Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

KCNJ6 SCN10A RIMBP2

7.64e-0517993GO:0099508
GeneOntologyBiologicalProcessalternative mRNA splicing, via spliceosome

RBM15 SRSF6 SFSWAP TRA2B SRRM4 RBM20

2.07e-0679986GO:0000380
GeneOntologyBiologicalProcessregulation of alternative mRNA splicing, via spliceosome

RBM15 SRSF6 TRA2B SRRM4 RBM20

8.93e-0659985GO:0000381
GeneOntologyBiologicalProcessregulation of mRNA processing

RBM15 SRSF6 SFSWAP TRA2B SRRM4 RBM20 FIP1L1

1.05e-05158987GO:0050684
GeneOntologyBiologicalProcessregulation of mRNA splicing, via spliceosome

RBM15 SRSF6 SFSWAP TRA2B SRRM4 RBM20

3.50e-05129986GO:0048024
GeneOntologyBiologicalProcessregionalization

MYF6 TDRKH TRA2B HELT EDN1 VANGL2 CYP26C1 DNAI2 PRKDC NOTCH2

9.21e-054789810GO:0003002
DomainDUF3338

FRMD4B FRMD4A

1.62e-044982PF11819
DomainDUF3338

FRMD4B FRMD4A

1.62e-044982IPR021774
DomainFERM_C

FRMPD2 FRMD4B FRMD4A

3.34e-0426983PF09380
DomainFERM_C

FRMPD2 FRMD4B FRMD4A

3.74e-0427983SM01196
DomainFERM_PH-like_C

FRMPD2 FRMD4B FRMD4A

3.74e-0427983IPR018980
DomainFERM_N

FRMPD2 FRMD4B FRMD4A

6.82e-0433983PF09379
DomainFERM_N

FRMPD2 FRMD4B FRMD4A

6.82e-0433983IPR018979
DomainPDZ

MAGI1 SYNPO2 FRMPD2 SHANK3 GRID2IP

8.84e-04141985PF00595
DomainPDZ

MAGI1 SYNPO2 FRMPD2 SHANK3 GRID2IP

1.10e-03148985SM00228
Domain-

MAGI1 SYNPO2 FRMPD2 SHANK3 GRID2IP

1.17e-031509852.30.42.10
DomainPDZ

MAGI1 SYNPO2 FRMPD2 SHANK3 GRID2IP

1.20e-03151985PS50106
DomainPDZ

MAGI1 SYNPO2 FRMPD2 SHANK3 GRID2IP

1.24e-03152985IPR001478
DomainRRM_dom

RBM15 SRSF6 TRA2B RBM20 PPARGC1B NXF1

1.25e-03227986IPR000504
DomainRRM

RBM15 SRSF6 TRA2B RBM20 PPARGC1B NXF1

1.34e-03230986PS50102
DomainLRRcap

CEP72 NXF1

1.45e-0311982SM00446
DomainU2A'_phosphoprotein32A_C

CEP72 NXF1

1.45e-0311982IPR003603
DomainZnf_C2H2_matrin

ZNF318 RBM20

1.74e-0312982IPR000690
DomainFERM_M

FRMPD2 FRMD4B FRMD4A

1.81e-0346983PF00373
Domain-

RBM15 SRSF6 TRA2B RBM20 PPARGC1B NXF1

1.81e-032449863.30.70.330
Domain-

FRMPD2 FRMD4B FRMD4A

2.17e-03499831.20.80.10
DomainFERM_central

FRMPD2 FRMD4B FRMD4A

2.17e-0349983IPR019748
DomainFERM_domain

FRMPD2 FRMD4B FRMD4A

2.17e-0349983IPR000299
DomainFERM_1

FRMPD2 FRMD4B FRMD4A

2.30e-0350983PS00660
DomainFERM_2

FRMPD2 FRMD4B FRMD4A

2.30e-0350983PS00661
DomainFERM_3

FRMPD2 FRMD4B FRMD4A

2.30e-0350983PS50057
DomainBand_41_domain

FRMPD2 FRMD4B FRMD4A

2.30e-0350983IPR019749
DomainB41

FRMPD2 FRMD4B FRMD4A

2.30e-0350983SM00295
DomainFERM/acyl-CoA-bd_prot_3-hlx

FRMPD2 FRMD4B FRMD4A

2.30e-0350983IPR014352
DomainNucleotide-bd_a/b_plait

RBM15 SRSF6 TRA2B RBM20 PPARGC1B NXF1

2.39e-03258986IPR012677
DomainZF_MATRIN

ZNF318 RBM20

3.95e-0318982PS50171
DomainEz/rad/moesin-like

FRMD4B FRMD4A

5.36e-0321982IPR000798
DomainRRM

RBM15 SRSF6 TRA2B RBM20 PPARGC1B

5.73e-03217985SM00360
DomainFERM_CS

FRMD4B FRMD4A

6.98e-0324982IPR019747
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

FLII RBM15 SRSF6 SFSWAP XPC ZNF318 ZFPM1 PNISR PPIG ZNF516 TMPO FIP1L1 PRKDC TOPORS NOTCH2

7.19e-097741011515302935
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

RBM15 SRSF6 TRA2B IP6K1 PNISR SBK1 PPIG TMPO FIP1L1 PRKDC NXF1

8.94e-093611011126167880
Pubmed

Allelic polymorphism synergizes with variable gene content to individualize human KIR genotype.

KIR3DL1 KIR3DL2 KIR3DS1

2.38e-083101311859120
Pubmed

Analysis of killer immunoglobulin-like receptor genes in ankylosing spondylitis.

KIR3DL1 KIR3DL2 KIR3DS1

2.38e-083101319019897
Pubmed

Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1.

KIR3DL1 KIR3DL2 KIR3DS1

9.49e-084101327455421
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

RBM15 RPL36 SRSF6 SFSWAP TRA2B AHCTF1 XPC ZNF318 ZBTB7B PNISR CREM PPIG TMPO FIP1L1 PRKDC NXF1 KDM1A

1.89e-0712941011730804502
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

RBM15 RPL36 SRSF6 SFSWAP TRA2B BMS1 XPC PNISR VANGL2 PPIG KCTD10 TMPO FIP1L1 PRKDC NXF1

5.50e-0710821011538697112
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

RBM15 SFSWAP TRA2B XPC PNISR PPIG FIP1L1 PRKDC

7.46e-07251101831076518
Pubmed

SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.

