Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity

FUT3 FUT5

1.43e-052762GO:0017060
GeneOntologyMolecularFunctiontransporter activity

CLCA4 ZACN PSEN1 SLC22A8 SLC22A16 SLC17A9 TMEM94 GLRB NPC1L1 LRRC26 SLC17A4 SCNN1G PEX6 MFSD2B SLC33A1 SLC12A5

2.25e-0512897616GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

CLCA4 ZACN PSEN1 SLC22A8 SLC22A16 SLC17A9 TMEM94 GLRB LRRC26 SLC17A4 SCNN1G MFSD2B SLC33A1 SLC12A5

1.28e-0411807614GO:0022857
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F2 CYP4F12

1.42e-045762GO:0052871
GeneOntologyMolecularFunction4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity

FUT3 FUT5

2.12e-046762GO:0017083
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F2 CYP4F12

2.97e-047762GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F2 CYP4F12

2.97e-047762GO:0018685
GeneOntologyMolecularFunctionalpha-(1->3)-fucosyltransferase activity

FUT3 FUT5

3.94e-048762GO:0046920
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

CLCA4 SLC22A8 GLRB SLC17A4 SLC12A5

4.91e-04171765GO:0015103
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F2 CYP4F12

6.31e-0410762GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F2 CYP4F12

6.31e-0410762GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F2 CYP4F12

6.31e-0410762GO:0102033
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F12

1.09e-0313762GO:0016713
GeneOntologyMolecularFunctionfucosyltransferase activity

FUT3 FUT5

1.26e-0314762GO:0008417
GeneOntologyMolecularFunctionquaternary ammonium group transmembrane transporter activity

SLC22A8 SLC22A16

1.45e-0315762GO:0015651
GeneOntologyMolecularFunctionarachidonate binding

CYP4F2 CYP4F12

1.45e-0315762GO:0050544
GeneOntologyMolecularFunctionicosanoid binding

CYP4F2 CYP4F12

1.66e-0316762GO:0050542
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4F2 CYP4F12

1.66e-0316762GO:0050543
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CLCA4 PSEN1 SLC22A8 TMEM94 GLRB LRRC26 SLC17A4 SCNN1G SLC12A5

2.29e-03758769GO:0015318
GeneOntologyMolecularFunctionfatty acid binding

CYP4F2 CYP4F12 FFAR4

2.32e-0369763GO:0005504
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CLCA4 ZACN PSEN1 TMEM94 GLRB LRRC26 SLC17A4 SCNN1G SLC12A5

3.10e-03793769GO:0015075
GeneOntologyMolecularFunctionpurine ribonucleotide transmembrane transporter activity

SLC17A9 SLC33A1

3.43e-0323762GO:0005346
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4F2 CYP4F12

3.74e-0324762GO:0008392
GeneOntologyMolecularFunctionchannel activity

CLCA4 ZACN PSEN1 GLRB LRRC26 SCNN1G SLC12A5

3.82e-03525767GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CLCA4 ZACN PSEN1 GLRB LRRC26 SCNN1G SLC12A5

3.86e-03526767GO:0022803
GeneOntologyMolecularFunctionadenine nucleotide transmembrane transporter activity

SLC17A9 SLC33A1

4.38e-0326762GO:0000295
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP4F2 CYP4F12

4.72e-0327762GO:0008391
GeneOntologyBiologicalProcessvitamin E metabolic process

NPC1L1 CYP4F2 CYP4F12

8.80e-076743GO:0042360
GeneOntologyBiologicalProcessmenaquinone catabolic process

CYP4F2 CYP4F12

3.80e-053742GO:0042361
GeneOntologyBiologicalProcessmenaquinone metabolic process

CYP4F2 CYP4F12

7.58e-054742GO:0009233
GeneOntologyBiologicalProcessphylloquinone metabolic process

CYP4F2 CYP4F12

7.58e-054742GO:0042374
GeneOntologyBiologicalProcessphylloquinone catabolic process

CYP4F2 CYP4F12

7.58e-054742GO:0042376
GeneOntologyBiologicalProcessvitamin K catabolic process

CYP4F2 CYP4F12

7.58e-054742GO:0042377
GeneOntologyBiologicalProcessoligosaccharide biosynthetic process

ABO FUT3 FUT5

1.85e-0431743GO:0009312
GeneOntologyBiologicalProcessleukotriene B4 catabolic process

CYP4F2 CYP4F12

1.89e-046742GO:0036101
GeneOntologyBiologicalProcessprostaglandin catabolic process

CYP4F2 CYP4F12

1.89e-046742GO:1905344
GeneOntologyBiologicalProcessprostanoid catabolic process

CYP4F2 CYP4F12

1.89e-046742GO:0062232
GeneOntologyBiologicalProcessleukotriene B4 metabolic process

CYP4F2 CYP4F12

2.64e-047742GO:0036102
GeneOntologyCellularComponentapical part of cell

CLCA4 BMPR2 MAL SLC22A8 LMO7 DSTYK NPC1L1 SLC17A4 SCNN1G ITGA8 CYP4F2 CYP4F12

1.22e-065927512GO:0045177
GeneOntologyCellularComponentapical plasma membrane

CLCA4 BMPR2 MAL SLC22A8 LMO7 DSTYK NPC1L1 SLC17A4 SCNN1G CYP4F2 CYP4F12

1.25e-064877511GO:0016324
GeneOntologyCellularComponentNURF complex

RBBP4 RBBP7

2.64e-047752GO:0016589
GeneOntologyCellularComponentendoplasmic reticulum membrane

