Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL7A1 VWF COMP LAMB1 LAMC2 COL25A1 SBSPON	5.10e-05	188	102	7	GO:0005201
GeneOntologyMolecularFunction	heparin binding	COMP ADAMTS1 LAMC2 COL25A1 SMOC2 RSPO2 VEGFA	5.82e-05	192	102	7	GO:0008201
GeneOntologyMolecularFunction	glycosaminoglycan binding	COMP ADAMTS1 LAMC2 COL25A1 SMOC2 GFRA2 RSPO2 VEGFA	7.00e-05	268	102	8	GO:0005539
GeneOntologyMolecularFunction	sulfur compound binding	COMP ADAMTS1 LAMC2 COL25A1 SMOC2 GFRA2 RSPO2 VEGFA	2.52e-04	323	102	8	GO:1901681
GeneOntologyMolecularFunction	peptidyltransferase activity	GGT1 GGT3P	3.82e-04	6	102	2	GO:0000048
GeneOntologyMolecularFunction	leukotriene-C(4) hydrolase	GGT1 GGT3P	3.82e-04	6	102	2	GO:0002951
GeneOntologyMolecularFunction	thiol oxidase activity	ERO1A GFER	3.82e-04	6	102	2	GO:0016972
GeneOntologyMolecularFunction	clathrin light chain binding	CLTCL1 CLTC	5.34e-04	7	102	2	GO:0032051
GeneOntologyMolecularFunction	leukotriene C4 gamma-glutamyl transferase activity	GGT1 GGT3P	7.09e-04	8	102	2	GO:0103068
GeneOntologyMolecularFunction	glutathione hydrolase activity	GGT1 GGT3P	9.09e-04	9	102	2	GO:0036374
GeneOntologyMolecularFunction	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	ERO1A GFER	1.38e-03	11	102	2	GO:0016670
GeneOntologyMolecularFunction	P-type calcium transporter activity	ATP2A1 ATP2A2	1.38e-03	11	102	2	GO:0005388
GeneOntologyMolecularFunction	semaphorin receptor activity	PLXNB2 PLXNA1	1.65e-03	12	102	2	GO:0017154
GeneOntologyBiologicalProcess	positive regulation of mammary gland epithelial cell proliferation	KDM5B CCND1 MST1 MST1L	7.54e-08	9	104	4	GO:0033601
GeneOntologyBiologicalProcess	regulation of mammary gland epithelial cell proliferation	KDM5B CCND1 MST1 MST1L	3.42e-06	21	104	4	GO:0033599
GeneOntologyBiologicalProcess	mammary duct terminal end bud growth	KDM5B MST1 MST1L	1.02e-05	9	104	3	GO:0060763
GeneOntologyBiologicalProcess	mammary gland epithelial cell proliferation	KDM5B CCND1 MST1 MST1L	2.52e-05	34	104	4	GO:0033598
GeneOntologyBiologicalProcess	positive regulation of endoplasmic reticulum calcium ion concentration	ATP2A1 ATP2A2	7.53e-05	3	104	2	GO:0032470
GeneOntologyBiologicalProcess	gland development	KDM5B VWF INSM1 CCND1 ZBTB7B GFER MST1 TP63 MST1L PLXNA1 VEGFA	1.18e-04	558	104	11	GO:0048732
