Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	TSPOAP1 RIMBP3 RIMBP3C RIMBP3B	1.18e-08	5	141	4	GO:0030156
GeneOntologyMolecularFunction	cytoskeletal protein binding	DLG5 SYNM MYO1H APC2 DNM1L AIF1L CCDC88B ADCY8 SPTBN5 CCDC88C DST DLC1 USH1G MACO1 SYNE2 KIF19 PLEC ARHGEF2 CORO7 MTUS2 NLRP5	2.98e-05	1099	141	21	GO:0008092
GeneOntologyMolecularFunction	microtubule binding	APC2 DNM1L CCDC88B CCDC88C DST MACO1 KIF19 ARHGEF2 MTUS2	3.47e-04	308	141	9	GO:0008017
GeneOntologyBiologicalProcess	supramolecular fiber organization	EPPK1 DSP CARMIL3 KRT82 MYO1H PPFIA1 APC2 AIF1L CCDC88B SPTBN5 RHPN1 CCDC88C DLC1 PDE4DIP KIF19 PLEC ARHGEF2 CORO7 NLRP5	2.34e-05	957	139	19	GO:0097435
GeneOntologyBiologicalProcess	actin filament-based process	CDC42BPG DSP CARMIL3 MYO1H PPFIA1 S1PR2 AIF1L BCR SH2B2 SPTBN5 RHPN1 CCDC88C DLC1 SYNE2 PLEC ARHGEF2 CORO7 NLRP5	4.23e-05	912	139	18	GO:0030029
GeneOntologyBiologicalProcess	intermediate filament cytoskeleton organization	EPPK1 SYNM DSP KRT82 DST PLEC	5.63e-05	99	139	6	GO:0045104
GeneOntologyBiologicalProcess	intermediate filament-based process	EPPK1 SYNM DSP KRT82 DST PLEC	5.96e-05	100	139	6	GO:0045103
GeneOntologyBiologicalProcess	regulation of cellular response to osmotic stress	LETM1 EFHD1 ARHGEF2	8.15e-05	13	139	3	GO:0106049
GeneOntologyBiologicalProcess	neuromuscular synaptic transmission	TSPOAP1 RIMBP3 RIMBP3C RIMBP3B	9.84e-05	36	139	4	GO:0007274
GeneOntologyBiologicalProcess	negative regulation of organelle organization	PPFIA1 APC2 BAZ1B DNM1L SPDL1 SPTBN5 RHPN1 CCDC88C DLC1 ARHGEF2 ESPL1	1.36e-04	421	139	11	GO:0010639
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	EPPK1 SYNM DSP KRT82 APC2 AKNA DNM1L AIF1L SH2B2 DST DLC1 PDE4DIP KIF19 PLEC LZTS2 ARHGEF2 CFAP53 MTUS2 CNP PCNT	2.66e-06	899	141	20	GO:0099513
GeneOntologyCellularComponent	supramolecular fiber	EPPK1 SYNM DSP KRT82 KLHL40 APC2 AKNA DNM1L AIF1L SH2B2 DST DLC1 SYNE2 PDE4DIP KIF19 PLEC LZTS2 ARHGEF2 CFAP53 MTUS2 CNP PCNT	1.34e-05	1179	141	22	GO:0099512
GeneOntologyCellularComponent	microtubule organizing center	CDC42BPG DLG5 CCDC22 AKNA RASSF10 CCDC88B STX1B SPDL1 CCDC88C PPP4C GLG1 USH1G CROCC2 PDE4DIP LZTS2 ESPL1 CFAP53 MTUS2 PCNT	1.37e-05	919	141	19	GO:0005815
GeneOntologyCellularComponent	supramolecular polymer	EPPK1 SYNM DSP KRT82 KLHL40 APC2 AKNA DNM1L AIF1L SH2B2 DST DLC1 SYNE2 PDE4DIP KIF19 PLEC LZTS2 ARHGEF2 CFAP53 MTUS2 CNP PCNT	1.49e-05	1187	141	22	GO:0099081
GeneOntologyCellularComponent	centrosome	CDC42BPG CCDC22 AKNA RASSF10 CCDC88B STX1B SPDL1 CCDC88C PPP4C USH1G CROCC2 PDE4DIP LZTS2 ESPL1 CFAP53 MTUS2 PCNT	1.76e-05	770	141	17	GO:0005813
GeneOntologyCellularComponent	manchette	RIMBP3 RIMBP3C RIMBP3B CFAP53	3.58e-05	28	141	4	GO:0002177
GeneOntologyCellularComponent	hemidesmosome	EPPK1 DST PLEC	4.76e-05	11	141	3	GO:0030056
GeneOntologyCellularComponent	microtubule	APC2 AKNA DNM1L DST PDE4DIP KIF19 LZTS2 ARHGEF2 CFAP53 MTUS2 CNP PCNT	2.70e-04	533	141	12	GO:0005874
GeneOntologyCellularComponent	actin cytoskeleton	MYO1H APC2 TMEM63B AIF1L SH2B2 ADCY8 SPTBN5 DST DLC1 USH1G ARHGEF2 CCDC102A	5.41e-04	576	141	12	GO:0015629
GeneOntologyCellularComponent	cell leading edge	CDC42BPG CARMIL3 APC2 AIF1L SH2B2 DST DLC1 SYNE2 NGFR RIPOR1 ARHGEF2	5.91e-04	500	141	11	GO:0031252
GeneOntologyCellularComponent	protein phosphatase 4 complex	PPP4R1 PPP4C	6.66e-04	6	141	2	GO:0030289
MousePheno	increased cell migration	EPPK1 S1PR2 DLC1 INAVA CORO7	5.96e-08	14	113	5	MP:0011804
Domain	-	EPPK1 DSP DST PLEC	3.76e-08	6	134	4	3.90.1290.10
Domain	Plectin	EPPK1 DSP DST PLEC	8.72e-08	7	134	4	PF00681
Domain	Plectin_repeat	EPPK1 DSP DST PLEC	8.72e-08	7	134	4	IPR001101
Domain	PLEC	EPPK1 DSP DST PLEC	8.72e-08	7	134	4	SM00250
Domain	Spectrin_repeat	DSP SPTBN5 DST SYNE2 PLEC	1.82e-06	29	134	5	IPR002017
Domain	SPEC	DSP SPTBN5 DST SYNE2 PLEC	3.04e-06	32	134	5	SM00150
Domain	Spectrin/alpha-actinin	DSP SPTBN5 DST SYNE2 PLEC	3.04e-06	32	134	5	IPR018159
Domain	ACTININ_2	SPTBN5 DST SYNE2 PLEC	2.02e-05	23	134	4	PS00020
Domain	ACTININ_1	SPTBN5 DST SYNE2 PLEC	2.02e-05	23	134	4	PS00019
Domain	Actinin_actin-bd_CS	SPTBN5 DST SYNE2 PLEC	2.02e-05	23	134	4	IPR001589
Domain	SAM	PPFIA1 PPFIA3 DLC1 USH1G ANKS3	4.29e-04	88	134	5	SM00454
Domain	Spectrin	SPTBN5 DST SYNE2	5.76e-04	23	134	3	PF00435
Domain	SAM_DOMAIN	PPFIA1 PPFIA3 DLC1 USH1G ANKS3	6.10e-04	95	134	5	PS50105
Domain	SAM	PPFIA1 PPFIA3 DLC1 USH1G ANKS3	6.70e-04	97	134	5	IPR001660
Domain	HR1_rho-bd	PPFIA1 RHPN1 ATP6V0A4	7.40e-04	25	134	3	IPR011072
Domain	HOOK	CCDC88B CCDC88C	7.52e-04	6	134	2	PF05622
Domain	Hook-related_fam	CCDC88B CCDC88C	7.52e-04	6	134	2	IPR008636
Domain	Liprin	PPFIA1 PPFIA3	7.52e-04	6	134	2	IPR029515
Domain	CH	SPTBN5 DST SYNE2 PLEC	1.22e-03	65	134	4	SM00033
Domain	SAM_1	PPFIA1 PPFIA3 USH1G ANKS3	1.45e-03	68	134	4	PF00536
Domain	SAM/pointed	PPFIA1 PPFIA3 DLC1 USH1G ANKS3	1.56e-03	117	134	5	IPR013761
Domain	CH	SPTBN5 DST SYNE2 PLEC	1.61e-03	70	134	4	PF00307
Domain	-	SPTBN5 DST SYNE2 PLEC	1.70e-03	71	134	4	1.10.418.10
Domain	CH	SPTBN5 DST SYNE2 PLEC	1.88e-03	73	134	4	PS50021
Domain	CH-domain	SPTBN5 DST SYNE2 PLEC	2.08e-03	75	134	4	IPR001715
Domain	SH3_9	TSPOAP1 RIMBP3 RIMBP3C RIMBP3B	2.40e-03	78	134	4	PF14604
Domain	ARM-like	PPP4R1 APC2 HEATR5A ARVCF NCAPD2 RIPOR1 USP35	3.38e-03	270	134	7	IPR011989
Domain	SH3_2	TSPOAP1 RIMBP3 RIMBP3C RIMBP3B	3.42e-03	86	134	4	PF07653
Domain	SH3_2	TSPOAP1 RIMBP3 RIMBP3C RIMBP3B	3.42e-03	86	134	4	IPR011511
Domain	SAM_2	PPFIA1 PPFIA3 DLC1	3.61e-03	43	134	3	PF07647
Domain	-	DLG5 CARD10 NGFR NLRP5	4.52e-03	93	134	4	1.10.533.10
Domain	SH3	DLG5 TSPOAP1 RIMBP3 DST RIMBP3C RIMBP3B	4.70e-03	216	134	6	PS50002
Domain	SH3_domain	DLG5 TSPOAP1 RIMBP3 DST RIMBP3C RIMBP3B	5.14e-03	220	134	6	IPR001452
Domain	-	PPP4R1 APC2 HEATR5A ARVCF NCAPD2 RIPOR1	5.36e-03	222	134	6	1.25.10.10