LMF2 PSEN1 ANKRD13C TMEM94 FA2H CANX UGT2A1 CYP4F2 CYP4F12 SELENOI TRDN SLC33A1 AWAT2

6.37e-0412937513GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

LMF2 PSEN1 ANKRD13C TMEM94 FA2H CANX UGT2A1 CYP4F2 CYP4F12 SELENOI TRDN SLC33A1 AWAT2

6.65e-0412997513GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

LMF2 PSEN1 ANKRD13C TMEM94 FA2H CANX UGT2A1 CYP4F2 CYP4F12 SELENOI TRDN SLC33A1 AWAT2

8.11e-0413277513GO:0042175
GeneOntologyCellularComponentISWI-type complex

RBBP4 RBBP7

1.12e-0314752GO:0031010
GeneOntologyCellularComponentCHD-type complex

RBBP4 RBBP7

1.67e-0317752GO:0090545
GeneOntologyCellularComponentESC/E(Z) complex

RBBP4 RBBP7

1.67e-0317752GO:0035098
GeneOntologyCellularComponentNuRD complex

RBBP4 RBBP7

1.67e-0317752GO:0016581
DomainMFS_dom

SLC22A8 SLC22A16 SLC17A9 SLC17A4 MFSD2B SLC33A1

1.51e-05134746IPR020846
DomainCAF1C_H4-bd

RBBP4 RBBP7

4.63e-053742PF12265
DomainHistone-bd_RBBP4_N

RBBP4 RBBP7

4.63e-053742IPR022052
DomainMFS

SLC22A8 SLC22A16 SLC17A9 SLC17A4 MFSD2B

6.91e-05108745PS50850
DomainGlyco_transf_10

FUT3 FUT5

4.27e-048742PF00852
DomainGlyco_tran_10_N

FUT3 FUT5

4.27e-048742PF17039
DomainGlyco_trans_10

FUT3 FUT5

4.27e-048742IPR001503
DomainGlyco_tran_10_N

FUT3 FUT5

4.27e-048742IPR031481
DomainMFS_1

SLC22A8 SLC17A9 SLC17A4

3.54e-0377743PF07690
DomainMFS

SLC22A8 SLC17A9 SLC17A4

3.54e-0377743IPR011701
PathwayKEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES

ABO FUT3 FUT5

1.23e-0426533M17377
PathwayKEGG_MEDICUS_REFERENCE_LEWIS_X_ANTIGEN_BIOSYNTHESIS

FUT3 FUT5

1.38e-045532M47966
PathwayKEGG_MEDICUS_REFERENCE_SIALYL_LEWIS_X_ANTIGEN_BIOSYNTHESIS

FUT3 FUT5

2.06e-046532M47967
Pubmed

Expression of CYP4F2 in human liver and kidney: assessment using targeted peptide antibodies.

CYP4F2 CYP4F12

4.97e-06278218662666
Pubmed

Down-regulation of FUT3 and FUT5 by shRNA alters Lewis antigens expression and reduces the adhesion capacities of gastric cancer cells.

FUT3 FUT5

4.97e-06278221978830
Pubmed

Characterization of the gene encoding mouse retinoblastoma binding protein-7, a component of chromatin-remodeling complexes.

RBBP4 RBBP7

4.97e-06278212376095
Pubmed

Interpreting the molecular mechanisms of RBBP4/7 and their roles in human diseases (Review).

RBBP4 RBBP7

4.97e-06278238577935
Pubmed

Acceptor specificity of different length constructs of human recombinant alpha 1,3/4-fucosyltransferases. Replacement of the stem region and the transmembrane domain of fucosyltransferase V by protein A results in an enzyme with GDP-fucose hydrolyzing activity.

FUT3 FUT5

4.97e-0627827721776
Pubmed

Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development.

RBBP4 RBBP7

4.97e-06278234709113
Pubmed

The role of retinoblastoma-associated proteins 46 and 48 in estrogen receptor alpha mediated gene expression.

RBBP4 RBBP7

1.49e-05378218577416
Pubmed

Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms.

FUT3 FUT5

1.49e-0537827650030
Pubmed

Overexpressed N-fucosylation on the cell surface driven by FUT3, 5, and 6 promotes cell motilities in metastatic pancreatic cancer cell lines.

FUT3 FUT5

1.49e-05378230808544
Pubmed

Histo-blood group gene polymorphisms as potential genetic modifiers of infection and cystic fibrosis lung disease severity.

ABO FUT3

1.49e-05378219169360
Pubmed

Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast.

RBBP4 RBBP7

1.49e-0537827503932
Pubmed

ABO/secretor genetic complex is associated with the susceptibility of childhood asthma in Taiwan.

ABO FUT3

1.49e-05378216008680
Pubmed

Polymorphisms of Lewis and Secretor genes are related to breast cancer and metastasis in axillary lymph nodes.

ABO FUT3

1.49e-05378220514537
Pubmed

ABO blood type, Lewis and Secretor genotypes, and chronic atrophic gastritis: a cross-sectional study in Japan.

ABO FUT3

1.49e-05378212673421
Pubmed

Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities.

FUT3 FUT5

1.49e-0537821740457
Pubmed

The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/7.

RBBP4 RBBP7

1.49e-05378227144666
Pubmed

Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.

CYP4F2 CYP4F12

2.97e-05478222665481
Pubmed

Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

CYP4F2 CYP4F12

2.97e-05478211185557
Pubmed

Activation of host antiviral RNA-sensing factors necessary for herpes simplex virus type 1-activated transcription of host cell fucosyltransferase genes FUT3, FUT5, and FUT6 and subsequent expression of sLe(x) in virus-infected cells.

FUT3 FUT5

2.97e-05478219349624
Pubmed

Histone binding protein RbAp48 interacts with a complex of CREB binding protein and phosphorylated CREB.

RBBP4 RBBP7

2.97e-05478210866654
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F2 CYP4F12

2.97e-05478218065749
Pubmed

Isolation of human NURF: a regulator of Engrailed gene expression.

RBBP4 RBBP7

2.97e-05478214609955
Pubmed

Identification of a genetic interaction between the tumor suppressor EAF2 and the retinoblastoma protein (Rb) signaling pathway in C. elegans and prostate cancer cells.

RBBP4 RBBP7

2.97e-05478224727455
Pubmed

The G protein-coupled receptor repertoires of human and mouse.

GPR152 GPR101 GPR151 FFAR4

3.10e-057978412679517
Pubmed

Mrg15 stimulates Ash1 H3K36 methyltransferase activity and facilitates Ash1 Trithorax group protein function in Drosophila.

RBBP4 RBBP7

4.94e-05578229158494
Pubmed

Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.

CYP4F2 CYP4F12

4.94e-05578222969154
Pubmed

Differential effects of extracellular ATP on chloride transport in cortical collecting duct cells.

CLCA4 SCNN1G

4.94e-05578222647633
Pubmed

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex.

RBBP4 RBBP7

4.94e-05578210471499
Pubmed

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.

CYP4F2 CYP4F12

4.94e-05578221466787
Pubmed

Distinct human α(1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells.

FUT3 FUT5

4.94e-05578229593094
Pubmed

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.

