UDP-glucuronosyltransferases.

UGT1A4 UGT1A1 UGT1A6 UGT1A9

8.56e-12461415855726
Pubmed

Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8.

UGT1A4 UGT1A1 UGT1A3 UGT1A8

8.56e-1246149535849
Pubmed

Identification of an A-to-G missense mutation in exon 2 of the UGT1 gene complex that causes Crigler-Najjar syndrome type 2.

UGT1A4 UGT1A1 UGT1A6 UGT1A9

8.56e-1246148276413
Pubmed

Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue.

UGT1A4 UGT1A3 UGT1A10 UGT1A7

8.56e-1246149271343
Pubmed

Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1*6 and *28.

UGT1A1 UGT1A10 UGT1A7 UGT1A9

8.56e-12461417558305
Pubmed

Chromosomal mapping of a human phenol UDP-glucuronosyltransferase, GNT1.

UGT1A1 UGT1A10 UGT1A6 UGT1A9

8.56e-1246142108603
Pubmed

Identification of defect in the genes for bilirubin UDP-glucuronosyl-transferase in a patient with Crigler-Najjar syndrome type II.

UGT1A4 UGT1A1 UGT1A6 UGT1A9

8.56e-1246148280139
Pubmed

Pharmacokinetics of mycophenolate mofetil and its glucuronide metabolites in healthy volunteers.

UGT1A1 UGT1A7 UGT2B7 UGT1A9

4.28e-11561418597651
Pubmed

Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients.

UGT1A4 UGT1A1 UGT2B7 UGT1A9

4.28e-11561426010150
Pubmed

Risk of diarrhoea in a long-term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8 2 variant allele.

UGT1A8 UGT1A7 UGT2B7 UGT1A9

4.28e-11561420565459
Pubmed

An atlas of genetic influences on human blood metabolites.

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

4.86e-1119061924816252
Pubmed

Circadian Clock Component Rev-erbα Regulates Diurnal Rhythm of UDP-Glucuronosyltransferase 1a9 and Drug Glucuronidation in Mice.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.28e-10661432527940
Pubmed

Cyp3a11-mediated testosterone-6β-hydroxylation decreased, while UGT1a9-mediated propofol O-glucuronidation increased, in mice with diabetes mellitus.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.98e-10761427514509
Pubmed

Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk.

UGT1A1 UGT1A8 UGT1A7 UGT1A6

5.96e-10861415319294
Pubmed

Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.

UGT1A1 UGT1A3 UGT2B4 UGT2B7

5.96e-10861420142249
Pubmed

Functional polymorphisms of UDP-glucuronosyltransferases 1A1, 1A6 and 1A8 are not involved in chronic pancreatitis.

UGT1A1 UGT1A8 UGT1A6

5.13e-09361315247627
Pubmed

Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan.

UGT1A1 UGT1A7 UGT1A9

5.13e-09361319364970
Pubmed

Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4α Is Mediated by a Novel Composite Regulatory Element.

UGT1A10 UGT1A8 UGT1A9

5.13e-09361329519853
Pubmed

Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin.

UGT1A1 UGT1A7 UGT1A9

5.13e-09361316636344
Pubmed

Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases.

UGT1A10 UGT1A6 UGT1A9

5.13e-09361320007669
Pubmed

Functional significance of UDP-glucuronosyltransferase variants in the metabolism of active tamoxifen metabolites.

UGT1A10 UGT1A8 UGT2B7

5.13e-09361319244109
Pubmed

Glucuronidation of the nonsteroidal antiestrogen EM-652 (SCH 57068), by human and monkey steroid conjugating UDP-glucuronosyltransferase enzymes.

UGT1A1 UGT1A3 UGT1A8

5.13e-09361311179460
Pubmed

Glucuronidation of icaritin by human liver microsomes, human intestine microsomes and expressed UDP-glucuronosyltransferase enzymes: identification of UGT1A3, 1A9 and 2B7 as the main contributing enzymes.

UGT1A3 UGT2B7 UGT1A9

5.13e-09361328443723
Pubmed

Raloxifene glucuronidation in liver and intestinal microsomes of humans and monkeys: contribution of UGT1A1, UGT1A8 and UGT1A9.

UGT1A1 UGT1A8 UGT1A9

5.13e-09361326247833
Pubmed

cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily.

UGT2B4 UGT2B10 UGT2B11

5.13e-0936138333863
Pubmed

Isolation and characterization of a UDP-glucuronosyltransferase (UGT1A01) cloned from female rhesus monkey.

UGT1A1 UGT1A3 UGT1A5

5.13e-09361312051676
Pubmed

Frequent co-occurrence of the TATA box mutation associated with Gilbert's syndrome (UGT1A1*28) with other polymorphisms of the UDP-glucuronosyltransferase-1 locus (UGT1A6*2 and UGT1A7*3) in Caucasians and Egyptians.