Domain	DEATH-like_dom	DLG5 CARD10 NGFR NLRP5	5.64e-03	99	134	4	IPR011029
Domain	-	PPFIA1 PPFIA3 USH1G ANKS3	7.16e-03	106	134	4	1.10.150.50
Pathway	REACTOME_RHO_GTPASE_CYCLE	DLG5 DSP BCR LETM1 SHKBP1 RHPN1 DST DLC1 ARHGEF39 MACO1 ARHGEF2	1.47e-04	450	91	11	M27078
Pathway	REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE	TSPOAP1 PPFIA1 PPFIA3	1.66e-04	17	91	3	M93
Pathway	REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE	TSPOAP1 PPFIA1 PPFIA3	1.66e-04	17	91	3	MM14907
Pathway	REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE	TSPOAP1 PPFIA1 PPFIA3	1.98e-04	18	91	3	M13015
Pathway	REACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE	TSPOAP1 PPFIA1 PPFIA3	1.98e-04	18	91	3	MM14702
Pathway	REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE	TSPOAP1 PPFIA1 PPFIA3	1.98e-04	18	91	3	MM14703
Pathway	REACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE	TSPOAP1 PPFIA1 PPFIA3	1.98e-04	18	91	3	M27043
Pathway	REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE	TSPOAP1 PPFIA1 PPFIA3	4.20e-04	23	91	3	MM14852
Pathway	REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE	TSPOAP1 PPFIA1 PPFIA3	4.20e-04	23	91	3	M12627
Pathway	REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE	TSPOAP1 PPFIA1 PPFIA3	4.77e-04	24	91	3	MM14834
Pathway	REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE	TSPOAP1 PPFIA1 PPFIA3	4.77e-04	24	91	3	M630
Pathway	REACTOME_RHO_GTPASE_CYCLE	DLG5 DSP BCR LETM1 RHPN1 DST DLC1 ARHGEF39 MACO1 ARHGEF2	5.23e-04	439	91	10	MM15595
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EPPK1 SZT2 FOSL2 POLRMT AKNA PFAS CARD10 RNF40 COMTD1 BCR FAAP100 SH2B2 RHPN1 CCDC88C FAM20C DST ARVCF IL17RE NCAPD2 RIPOR1 PLEC ARHGEF2 ESPL1 PCNT	2.29e-11	1105	142	24	35748872
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	TSPOAP1 RIMBP3 RIMBP3C RIMBP3B	1.33e-09	5	142	4	17855024
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	DLG5 KRT82 RNF213 SPTBN5 DST SYNE2 PLEC MUC5AC PCNT	8.36e-08	187	142	9	26460568
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	PPFIA1 APC2 DNM1L PPFIA3 BCR CCDC177 LETM1 EPM2AIP1 CCDC88C DST ARVCF SYNE2 PDE4DIP DCHS1 SAFB2 ARHGEF2 CNP PCNT	8.71e-08	963	142	18	28671696
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	CCDC22 PPFIA1 VPS33A BCR SH2B2 MACO1 SYNE2 LZTS2 ARHGEF2 ALDH9A1	9.24e-08	251	142	10	29778605
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	2.66e-07	4	142	3	19091768
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PPP4R1 CCDC22 DSP PPFIA1 PSMB2 RNF213 PFAS PPFIA3 LETM1 SHKBP1 ESYT2 PPP4C ARVCF MACO1 SYNE2 LZTS2 ARHGEF2 PCNT	3.06e-07	1049	142	18	27880917
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	EPPK1 DSP BAZ1B PFAS CARD10 RNF40 PPFIA3 BCR LETM1 SYNE2 DCHS1 SAFB2 RIPOR1 TXLNG	2.80e-06	754	142	14	35906200
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	DLG5 FOSL2 PPFIA1 PSMB2 RPP38 POLRMT BAZ1B AIF1L SIRT7 COMTD1 SHKBP1 ESYT2 DST EFHD1 GLG1 MACO1 NCAPD2 LZTS2 ARHGEF2 CNP	3.15e-06	1497	142	20	31527615
Pubmed	A conserved acetylation switch enables pharmacological control of tubby-like protein stability.	PPFIA1 PPFIA3 BCR GLG1 PDE4DIP TONSL ARHGEF2 RNF138	4.05e-06	223	142	8	33187986
Pubmed	Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.	DSP DST PLEC	5.50e-06	9	142	3	12482924
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	PPP4R1 DLG5 DSP BAZ1B PFAS RNF40 BCR RIMBP3 MACO1 TONSL LZTS2 PCNT	5.78e-06	588	142	12	38580884
Pubmed	Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.	RNF40 SPDL1 CCDC88C DST PDE4DIP MTUS2	6.63e-06	111	142	6	22558309
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	EPPK1 FOSL2 BAZ1B LETM1 DST ARHGEF39 PLEC ARHGEF2 SEC14L5	9.70e-06	332	142	9	37433992
Pubmed	Interaction of the bullous pemphigoid antigen 1 (BP230) and desmoplakin with intermediate filaments is mediated by distinct sequences within their COOH terminus.	DSP DST PLEC	1.07e-05	11	142	3	12802069
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	PPFIA1 PSMB2 POLRMT DNM1L PFAS BCR FAAP100 SHKBP1 ESYT2 MACO1 LZTS2 ALDH9A1 CORO7 ESPL1 CNP	1.15e-05	974	142	15	28675297
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DLG5 SZT2 AKNA RNF40 BCR DST NCAPD2 LZTS2 HPS5 ESPL1 ANKS3	1.21e-05	529	142	11	14621295
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DLG5 DSP PPFIA1 DNM1L BCR SHKBP1 CCDC88C ESYT2 DST DLC1 SYNE2 PLEC ARHGEF2 CCDC102A	1.26e-05	861	142	14	36931259
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PPP4R1 CDC42BPG POLRMT PFAS BCR LETM1 DST ARVCF TONSL ARHGEF2 HPS5 RUBCN	1.57e-05	650	142	12	38777146
Pubmed	Plakins in development and disease.	EPPK1 PLEC	1.66e-05	2	142	2	17499243
Pubmed	Direct interaction of the Usher syndrome 1G protein SANS and myomegalin in the retina.	USH1G PDE4DIP	1.66e-05	2	142	2	21767579
Pubmed	Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease.	DNM1L CNP	1.66e-05	2	142	2	33277246
Pubmed	Functional analyses of Pericentrin and Syne-2 interaction in ciliogenesis.	SYNE2 PCNT	1.66e-05	2	142	2	30054381
Pubmed	A PP4 holoenzyme balances physiological and oncogenic nuclear factor-kappa B signaling in T lymphocytes.	PPP4R1 PPP4C	1.66e-05	2	142	2	23084358
Pubmed	Kendrin is a novel substrate for separase involved in the licensing of centriole duplication.	ESPL1 PCNT	1.66e-05	2	142	2	22542101
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3 RIMBP3C RIMBP3B	2.35e-05	14	142	3	17662146
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	DLG5 PPFIA1 PFAS BCR ESYT2 DST LZTS2	2.56e-05	209	142	7	36779422
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	EPPK1 DSP BAZ1B NCAPD2 PLEC ARHGEF2 PCNT	2.64e-05	210	142	7	16565220
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	PPFIA3 ESYT2 DST SYNE2 HPS5 UNC80 PCNT	4.10e-05	225	142	7	12168954
Pubmed	Plakins: a family of versatile cytolinker proteins.	EPPK1 PLEC	4.95e-05	3	142	2	11854008