RPL36 SRSF6 TRA2B AHCTF1 BMS1 PPIG FIP1L1 PRKDC

9.44e-07259101830404004
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

FLII RBM15 RPL36 SRSF6 TRA2B AHCTF1 ZNF318 TMPO FIP1L1

1.14e-06361101930344098
Pubmed

Human diversity in killer cell inhibitory receptor genes.

KIR3DL1 KIR3DL2 KIR3DS1

1.32e-06810139430221
Pubmed

Alternatively spliced forms of human killer inhibitory receptors.

KIR3DL1 KIR3DL2 KIR3DS1

1.97e-06910138662091
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

RBM15 TRA2B AHCTF1 ZFPM1 PPIG TMPO PRKDC TOPORS KDM1A

3.30e-06411101935182466
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

BRPF3 SZT2 SRRM4 BMS1 FRMD4B VANGL2 ZNF516 IGSF9 KDM1A SMG6

3.39e-065291011014621295
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FLII HIVEP2 RHBDF1 SZT2 ZFPM1 WNK1 CDR2L SGSM2 KANK3 ZNF516 MAP3K11 PRKDC NOTCH2 SMG6

3.86e-0611051011435748872
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia].

KIR3DL1 KIR3DL2 KIR3DS1

5.13e-0612101317490516
Pubmed

[Relationship between CMV reactivation and KIR haplotype/HLA-Cw genotype in patients after unrelated-donor hematopoietic stem cell transplantation.].

KIR3DL1 KIR3DL2 KIR3DS1

5.13e-0612101320137308
Pubmed

Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.

FLII RBM15 SRSF6 TRA2B AHCTF1 BMS1 TMPO FIP1L1 PRKDC

5.83e-06441101931239290
Pubmed

A method for killer-cell immunoglobulin-like receptor (KIR) 3DL1/3DS1 genotyping using DNA recovered from frozen plasma.

KIR3DL1 KIR3DS1

8.35e-062101223524032
Pubmed

Diversity of the p70 killer cell inhibitory receptor (KIR3DL) family members in a single individual.

KIR3DL1 KIR3DL2

8.35e-062101210774747
Pubmed

Endothelin 1, NF-κB, and ADAM-15 expression in diabetic foot wounds.

ADAM15 EDN1

8.35e-062101230685994
Pubmed

MHC-mismatched islet allografts are vulnerable to autoimmune recognition in vivo.

CIITA PRKDC

8.35e-062101216081800
Pubmed

Allele diversity of the killer cell immunoglobulin-like receptors KIR3DL1/S1 and the combination with their HLA ligands in Mexican Mestizos from Mexico City.

KIR3DL1 KIR3DS1

8.35e-062101230365992
Pubmed

No association of KIR3DL1 or KIR3DS1 or their alleles with ankylosing spondylitis.

KIR3DL1 KIR3DS1

8.35e-062101219874556
Pubmed

Functional polymorphism of the KIR3DL1/S1 receptor on human NK cells.

KIR3DL1 KIR3DS1

8.35e-062101217182560
Pubmed

Evaluation of KIR3DL1/KIR3DS1 polymorphism in Behçet's disease.

KIR3DL1 KIR3DS1

8.35e-062101227708262
Pubmed

Genetic control of variegated KIR gene expression: polymorphisms of the bi-directional KIR3DL1 promoter are associated with distinct frequencies of gene expression.

KIR3DL1 KIR3DS1

8.35e-062101219008943
Pubmed

Different NK cell surface phenotypes defined by the DX9 antibody are due to KIR3DL1 gene polymorphism.

KIR3DL1 KIR3DL2

8.35e-062101211207248
Pubmed

Investigation of killer cell immunoglobulin-like receptor gene diversity in KIR3DL1 and KIR3DS1 in a transplant population.

KIR3DL1 KIR3DS1

8.35e-062101218331531
Pubmed

Contribution of KIR3DL1/3DS1 to ankylosing spondylitis in human leukocyte antigen-B27 Caucasian populations.

KIR3DL1 KIR3DS1

8.35e-062101216805919
Pubmed

HLA class I subtype-dependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection.

KIR3DL1 KIR3DS1

8.35e-062101219386717
Pubmed

Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4.

SRRM4 KDM1A

8.35e-062101232403054
Pubmed

DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina.

ZBTB7B TMPO

8.35e-062101222726435
Pubmed

Role of natural killer cells in a cohort of elite suppressors: low frequency of the protective KIR3DS1 allele and limited inhibition of human immunodeficiency virus type 1 replication in vitro.

KIR3DL1 KIR3DS1

8.35e-062101219211742
Pubmed

Putative role of KIR3DL1/3DS1 alleles and HLA-Bw4 ligands with end stage renal disease and long term renal allograft survival.

KIR3DL1 KIR3DS1

8.35e-062101228942035
Pubmed

The profile of KIR3DL1 and KIR3DS1 alleles in an African American population resembles that found in African populations.

KIR3DL1 KIR3DS1

8.35e-062101220230527
Pubmed

Allele imputation for the killer cell immunoglobulin-like receptor KIR3DL1/S1.

KIR3DL1 KIR3DS1

8.35e-062101235192601
Pubmed

Development of a PCR-SSOP approach capable of defining the natural killer cell inhibitory receptor (KIR) gene sequence repertoires.

KIR3DL1 KIR3DS1

8.35e-062101211098931
Pubmed

Evaluation of KIR3DL1/KIR3DS1 allelic polymorphisms in Kenyan children with endemic Burkitt lymphoma.

KIR3DL1 KIR3DS1

8.35e-062101237647275
Pubmed

Association of the KIR3DS1*013 and KIR3DL1*004 alleles with susceptibility to ankylosing spondylitis.

KIR3DL1 KIR3DS1

8.35e-062101220131260
Pubmed

Solution structures of the SH3 domains from Shank scaffold proteins and their interactions with Cav1.3 calcium channels.