UGT1A1 UGT1A7 UGT1A6

5.13e-09361312732365
Pubmed

The impact of UGT1A8, UGT1A9, and UGT2B7 genetic polymorphisms on the pharmacokinetic profile of mycophenolic acid after a single oral dose in healthy volunteers.

UGT1A8 UGT2B7 UGT1A9

5.13e-09361317339869
Pubmed

Inter-isoform Hetero-dimerization of Human UDP-Glucuronosyltransferases (UGTs) 1A1, 1A9, and 2B7 and Impacts on Glucuronidation Activity.

UGT1A1 UGT2B7 UGT1A9

5.13e-09361327857056
Pubmed

Differences in UGT1A1, UGT1A7, and UGT1A9 polymorphisms between Uzbek and Japanese populations.

UGT1A1 UGT1A7 UGT1A9

5.13e-09361324453052
Pubmed

Phase II study of a triplet regimen of S-1 combined with irinotecan and oxaliplatin in patients with metastatic gastric cancer: clinical and pharmacogenetic results.

UGT1A1 UGT1A7 UGT1A6

5.13e-09361320860988
Pubmed

UGT genotype may contribute to adverse events following medication with mycophenolate mofetil in pediatric kidney transplant recipients.

UGT1A8 UGT2B7 UGT1A9

5.13e-09361319225446
Pubmed

UGT1A1, UGT1A6 and UGT1A7 genetic analysis: repercussion for irinotecan pharmacogenetics in the São Miguel Island Population (Azores, Portugal).

UGT1A1 UGT1A7 UGT1A6

5.13e-09361319712005
Pubmed

[Influence of genetic polymorphisms in UGT1A1, UGT1A7 and UGT1A9 on the pharmacokynetics of irinotecan, SN-38 and SN-38G].

UGT1A1 UGT1A7 UGT1A9

5.13e-09361323789755
Pubmed

Glucuronidation of catechols by human hepatic, gastric, and intestinal microsomal UDP-glucuronosyltransferases (UGT) and recombinant UGT1A6, UGT1A9, and UGT2B7.

UGT1A6 UGT2B7 UGT1A9

5.13e-09361312623074
Pubmed

Genetic linkage of UGT1A7 and UGT1A9 polymorphisms to UGT1A1*6 is associated with reduced activity for SN-38 in Japanese patients with cancer.

UGT1A1 UGT1A7 UGT1A9

5.13e-09361317406868
Pubmed

Modulation of the human glucuronosyltransferase UGT1A pathway by splice isoform polypeptides is mediated through protein-protein interactions.

UGT1A1 UGT1A8 UGT1A7

5.13e-09361319996319
Pubmed

Significance of UGT1A6, UGT1A9, and UGT2B7 genetic variants and their mRNA expression in the clinical outcome of renal cell carcinoma.

UGT1A6 UGT2B7 UGT1A9

5.13e-09361336571650
Pubmed

Gilbert's syndrome and hyperbilirubinemia in protease inhibitor therapy--an extended haplotype of genetic variants increases risk in indinavir treatment.

UGT1A1 UGT1A3 UGT1A7

5.13e-09361319303655
Pubmed

Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone.

UGT1A8 UGT2B7 UGT1A9

5.13e-09361316397224
Pubmed

Cloning and characterization of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 gene promoters: differential regulation through an interior-like region.

UGT1A10 UGT1A8 UGT1A9

5.13e-09361312847094
Pubmed

High enzyme activity UGT1A1 or low activity UGT1A8 and UGT2B4 genotypes increase esophageal cancer risk.

UGT1A1 UGT1A8 UGT2B4

5.13e-09361322367021
Pubmed

Linkage disequilibrium of UGT1A1 *6 and UGT1A1 *28 in relation to UGT1A6 and UGT1A7 polymorphisms.

UGT1A1 UGT1A7 UGT1A6

5.13e-09361316969497
Pubmed

Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho-glucuronosyltransferases expressed in endometrium.

UGT1A1 UGT1A8 UGT2B7

5.13e-09361315472229
Pubmed

Human UDP-glucuronosyltransferase (UGT) 2B10 in drug N-glucuronidation: substrate screening and comparison with UGT1A3 and UGT1A4.

UGT1A4 UGT1A3 UGT2B10

5.13e-09361323611809
Pubmed

Alteration of the function of the UDP-glucuronosyltransferase 1A subfamily by cytochrome P450 3A4: different susceptibility for UGT isoforms and UGT1A1/7 variants.

UGT1A1 UGT1A7 UGT1A6

2.05e-08461324255116
Pubmed

Influence of uridine diphosphate (UDP)-glucuronosyltransferases and ABCC2 genetic polymorphisms on the pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant recipients.