Pubmed	Deregulated expression of Cdc6 as BCR/ABL-dependent survival factor in chronic myeloid leukemia cells.	BCR CDC6	4.95e-05	3	142	2	28639894
Pubmed	BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin.	DST PLEC	4.95e-05	3	142	2	19932097
Pubmed	CCDC88B interacts with RASAL3 and ARHGEF2 and regulates dendritic cell function in neuroinflammation and colitis.	CCDC88B ARHGEF2	4.95e-05	3	142	2	38200184
Pubmed	Clonal Evolution and Blast Crisis Correlate with Enhanced Proteolytic Activity of Separase in BCR-ABL b3a2 Fusion Type CML under Imatinib Therapy.	BCR ESPL1	4.95e-05	3	142	2	26087013
Pubmed	Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication.	OAS1 ALDH9A1	4.95e-05	3	142	2	15893726
Pubmed	AMBRA1 promotes intestinal inflammation by antagonizing PP4R1/PP4c mediated IKK dephosphorylation in an autophagy-independent manner.	PPP4R1 PPP4C	4.95e-05	3	142	2	38424148
Pubmed	Leucine Carboxyl Methyltransferase 1 (LCMT-1) Methylates Protein Phosphatase 4 (PP4) and Protein Phosphatase 6 (PP6) and Differentially Regulates the Stable Formation of Different PP4 Holoenzymes.	PPP4R1 PPP4C	4.95e-05	3	142	2	27507813
Pubmed	Transcriptional regulation of agouti-related protein (Agrp) in transgenic mice.	AGRP RIPOR1	4.95e-05	3	142	2	15345681
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	CCDC22 PPFIA1 RNF213 RNF40 AIF1L BCR SPDL1 MACO1 ARHGEF2 ALDH9A1 CORO7 ESPL1	5.04e-05	733	142	12	34672954
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	DSP PPFIA1 POLRMT RNF40 BCR SPDL1 DST PLEC PCNT	5.87e-05	418	142	9	34709266
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	DLG5 EID2 POLRMT PPP4C CDC6 ESPL1 TXLNG	6.49e-05	242	142	7	34011540
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	EPPK1 DSP POLRMT BAZ1B PFAS SIRT7 DST SYNE2 NCAPD2 PLEC PCNT	8.14e-05	653	142	11	22586326
Pubmed	Identification of EFHD1 as a novel Ca(2+) sensor for mitoflash activation.	LETM1 EFHD1	9.88e-05	4	142	2	26975899
Pubmed	Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase.	CDC6 ESPL1	9.88e-05	4	142	2	21041660
Pubmed	The p75 neurotrophin receptor in AgRP neurons is necessary for homeostatic feeding and food anticipation.	AGRP NGFR	9.88e-05	4	142	2	31995032
Pubmed	Histone deacetylase 3 (HDAC3) activity is regulated by interaction with protein serine/threonine phosphatase 4.	PPP4R1 PPP4C	9.88e-05	4	142	2	15805470
Pubmed	Role of binding of plectin to the integrin beta4 subunit in the assembly of hemidesmosomes.	DST PLEC	9.88e-05	4	142	2	14668477
Pubmed	Drp1 is required for AgRP neuronal activity and feeding.	DNM1L AGRP	9.88e-05	4	142	2	33689681
Pubmed	Purification and identification of a novel subunit of protein serine/threonine phosphatase 4.	PPP4R1 PPP4C	9.88e-05	4	142	2	10026142
Pubmed	Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.	CCDC22 VPS33A POLRMT DNM1L PFAS BCR LETM1 DST PPP4C	1.10e-04	454	142	9	33226137
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	DLG5 SYNM DSP ERFE LZTS2 CCDC102A	1.14e-04	184	142	6	32908313
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	DLG5 SYNM PPFIA1 PSMB2 POLRMT BAZ1B PFAS LETM1 ESYT2 GLG1 MACO1 SYNE2 LZTS2 ALDH9A1 ESPL1 TXLNG PCNT	1.26e-04	1487	142	17	33957083
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	DNM1L PFAS CARD10 LETM1 EPM2AIP1 ESYT2 CROCC2 PDE4DIP RIMBP3C LZTS2 NAIF1	1.30e-04	689	142	11	36543142
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	CCDC22 DSP PSMB2 RPP38 POLRMT BAZ1B PFAS DST ARVCF NCAPD2 SAFB2 PLEC ARHGEF2 ALDH9A1 CORO7 CNP	1.37e-04	1353	142	16	29467282
Pubmed	NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte-to-Embryo Transition.	DNM1L LETM1 NLRP5	1.43e-04	25	142	3	37493331
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	EPPK1 DSP PPFIA1 VPS33A DNM1L CARD10 NCAPD2 PLEC ARHGEF2 PCNT	1.47e-04	582	142	10	20467437
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	DSP ARHGEF39 GLG1 SYNE2 SAFB2 PLEC PCNT	1.50e-04	277	142	7	30745168
Pubmed	Protein phosphatase 4 catalytic subunit regulates Cdk1 activity and microtubule organization via NDEL1 dephosphorylation.	PPP4R1 PPP4C	1.64e-04	5	142	2	18347064
Pubmed	Multidrug resistance decreases with mutations of melanosomal regulatory genes.	VPS33A TYR	1.64e-04	5	142	2	19155314
Pubmed	The mouse and human Liprin-alpha family of scaffolding proteins: genomic organization, expression profiling and regulation by alternative splicing.	PPFIA1 PPFIA3	1.64e-04	5	142	2	19013515
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	DLG5 CCDC22 DSP BCR RIMBP3 CCDC88C ESYT2 MACO1 PLEC ARHGEF2 TXLNG PCNT	2.08e-04	853	142	12	28718761
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	EPPK1 SZT2 RNF213 DNM1L CCDC88C NLRP5	2.22e-04	208	142	6	33230847
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	EPPK1 RNF40 AIF1L LETM1 GLG1 PDE4DIP PLEC LZTS2 RBM41	2.36e-04	503	142	9	36217030
Pubmed	Tax1-binding protein 1 is expressed in the retina and interacts with the GABA(C) receptor rho1 subunit.	DNM1L BCR	2.46e-04	6	142	2	16999686
Pubmed	Analyses of the spatiotemporal expression and subcellular localization of liprin-α proteins.	PPFIA1 PPFIA3	2.46e-04	6	142	2	21618221
Pubmed	Epiplakin attenuates experimental mouse liver injury by chaperoning keratin reorganization.	EPPK1 DSP	2.46e-04	6	142	2	25617501
Pubmed	TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.	SYNE2 PLEC	2.46e-04	6	142	2	18827015
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	DSP PPFIA1 DNM1L PPFIA3 BCR CCDC177 LETM1 STX1B DST ARVCF PDE4DIP PLEC ARHGEF2 CORO7 MTUS2 CNP	2.57e-04	1431	142	16	37142655
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	DSP RNF213 SH2B2 SPTBN5 GLG1 PLEC	2.58e-04	214	142	6	22199357
Pubmed	The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome.	DST PLEC	3.43e-04	7	142	2	10637308