CACNA1D SHANK3

8.35e-062101230058071
Pubmed

SHANK3 Deficiency Impairs Heat Hyperalgesia and TRPV1 Signaling in Primary Sensory Neurons.

SHANK3 SCN10A

8.35e-062101227916453
Pubmed

Protective genotypes in HIV infection reflect superior function of KIR3DS1+ over KIR3DL1+ CD8+ T cells.

KIR3DL1 KIR3DS1

8.35e-062101225112829
Pubmed

Unusual selection on the KIR3DL1/S1 natural killer cell receptor in Africans.

KIR3DL1 KIR3DS1

8.35e-062101217694054
Pubmed

Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes.

KIR3DL1 KIR3DS1

8.35e-062101219411600
Pubmed

Contribution of functional KIR3DL1 to ankylosing spondylitis.

KIR3DL1 KIR3DS1

8.35e-062101220818412
Pubmed

Human transformer 2beta and SRp55 interact with a calcitonin-specific splice enhancer.

SRSF6 TRA2B

8.35e-062101212531473
Pubmed

KIR3DL1 and KIR3DL2 gene copy number variation in axial spondyloarthritis.

KIR3DL1 KIR3DL2

8.35e-062101225940819
Pubmed

Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer.

KIR3DL1 KIR3DL2

8.35e-06210128777725
Pubmed

Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.

KIR3DL1 KIR3DL2 KIR3DS1

8.45e-0614101319875891
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.

KIR3DL1 KIR3DL2 KIR3DS1

8.45e-0614101315896204
Pubmed

[Genotype and haplotype analysis of killer cell immunoglobulin-like receptors in ankylosing spondylitis].

KIR3DL1 KIR3DL2 KIR3DS1

8.45e-0614101319489269
Pubmed

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.

KIR3DL1 KIR3DL2 KIR3DS1

8.45e-0614101318945962
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.

KIR3DL1 KIR3DL2 KIR3DS1

1.05e-0515101320082646
Pubmed

Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.

KIR3DL1 KIR3DL2 KIR3DS1

1.05e-0515101319926642
Pubmed

[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].

KIR3DL1 KIR3DL2 KIR3DS1

1.05e-0515101320356536
Pubmed

Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.

KIR3DL1 KIR3DL2 KIR3DS1

1.05e-0515101320643584
Pubmed

Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.

KIR3DL1 KIR3DL2 KIR3DS1

1.05e-0515101319326408
Pubmed

Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.

KIR3DL1 KIR3DL2 KIR3DS1

1.30e-0516101319897003
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.

KIR3DL1 KIR3DL2 KIR3DS1

1.30e-0516101319000141
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.

KIR3DL1 KIR3DL2 KIR3DS1

1.30e-0516101320670355
Pubmed

Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.

KIR3DL1 KIR3DL2 KIR3DS1

1.30e-0516101319527230
Pubmed

Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.

KIR3DL1 KIR3DL2 KIR3DS1

1.30e-0516101320652381
Pubmed

Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore.

KIR3DL1 KIR3DL2 KIR3DS1

1.30e-0516101318668235
Pubmed

Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages.

KIR3DL1 KIR3DL2 KIR3DS1

1.30e-0516101319279038
Pubmed

No association of KIR genes with Behcet's disease.

KIR3DL1 KIR3DL2 KIR3DS1

1.30e-0516101317868255
Pubmed

A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris.

KIR3DL1 KIR3DL2 KIR3DS1

1.30e-0516101318643961
Pubmed

Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever.

KIR3DL1 KIR3DL2 KIR3DS1

1.30e-0516101319309280
Pubmed

Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.

KIR3DL1 KIR3DL2 KIR3DS1

1.30e-0516101320331834
Pubmed

HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop.

KIR3DL1 KIR3DL2 KIR3DS1

1.30e-0516101320210919
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

MAGI1 FLII RBM15 RPL36 SRSF6 TRA2B HMGCS1 PPIG TMPO FIP1L1 PRKDC TOPORS GPT2 KDM1A

1.51e-0512471011427684187
Pubmed

Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.

KIR3DL1 KIR3DL2 KIR3DS1

1.57e-0517101319032228
Pubmed

The role of killer immunoglobulin-like receptor haplotypes on the outcome of unrelated donor haematopoietic SCT for thalassaemia.

KIR3DL1 KIR3DL2 KIR3DS1

1.57e-0517101320173792
Pubmed

Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru.

KIR3DL1 KIR3DL2 KIR3DS1

1.57e-0517101320483367
Pubmed

[Effects of killer immunoglobulin-like receptor and human leukocyte antigen class I ligand on the prognosis of related donor hematopoietic stem cell transplantation].

KIR3DL1 KIR3DL2 KIR3DS1

1.57e-0517101319968064
Pubmed

[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].

KIR3DL1 KIR3DL2 KIR3DS1

1.57e-0517101319218127
Pubmed

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.

KIR3DL1 KIR3DL2 KIR3DS1

1.57e-0517101320878400
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.

KIR3DL1 KIR3DL2 KIR3DS1

1.57e-0517101320650299
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.

KIR3DL1 KIR3DL2 KIR3DS1

1.57e-0517101319450876
Pubmed

Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.

KIR3DL1 KIR3DL2 KIR3DS1

1.57e-0517101319761533
Pubmed

Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.

KIR3DL1 KIR3DL2 KIR3DS1

1.88e-0518101319630074
Pubmed

Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa.

KIR3DL1 KIR3DL2 KIR3DS1

1.88e-0518101320519398
Pubmed

Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians.

KIR3DL1 KIR3DL2 KIR3DS1

1.88e-0518101319046302
Pubmed

Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection.

KIR3DL1 KIR3DL2 KIR3DS1

1.88e-0518101319846535
Pubmed

Association of killer cell immunoglobulin-like receptors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diabetes.

KIR3DL1 KIR3DL2 KIR3DS1

1.88e-0518101320580654
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela.

KIR3DL1 KIR3DL2 KIR3DS1

1.88e-0518101320210918
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

FLII RBM15 TRA2B XPC WNK1 CEP72 ZNF516 CEP135 FIP1L1 KDM1A

1.90e-056451011025281560
Pubmed

KIR and HLA gene combinations in Vogt-Koyanagi-Harada disease.