IARS2 PIK3C2B LMO7 GIGYF2 DYNC1H1

7.05e-0519078515161933
Pubmed

SUMO modification enhances p66-mediated transcriptional repression of the Mi-2/NuRD complex.

RBBP4 RBBP7

7.40e-05678216738318
Pubmed

Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase.

RBBP4 RBBP7

7.40e-0567829427644
Pubmed

CRL4(RBBP7) is required for efficient CENP-A deposition at centromeres.

RBBP4 RBBP7

7.40e-05678225795299
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F2 CYP4F12

7.40e-0567829068972
Pubmed

Functional and physical interaction between the histone methyl transferase Suv39H1 and histone deacetylases.

RBBP4 RBBP7

7.40e-05678211788710
Pubmed

The structure of the core NuRD repression complex provides insights into its interaction with chromatin.

RBBP4 RBBP7

7.40e-05678227098840
Pubmed

Expression, purification and characterization of the human MTA2-RBBP7 complex.

RBBP4 RBBP7

7.40e-05678228179136
Pubmed

BRCA1 interacts with components of the histone deacetylase complex.

RBBP4 RBBP7

7.40e-05678210220405
Pubmed

Functional characterization of the interactions between endosomal adaptor protein APPL1 and the NuRD co-repressor complex.

RBBP4 RBBP7

1.04e-04778219686092
Pubmed

Smad-dependent recruitment of a histone deacetylase/Sin3A complex modulates the bone morphogenetic protein-dependent transcriptional repressor activity of Nkx3.2.

RBBP4 RBBP7

1.04e-04778214612411
Pubmed

CDK2AP1/DOC-1 is a bona fide subunit of the Mi-2/NuRD complex.

RBBP4 RBBP7

1.04e-04778220523938
Pubmed

Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice.

CYP4F2 CYP4F12

1.04e-04778222160543
Pubmed

Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein.

RBBP4 RBBP7

1.04e-04778212435631
Pubmed

Atypical Mowat-Wilson patient confirms the importance of the novel association between ZFHX1B/SIP1 and NuRD corepressor complex.

RBBP4 RBBP7

1.38e-04878218182442
Pubmed

Differential association of products of alternative transcripts of the candidate tumor suppressor ING1 with the mSin3/HDAC1 transcriptional corepressor complex.

RBBP4 RBBP7

1.38e-04878211118440
Pubmed

Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation.

RBBP4 RBBP7

1.38e-04878210471500
Pubmed

The zinc finger and C-terminal domains of MTA proteins are required for FOG-2-mediated transcriptional repression via the NuRD complex.

RBBP4 RBBP7

1.38e-04878218067919
Pubmed

Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation.

RBBP4 RBBP7

1.38e-04878220144788
Pubmed

The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes.

RBBP4 RBBP7

1.38e-04878211297506
Pubmed

MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer.

RBBP4 RBBP7

1.38e-04878212705869
Pubmed

Identification of G protein-coupled receptor genes from the human genome sequence.

GPR152 GPR101 GPR151

1.54e-044678312044878
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

CLCA4 MAL TMEM94 FA2H CANX GDPD2 TMEM19 SLC12A5

1.71e-0469778828298427
Pubmed

Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity.

RBBP4 RBBP7

1.77e-04978223104054
Pubmed

Identification of a nuclear domain with deacetylase activity.

RBBP4 RBBP7

1.77e-04978210984530
Pubmed

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells.

RBBP4 RBBP7

1.77e-04978220075857
Pubmed

Identification and functional characterization of the p66/p68 components of the MeCP1 complex.

RBBP4 RBBP7

1.77e-04978211756549
Pubmed

RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest.

RBBP4 RBBP7

1.77e-04978211283269
Pubmed

Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex.

RBBP4 RBBP7

1.77e-0497829150135
Pubmed

RBB, a novel transcription repressor, represses the transcription of HDM2 oncogene.

RBBP4 RBBP7

1.77e-04978222926524
Pubmed

ZIP: a novel transcription repressor, represses EGFR oncogene and suppresses breast carcinogenesis.

RBBP4 RBBP7

2.21e-041078219644445
Pubmed

Protein kinase CK2-mediated phosphorylation of HDAC2 regulates co-repressor formation, deacetylase activity and acetylation of HDAC2 by cigarette smoke and aldehydes.

RBBP4 RBBP7

2.21e-041078220388487
Pubmed

PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex.

RBBP4 RBBP7

2.21e-041078234180153
Pubmed

Identification of a novel BRMS1-homologue protein p40 as a component of the mSin3A/p33(ING1b)/HDAC1 deacetylase complex.

RBBP4 RBBP7

2.21e-041078215451426
Pubmed

Increased interaction between DJ-1 and the Mi-2/ nucleosome remodelling and deacetylase complex during cellular stress.

RBBP4 RBBP7

2.21e-041078220127688
Pubmed

BCL11B functionally associates with the NuRD complex in T lymphocytes to repress targeted promoter.

RBBP4 RBBP7

2.21e-041078216091750
Pubmed

EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells.

RBBP4 RBBP7

2.21e-041078231451685
Pubmed

MBD3L1 is a transcriptional repressor that interacts with methyl-CpG-binding protein 2 (MBD2) and components of the NuRD complex.

RBBP4 RBBP7

2.70e-041178215456747
Pubmed

Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal.

RBBP4 RBBP7

2.70e-041178222438827
Pubmed

The program for processing newly synthesized histones H3.1 and H4.

RBBP4 RBBP7

2.70e-041178220953179
Pubmed

Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes.

RBBP4 RBBP7

2.70e-041178229263092
Pubmed

An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting.

RBBP4 RBBP7

2.70e-041178223273982
Pubmed

Breast cancer metastasis suppressor 1 (BRMS1) forms complexes with retinoblastoma-binding protein 1 (RBP1) and the mSin3 histone deacetylase complex and represses transcription.

RBBP4 RBBP7

2.70e-041178214581478
Pubmed

USP11 acts as a histone deubiquitinase functioning in chromatin reorganization during DNA repair.

RBBP4 RBBP7

3.23e-041278231504778
Pubmed

The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes.

RBBP4 RBBP7

3.23e-041278223708667
Pubmed

NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities.

RBBP4 RBBP7

3.23e-04127829885572
Pubmed

NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment.

