Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	ROCK2 TNK1 BMX MAST4 NTRK2 RPS6KA2 PRKACA PRKACB PGM2L1 ROCK1 PRKCI AKT2 PRKCQ FGFR2 STK32C TEC FGGY ITK EPHA1 PTK7 TXK	6.94e-14	709	74	21	GO:0016773
GeneOntologyMolecularFunction	kinase activity	ROCK2 TNK1 BMX MAST4 NTRK2 RPS6KA2 PRKACA PRKACB PGM2L1 ROCK1 PRKCI AKT2 PRKCQ FGFR2 STK32C TEC FGGY ITK EPHA1 PTK7 TXK	2.95e-13	764	74	21	GO:0016301
GeneOntologyMolecularFunction	protein kinase activity	ROCK2 TNK1 BMX MAST4 NTRK2 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI AKT2 PRKCQ FGFR2 STK32C TEC ITK EPHA1 PTK7 TXK	4.15e-13	600	74	19	GO:0004672
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	ROCK2 TNK1 BMX MAST4 NTRK2 RPS6KA2 PRKACA PRKACB PGM2L1 ROCK1 PRKCI AKT2 PRKCQ FGFR2 STK32C TEC FGGY ITK EPHA1 PTK7 TXK	1.46e-11	938	74	21	GO:0016772
GeneOntologyMolecularFunction	protein tyrosine kinase activity	TNK1 BMX NTRK2 FGFR2 TEC ITK EPHA1 PTK7 TXK	3.24e-09	145	74	9	GO:0004713
GeneOntologyMolecularFunction	non-membrane spanning protein tyrosine kinase activity	TNK1 BMX TEC ITK TXK	7.42e-07	46	74	5	GO:0004715
GeneOntologyMolecularFunction	protein serine kinase activity	ROCK2 MAST4 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI AKT2 PRKCQ STK32C	8.90e-07	363	74	10	GO:0106310
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	ROCK2 MAST4 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI AKT2 PRKCQ STK32C	5.60e-06	446	74	10	GO:0004674
GeneOntologyMolecularFunction	Rho-dependent protein serine/threonine kinase activity	ROCK2 ROCK1	1.35e-05	2	74	2	GO:0072518
GeneOntologyMolecularFunction	polypeptide N-acetylgalactosaminyltransferase activity	GALNTL6 GALNT10 GALNT16	5.32e-05	20	74	3	GO:0004653
GeneOntologyMolecularFunction	transporter activity	SLC7A2 TMEM120B TMEM120A SLC7A3 TRPM5 OSBPL2 SLC16A4 KCNJ6 KCNJ8 KCNN4 BEST3 SLC12A8 LMBRD1 SLC47A2 UNC80	6.40e-05	1289	74	15	GO:0005215
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	NTRK2 FGFR2 EPHA1 PTK7	9.92e-05	65	74	4	GO:0004714
GeneOntologyMolecularFunction	L-ornithine transmembrane transporter activity	SLC7A2 SLC7A3	1.35e-04	5	74	2	GO:0000064
GeneOntologyMolecularFunction	inward rectifier potassium channel activity	KCNJ6 KCNJ8 KCNN4	1.50e-04	28	74	3	GO:0005242
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	NTRK2 FGFR2 EPHA1 PTK7	2.80e-04	85	74	4	GO:0019199
GeneOntologyMolecularFunction	cAMP-dependent protein kinase activity	PRKACA PRKACB	2.81e-04	7	74	2	GO:0004691
GeneOntologyMolecularFunction	monoatomic ion channel activity	TMEM120B TMEM120A TRPM5 KCNJ6 KCNJ8 KCNN4 BEST3 UNC80	2.93e-04	459	74	8	GO:0005216
GeneOntologyMolecularFunction	acetylgalactosaminyltransferase activity	GALNTL6 GALNT10 GALNT16	2.94e-04	35	74	3	GO:0008376
GeneOntologyMolecularFunction	magnesium ion binding	XYLT2 ADPRH MAST4 RPS6KA2 PRKACA PRKACB	3.09e-04	247	74	6	GO:0000287
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC7A2 TMEM120B TMEM120A SLC7A3 TRPM5 SLC16A4 KCNJ6 KCNJ8 KCNN4 BEST3 SLC12A8 SLC47A2 UNC80	3.61e-04	1180	74	13	GO:0022857
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	TRPM5 KCNJ6 KCNJ8 KCNN4 SLC12A8	3.90e-04	167	74	5	GO:0015079
GeneOntologyMolecularFunction	cyclic nucleotide-dependent protein kinase activity	PRKACA PRKACB	4.80e-04	9	74	2	GO:0004690
GeneOntologyMolecularFunction	L-lysine transmembrane transporter activity	SLC7A2 SLC7A3	4.80e-04	9	74	2	GO:0015189
GeneOntologyMolecularFunction	AMP-activated protein kinase activity	PRKACA PRKACB	5.98e-04	10	74	2	GO:0004679
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	TMEM120B TMEM120A TRPM5 KCNJ6 KCNJ8 KCNN4 BEST3 SLC12A8 SLC47A2 UNC80	6.64e-04	793	74	10	GO:0015075
GeneOntologyMolecularFunction	channel activity	TMEM120B TMEM120A TRPM5 KCNJ6 KCNJ8 KCNN4 BEST3 UNC80	7.12e-04	525	74	8	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	TMEM120B TMEM120A TRPM5 KCNJ6 KCNJ8 KCNN4 BEST3 UNC80	7.21e-04	526	74	8	GO:0022803
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	TRPM5 KCNJ6 KCNJ8 KCNN4 BEST3	7.52e-04	193	74	5	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	TRPM5 KCNJ6 KCNJ8 KCNN4 BEST3	8.25e-04	197	74	5	GO:0022834
GeneOntologyMolecularFunction	L-arginine transmembrane transporter activity	SLC7A2 SLC7A3	1.03e-03	13	74	2	GO:0061459
GeneOntologyMolecularFunction	potassium channel activity	TRPM5 KCNJ6 KCNJ8 KCNN4	1.31e-03	128	74	4	GO:0005267
GeneOntologyMolecularFunction	diacylglycerol-dependent serine/threonine kinase activity	PRKCI PRKCQ	1.57e-03	16	74	2	GO:0004697
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	KCNJ6 KCNJ8	1.78e-03	17	74	2	GO:0099508
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	TRPM5 KCNJ6 KCNJ8 KCNN4	1.82e-03	140	74	4	GO:0099094
GeneOntologyMolecularFunction	endopeptidase activator activity	ROCK2 NLRP3	2.22e-03	19	74	2	GO:0061133
GeneOntologyMolecularFunction	basic amino acid transmembrane transporter activity	SLC7A2 SLC7A3	2.47e-03	20	74	2	GO:0015174
GeneOntologyMolecularFunction	UDP-glycosyltransferase activity	GALNTL6 XYLT2 GALNT10 GALNT16	2.52e-03	153	74	4	GO:0008194
GeneOntologyMolecularFunction	tau-protein kinase activity	ROCK2 ROCK1	2.98e-03	22	74	2	GO:0050321
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	SLC7A2 SLC7A3 SLC47A2	3.63e-03	83	74	3	GO:0015101
GeneOntologyMolecularFunction	glycosyltransferase activity	GALNTL6 XYLT2 GALNT10 TMTC1 GALNT16	4.32e-03	288	74	5	GO:0016757
GeneOntologyMolecularFunction	calcium-activated cation channel activity	TRPM5 KCNN4	4.48e-03	27	74	2	GO:0005227
GeneOntologyMolecularFunction	monoatomic ion-gated channel activity	TRPM5 KCNN4	5.88e-03	31	74	2	GO:0022839
GeneOntologyMolecularFunction	voltage-gated potassium channel activity	KCNJ6 KCNJ8 KCNN4	6.45e-03	102	74	3	GO:0005249
GeneOntologyMolecularFunction	small GTPase binding	ROCK2 PRKACA ROCK1 ECT2 RIC1	6.79e-03	321	74	5	GO:0031267
GeneOntologyMolecularFunction	hexosyltransferase activity	GALNTL6 GALNT10 TMTC1 GALNT16	7.84e-03	211	74	4	GO:0016758
GeneOntologyMolecularFunction	gated channel activity	TRPM5 KCNJ6 KCNJ8 KCNN4 BEST3	7.99e-03	334	74	5	GO:0022836
GeneOntologyMolecularFunction	fibronectin binding	TNFAIP6 EPHA1	8.74e-03	38	74	2	GO:0001968
GeneOntologyMolecularFunction	monoatomic cation channel activity	TRPM5 KCNJ6 KCNJ8 KCNN4 UNC80	8.90e-03	343	74	5	GO:0005261
GeneOntologyBiologicalProcess	peptidyl-serine modification	ROCK2 MAST4 NTRK2 RPS6KA2 PRKACA ROCK1 PRKCI AKT2 PRKCQ STK32C GALNT16	2.07e-08	319	75	11	GO:0018209
GeneOntologyBiologicalProcess	peptidyl-serine phosphorylation	ROCK2 MAST4 NTRK2 RPS6KA2 PRKACA ROCK1 PRKCI AKT2 PRKCQ STK32C	1.63e-07	307	75	10	GO:0018105
GeneOntologyBiologicalProcess	peptidyl-amino acid modification	GALNTL6 ROCK2 MAST4 NDUFAF7 NTRK2 RPS6KA2 PRKACA ROCK1 PRKCI AKT2 PRKCQ FGFR2 STK32C GALNT16 EPHA1	1.90e-06	976	75	15	GO:0018193
GeneOntologyBiologicalProcess	positive regulation of protein localization	ROCK2 TM7SF3 PRKACA SREBF2 KCNN4 PRKCI AKT2 PRKCQ TNFAIP6 WLS ECT2	9.05e-06	591	75	11	GO:1903829
GeneOntologyBiologicalProcess	protein autophosphorylation	TNK1 BMX NTRK2 PRKACA FGFR2 EPHA1 TXK	1.93e-05	228	75	7	GO:0046777
GeneOntologyBiologicalProcess	interleukin-4 production	PRKCQ NLRP3 ITK TXK	2.55e-05	47	75	4	GO:0032633
GeneOntologyBiologicalProcess	regulation of angiotensin-activated signaling pathway	ROCK2 ROCK1	7.79e-05	4	75	2	GO:0110061
GeneOntologyBiologicalProcess	regulation of actomyosin structure organization	ROCK2 ROCK1 PRKCQ ECT2 EPHA1	8.27e-05	122	75	5	GO:0110020
GeneOntologyBiologicalProcess	negative regulation of meiotic cell cycle	RPS6KA2 PRKACA PRKACB	8.85e-05	24	75	3	GO:0051447
GeneOntologyBiologicalProcess	peptidyl-threonine modification	GALNTL6 ROCK2 PRKACA ROCK1 GALNT16	9.27e-05	125	75	5	GO:0018210
GeneOntologyBiologicalProcess	positive regulation of establishment of protein localization	TM7SF3 PRKACA SREBF2 KCNN4 AKT2 PRKCQ WLS ECT2	1.07e-04	403	75	8	GO:1904951
GeneOntologyBiologicalProcess	regulation of bicellular tight junction assembly	ROCK2 PRKACA ROCK1	1.42e-04	28	75	3	GO:2000810
GeneOntologyBiologicalProcess	import across plasma membrane	SLC7A2 SLC7A3 KCNJ6 KCNJ8 SLC12A8 AKT2	1.91e-04	230	75	6	GO:0098739
GeneOntologyBiologicalProcess	L-ornithine transmembrane transport	SLC7A2 SLC7A3	1.94e-04	6	75	2	GO:1903352
GeneOntologyBiologicalProcess	bicellular tight junction assembly	ROCK2 PRKACA ROCK1 ECT2	2.17e-04	81	75	4	GO:0070830
GeneOntologyBiologicalProcess	actomyosin structure organization	ROCK2 FLII ROCK1 PRKCQ ECT2 EPHA1	2.35e-04	239	75	6	GO:0031032
GeneOntologyBiologicalProcess	negative regulation of bicellular tight junction assembly	ROCK2 ROCK1	2.71e-04	7	75	2	GO:1903347
GeneOntologyBiologicalProcess	ornithine transport	SLC7A2 SLC7A3	2.71e-04	7	75	2	GO:0015822
GeneOntologyBiologicalProcess	tight junction assembly	ROCK2 PRKACA ROCK1 ECT2	2.98e-04	88	75	4	GO:0120192
GeneOntologyBiologicalProcess	apical junction assembly	ROCK2 PRKACA ROCK1 ECT2	3.25e-04	90	75	4	GO:0043297
GeneOntologyBiologicalProcess	L-arginine import across plasma membrane	SLC7A2 SLC7A3	3.60e-04	8	75	2	GO:0097638
GeneOntologyBiologicalProcess	response to DNA damage checkpoint signaling	ZMPSTE24 SLX4	3.60e-04	8	75	2	GO:0072423
GeneOntologyBiologicalProcess	immune response-regulating signaling pathway	BMX KCNJ8 KCNN4 PRKCQ TEC KIR2DS3 NLRP3 ITK TXK	3.82e-04	615	75	9	GO:0002764
GeneOntologyBiologicalProcess	tight junction organization	ROCK2 PRKACA ROCK1 ECT2	3.84e-04	94	75	4	GO:0120193
GeneOntologyBiologicalProcess	epithelial tube formation	ROCK2 PRKACA PRKACB FGFR2 PTK7	4.21e-04	173	75	5	GO:0072175
GeneOntologyBiologicalProcess	positive regulation of hydrolase activity	ROCK2 ROCK1 AKT2 FGFR2 ECT2 NLRP3 RIC1 EPHA1	4.52e-04	499	75	8	GO:0051345
GeneOntologyBiologicalProcess	establishment of cell polarity	ROCK2 KCNJ8 ROCK1 PRKCI PTK7	4.67e-04	177	75	5	GO:0030010
GeneOntologyBiologicalProcess	regulation of protein localization	ROCK2 KCNJ6 TM7SF3 PRKACA SREBF2 KCNN4 PRKCI AKT2 PRKCQ TNFAIP6 WLS ECT2	5.21e-04	1087	75	12	GO:0032880
GeneOntologyBiologicalProcess	L-lysine transmembrane transport	SLC7A2 SLC7A3	5.76e-04	10	75	2	GO:1903401
GeneOntologyBiologicalProcess	L-lysine transport	SLC7A2 SLC7A3	5.76e-04	10	75	2	GO:1902022
GeneOntologyBiologicalProcess	protein O-linked glycosylation via threonine	GALNTL6 GALNT16	5.76e-04	10	75	2	GO:0018243
GeneOntologyBiologicalProcess	response to cell cycle checkpoint signaling	ZMPSTE24 SLX4	5.76e-04	10	75	2	GO:0072396
GeneOntologyBiologicalProcess	lung-associated mesenchyme development	FGFR2 PTK7	5.76e-04	10	75	2	GO:0060484
GeneOntologyBiologicalProcess	response to DNA integrity checkpoint signaling	ZMPSTE24 SLX4	5.76e-04	10	75	2	GO:0072402
GeneOntologyBiologicalProcess	protein O-linked glycosylation	GALNTL6 GALNT10 TMTC1 GALNT16	5.84e-04	105	75	4	GO:0006493
GeneOntologyBiologicalProcess	cortical actin cytoskeleton organization	ROCK2 ROCK1 ECT2	5.87e-04	45	75	3	GO:0030866
GeneOntologyBiologicalProcess	tube formation	ROCK2 PRKACA PRKACB FGFR2 PTK7	6.00e-04	187	75	5	GO:0035148
GeneOntologyBiologicalProcess	regulation of stress fiber assembly	ROCK2 ROCK1 PRKCQ EPHA1	6.27e-04	107	75	4	GO:0051492
GeneOntologyBiologicalProcess	morphogenesis of embryonic epithelium	ROCK2 PRKACA PRKACB FGFR2 PTK7	6.44e-04	190	75	5	GO:0016331
GeneOntologyBiologicalProcess	CAMKK-AMPK signaling cascade	ZMPSTE24 KCNJ8	7.02e-04	11	75	2	GO:0061762
GeneOntologyBiologicalProcess	positive regulation of protein secretion	TM7SF3 PRKACA KCNN4 PRKCQ WLS	7.08e-04	194	75	5	GO:0050714