UGT1A8 UGT2B7 UGT1A9

2.05e-08461318946804
Pubmed

Hepatocyte nuclear factor-1 alpha is associated with UGT1A1, UGT1A9 and UGT2B7 mRNA expression in human liver.

UGT1A1 UGT2B7 UGT1A9

2.05e-08461317440429
Pubmed

Population pharmacokinetics and pharmacogenetics of mycophenolic acid following administration of mycophenolate mofetil in de novo pediatric renal-transplant patients.

UGT1A8 UGT2B7 UGT1A9

2.05e-08461320147615
Pubmed

Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus.

UGT1A10 UGT2B7 UGT2B10

2.05e-08461310024527
Pubmed

UGT1A and TYMS genetic variants predict toxicity and response of colorectal cancer patients treated with first-line irinotecan and fluorouracil combination therapy.

UGT1A1 UGT1A7 UGT1A9

2.05e-08461320628391
Pubmed

Coimmunoprecipitation of UDP-glucuronosyltransferase isoforms and cytochrome P450 3A4.

UGT1A1 UGT1A6 UGT2B7

2.05e-08461315486048
Pubmed

Contribution of polymorphisms in UDP-glucuronosyltransferase and CYP2D6 to the individual variation in disposition of carvedilol.

UGT1A1 UGT2B4 UGT2B7

2.05e-08461316849011
Pubmed

Genetic polymorphisms of UGT1A8, UGT1A9, UGT2B7 and ABCC2 in Chinese renal transplant recipients and a comparison with other ethnic populations.

UGT1A8 UGT2B7 UGT1A9

2.05e-08461323700788
Pubmed

UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients.

UGT1A1 UGT2B4 UGT2B7

5.12e-08561315318931
Pubmed

Isolation of cDNAs for mouse phenol and bilirubin UDP-glucuronosyltransferases and mapping of the mouse gene for phenol UDP-glucuronosyltransferase (Ugtla1) to chromosome 1 by restriction fragment length variations.

UGT1A1 UGT1A3 UGT1A5

5.12e-0856137677729
Pubmed

Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.

UGT1A10 UGT1A8 UGT1A9

4.28e-07961320732626
Pubmed

Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer.

UGT1A1 UGT2B4 UGT1A9 UGT2B11

6.04e-073861420214802
InteractionUGT2B28 interactions

UGT2B10 UGT2B28 UGT2B11

4.74e-076593int:UGT2B28
InteractionUGT1A9 interactions

UGT1A10 UGT1A7 UGT1A9

6.68e-0613593int:UGT1A9
InteractionCYP3A4 interactions

UGT1A1 UGT1A6 UGT2B7

1.57e-0517593int:CYP3A4
InteractionUGT1A7 interactions

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.33e-0557594int:UGT1A7
InteractionUGT1A8 interactions

UGT1A8 UGT1A7

2.52e-053592int:UGT1A8
InteractionUGT1A3 interactions

UGT1A3 UGT1A5

8.38e-055592int:UGT1A3
InteractionUGT2B10 interactions

UGT2B10 UGT2B28

8.38e-055592int:UGT2B10
InteractionUGT1A10 interactions

UGT1A10 UGT1A7 UGT1A9

1.22e-0433593int:UGT1A10
InteractionUGT2B11 interactions

UGT2B28 UGT2B11

1.75e-047592int:UGT2B11
Cytoband2q37

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.37e-19316192q37
CytobandEnsembl 112 genes in cytogenetic band chr2q37

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

2.01e-11226619chr2q37
CytobandEnsembl 112 genes in cytogenetic band chr4q13

UGT2B4 UGT2B7 UGT2B10 UGT2B28 UGT2B11

2.24e-06157615chr4q13
Cytoband4q13.2

UGT2B10 UGT2B28 UGT2B11

9.77e-06316134q13.2
Cytoband4q13

UGT2B4 UGT2B7

1.80e-04156124q13
GeneFamilyUDP glucuronosyltransferases

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

3.43e-29324714363
GeneFamilyATP binding cassette subfamily A

ABCA2 ABCA13

5.90e-0414472805
CoexpressionWENG_POR_TARGETS_LIVER_UP

UGT2B4 UGT2B7 UGT2B10 UGT2B28 UGT2B11

1.40e-0753605MM1203
CoexpressionSERVITJA_ISLET_HNF1A_TARGETS_DN

UGT1A1 UGT2B4 UGT2B7 UGT2B10 UGT2B28 UGT2B11

3.49e-07121606MM935
CoexpressionNFE2L2.V2

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.15e-06469609M2870
CoexpressionWAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_36HR