Pubmed	Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.	PPFIA3 BCR PLEC ARHGEF2 CNP	3.55e-04	147	142	5	16959763
Pubmed	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	BAZ1B MACO1 ABCG8	3.63e-04	34	142	3	19060911
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	DSP BAZ1B RNF40 DST SYNE2 HDAC10 ESPL1	3.74e-04	322	142	7	26514267
Pubmed	Network organization of the human autophagy system.	VPS33A POLRMT PFAS ESYT2 GLG1 SAFB2 ALDH9A1 RUBCN	4.52e-04	437	142	8	20562859
Pubmed	Bridging expressed sequence alignments through targeted cDNA sequencing.	SZT2 CARMIL3	4.56e-04	8	142	2	15028280
Pubmed	Evolutionary and molecular facts link the WWC protein family to Hippo signaling.	WWC3 DLC1	4.56e-04	8	142	2	24682284
Pubmed	A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication.	PPP4R1 PPP4C	4.56e-04	8	142	2	18614045
Pubmed	Epidermolysis Bullosa Simplex	DST PLEC	4.56e-04	8	142	2	20301543
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	SZT2 TSPOAP1 DSP CARMIL3 PPFIA1 RNF213 PDE4DIP ARHGEF2 UNC80	4.63e-04	552	142	9	10737800
Pubmed	Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.	SYNM RASSF10 ADCY8 FAM20C ANKS3	4.66e-04	156	142	5	22008794
Pubmed	Mutation of ARHGAP9 in patients with coronary spastic angina.	BCR DLC1 ARHGEF2	5.06e-04	38	142	3	19911011
Pubmed	Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins.	PPFIA1 PPFIA3	5.85e-04	9	142	2	12923177
Pubmed	Plakin proteins are coordinately cleaved during apoptosis but preferentially through the action of different caspases.	DSP PLEC	5.85e-04	9	142	2	15500642
Pubmed	Molecular mechanisms governing Pcdh-gamma gene expression: evidence for a multiple promoter and cis-alternative splicing model.	PCDHA5 PCDHA4	5.85e-04	9	142	2	12154121
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	DLG5 EPPK1 SYNM DSP SPDL1 PLEC	6.66e-04	256	142	6	33397691
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	P3H3 PPFIA1 RPP38 POLRMT L1TD1 BAZ1B RNF213 CRACR2B PPFIA3 BCR LZTS2 ANKS3 UNC80	6.83e-04	1116	142	13	31753913
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	SYNM EPM2AIP1 DST PLEC CORO7 TXLNG PCNT	7.23e-04	360	142	7	33111431
Pubmed	GemC1 controls multiciliogenesis in the airway epithelium.	MUC5AC PCNT	7.29e-04	10	142	2	26882546
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	CDC42BPG EPPK1 DSP PSMB2 RNF213 TONSL	7.82e-04	264	142	6	32814769
Pubmed	Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.	SYNE2 DCHS1 LZTS2 PCNT	8.00e-04	101	142	4	26949739
Pubmed	UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.	CCDC22 PFAS SPDL1 NCAPD2 ALDH9A1 TXLNG	8.29e-04	267	142	6	33417871
Pubmed	Centrosome-related genes, genetic variation, and risk of breast cancer.	NCAPD2 LZTS2 ESPL1 PCNT	8.30e-04	102	142	4	20508983
Pubmed	Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	TSPOAP1 RNF40 PPFIA3 ARHGEF2	8.30e-04	102	142	4	9734811
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	POLRMT RNF213 PFAS SHKBP1 GLG1 CDC6 MTUS2 CNP RNF138	8.77e-04	604	142	9	38803224
Pubmed	Two new cataract loci, Ccw and To3, and further mapping of the Npp and Opj cataracts in the mouse.	VPS33A TYR	8.89e-04	11	142	2	8812411
Pubmed	USP9X-mediated deubiquitination of B-cell CLL/lymphoma 9 potentiates Wnt signaling and promotes breast carcinogenesis.	EPPK1 PLEC	8.89e-04	11	142	2	31073027
Pubmed	The centrosome protein AKNA regulates neurogenesis via microtubule organization.	AKNA PCNT	8.89e-04	11	142	2	30787442
Pubmed	Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex.	PCDHA5 PCDHA4	8.89e-04	11	142	2	9655502
Pubmed	Molecular and functional architecture of striatal dopamine release sites.	TSPOAP1 PPFIA3	8.89e-04	11	142	2	34767769
Pubmed	The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes.	DST PLEC	8.89e-04	11	142	2	10811835
Interaction	TOP3B interactions	EPPK1 SZT2 FOSL2 POLRMT AKNA PFAS CARD10 RNF40 COMTD1 BCR FAAP100 SH2B2 RHPN1 CCDC88C FAM20C DST ARVCF IL17RE EFHD1 NCAPD2 SAFB2 RIPOR1 PLEC ARHGEF2 ESPL1 TXLNG PCNT	2.79e-06	1470	140	27	int:TOP3B
Interaction	KRT27 interactions	CCDC22 EPPK1 KRT82 L1TD1 RUNX1T1 CCDC88B SPDL1 TXLNG RBM41	1.21e-05	202	140	9	int:KRT27
Interaction	CEP135 interactions	DLG5 CCDC22 SYNM BCR CCDC88C SPATA2L MACO1 LZTS2 TXLNG PCNT	2.09e-05	272	140	10	int:CEP135
Interaction	SH2D4A interactions	LDOC1 CCDC88B PDE4DIP LZTS2 ALDH9A1 CFAP53 MTUS2	2.71e-05	125	140	7	int:SH2D4A
Interaction	CCDC6 interactions	PPP4R1 PFAS BCR RIMBP3 PPP4C MACO1 PDE4DIP LZTS2 MTUS2 CCDC102A	3.21e-05	286	140	10	int:CCDC6
Interaction	MAPRE3 interactions	DLG5 APC2 BCR DST MACO1 PDE4DIP KIF19 ARHGEF2 PCNT	3.37e-05	230	140	9	int:MAPRE3
Cytoband	22q11.21	RIMBP3 ARVCF RIMBP3C RIMBP3B CCDC188	2.60e-05	111	142	5	22q11.21
Cytoband	8q24.3	IQANK1 EPPK1 RHPN1 TONSL	4.35e-04	113	142	4	8q24.3
Cytoband	Ensembl 112 genes in cytogenetic band chr8q24	IQANK1 EPPK1 ADCY8 RHPN1 TONSL PLEC	8.68e-04	355	142	6	chr8q24
Cytoband	19p13.3	APC2 POLRMT R3HDM4 SAFB2 ANKRD24	8.87e-04	237	142	5	19p13.3
GeneFamily	EF-hand domain containing\|Plakins	EPPK1 DSP DST PLEC	2.71e-08	8	82	4	939
GeneFamily	Sterile alpha motif domain containing	PPFIA1 PPFIA3 USH1G ANKS3	6.86e-04	88	82	4	760
ToppCell	NS-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DSP CARD10 RUNX1T1 DST EFHD1 ATP6V0A4 NGFR	1.77e-06	179	142	7	65a96bee7bc28f5bfc20f0fd92bcc0ab2eb5e06c
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Deuterosomal\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MYO1H CROCC2 KIF19 CFAP74 CFAP53 CCDC188 CFAP99	1.98e-06	182	142	7	000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCell	droplet-Heart-nan-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAAP100 RHPN1 ARVCF EFHD1 KIF19 NGFR CNP	2.55e-06	189	142	7	0493f7b79127c207fd7ade778ef4810500495d7e