GeneOntologyBiologicalProcess	regulation of establishment of protein localization	KCNJ6 TM7SF3 PRKACA SREBF2 KCNN4 AKT2 PRKCQ WLS ECT2	7.38e-04	674	75	9	GO:0070201
GeneOntologyBiologicalProcess	neural tube closure	ROCK2 PRKACA PRKACB PTK7	7.69e-04	113	75	4	GO:0001843
GeneOntologyBiologicalProcess	tube closure	ROCK2 PRKACA PRKACB PTK7	7.95e-04	114	75	4	GO:0060606
GeneOntologyBiologicalProcess	regulation of amyloid-beta formation	ROCK2 NTRK2 ROCK1	8.00e-04	50	75	3	GO:1902003
GeneOntologyBiologicalProcess	potassium ion import across plasma membrane	KCNJ6 KCNJ8 SLC12A8	8.48e-04	51	75	3	GO:1990573
GeneOntologyBiologicalProcess	biomineral tissue development	ROCK2 ZMPSTE24 ROCK1 FGFR2 WLS	8.68e-04	203	75	5	GO:0031214
GeneOntologyBiologicalProcess	export from cell	OSBPL2 KCNJ6 NTRK2 KCNJ8 SURF4 TM7SF3 PRKACA KCNN4 PRKCQ WLS SLC47A2 RIC1	8.76e-04	1153	75	12	GO:0140352
GeneOntologyBiologicalProcess	primary neural tube formation	ROCK2 PRKACA PRKACB PTK7	9.63e-04	120	75	4	GO:0014020
GeneOntologyBiologicalProcess	positive regulation of connective tissue replacement	ROCK2 ROCK1	9.92e-04	13	75	2	GO:1905205
GeneOntologyBiologicalProcess	high-density lipoprotein particle assembly	PRKACA PRKACB	9.92e-04	13	75	2	GO:0034380
GeneOntologyBiologicalProcess	regulation of actin filament bundle assembly	ROCK2 ROCK1 PRKCQ EPHA1	1.06e-03	123	75	4	GO:0032231
GeneOntologyBiologicalProcess	positive regulation of neuron differentiation	GDF5 TLE6 ECT2 DNMT3B	1.06e-03	123	75	4	GO:0045666
GeneOntologyBiologicalProcess	positive regulation of protein transport	TM7SF3 PRKACA KCNN4 PRKCQ WLS ECT2	1.07e-03	319	75	6	GO:0051222
GeneOntologyBiologicalProcess	embryonic morphogenesis	ROCK2 GDF5 PRKACA PRKACB ROCK1 FGFR2 WLS LMBRD1 PTK7	1.10e-03	713	75	9	GO:0048598
GeneOntologyBiologicalProcess	NK T cell differentiation	ITK TXK	1.15e-03	14	75	2	GO:0001865
GeneOntologyBiologicalProcess	cortical cytoskeleton organization	ROCK2 ROCK1 ECT2	1.17e-03	57	75	3	GO:0030865
GeneOntologyBiologicalProcess	stress fiber assembly	ROCK2 ROCK1 PRKCQ EPHA1	1.19e-03	127	75	4	GO:0043149
GeneOntologyBiologicalProcess	contractile actin filament bundle assembly	ROCK2 ROCK1 PRKCQ EPHA1	1.19e-03	127	75	4	GO:0030038
GeneOntologyCellularComponent	Golgi membrane	GALNTL6 XYLT2 GALNT10 SURF4 SREBF2 ROCK1 PRKCI WLS GALNT16 NLRP3 RIC1 TMEM50B	7.99e-06	721	74	12	GO:0000139
GeneOntologyCellularComponent	monoatomic ion channel complex	TRPM5 KCNJ6 KCNJ8 PRKACA KCNN4 BEST3 UNC80	3.80e-04	378	74	7	GO:0034702
GeneOntologyCellularComponent	cAMP-dependent protein kinase complex	PRKACA PRKACB	5.46e-04	10	74	2	GO:0005952
GeneOntologyCellularComponent	excitatory synapse	KCNJ6 NTRK2 FGFR2 TMEM240	5.67e-04	107	74	4	GO:0060076
GeneOntologyCellularComponent	neuromuscular junction	ROCK2 PRKACA PRKCQ SYNGR4	6.73e-04	112	74	4	GO:0031594
HumanPheno	Abnormal distal phalanx morphology of finger	GDF5 ZMPSTE24 KCNJ8 PRKACA PRKACB FGFR2 WLS UNC80	2.01e-06	174	27	8	HP:0009832
HumanPheno	Synostosis of carpal bones	GDF5 PRKACA PRKACB FGFR2	8.65e-06	26	27	4	HP:0005048
HumanPheno	Decreased serum leptin	ZMPSTE24 KCNJ6 AKT2	2.13e-05	11	27	3	HP:0003292
HumanPheno	Delayed eruption of teeth	GDF5 FLII ZMPSTE24 PRKACA PRKACB FGFR2 RIC1	3.56e-05	185	27	7	HP:0000684
HumanPheno	Abnormal circulating leptin concentration	ZMPSTE24 KCNJ6 AKT2	3.67e-05	13	27	3	HP:0004361
HumanPheno	Conical incisor	PRKACA PRKACB FGFR2 RIC1	4.54e-05	39	27	4	HP:0011065
HumanPheno	Carpal synostosis	GDF5 PRKACA PRKACB FGFR2	4.54e-05	39	27	4	HP:0009702
HumanPheno	Abnormal toe phalanx morphology	GDF5 ZMPSTE24 KCNJ8 FGFR2 WLS SLX4	4.69e-05	130	27	6	HP:0010161
HumanPheno	Upper airway obstruction	ZMPSTE24 KCNJ6 FGFR2	1.03e-04	18	27	3	HP:0002781
HumanPheno	Enlarged thorax	XYLT2 ZMPSTE24 PRKACA PRKACB FGFR2	1.13e-04	94	27	5	HP:0100625
HumanPheno	Ankylosis	GDF5 ZMPSTE24 FGFR2	1.22e-04	19	27	3	HP:0031013
HumanPheno	Short limb dwarfism	GDF5 PRKACA PRKACB	1.22e-04	19	27	3	HP:0003505
HumanPheno	Synostosis of carpals/tarsals	GDF5 PRKACA PRKACB FGFR2	1.22e-04	50	27	4	HP:0100266
HumanPheno	Dwarfism	GDF5 PRKACA PRKACB	1.66e-04	21	27	3	HP:0001516
HumanPheno	Conical tooth	PRKACA PRKACB FGFR2 RIC1	1.78e-04	55	27	4	HP:0000698
HumanPheno	Abnormality of dental eruption	GDF5 FLII ZMPSTE24 PRKACA PRKACB FGFR2 RIC1	1.86e-04	240	27	7	HP:0006292
HumanPheno	Abnormal incisor morphology	PRKACA PRKACB FGFR2 RIC1	2.83e-04	62	27	4	HP:0011063
HumanPheno	Abnormal external nose morphology	FLII ZMPSTE24 KCNJ6 KCNJ8 PRKACA PRKACB PGM2L1 FGFR2 WLS SLX4 UNC80 RIC1 DNMT3B	3.13e-04	916	27	13	HP:0010938
HumanPheno	Short distal phalanx of finger	GDF5 ZMPSTE24 KCNJ8 PRKACA PRKACB	3.42e-04	119	27	5	HP:0009882
HumanPheno	Synostosis involving bones of the hand	GDF5 PRKACA PRKACB FGFR2	3.82e-04	67	27	4	HP:0004278
HumanPheno	Prominent nasal tip	KCNJ6 PRKACB PGM2L1	3.98e-04	28	27	3	HP:0005274
HumanPheno	Aplasia/Hypoplasia of the distal phalanges of the hand	GDF5 ZMPSTE24 KCNJ8 PRKACA PRKACB	4.14e-04	124	27	5	HP:0009835
Domain	Prot_kinase_dom	ROCK2 TNK1 BMX MAST4 NTRK2 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI AKT2 PRKCQ FGFR2 STK32C TEC ITK EPHA1 PTK7 TXK	4.58e-14	489	75	19	IPR000719
Domain	PROTEIN_KINASE_DOM	ROCK2 TNK1 BMX MAST4 NTRK2 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI AKT2 PRKCQ FGFR2 STK32C TEC ITK EPHA1 PTK7 TXK	5.30e-14	493	75	19	PS50011
Domain	Protein_kinase_ATP_BS	ROCK2 TNK1 BMX NTRK2 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI AKT2 PRKCQ FGFR2 STK32C TEC ITK EPHA1 TXK	1.19e-13	379	75	17	IPR017441
Domain	PROTEIN_KINASE_ATP	ROCK2 TNK1 BMX MAST4 NTRK2 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI AKT2 PRKCQ FGFR2 STK32C TEC ITK EPHA1 TXK	2.02e-13	459	75	18	PS00107
Domain	Kinase-like_dom	ROCK2 TNK1 BMX MAST4 NTRK2 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI AKT2 PRKCQ FGFR2 STK32C TEC ITK EPHA1 PTK7 TXK	2.87e-13	542	75	19	IPR011009
Domain	AGC-kinase_C	ROCK2 MAST4 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI AKT2 PRKCQ	1.08e-12	56	75	9	IPR000961
Domain	AGC_KINASE_CTER	ROCK2 MAST4 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI AKT2 PRKCQ	1.08e-12	56	75	9	PS51285
Domain	S_TK_X	ROCK2 MAST4 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI AKT2 PRKCQ	1.08e-12	56	75	9	SM00133
Domain	TyrKc	TNK1 BMX NTRK2 FGFR2 TEC ITK EPHA1 PTK7 TXK	7.33e-11	88	75	9	SM00219
Domain	Tyr_kinase_cat_dom	TNK1 BMX NTRK2 FGFR2 TEC ITK EPHA1 PTK7 TXK	7.33e-11	88	75	9	IPR020635
Domain	PROTEIN_KINASE_TYR	TNK1 BMX NTRK2 FGFR2 TEC ITK EPHA1 PTK7 TXK	1.78e-10	97	75	9	PS00109
Domain	Tyr_kinase_AS	TNK1 BMX NTRK2 FGFR2 TEC ITK EPHA1 PTK7 TXK	1.78e-10	97	75	9	IPR008266
Domain	Pkinase_C	ROCK2 RPS6KA2 PRKACA ROCK1 PRKCI AKT2 PRKCQ	3.05e-10	42	75	7	PF00433
Domain	Pkinase_Tyr	TNK1 BMX NTRK2 FGFR2 TEC ITK EPHA1 PTK7 TXK	2.31e-09	129	75	9	PF07714
Domain	Ser-Thr/Tyr_kinase_cat_dom	TNK1 BMX NTRK2 FGFR2 TEC ITK EPHA1 PTK7 TXK	4.19e-09	138	75	9	IPR001245
Domain	Pkinase_C	ROCK2 RPS6KA2 ROCK1 PRKCI AKT2 PRKCQ	7.20e-09	37	75	6	IPR017892
Domain	Ser/Thr_kinase_AS	ROCK2 MAST4 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI AKT2 PRKCQ STK32C	1.58e-06	357	75	10	IPR008271
Domain	S_TKc	ROCK2 MAST4 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI AKT2 PRKCQ STK32C	1.66e-06	359	75	10	SM00220
Domain	PROTEIN_KINASE_ST	ROCK2 MAST4 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI AKT2 PRKCQ STK32C	1.79e-06	362	75	10	PS00108
Domain	Pkinase	ROCK2 MAST4 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI AKT2 PRKCQ STK32C	2.83e-06	381	75	10	PF00069
Domain	BTK	BMX TEC ITK	5.13e-06	9	75	3	SM00107
Domain	Znf_Btk_motif	BMX TEC ITK	5.13e-06	9	75	3	IPR001562
Domain	BTK	BMX TEC ITK	5.13e-06	9	75	3	PF00779
Domain	ZF_BTK	BMX TEC ITK	5.13e-06	9	75	3	PS51113
Domain	ROCK1/ROCK2	ROCK2 ROCK1	1.59e-05	2	75	2	IPR020684
Domain	TMPIT	TMEM120B TMEM120A	1.59e-05	2	75	2	IPR012926
Domain	Rho_Binding	ROCK2 ROCK1	1.59e-05	2	75	2	PF08912
Domain	Rho-bd_dom	ROCK2 ROCK1	1.59e-05	2	75	2	IPR015008
Domain	TMPIT	TMEM120B TMEM120A	1.59e-05	2	75	2	PF07851
Domain	Cat_AA_permease	SLC7A2 SLC7A3	4.76e-05	3	75	2	IPR004755
Domain	AA-permease/SLC12A_dom	SLC7A2 SLC7A3 SLC12A8	9.07e-05	22	75	3	IPR004841
Domain	AA_permease	SLC7A2 SLC7A3 SLC12A8	9.07e-05	22	75	3	PF00324
Domain	PH	ROCK2 BMX ROCK1 AKT2 TEC ECT2 ITK	1.26e-04	278	75	7	SM00233
Domain	ZF_DAG_PE_1	ROCK2 ROCK1 PRKCI PRKCQ	1.27e-04	64	75	4	PS00479
Domain	ZF_DAG_PE_2	ROCK2 ROCK1 PRKCI PRKCQ	1.27e-04	64	75	4	PS50081
Domain	PH_DOMAIN	ROCK2 BMX ROCK1 AKT2 TEC ECT2 ITK	1.28e-04	279	75	7	PS50003
Domain	PH_domain	ROCK2 BMX ROCK1 AKT2 TEC ECT2 ITK	1.31e-04	280	75	7	IPR001849
Domain	Ricin_B_lectin	GALNTL6 GALNT10 GALNT16	1.34e-04	25	75	3	PF00652
Domain	C1	ROCK2 ROCK1 PRKCI PRKCQ	1.35e-04	65	75	4	SM00109
Domain	PE/DAG-bd	ROCK2 ROCK1 PRKCI PRKCQ	1.43e-04	66	75	4	IPR002219
Domain	CAT3	SLC7A2 SLC7A3	1.58e-04	5	75	2	IPR015606
Domain	AA_permease_C	SLC7A2 SLC7A3	1.58e-04	5	75	2	PF13906
Domain	CAT_C	SLC7A2 SLC7A3	1.58e-04	5	75	2	IPR029485
Domain	RICIN	GALNTL6 GALNT10 GALNT16	1.90e-04	28	75	3	SM00458
Domain	RICIN_B_LECTIN	GALNTL6 GALNT10 GALNT16	1.90e-04	28	75	3	PS50231
Domain	Ricin_B_lectin	GALNTL6 GALNT10 GALNT16	2.34e-04	30	75	3	IPR000772
Domain	Glycos_transf_2	GALNTL6 GALNT10 GALNT16	2.34e-04	30	75	3	PF00535
Domain	Glyco_trans_2-like	GALNTL6 GALNT10 GALNT16	2.34e-04	30	75	3	IPR001173
Domain	PH	ROCK2 BMX ROCK1 AKT2 TEC ITK	3.16e-04	229	75	6	PF00169
Domain	HR1	ROCK2 ROCK1	4.39e-04	8	75	2	PF02185
Domain	SH2	BMX TEC ITK TXK	7.29e-04	101	75	4	PF00017
Domain	-	ROCK2 BMX ROCK1 AKT2 TEC ECT2 ITK	9.76e-04	391	75	7	2.30.29.30
Domain	SH2	BMX TEC ITK TXK	1.00e-03	110	75	4	SM00252
Domain	RECEPTOR_TYR_KIN_II	NTRK2 PTK7	1.02e-03	12	75	2	PS00239
Domain	SH2	BMX TEC ITK TXK	1.04e-03	111	75	4	PS50001
Domain	SH2	BMX TEC ITK TXK	1.07e-03	112	75	4	IPR000980
Domain	-	BMX TEC ITK TXK	1.07e-03	112	75	4	3.30.505.10
Domain	AA_permease_2	SLC7A2 SLC7A3	1.21e-03	13	75	2	PF13520
Domain	AA/rel_permease1	SLC7A2 SLC7A3	1.21e-03	13	75	2	IPR002293
Domain	C1_1	ROCK2 PRKCI PRKCQ	1.56e-03	57	75	3	PF00130
Domain	PH_dom-like	ROCK2 BMX ROCK1 AKT2 TEC ECT2 ITK	1.60e-03	426	75	7	IPR011993
Domain	K_chnl_inward-rec_Kir_cyto	KCNJ6 KCNJ8	1.84e-03	16	75	2	IPR013518
Domain	IRK	KCNJ6 KCNJ8	1.84e-03	16	75	2	PF01007
Domain	-	KCNJ6 KCNJ8	1.84e-03	16	75	2	2.60.40.1400
Domain	K_chnl_inward-rec_Kir	KCNJ6 KCNJ8	1.84e-03	16	75	2	IPR016449
Domain	DAG/PE-bd	PRKCI PRKCQ	3.18e-03	21	75	2	IPR020454
Pathway	WP_HIPPO_SIGNALING_REGULATION	NTRK2 PRKACA PRKACB PRKCI PRKCQ FGFR2	3.94e-06	98	61	6	M39830
Pathway	REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS	RPS6KA2 PRKACA PRKACB	3.38e-05	15	61	3	MM15103
Pathway	REACTOME_SIGNALING_BY_VEGF	ROCK2 PRKACA PRKACB ROCK1 AKT2	8.12e-05	103	61	5	MM14752
Pathway	REACTOME_SIGNALING_BY_VEGF	ROCK2 PRKACA PRKACB ROCK1 AKT2	9.31e-05	106	61	5	M27077
Pathway	KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION	ROCK2 PRKACA PRKACB ROCK1 PRKCQ	1.37e-04	115	61	5	M9387
Pathway	WP_CHEMOKINE_SIGNALING_PATHWAY	ROCK2 PRKACA PRKACB ROCK1 AKT2 ITK	1.39e-04	184	61	6	MM15943
Pathway	KEGG_CHEMOKINE_SIGNALING_PATHWAY	ROCK2 PRKACA PRKACB ROCK1 AKT2 ITK	1.57e-04	188	61	6	M4844
Pathway	KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_MAP_TO_LPA_GNA12_13_RHOA_SIGNALING_PATHWAY	ROCK2 ROCK1	1.83e-04	5	61	2	M49031
Pathway	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_KEY_METABOLIC_FACTORS	PRKACA PRKACB	1.83e-04	5	61	2	M26988