GANC UGT1A10 UGT1A8 UGT1A7 UGT1A9 CPT1A

1.44e-06154606MM1313
CoexpressionVANLOO_SP3_TARGETS_DN

UGT2B4 UGT2B7 UGT2B10 UGT2B28 UGT2B11

3.91e-06103605MM919
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4

UGT2B4 UGT2B7 UGT2B10 UGT2B28 ADTRP UGT2B11 ZNF865

1.03e-05330607MM1120
CoexpressionSERVITJA_LIVER_HNF1A_TARGETS_DN

UGT2B4 UGT2B7 UGT2B10 UGT2B28 UGT2B11

7.51e-05190605MM1311
CoexpressionOHGUCHI_LIVER_HNF4A_TARGETS_DN

UGT2B4 UGT2B7 UGT2B10 UGT2B28 UGT2B11

9.78e-05201605MM1294
CoexpressionAtlasliver

UGT1A4 UGT1A1 UGT1A3 UGT1A6 UGT2B4 UGT2B7 UGT2B10 UGT1A9

1.98e-05419598liver
ToppCellmLN-(0)_NK_cell-(00)_NK|mLN / shred on region, Cell_type, and subtype

EOMES ABCA2 MAP3K8 ANKRD28 ST3GAL4

7.83e-0619961559d8e4f57580c7273308c32e5308fc1d704b1f6d
ToppCellmLN-NK_cell-NK|mLN / Region, Cell class and subclass

EOMES ABCA2 MAP3K8 ANKRD28 ST3GAL4

7.83e-06199615cc9836b8d18edabe8849a3e948b84d954ef68c48
ToppCellmLN-(0)_NK_cell|mLN / shred on region, Cell_type, and subtype

EOMES ABCA2 MAP3K8 ANKRD28 ST3GAL4

7.83e-0619961505f5ae4c049f242131a7f59bcce4b18ed52f11be
ToppCellmLN-NK_cell|mLN / Region, Cell class and subclass

EOMES ABCA2 MAP3K8 ANKRD28 ST3GAL4

7.83e-06199615dcc1d9a3f6f0e64f111d18386bfe5b154e9d5bbe
ComputationalGenes in the cancer module 227.

UGT1A6 UGT2B4 UGT2B7

1.28e-0515343MODULE_227
ComputationalSteroid hormone and heme metabolism.

UGT2B4 UGT2B7 UGT2B10

1.57e-0516343MODULE_505
DrugC1 11-32

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

4.58e-34186014CID000443077
DrugC11131

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

4.58e-34186014CID000443076
Drugestriol-16-glucuronide

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

1.73e-32216014CID000122281
Drug7-hydroxycoumarin glucuronide

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

2.31e-32296015CID000125641
Drugestradiol-3-glucuronide

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

1.21e-31236014CID000066651
DrugBP-3,6-quinol

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

3.06e-31336015CID000119292
DrugAC1NOWCJ

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

9.55e-31356015CID005120112
Drug3-[(3S,5R,10S,13R,14S,17R)-3-[(2S,4R,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

9.55e-31356015CID010436171
Drugl-borneol

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

2.74e-30376015CID000010049
DrugAC1NQGK1

UGT1A4 UGT1A1 UGT1A3 GANC UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

5.86e-30526016CID005195977
Drugharmol

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

1.17e-29406015CID000068094
Drugandrosterone glucuronide

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

4.39e-29436015CID000114833
Drug7,8-benzoquinoline

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

4.39e-29436015CID000009191
Drug4-hydroxybiphenyl

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 PORCN UGT1A9 UGT2B28 HAS2 UGT2B11