ToppCell	healthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SYNM AKNA RNF213 BCR CCDC88C SYNE2 KIF19	3.24e-06	196	142	7	af00c31612e4fe068e5fccae05368edba46bbd20
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SYNM AIF1L DST EFHD1 NGFR CNP SEC14L5	3.35e-06	197	142	7	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_B0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TRIM58 STX1B TONSL USP35 CFAP53 RUFY4	1.06e-05	155	142	6	a16e3a72badafa78a3efc4f4ab62396f0ce99d1e
ToppCell	VE-Treg-naive_CD4\|VE / Condition, Cell_class and T cell subcluster	EFHD1 SYNE2 CCDC154 PDE4DIP RIMBP3C INAVA	1.09e-05	156	142	6	6501baf73616e702946de9fb13d267e30a68888b
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CRACR2B PPFIA3 CCDC88B CXorf65 MSS51 RUBCN	1.26e-05	160	142	6	bb1bb3673059768c0ea0160d29fff127f3a4ecb4
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CRACR2B PPFIA3 CCDC88B CXorf65 MSS51 RUBCN	1.26e-05	160	142	6	76f49b8b4450fa8acd36326bfa36a5d1f4bd95fb
ToppCell	3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LDOC1 ARVCF EFHD1 ATP6V0A4 NGFR ESPL1	1.61e-05	167	142	6	49d9220f22d10ff06c0512c9c40c26ad51728e4f
ToppCell	3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LDOC1 ARVCF EFHD1 ATP6V0A4 NGFR ESPL1	1.61e-05	167	142	6	7ec032a98a13504d15c7e3a4e259278d07f40180
ToppCell	3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LDOC1 ARVCF EFHD1 ATP6V0A4 NGFR ESPL1	1.61e-05	167	142	6	5e3588eee73693a996bb4846427cf0038ceafbca
ToppCell	NS-critical-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RUNX1T1 DST EFHD1 ATP6V0A4 NGFR MTUS2	1.67e-05	168	142	6	6a233045638cb83dab64789b996b7598c325001e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC88C CROCC2 BEST4 KIF19 CFAP74 CFAP53	1.72e-05	169	142	6	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPP38 RNF213 ESYT2 DST DCHS1 RIPOR1	2.24e-05	177	142	6	8dfadd9852e0c256363471a7cfe6af120c8c51e0
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPP38 RNF213 ESYT2 DST DCHS1 RIPOR1	2.24e-05	177	142	6	767b2af5f224d100b22bed32f86cec1cd17e8711
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPP38 RNF213 ESYT2 DST DCHS1 RIPOR1	2.24e-05	177	142	6	5ef2527e9b41e62f1724cdabaad9d8979266bb7d
ToppCell	E18.5-Endothelial-Endothelial_lymphatic\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPP38 RNF213 ESYT2 DST DCHS1 RIPOR1	2.24e-05	177	142	6	ae1d2fdd4f67f50c906b27ea084de058c6908aa2
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	IQANK1 CROCC2 BEST4 KIF19 CFAP74 CFAP99	2.54e-05	181	142	6	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL3 TONSL NGFR MSS51 TCFL5 CNP	2.70e-05	183	142	6	8330c39184ce076e1f95fd3725b68af551d89db0
ToppCell	critical-Epithelial-Ionocyte\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RUNX1T1 DST EFHD1 ATP6V0A4 NGFR MTUS2	2.78e-05	184	142	6	58d36577eff814d46d72f031f3533d71549e3d6e
ToppCell	(210)_NKT_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	DLG5 TSPOAP1 AKNA CCDC88C SYNE2 ANKS3	3.53e-05	192	142	6	08dc0c019c594da7b9944db8fd706aa7780e6ae9
ToppCell	(21)_NKT_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	DLG5 TSPOAP1 AKNA CCDC88C SYNE2 ANKS3	3.53e-05	192	142	6	b0a573ddde2978485a857b8261ee1ee5ef68ecef
ToppCell	Club_cells\|World / lung cells shred on cell class, cell subclass, sample id	DSP CRACR2B EFHD1 SYNE2 INAVA MUC5AC	3.64e-05	193	142	6	9d3165dc5763a07a7d873f497624d9d6528fa2db
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNM AKNA RNF213 CCDC88C SYNE2 KIF19	3.74e-05	194	142	6	e72be6dc2711c1d4f16943c8615cf9dc2e961ff3
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SYNM AKNA RNF213 CCDC88C SYNE2 KIF19	3.74e-05	194	142	6	ac03be73fdc32dacd4a450c0fb28617e043b8444
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SYNM AKNA RNF213 CCDC88C SYNE2 KIF19	3.74e-05	194	142	6	7ab4418a8a12c488d74af3676bdac672628da80c
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNM AKNA RNF213 CCDC88C SYNE2 KIF19	3.74e-05	194	142	6	760761ce7d22edf9a8cec71e8ab0caa273fce3f7
ToppCell	3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DLG5 SYNM NAIP BCR DLC1 RIPOR1	3.85e-05	195	142	6	6a0460d949ccda7c9fe76870d3ee6c2f60677d61
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RHPN1 CROCC2 BEST4 ATP6V0A4 KIF19 CFAP74	3.85e-05	195	142	6	79dc031258579ea328181dda33710dd897f1064a
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAM74A1 CROCC2 KIF19 CFAP74 CFAP53 CFAP99	4.19e-05	198	142	6	f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	DSP TMEM63B HEATR5A IL17RE SYNE2 HPS5	4.19e-05	198	142	6	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	Bronchus_Control_(B.)-Endothelial-TX\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	APC2 SPTBN5 KCNG2 DST ESPL1 UNC80	4.19e-05	198	142	6	feac39036b5c0ab97b524cc366286942d136d42f
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DSP TMEM63B HEATR5A ANKRD6 IL17RE SYNE2	4.31e-05	199	142	6	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SPDL1 ARHGEF39 SYNE2 NCAPD2 CDC6 ESPL1	4.31e-05	199	142	6	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	OAS1 RNF213 BCR SH2B2 DLC1 SYNE2	4.43e-05	200	142	6	edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CROCC2 BEST4 KIF19 CFAP74 CFAP53 CFAP99	4.43e-05	200	142	6	af6a551f83808c1c839df7ba7b1702ca28ea6e1b
ToppCell	Control-Control-Lymphocyte-T/NK-CD8+_Tem\|Control / Disease, condition lineage and cell class	SYNM AKNA RNF213 CCDC88C SYNE2 KIF19	4.43e-05	200	142	6	fddb3df5b90eb97ef8ed80fac320c1a90903f012
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CROCC2 BEST4 KIF19 CFAP74 CFAP53 CFAP99	4.43e-05	200	142	6	73ac1cf40ddd764be1100cbfaaa29563665457d8
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	AIF1L EFHD1 INAVA CNP SEC14L5	1.12e-04	148	142	5	44128692824ca419fface0af41099c17135933ce
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	AIF1L EFHD1 INAVA CNP SEC14L5	1.12e-04	148	142	5	d60f93311cfa718d026a0dbf61771bbbcbb79146