RBBP4 RBBP7

3.23e-041278222560079
Pubmed

Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14.

RBBP4 RBBP7

3.23e-041278221937684
Pubmed

The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.

LMO7 RBBP4 RBBP7 GIGYF2

3.43e-0414778428977470
Pubmed

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).

FAT2 TNFSF13 LRRC26 MUC16 FUT3 DYNC1H1

3.56e-0441778619199708
Pubmed

The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2.

RBBP4 RBBP7

3.81e-041378212124384
Pubmed

LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer.

RBBP4 RBBP7

3.81e-041378219703393
Pubmed

Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells.

PSEN1 CANX

3.81e-041378222375059
Pubmed

Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China.

ABO FUT3

3.81e-041378224941225
Pubmed

The metastasis-associated proteins 1 and 2 form distinct protein complexes with histone deacetylase activity.

RBBP4 RBBP7

3.81e-041378212920132
Pubmed

Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex.

RBBP4 RBBP7 DYNC1H1

4.10e-046478322865885
Pubmed

GATA-1 forms distinct activating and repressive complexes in erythroid cells.

RBBP4 RBBP7

4.44e-041478215920471
Pubmed

MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.

RBBP4 RBBP7

4.44e-041478216428440
Pubmed

Identification of novel target genes specifically activated by deregulated E2F in human normal fibroblasts.

RBBP4 RBBP7

4.44e-041478226201719
Pubmed

NuRD-ZNF827 recruitment to telomeres creates a molecular scaffold for homologous recombination.

RBBP4 RBBP7

4.44e-041478225150861
Pubmed

Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM.

EME2 FANCA

5.12e-041578217289582
Pubmed

Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis.

RBBP4 RBBP7

5.12e-041578230135474
Pubmed

DLX1 and the NuRD complex cooperate in enhancer decommissioning and transcriptional repression.

RBBP4 RBBP7

5.12e-041578235695185
Pubmed

Codanin-1, mutated in the anaemic disease CDAI, regulates Asf1 function in S-phase histone supply.

RBBP4 RBBP7

5.12e-041578222407294
Pubmed

Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism.

FUT3 FUT5

5.12e-041578211698403
Pubmed

The chromatin remodeling factor CHD5 is a transcriptional repressor of WEE1.

RBBP4 RBBP7

5.12e-041578225247294
Pubmed

Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex.

RBBP4 RBBP7

5.12e-04157829804427
Pubmed

NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development.

RBBP4 RBBP7

5.12e-041578219927129
Pubmed

MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing.

RBBP4 RBBP7

5.12e-041578215701600
Pubmed

Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1).

RBBP4 RBBP7

5.84e-041678211784859
InteractionFUT9 interactions

CANX HSF2BP TSSK3

1.48e-0514713int:FUT9
InteractionFCER1G interactions

CLCA4 TMEM31 FA2H CYP4F2 TMEM19

1.82e-0592715int:FCER1G
InteractionPEX3 interactions

IARS2 LMF2 ANKRD13C CANX PEX6 DYNC1H1

3.10e-05171716int:PEX3
InteractionSLC10A1 interactions

MAL FA2H GPR152 TMEM222 GPR151

6.81e-05121715int:SLC10A1
InteractionCREB3L1 interactions

MAL FA2H CYP4F2 TMEM222 TMEM19 GPR151

8.74e-05206716int:CREB3L1
InteractionELOVL4 interactions

CLCA4 FA2H CYP4F2 TMEM222 TMEM19

8.90e-05128715int:ELOVL4
InteractionMC4R interactions

MAL TMEM94 TMEM19

9.12e-0525713int:MC4R
InteractionCYB561A3 interactions

TMEM31 GPR152 GPR101

9.12e-0525713int:CYB561A3
GeneFamilyLysine methyltransferases|Myb/SANT domain containing|Polycomb repressive complex 2

RBBP4 RBBP7

1.26e-0465321347
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

RBBP4 RBBP7

3.00e-0495321306
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

RBBP4 RBBP7

5.46e-04125321243
GeneFamilyPHD finger proteins|NuRD complex

RBBP4 RBBP7

5.46e-04125321305
GeneFamilyFucosyltransferases|Blood group antigens

FUT3 FUT5

6.44e-0413532434
GeneFamilySolute carriers

SLC22A8 SLC22A16 SLC17A9 SLC17A4 SLC33A1 SLC12A5

1.01e-03395536752
GeneFamilyG protein-coupled receptors, Class A orphans

GPR152 GPR101 GPR151

1.55e-0378533262
GeneFamilyCytochrome P450 family 4

CYP4F2 CYP4F12

4.98e-03365321003
GeneFamilyGlycosyltransferase family 6|Blood group antigens

ABO FUT3

5.26e-0337532454
ToppCelldistal-Epithelial-Goblet|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FA2H UGT2A1 LRRC26 SCNN1G MUC16 CYP4F12 FUT3

5.63e-08197787da1ed7303cc9cb2d205c0e5c49c52544d3540951
ToppCelldistal-Epithelial-Goblet-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FA2H UGT2A1 LRRC26 SCNN1G MUC16 CYP4F12 FUT3

5.63e-081977873fbf456ae4f73da4f6254a6f0d24f0ec27d7a3cc
ToppCellBiopsy_Control_(H.)-Epithelial-MUC5AC+_High|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

CLCA4 FAT2 UGT2A1 LRRC26 SCNN1G MUC16 CYP4F12

6.03e-08199787a5240868cea40574ed4ee45eb27a00c1812957ed
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LMO7 UGT2A1 SCNN1G MUC16 CYP4F12 FUT3

1.25e-06196786a4d05d85fbafa869df19bba3881020ea433d81fb
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LMO7 UGT2A1 SCNN1G MUC16 CYP4F12 FUT3

1.25e-0619678691a3c3091064f1f5a3bdc1dd5883fc24dce8ff05
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LMO7 UGT2A1 SCNN1G MUC16 CYP4F12 FUT3

1.25e-06196786e819088a74d29e958371aa851ac9c74ec55367b7
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

LMO7 UGT2A1 SCNN1G MUC16 CYP4F12 FUT3

1.25e-06196786e675d661b6494ac3a85ba7ee5bdeaa98b8bbe957
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|Epithelial / Condition, Lineage and Cell class