6.12e-29596016CID000007103
DrugMS-222

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

6.65e-29446015CID000011400
DrugAC1Q6OQG

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

1.19e-28336014CID000009686
Drugsalicylamide

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

3.14e-28486015CID000005147
Drugestrone-3-glucuronide

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

3.37e-28356014CID000115255
Drugcotinine-N-glucuronide

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B7 UGT2B10 UGT1A9

1.25e-27136011CID000000411
Drugtestosterone glucuronide

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

5.05e-27416014CID000108192
Drugpropranolol glucuronide

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

5.82e-27146011CID000119515
Drugphenolphthalein

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

8.38e-27586015CID000004764
Drug4-hydroxyestrone

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

1.12e-26596015CID000018418
Drugacetaminophen glucuronide

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

1.12e-26596015CID000083944
DrugSN-38G

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

1.12e-26596015CID000443154
DrugUDP-alpha-d-xylopyranose

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

1.49e-26606015CID000001165
Drug3-OHBaP

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

3.41e-26636015CID000025890
Drug4-nitrophenyl)imidazole

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B7 UGT1A9

8.04e-26116010CID000123155
DrugMeldola

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

1.23e-25686015CID000081507
Drug3 beta,5 alpha,25R)- 3-hydroxyspirostan-12-one

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

1.97e-25176011CID000003573
Drugeugenol

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

3.98e-25736015CID000003314
DrugN-OH-DABZ

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B7 UGT1A9

4.81e-25126010CID000051366
Drug7-hydroxycoumarin

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

6.22e-25756015CID005281426
DrugAC1N8H7N

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

1.19e-24786015CID004318740
Drugbenzyloxyresorufin

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

1.19e-24786015CID000114982
Drugurochloralic acid

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

1.84e-24596014CID003036914
Drugacridine

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

2.20e-24816015CID000009215
DrugAC1L1OBF

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

2.65e-24206011CID000032736
DrugAC1MRQNQ

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

3.27e-249609CID003522271
DrugDHPASiU

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

3.27e-249609CID000197602
DrugChebi:32663

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

3.27e-249609CID005460873
Drug3-iodophenol

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

3.27e-249609CID000012272
DrugAC1L4J7U

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

3.27e-249609CID000186631
Drug5 alpha-androstane

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

3.98e-24846015CID000094144
Drug7-ethoxycoumarin

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

5.83e-24866015CID000035703
Drugmenthol

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

7.03e-24876015CID000001254
Drugpentoxyresorufin

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

7.03e-24876015CID000107683
DrugNNAL

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9

7.52e-24326012CID000104856
Drugfibrates

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 CPT1A UGT2B11

1.17e-231186016CID000002797
Drug4-aminobiphenyl

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

1.73e-23926015CID000007102
Drugp-nitroanisole

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

1.73e-23926015CID000007485
Drug2-naphthol

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

2.06e-23936015CID000008663
Drugcoumarin-3-carboxylic acid

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B7 UGT1A9

2.18e-23156010CID000010752
DrugDCNB

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

2.90e-23956015CID000007443
Drugethoxyresorufin

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

2.90e-23956015CID000003294
DrugAS-3201

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

3.91e-23246011CID000153948
DrugDB04103

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

4.05e-23976015CID004469987
Drug1-naphthol

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

4.78e-23986015CID000007005
Drug2,2,2-trichloroethanol

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

4.99e-23736014CID000008259
Drug1'-hydroxyestragole

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B7 UGT1A9

5.79e-23166010CID000040003
DrugN-acetylbenzidine

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

6.98e-23256011CID000018787
Drug3-hydroxyandrostan-17-one

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

9.05e-231026015CID000000225
Drug16-epiestriol

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 UGT2B11

1.13e-22776014CID000003269
Drugchrysin

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

1.67e-221066015CID005281607
DrugAC1O5XMV

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.79e-2211609CID006442661
Drug4-nitrophenol

UGT1A4 UGT1A1 UGT1A3 GANC UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 PORCN UGT1A9 UGT2B28 HAS2 UGT2B11

1.83e-221776017CID000000980
Drugfluconazole

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

1.94e-221076015CID000003365
Drugdiflunisal

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

2.03e-22276011CID000003059
Drug2-naphthylamine

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

3.01e-221106015CID000007057
Drugethyl-beta-D-6-glucosiduronic acid

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B7 UGT1A9

3.15e-22186010CID000152226
Drug2,3,7-trichlorodibenzo-p-dioxin

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B7 UGT1A9

3.15e-22186010CID000036614
DrugApApG

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B7 UGT1A9

3.15e-22186010CID003081975
DrugSN-38

UGT1A4 UGT1A1 UGT1A3 ABCA2 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 ST3GAL4 UGT2B28 HAS2 UGT2B11

3.61e-221846017CID000104842
DrugPTBP

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9

3.61e-22426012CID000007393
Drug7-hydroxy-4-trifluoromethylcoumarin

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

5.37e-22296011CID005375667
Drugtrans-3'-hydroxycotinine

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

5.37e-22296011CID000000414
Drugalmokalant

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B7 UGT1A9

6.64e-22196010CID003033962
Druglithocholic acid

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

6.96e-221166015CID000009903
Drugethoxyquin

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

6.96e-221166015CID000003293
Drug1-O-beta-D-glucopyranosyl-D-mannitol

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

7.15e-2212609CID000088735
Drug2,4,6-TCB

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

7.15e-2212609CID000037247
Drug7,7,7-triphenylheptanoic acid

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

7.15e-2212609CID000276709
Drugnonanoyl-N-methylglucamide

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

7.15e-2212609CID000160090
DrugAC1Q7AUJ

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

7.97e-221176015CID000003303
Drugtolcapone

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

8.47e-22306011CID004659569
Drugalpha-naphthoflavone

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

9.11e-221186015CID000011790
Drugbenzphetamine

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

1.04e-211196015CID000002341
Drugtritanol

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

2.32e-2113609CID000006457
Drug5-azido-UDP-glucuronic acid

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

2.32e-2113609CID003081279
Drughexobarbital

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

2.89e-211276015CID000003608
DrugR(-)-Denopamine

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

2.98e-21336011CID000003818
DrugAC1L1FK5

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

3.69e-211296015CID000003272
DrugPCB-61

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

6.48e-2114609CID000036401
Drugoltipraz

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

9.44e-211376015CID000047318
Drug2,2',3,5,5'-pentachlorobiphenyl

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.62e-2015609CID000040469
Drugsulforaphane nitrile