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte-Oligo\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	AIF1L EFHD1 INAVA CNP SEC14L5	1.20e-04	150	142	5	b30f52b94ce772632a1f2f5e0837db876cf92651
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	AIF1L EFHD1 INAVA CNP SEC14L5	1.20e-04	150	142	5	05b9a9cbc5a95cdaf45d5f173e132acd4da9aa8a
ToppCell	PND01-03-samps-Myeloid-Macrophage-macrophage-B\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	COMTD1 ARHGEF39 NCAPD2 CFAP53 RUFY4	1.27e-04	152	142	5	5ce8920aedd39a4daf7082153b5e213707c14227
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CARMIL3 DLC1 MSS51 HDAC10 CDC6	1.62e-04	160	142	5	1a9329d8183296f36928bd9e96f10db9f04ce326
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CARD10 FAM74A1 KIF19 TONSL CFAP53	1.62e-04	160	142	5	33050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANKRD6 CXorf65 SPATA2L AGRP CORO7	1.71e-04	162	142	5	adf545cf9357556e2ce7affed01c2f6a24b0581d
ToppCell	Mild-MAIT\|World / Disease group and Cell class	DSP OAS1 PPFIA3 IL17RE CNP	1.81e-04	164	142	5	21dc02997dfae73cf70ce291661928526605dba1
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	EID2 SH2B2 MED22 TONSL DCHS1	2.03e-04	168	142	5	8697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCDHA5 AIF1L FAM74A1 DST CNP	2.03e-04	168	142	5	af82e07d1eec51fc6530155f37addbce6221885d
ToppCell	BAL-Control-cDC_6\|Control / Compartment, Disease Groups and Clusters	SYNM FOSL2 SPDL1 CCDC88C USP35	2.03e-04	168	142	5	65ec473cff748b334c0a66e33bc34a8465fe7631
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AIF1L DST USH1G GAL3ST3 NGFR	2.09e-04	169	142	5	2456b3e7776e8a2214972be1b4d66a3ca5480ae0
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Deuterosomal\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CROCC2 KIF19 CFAP74 CCDC188 CFAP99	2.20e-04	171	142	5	52aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocye.Tnr.Bmp4_(Bmp4)-\|Striatum / BrainAtlas - Mouse McCarroll V32	RASSF10 S1PR2 KIF19 INAVA	2.23e-04	93	142	4	ea380272fdcb29c5d77bd9bad33d4c622a263db9
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P2-Tnr\|Striatum / BrainAtlas - Mouse McCarroll V32	RASSF10 S1PR2 KIF19 INAVA	2.23e-04	93	142	4	a444550ec6e6c580ec23b43737187f94a2565585
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocye.Tnr.Bmp4_(Bmp4)\|Striatum / BrainAtlas - Mouse McCarroll V32	RASSF10 S1PR2 KIF19 INAVA	2.23e-04	93	142	4	7b41af7494d78e94b5e7c9728b287833e8673fa4
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P2\|Striatum / BrainAtlas - Mouse McCarroll V32	RASSF10 S1PR2 KIF19 INAVA	2.23e-04	93	142	4	d6a11279657854425ecb1350b9802d9eaad7b24a
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPDL1 ARHGEF39 IL17RE NCAPD2 CDC6	2.26e-04	172	142	5	ba36581ae339191a12a6d3ead39eaf69d78be10e
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	TSPOAP1 NAIP CRACR2B FAM20C TXLNG	2.32e-04	173	142	5	42c911ed16fabdabef063830e8407192d8bde950
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM58 ARHGEF39 NCAPD2 CDC6 ESPL1	2.39e-04	174	142	5	c26eac176e9b0cba385630fdc60e0314a4e4caac
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	PFAS FAAP100 DST CORO7 RUBCN	2.39e-04	174	142	5	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AIF1L DST NGFR CNP CCDC188	2.39e-04	174	142	5	412ccc099028a372b9d953363984c2da54b2187f
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASSF10 ANKRD6 BCR RHPN1 EFHD1	2.45e-04	175	142	5	9d082ba0e350162aa6e71b668be074b12a27c7ab
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASSF10 ANKRD6 BCR RHPN1 EFHD1	2.45e-04	175	142	5	f641f34b52aec5d047430a6f9d026e915da6c11d
ToppCell	NS-moderate-d_07-13-Lymphoid-NK\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RUNX1T1 TYR DLC1 DCHS1 NGFR	2.45e-04	175	142	5	f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCell	NS-moderate-d_07-13-Epithelial-Ionocyte\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RUNX1T1 DST EFHD1 ATP6V0A4 NGFR	2.58e-04	177	142	5	99500aed584f793aaf308f8afbf5d1c6a9b4ee55
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	DSP CRACR2B EFHD1 INAVA MUC5AC	2.72e-04	179	142	5	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	NS-moderate-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RUNX1T1 DST EFHD1 ATP6V0A4 NGFR	2.79e-04	180	142	5	8af8b4af2dc72223ac71fc027e0d4280c5dd81f8
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-4\|TCGA-Endometrium / Sample_Type by Project: Shred V9	CROCC2 KIF19 CFAP74 CFAP53 CFAP99	2.86e-04	181	142	5	51d91b923920463245e95d65c6a5197e21d34d73
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AIF1L DST NGFR CNP SEC14L5	2.94e-04	182	142	5	ecb5624c9074cc6449fad961df54c926c2681d54
ToppCell	NS-critical-d_07-13-Epithelial-Ionocyte\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RUNX1T1 DST EFHD1 NGFR MTUS2	3.01e-04	183	142	5	ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	DSP OAS1 RNF213 DST SYNE2	3.01e-04	183	142	5	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	DSP OAS1 SH2B2 RUBCN CNP	3.01e-04	183	142	5	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 IL17RE NGFR INAVA UNC80	3.09e-04	184	142	5	6388c47b7f1d8203e3069eba0e74107256dcae51
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOSL2 CRACR2B LDOC1 MSANTD1 GAL3ST3	3.09e-04	184	142	5	e0beb016823514eebdbfc13beb0807efb4470f08
ToppCell	COPD-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	TSPOAP1 BCR DST HPS5 MTUS2	3.09e-04	184	142	5	42d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCell	droplet-Heart-4Chambers-18m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 IL17RE NGFR INAVA UNC80	3.09e-04	184	142	5	d83ae1dc64aa1b27d3b524c137567418cc0ff8c6
ToppCell	COVID-19_Severe-gd_T\|COVID-19_Severe / Disease condition and Cell class	TSPOAP1 AKNA RNF213 SYNE2 RUBCN	3.09e-04	184	142	5	791f1bcb954aadc63d4117c400537d036f68734d