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL7A1 VWF COMP ADAMTS2 ADAMTS1 LAMB1 LAMC2 COL25A1 SMOC2 PLXNB2 MST1 CLEC14A SBSPON VEGFA	3.76e-07	530	104	14	GO:0062023
GeneOntologyCellularComponent	extracellular matrix	COL7A1 VWF COMP ADAMTS2 ADAMTS1 LAMB1 LAMC2 COL25A1 SMOC2 PLXNB2 MST1 CLEC14A SBSPON OTOG VEGFA	8.65e-07	656	104	15	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL7A1 VWF COMP ADAMTS2 ADAMTS1 LAMB1 LAMC2 COL25A1 SMOC2 PLXNB2 MST1 CLEC14A SBSPON OTOG VEGFA	8.98e-07	658	104	15	GO:0030312
GeneOntologyCellularComponent	laminin-2 complex	LAMB1 LAMC2	2.45e-05	2	104	2	GO:0005607
GeneOntologyCellularComponent	basement membrane	COL7A1 ADAMTS1 LAMB1 LAMC2 SMOC2 VEGFA	3.32e-05	122	104	6	GO:0005604
GeneOntologyCellularComponent	clathrin complex	CLTCL1 CLTC	8.63e-04	9	104	2	GO:0071439
GeneOntologyCellularComponent	platelet dense tubular network membrane	ATP2A1 ATP2A2	8.63e-04	9	104	2	GO:0031095
GeneOntologyCellularComponent	laminin complex	LAMB1 LAMC2	1.07e-03	10	104	2	GO:0043256
GeneOntologyCellularComponent	platelet dense tubular network	ATP2A1 ATP2A2	1.31e-03	11	104	2	GO:0031094
MousePheno	dermal-epidermal separation	COL7A1 LAMC2 TP63	1.71e-05	9	84	3	MP:0011160
Domain	TSP1	ADAMTS2 ADAMTS1 SEMA5B SBSPON RSPO2 C9	1.54e-06	65	103	6	SM00209
Domain	TSP1_rpt	ADAMTS2 ADAMTS1 SEMA5B SBSPON RSPO2 C9	1.54e-06	65	103	6	IPR000884
Domain	TSP1	ADAMTS2 ADAMTS1 SEMA5B SBSPON RSPO2 C9	1.54e-06	65	103	6	PS50092
Domain	Znf_C2H2-like	AKAP8 ZNF559 INSM1 ZNF696 PRDM5 ZBTB7B ZNF623 ZNF800 PRDM8 WIZ ZNF732 MZF1 ZNF579 ZFP62 ZNF541 ZNF646	7.13e-06	796	103	16	IPR015880
Domain	Znf_C2H2	AKAP8 ZNF559 INSM1 ZNF696 PRDM5 ZBTB7B ZNF623 ZNF800 PRDM8 WIZ ZNF732 MZF1 ZNF579 ZFP62 ZNF541 ZNF646	8.21e-06	805	103	16	IPR007087
Domain	ZnF_C2H2	AKAP8 ZNF559 INSM1 ZNF696 PRDM5 ZBTB7B ZNF623 ZNF800 PRDM8 WIZ ZNF732 MZF1 ZNF579 ZFP62 ZNF541 ZNF646	8.60e-06	808	103	16	SM00355
Domain	-	ZNF559 INSM1 ZNF696 PRDM5 ZBTB7B ZNF623 ZNF800 PRDM8 ZNF732 MZF1 ZNF579 ZFP62 ZNF541 ZNF646	2.13e-05	679	103	14	3.30.160.60
Domain	ZINC_FINGER_C2H2_2	ZNF559 INSM1 ZNF696 PRDM5 ZBTB7B ZNF623 ZNF800 PRDM8 WIZ ZNF732 MZF1 ZNF579 ZFP62 ZNF541 ZNF646	2.21e-05	775	103	15	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF559 INSM1 ZNF696 PRDM5 ZBTB7B ZNF623 ZNF800 PRDM8 WIZ ZNF732 MZF1 ZNF579 ZFP62 ZNF541 ZNF646	2.28e-05	777	103	15	PS00028