CLCA4 FAT2 NYNRIN UGT2A1 SCNN1G MUC16

1.29e-0619778678ed2810e5a765327e7a6da0ca5d4854bf7a0b6f
ToppCelldistal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FA2H UGT2A1 LRRC26 SCNN1G MUC16 FUT3

1.29e-06197786a00784ccfb1de6a96b91e2a8a2889b69f31a33da
ToppCellMild_COVID-19-Epithelial-Basal/Club|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

LMO7 UGT2A1 SCNN1G MUC16 CYP4F12 FUT3

1.29e-061977864cc5b778e1e2c6c149160fa147c172977c0fa8eb
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LMO7 UGT2A1 LRRC26 SCNN1G MUC16 FUT3

1.37e-0619978670c0b9cff195d3d24e98443a729e211cac20c90f
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CLCA4 UGT2A1 SCNN1G MUC16 CYP4F12 FUT3

1.37e-061997863c3133d0aa65338a576634def13e7f0f5c573a10
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CLCA4 FAT2 FA2H UGT2A1 SCNN1G MUC16

1.37e-06199786f5c3561744e2a0e7716657cb521acb1d8f054b41
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CLCA4 UGT2A1 LRRC26 SCNN1G MUC16 FUT3

1.37e-06199786a706ad5cd5e0dc8d7e925a05e45b07d35963f294
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal-Suprabasal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CLCA4 FAT2 UGT2A1 MUC16 CYP4F12 FUT3

1.41e-06200786ce969c958a31145bbfe315a9a865d7900ecc9549
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LMO7 UGT2A1 SCNN1G MUC16 NPW

1.26e-0517178525c1979e972c959e1ce4c57804f976f53a247ad7
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LMO7 UGT2A1 SCNN1G MUC16 NPW

1.26e-05171785fe27bf581c75ef33c2848878e51ed16b275a4c8e
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue|TCGA-Colorectal / Sample_Type by Project: Shred V9

CLCA4 MAL SLC17A4 GDPD2 TNXB

1.30e-0517278594842346c84542a5243bd765e49f4af8bc5182db
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue|TCGA-Colorectal / Sample_Type by Project: Shred V9

CLCA4 MAL SLC17A4 GDPD2 TNXB

1.30e-051727855d654dd030ed22a701e15c5f09002951d99a52e8
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors|lymph-node_spleen / Manually curated celltypes from each tissue

ABO NYNRIN DYTN GLRB NPW

1.37e-051747856d9bdf4d28ff8ebb66ffd1ccdd6a4fe9440a83f3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PWWP2A CLCA4 FAT2 GIGYF2 TNXB

1.41e-0517578565571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3C2B TMEM31 NPC1L1 MFSD2B IL18BP

1.57e-05179785d2db9e70b780643f1e004c41a70464d0abe26088
ToppCellTCGA-Colorectal-Solid_Tissue_Normal|TCGA-Colorectal / Sample_Type by Project: Shred V9

CLCA4 MAL SLC17A4 GDPD2 TNXB

1.66e-0518178588f6f56f5f58b479d5db91b32c45934c045f88ea
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

MROH6 PIK3C2B FA2H MUC16 FUT3

1.75e-0518378515d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLCA4 FAT2 LRRC26 GDPD2 FFAR4

1.94e-05187785380c3e0bc73b266718893a3b3ca207ce5fd31883
ToppCelldroplet-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA4 FAT2 LRRC26 GDPD2 FFAR4

1.94e-051877855b3c3c6421efd25c740ae121968b5520bbdc07b2
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLCA4 FAT2 LRRC26 GDPD2 FFAR4

1.94e-05187785796046ff066a9c3847faa9bf1f8beccd956c01f7
ToppCellfacs-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA4 FAT2 LMO7 LRRC26 GDPD2

1.94e-05187785fe9fc21192ede2eea61f419d20ccda254569d0a6
ToppCelldroplet-Trachea-3m-Epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAT2 MAL LRRC26 GDPD2 FFAR4

2.10e-051907850114cf48612d78c3ada4d8a05850501fef6892c5
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAT2 MAL LRRC26 GDPD2 FFAR4

2.10e-0519078501e7747547ea1f3049a11a1717565ba71dd52bdc
ToppCelldroplet-Trachea-nan-3m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT2 MAL LRRC26 GDPD2 FFAR4

2.10e-05190785e647f9a2dcf7f2dffef53c45bbe171416518fd59
ToppCelldroplet-Trachea-nan-3m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT2 MAL LRRC26 GDPD2 FFAR4

2.10e-05190785434de72dde09644efbddcaa643a4a3eaf5f643bf
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLCA4 FAT2 FA2H UGT2A1 GPR151

2.15e-051917850f9443da0f73d07456142fae08b2dc92a5b7b592
ToppCellCOPD-Epithelial-Goblet|COPD / Disease state, Lineage and Cell class

LMO7 FA2H LRRC26 MUC16 FUT3

2.20e-0519278593b2ca0a97776d28c7e8f1a0642c4b63a5554aab
ToppCellfacs-Trachea-nan-3m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA4 FAT2 MAL LMO7 LRRC26

2.32e-051947853701ca87c6dc9ccd7b4146e56371546174d26c36
ToppCellfacs-Trachea-nan-3m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA4 FAT2 MAL LMO7 LRRC26

2.32e-0519478565f9bf126be26114c2c3f4c46d48318986212a92
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LMO7 UGT2A1 SCNN1G MUC16 FUT3

2.43e-05196785c18874f37b90e6afacc562b2082b67ea8a7cb4a4
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLCA4 LMO7 FA2H MUC16 FUT3

2.43e-05196785a52879a4c822c5e4be569f01f845a795e00c5f4b
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLCA4 LMO7 FA2H MUC16 FUT3

2.43e-051967857a4d502550e9e37dc42f2ff1be3c896afe365d7f
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLCA4 LMO7 FA2H MUC16 FUT3

2.43e-0519678560ea673ed887fe3890c5cf4ff4165384b76d7361
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LMF2 SLC22A16 RELT FFAR4 FANCA

2.49e-05197785d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_basal-Suprabasal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CLCA4 FAT2 UGT2A1 SCNN1G MUC16

2.55e-05198785de5987588b9fa9ee8c595ba06d7d844ead0e3c74
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAL NYNRIN LRRC26 SCNN1G MUC16