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_ROCKS	ROCK2 ROCK1	1.83e-04	5	61	2	MM15221
Pathway	REACTOME_EPHA_MEDIATED_GROWTH_CONE_COLLAPSE	ROCK2 ROCK1 EPHA1	2.60e-04	29	61	3	M27309
Pathway	WP_LIPID_METABOLISM_PATHWAY	PRKACA PRKACB AKT2	2.60e-04	29	61	3	M39762
Pathway	REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION	PRKACA PRKACB	2.73e-04	6	61	2	MM14628
Pathway	KEGG_O_GLYCAN_BIOSYNTHESIS	GALNTL6 GALNT10 GALNT16	2.88e-04	30	61	3	M6929
Pathway	KEGG_MEDICUS_REFERENCE_PKA_HOLOENZYME	PRKACA PRKACB	3.81e-04	7	61	2	M47896
Pathway	REACTOME_HDL_ASSEMBLY	PRKACA PRKACB	3.81e-04	7	61	2	MM15560
Pathway	REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES	ROCK2 NTRK2 RPS6KA2 PRKACA PRKACB ROCK1 AKT2 FGFR2 TEC	4.37e-04	532	61	9	M27870
Pathway	WP_GLIOBLASTOMA_SIGNALING	PRKCI AKT2 PRKCQ FGFR2	4.52e-04	83	61	4	M39637
Pathway	REACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS	RPS6KA2 PRKACA PRKACB	4.57e-04	35	61	3	MM15109
Pathway	KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION	RPS6KA2 PRKACA PRKACB AKT2	4.95e-04	85	61	4	M3578
Pathway	SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES	RPS6KA2 AKT2 TEC	4.97e-04	36	61	3	M1315
Pathway	REACTOME_HDL_ASSEMBLY	PRKACA PRKACB	5.07e-04	8	61	2	M27840
Pathway	WP_EPAC1_AND_PKA_REDUCTION_OF_RETINAL_INFLAMMATION	PRKACB NLRP3	5.07e-04	8	61	2	M48325
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS	BMX ROCK1 PRKCQ	5.39e-04	37	61	3	MM14488
Pathway	REACTOME_NEURONAL_SYSTEM	PTPRD KCNJ6 RPS6KA2 KCNJ8 PRKACA PRKACB KCNN4	5.83e-04	335	61	7	MM14503
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS	BMX ROCK1 PRKCQ	5.84e-04	38	61	3	M495
Pathway	WP_G_PROTEIN_SIGNALING_PATHWAYS	PRKACA PRKACB PRKCI PRKCQ	6.14e-04	90	61	4	MM15882
Pathway	WP_G_PROTEIN_SIGNALING	PRKACA PRKACB PRKCI PRKCQ	6.40e-04	91	61	4	M39426
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_PI3K_SIGNALING_PATHWAY	AKT2 FGFR2	6.50e-04	9	61	2	M47397
Pathway	REACTOME_ROBO_RECEPTORS_BIND_AKAP5	PRKACA PRKACB	6.50e-04	9	61	2	M27877
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNA12_13_RHO_SIGNALING_PATHWAY	ROCK2 ROCK1	6.50e-04	9	61	2	M47546
Pathway	WP_CHEMOKINE_SIGNALING	ROCK2 PRKACB ROCK1 AKT2 ITK	7.25e-04	165	61	5	M39400
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	ROCK2 RPS6KA2 PRKACA PRKACB SREBF2 ROCK1 PRKCQ SCD5 EPHA1	7.65e-04	575	61	9	M29853
Pathway	KEGG_MEDICUS_REFERENCE_AVP_V2R_PKA_SIGNALING_PATHWAY	PRKACA PRKACB	8.11e-04	10	61	2	M47648
Pathway	WP_MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY	ROCK2 ROCK1 AKT2 FGFR2	8.79e-04	99	61	4	MM15905
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	ROCK2 PRKACA PRKACB ROCK1 PRKCQ EPHA1	9.00e-04	261	61	6	MM15676
Pathway	SIG_CHEMOTAXIS	ROCK2 ROCK1 AKT2	9.61e-04	45	61	3	M5193
Pathway	REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE	ROCK2 ROCK1	9.88e-04	11	61	2	MM15046
Pathway	KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAA_TO_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY	ROCK2 ROCK1	9.88e-04	11	61	2	M47721
Pathway	KEGG_MAPK_SIGNALING_PATHWAY	NTRK2 RPS6KA2 PRKACA PRKACB AKT2 FGFR2	1.01e-03	267	61	6	M10792
Pathway	WP_TRANSLATION_INHIBITORS_IN_CHRONICALLY_ACTIVATED_PDGFRA_CELLS	RPS6KA2 PRKACA AKT2	1.03e-03	46	61	3	M39805
Pathway	WP_CHRONIC_HYPERGLYCEMIA_IMPAIRMENT_OF_NEURON_FUNCTION	MMP27 PRKCI PRKCQ	1.03e-03	46	61	3	M46450
Pathway	WP_MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY	ROCK2 ROCK1 AKT2 FGFR2	1.06e-03	104	61	4	M39625
Pathway	WP_MICROTUBULE_CYTOSKELETON_REGULATION	NTRK2 PRKACA ROCK1	1.16e-03	48	61	3	M39566
Pathway	WP_RAS_SIGNALING	NTRK2 PRKACA PRKACB AKT2 FGFR2	1.18e-03	184	61	5	M39764
Pathway	REACTOME_REGULATION_OF_GLYCOLYSIS_BY_FRUCTOSE_2_6_BISPHOSPHATE_METABOLISM	PRKACA PRKACB	1.18e-03	12	61	2	M27950
Pathway	REACTOME_CREB1_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_ADENYLATE_CYCLASE	PRKACA PRKACB	1.18e-03	12	61	2	M27363
Pathway	KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY	AKT2 PRKCQ TEC ITK	1.22e-03	108	61	4	M9904
Pathway	REACTOME_APOPTOTIC_EXECUTION_PHASE	BMX ROCK1 PRKCQ	1.23e-03	49	61	3	MM15448
Pathway	WP_FOCAL_ADHESION	ROCK2 TNK1 ROCK1 AKT2 TXK	1.27e-03	187	61	5	MM15913
Pathway	WP_DOPAMINE_METABOLISM	PRKACA PRKACB	1.39e-03	13	61	2	M39622
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNA12_13_RHO_SIGNALING_PATHWAY	ROCK2 ROCK1	1.39e-03	13	61	2	M47547
Pathway	KEGG_MEDICUS_REFERENCE_LPA_GNA12_13_RHOA_SIGNALING_PATHWAY	ROCK2 ROCK1	1.39e-03	13	61	2	M47731
Pathway	REACTOME_APOPTOTIC_EXECUTION_PHASE	BMX ROCK1 PRKCQ	1.47e-03	52	61	3	M2341
Pathway	KEGG_TASTE_TRANSDUCTION	TRPM5 PRKACA PRKACB	1.47e-03	52	61	3	M5785
Pathway	KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION	ROCK2 ROCK1 ITK TXK	1.58e-03	116	61	4	M2164
Pathway	WP_FOCAL_ADHESION	ROCK2 TNK1 ROCK1 AKT2 TXK	1.67e-03	199	61	5	M39402
Pathway	PID_TXA2PATHWAY	PRKACA ROCK1 PRKCQ	1.82e-03	56	61	3	M99
Pathway	WP_HIPPOMERLIN_SIGNALING_DYSREGULATION	NTRK2 PRKACA PRKACB FGFR2	1.85e-03	121	61	4	M39823
Pathway	REACTOME_RAP1_SIGNALLING	PRKACA PRKACB	1.87e-03	15	61	2	MM15019
Pathway	REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING	ROCK2 ROCK1	1.87e-03	15	61	2	MM15037
Pathway	KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY	PRKACA PRKACB	1.87e-03	15	61	2	M47794
Pathway	PID_THROMBIN_PAR4_PATHWAY	ROCK2 ROCK1	1.87e-03	15	61	2	M138
Pathway	KEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY	PRKACA PRKACB	1.87e-03	15	61	2	M47504
Pathway	REACTOME_NEURONAL_SYSTEM	PTPRD KCNJ6 RPS6KA2 KCNJ8 PRKACA PRKACB KCNN4	1.91e-03	411	61	7	M735
Pathway	REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES	ROCK2 NTRK2 RPS6KA2 PRKACA PRKACB ROCK1 AKT2	2.10e-03	418	61	7	MM15587
Pathway	KEGG_MEDICUS_REFERENCE_DRD1_GNAS_AC_PKA_SIGNALING_PATHWAY	PRKACA PRKACB	2.13e-03	16	61	2	M47551
Pathway	KEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY	PRKACA PRKACB	2.13e-03	16	61	2	M47645
Pathway	REACTOME_DARPP_32_EVENTS	PRKACA PRKACB	2.13e-03	16	61	2	MM14699
Pathway	KEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY	PRKACA PRKACB	2.13e-03	16	61	2	M47650
Pathway	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	PRKACA PRKACB	2.13e-03	16	61	2	MM14492
Pathway	REACTOME_RAP1_SIGNALLING	PRKACA PRKACB	2.13e-03	16	61	2	M923
Pathway	WP_AIRWAY_SMOOTH_MUSCLE_CELL_CONTRACTION	ROCK2 ROCK1	2.13e-03	16	61	2	M40060
Pathway	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	GALNTL6 GALNT10 GALNT16	2.21e-03	60	61	3	MM15636
Pathway	WP_INVOLVEMENT_OF_SECRETASE_IN_NEURODEGENERATIVE_DISEASES	NTRK2 AKT2	2.40e-03	17	61	2	M48086
Pathway	REACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY	PRKACA PRKACB	2.40e-03	17	61	2	MM15561
Pathway	REACTOME_PKA_ACTIVATION_IN_GLUCAGON_SIGNALLING	PRKACA PRKACB	2.40e-03	17	61	2	M26995
Pathway	KEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY	PRKACA PRKACB	2.40e-03	17	61	2	M47544
Pathway	WP_MAP3K1_ROLE_IN_PROMOTING_AND_BLOCKING_GONADAL_DETERMINATION	ROCK1 FGFR2	2.40e-03	17	61	2	M39907
Pathway	REACTOME_CD209_DC_SIGN_SIGNALING	PRKACA PRKACB	2.40e-03	17	61	2	MM15215
Pathway	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	GALNTL6 GALNT10 GALNT16	2.43e-03	62	61	3	M546
Pathway	REACTOME_EPH_EPHRIN_SIGNALING	ROCK2 ROCK1 EPHA1	2.78e-03	65	61	3	MM14911
Pathway	REACTOME_INNATE_IMMUNE_SYSTEM	ADGRE3 RPS6KA2 SURF4 PRKACA PRKACB ROCK1 PRKCQ TNFAIP6 TEC NLRP3 ITK TXK	2.88e-03	1128	61	12	M1036
Pathway	KEGG_INSULIN_SIGNALING_PATHWAY	PRKACA PRKACB PRKCI AKT2	2.90e-03	137	61	4	M18155
Pathway	REACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY	PRKACA PRKACB	3.00e-03	19	61	2	M27841
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_ROCKS	ROCK2 ROCK1	3.00e-03	19	61	2	M27493
Pathway	REACTOME_SIGNALING_BY_GPCR	ROCK2 ADGRE3 RPS6KA2 PRKACA PRKACB ROCK1 AKT2 PRKCQ ECT2	3.04e-03	702	61	9	M746
Pathway	REACTOME_RHOB_GTPASE_CYCLE	ROCK2 ROCK1 ECT2	3.30e-03	69	61	3	MM15596
Pathway	REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE	ROCK2 ROCK1	3.33e-03	20	61	2	M18415
Pathway	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	PRKACA PRKACB	3.33e-03	20	61	2	M759
Pathway	REACTOME_RHOB_GTPASE_CYCLE	ROCK2 ROCK1 ECT2	3.43e-03	70	61	3	M41806
Pathway	KEGG_LONG_TERM_POTENTIATION	RPS6KA2 PRKACA PRKACB	3.43e-03	70	61	3	M3115
Pathway	REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION	KCNJ6 RPS6KA2 PRKACA PRKACB	3.47e-03	144	61	4	MM14501
Pathway	WP_BURN_WOUND_HEALING	FLII NLRP3	3.67e-03	21	61	2	MM15978
Pathway	REACTOME_CD209_DC_SIGN_SIGNALING	PRKACA PRKACB	3.67e-03	21	61	2	M27485
Pathway	KEGG_MEDICUS_REFERENCE_MICROTUBULE_RHOA_SIGNALING_PATHWAY	ROCK2 ROCK1	3.67e-03	21	61	2	M47767
Pathway	WP_PROGERIAASSOCIATED_LIPODYSTROPHY	ZMPSTE24 KCNJ6	4.02e-03	22	61	2	M42534
Pathway	WP_7Q1123_DISTAL_COPY_NUMBER_VARIATION	TMEM120B TMEM120A	4.02e-03	22	61	2	M48101
Pathway	KEGG_WNT_SIGNALING_PATHWAY	ROCK2 PRKACA PRKACB ROCK1	4.11e-03	151	61	4	M19428
Pathway	WP_MAPK_SIGNALING	NTRK2 PRKACA PRKACB AKT2 FGFR2	4.17e-03	246	61	5	M39597
Pubmed	The protein tyrosine kinase family of the human genome.	TNK1 BMX NTRK2 FGFR2 TEC ITK EPHA1 TXK	1.37e-11	83	77	8	11114734
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	TNK1 BMX NTRK2 RPS6KA2 PRKACB PRKCI AKT2 PRKCQ STK32C ITK EPHA1	6.43e-10	372	77	11	22939624
Pubmed	Tec kinases Itk and Rlk are required for CD8+ T cell responses to virus infection independent of their role in CD4+ T cell help.	TEC ITK TXK	1.04e-08	3	77	3	16424186
Pubmed	Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases.	BMX TEC ITK	1.04e-07	5	77	3	12573241
Pubmed	The accessory factor Nef links HIV-1 to Tec/Btk kinases in an Src homology 3 domain-dependent manner.	BMX TEC ITK	1.04e-07	5	77	3	24722985
Pubmed	The human immunodeficiency virus coat protein gp120 promotes forward trafficking and surface clustering of NMDA receptors in membrane microdomains.	PRKACA PRKACB PRKCI PRKCQ	1.29e-07	21	77	4	22114277
Pubmed	Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase C- and cAMP-dependent protein kinase pathways.	PRKACA PRKACB PRKCI PRKCQ	1.29e-07	21	77	4	9671211
Pubmed	The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix.	PRKACA PRKACB PRKCI PRKCQ	1.58e-07	22	77	4	9151826
Pubmed	T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.	TEC ITK TXK	2.08e-07	6	77	3	15662016
Pubmed	Role of phosphorylation in the nuclear biology of HIV-1.	PRKACA PRKACB PRKCI PRKCQ	3.75e-07	27	77	4	21651489
Pubmed	Screening for cell migration inhibitors via automated microscopy reveals a Rho-kinase inhibitor.	ROCK2 PRKACA ROCK1	5.80e-07	8	77	3	15797222
Pubmed	Genetic modifiers of EGFR dependence in non-small cell lung cancer.	NTRK2 FGFR2 ITK	8.68e-07	9	77	3	25512530
Pubmed	Opposite effects of HIV-1 p17 variants on PTEN activation and cell growth in B cells.	ROCK2 ROCK1 AKT2	1.70e-06	11	77	3	21423810
Pubmed	Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.	NTRK2 FGFR2 EPHA1 PTK7	1.91e-06	40	77	4	30898150
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	SLC7A3 ZMPSTE24 KCNJ8 CHAC2 SREBF2 ROCK1 GLB1L2 TEC SCD5 WLS LMBRD1 SLX4	4.50e-06	1084	77	12	11544199
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	DPP9 RPS6KA2 PRKACA PRKACB MMP27 PRKCI AKT2 PRKCQ GALNT16 ITK	4.83e-06	730	77	10	34857952
Pubmed	ROCK 1 and 2 affect the spatial architecture of 3D spheroids derived from human corneal stromal fibroblasts in different manners.	ROCK2 ROCK1	4.84e-06	2	77	2	35523828
Pubmed	Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway.	ROCK2 ROCK1	4.84e-06	2	77	2	29115372