KIR3DL1 KIR3DL2 KIR3DS1

2.23e-0519101318571006
Pubmed

Association between killer-cell immunoglobulin-like receptor genotypes and leprosy in Brazil.

KIR3DL1 KIR3DL2 KIR3DS1

2.23e-0519101318778326
Pubmed

Associations between genes for killer immunoglobulin-like receptors and their ligands in patients with solid tumors.

KIR3DL1 KIR3DL2 KIR3DS1

2.23e-0519101320600442
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Southern Brazilian population from the state of Paraná.

KIR3DL1 KIR3DL2 KIR3DS1

2.23e-0519101318848853
Pubmed

Splicing factor TRA2B is required for neural progenitor survival.

SRSF6 SFSWAP TRA2B

2.23e-0519101323818142
Pubmed

The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.

KIR3DL1 KIR3DL2

2.50e-05310128760804
Pubmed

Multiple copies of KIR 3DL/S1 and KIR 2DL4 genes identified in a number of individuals.

KIR3DL1 KIR3DS1

2.50e-053101212826375
Pubmed

Deficiency of transcription factor RelB perturbs myeloid and DC development by hematopoietic-extrinsic mechanisms.

CIITA NOTCH2

2.50e-053101228348230
Pubmed

KIR3DS1/L1 and HLA-Bw4-80I are associated with HIV disease progression among HIV typical progressors and long-term nonprogressors.

KIR3DL1 KIR3DS1

2.50e-053101224059286
Pubmed

Activating KIR/HLA-I combinations as a risk factor of adult B-ALL.

KIR3DL2 KIR3DS1

2.50e-053101238262874
Pubmed

DNA methylation maintains allele-specific KIR gene expression in human natural killer cells.

KIR3DL1 KIR3DL2

2.50e-053101212538663
Pubmed

Polymorphisms of DNA repair genes are risk factors for prostate cancer.

XPC PRKDC

2.50e-053101217196815
Pubmed

The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells.

PRKDC KDM1A

2.50e-053101222464800
InteractionRNPS1 interactions

RPL36 SRSF6 SFSWAP TRA2B SRRM4 XPC PNISR PPIG ZNF41 FIP1L1 TOPORS NXF1

1.17e-064259912int:RNPS1
InteractionCLK1 interactions

RBM15 SRSF6 TRA2B SRRM4 IP6K1 PPIG TMPO PRKDC

1.25e-05219998int:CLK1
Cytoband1q22-q23

VANGL2 IGSF9

3.68e-041310121q22-q23
Cytoband1p36.11

DHDDS MAP3K6 TENT5B

4.67e-046810131p36.11
Cytoband19q13.4

KIR3DL1 KIR3DL2 KIR3DS1

7.24e-0479101319q13.4
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR3DL1 KIR3DL2 KIR3DS1

4.54e-0518713620
GeneFamilyPDZ domain containing

MAGI1 SYNPO2 FRMPD2 SHANK3 GRID2IP

3.28e-041527151220
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

FRMPD2 FRMD4B FRMD4A

9.96e-04507131293
GeneFamilyRNA binding motif containing

RBM15 SRSF6 TRA2B RBM20 PPARGC1B

1.50e-03213715725
CoexpressionRICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP

SYNPO2 SRSF6 TRA2B AHCTF1 PNISR SBK1 FRMD4A TMPO

4.21e-062421008M904
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLII SZT2 DHDDS CDR2L KANK3 PLEKHA3 SMG6

2.21e-0718710073699d5e71d779da922920aa3160895db187bf81b
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLII SZT2 DHDDS CDR2L KANK3 PLEKHA3 SMG6

2.21e-071871007033ba52c0c2f9978784947098fa697368ae44834
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM15 VWA1 MAP3K6 SHANK3 CDR2L KANK3

2.21e-06168100637249f38f8f04ec5743097259de67b106ca2b02f
ToppCellILEUM-inflamed-(7)_CD36+_endothelial_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MAGI1 ADAM15 VWA1 EDN1 MGP KANK3

5.69e-06198100605d6558c7990ad2277db999025a073d29b273dfc
ToppCellILEUM-inflamed-(7)_ACKR1+_endothelial_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MAGI1 ADAM15 VWA1 EDN1 MGP KANK3

5.86e-0619910065c799115a6e95bcd896e4ad10bd272705c9a4e2c
ToppCellILEUM-inflamed-(7)_Endothelial_cell|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MAGI1 ADAM15 VWA1 EDN1 MGP KANK3

5.86e-06199100697052c28e354833901f28d339b09f97f50a5b752
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM15 VWA1 MAP3K6 SHANK3 MGP KANK3

5.86e-061991006e6715288a586631676722f2323f0d833431161cf
ToppCell367C-Endothelial_cells-Endothelial-A_(Artery)|367C / Donor, Lineage, Cell class and subclass (all cells)

MAGI1 ADAM15 VWA1 SHANK3 EDN1 KANK3

5.86e-06199100629ed081bd5204a32068b420f2244f3704891547b
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_venous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAM15 VWA1 SHANK3 EDN1 MGP KANK3

5.86e-0619910066fb81388c5045e81c3849a7136bdff3f953f044e
ToppCell367C-Endothelial_cells-Endothelial-A_(Artery)-|367C / Donor, Lineage, Cell class and subclass (all cells)

MAGI1 ADAM15 VWA1 SHANK3 EDN1 KANK3

5.86e-061991006c2d85f80037f209a4a329790f475d9f98f590262
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM15 VWA1 MAP3K6 SHANK3 MGP KANK3

6.03e-062001006ced14d83222dbebca85c40540e76824e683354f3
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4|Hippocampus / BrainAtlas - Mouse McCarroll V32

RPL36 TRA2B HELT IGSF9 NXF1

1.40e-0513610050185486c39700dd2f72d79be6d283494dd8379c9
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

RPL36 TRA2B HELT IGSF9 NXF1

1.40e-0513610053e13dc0634f3b05e9f9e6c3193f843f62e603b78
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 ARHGAP40 DAPK2 VANGL2 KCNJ6

2.97e-0515910058680b054622f573a82b1625fb93c2d5db81d1034
ToppCelldroplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAP3K6 CIITA ZNF516 CEP135 IL1RL1