2.55e-05198785dd0465b45b02cb8edf0914d19afb52fcaaeb012c
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CLCA4 UGT2A1 LRRC26 SCNN1G MUC16

2.55e-051987855dd2aa7684c36beffa204ca4c04d0501cabac10f
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SULT2A1 NPC1L1 CYP4F2 CYP4F12 DNASE1

2.55e-051987856e6af8fad09f8e48b3f2ce463d5773b6a69864d1
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CLCA4 LMO7 UGT2A1 MUC16 FUT3

2.61e-05199785d04062d86643e5712cc2f519f4f36e643d404a16
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CLCA4 LMO7 UGT2A1 MUC16 FUT3

2.61e-05199785a3f83fe5c3c557cd3ef8f5632f7fba5cf1859937
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CLCA4 UGT2A1 LRRC26 MUC16 FUT3

2.61e-05199785ec1e110671e7725f752163c7241dbbf638dec2b2
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CLCA4 LMO7 UGT2A1 MUC16 FUT3

2.61e-05199785644197ff7e3299587881dd678836262e670ed4a8
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLCA4 FAT2 UGT2A1 LRRC26 CYP4F12

2.61e-05199785fbd39d34636137d1b877dd8815d58f124990136b
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LMO7 FA2H UGT2A1 MUC16 FUT3

2.61e-051997857223f853335492ca617dbec3e4b6872a8a463a45
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LMO7 FA2H UGT2A1 MUC16 FUT3

2.61e-05199785e03bdc7cb825e287f41b834ec6061d23c1c03b04
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLCA4 FAT2 UGT2A1 LRRC26 CYP4F12

2.61e-051997856977f939ddbc47d4921f36c0a61a205259fe1284
ToppCellBiopsy_IPF-Epithelial-MUC5AC+_High|Biopsy_IPF / Sample group, Lineage and Cell type

UGT2A1 SCNN1G MUC16 CYP4F12 FUT3

2.61e-0519978551cb306e36537a53968c55187bd87c83e1706187
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SULT2A1 NPC1L1 CYP4F2 CYP4F12 DNASE1

2.61e-0519978501c2721bc82cd672e9477029b4a7ecc77e2f1b00
ToppCellSevere_COVID-19-Epithelial-Basal/Club|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

CLCA4 LMO7 UGT2A1 MUC16 FUT3

2.61e-051997852a0aebcfadff4e2dfc8244ad8a87c338ecccacfd
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CLCA4 LMO7 UGT2A1 MUC16 FUT3

2.61e-05199785fd364f43859b2e7a3e91ce6a1c430cc42ad26a49
ToppCellBronchus_Control_(B.)-Epithelial-TX-Club|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

SLC17A9 LRRC26 SCNN1G MUC16 FUT3

2.68e-05200785292c63693eb7f435335a8cfba07aa35b72139393
ToppCellLPS_IL1RA-Endothelial-Endothelial-Artery|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CLCA4 SLC22A16 PIK3C2B NPW TRDN

2.68e-05200785ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLCA4 LMO7 UGT2A1 MUC16 CYP4F12

2.68e-05200785b68d212159b9d04866ba02ff55c35be247805eec
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

UGT2A1 LRRC26 SCNN1G MUC16 FUT3

2.68e-05200785133853d0f55c63ebe94dd54151f9f1f90650a0d8
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Stem_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

FAHD2B MAL DCDC1 TRDN

4.99e-05115784f3062a7247b376e9978dc01109fb94d6dd960052
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Col27a1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MROH6 NPC1L1 NPW

5.88e-054378352772889cdf2e47f703f1d6418da3dc9e5f7d933
ToppCellfacs-MAT-Fat-18m-Epithelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA4 FA2H SLC17A4 TRDN

1.19e-0414478465ffd8a1620b178d995fe8c913871f0b376b896f
ToppCellfacs-MAT-Fat-18m-Epithelial-epithelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA4 FA2H SLC17A4 TRDN

1.19e-04144784fd852095dcd716ac53b0fd25d83e6f454b2ae794
ToppCellfacs-MAT-Fat-18m-Epithelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA4 FA2H SLC17A4 TRDN

1.19e-04144784e4e148007c772cd163a34fb172e05184f7352a2b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT2 SLC17A9 TRDN FANCA

1.40e-041507847a9d6a7ff8000e9a061e1b586e4c258cc91a2a09
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT2 SLC17A9 TRDN FANCA

1.40e-04150784e5b843cb2bc847f6cab4cbec0a2a6a72fac50fee
ToppCell18-Airway-Epithelial-Goblet-like_secretory|Airway / Age, Tissue, Lineage and Cell class

CLCA4 LRRC26 FUT3 EME2

1.51e-0415378414a60220e169ce642771636de982a7b02e5b2608
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Pcdh11x_(Neuron.Gad1Gad2.Synpr-Pcdh11x)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NPW TSSK3 FANCA

1.52e-0459783439a9d56eeecccd70a4defb430e228329655cb80
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Pcdh11x_(Neuron.Gad1Gad2.Synpr-Pcdh11x)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NPW TSSK3 FANCA

1.52e-045978350432c7b52fd197e8856ba0296c34cf66a2faaf5
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC22A8 UGT2A1 SLC17A4 CYP4F2

1.55e-0415478489a60a79d07466d7ad05888d10a72d3b1ab384af
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC22A8 UGT2A1 SLC17A4 CYP4F2

1.55e-04154784f1fea1a87e977221fa125b62287368be9af4987d
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT1_Precursor|E16.5-samps / Age Group, Lineage, Cell class and subclass

LMO7 LRRC26 SCNN1G FFAR4

1.55e-041547848a643d91896af9b630a715fb284c1523d01ad1a3
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC22A8 UGT2A1 SLC17A4 CYP4F2

1.55e-04154784b5604c0b0b9b283352a3f612f40883b9123475d1
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC22A8 UGT2A1 SLC17A4 CYP4F2

1.55e-04154784160b170a3ade8b246843c9854af332475c047ba0
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Crh_(MGE-derived_cortical_interneurons--Martinotti_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GPR152 NPW DNASE1

1.68e-0461783351078cb41e285af7e117820ee607d4c24332a9d
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Crh_(MGE-derived_cortical_interneurons--Martinotti_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GPR152 NPW DNASE1

1.68e-0461783aae9ba2240812258d1c9e0e443d4f817b4796131
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLCA4 LMO7 TAS1R1 MUC16