Pubmed	Investigation of the Rho-kinase Gene Polymorphism in Primary Open-angle Glaucoma.	ROCK2 ROCK1	4.84e-06	2	77	2	24617500
Pubmed	[Ouabain induces Rho-dependent rock activation and membrane blebbing incultured endothelial cells].	ROCK2 ROCK1	4.84e-06	2	77	2	25916120
Pubmed	Determinants of intra versus intermolecular self-association within the regulatory domains of Rlk and Itk.	ITK TXK	4.84e-06	2	77	2	12798690
Pubmed	Tec kinases regulate TCR-mediated recruitment of signaling molecules and integrin-dependent cell adhesion.	ITK TXK	4.84e-06	2	77	2	16237085
Pubmed	PKCtheta and PKA are antagonistic partners in the NF-AT transactivation pathway of primary mouse CD3+ T lymphocytes.	PRKACA PRKCQ	4.84e-06	2	77	2	16514061
Pubmed	PKCtheta and Itk functionally interact during primary mouse CD3+ T cell activation.	PRKCQ ITK	4.84e-06	2	77	2	19682494
Pubmed	A role for the Tec family tyrosine kinase Txk in T cell activation and thymocyte selection.	ITK TXK	4.84e-06	2	77	2	10562318
Pubmed	Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase.	PRKACA PRKACB	4.84e-06	2	77	2	3023318
Pubmed	ROCK inhibitor Y-27632 inhibits the growth, migration, and invasion of Tca8113 and CAL-27 cells in tongue squamous cell carcinoma.	ROCK2 ROCK1	4.84e-06	2	77	2	26468018
Pubmed	ROCK1 and ROCK2 regulate epithelial polarisation and geometric cell shape.	ROCK2 ROCK1	4.84e-06	2	77	2	22462535
Pubmed	Distinct Roles For ROCK1 and ROCK2 in the Regulation of Oxldl-Mediated Endothelial Dysfunction.	ROCK2 ROCK1	4.84e-06	2	77	2	30165352
Pubmed	The Role of ROCK in Platelet-Monocyte Collaborative Induction of Thromboinflammation during Acute Coronary Syndrome.	ROCK2 ROCK1	4.84e-06	2	77	2	32877952
Pubmed	Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity.	ITK TXK	4.84e-06	2	77	2	10213685
Pubmed	Toll-like receptor signaling in macrophages is regulated by extracellular substrate stiffness and Rho-associated coiled-coil kinase (ROCK1/2).	ROCK2 ROCK1	4.84e-06	2	77	2	29800294
Pubmed	Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts.	ROCK2 ROCK1	4.84e-06	2	77	2	18668558
Pubmed	ROCK1 and ROCK2 Are Down-regulated in Aggressive and Advanced Skin Melanomas - A Clinicopathological Perspective.	ROCK2 ROCK1	4.84e-06	2	77	2	32234882
Pubmed	Long-term inhibition of Rho-kinase suppresses left ventricular remodeling after myocardial infarction in mice.	ROCK2 ROCK1	4.84e-06	2	77	2	15096457
Pubmed	Oncogenic activity of Ect2 is regulated through protein kinase C iota-mediated phosphorylation.	PRKCI ECT2	4.84e-06	2	77	2	21189248
Pubmed	ROCK1 & 2 perform overlapping and unique roles in angiogenesis and angiosarcoma tumor progression.	ROCK2 ROCK1	4.84e-06	2	77	2	22934846
Pubmed	Functional role of Rho-kinase in ameloblast differentiation.	ROCK2 ROCK1	4.84e-06	2	77	2	21792909
Pubmed	Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity.	ROCK2 ROCK1	4.84e-06	2	77	2	20803696
Pubmed	Role of Rho Kinase and Fasudil on Synaptic Plasticity in Multiple Sclerosis.	ROCK2 ROCK1	4.84e-06	2	77	2	26481340
Pubmed	Inhibition of ROCK activity allows InlF-mediated invasion and increased virulence of Listeria monocytogenes.	ROCK2 ROCK1	4.84e-06	2	77	2	18331468
Pubmed	The Rho Kinase Isoforms ROCK1 and ROCK2 Each Contribute to the Development of Experimental Pulmonary Fibrosis.	ROCK2 ROCK1	4.84e-06	2	77	2	29211497
Pubmed	The connection between the cardiac glycoside-induced senescent cell morphology and Rho/Rho kinase pathway.	ROCK2 ROCK1	4.84e-06	2	77	2	30369081
Pubmed	Tec family kinases modulate thresholds for thymocyte development and selection.	ITK TXK	4.84e-06	2	77	2	11015440
Pubmed	Role of rho-kinase gene polymorphisms and protein expressions in colorectal cancer development.	ROCK2 ROCK1	4.84e-06	2	77	2	23328676
Pubmed	The expression and prognostic value of ROCK I and ROCK II and their role in human breast cancer.	ROCK2 ROCK1	4.84e-06	2	77	2	18695890
Pubmed	Mutation of Tec family kinases alters T helper cell differentiation.	ITK TXK	4.84e-06	2	77	2	11702066
Pubmed	Opposing signaling of ROCK1 and ROCK2 determines the switching of substrate specificity and the mode of migration of glioblastoma cells.	ROCK2 ROCK1	4.84e-06	2	77	2	24170433
Pubmed	Rho-associated kinases play an essential role in cardiac morphogenesis and cardiomyocyte proliferation.	ROCK2 ROCK1	4.84e-06	2	77	2	12508221
Pubmed	Novel interactions between the 5-HT transporter, 5-HT1B receptors and Rho kinase in vivo and in pulmonary fibroblasts.	ROCK2 ROCK1	4.84e-06	2	77	2	18695640
Pubmed	Remnant lipoproteins from patients with sudden cardiac death enhance coronary vasospastic activity through upregulation of Rho-kinase.	ROCK2 ROCK1	4.84e-06	2	77	2	15044207
Pubmed	Differential regulation of adhesion complex turnover by ROCK1 and ROCK2.	ROCK2 ROCK1	4.84e-06	2	77	2	22348083
Pubmed	Rho-associated kinase is a therapeutic target in neuroblastoma.	ROCK2 ROCK1	4.84e-06	2	77	2	28739902
Pubmed	Targeting interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) using a novel covalent inhibitor PRN694.	ITK TXK	4.84e-06	2	77	2	25593320
Pubmed	Investigation of -PRKACA/-PRKACB fusion genes in oncocytic tumors of the pancreatobiliary and other systems.	PRKACA PRKACB	4.84e-06	2	77	2	36152045
Pubmed	PRKACA/PRKACB Fusions in Pancreatobiliary Intraductal Oncocytic Papillary Neoplasms Including Those With Atypical Morphology: An Analysis of 22 Cases Expanding Morphologic Spectrum.	PRKACA PRKACB	4.84e-06	2	77	2	38841868
Pubmed	Common variants of ROCKs and the risk of hypertension, and stroke: Two case-control studies and a follow-up study in Chinese Han population.	ROCK2 ROCK1	4.84e-06	2	77	2	29246448
Pubmed	Fibroblast deletion of ROCK2 attenuates cardiac hypertrophy, fibrosis, and diastolic dysfunction.	ROCK2 ROCK1	4.84e-06	2	77	2	28679962
Pubmed	Diverse signaling pathways regulate fibroblast differentiation and transformation through Rho kinase activation.	ROCK2 ROCK1	4.84e-06	2	77	2	17167780
Pubmed	Association of Rho-kinase Gene Polymorphisms with Respiratory Distress Syndrome in Preterm Neonates.	ROCK2 ROCK1	4.84e-06	2	77	2	27269648
Pubmed	Hyperoxia increases the elastic modulus of alveolar epithelial cells through Rho kinase.	ROCK2 ROCK1	4.84e-06	2	77	2	24289040
Pubmed	Rho kinase in the regulation of cell death and survival.	ROCK2 ROCK1	4.84e-06	2	77	2	17347801
Pubmed	Distinct distribution and localization of Rho-kinase in mouse epithelial, muscle and neural tissues.	ROCK2 ROCK1	4.84e-06	2	77	2	22986902
Pubmed	Molecular and behavioral effects of a null mutation in all PKA C beta isoforms.	PRKACA PRKACB	4.84e-06	2	77	2	12139926
Pubmed	Activation of Rho kinase isoforms in lung endothelial cells during inflammation.	ROCK2 ROCK1	4.84e-06	2	77	2	19201893
Pubmed	Human Txk: genomic organization, structure and contiguous physical linkage with the Tec gene.	TEC TXK	4.84e-06	2	77	2	8632917
Pubmed	Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation.	ROCK2 ROCK1	4.84e-06	2	77	2	19997641
Pubmed	TMEM120A and B: Nuclear Envelope Transmembrane Proteins Important for Adipocyte Differentiation.	TMEM120B TMEM120A	4.84e-06	2	77	2	26024229
Pubmed	Role of Rho kinase isoforms in murine allergic airway responses.	ROCK2 ROCK1	4.84e-06	2	77	2	21565918
Pubmed	Characterization of genomic clones coding for the C alpha and C beta subunits of mouse cAMP-dependent protein kinase.	PRKACA PRKACB	4.84e-06	2	77	2	2833513
Pubmed	Cryo-EM structures of human TMEM120A and TMEM120B.	TMEM120B TMEM120A	4.84e-06	2	77	2	34465718
Pubmed	The Rho kinase pathway regulates mouse adult neural precursor cell migration.	ROCK2 ROCK1	4.84e-06	2	77	2	21732490
Pubmed	Comparative Study of ROCK1 and ROCK2 in Hippocampal Spine Formation and Synaptic Function.	ROCK2 ROCK1	4.84e-06	2	77	2	30826947
Pubmed	Adjustable passive stiffness in mouse bladder: regulated by Rho kinase and elevated following partial bladder outlet obstruction.	ROCK2 ROCK1	4.84e-06	2	77	2	22205227
Pubmed	A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression.	ITK TXK	4.84e-06	2	77	2	26466958
Pubmed	Sulfide induces apoptosis and Rho kinase-dependent cell blebbing in Jurkat cells.	ROCK2 ROCK1	4.84e-06	2	77	2	23479079
Pubmed	Evidence for Rho-kinase activation in patients with pulmonary arterial hypertension.	ROCK2 ROCK1	4.84e-06	2	77	2	19590140
Pubmed	Rho-GTPase effector ROCK phosphorylates cofilin in actin-meditated cytokinesis during mouse oocyte meiosis.	ROCK2 ROCK1	4.84e-06	2	77	2	24429217
Pubmed	Rocks: multifunctional kinases in cell behaviour.	ROCK2 ROCK1	4.84e-06	2	77	2	12778124
Pubmed	Rho kinases regulate corneal epithelial wound healing.	ROCK2 ROCK1	4.84e-06	2	77	2	18495812
Pubmed	ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens.	ROCK2 ROCK1	4.84e-06	2	77	2	28035042
Pubmed	Endothelial dysfunction: the role of sterol regulatory element-binding protein-induced NOD-like receptor family pyrin domain-containing protein 3 inflammasome in atherosclerosis.	SREBF2 NLRP3	4.84e-06	2	77	2	25188917
Pubmed	Distinct and complementary functions of rho kinase isoforms ROCK1 and ROCK2 in prefrontal cortex structural plasticity.	ROCK2 ROCK1	4.84e-06	2	77	2	30196430
Pubmed	Global consequences of activation loop phosphorylation on protein kinase A.	PRKACA PRKACB	4.84e-06	2	77	2	19965870
Pubmed	Role of Rho-kinase in regulation of insulin action and glucose homeostasis.	ROCK2 ROCK1	4.84e-06	2	77	2	16098829
Pubmed	Rho kinase proteins display aberrant upregulation in vascular tumors and contribute to vascular tumor growth.	ROCK2 ROCK1	4.84e-06	2	77	2	28709411
Pubmed	Sterol regulatory element binding protein 2 activation of NLRP3 inflammasome in endothelium mediates hemodynamic-induced atherosclerosis susceptibility.	SREBF2 NLRP3	4.84e-06	2	77	2	23838163
Pubmed	Small molecule inhibition of cytoskeletal dynamics in melanoma tumors results in altered transcriptional expression patterns of key genes involved in tumor initiation and progression.	ROCK2 ROCK1	4.84e-06	2	77	2	21471517
Pubmed	Rho kinase inhibitors block melanoma cell migration and inhibit metastasis.	ROCK2 ROCK1	4.84e-06	2	77	2	25840982
Pubmed	ROCK-I and ROCK-II cooperatively regulate closure of eyelid and ventral body wall in mouse embryo.	ROCK2 ROCK1	4.84e-06	2	77	2	16098146
Pubmed	Protein kinase A translocation and insulin secretion in pancreatic beta-cells: studies with adenylate cyclase toxin from Bordetella pertussis.	PRKACA PRKACB	4.84e-06	2	77	2	12180908
Pubmed	Different roles of myocardial ROCK1 and ROCK2 in cardiac dysfunction and postcapillary pulmonary hypertension in mice.	ROCK2 ROCK1	4.84e-06	2	77	2	29987023
Pubmed	ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice.	ROCK2 ROCK1	4.84e-06	2	77	2	8772201
Pubmed	Electrophysiological analyses of transgenic mice overexpressing KCNJ8 with S422L mutation in cardiomyocytes.	KCNJ8 NLRP3	4.84e-06	2	77	2	28928055
Pubmed	Locus category based analysis of a large genome-wide association study of rheumatoid arthritis.	TEC TXK	4.84e-06	2	77	2	20639398
Pubmed	ROCK isoform regulation of myosin phosphatase and contractility in vascular smooth muscle cells.	ROCK2 ROCK1	4.84e-06	2	77	2	19131646
Pubmed	Fasudil or genetic depletion of ROCK1 or ROCK2 induces anxiety-like behaviors.	ROCK2 ROCK1	4.84e-06	2	77	2	31302146
Pubmed	Rho kinases regulate the renewal and neural differentiation of embryonic stem cells in a cell plating density-dependent manner.	ROCK2 ROCK1	4.84e-06	2	77	2	20169147