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.62e-2015609CID000543743
Drugafloqualone

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.62e-2015609CID000002040
Drugnaphthyl sulphate

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.62e-2015609CID000114775
Druganiline

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

1.65e-201426015CID000006115
Drugbutylated hydroxytoluene

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B28 HAS2 UGT2B11

1.84e-201436015CID000031404
DiseaseX-11442 measurement

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

2.69e-259599EFO_0021236
DiseaseX-11441 measurement

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

2.69e-259599EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

2.69e-259599EFO_0004739
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

2.69e-259599EFO_0004570, GO_0009410
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

2.69e-2410599EFO_0802185
Diseasebilirubin measurement, response to tenofovir

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

2.69e-2410599EFO_0004570, EFO_0009279
DiseaseX-21796 measurement

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.48e-2311599EFO_0800825
Diseaseinsomnia, bilirubin measurement

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.48e-2311599EFO_0004570, EFO_0004698
Diseasehistidine betaine (hercynine) measurement

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.48e-2311599EFO_0800972
Diseasealdosterone measurement

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.48e-2311599EFO_0010219
Diseasebiliverdin measurement

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

5.90e-2312599EFO_0021033
DiseaseX-11793--oxidized bilirubin measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.56e-228598EFO_0021260
DiseaseSuccinimide measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.56e-228598EFO_0022118
DiseaseX-11530 measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.56e-228598EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.56e-228598EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.56e-228598EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.56e-228598EFO_0800696
DiseaseX-10458 measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.56e-228598EFO_0800692
DiseaseX-24849 measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.56e-228598EFO_0800909
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.56e-228598EFO_0802740
DiseaseX-16946 measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.56e-228598EFO_0800766
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.40e-219598EFO_0801037
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.40e-219598EFO_0802127
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.40e-219598EFO_0801036
DiseaseX-11880 measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.40e-219598EFO_0800698
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.40e-219598EFO_0020691
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

6.47e-2117599EFO_0004611, EFO_0007800
DiseaseX-21448 measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

6.99e-2110598EFO_0800816
DiseaseX-23974 measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

6.99e-2110598EFO_0800867
Diseaseplasma N-desmethylclozapine measurement

UGT1A4 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B10 UGT1A9

2.56e-2011598EFO_0600039
Diseasep-cresol glucuronide measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

7.66e-2012598EFO_0800079
Diseaseretinol dehydrogenase 16 measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.99e-1913598EFO_0802007
Diseasepregnenetriol disulfate measurement

UGT1A4 ZNF680 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.99e-1913598EFO_0800587
Diseaseserum N-desmethylclozapine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B10 UGT1A9

7.06e-198597EFO_0600043
Diseasexanthurenate measurement

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

2.62e-1829599EFO_0010551
Diseaseresponse to dolutegravir

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

3.73e-1830599EFO_0600017
Diseaseangiopoietin-related protein 1 measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

6.71e-1818598EFO_0801382
Diseasepregnenetriol sulfate measurement

UGT1A4 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

2.90e-1711597EFO_0800586
Diseasetissue factor measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

3.11e-1721598EFO_0010623
Diseasevitamin D deficiency

UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9 UGT2B11

3.21e-1737599EFO_0003762
Diseaseplasma clozapine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.37e-158596EFO_0600038
DiseaseX-21441 measurement

UGT1A4 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.69e-1517597EFO_0800814
Diseaseurate measurement, spine bone mineral density

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

2.66e-1558599EFO_0004531, EFO_0007701
DiseaseN-acetyl-4-chlorophenylalanine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A9

2.69e-145595EFO_0801060
Diseasenuclear receptor subfamily 1 group D member 2 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A9

2.69e-145595EFO_0801853
Diseasevitamin D measurement, COVID-19

UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT1A9

6.59e-1449598EFO_0004631, MONDO_0100096
Diseasecholelithiasis

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

1.36e-1388599EFO_0004799
DiseaseX-21339 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A9

5.62e-137595EFO_0800808
Diseasegallstones

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

9.05e-13108599EFO_0004210
Diseasevitamin D measurement

UGT1A4 ZNF680 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B11

2.71e-123365912EFO_0004631
Diseasethyroxine measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

5.47e-1283598EFO_0005130
Diseasehormone measurement

UGT1A4 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

6.04e-1284598EFO_0004730
Diseasemetabolite measurement

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 UGT2B11

6.58e-115605913EFO_0004725
Disease5-hydroxyindole sulfate measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.20e-115594EFO_0800085
Diseaseplasma clozapine-to-N-desmethylclozapine ratio measurement