Domain	Growth_fac_rcpt_	COMP CRIM1 LAMB1 LAMC2 DLL3 RSPO2 C9	2.51e-05	156	103	7	IPR009030
Domain	TSP_1	ADAMTS2 ADAMTS1 SEMA5B SBSPON C9	2.52e-05	63	103	5	PF00090
Domain	Znf_C2H2/integrase_DNA-bd	ZNF559 INSM1 ZNF696 PRDM5 ZBTB7B ZNF623 ZNF800 PRDM8 ZNF732 MZF1 ZNF579 ZFP62 ZNF541 ZNF646	2.71e-05	694	103	14	IPR013087
Domain	Clathrin_H-chain_propeller_rpt	CLTCL1 CLTC	3.01e-05	2	103	2	IPR022365
Domain	Clathrin-link	CLTCL1 CLTC	3.01e-05	2	103	2	PF09268
Domain	-	CLTCL1 CLTC	3.01e-05	2	103	2	2.130.10.110
Domain	Clathrin_H-chain_link/propller	CLTCL1 CLTC	3.01e-05	2	103	2	IPR016025
Domain	Clathrin_propel	CLTCL1 CLTC	3.01e-05	2	103	2	PF01394
Domain	Clathrin_heavy_chain	CLTCL1 CLTC	3.01e-05	2	103	2	IPR016341
Domain	Clathrin_H-chain_linker_core	CLTCL1 CLTC	3.01e-05	2	103	2	IPR015348
Domain	Clathrin_H-chain_propeller_N	CLTCL1 CLTC	3.01e-05	2	103	2	IPR001473
Domain	EGF-like_dom	COMP NRG2 LAMB1 LAMC2 CLEC14A DLL3 C9 OTOG	7.13e-05	249	103	8	IPR000742
Domain	Clathrin_H-chain_linker	CLTCL1 CLTC	9.00e-05	3	103	2	IPR012331
Domain	P-type_ATPase_IIA	ATP2A1 ATP2A2	9.00e-05	3	103	2	IPR005782
Domain	CLH	CLTCL1 CLTC	9.00e-05	3	103	2	SM00299
Domain	zf-C2H2	ZNF559 INSM1 ZNF696 PRDM5 ZBTB7B ZNF623 PRDM8 ZNF732 MZF1 ZNF579 ZFP62 ZNF541 ZNF646	1.12e-04	693	103	13	PF00096
Domain	VWC_out	VWF CRIM1 OTOG	1.48e-04	19	103	3	SM00215
Domain	PAN_AP	MST1 MST1L	2.98e-04	5	103	2	SM00473
Domain	EGF_1	COMP NRG2 LAMB1 LAMC2 CLEC14A DLL3 C9	5.30e-04	255	103	7	PS00022
Domain	EGF-like_CS	COMP NRG2 LAMB1 LAMC2 CLEC14A DLL3 C9	6.08e-04	261	103	7	IPR013032
Domain	Clathrin	CLTCL1 CLTC	6.21e-04	7	103	2	PF00637
Domain	GGT_peptidase	GGT1 GGT3P	6.21e-04	7	103	2	IPR000101
Domain	PAN	MST1 MST1L	6.21e-04	7	103	2	PS50948
Domain	G_GLU_TRANSPEPTIDASE	GGT1 GGT3P	6.21e-04	7	103	2	PS00462
Domain	Pan_app	MST1 MST1L	6.21e-04	7	103	2	IPR003609
Domain	G_glu_transpept	GGT1 GGT3P	6.21e-04	7	103	2	PF01019
Domain	CHCR	CLTCL1 CLTC	6.21e-04	7	103	2	PS50236
Domain	PAN_1	MST1 MST1L	6.21e-04	7	103	2	PF00024
Domain	Sema	PLXNB2 SEMA5B PLXNA1	6.54e-04	31	103	3	SM00630
Domain	Semap_dom	PLXNB2 SEMA5B PLXNA1	6.54e-04	31	103	3	IPR001627