Pubmed	ROCK2 Regulates Monocyte Migration and Cell to Cell Adhesion in Vascular Endothelial Cells.	ROCK2 ROCK1	4.84e-06	2	77	2	30884801
Pubmed	Rho-associated kinases play a role in endocardial cell differentiation and migration.	ROCK2 ROCK1	4.84e-06	2	77	2	15464581
Interaction	FYN interactions	PTPRD NTRK2 RPS6KA2 PRKACA PRKACB PRKCI PRKCQ FGFR2 PRPF8 ECT2 ITK TXK	3.79e-08	431	72	12	int:FYN
Interaction	PRKDC interactions	FLII RPS6KA2 PRKACA PRKACB ROCK1 AKT2 FGFR2 STK32C PRPF8 ECT2 SLX4 EPHA1	5.94e-06	695	72	12	int:PRKDC
Interaction	HSP90AA1 interactions	TNK1 FLII BMX NTRK2 RPS6KA2 PRKACA PRKACB PRKCI AKT2 PRKCQ STK32C PRPF8 SLX4 NLRP3 ITK EPHA1	7.52e-06	1263	72	16	int:HSP90AA1
Interaction	CDC37 interactions	BMX NTRK2 RPS6KA2 PRKACA PRKCI AKT2 FGFR2 STK32C PRPF8 ITK EPHA1	1.70e-05	645	72	11	int:CDC37
Interaction	IL1RAP interactions	GALNT10 PTPRD PRKCI IL1RL2	1.82e-05	44	72	4	int:IL1RAP
Interaction	EPHA8 interactions	BMX PTPRD OSBPL2 FGFR2 TEC TXK	3.15e-05	169	72	6	int:EPHA8
Interaction	KCNMB3 interactions	XYLT2 TMEM120A ZMPSTE24 KCNJ8	3.84e-05	53	72	4	int:KCNMB3
Interaction	RPE interactions	PRKACA PRKACB AKT2 TEC	5.49e-05	58	72	4	int:RPE
Interaction	TBX21 interactions	TEC ITK TXK	8.39e-05	24	72	3	int:TBX21
Interaction	TCTN2 interactions	TMEM120B ZMPSTE24 KCNJ8 SURF4 GLB1L2 SCD5 WLS	1.06e-04	304	72	7	int:TCTN2
Interaction	PIK3R1 interactions	NTRK2 RPS6KA2 FGFR2 TEC PRPF8 ITK EPHA1 TXK	1.09e-04	412	72	8	int:PIK3R1
Cytoband	4p12	TEC TXK	5.17e-04	20	77	2	4p12
Cytoband	20q11.2	GDF5 DNMT3B	9.48e-04	27	77	2	20q11.2
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ROCK2 BMX ROCK1 AKT2 TEC ITK	1.48e-05	206	47	6	682
GeneFamily	Polypeptide N-acetylgalactosaminyltransferases	GALNTL6 GALNT10 GALNT16	1.82e-05	20	47	3	433
GeneFamily	SH2 domain containing	BMX TEC ITK TXK	1.36e-04	101	47	4	741
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	NTRK2 FGFR2 PTK7	1.52e-04	40	47	3	321
GeneFamily	Potassium voltage-gated channel subfamily J	KCNJ6 KCNJ8	7.75e-04	16	47	2	276
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	PTPRD NTRK2 FGFR2 PTK7	8.02e-04	161	47	4	593
GeneFamily	Solute carriers	SLC7A2 SLC7A3 SLC16A4 SLC12A8 SLC47A2	3.50e-03	395	47	5	752
Coexpression	HE_LIM_SUN_FETAL_LUNG_C2_HSC_ELP_CELL	MAST4 NDUFAF7 TM7SF3 PRKACB KCNN4 PRKCQ TEC PTK7 DNMT3B	3.02e-06	412	76	9	M45729
Coexpression	GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_UP	SLC7A2 RPS6KA2 SURF4 KCNN4 ITK PTK7	2.57e-05	200	76	6	M7135
Coexpression	DING_LUNG_CANCER_BY_MUTATION_RATE	MAST4 PTPRD NTRK2	2.58e-05	20	76	3	M1189
CoexpressionAtlas	alpha beta T cells, T.4.LN.BDC, 4+ 8- BDC+, Lymph Node, avg-3	XYLT2 GALNT10 PRKACA KCNN4 PRKCQ IL1RL2 ITK TXK	3.52e-05	354	75	8	GSM605753_500
CoexpressionAtlas	gamma delta T cells, Tgd.vg5-.IEL, CD8a+ CD8b- TCRgd+ Vg5- CD44lo, Small Intestine, avg-3	PRKACB SREBF2 PGM2L1 PRKCQ STK32C WLS ITK TXK	9.04e-05	405	75	8	GSM605811_500
CoexpressionAtlas	alpha beta T cells, T.4.PLN.BDC, 4+ 8- BDC+, Lymph Node, avg-3	KCNN4 PRKCQ ITK TXK	1.44e-04	75	75	4	GSM605758_100
CoexpressionAtlas	alpha beta T cells, T.4.Pa.BDC, 4+ 8- BDC+, Pancreas, avg-2	KCNN4 PRKCQ ITK TXK	1.68e-04	78	75	4	GSM605756_100
CoexpressionAtlas	alpha beta T cells, T.4Nve.LN, 4+ 8- 25- 62Lhi 44lo, Lymph Node, avg-3	XYLT2 GALNT10 KCNN4 PRKCQ IL1RL2 ITK TXK	1.84e-04	336	75	7	GSM538374_500
CoexpressionAtlas	alpha beta T cells, T.4.PLN.BDC, 4+ 8- BDC+, Lymph Node, avg-3	XYLT2 GALNT10 PRKACA KCNN4 PRKCQ ITK TXK	1.84e-04	336	75	7	GSM605758_500
CoexpressionAtlas	alpha beta T cells, T.4.TI.B16, 4+ 8- TCR+ 45+, B16 Melanoma Tumor, avg-3	XYLT2 GALNT10 KCNN4 PRKCQ IL1RL2 ITK TXK	1.91e-04	338	75	7	GSM605763_500
CoexpressionAtlas	CD positive, CD4 Test DB, 4+8-B220-, Spleen, avg-1	XYLT2 GALNT10 KCNN4 PRKCQ IL1RL2 ITK TXK	1.91e-04	338	75	7	GSM403987_500
CoexpressionAtlas	gamma delta T cells, Tgd.vg1+vd6-.Th, TCRd+ Vg1.1+, Thymus, avg-3	PRKCQ ECT2 ITK TXK	1.94e-04	81	75	4	GSM605781_100
CoexpressionAtlas	alpha beta T cells, T.4Nve.Sp, 4+ 8- 25- 62Lhi 44lo, Spleen, avg-4	XYLT2 GALNT10 KCNN4 PRKCQ IL1RL2 ITK TXK	1.95e-04	339	75	7	GSM538382_500
CoexpressionAtlas	alpha beta T cells, T.4Nve.MLN, 4+ 8- 25- 62Lhi 44lo, Lymph Node, avg-3	XYLT2 GALNT10 KCNN4 PRKCQ IL1RL2 ITK TXK	2.13e-04	344	75	7	GSM538377_500
CoexpressionAtlas	gamma delta T cells, Tgd.Th, TCRd+ CD3e+, Thymus, avg-3	PRKCQ ECT2 ITK TXK	2.24e-04	84	75	4	GSM476675_100
CoexpressionAtlas	gamma delta T cells, Tgd.vg2-24ahi.Th, TCRd+ Vg2- CD24+, Thymus, avg-2	PRKCQ ECT2 ITK TXK	2.56e-04	87	75	4	GSM476658_100
CoexpressionAtlas	CD positive, CD4 Test NA, 4+8-B220-, Spleen, avg-1	XYLT2 GALNT10 KCNN4 PRKCQ IL1RL2 ITK TXK	2.67e-04	357	75	7	GSM403986_500
CoexpressionAtlas	CD positive, CD4 Test JS, 4+8-B220-, Spleen, avg-3	XYLT2 GALNT10 KCNN4 PRKCQ IL1RL2 ITK TXK	2.76e-04	359	75	7	GSM404000_500
CoexpressionAtlas	gamma delta T cells, Tgd.vg2+24ahi.e17.Th, TCRd+ Vg2+ CD24+, Fetal Thymus, avg-3	PRKCQ ECT2 ITK TXK	2.79e-04	89	75	4	GSM476660_100
CoexpressionAtlas	alpha beta T cells, T.4FP3-.Sp, 4+ 8- GFP- 44lo, Spleen, avg-3	XYLT2 GALNT10 KCNN4 PRKCQ IL1RL2 ITK TXK	3.00e-04	364	75	7	GSM605766_500
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#3_top-relative-expression-ranked_200	PRSS35 KCNJ8 GLB1L2	5.05e-04	44	75	3	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k3_200
CoexpressionAtlas	gamma delta T cells, Tgd.vg5-.act.IEL, CD8a+ CD8b- TCRd+ Vg5- CD44hi, Small Intestine, avg-3	PRKACB PGM2L1 PRKCQ STK32C WLS ITK TXK	5.43e-04	402	75	7	GSM605808_500
CoexpressionAtlas	alpha beta T cells, T.4int8+.Th, 4int 8+ TCRhi, Thymus, avg-3	XYLT2 TMEM120B KCNN4 PRKCQ ITK TXK	5.53e-04	289	75	6	GSM399367_500
CoexpressionAtlas	gamma delta T cells, Tgd.vg5+.act.IEL, CD8a+ CD8b- TCRd+ Vg5+ CD44hi, Small Intestine, avg-3	PRKACB PGM2L1 PRKCQ STK32C WLS ITK TXK	6.10e-04	410	75	7	GSM605802_500
CoexpressionAtlas	CD positive, CD4 Control, 4+ 8- B220-, Spleen, avg-4	PRKCQ ITK TXK	6.14e-04	47	75	3	GSM403995_100
CoexpressionAtlas	NK cells, NK.MCMV7.Sp, CD3-,NK1.1+, Spleen, avg-3	KCNJ8 PRKACB PGM2L1 PRKCQ STK32C ITK TXK	6.19e-04	411	75	7	GSM538312_500
CoexpressionAtlas	gamma delta T cells, Tgd.vg2+24ahi.Th.TCRbko, TCRd+ Vg2+ CD24+, Thymus, avg-3	GALNT10 TMEM120B KCNN4 PRKCQ ECT2 ITK TXK	6.28e-04	412	75	7	GSM605793_500
CoexpressionAtlas	gamma delta T cells, Tgd.vg5+.IEL, CD8a+ CD8b- TCRd+ Vg5+ CD44lo, Small Intestine, avg-3	PRKACB SREBF2 PRKCQ STK32C WLS ITK TXK	6.55e-04	415	75	7	GSM605805_500
CoexpressionAtlas	alpha beta T cells, T.4+8int.Th, 4+ 8int TCRhi, Thymus, avg-3	XYLT2 GALNT10 KCNN4 PRKCQ ITK TXK	6.96e-04	302	75	6	GSM399362_500
CoexpressionAtlas	gamma delta T cells, Tgd.vg2+24ahi.Th, TCRd+ Vg2+ CD24+, Thymus, avg-3	GALNT10 TMEM120B KCNN4 PRKCQ ECT2 ITK TXK	7.33e-04	423	75	7	GSM476655_500
CoexpressionAtlas	alpha beta T cells, T.DP69+.Th, 4+ 8+ TCRlo/int 69+, Thymus, avg-3	XYLT2 TMEM120B KCNN4 PRKCQ ITK TXK	7.33e-04	305	75	6	GSM399394_500
CoexpressionAtlas	alpha beta T cells, T.4Nve.LN, 4+ 8- 25- 62Lhi 44lo, Lymph Node, avg-3	PRKCQ ITK TXK	7.80e-04	51	75	3	GSM538374_100
CoexpressionAtlas	alpha beta T cells, T.8SP24int.Th, 4- 8+ TCRhi 24int, Thymus, avg-3	PRKCQ ITK TXK	8.26e-04	52	75	3	GSM399382_100
CoexpressionAtlas	alpha beta T cells, T.4Nve.MLN, 4+ 8- 25- 62Lhi 44lo, Lymph Node, avg-3	PRKCQ ITK TXK	8.26e-04	52	75	3	GSM538377_100
CoexpressionAtlas	alpha beta T cells, T.4Nve.PP, TCR+ CD4+ CD44low CD62Lhigh, Peyer's Patch, avg-2	PRKCQ ITK TXK	8.73e-04	53	75	3	GSM538380_100
CoexpressionAtlas	alpha beta T cells, T.4SP24-.Th, 4+ 8- TCRhi 24-/lo, Thymus, avg-3	PRKCQ ITK TXK	8.73e-04	53	75	3	GSM399370_100
CoexpressionAtlas	alpha beta T cells, T.4Nve.Sp, 4+ 8- 25- 62Lhi 44lo, Spleen, avg-4	PRKCQ ITK TXK	9.22e-04	54	75	3	GSM538382_100
CoexpressionAtlas	alpha beta T cells, T.4int8+.Th, 4int 8+ TCRhi, Thymus, avg-3	PRKCQ ITK TXK	9.22e-04	54	75	3	GSM399367_100
CoexpressionAtlas	CD positive, CD4 Test CJ, 4+8-B220-, Spleen, avg-2	PRKCQ ITK TXK	9.73e-04	55	75	3	GSM404003_100
CoexpressionAtlas	CD positive, CD4 Control, 4+8-B220-, Spleen, avg-2	PRKCQ ITK TXK	9.73e-04	55	75	3	GSM403994_100
CoexpressionAtlas	alpha beta T cells, T.4SP24int.Th, 4+ 8- TCRhi 24int, Thymus, avg-3	XYLT2 GALNT10 KCNN4 PRKCQ ITK TXK	1.00e-03	324	75	6	GSM399373_500
CoexpressionAtlas	CD positive, CD4 Test NA, 4+8-B220-, Spleen, avg-1	PRKCQ ITK TXK	1.03e-03	56	75	3	GSM403986_100
CoexpressionAtlas	alpha beta T cells, T.4+8int.Th, 4+ 8int TCRhi, Thymus, avg-3	PRKCQ ITK TXK	1.03e-03	56	75	3	GSM399362_100
CoexpressionAtlas	alpha beta T cells, T.4.Pa.BDC, 4+ 8- BDC+, Pancreas, avg-2	GALNT10 PRKACA KCNN4 PRKCQ ITK TXK	1.07e-03	328	75	6	GSM605756_500
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_500	PRSS35 NTRK2 KCNJ8 GLB1L2	1.07e-03	127	75	4	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k2_500
CoexpressionAtlas	alpha beta T cells, T.4.TI.B16, 4+ 8- TCR+ 45+, B16 Melanoma Tumor, avg-3	PRKCQ ITK TXK	1.08e-03	57	75	3	GSM605763_100
CoexpressionAtlas	alpha beta T cells, T.DP69+.Th, 4+ 8+ TCRlo/int 69+, Thymus, avg-3	PRKCQ ITK TXK	1.08e-03	57	75	3	GSM399394_100
CoexpressionAtlas	CD positive, CD4 Test DB, 4+8-B220-, Spleen, avg-1	PRKCQ ITK TXK	1.14e-03	58	75	3	GSM403987_100
CoexpressionAtlas	alpha beta T cells, T.8SP69+.Th, 4- 8+ TCRhi 69+, Thymus, avg-3	PRKCQ ITK TXK	1.14e-03	58	75	3	GSM399385_100
CoexpressionAtlas	alpha beta T cells, T.4Mem.LN, TCRb CD44high CD122lo CD4, Lymph Node, avg-3	PRKCQ ITK TXK	1.14e-03	58	75	3	GSM538362_100
CoexpressionAtlas	alpha beta T cells, T.4SP69+.Th, 4+ 8- TCRhi 69+, Thymus, avg-3	PRKCQ ITK TXK	1.19e-03	59	75	3	GSM399376_100
CoexpressionAtlas	alpha beta T cells, T.4FP3-.Sp, 4+ 8- GFP- 44lo, Spleen, avg-3	PRKCQ ITK TXK	1.19e-03	59	75	3	GSM605766_100
CoexpressionAtlas	alpha beta T cells, T.4Mem.Sp, 4+ 8- 25- 44hi 122lo, Spleen, avg-3	PRKCQ ITK TXK	1.25e-03	60	75	3	GSM538365_100
CoexpressionAtlas	alpha beta T cells, T.8SP24-.Th, 4- 8+ TCRhi 24-/lo, Thymus, avg-3	PRKCQ ITK TXK	1.25e-03	60	75	3	GSM399379_100
CoexpressionAtlas	alpha beta T cells, T.4SP24int.Th, 4+ 8- TCRhi 24int, Thymus, avg-3	PRKCQ ITK TXK	1.25e-03	60	75	3	GSM399373_100
CoexpressionAtlas	alpha beta T cells, T.4Mem44h62l.Sp, CD4 TCRb CD44hi CD62Llo, Spleen, avg-3	PRKCQ ITK TXK	1.25e-03	60	75	3	GSM538371_100
CoexpressionAtlas	alpha beta T cells, T.8SP24int.Th, 4- 8+ TCRhi 24int, Thymus, avg-3	XYLT2 TMEM120B KCNN4 PRKCQ ITK TXK	1.26e-03	339	75	6	GSM399382_500
CoexpressionAtlas	CD positive, CD4 Test JS, 4+8-B220-, Spleen, avg-3	PRKCQ ITK TXK	1.31e-03	61	75	3	GSM404000_100
CoexpressionAtlas	alpha beta T cells, T.8Mem.LN, CD8 TCRb CD44high CD122high, Lymph Node, avg-3	PRKCQ ITK TXK	1.38e-03	62	75	3	GSM538395_100
CoexpressionAtlas	alpha beta T cells, T.8SP24-.Th, 4- 8+ TCRhi 24-/lo, Thymus, avg-3	XYLT2 GALNT10 KCNN4 PRKCQ ITK TXK	1.51e-03	351	75	6	GSM399379_500
CoexpressionAtlas	alpha beta T cells, T.8Mem.Sp, 4- 8+ 25- 44hi 122hi, Spleen, avg-3	PRKCQ ITK TXK	1.51e-03	64	75	3	GSM538398_100
CoexpressionAtlas	alpha beta T cells, T.8Nve.LN, 4- 8+ 25- 62Lhi 44lo, Lymph Node, avg-3	PRKCQ ITK TXK	1.58e-03	65	75	3	GSM538406_100
CoexpressionAtlas	alpha beta T cells, T.8Nve.MLN, 4- 8+ 25- 62Lhi 44lo, Lymph Node, avg-3	XYLT2 GALNT10 KCNN4 PRKCQ ITK TXK	1.62e-03	356	75	6	GSM538409_500
CoexpressionAtlas	alpha beta T cells, T.8.Sp.B16, 4- 8+ TCR+ 45+, B16 Melanoma Spleen, avg-3	PRKCQ ITK TXK	1.65e-03	66	75	3	GSM605770_100