3.55e-0516510051d0f60bf47a40ac916f0fcb5532a968742a0edbb
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SRRM4 VWA1 TENT5B KCNJ6 CYP26C1

4.57e-051741005b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SRRM4 VWA1 TENT5B KCNJ6 CYP26C1

4.57e-05174100571730503be3d9c839c4c9e950145e2101d682a1c
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SRRM4 VWA1 TENT5B KCNJ6 CYP26C1

4.57e-051741005ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SRRM4 VWA1 TENT5B KCNJ6 CYP26C1

4.57e-051741005cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYF6 ADAM15 SHANK3 KANK3 MAP3K11

4.57e-05174100542735f6a8e5ec36dd3d35aceea6d37cf3eaa1871
ToppCellwk_20-22-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PCSK1 HELT SRRM4 KCNJ6 RIMBP2

5.23e-05179100506f92c884189197c86793191c05f65e34925c097
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAM15 VWA1 SHANK3 EDN1 KANK3

5.51e-0518110052c660fcf0404c155955b67ab2958d6e6b0e30024
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAGI1 ADAM15 VWA1 EDN1 KANK3

5.66e-051821005840427d1c23d60482c943ff006b14007ed44d247
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

TRHDE DHDDS FRMD4A PPARGC1B GPT2

5.80e-0518310053f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAGI1 FRMD4B SHANK3 KANK3 FRG2C

5.80e-0518310054d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell5'-GW_trimst-2-LymphNode-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 VWA1 SHANK3 KANK3 MAP3K11

5.96e-051841005df2d42e1eae29fa0a1ed9e389c95b38952b46892
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 VWA1 SHANK3 KANK3 MAP3K11

5.96e-0518410051ace70f12b417185bdd46042833f72b3b6815966
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL36 ZNF318 SBK1 CIITA NOTCH2

6.11e-051851005eb338fcda0b237c2e0b9b4b0daf51febbfe1d79c
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL36 ZNF318 SBK1 CIITA NOTCH2

6.11e-051851005c31bb53852caf36964b83b28bcaee07b679da779
ToppCellfacs-Spleen-nan-3m-Lymphocytic-CD79a_B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF318 SBK1 MGP CIITA NOTCH2

6.43e-051871005b51af2824e65734f333b1325117f4a2e88b17c23
ToppCell367C-Endothelial_cells-Endothelial-D|367C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 VWA1 EDN1 MGP KANK3

6.43e-0518710051342bc614bc4045263c2eb0a535a1dd6c64e7abe
ToppCell367C-Endothelial_cells-Endothelial-D-|367C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 VWA1 EDN1 MGP KANK3

6.43e-0518710057aa206262b14b9f2aaa99e59da38b96c3594d2c9
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PCSK1 SRRM4 CHST13 KCNJ6 RIMBP2

6.43e-05187100598477ba04a42a8da80a72f41a182429f46283595
ToppCellfacs-Spleen-nan-3m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF318 SBK1 MGP CIITA NOTCH2

6.43e-0518710053ca3954f45f167e98a230f2847f0582d74fcd32e
ToppCellfacs-BAT-Fat-3m-Lymphocytic-B_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL36 ZNF318 CREM CIITA NOTCH2

6.43e-05187100563cc89ce24d3f8fb13479a501a20bfbd798d151a
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 IL1RL1

6.43e-05187100503de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCSK1 SRRM4 KCNJ6 CYP26C1 RIMBP2

6.59e-0518810051f912ea015f50570e848259d948a0ba682d64bb4
ToppCell390C-Endothelial_cells-Endothelial-D-|390C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 VWA1 SHANK3 EDN1 MGP

6.59e-05188100550481192da0e9484accb7fcbf9e28a246bb3b80f
ToppCell390C-Endothelial_cells-Endothelial-D|390C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 VWA1 SHANK3 EDN1 MGP

6.59e-05188100530bbd00297de7a2e3e6008aaf37ec0d0617315eb
ToppCellControl-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

MAGI1 SHANK3 EDN1 MGP IL1RL1

6.76e-051891005f83f7521e377ded1522639e9a35c98b3e2725bac
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

MAGI1 SYNPO2 DAPK2 RBM20 PPARGC1B

6.76e-0518910055e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellEndothelial-A-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

SHANK3 EDN1 MGP KANK3 IL1RL1

6.93e-0519010056e83fa0eb8cabe0ffb35375f16e6bf3755ec4977
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HELT SRRM4 DAPK2 EDN1 TENT5B

6.93e-0519010058ceb327dc995f4b83b05d5d6630e1294f0cb49bd
ToppCellwk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PCSK1 SRRM4 CHST13 KCNJ6 RIMBP2

6.93e-0519010055f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCellPCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

6.93e-0519010059a2244c3973aee7270646bf00db7727edb9decc5
ToppCellCOVID-19-Heart-EC_3|Heart / Disease (COVID-19 only), tissue and cell type

ADAM15 FRMD4B SHANK3 CIITA KANK3

6.93e-05190100578e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCellwk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PCSK1 HELT SRRM4 KCNJ6 RIMBP2

6.93e-051901005b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCellPCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

7.11e-051911005edfd5eeff69b5de19c5df3d899e42acd7e015913
ToppCellControl-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

MAGI1 SHANK3 EDN1 KANK3 IL1RL1

7.11e-051911005c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCellControl-Endothelial-VE_Capillary_B|Control / Disease state, Lineage and Cell class

MAGI1 SHANK3 EDN1 KANK3 IL1RL1

7.11e-051911005322237793a1278bafb14e63cab688b353e352dcc
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 MGP KANK3

7.11e-05191100554029b68fb78163c969890886ab0f8fb0dcf3c20
ToppCell11.5-Airway-Epithelial-Neuroendocrine|Airway / Age, Tissue, Lineage and Cell class

PCSK1 HELT SRRM4 KCNJ6 RIMBP2

7.11e-051911005c1bb3ae5c297f55cdadf5b6e53d5296389d5099e
ToppCell5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LPCAT4 SHANK3 EDN1 KANK3 IL1RL1

7.28e-051921005eafead22bba48ac5ee568faa8946c444445c1034
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_capillary_(2)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