1.75e-0415978460b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Crim1_(Neuron.Gad1Gad2.Cplx3-Crim1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GDPD2 GPR101 GPR151

1.76e-046278391c49ae176d2a418a58398e9d5e55c77187cc2fb
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Crim1_(Neuron.Gad1Gad2.Cplx3-Crim1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GDPD2 GPR101 GPR151

1.76e-04627833275775572a65460b6248ee72b4c85e4d4dee424
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFSF13 NYNRIN LRRC26 TSSK3

1.88e-041627843dc39db0d5f6f3d7bcc312a6bce7aaeb914138d1
ToppCellfacs-Thymus-Epithelium-3m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFSF13 NYNRIN LRRC26 TSSK3

1.88e-041627840a7138266054ea5954649c8b61ef93905d56b068
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FA2H SCNN1G MUC16 FUT3

1.88e-04162784112fa4de685727f6c8bf6fc4afb82de0524070ad
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFSF13 NYNRIN LRRC26 TSSK3

1.88e-0416278425323785dd33337bcefd05958a4a1a208a9ceb04
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue-6|TCGA-Colorectal / Sample_Type by Project: Shred V9

CLCA4 SLC17A4 GDPD2 TNXB

1.88e-041627847f9385aa749bfb2fa9fee6939fe46d946bc21d31
ToppCellIIF-Other-HSPC|IIF / Disease, Lineage and Cell Type

NYNRIN DYTN IGDCC3 CYP4F2

1.92e-041637841e0d38fbed38ac48478868a1480172a1a3f7c1b7
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

IARS2 DSTYK GIGYF2 TSSK3

2.06e-0416678432d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-club_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SULT2A1 LRRC26 SCNN1G FFAR4

2.26e-041707846de3778e8257c3330db0780c59238ca501fe5059
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-club_cell-club_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SULT2A1 LRRC26 SCNN1G FFAR4

2.26e-0417078460887da674ef1a735bad618235608312d8de63d3
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAL FA2H SLC17A4 GDPD2

2.31e-041717845d0d6c1ff610a703ae0b834a12823c5ff9012932
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_Erythro-Mega|lymph-node_spleen / Manually curated celltypes from each tissue

ABO DYTN GLRB NPW

2.31e-041717843ecd0a074344179c57eb2d9a857ba594904d00fa
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Tac1_(Substantia_Innominata_(SI))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FAT2 LRRC26 GPR152

2.32e-0468783506a7727f281136f5f6e397af99c219854a01e26
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Tac1_(Substantia_Innominata_(SI))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FAT2 LRRC26 GPR152

2.32e-0468783a5528ececdfa798ecc939482ee80a963dcc3c429
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Tac1_(Substantia_Innominata_(SI))--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FAT2 LRRC26 GPR152

2.32e-04687834a4bd488ab6dfae61e654e42bf374382bccb66cc
ToppCell390C-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CLCA4 FAT2 TMEM158 NPW

2.36e-04172784bb542f6ca4eb8167129bc84ca1160a54fbb68731
ToppCell390C-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CLCA4 FAT2 TMEM158 NPW

2.36e-04172784aff37b9689b0d30ee7097d997d9588efc475c8fd
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABO NPC1L1 LRRC26 GPR101

2.47e-04174784e7cca4b6a3935fad61cf2a3d9984ab1ffa1a9447
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM94 GDPD2 GPR151 FANCA

2.47e-04174784f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABO NPC1L1 LRRC26 GPR101

2.47e-04174784ad5b56f0ace6455c033834b931ec870cc0dc9290
Diseaseserum carcinoembryonic antigen measurement

ABO FUT3 FUT5

1.54e-0520723EFO_0005760
Diseasetotal campesterol measurement

ABO NPC1L1

1.76e-053722EFO_0020962
DiseaseVesico-Ureteral Reflux

DSTYK TNXB

3.51e-054722C0042580
Diseasealpha-(1;3)-fucosyltransferase 5 measurement

FUT3 FUT5

3.51e-054722EFO_0021979
Diseasedesmoglein-2 measurement

ABO FUT3

5.84e-055722EFO_0020322
Diseasenon-high density lipoprotein cholesterol measurement

BMPR2 ABO DSTYK NYNRIN NPC1L1 PEX6 CYP4F12 FUT3 SLC33A1

5.84e-05713729EFO_0005689
Diseaselithostathine-1-alpha measurement

ABO FUT3

1.22e-047722EFO_0801083
Diseaseperipheral vascular disease

ABO SULT2A1

1.22e-047722EFO_0003875
Diseasegalactoside 3(4)-L-fucosyltransferase measurement

FUT3 FUT5

1.22e-047722EFO_0021853
Diseaseprotein FAM3B measurement

ABO FUT3

1.22e-047722EFO_0021857
Diseasealpha-(1,3)-fucosyltransferase 5 measurement

FUT3 FUT5

1.22e-047722EFO_0020136
DiseaseCystic Fibrosis

CLCA4 SCNN1G

3.18e-0411722C0010674
Diseaseovarian cancer (is_implicated_in)