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_top-relative-expression-ranked_1000	TNK1 PTPRD PGM2L1 PRKCI SLC12A8 FGFR2 GLB1L2 TEC EPHA1	1.67e-03	780	75	9	gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_1000
CoexpressionAtlas	alpha beta T cells, T.8Nve.MLN, 4- 8+ 25- 62Lhi 44lo, Lymph Node, avg-3	PRKCQ ITK TXK	1.72e-03	67	75	3	GSM538409_100
CoexpressionAtlas	alpha beta T cells, T.8Nve.PP, TCRb+ CD8+ CD44low CD62Lhigh, Peyer's Patch, avg-1	PRKCQ ITK TXK	1.72e-03	67	75	3	GSM538414_100
CoexpressionAtlas	gamma delta T cells, Tgd.vg1+vd6-.Th.TCRbko, TCRd+ Vg1.1+, Thymus, avg-3	GALNT10 KCNN4 PRKCQ ECT2 ITK TXK	1.76e-03	362	75	6	GSM605784_500
CoexpressionAtlas	alpha beta T cells, T.8SP69+.Th, 4- 8+ TCRhi 69+, Thymus, avg-3	XYLT2 TMEM120B KCNN4 PRKCQ ITK TXK	1.76e-03	362	75	6	GSM399385_500
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_200	PRSS35 KCNJ8 RESP18 GLB1L2	1.83e-03	147	75	4	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_200
CoexpressionAtlas	alpha beta T cells, T.4SP24-.Th, 4+ 8- TCRhi 24-/lo, Thymus, avg-3	XYLT2 GALNT10 KCNN4 PRKCQ ITK TXK	1.84e-03	365	75	6	GSM399370_500
CoexpressionAtlas	alpha beta T cells, T.4SP69+.Th, 4+ 8- TCRhi 69+, Thymus, avg-3	XYLT2 GALNT10 KCNN4 PRKCQ ITK TXK	1.84e-03	365	75	6	GSM399376_500
CoexpressionAtlas	alpha beta T cells, T.8Nve.PP, TCRb+ CD8+ CD44low CD62L high, Peyer's Patch, avg-1	PRKCQ ITK TXK	1.88e-03	69	75	3	GSM538413_100
CoexpressionAtlas	alpha beta T cells, T.8Nve.Sp, 4- 8+ 25- 62Lhi 44lo, Spleen, avg-3	PRKCQ ITK TXK	1.88e-03	69	75	3	GSM538415_100
CoexpressionAtlas	alpha beta T cells, T.8Nve.PP, TCR+ CD8+ CD44low CD62Lhigh, Peyer's Patch, avg-1	PRKCQ ITK TXK	1.88e-03	69	75	3	GSM538412_100
CoexpressionAtlas	CD positive, T.8Nve.Sp.OT1, CD8+ CD45.1+, Spleen, avg-3	PRKCQ ITK TXK	1.95e-03	70	75	3	GSM605909_100
CoexpressionAtlas	gamma delta T cells, Tgd.vg1+vd6+.Th, TCRd+ Vd6.3+ Vg1.1+, Thymus, avg-1	PRKCQ ITK TXK	1.95e-03	70	75	3	GSM605775_100
CoexpressionAtlas	gamma delta T cells, Tgd.vg1+vd6+.Th.TCRbko, TCRd+ Vg1.1+ Vd6.3+, Thymus, avg-3	PRKCQ ITK TXK	2.04e-03	71	75	3	GSM605778_100
CoexpressionAtlas	NK cells, NK.DAP10-.Sp, NK1.1+ TCRb-, Spleen, avg-3	PRKCQ ITK TXK	2.04e-03	71	75	3	GSM538294_100
CoexpressionAtlas	NK cells, NK.49CI-.Sp, NK1.1+ CD3- Ly49C/I-, Spleen, avg-3	PRKCQ ITK TXK	2.04e-03	71	75	3	GSM538288_100
CoexpressionAtlas	NK cells, NK.49CI+.Sp, NK1.1+ CD3- Ly49C/I+, Spleen, avg-3	PRKCQ ITK TXK	2.04e-03	71	75	3	GSM538285_100
CoexpressionAtlas	dev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000	PRSS35 SLC7A2 ZMPSTE24 SLC16A4 TM7SF3 FGFR2 GLB1L2 FGGY TMEM50B	2.05e-03	804	75	9	gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_1000
CoexpressionAtlas	gamma delta T cells, Tgd.vg2+.Sp, TCRd+ Vg2+ CD44-, Spleen, avg-3	PRKCQ ITK TXK	2.12e-03	72	75	3	GSM605787_100
CoexpressionAtlas	NK cells, NK.49H+.Sp, NK1.1+ Ly49H+, Spleen, avg-3	PRKCQ ITK TXK	2.12e-03	72	75	3	GSM605814_100
CoexpressionAtlas	NK cells, NK.MCMV7.Sp, CD3-,NK1.1+, Spleen, avg-3	PRKCQ ITK TXK	2.12e-03	72	75	3	GSM538312_100
CoexpressionAtlas	NK cells, NK.MCMV1.Sp, CD3-,NK1.1+, Spleen, avg-3	PRKCQ ITK TXK	2.20e-03	73	75	3	GSM538309_100
CoexpressionAtlas	alpha beta T cells, T.4FP3+25+.Sp, 4+ 8- GFP+ 25+, Spleen, avg-3	PRKCQ ITK TXK	2.20e-03	73	75	3	GSM399365_100
CoexpressionAtlas	NK cells, NK.Sp, NK1.1+, Spleen, avg-3	PRKCQ ITK TXK	2.20e-03	73	75	3	GSM538315_100
CoexpressionAtlas	alpha beta T cells, T.DPsm.Th, 4+ 8+ TCR-/lo FSClo, Thymus, avg-3	PRKCQ ITK TXK	2.20e-03	73	75	3	GSM399400_100
CoexpressionAtlas	NK cells, NK.b2m-.Sp, NK1.1+ TCRb-, Spleen, avg-3	PRKCQ ITK TXK	2.20e-03	73	75	3	GSM538291_100
CoexpressionAtlas	alpha beta T cells, T.8Mem.Sp.OT1.d100.LisOva, CD8+ CD45.1+, Spleen, avg-3	PRKCQ ITK TXK	2.20e-03	73	75	3	GSM605904_100
CoexpressionAtlas	NK cells, NK.DAP12-.Sp, NK1.1+ CD3-, Spleen, avg-3	PRKCQ ITK TXK	2.29e-03	74	75	3	GSM538297_100
CoexpressionAtlas	NK cells, NK.49H-.Sp, NK1.1+, Spleen, avg-3	PRKCQ ITK TXK	2.29e-03	74	75	3	GSM605817_100
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000	PRSS35 TMTC1 NTRK2 KCNJ8 GLB1L2	2.31e-03	261	75	5	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_1000
CoexpressionAtlas	NK cells, NK.H+.MCMV1.Sp, NK1.1+ TCRb- Ly49H+, Spleen, avg-3	PRKCQ ITK TXK	2.38e-03	75	75	3	GSM538300_100
CoexpressionAtlas	alpha beta T cells, T.4.LN.BDC, 4+ 8- BDC+, Lymph Node, avg-3	PRKCQ ITK TXK	2.38e-03	75	75	3	GSM605753_100
CoexpressionAtlas	alpha beta T cells, T.8Eff.Sp.OT1.d15.VSVOva, CD8+ CD45.1+, Spleen, avg-2	PRKCQ ITK TXK	2.38e-03	75	75	3	GSM538385_100
CoexpressionAtlas	NK cells, NK.H+.MCMV7.Sp, NK1.1+ TCRb- Ly49H+, Spleen, avg-3	PRKCQ ITK TXK	2.38e-03	75	75	3	GSM538303_100
CoexpressionAtlas	NK cells, NK.49CI+.Sp, NK1.1+ CD3- Ly49C/I+, Spleen, avg-3	KCNJ8 PRKACB PRKCQ STK32C ITK TXK	2.40e-03	385	75	6	GSM538285_500
CoexpressionAtlas	gamma delta T cells, Tgd.vg5+.IEL, CD8a+ CD8b- TCRd+ Vg5+ CD44lo, Small Intestine, avg-3	STK32C ITK TXK	2.47e-03	76	75	3	GSM605805_100
CoexpressionAtlas	alpha beta T cells, T.8Mem.Sp.OT1.d45.VSVOva, CD8+ CD45.1+, Spleen, avg-3	PRKCQ ITK TXK	2.47e-03	76	75	3	GSM538403_100
CoexpressionAtlas	gamma delta T cells, Tgd.vg2-.act.Sp, TCRd+ Vg2- CD44+, Spleen, avg-3	PRKCQ ITK TXK	2.47e-03	76	75	3	GSM476681_100
CoexpressionAtlas	NK cells, NK.b2m-.Sp, NK1.1+ TCRb-, Spleen, avg-3	KCNJ8 PRKACB PRKCQ STK32C ITK TXK	2.56e-03	390	75	6	GSM538291_500
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM5 NTRK2 RPS6KA2 PRKACB GLB1L2 WLS UNC80	3.94e-08	192	76	7	5b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A2 TRPM5 NTRK2 PRKACB RESP18 WLS UNC80	4.23e-08	194	76	7	92b39a935e8c577eb1123d706d168fa13cf3344c
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Natural_Killer_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 KCNN4 PRKCQ STK32C ITK TXK	5.36e-07	174	76	6	5b00a795a9dd1a77305fcac5017cb276afdc1a27
ToppCell	droplet-Lung-nan-18m-Lymphocytic-mature_NK_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 KCNN4 PRKCQ STK32C ITK TXK	5.36e-07	174	76	6	3340b44c77f55244e3c2e2ea479d42563f937040
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNJ8 KCNN4 PRKCQ STK32C ITK TXK	6.12e-07	178	76	6	28bb1e3e447261d0cb47e2b6343b17b2d74db525
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l4\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNJ8 KCNN4 PRKCQ STK32C ITK TXK	6.33e-07	179	76	6	ac0c257e63a5994282d8b350c1b517cc3fbee52a
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM5 NTRK2 RPS6KA2 PRKACB WLS UNC80	9.24e-07	191	76	6	f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A2 TRPM5 NTRK2 PRKACB RESP18 UNC80	9.53e-07	192	76	6	1304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	BMX PTPRD NTRK2 TNFAIP6 GALNT16 UNC80	1.04e-06	195	76	6	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	BMX PTPRD NTRK2 TNFAIP6 GALNT16 UNC80	1.04e-06	195	76	6	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRD TM7SF3 PRKCQ FGFR2 TNFAIP6 SCD5	1.21e-06	200	76	6	56f1f007ba8c9188a4b10e52744f1e50dc0f155a
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 PRKCQ STK32C ITK TXK	7.57e-06	158	76	5	9f0987eaf1766aadb5714b68df7a5d310ea5a57a
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 PRKCQ STK32C ITK TXK	7.81e-06	159	76	5	94bc6ab248a8f02ccbc0facd24e0c7e9fda687d2
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 PRKCQ STK32C ITK TXK	9.07e-06	164	76	5	9fed5df40f50bde35db8bf89c291cbdc0e104112
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 PRKCQ STK32C ITK TXK	9.07e-06	164	76	5	e712d6b89461f741dbd773ba9a27ecaddf97cbaa
ToppCell	facs-BAT-Fat-18m-Lymphocytic-NK_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 PRKCQ STK32C ITK TXK	9.07e-06	164	76	5	ab9c17f86b98e1a4d5db1bd3086edab1320ebda8
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNN4 PRKCQ TEC ITK TXK	1.02e-05	168	76	5	68ee3b3b012b56584e313813feb16e632e3f72d2
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PRSS35 SLC7A2 TRPM5 SLC16A4 UNC80	1.05e-05	169	76	5	58e22f9119240664515fe91ca53812611a8f17d6
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNN4 PRKCQ STK32C ITK TXK	1.08e-05	170	76	5	d74fbd995a8a37fc237f7147d398357b811d6452
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l5\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNN4 PRKCQ TEC ITK TXK	1.08e-05	170	76	5	67e78e3c1d4cd3c6eaa5d0a9785b6cd8a3b08039
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNN4 PRKCQ TEC ITK TXK	1.21e-05	174	76	5	fedadde222df1952d6456f4f3413c01579146e1f
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNN4 PRKCQ STK32C ITK TXK	1.21e-05	174	76	5	262d14b42bc5ec2c8d5f33a1a0eb49a8e38dd0f0
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNN4 PRKCQ TEC ITK TXK	1.21e-05	174	76	5	e69a011ae9698368923223d3af3243e609c08c83
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAST4 RPS6KA2 SREBF2 BEST3 SYNGR4	1.21e-05	174	76	5	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	facs-BAT-Fat-18m-Lymphocytic-T_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 KCNN4 PRKCQ ITK TXK	1.24e-05	175	76	5	bf1ef77d5fed2135ac83a4f7e445ab59d1538696
ToppCell	Posterior_cortex-Macroglia\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TM7SF3 PRKCQ FGFR2 TNFAIP6 SCD5	1.24e-05	175	76	5	8bc7a3856d04692989b2a1675ea6d9392261d55a
ToppCell	droplet-Kidney-KIDNEY-1m-Lymphocytic-T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNN4 PGM2L1 PRKCQ ITK TXK	1.31e-05	177	76	5	36da06ca9577cdb7c7b5114e604f6546b9765c08
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAST4 NTRK2 PRKCQ SCD5 GALNT16	1.35e-05	178	76	5	dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNN4 PRKCQ RESP18 ITK TXK	1.42e-05	180	76	5	03e3067ee313e8c40b702b9bc9981f9859d045a2
ToppCell	facs-Spleen-nan-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 KCNN4 PRKCQ ITK TXK	1.42e-05	180	76	5	407fd8f61a757626e082b6e2eefd3a33276e6b71
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAST4 PTPRD SLC16A4 FGGY SLC47A2	1.46e-05	181	76	5	9542c19edc9bd2cba68c01c2a8407705398e3011
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAST4 PTPRD SLC16A4 FGGY SLC47A2	1.46e-05	181	76	5	8f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCell	NS-critical-d_0-4-Lymphoid-Treg\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PRSS35 TMEM120B PRKACB PRKCQ ITK	1.54e-05	183	76	5	f478dfa231fc1b12ead0183cc9d22077cdf43d1f
ToppCell	facs-Spleen-nan-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT10 KCNN4 PRKCQ ITK TXK	1.58e-05	184	76	5	c37c623c4a5ff1628486d8a6461fa355ad5c264c
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XYLT2 PRKACB KCNN4 PRKCQ ITK	1.62e-05	185	76	5	a2cae8c657e4f4d121476798e424876f7e247973
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XYLT2 PRKACB KCNN4 PRKCQ ITK	1.62e-05	185	76	5	d50406a9a5b8d75110ba5985741aa2293950c543
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAST4 NTRK2 PRKCQ SCD5 WLS	1.67e-05	186	76	5	1850583d23903d08226aeb0edb3e07b0994330e4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAST4 NTRK2 PRKCQ SCD5 WLS	1.67e-05	186	76	5	4dafc215c42e7949f932a3627359c107943b5d6b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAST4 PTPRD SLC12A8 FGFR2 SLC47A2	1.67e-05	186	76	5	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAST4 PTPRD TM7SF3 FGGY SLC47A2	1.71e-05	187	76	5	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAST4 PTPRD TM7SF3 FGGY SLC47A2	1.71e-05	187	76	5	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	facs-MAT-Fat-3m\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT10 TMTC1 NTRK2 TM7SF3 PRPF8	1.75e-05	188	76	5	7da9750255efbc5cf9aed7e3105a337fac63b9f0