7.65e-0519410053c31ac44e8cf4eca3ba7b8bfc05ad3e96a970956
ToppCell356C-Endothelial_cells-Endothelial-A_(Artery)|356C / Donor, Lineage, Cell class and subclass (all cells)

VWA1 SHANK3 EDN1 MGP KANK3

7.65e-0519410052e5b195e02dcd5e9432b9a98b22e0478e65b9ba2
ToppCell356C-Endothelial_cells-Endothelial-A_(Artery)-|356C / Donor, Lineage, Cell class and subclass (all cells)

VWA1 SHANK3 EDN1 MGP KANK3

7.65e-051941005b6b5b0ab506b05a005ba8a05a3c7f4c725ba9200
ToppCellIPF-Endothelial|IPF / Disease state, Lineage and Cell class

MAGI1 SHANK3 EDN1 MGP KANK3

7.65e-0519410059591993aa2dcba3d09a0f1ea8b8f2439c26482d6
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 MGP KANK3

7.83e-051951005cc3d6f98d310e8840ff497d7258c5ccf54e6c624
ToppCellIPF-Endothelial-VE_Peribronchial|IPF / Disease state, Lineage and Cell class

MAGI1 VWA1 SHANK3 MGP KANK3

7.83e-0519510052c3ad3cb79f11119ac69c413a938d21199145040
ToppCell(6)_Endothelial-D|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ADAM15 VWA1 SHANK3 EDN1 MGP

7.83e-051951005c0005a5f2dc63a0cc254c45ac89a2f42df6f8bde
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PCSK1 SRRM4 CHST13 KCNJ6 RIMBP2

7.83e-0519510055f33ece997f074598b4201ff74f592ee07c86a06
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Late_cap|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

7.83e-051951005dfc5da514fb34a2c318a5c4c61f44049fa43960e
ToppCellPCW_13-14-Endothelial|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

8.03e-0519610057286de29a34e13834cd6347c67a1443897fa4ade
ToppCellPCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

8.03e-051961005b826dce5b3daa8eb3d4a530b9564de58d9ce3767
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1D SRRM4 CSMD3 FRMD4A RIMBP2

8.03e-051961005676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellfacs-Lung-ENDOMUCIN-18m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM15 EDN1 KCTD10 KANK3 MAP3K11

8.03e-051961005f6df26ab9eebae893768a4f70a064ce9f60da93c
ToppCellPCW_10-12-Endothelial-Endothelial_immature|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

8.03e-051961005c65b8c7ea34a21897c390e6fb42ee8ca41e9c976
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 VWA1 SHANK3 MGP KANK3

8.03e-051961005a0ba408b802fa6d6e42e6d234b6879fdb1583f81
ToppCellfacs-Lung-ENDOMUCIN|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM15 EDN1 KCTD10 KANK3 MAP3K11

8.03e-05196100569f03546c42c942ab8ac8746167c8d44d574b4c6
ToppCellPCW_13-14-Endothelial-Endothelial_immature|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

8.03e-0519610059ed96085f0acce07bf2f8d4cc212cc50e613be0c
ToppCellPCW_10-12-Endothelial|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

8.03e-0519610052c60dcf9132ee156f25b349e2ac5313709def4f6
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAGI1 ADAM15 CREM SHANK3 EDN1

8.03e-051961005629236f95c838a473b5964a49b7c1b7ad863ea12
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-sinusoidal_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MAGI1 CREM SHANK3 EDN1 KANK3

8.22e-051971005f1080d93acf1a4756d2f2c8cabd1fb50bc7bcd09
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

8.22e-051971005a7922f65a8af4a773e4ce80114e4d895a594fa2f
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 VWA1 SHANK3 EDN1 KANK3

8.22e-0519710057caa2c86dc4d50b57a7db8f7278d1588282ad6db
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 VWA1 SHANK3 EDN1 KANK3

8.22e-051971005951f18f326967206adbbfc422cce9eea3d2e0854
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

8.22e-05197100588859b7b24b36afab4a684fd7abf0e0f8e5b525c
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

8.22e-0519710059b3d6fe76dd7d61a286a28d9466b5f2fece048e1
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 VWA1 SHANK3 MGP KANK3

8.22e-051971005947042f888335c0829d4d5daeb623973eadb3348
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-Late_cap|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

8.22e-051971005797ea1c9f75f88b51fdfc17a2b27ed0199ae64c9
ToppCellPCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating3_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

8.22e-051971005aedc1e3ed6b558bf2f7649919f43049f8348ab85
ToppCellPCW_10-12-Endothelial-Endothelial_cycling|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

8.42e-051981005eac26ed95b4a4343a5dfe1fbecef9374e5947884
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM15 SHANK3 EDN1 MGP KANK3

8.42e-0519810055e781583908c4ee107d986904a646a7c6b8e3591
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1D HIVEP2 SRRM4 CSMD3 FRMD4A

8.42e-051981005c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAM15 VWA1 SHANK3 EDN1 MGP

8.42e-0519810055784e0f9988c917026a692a61b09c7e77e540d13
ToppCell390C-Endothelial_cells-Endothelial-A_(Artery)-|390C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 VWA1 EDN1 MGP KANK3

8.42e-051981005f83956c4b13b5d0a0c6e3d9f580dbf99649ef175
ToppCelltumor_Lung-Endothelial_cells-Tumor_ECs|tumor_Lung / Location, Cell class and cell subclass

MAGI1 VWA1 SHANK3 MGP KANK3

8.42e-0519810055228c4bf2513186140c2c4eaa67a268c732bdc84
ToppCellPCW_13-14-Endothelial-Endothelial_cycling|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

8.42e-0519810058fb624407abb9cb711d8d8a8665014cf6e39559a
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM15 VWA1 SHANK3 MGP KANK3

8.42e-051981005e9e98c20ff7b3f3851db86381550ce7085e2db9e
ToppCellwk_15-18-Endothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

8.42e-051981005dcf453e22dba90c0ae349fa6c3d4c20758bb95af
ToppCell(6)_Endothelial-A_(Artery)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ADAM15 VWA1 SHANK3 EDN1 KANK3