ITGA8 MUC16 FANCA

3.52e-0456723DOID:2394 (is_implicated_in)
Diseasemetabolite measurement

ABO SULT2A1 FA2H SLC17A4 CYP4F2 FUT3 SLC12A5

4.33e-04560727EFO_0004725
Diseasecancer biomarker measurement

ABO FUT3

6.04e-0415722EFO_0005127
Diseaselevel of Sterol ester (27:1/18:0) in blood serum

ABO NPC1L1

6.89e-0416722OBA_2045196
Diseaseoleoylcarnitine measurement

SLC22A16 LMO7

9.77e-0419722EFO_0021043
Diseaseandrosterone glucuronide measurement

SLC22A8 SULT2A1

1.08e-0320722EFO_0800317
Diseasee-selectin measurement

ABO FUT3

1.31e-0322722EFO_0004575
Diseasecholelithiasis

ABO SULT2A1 FUT3

1.32e-0388723EFO_0004799
Diseasegallstones

ABO SULT2A1 FUT3

2.37e-03108723EFO_0004210
Diseaseremnant cholesterol measurement

ABO NYNRIN NPC1L1

2.37e-03108723EFO_0010815

Protein segments in the cluster

PeptideGeneStartEntry
LDPIISSNPLLRWWA

nan

111

A8MVM7
NWPSTVALWLVDPLT

SLC33A1

461

O00400
VVTPWLAPIVWEGTF

ABO

86

P16442
WDFQSWVPLLSRILP

ANKRD13C

231

Q8N6S4
WLWDLTTSLPTTTWP

MUC16

2051

Q8WXI7
APSILWPVASVWLIT

DCDC1

691

M0R2J8
VLGSSSLQLLWEPWP

IGDCC3

531

Q8IVU1
EAPLLLPSWVQELWE

NPW

86

Q8N729
NWTPDLSPLWVLLLC

IL18BP

6

O95998
LIWPTIPGEISWDVS

FFAR4

196

Q5NUL3
LSASVRLHIEWIPWP

FAT2

1326

Q9NYQ8
APSWWTLPLIAVYLL

OR51S1

31

Q8NGJ8
LSPVPWLPSEESTLW

PEX6

416

Q13608
DLPVPTISAPSRWVW

LMO7

1211

Q8WWI1
WVLATLFSVPWLVFP

GPR152

156

Q8TDT2
LVSAVLSTPLWEWVL

MFSD2B

326

A6NFX1
PIWLITPQTYLIIWV

GDPD2

481

Q9HCC8
PTLLIVVLSWLSFWI

GLRB

276

P48167
LLTWQGDPEPTVRWL

MROH6

406

A6NGR9
WIVAILQSTPPLYGW

GPR101

156

Q96P66
AWPSVLVQPAPSAIW

POM121L12

251

Q8N7R1
IWTVASLLPLPEWFF

GPR151

161

Q8TDV0
RITWVSPPAITLEWK

DSTYK

551

Q6XUX3
WATPNVSFSIPLWVI

ITGA8

1001

P53708
EWPSLTAQWLPDVTR

RBBP4

41

Q09028
WPSLTVQWLPEVTKP

RBBP7

41

Q16576
SSLPLVLASAPSWEW

PIK3C2B

851

O00750
TWVASWPLTILVLSV

NPC1L1

346

Q9UHC9
SVPIIWVPLVLYLSW

FA2H

171

Q7L5A8
RAQWLTPVIPALWEA

ZNF561-AS1

16

K7EIQ3
WCPVEISKTVLWPES

IL4R

341

P24394
VFTPYWPVTVLILTW

AWAT2

41

Q6E213
IWELQPTASQPTVWE

GIGYF2

691

Q6Y7W6
LPWSEVTFLAPVTWP

FAHD2B

91

Q6P2I3
FLSWVQSEPPILLWL

DYTN

196

A2CJ06
IRLWTSPTFQWLIPD

DNASE1

206

P24855
TKCPLILTSALVWWP

FANCA

1161

O15360
ILTSALVWWPSLEPV

FANCA

1166

O15360
TSPWLLLLLVVGSWL

CYP4F12

16

Q9HCS2
VPWLPWTILLVSTAA

BMPR2

11

Q13873
PWLWVVYILTVALPV

CANX

481

P27824
LWPVAASPWLLLLLV

CYP4F2

11

P78329
LVWILVASSLVPWPL

MAL

36

P21145
VASSLVPWPLVQGWV

MAL

41

P21145
VQWVELLPDTQTPSW

DYNC1H1

4306

Q14204
ILSTAWILWSPSDIL

SELENOI

271

Q9C0D9
WILWSPSDILELHPR

SELENOI

276

Q9C0D9
WVPWISPETTARPHL

EME2

166

A4GXA9
WQSPLTTWIIPFISP

ERVFC1

511

P60507
AIPQWRWLQLTVSIP

SLC22A8

231

Q8TCC7
SIWVKWAPPLERSQL

SLC17A4

186

Q9Y2C5
WPSVVSEKWLLPVLT

SCNN1G

471

P51170
VIESPWPLRSTAPWS

NYNRIN

1601

Q9P2P1
NLVVGTLAWPSPWVI

SLC12A5

496

Q9H2X9
SRTWNKLTWLTPLIP

MT-ND2

231

P03891
TTPTRPTLLILLWTW

FUT3

56

P21217
LLWTWPFHIPVALSR

FUT3

66

P21217
LLILLWTWPFNTPVA

FUT5

76

Q11128
SESPGFIPLLWWLLS

HSF2BP

251

O75031
FPWWPARILTITVSR

PWWP2A

666

Q96N64
LPEWTAWLILAVISV

PSEN1

241

P49768
QLWETPTLLWEAPRL

LMF2

56

Q9BU23
WVLPETPFWLLSEGR

SLC22A16

286

Q86VW1
WIILLSTIALGWTTP

SLITRK3

16

O94933
WIFNVVPWLVAIPAS

SLC17A9

276

Q9BYT1
PVSILVWTTQPWTIP

IARS2

291

Q9NSE4
IQSVPIWERSPWVES

SULT2A1

66

Q06520
ITWNSLPPSISLWDP

CLCA4

521

Q14CN2
WLSPWLLLALTPLLS

RHBDD3

146

Q9Y3P4
RTINLLEVLPWPTEW

TMEM31

66

Q5JXX7
WLPLLLTWLTPEVNS

WNT2

11

P09544
LLICLTWLVVWTPLP

TAS1R1

691

Q7RTX1
KSPLTNLWWAVTVPV

TMEM94

1261

Q12767
WSVAALIWPVPIIAG

TMEM158

236

Q8WZ71
ILRPSIEEVSWHPWL

TSSK3

251

Q96PN8
WVTDPTPDSLRLSWT

TNXB

1681

P22105
LVITPQWRWIPSKTP

ZNF516-DT

36

Q6ZTR6
VVWTPIPVLTWFFPI

TMEM222

56

Q9H0R3
HAITLPWESLWTPRL

ZACN

106

Q401N2
PWESLWTPRLTILEA

ZACN

111

Q401N2
LLPWPLATLTSTTLW

RELT

16

Q969Z4
LRPISPWRWLFSVVV

TMEM19

46

Q96HH6
SPAAWLLVIALIITW

TRDN

46

Q13061
VLTWLENRPSPSTIW

UGT2A1

91

P0DTE4
LSLPFWVWTVIFLVP

TMEM251

96

Q8N6I4
PVREPALSVALWLSW

TNFSF13

21

O75888
LLLLSPWPVWAQVSA

LRRC26

16

Q2I0M4