ToppCell	human_hepatoblastoma-Endothelial_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	TMTC1 MAST4 RPS6KA2 PGM2L1 SCD5	1.85e-05	190	76	5	8d6ef93d69e96cd6921816d152bea3b0710cf147
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT10 MAST4 NTRK2 PRKCQ SCD5	1.89e-05	191	76	5	963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM5 NTRK2 RPS6KA2 RESP18 UNC80	1.89e-05	191	76	5	3387b95a3f2445c672d407922fdce3a91eabaef8
ToppCell	NS-critical-d_07-13-Lymphoid-Treg\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GALNT10 PRKACB PRKCQ ITK TXK	1.94e-05	192	76	5	cd34defac6565d34db507918e791b09c79f7d1f8
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKT2 FGFR2 WLS GALNT16 PTK7	1.94e-05	192	76	5	0dc1f46e40346ed0b286e53b106a812441575100
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-midbrain/hindbrain_cells\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	MAST4 KCNJ6 PGM2L1 SCD5 WLS	2.14e-05	196	76	5	0767581b69bc7e6334d580ca02ed1e831b7b55da
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SURF4 PGM2L1 SLC12A8 TNFAIP6 PTK7	2.25e-05	198	76	5	c55608633f66e3d434c5d81324efb07c5120d2c2
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRD NTRK2 TM7SF3 FGFR2 SCD5	2.25e-05	198	76	5	a7e5de81eb7d3d23812c179a001adbaab1506596
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRD TM7SF3 FGFR2 TNFAIP6 SCD5	2.25e-05	198	76	5	731a90f7e68b19e387499d63e3979af78b503b0c
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SURF4 PGM2L1 SLC12A8 TNFAIP6 PTK7	2.25e-05	198	76	5	3e5459038fc6ed95f529eb4d1dc5113e16c19012
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRD TM7SF3 FGFR2 TNFAIP6 SCD5	2.30e-05	199	76	5	67d8c7e5356f5d409d4f98e8338cf6c499fd7aee
ToppCell	LPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PRKACB PRKCI PRKCQ SYNGR4 DNMT3B	2.36e-05	200	76	5	e4be88bcef2738915f711b32c95e9c613e7edf96
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRD TM7SF3 FGFR2 TNFAIP6 SCD5	2.36e-05	200	76	5	0e85c90719d9ec51a566e230c9dd2909d8df1f52
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GDF5 SLC7A2 AKT2 FGFR2	1.05e-04	143	76	4	b4ed3855652fdf32f97cb7c18cab4f4f4c24d5c7
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Met\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TMTC1 SLC7A3 PRKCQ WLS	1.11e-04	145	76	4	8abbc781f5f69f039617c29a5589d7b6950c2c40
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PRSS35 ROCK2 PGM2L1 GALNT16	1.17e-04	147	76	4	8f725ff8fb4ced5db2643e80669d3f7945b820ab
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Cpne7\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TMTC1 SLC7A3 PRKCQ WLS	1.23e-04	149	76	4	8638b3819193d11411df58964069fec583f617f4
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	XYLT2 ADPRH TNFAIP6 GALNT16	1.23e-04	149	76	4	68661c8facfb638560bb2e2c20d509941286dacb
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNN4 PRKCQ ITK TXK	1.23e-04	149	76	4	4fda987bc7bb6d1dbd41b8f1f8c1bc59613255a8
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TNK1 TM7SF3 TLE6 PRKCQ	1.26e-04	150	76	4	70ac8ae4b1683fb17278a8e4606f2fa0b94988c0
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-NP\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TMTC1 SLC7A3 PRKCQ WLS	1.33e-04	152	76	4	b6a7453fbf9f898e4f222b215907c9a110baa2f6
ToppCell	facs-Marrow-KLS-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TM7SF3 STK32C ITK TXK	1.40e-04	154	76	4	37765512dfae557b9f6eb30a29463b93682a4404
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	XYLT2 ADPRH TNFAIP6 GALNT16	1.40e-04	154	76	4	1c62290a2558fd6401b27de5a867d243b143b00a
ToppCell	facs-SCAT-Fat-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 PRKCQ STK32C TXK	1.51e-04	157	76	4	ad8c6eb34f5288288c4066119c17325afefbaafc
ToppCell	facs-GAT-Fat-18m-Lymphocytic-NK_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCQ STK32C ITK TXK	1.58e-04	159	76	4	796e63f6052189106359a4e01eae3e466bf1d593
ToppCell	droplet-Kidney-nan-18m-Lymphocytic-NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGM2L1 STK32C ITK TXK	1.62e-04	160	76	4	398f162e8a75c6cb5c3e4d1832e98d386e1f222b
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNJ8 SCD5 ITK TXK	1.62e-04	160	76	4	6b0faaa371650563f585722f5b2fb319e124ec38
ToppCell	droplet-Kidney-nan-18m-Lymphocytic-CD45____NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGM2L1 STK32C ITK TXK	1.62e-04	160	76	4	12aaab0291035f578e2433efd169ae72f393a5a5
ToppCell	droplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNJ8 PRKCQ STK32C TXK	1.66e-04	161	76	4	cd4a736d0cec31477c6e8d3b07a04ede1559854b
ToppCell	droplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNJ8 PRKCQ STK32C TXK	1.66e-04	161	76	4	28930ba576625b98cc15993d1499e9dc5edbb5a9
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNN4 PRKCQ ITK TXK	1.70e-04	162	76	4	b877b232f0a879a9058d81ad4730e7846484b7c3
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNN4 PRKCQ ITK TXK	1.70e-04	162	76	4	7384a4dd38ed68ca02a72df6deff4d34c9694ce1
ToppCell	droplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNJ8 PRKCQ STK32C TXK	1.70e-04	162	76	4	ccba6d8d644fe56060ad388ec3a062b7e3b9f086
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRSS35 KCNJ6 CHAC2 BEST3	1.70e-04	162	76	4	9a18286e361e1dd18e6f943ce27db58b199fb6e4
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 PRKCQ STK32C TXK	1.70e-04	162	76	4	66069146e2666d13c594bd76247893354a697c5d
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRSS35 KCNJ6 CHAC2 BEST3	1.70e-04	162	76	4	3395e4dffdb9304d157c325e1fc0f12b433c7bd3
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRSS35 KCNJ6 CHAC2 BEST3	1.70e-04	162	76	4	9522af31f6b2f3cb81b6b84bd08353eea504d1d6
ToppCell	367C-Lymphocytic-ILC-ILC-1\|367C / Donor, Lineage, Cell class and subclass (all cells)	PRKCQ SLX4 ITK EPHA1	1.70e-04	162	76	4	74cd0de957fdbe527656befd61f67d6814ce9e98
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRSS35 KCNJ6 CHAC2 BEST3	1.70e-04	162	76	4	40265af9b36fd144a8577b8dacccd4fc0888a593
ToppCell	droplet-Lung-nan-3m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 PRKCQ STK32C TXK	1.70e-04	162	76	4	4b490989005bb03d4e7bbea01580f8548eff150f
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 PRKCQ STK32C TXK	1.70e-04	162	76	4	e4a09bf1a51710f6c57e6e01edf8b4619459d96d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRKCQ ITK TMEM240 DNMT3B	1.74e-04	163	76	4	4dfd408aa700e307478ee35f6b902f68719d8d9e
ToppCell	droplet-Lung-nan-18m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 PRKCQ STK32C TXK	1.74e-04	163	76	4	801163c05f8fdacaebd0cb9b4c92741276bfa3e3
ToppCell	droplet-Fat-Scat-18m-Lymphocytic-T_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCQ STK32C ITK TXK	1.74e-04	163	76	4	b1a38985d0560dbc6ca66f711d52a208303860ca
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 KCNN4 PRKCQ TXK	1.78e-04	164	76	4	1a9b444d2c6abcc83d4355ec5228b27541df2bd0
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 PRKCQ STK32C TXK	1.78e-04	164	76	4	e9e5a1462d8ed60b2e5bf603c8c47eb85bce83d5
ToppCell	droplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNJ8 PRKCQ STK32C TXK	1.78e-04	164	76	4	c2cd4e4b88cc1b80a9494f59d31339007ff824c1
ToppCell	wk_20-22-Hematologic-Myeloid-HSC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	TM7SF3 KCNN4 TEC DNMT3B	1.78e-04	164	76	4	a35a0725b8bfe3cad5b85484217fd8a02bdee827
ToppCell	droplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNJ8 PRKCQ STK32C TXK	1.78e-04	164	76	4	d4d08353c7322f97ea07dd583b08661d635fff20
ToppCell	droplet-Lung-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNN4 PRKCQ ITK TXK	1.82e-04	165	76	4	54706631d819f401988e2c733dd6e59401a3585d
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 PRKCQ STK32C TXK	1.82e-04	165	76	4	80f82aaab48791cb06fcb2d8ed7821f162742385
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-Klrb1a/b/c(-)_NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCQ NLRP3 ITK TXK	1.82e-04	165	76	4	651d40eadb1b34de618af94c167f43635729d43f
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BMX TMEM120B MAST4 KCNN4	1.82e-04	165	76	4	62457b7b74c6eae42d91d65e7dc6df6bf8e061f7
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 PRKCQ STK32C TXK	1.82e-04	165	76	4	93ed399b8c6278e5f1528c07758fb502d80a1a8b
ToppCell	droplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCNJ8 PRKCQ STK32C TXK	1.82e-04	165	76	4	88745bf7ecb0f7fc93077cea20171d40535dd56b
ToppCell	droplet-Lung-nan-3m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNN4 PRKCQ ITK TXK	1.82e-04	165	76	4	28e3083ab90eb02141f844b7f8a218ec9c43dbf9
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRKCQ IL1RL2 ITK TXK	1.82e-04	165	76	4	ec16a4979b3f203c9f66ed387a7a17bf3a1d3f86
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ8 PRKCQ STK32C TXK	1.86e-04	166	76	4	3213466380becf0ee3d4d9a0776ccbb1ee4eccea
Drug	AH6809	ROCK2 PRKACA PRKACB KCNN4 ROCK1 PRKCI	8.31e-09	45	76	6	CID000119461
Drug	BiM4	ROCK2 NTRK2 RPS6KA2 PRKACA PRKACB KCNN4 ROCK1 PRKCI PRKCQ ITK	3.48e-08	283	76	10	CID000002399
Drug	Nicorette	ROCK2 GDF5 FLII KCNJ6 NTRK2 KCNJ8 PRKACA PRKACB MMP27 ROCK1 PRKCI PRKCQ	1.76e-07	529	76	12	CID000000942
Drug	potassium	ROCK2 SLC7A2 SLC7A3 TRPM5 KCNJ6 RPS6KA2 KCNJ8 PRKACA PRKACB KCNN4 ROCK1 PRKCI SLC12A8 AKT2 PRKCQ	1.00e-06	1008	76	15	CID000000813
Drug	imatinib	ROCK2 BMX NTRK2 ROCK1 PRKCQ FGFR2 TEC ITK EPHA1 TXK	1.63e-06	430	76	10	CID000005291
Drug	tautomycin	ROCK2 PRKACA ROCK1 PRKCI AKT2 PRKCQ	2.77e-06	118	76	6	CID000440646
Drug	AC1NSKHR	ROCK2 PRKACA ROCK1 PRKCI	4.93e-06	34	76	4	CID005311362
Drug	damnacanthal	ROCK2 ROCK1 TEC ITK	4.93e-06	34	76	4	CID000002948
Drug	glibenclamide	ROCK2 ZMPSTE24 KCNJ6 KCNJ8 PRKACA PRKACB KCNN4 ROCK1 PRKCI	5.07e-06	382	76	9	CID000003488
Drug	Rockout	ROCK2 ROCK1	1.10e-05	2	76	2	CID000644354
Drug	3,3-dimethylacryloyl chloride	ROCK2 ROCK1	1.10e-05	2	76	2	CID000102394
Drug	K 252	NTRK2 PRKACA PRKACB PRKCI PRKCQ	1.14e-05	88	76	5	CID000003813
Drug	B-43	ROCK2 ROCK1 EPHA1	1.27e-05	14	76	3	CID006603792
Drug	cBiMPS	ROCK2 PRKACA ROCK1	1.27e-05	14	76	3	CID005487206
Drug	tetraethylammonium	KCNJ6 KCNJ8 PRKACA PRKACB KCNN4 PRKCI PRKCQ	1.40e-05	236	76	7	CID000005413
Drug	wartmannin	ROCK2 BMX NTRK2 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI AKT2 PRKCQ TEC ITK	1.47e-05	811	76	12	CID000005691
Drug	NPC 15437	PRKACA PRKACB PRKCI PRKCQ	1.68e-05	46	76	4	CID000004548
Drug	GDP-b-S	ROCK2 KCNJ6 KCNJ8 PRKACA ROCK1 PRKCI	1.71e-05	162	76	6	CID000643998
Drug	Starlicide	NTRK2 PRKACA PRKACB DNMT3B	2.17e-05	49	76	4	CID000007255
Drug	Zm 241385	SLC7A3 NTRK2 PRKACA PRKACB	2.17e-05	49	76	4	CID000176407
Drug	4 alpha-phorbol	ROCK2 KCNJ6 PRKACA ROCK1 PRKCI	2.46e-05	103	76	5	CID000028683
Drug	LY294002	ROCK2 FLII NTRK2 RPS6KA2 PRKACA PRKACB SREBF2 ROCK1 PRKCI AKT2 TEC	3.66e-05	748	76	11	CID000003973
Drug	tyrphostin 23	ROCK2 PRKACA PRKACB ROCK1 PRKCI	4.36e-05	116	76	5	CID000002052
Drug	Rp-cAMPS	KCNJ6 KCNJ8 PRKACA PRKACB KCNN4 PRKCI	4.72e-05	194	76	6	CID006426631
Drug	Phentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A	XYLT2 TMEM120B MAST4 SLC16A4 SREBF2 EPHA1	5.00e-05	196	76	6	3971_DN
Drug	1,5-Isoquinolinediol; Up 200; 100uM; HL60; HG-U133A	ROCK2 TNK1 OSBPL2 MMP27 PRKCQ SCD5	5.14e-05	197	76	6	543_UP