UGT2B4 UGT2B7 UGT2B10 UGT2B11

1.80e-099594EFO_0600040
Diseaseneuroblastoma, cutaneous melanoma

UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A9

2.55e-0928595EFO_0000389, EFO_0000621
Diseaseblood 4-oxo-retinoic acid measurement

UGT1A10 UGT1A8 UGT1A9

7.59e-093593EFO_0022216
Diseaseindole-3-carboxylate measurement

UGT1A10 UGT1A8 UGT1A9

7.59e-093593EFO_0800043
Diseasebilirubin measurement

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B10 UGT1A9

1.68e-084425910EFO_0004570
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

UGT1A1 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A9 CPT1A

1.81e-08147597DOID:9352 (biomarker_via_orthology)
Diseaseapolipoprotein B measurement

UGT1A4 UGT1A3 ACACB UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9 ST3GAL4 ADTRP

7.14e-086635911EFO_0004615
Diseasenon-high density lipoprotein cholesterol measurement

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9 ST3GAL4 ADTRP

1.48e-077135911EFO_0005689
Disease3-carboxy-4-methyl-5-pentyl-2-furanpropionate (3-CMPFP) measurement

UGT1A10 UGT1A8 UGT1A9

1.51e-076593EFO_0800566
Diseaseindoleacetate measurement

UGT1A10 UGT1A8 UGT1A9

9.02e-0710593EFO_0021015
Diseaseserum gamma-glutamyl transferase measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT2B4 UGT2B7 UGT2B10 UGT1A9 SLC28A3 ST3GAL4 SIPA1L2

1.71e-069145911EFO_0004532
DiseaseX-24588 measurement

UGT1A10 UGT1A8 UGT1A9

2.14e-0613593EFO_0800898
DiseaseX-19141 measurement

UGT2B4 UGT2B7 UGT2B11

2.14e-0613593EFO_0800799
Diseaseserum metabolite measurement

UGT1A4 UGT1A1 UGT1A3 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9 SLC28A3 CPT1A

2.35e-069455911EFO_0005653
Diseasephosphatidylcholine 36:4 measurement

UGT2B4 UGT2B28 UGT2B11

6.07e-0618593EFO_0010382
Diseasetestosterone measurement

UGT1A4 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT2B4 UGT2B7 UGT2B10 UGT1A9 SLC28A3 UGT2B11

6.85e-0612755912EFO_0004908
Diseasefree androgen index

UGT1A4 UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A5 UGT1A9

9.62e-06374597EFO_0007005
DiseaseX-24947 measurement

UGT2B4 UGT2B7 UGT2B11

1.14e-0522593EFO_0800910
Diseasecerebellar ataxia, mental retardation and dysequlibrium syndrome (is_implicated_in)

ATP8A2 CA8

2.35e-054592DOID:0050997 (is_implicated_in)
DiseaseDysequilibrium syndrome

ATP8A2 CA8

3.92e-055592C0394006
Diseaselipid metabolism disorder (is_implicated_in)

NPY5R CPT1A

5.87e-056592DOID:3146 (is_implicated_in)
Diseasevanillylmandelate (VMA) measurement

UGT2B4 UGT2B10

8.20e-057592EFO_0800119
Diseasedeoxycholic acid glucuronide measurement

UGT2B7 UGT2B10

1.09e-048592EFO_0800575
Diseaseurate measurement, bone density

UGT1A10 UGT1A8 UGT1A7 UGT1A6 UGT1A9 ALG8 DNAH9

2.29e-04619597EFO_0003923, EFO_0004531
Diseasedisease progression measurement

UGT2B4 UGT2B7 UGT2B11

2.52e-0461593EFO_0008336
Diseasecerebellar ataxia, mental retardation and dysequlibrium syndrome (implicated_via_orthology)

ATP8A2 CA8

2.56e-0412592DOID:0050997 (implicated_via_orthology)
Diseasedodecanedioate measurement