8.42e-05198100544f8cd5afa3685dcc8bfea0b15af5e8817e12e2e
ToppCell368C-Endothelial_cells|368C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 VWA1 SHANK3 EDN1 KANK3

8.42e-0519810059a2c2201baee51581733e183065298a97eba4553
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-intermediate_cap|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 KANK3 MAP3K11

8.42e-05198100575270600b5b29187dfa86f01f8f927ae0621cda4
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1D SRRM4 CSMD3 FRMD4A RIMBP2

8.42e-0519810050ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellBronchus_Control_(B.)-Endothelial-TX-Bronchial_vessel|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

PCSK1 SRRM4 EDN1 KCNJ6 RIMBP2

8.42e-051981005dcf334d13e5b0018fee24febccfef91c9e17843b
ToppCell390C-Endothelial_cells-Endothelial-A_(Artery)|390C / Donor, Lineage, Cell class and subclass (all cells)

ADAM15 VWA1 EDN1 MGP KANK3

8.42e-0519810055b5ccce5de82ea041465e656147cec3b8beb865b
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADAM15 SHANK3 EDN1 MGP KANK3

8.62e-05199100570e05d7c0c68c28754ce0e72434b205aed6287ae
ToppCellParenchyma_COVID-19-Endothelial-TX-Endothelial-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

SHANK3 EDN1 MGP KANK3 IL1RL1

8.62e-051991005edb68a4f622a494f22fd7b25bc40ae0d58456cdb
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SHANK3 EDN1 MGP KANK3 IL1RL1

8.62e-051991005d66514bdffdd96468b543ec96041e42c12472e66
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM15 VWA1 MAP3K6 SHANK3 KANK3

8.62e-051991005da5a88749d859d535daa030d0974485906cc0ba7
DiseaseAuriculo-Ventricular Dissociation

CACNA1D SCN10A

6.39e-054972C0004331
DiseaseHeart Block

CACNA1D SCN10A

6.39e-054972C0018794
Diseaseschizophrenia (implicated_via_orthology)

CACNA1D HIVEP2 CSMD3 SHANK3

7.61e-0568974DOID:5419 (implicated_via_orthology)
Diseasecognitive function measurement

MAGI1 CACNA1D SYNPO2 CCDC185 SZT2 CDKL3 IP6K1 CSMD3 SHANK3 FRMD4A CYP26C1 RIMBP2 DDX53

8.32e-0414349713EFO_0008354
Diseaseulcerative colitis

DAPK2 DHDDS GRID2IP CIITA OS9 KIR3DL2

8.51e-04335976EFO_0000729
Diseaseforehead morphology measurement

ADAM15 SMG6

1.09e-0315972EFO_0007844
DiseaseGastro-enteropancreatic neuroendocrine tumor

CIITA NOTCH2

1.09e-0315972C2930967
DiseaseSinus Node Dysfunction (disorder)

CACNA1D SCN10A

1.09e-0315972C0428908
Diseaseeosinophil count

HIVEP2 CDKL3 DHDDS ZFPM1 WNK1 CREM VANGL2 CIITA CYP26C1 MAP3K11 IL1RL1 PRKDC NOTCH2

1.17e-0314889713EFO_0004842
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

TRHDE CACNA1D FLII TDRKH ADAM15 SGSM2 KCNJ6 PRKDC SMG6

1.30e-03801979EFO_0003888, EFO_0007052, MONDO_0002491
Diseaseresting heart rate

CACNA1D IP6K1 FRMD4B SCN10A

1.50e-03149974EFO_0004351
DiseaseHypertrophy

CREM EDN1

1.58e-0318972C0020564
DiseaseParoxysmal atrial fibrillation

FRMD4B RBM20 EDN1 SCN10A

1.78e-03156974C0235480
Diseasefamilial atrial fibrillation

FRMD4B RBM20 EDN1 SCN10A

1.78e-03156974C3468561
DiseasePersistent atrial fibrillation

FRMD4B RBM20 EDN1 SCN10A

1.78e-03156974C2585653
Diseaseosteoarthritis, knee

MAGI1 POLR2M FRMD4A SMG6

1.86e-03158974EFO_0004616
DiseaseAtrial Fibrillation

FRMD4B RBM20 EDN1 SCN10A

1.95e-03160974C0004238
DiseaseAcute Lung Injury

EDN1 IL1RL1

2.37e-0322972C0242488
Diseasemalaria (is_implicated_in)