Drug	Suprofen [40828-46-4]; Down 200; 15.4uM; HL60; HT_HG-U133A	TMEM120B SLC16A4 ADGRE3 FGFR2 TNFAIP6 SCD5	5.14e-05	197	76	6	3005_DN
Drug	Sisomicin sulfate [53179-09-2]; Down 200; 2.8uM; MCF7; HT_HG-U133A	XYLT2 TMEM120B SREBF2 SLC12A8 AKT2 DNMT3B	5.14e-05	197	76	6	2853_DN
Drug	Sp-8-Cl-cAMPS	NTRK2 PRKACA PRKACB	5.26e-05	22	76	3	CID000133987
Drug	Buflomedil hydrochloride [35543-24-9]; Up 200; 11.6uM; PC3; HT_HG-U133A	BMX SLC16A4 NTRK2 AKT2 FGFR2 NLRP3	5.29e-05	198	76	6	4258_UP
Drug	Avermectin B1 [71751-41-2]; Up 200; 4.8uM; PC3; HT_HG-U133A	TNK1 MAST4 NDUFAF7 KCNJ8 FGFR2 PTK7	5.44e-05	199	76	6	5864_UP
Drug	sodium	SLC7A2 SLC7A3 TRPM5 KCNJ6 KCNJ8 PRKACA PRKACB KCNN4 PRKCI SLC12A8 PRKCQ PRPF8	6.47e-05	944	76	12	CID000000923
Drug	diguanosine pentaphosphate	ROCK2 ROCK1	6.57e-05	4	76	2	CID004577574
Drug	Pkcs	ROCK2 SLC7A2 PRKACA ROCK1 PRKCI PRKCQ	7.52e-05	211	76	6	CID000164073
Drug	ponatinib	BMX NTRK2 FGFR2 EPHA1	7.94e-05	68	76	4	ctd:C545373
Drug	methacholine	ROCK2 ROCK1 PRKCI PRKCQ TEC ITK	8.77e-05	217	76	6	CID000001993
Drug	4 alpha-phorbol 12,13-didecanoate	KCNJ8 PRKACA PRKCI PRKCQ	8.89e-05	70	76	4	CID000452543
Drug	sulprostone	ROCK2 PRKACA PRKACB ROCK1	9.40e-05	71	76	4	CID005312153
Drug	carbachol	ROCK2 KCNJ6 RPS6KA2 KCNJ8 PRKACA PRKACB KCNN4 ROCK1 PRKCI PRKCQ	9.40e-05	688	76	10	CID000002551
Drug	K00077	KCNJ6 NTRK2 PRKACA PRKACB PRKCI PRKCQ	9.46e-05	220	76	6	CID006419759
Drug	calphostin C	ROCK2 PRKACA PRKACB ROCK1 PRKCI PRKCQ FGFR2 TEC	9.46e-05	431	76	8	CID000002533
Drug	L-Lysine	SLC7A2 SLC7A3	1.09e-04	5	76	2	DB00123
Drug	tetrahydrooxazine	ROCK2 ROCK1	1.09e-04	5	76	2	CID000449101
Drug	DiC8	PRKACA PRKACB KCNN4 PRKCI PRKCQ	1.30e-04	146	76	5	CID000001323
Drug	ML-9	ROCK2 PRKACA ROCK1 PRKCI AKT2	1.34e-04	147	76	5	CID000004217
Drug	butaprost	PRKACA PRKACB KCNN4 PRKCI	1.36e-04	78	76	4	CID005311035
Drug	barium	KCNJ6 KCNJ8 KCNN4 PRKCI PRKCQ	1.38e-04	148	76	5	CID000104810
Drug	GF109203X	ROCK2 SLC7A2 PRKACA PRKACB ROCK1 PRKCI PRKCQ	1.43e-04	341	76	7	CID000002396
Drug	fasudil	ROCK2 PRKACA PRKACB ROCK1 PRKCI	1.52e-04	151	76	5	CID000003547
Drug	GTP[S]	ROCK2 KCNJ6 KCNJ8 PRKACA PRKACB ROCK1 PRKCI PRKCQ PTK7	1.53e-04	591	76	9	CID000001764
Drug	brazilein	ROCK2 ROCK1	1.64e-04	6	76	2	CID006453902
Drug	levormeloxifene	ROCK2 ROCK1	1.64e-04	6	76	2	ctd:C108255
Drug	AC1L1CTF	ROCK2 ROCK1	1.64e-04	6	76	2	CID000002056
Drug	nM-1	ROCK2 KCNN4 ROCK1 PRKCI PTK7	1.72e-04	155	76	5	CID000445754
Drug	NSC611747	ROCK2 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI PTK7	1.74e-04	352	76	7	CID000002534
Drug	A61603	ROCK2 RPS6KA2 ROCK1	1.81e-04	33	76	3	CID004038180
Drug	PDBu	ROCK2 PRKACA PRKACB ROCK1 PRKCI PRKCQ	1.86e-04	249	76	6	CID000037783
Drug	W7 hydrochloride	ROCK2 PRKACA PRKACB KCNN4 ROCK1 PRKCI	1.90e-04	250	76	6	CID000005681
Drug	dihydrochloride	ROCK2 PRKACA PRKACB ROCK1 PRKCI	1.93e-04	159	76	5	CID000070978
Drug	ON 01910	TNK1 PRKCI AKT2 FGFR2 EPHA1	2.11e-04	162	76	5	ctd:C507134
Drug	6-BME	ROCK2 ROCK1	2.28e-04	7	76	2	CID005748218
Drug	AC1L2VEC	ROCK2 ROCK1	2.28e-04	7	76	2	CID000129320
Drug	1,3-diolein	PRKACA PRKACB PRKCI PRKCQ	2.36e-04	90	76	4	CID000033120
Drug	NSC618487	ROCK2 BMX KCNJ6 RPS6KA2 PRKACA PRKACB ROCK1 PRKCI PRKCQ FGFR2 ITK	2.58e-04	933	76	11	CID000005279
Drug	lavendustin A	PRKACA PRKACB PRKCI FGFR2 TEC	2.71e-04	171	76	5	CID000003894
Drug	EIPA	KCNN4 ROCK1 PRKCI PRKCQ	2.90e-04	95	76	4	CID000001795
Drug	12-deoxyphorbol 13-isobutyrate	ROCK2 ROCK1 PRKCI	3.00e-04	39	76	3	CID000107855
Drug	GGTI-297	ROCK2 ROCK1	3.04e-04	8	76	2	CID009956145
Drug	heptenoic acid	ROCK2 ROCK1	3.04e-04	8	76	2	CID000029373
Drug	N-palmitoyl-serine	ROCK2 ROCK1	3.04e-04	8	76	2	CID000085997
Drug	oxethazaine	ROCK2 ROCK1	3.04e-04	8	76	2	CID000004621
Drug	SC-46275	ROCK2 ROCK1	3.04e-04	8	76	2	CID005311427
Drug	Y-26763	ROCK2 ROCK1	3.04e-04	8	76	2	CID000121878
Drug	1d3q	PRKACA PRKACB PTK7	3.23e-04	40	76	3	CID000001635
Drug	glycitein	DPP9 PRKACA TNFAIP6 EPHA1	3.27e-04	98	76	4	ctd:C086566
Drug	OD-q	ROCK2 PRKACA PRKACB KCNN4 ROCK1	3.34e-04	179	76	5	CID000001456
Drug	Reidispongiolide C	ROCK2 NTRK2 ROCK1 AKT2 EPHA1 TXK	3.42e-04	279	76	6	CID005289285
Drug	antibiotic from Streptomyces	PRKACA PRKCI PRKCQ	3.74e-04	42	76	3	CID000005153
Drug	P6Chol	ROCK2 ROCK1	3.90e-04	9	76	2	CID000126085
Drug	fluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A	MAST4 RPS6KA2 SREBF2 FGFR2 EPHA1	3.98e-04	186	76	5	6996_UP
Drug	Ro 31-8830	ROCK2 PRKACA ROCK1 PRKCI	4.09e-04	104	76	4	CID000005084
Drug	Apigenin [520-36-5]; Down 200; 14.8uM; MCF7; HT_HG-U133A	ROCK2 OSBPL2 ROCK1 EPHA1 DNMT3B	4.18e-04	188	76	5	3257_DN
Drug	KT5720	ROCK2 PRKACA PRKACB ROCK1 PRKCI	4.29e-04	189	76	5	CID000003844
Drug	SC-560	ROCK2 FLII ROCK1	4.29e-04	44	76	3	CID004306515
Drug	AC1OAGFB	ROCK2 TRPM5 KCNJ6 KCNJ8 PRKACA ROCK1 PRKCI PRKCQ	4.30e-04	539	76	8	CID006857345
Drug	Go6976	SLC7A3 PRKACA PRKACB PRKCI PRKCQ	4.39e-04	190	76	5	CID000003501
Drug	FTI-277	ROCK2 NTRK2 ROCK1 AKT2	4.40e-04	106	76	4	CID003005531
Drug	20-HETE	ROCK2 ROCK1 PRKCI PRKCQ	4.40e-04	106	76	4	CID005283157
Drug	Potassium	KCNJ6 KCNJ8 KCNN4 NLRP3	4.40e-04	106	76	4	ctd:D011188
Drug	phosphine oxide	PRKACA PRKACB PRKCI PRKCQ	4.56e-04	107	76	4	CID000166931
Drug	AC1L1E8W	KCNJ6 PRKACA PRKACB KCNN4	4.56e-04	107	76	4	CID000002691
Drug	Dipyrone [5907-38-0]; Down 200; 12uM; MCF7; HT_HG-U133A	XYLT2 NTRK2 PRKACA SREBF2 FGFR2	4.61e-04	192	76	5	3929_DN
Drug	nifedipine	ROCK2 PRKACA PRKACB ROCK1 PRKCI SCD5 NLRP3	4.71e-04	415	76	7	CID000004485
Drug	A13108	KCNJ6 KCNJ8	4.86e-04	10	76	2	CID000062278
Drug	Ozagrel hydrochloride [78712-43-3]; Up 200; 15.2uM; HL60; HT_HG-U133A	FLII GALNT10 OSBPL2 SREBF2 EPHA1	4.94e-04	195	76	5	2942_UP
Drug	CP-690334-01 [459212-38-5]; Down 200; 1uM; MCF7; HT_HG-U133A	SLC7A2 SREBF2 SLC12A8 AKT2 EPHA1	4.94e-04	195	76	5	3909_DN
Drug	Atropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; MCF7; HT_HG-U133A	OSBPL2 NDUFAF7 PRKACA SLC12A8 GLB1L2	4.94e-04	195	76	5	2761_DN
Drug	Thiamphenicol [15318-45-3]; Down 200; 11.2uM; MCF7; HT_HG-U133A	TMEM120B MAST4 TM7SF3 SREBF2 KCNN4	4.94e-04	195	76	5	1704_DN
Drug	ST021200; Up 200; 10uM; PC3; HT_HG-U133A	XYLT2 TNK1 MAST4 SREBF2 EPHA1	4.94e-04	195	76	5	7559_UP
Drug	Gemfibrozil [25812-30-0]; Up 200; 16uM; MCF7; HT_HG-U133A	MAST4 SREBF2 KCNN4 SLC12A8 PRKCQ	5.06e-04	196	76	5	5488_UP
Disease	Metastatic melanoma	ROCK2 RPS6KA2 PRKCI ITK	1.11e-05	54	75	4	C0278883
Disease	Intrahepatic Cholangiocarcinoma	PRKACA PRKACB FGFR2	3.07e-05	24	75	3	C0345905
Disease	Extrahepatic Cholangiocarcinoma	PRKACA PRKACB FGFR2	3.07e-05	24	75	3	C3805278
Disease	FEV change measurement, response to zileuton	PRSS35 SLC7A2 LMBRD1	3.48e-05	25	75	3	EFO_0005921, EFO_0007676
Disease	tyrosine-protein kinase TEC measurement	TEC TEC	3.81e-05	4	75	2	EFO_0020830
Disease	Cholangiocarcinoma	PRKACA PRKACB FGFR2	3.93e-05	26	75	3	C0206698
Disease	non-alcoholic fatty liver disease (implicated_via_orthology)	SLC7A3 ZMPSTE24 NLRP3	1.06e-04	36	75	3	DOID:0080208 (implicated_via_orthology)
Disease	Adenocarcinoma of large intestine	RPS6KA2 AKT2 PRKCQ PTK7	1.07e-04	96	75	4	C1319315
Disease	high grade glioma (implicated_via_orthology)	PRKCI AKT2 FGFR2	1.94e-04	44	75	3	DOID:3070 (implicated_via_orthology)
Disease	ceramide measurement	NTRK2 PRKCQ TEC TEC TXK	3.37e-04	235	75	5	EFO_0010222
Disease	Vertigo	GALNTL6 MAST4 SLC12A8 PRKCQ	4.42e-04	139	75	4	HP_0002321
Disease	cystathionine measurement	TEC TEC	1.06e-03	19	75	2	EFO_0010474
Disease	Nystagmus	MAST4 KCNJ6	1.30e-03	21	75	2	HP_0000639
Disease	idiopathic pulmonary fibrosis (is_marker_for)	NTRK2 FGFR2	1.56e-03	23	75	2	DOID:0050156 (is_marker_for)
Disease	alcohol use disorder (implicated_via_orthology)	PRKACA PRKACB SREBF2 AKT2	1.56e-03	195	75	4	DOID:1574 (implicated_via_orthology)
Disease	lysophosphatidylcholine 18:0 measurement	TMTC1 KCNJ6	1.70e-03	24	75	2	EFO_0010359
Disease	endometriosis (is_marker_for)	FGFR2 DNMT3B	1.84e-03	25	75	2	DOID:289 (is_marker_for)
Disease	prostate carcinoma	GDF5 SLC7A3 MAST4 PTPRD PRKCI FGFR2 TNFAIP6 DNMT3B	1.90e-03	891	75	8	EFO_0001663
Disease	blood rubidium measurement	KCNJ6 TNFAIP6	1.99e-03	26	75	2	EFO_0021529
Disease	retinitis pigmentosa (implicated_via_orthology)	FGFR2 PRPF8	2.15e-03	27	75	2	DOID:10584 (implicated_via_orthology)
Disease	Mammary Carcinoma, Human	PTPRD SREBF2 AKT2 FGFR2 GALNT16 DNMT3B	2.20e-03	525	75	6	C4704874
Disease	Mammary Neoplasms, Human	PTPRD SREBF2 AKT2 FGFR2 GALNT16 DNMT3B	2.20e-03	525	75	6	C1257931
Disease	Mammary Neoplasms	PTPRD SREBF2 AKT2 FGFR2 GALNT16 DNMT3B	2.24e-03	527	75	6	C1458155
Disease	lysophosphatidylethanolamine 22:6 measurement	TMTC1 KCNJ6	2.31e-03	28	75	2	EFO_0010371
Disease	type 2 diabetes mellitus (implicated_via_orthology)	ZMPSTE24 PRKCI AKT2	2.45e-03	105	75	3	DOID:9352 (implicated_via_orthology)
Disease	Breast Carcinoma	PTPRD SREBF2 AKT2 FGFR2 GALNT16 DNMT3B	2.49e-03	538	75	6	C0678222

Protein segments in the cluster

Peptide	Gene	Start	Entry
MGLSGSDFPDEEWLW	BEST3	366	Q8N1M1
DYGRAVDWWGLGVVM	AKT2	326	P31751
TGDRGIMDEDGYFWW	ACSM6	451	Q6P461
ASDVWSFGIVMWEVL	EPHA1	806	P21709
SLELLFSDWGMEWAQ	NKAPP1	51	Q8N9T2
SGMRWVQWFGDGKFS	DNMT3B	256	Q9UBC3
WAFGILMWEVFSLGK	BMX	596	P51813
ADTWVRFSIWMAIGF	SLC7A2	581	P52569
IWGGENFELSFRVWM	GALNT16	316	Q8N428
TGGLAWWNDFMVLAC	RIC1	541	Q4ADV7
WFWGSIQMDARAGET	ECT2	336	Q9H8V3
VWSFGVLMWEIFTLG	FGFR2	686	P21802
FVGIWCWRFDEMTQT	MMP27	391	Q9H306
DWWALGVLIYEMAAG	PRKACA	221	P17612
GFSVDWWALGVLMFE	PRKCI	431	P41743
DWWSFGVLLYEMLIG	PRKCQ	561	Q04759
FWQGREASNMGWLTF	FLII	986	Q13045
LDGSGWEVFDIWKLF	GDF5	286	P43026
LFAIMWWLVAFAHGD	KCNJ8	86	Q15842
VLHAEMLWFGGCSWA	KCNN4	41	O15554
FFGMIWWLIAYIRGD	KCNJ6	106	P48051
VMAGGLFAVDRKWFW	GALNT10	316	Q86SR1
SMAGIRNIGIWFFWI	LMBRD1	381	Q9NUN5
VFTGNELAALFGWWM	PGM2L1	351	Q6PCE3
ISMACVGFFWLQGAW	KIR2DS3	6	Q14952
ALMFADGWQAGLGTW	TUBGCP5	961	Q96RT8
DETWILFLPMEWGDS	IL1RL2	76	Q9HB29
MAVDVEFGVAGWWEA	RESP18	1	Q5W5W9
DWWALGVLIYEMAAG	PRKACB	221	P22694
GWTRDGKYAWAMFLD	DPP9	356	Q86TI2
GWDDSFWKMIGLEDF	FGGY	201	Q96C11
WWAMGIILYEFLVGC	MAST4	766	O15021
GWNFMLEDSTFWIFG	GLB1L2	51	Q8IW92
DNLGFPVSDWLFSMW	ZMPSTE24	441	O75844
LFMWEPVLFGTWDGV	SLC12A8	31	A0AV02
TWARFGVWMLIGFAI	SLC7A3	566	Q8WY07
SLPETFGDFWRMIWE	PTPRD	1431	P23468
VWSFGVLMWEVFSEG	ITK	541	Q08881
FNGEEKAWAMAVWIF	NLRP3	61	Q96P20
VMAGGLFAVDRKWFW	GALNTL6	311	Q49A17
WWAYEIGSFLMGLLS	SLC47A2	306	Q86VL8
TVEGFQSWMWRGLTF	TMEM120B	256	A0PK00
VEGFQSWMWRGLTFL	TMEM120A	261	Q9BXJ8
SDVWSFGVLMWEVFT	TEC	546	P42680
IFGELLGIWFISEWM	NDUFAF7	96	Q7L592
WFIDFMCWLGLATDR	SCD5	296	Q86SK9
TFLEDGIRMWFQWSE	SURF4	36	O15260
YMHLVWGSWGLGFLD	OR8S1	141	Q8NH09
FMIYGKWTECLWGID	OSBPL2	296	Q9H1P3
WEGSALTGAWAMEDF	SLX4	531	Q8IY92
GYSFEVDWWSVGVMA	STK32C	271	Q86UX6
CWLHLDQGFMWSFLG	ADGRE3	496	Q9BY15
TAAIAGCWWGVMYGF	ADPRH	306	P54922
MWVFGYGSLIWKVDF	CHAC2	1	Q8WUX2
AMARLWGFCWLVVGF	NTRK2	11	Q16620
AAGWRVWLFFMRGIT	PRPF8	631	Q6P2Q9
LGFCISWFLVWMDGV	TMEM240	96	Q5SV17
SWFLVWMDGVLHCAV	TMEM240	101	Q5SV17
LWEDTQGWGFKDGIF	TNFAIP6	11	P98066
WGMDAISATLTFLWE	UNC80	1946	Q8N2C7
WGIFTNDFWGKGMAE	TMTC1	71	Q8IUR5
AFLTRIWWGDMAAGT	TRPM5	631	Q9NZQ8
DGGWGWMIVIHFFLV	SLC16A4	16	O15374
FTPGWTLIDGSEMEW	PRSS35	11	Q8N3Z0
VLSFESGSGGWFDWM	SREBF2	521	Q12772
GILFFTGWWIMIDAA	TMEM50B	31	P56557
DWWSVGVFLYEMLVG	ROCK2	276	O75116
DFILAVLWAVVWFMG	SYNGR4	106	O95473
WWSVGVFLYEMLVGD	ROCK1	261	Q13464
KSDVWSFGVLMWEVF	TXK	446	P42681
VTLWEMFSGGEEPWA	TNK1	311	Q13470
WFSIGFDWTWMLLFG	WLS	286	Q5T9L3
FDWTWMLLFGDIRQG	WLS	291	Q5T9L3
KSDVWAFGVLMWEVF	PTK7	986	Q13308
MRDLLEVPGWAWDFF	XYLT2	311	Q9H1B5
PFGQWWASVGMDDFL	TLE6	511	Q9H808
SVGGMFLVAVWWRFG	TM7SF3	356	Q9NS93
DWWSFGVLMFEMLTG	RPS6KA2	241	Q15349