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	UROC1 CROCC2 CFAP74 CFAP53 CFAP99	3.16e-04	185	142	5	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1L DST EFHD1 SYNE2 CFAP74	3.24e-04	186	142	5	8eafd4bea692f7ef33de27dd53f9d1fe67deaad8
ToppCell	IPF-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	TSPOAP1 BCR MAP3K13 HPS5 MTUS2	3.24e-04	186	142	5	962c2dada19185628ead77c32fcb07fa95114247
ToppCell	droplet-Lung-nan-18m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 KLHL40 RASSF10 CFAP53 TCFL5	3.24e-04	186	142	5	740fd06bcd3b24e6ff2ecf8080f378afc3e95084
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|bone_marrow / Manually curated celltypes from each tissue	NAIP FAM20C NCAPD2 PLEC ESPL1	3.24e-04	186	142	5	e82d5e7a976b9cfa2b4640c7a7cd1cfea19c4806
ToppCell	droplet-Tongue-nan-24m-Epithelial-suprabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP DLC1 EFHD1 SYNE2 ATP6V0A4	3.24e-04	186	142	5	2913b5fd0617d024d600ba7015ec7b1961dade83
ToppCell	droplet-Lung-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 KLHL40 RASSF10 CFAP53 TCFL5	3.24e-04	186	142	5	5ab43a298d23238b34e898d11decf0ad81d1b14e
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOSL2 CARD10 CRACR2B RUNX1T1 DLC1	3.32e-04	187	142	5	3548a9914c2b2f5d805798ce22ab26eab6d03897
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma\|TCGA-Prostate / Sample_Type by Project: Shred V9	FAAP100 LETM1 RHPN1 HOXC6 ARVCF	3.32e-04	187	142	5	fa0452f3382c22c0391b241d06504fda3c6a19f0
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOSL2 CARD10 CRACR2B RUNX1T1 DLC1	3.32e-04	187	142	5	f4de4b7af1fdfbd628b1f509c060c1079d2e5437
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CROCC2 KIF19 CFAP74 CFAP53 CFAP99	3.32e-04	187	142	5	9e10ed56090d82589bc457788282f664b70ace4b
ToppCell	TCGA-Prostate-Primary_Tumor\|TCGA-Prostate / Sample_Type by Project: Shred V9	FAAP100 LETM1 RHPN1 HOXC6 ARVCF	3.32e-04	187	142	5	3e6a95c912dad5d61e10497ffaafd2b9027cd13a
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOSL2 CARD10 CRACR2B RUNX1T1 DLC1	3.32e-04	187	142	5	81754e965848b718be20ee97ce072ce426938a69
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRIM58 FOSL2 TONSL DCHS1 TCFL5	3.41e-04	188	142	5	524d1d928c9386acf20e53d31894107dd7290dc7
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	CROCC2 KIF19 CFAP74 CFAP53 CFAP99	3.41e-04	188	142	5	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	T_cells-ISG-high_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	OAS1 RNF213 SYNE2 CNP RUFY4	3.41e-04	188	142	5	6f8946d4710f6e32c937213f99b790b098b8819c
ToppCell	IPF-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	TSPOAP1 BCR MAP3K13 HPS5 MTUS2	3.41e-04	188	142	5	47bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRIM58 FOSL2 TONSL DCHS1 TCFL5	3.41e-04	188	142	5	1b57995d70cf81212e8d46dfaf44dbaf9c7bc4d5
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRIM58 FOSL2 TONSL DCHS1 TCFL5	3.41e-04	188	142	5	cd2d1f8e43c252dd8730a5758458ef63e7ffc836
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRIM58 FOSL2 TONSL DCHS1 TCFL5	3.41e-04	188	142	5	f5a2f324f3f6c5078d57130392d3f1ba74f29094
ToppCell	5'-Airway_Nasal-Endothelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRIM58 FOSL2 TONSL DCHS1 TCFL5	3.41e-04	188	142	5	6c9d5e4014f807149328ff4eabd5e86dfe18094d
ToppCell	facs-Lung-EPCAM-18m-Epithelial-Basal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 DSP IL17RE NGFR INAVA	3.49e-04	189	142	5	783c1db856f2defe6f3b8748dd0bc29a8102f6d1
Drug	butyronitrile	DST PPP4C PLEC HPS5	2.98e-06	17	139	4	CID000008008
Disease	aspartate aminotransferase to alanine aminotransferase ratio	IQANK1 EPPK1 AKNA BAZ1B MSANTD1 EFHD1 PLEC	1.15e-04	239	134	7	EFO_0010934
Disease	autosomal recessive osteopetrosis 1 (implicated_via_orthology)	ATP6V0A4 CCDC154	2.03e-04	5	134	2	DOID:0110942 (implicated_via_orthology)
Disease	epidermolysis bullosa simplex (is_implicated_in)	DST PLEC	4.24e-04	7	134	2	DOID:4644 (is_implicated_in)
Disease	cerebral cavernous malformation (implicated_via_orthology)	CDC42BPG RNF213	1.10e-03	11	134	2	DOID:0060669 (implicated_via_orthology)
Disease	pulmonary fibrosis	SPDL1 MUC5AC	1.10e-03	11	134	2	EFO_0009448
Disease	Situs Inversus	CFAP53 ANKS3	1.10e-03	11	134	2	C0037221
Disease	Cleft palate, tobacco smoke exposure measurement, cleft lip, parental genotype effect measurement	RUNX1T1 SHKBP1	1.10e-03	11	134	2	EFO_0003959, EFO_0005939, EFO_0009115, HP_0000175
Disease	von Willebrand factor measurement, coagulation factor measurement	ANKRD6 SAFB2	1.31e-03	12	134	2	EFO_0004629, EFO_0004634
Disease	immature platelet count	PPP4R1 ESYT2 PLEC SEC14L5	1.41e-03	106	134	4	EFO_0803544
Disease	non-high density lipoprotein cholesterol measurement	MYO1H AKNA HEATR5A CNIH3 ESYT2 DLC1 MACO1 SYNE2 NAIF1 ABCG8	1.59e-03	713	134	10	EFO_0005689
Disease	Hermansky-Pudlak syndrome (implicated_via_orthology)	VPS33A HPS5	1.80e-03	14	134	2	DOID:3753 (implicated_via_orthology)
Disease	immature platelet fraction	PPP4R1 ESYT2 PLEC SEC14L5	1.84e-03	114	134	4	EFO_0009187
Disease	idiopathic pulmonary fibrosis	DSP SPDL1 MUC5AC	2.24e-03	57	134	3	EFO_0000768
Disease	2-hydroxyglutarate measurement	GAL3ST3 PCNT	2.36e-03	16	134	2	EFO_0021506
Disease	mean platelet volume	TRIM58 DNM1L SHKBP1 MSANTD1 ESYT2 SYNE2 RIPOR1 PLEC ESPL1 ABCG8 RNF138 SEC14L5	2.42e-03	1020	134	12	EFO_0004584
Disease	acne	CDC42BPG RASSF10 DLC1 INAVA	2.58e-03	125	134	4	EFO_0003894
Disease	Moyamoya Disease	RNF213 PCNT	2.66e-03	17	134	2	C0026654
Disease	cutaneous melanoma, hair color	BCR TYR SYNE2	2.85e-03	62	134	3	EFO_0000389, EFO_0003924
Disease	platelet measurement	EPPK1 TRIM58 DNM1L ESYT2 PLEC SEC14L5	3.24e-03	315	134	6	EFO_0005036
Disease	Chronic myeloproliferative disorder	CDC6 PCNT	3.33e-03	19	134	2	C1292778