UGT1A10 UGT1A8

2.56e-0412592EFO_0021054
DiseaseLung cancer

PIK3CA MAP3K8

3.52e-0414592cv:C0242379
DiseaseLUNG CANCER

PIK3CA MAP3K8

3.52e-0414592211980
DiseaseNeoplasm of lung

PIK3CA MAP3K8

3.52e-0414592cv:C0024121
DiseasePigmented Basal Cell Carcinoma

PIK3CA PTCH2

1.44e-0328592C1368275
Diseaseurinary metabolite measurement

UGT2B4 UGT2B7 UGT2B11 CA8

1.48e-03245594EFO_0005116
DiseaseCarcinoma, Basal Cell

PIK3CA PTCH2

1.54e-0329592C4721806

Protein segments in the cluster

PeptideGeneStartEntry
FWVEFVMRHKGAPHL

UGT1A3

461

P35503
LWLKFHRHQTEMIIT

EOMES

276

O95936
LHNTFLELWTMVHFL

EP400

1251

Q96L91
HHTWLIFVFLVEMGK

AGBL3

731

Q8NEM8
VIPVWLNHAMHTFIF

ADTRP

121

Q96IZ2
SHLVIHNLFEGMIWF

CDS2

211

O95674
AIHWAAYMGHIEVVK

ANKRD28

176

O15084
LKVLLSYHGWMFTEH

CPT1A

126

P50416
MGVHPVIHFLAWFLE

ABCA13

3606

Q86UQ4
RMEAHAKFAVLWHLT

DOP1A

926

Q5JWR5
VVLLSVFCWHMHKKG

FLRT2

556

O43155
HSLILFWFPMKALEH

ATP8A2

971

Q9NTI2
GMAEEIKHMFHVAWV

ACACB

1836

O00763
DMQKLTHGVLHTKFW

PLD3

191

Q8IV08
IFVHGDLKWDIFQVM

KIAA1109

4546

Q2LD37
WTIFHAMRHPIIFFS

GPR50

306

Q13585
IWVTKHVLKGLDFLH

MAP3K8

231

P41279
HVHWMSESGIIDVFL

GANC

321

Q8TET4
IWVIGFFHALLHSVM

OR12D2

146

P58182
QRIGHFFFWHLKSEM

PIK3CA

661

P42336
QPKMLAIFWFHAHEI

OR52R1

81

Q8NGF1
HFFQLHMVWVVLLSL

PORCN

66

Q9H237
LEEVHIHSTMIGKIW

GJA9

11

P57773
VNFKAFPMELHLIHW

CA8

131

P35219
KHHLWMTYEAIITGF

HAS2

371

Q92819
VLMHSHVVIIWLFLA

ABCA2

776

Q9BZC7
ASHKAVLHGKFMWVI

ATRNL1

306

Q5VV63
VEIWLNHVLGHMKAT

DNAH9

1676

Q9NYC9
VMWEIFEDGHLSHFI

PRDM14

301

Q9GZV8
VFAVSWMPLHLFHVV

NPY5R

376

Q15761
FSHKFMHWQEELLLG

PTCH2

286

Q9Y6C5
EGVRDMLVKHHLFSW

SGSM3

731

Q96HU1
DAHLFSIGAIMWHVI

SIPA1L2

846

Q9P2F8
LLVLVAFKAMDFHWI

ST3GAL4

186

Q11206
FVVWDHLMAKYEHRI

SLC28A3

141

Q9HAS3
ICMVFEVLGHHLLKW

SRPK1

161

Q96SB4
VHFHVMRLTDSLFLW

PSMG4

26

Q5JS54
LSSFMFGWHVHEKAI

ALG8

371

Q9BVK2
KVFRWFHEHSAMLLA

RNF213

2646

Q63HN8
FGFIENLMWHKLVHQ

ZNF865

706

P0CJ78
DHDVWKLNVAHVLFM

TTC30B

456

Q8N4P2
VFWVEFVMRHKGAPH

UGT1A10

456

Q9HAW8
DWLHHLLMGTRILFK

SNX14

806

Q9Y5W7
HFWIVFVMPRAKGHI

TMPRSS7

176

Q7RTY8
VFWIEFVMRHKGAKH

UGT2B4

461

P06133
DLAVFWVEFVMRHKG

UGT1A1

456

P22309
FWVEFVMRHKGAPHL

UGT1A5

461

P35504
WFLTMFTHVFPLHKI

TBCK

626

Q8TEA7
VFWVEFVMRHKGAPH

UGT1A9

456

O60656
VFWIEFVMPHKGAKH

UGT2B11

461

O75310
DHDVWKLNVAHVLFM

TTC30A

456

Q86WT1
FWIEFVMRHKGAKHL

UGT2B10

461

P36537
RFHWIHTPLVLTGKM

TMEM130

71

Q8N3G9
IFTHIFILEMVLKWV

SCN11A

1096

Q9UI33
YWVLSFTKHMIIHRG

ZNF355P

166

Q9NSJ1
LAVFWVEFVMRHKGA

UGT1A6

456

P19224
VFWIEFVMCHKGAKH

UGT2B28

461

Q9BY64
VFWIEFVMRHKGAKH

UGT2B7

461

P16662
WFSELIKHKGIHMGE

ZNF680

221

Q8NEM1
VFWVEFVMRHKGAPH

UGT1A7

456

Q9HAW7
TAHWHKGTTLMIKFE

TRAPPC5

161

Q8IUR0
VFWVEFVMRHKGAPH

UGT1A8

456

Q9HAW9
FWVEFVMRHKGAPHL

UGT1A4

461

P22310
SFVKLEHWLETLRMH

LIMK1

596

P53667