KIR3DL1 KIR3DS1

2.82e-0324972DOID:12365 (is_implicated_in)
DiseaseQRS duration

ZFPM1 RBM20 PPARGC1B SCN10A NOTCH2

3.07e-03298975EFO_0005055

Protein segments in the cluster

PeptideGeneStartEntry
AEHERRVRKRRARLV

VANGL2

346

Q9ULK5
RPRTTERHIAVHKRL

TRHDE

26

Q9UKU6
ASAVLKVRPERSRRE

GPT2

31

Q8TD30
SDVARRPLERSRKHR

CCDC185

86

Q8N715
GPRRSSERKRHLERN

SMG6

316

Q86US8
RERIERVRRIHIKRP

KCTD10

291

Q9H3F6
KERHRRQGREVRPDT

BUD23

256

O43709
REKRERRRTIHTFPC

CDR2L

146

Q86X02
RRRPRHAEQIERTKE

CSMD3

426

Q7Z407
HIRRRRDVVTETKTV

ADAM15

201

Q13444
LLAAKEHRRPRETRV

CIITA

401

P33076
HPSVRLTERAKKRRT

CDKL3

451

Q8IVW4
IEEERHSRKRPRSRS

BRPF3

966

Q9ULD4
IRKRELRRERFTHEV

ANKEF1

736

Q9NU02
DRPVRASERKASRLH

CEP72

136

Q9P209
ERETRREKILEARHR

DNAI2

501

Q9GZS0
KDRRRPAVIREPHER

BMS1

1191

Q14692
VRVDEKHRRTYARRP

HMGCS1

456

Q01581
RHLDRSPESDRPRKR

RBM15

651

Q96T37
RSRRKDEARLRESRH

RBM20

781

Q5T481
AHERRLRAVPKVNRT

KIR3DL2

261

P43630
TLRRDASNHKRREPV

NOTCH2

1716

Q04721
MRSKEHERPRRLRLV

FLII

1231

Q13045
TPVSHKVIEKRRRDR

HELT

11

A6NFD8
KHEKRRDVSPERRRE

MAGI1

1371

Q96QZ7
EESHRVVLRPRGKER

LYSMD4

41

Q5XG99
SRHDPASRRRVVEEV

LPCAT4

171

Q643R3
PRHISRDRTKRKIQR

KCNJ6

41

P48051
KRRAVLPRSHRVAGR

FAM86JP

11

Q05BU3
AHERRLPAVRKVNRT

KIR3DL1

261

P43629
RDRHTRVRIAIKEIP

MAP3K6

666

O95382
RIHVTVRRDRAPPER

NXF1

91

Q9UBU9
PTDRRKAATLRERRR

MYF6

91

P23409
STEDHRPLRPRERER

PPM1N

196

Q8N819
RTRERERERDHSPTP

FIP1L1

481

Q6UN15
APVRTRRRRKLYELH

ZFPM1

736

Q8IX07
RVHSLEASRVPKRTR

MDM1

106

Q8TC05
RTPRKRVETSEHFRI

TMPO

256

P42167
RSPVRVKERKITDHR

PPIG

396

Q13427
RMRLEHGIKRRDRSP

CEP135

426

Q66GS9
AERRPRRVEAERPHS

FAM189A2

426

Q15884
RSKRHRSRALEVQTP

FRG2C

156

A6NGY1
SVEVHDPRRASVTRR

FRMD4A

271

Q9P2Q2
VEVHDPRRISVSRRT

FRMD4B

311

Q9Y2L6
KETPARLARLREEHR

DTX3

31

Q8N9I9
LRRHTVRLSRKNPID

IL1RL1

311

Q01638
AGRKRPDAVHRERRR

GRID2IP

121

A4D2P6
IAETPEGRRTSRRKR

KDM1A

101

O60341
TEEDIARRKALHPRR

DAPK2

351

Q9UIK4
REIVRVTLKRDPHRG

FRMPD2

771

Q68DX3
EPHRRRRKVLARVFS

CYP26C1

136

Q6V0L0
DTTEREQPRRKHSRR

IP6K1

106

Q92551
RNPRVEHTLRETSRR

KANK3

126

Q6NY19
RHRETRSRKPGQRRK

DDX53

611

Q86TM3
RIKHVRRVRGREVSP

AHCTF1

1931

Q8WYP5
PISSEERRRRDKQHL

POLR2M

271

P0CAP2
IDSHKRREILSRRPS

CREM

106

Q03060
RTRLHKLSARREERV

DHDDS

296

Q86SQ9
VRGRKIRRSSEEHLR

EDN1

161

P05305
VSKPRHSRRRGRLTK

RPL36

21

Q9Y3U8
ELTSELRRRPSHRAR

SBK1

316

Q52WX2
ERIRERSKPVHELNR

MGP

56

P08493
HDREPQRRSSVKRTR

CACNA1D

1791

Q01668
RERPHVRRRRGTFKR

MAP3K11

466

Q16584
VLDRPEDTRGRRRHK

SZT2

2466

Q5T011
EDTRGRRRHKTESVR

SZT2

2471

Q5T011
PVEKIERSRRSGRRH

RIMBP2

936

O15034
RRAHSPERRREERSV

SFSWAP

811

Q12872
AHERRLPAVRKVNRT

KIR3DS1

261

Q14943
PEAARARRIRRRTDV

SCAND1

161

P57086
RSGFHRLPRRRKRES

RHBDF1

196

Q96CC6
SDRTPSIRHARKRRE

PPARGC1B

881

Q86YN6
VVRQREREAHPATRT

SGSM2

616

O43147
IRLIEDKPRTSHRRS

SRSF6

176

Q13247
DPEHRVRVRVTKLRL

OS9

536

Q13438
LRHRVIATRSPEEIR

TENT5B

261

Q96A09
DPRSTLAKVHRQRRD

CHST13

61

Q8NET6
ERIVISHARPRSLRV

VWA1

336

Q6PCB0
IHRRVEASRTRAPAE

ZNF516

356

Q92618
EVRTRRRRKDDAPPH

ZBTB7B

456

O15156
SVRRQHKTPVRDVRD

ARHGAP40

111

Q5TG30
RIASRDERISVPAKR

SYNPO2

666

Q9UMS6
RKRIAHSAETRVPRK

TDRKH

201

Q9Y2W6
EHRQSRSPSKERDRR

SRRM5

556

B3KS81
RPETREDRTKRLFRH

SHANK3

536

Q9BYB0
KQPVREAERRHRVRL

SLC27A1

346

Q6PCB7
SERRHRIKPRVSEGS

SCN10A

456

Q9Y5Y9
RRRDSPSHLEARRIT

SRRM4

496

A7MD48
PSHLEARRITSARKR

SRRM4

501

A7MD48
PRREHVVTVSKRRNT

IGSF9

1066

Q9P2J2
KEPVSTLHRLSQRRR

PLEKHA3

226

Q9HB20
SLRRPKRIIIRGHDE

PRKDC

3731

P78527
TAVSRKDRVLPHRRQ

FP248

106

Q71RG6
RRERTPEARIHSVKR

ZNF41

26

P51814
VRRPTTADERSLRKI

TOPORS

236

Q9NS56
DAHRARRRLVREPVE

TSPYL6

386

Q8N831
KRHSRSRSPTIKARR

PNISR

556

Q8TF01
VRSRSRHEKTSRPKL

WNK1

1106

Q9H4A3
KATQRRPHGRERRVA

XPC

411

Q01831
KDITARRDLSPRRER

HIVEP2

2121

P31629
KARTRNREVRPAESH

SNX32

326

Q86XE0
GRRIRVDFSITKRPH

TRA2B

186

P62995
LRHTREPRKSREAKE

THEGL

121

P0DJG4
SIRSEERSREAKRPR

ZNF318

261

Q5VUA4
RHVSPREAARVLVRS

TYSND1

371

Q2T9J0
PRRSRRSAFHITKRL

PCSK1

76

P29120