Disease	low density lipoprotein cholesterol measurement, physical activity	PFAS MACO1 ABCG8	3.40e-03	66	134	3	EFO_0003940, EFO_0004611
Disease	interstitial lung disease	DSP SPDL1 MUC5AC	3.55e-03	67	134	3	EFO_0004244
Disease	Sclerocystic Ovaries	CARMIL3 RHPN1 TONSL CDC6	4.28e-03	144	134	4	C1136382
Disease	Polycystic Ovary Syndrome	CARMIL3 RHPN1 TONSL CDC6	4.28e-03	144	134	4	C0032460
Disease	Seckel syndrome	CDC6 PCNT	4.46e-03	22	134	2	C0265202

Protein segments in the cluster

Peptide	Gene	Start	Entry
REAERRIRECAKLQR	USH1G	141	Q495M9
RRDGRIRDDIALCLL	BEST4	196	Q8NFU0
CLLIAVRTNRARDIR	NAIP	576	Q13075
LQDREPRSSRRCVRL	AGRP	76	O00253
RQERRLAEINREFLC	AIF1L	21	Q9BQI0
LETRRCVEARLRLET	ADCY8	351	P40145
RRCLQEDVERVQRLS	FAM74A1	76	Q5RGS3
CRALALLEDEERVVR	ESYT2	161	A0FGR8
VEASDRLQRRVEELC	RNF40	196	O75150
MERCRILLEAARIIR	ALDH9A1	71	P49189
VSRLEEECALLRRAR	CARD10	241	Q9BWT7
ARRRLRECEGLVDAL	ARVCF	536	O00192
RLQEELRRCRERLQA	CCDC88B	331	A6NC98
LVALRIQCDALERRR	CXorf65	106	A6NEN9
LSAREQRDCEVIERL	DNM1L	636	O00429
IEQELERCKASIRRL	BCR	31	P11274
LVRLCLRRSDVQEES	BAZ1B	691	Q9UIG0
EELRRCRRLGEERAT	ARHGEF2	816	Q92974
KRVEDVIAELRLRQC	ABCG8	186	Q9H221
EAARLRAELERERVC	ANKRD24	946	Q8TF21
RKLQDCRELESSRRL	CCDC22	436	O60826
CRELESSRRLAEIQE	CCDC22	441	O60826
QRCERATRSLLRELL	CCDC154	91	A6NI56
VERLSAERTECLNRL	ANKRD6	466	Q9Y2G4
RKRACTARELLETER	ARHGEF39	21	Q8N4T4
REAERQLVLRLKERC	MTUS2	991	Q5JR59
RECFQRISRRLRAVL	R3HDM4	166	Q96D70
ELARRCDDLLRLQEQ	RASSF10	321	A6NK89
ERISERQRILCLPQR	RBM41	126	Q96IZ5
LALERELDQRRRECQ	RIMBP3B	571	A6NNM3
LCLDLRGTERREERR	RIMBP3B	1386	A6NNM3
LALERELDQRRRECQ	RIMBP3C	571	A6NJZ7
LCLDLRGTERREERR	RIMBP3C	1386	A6NJZ7
FDRLLRESQREVLRL	TSPOAP1	261	O95153
ERQLLRAALRRADCL	P3H3	111	Q8IVL6
LIRQLLCRQEERLGR	CDC42BPG	311	Q6DT37
EQRRRCELISQLRAL	CFAP99	456	D6REC4
RRLSRAVEETCREVR	MSANTD1	231	Q6ZTZ1
IYLVCVARRLDREER	DCHS1	421	Q96JQ0
EQLERRCATLEREQR	LZTS2	416	Q9BRK4
RLLVCERASLLRQVR	LDOC1	31	O95751
RRVCQELRLVAVDRL	MSS51	146	Q4VC12
TRRSLTVLRRCQEAD	RUNX1T1	371	Q06455
ILRRVNAVATCRREL	NAIF1	51	Q69YI7
EVRNIRLRLENCEDR	DST	1071	Q03001
RLRLENCEDRLIRQI	DST	1076	Q03001
ALERQRAEVCQLRER	PPFIA3	241	O75145
RTLQEECDRKLITLR	MED22	106	Q15528
ILCLELERRREAFTN	HPS5	991	Q9UPZ3
RQSRLELCSRLEREA	IL17RE	646	Q8NFR9
LTRRERRQFLRICAD	LETM1	191	O95202
RLCGRVQEEVRALRL	CARMIL3	691	Q8ND23
LRRLIDQRDECTELI	CCDC88C	196	Q9P219
KANRVERLELELTRC	CCDC88C	321	Q9P219
DVREVELMRCLRLRQ	CORO7	791	P57737
ECTETLRNRIRELEA	MACO1	501	Q8N5G2
ERCCLRRLRRREEEA	KCNG2	116	Q9UJ96
RVEAAFLCRLRRDAL	ERFE	201	Q4G0M1
FLCRLRRDALVERRA	ERFE	206	Q4G0M1
ERDSIRTLCDNLRRE	DLG5	536	Q8TDM6
RTLCDNLRRERDRAV	DLG5	541	Q8TDM6
KARELREECRSLRSR	L1RE1	96	Q9UN81
EKVRERLRVALERCS	PPFIA1	176	Q13136
RLRVALERCSLLEEE	PPFIA1	181	Q13136
CRLLPRAFLESRVER	KLHL40	226	Q2TBA0
LRRQLDCVSGDRVRL	KRT82	176	Q9NSB4
VRRCLNLEERVVLKR	NLRP5	516	P59047
RRPEEITRLQCRAES	MUC5AC	3261	P98088
RRPEEITRLQCRAES	MUC5AC	4666	P98088
EIRRQLEACQRERAF	OAS1	101	P00973
NSRIDREELCRRRAE	PCDHA5	86	Q9Y5H7
LREVQTLRDRLCTED	FAAP100	841	Q0VG06
LRCQVELDRRQARRA	PCNT	1941	O95613
KNQERILREVCRVLR	METTL7A	151	Q9H8H3
LTRRRRIEIANALCL	HOXC6	166	P09630
CRELRARGRRLEETL	KIF19	536	Q2TAC6
CIHRLDEELIRRRRE	MAP3K13	446	O43283
VNSRIDREELCRRSA	PCDHA4	86	Q9UN74
QFRERCEELRVELLS	CFAP53	156	Q96M91
ARELREARQRLLRRC	GAL3ST3	321	Q96A11
RVSLKCRRQLRVEEL	GLG1	796	Q92896
ATIRLLEELDRERCF	APC2	126	O95996
RSDAERRQACDAILR	ESPL1	41	Q14674
DRLRQRGLEQRCLRL	HDAC10	36	Q969S8
RRAVLACLRQLVQRE	HEATR5A	1081	Q86XA9
RREELALRRERSCRA	CROCC2	531	H7BZ55
PRDRRRLEQELCQLE	GJA9	126	P57773
VCRRLIVATRERDVR	EPM2AIP1	41	Q7L775
LDRRLRVVLKAVRDC	FAM20C	546	Q8IXL6
LEILRERAQCRTRAR	CCDC188	301	H7C350
RLQAEIKRIEERCRR	DSP	1901	P15924
LFLRQERDARQRLVC	F8A1;	96	P23610
RRRRQTASALDCDLR	CCDC102A	391	Q96A19
CVRNLNERIRRDVRV	COMTD1	231	Q86VU5
IRLCLARSAAERRNV	TMEM63B	596	Q5T3F8
LRELNTRLRDDRDAC	CRACR2B	341	Q8N4Y2
CRNRRRELTEKLQAE	FOSL2	141	P15408
AICELQEEVSRLRLR	AKNA	1076	Q7Z591
DVRKALDVCRRAIEI	CDC6	386	Q99741
CRRRDIRILVLDDTN	CNP	111	P09543
IQELEERRRRFVEAC	EID2	171	Q8N6I1
RAVVESCLLEQDRAR	ANKS3	536	Q6ZW76
LACKLERRLRREEAE	EFHD1	6	Q9BUP0
EDCRRRELLQAIGRK	CCDC177	636	Q9NQR7
RCERLQARREALARQ	RUBCN	931	Q92622
ERSCRLRVDAPRLLR	SEC14L5	56	O43304
RSRDLRREVLRPLQC	S1PR2	291	O95136
CRALRETKNRLEREV	POLRMT	446	O00411
LEARLEACLEELRRL	INAVA	126	Q3KP66
ELRACRQRRDLIDKQ	CFAP74	101	Q9C0B2
ELVRVLCRRLDEATL	SZT2	2176	Q5T011
LSEDYRQCLERELRR	SPATA2L	6	Q8IUW3
ERDCIAVLERISRLA	PPP4R1	81	Q8TF05
TRALERRELLLVLVC	RPP38	121	P78345
LCLRVAIRKQEIEDR	SYNE2	5901	Q8WXH0
VCRVRELERENLLLE	SYNM	26	O15061
LALERELDQRRRECQ	RIMBP3	571	Q9UFD9
QLSEELRCALRDARV	EPPK1	2426	P58107
QLSEELRCALRDARV	EPPK1	4561	P58107
ISRERAVELLRKCLE	PSMB2	151	P49721
VTRRERACPERALDL	RNF138	61	Q8WVD3
LREQLSRCQEERAEL	RUFY4	446	Q6ZNE9
ITNLRCRLKEAEEER	SPDL1	6	Q96EA4
LVRRLQLREELDRSS	SHKBP1	106	Q8TBC3
VQVRERLASRCRDAR	SLC26A10	486	Q8NG04
RRREGLKRRQEEVCD	SIRT7	66	Q9NRC8
RRLQRRVALAECEDS	IQANK1	176	A8MXQ7
LCRVLREVDLLRAVI	RHPN1	426	Q8TCX5
LDRDAIEALCRRLNT	DLC1	491	Q96QB1
DLEHCLQLRRRLREF	SPTBN5	2286	Q9NRC6
SGELCRRRVLREEQE	NCAPD2	946	Q15021
RERLRNIERICFLLR	CNIH3	51	Q8TBE1
LQEVARIRLCLDRAA	RNF213	4226	Q63HN8
REEFRRPRESLLNIC	UNC80	2486	Q8N2C7
RRIQRADLVESLCSE	NGFR	406	P08138
DSLDRCIQRLREARK	UROC1	291	Q96N76
RDRCKDRIQRQLEIT	STX1B	141	P61266
SRRLCAEDRDALRQL	TONSL	1341	Q96HA7
RRIVLVDDRECPVRR	PFAS	596	O15067
FALLRREVLRTVCER	USP35	121	Q9P2H5
NCTERRLLVRRNIFD	TYR	111	P14679
CRLLLRRAVAEERFR	SH2B2	221	O14492
ERLQLECQRQRLERE	SAFB2	666	Q14151
LRSEFERLECLQRIV	PLEC	521	Q15149
RRCESLERILRFLED	ATP6V0A4	56	Q9HBG4
REAVRRELREFLDKC	VPS33A	16	Q96AX1
LERLEKLCRALQTER	TXLNG	431	Q9NUQ3
LERLLREARVLEAVC	RIPOR1	931	Q6ZS17
DRRRRIRICCDELNL	TCFL5	411	Q9UL49
DLDRQIEQLRRCELI	PPP4C	6	P60510
ELCALRELRQRLEDA	WWC3	986	Q9ULE0
LRRLEAEERATLQRL	TRIM58	201	Q8NG06
RDIEERSRSCNIRLI	L1TD1	691	Q5T7N2
ILRECFLLAELENRR	MYO1H	551	Q8N1T3
LRIEECAARRQARID	MMUT	466	P22033
QRLEESICINDRLRE	PDE4DIP	1856	Q5VU43