Domain	Sema	PLXNB2 SEMA5B PLXNA1	6.54e-04	31	103	3	PF01403
Domain	SEMA	PLXNB2 SEMA5B PLXNA1	6.54e-04	31	103	3	PS51004
Domain	EGF_2	COMP NRG2 LAMB1 LAMC2 CLEC14A DLL3 C9	6.65e-04	265	103	7	PS01186
Domain	PSI	PLXNB2 SEMA5B PLXNA1	7.19e-04	32	103	3	PF01437
Domain	Plexin_repeat	PLXNB2 SEMA5B PLXNA1	7.19e-04	32	103	3	IPR002165
Domain	Clathrin_H-chain/VPS_repeat	CLTCL1 CLTC	8.25e-04	8	103	2	IPR000547
Domain	Plexin_cytopl	PLXNB2 PLXNA1	1.06e-03	9	103	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNB2 PLXNA1	1.06e-03	9	103	2	IPR013548
Domain	Plexin	PLXNB2 PLXNA1	1.06e-03	9	103	2	IPR031148
Domain	Hydrolase_3	ATP2A1 ATP2A2	1.32e-03	10	103	2	PF08282
Domain	-	MKRN3 MBNL1 ZC3H10	1.39e-03	40	103	3	4.10.1000.10
Domain	Rho_GTPase_activation_prot	TAGAP CHN1 PLXNB2 PLXNA1	1.43e-03	88	103	4	IPR008936
Domain	VWF_dom	VWF CRIM1 OTOG	1.60e-03	42	103	3	IPR001007
Domain	PSI	PLXNB2 SEMA5B PLXNA1	1.83e-03	44	103	3	IPR016201
Domain	TIL	VWF OTOG	1.92e-03	12	103	2	PF01826
Domain	C8	VWF OTOG	1.92e-03	12	103	2	PF08742
Domain	EGF_3	COMP NRG2 CLEC14A DLL3 C9 OTOG	1.93e-03	235	103	6	PS50026
Domain	EGF	COMP NRG2 LAMB1 LAMC2 CLEC14A DLL3	1.93e-03	235	103	6	SM00181
Domain	PSI	PLXNB2 SEMA5B PLXNA1	2.08e-03	46	103	3	SM00423
Domain	Unchr_dom_Cys-rich	VWF OTOG	2.26e-03	13	103	2	IPR014853
Domain	I-BAR_dom	BAIAP2 ACAP3	2.26e-03	13	103	2	IPR013606
Domain	C8	VWF OTOG	2.26e-03	13	103	2	SM00832
Domain	ZnF_C3H1	MKRN3 MBNL1 ZC3H10	2.35e-03	48	103	3	SM00356
Domain	zf-CCCH	MKRN3 MBNL1 ZC3H10	2.50e-03	49	103	3	PF00642
Domain	TIL_dom	VWF OTOG	2.62e-03	14	103	2	IPR002919
Domain	VWD	VWF OTOG	3.44e-03	16	103	2	SM00216
Domain	-	ATP2A1 ATP2A2	3.44e-03	16	103	2	1.20.1110.10
Domain	VWF_type-D	VWF OTOG	3.44e-03	16	103	2	IPR001846
Domain	VWFD	VWF OTOG	3.44e-03	16	103	2	PS51233
Domain	ATPase_P-typ_TM_dom	ATP2A1 ATP2A2	3.44e-03	16	103	2	IPR023298
Domain	VWD	VWF OTOG	3.44e-03	16	103	2	PF00094
Domain	VWA	COL7A1 VWF VWA3B	3.65e-03	56	103	3	PF00092
Domain	Kringle	MST1 MST1L	3.88e-03	17	103	2	IPR000001
Domain	TY	SMOC2 TG	3.88e-03	17	103	2	SM00211
Domain	ATPase_P-typ_cation-transptr_C	ATP2A1 ATP2A2	3.88e-03	17	103	2	IPR006068
Domain	-	SMOC2 TG	3.88e-03	17	103	2	4.10.800.10
Domain	Kringle_CS	MST1 MST1L	3.88e-03	17	103	2	IPR018056
Domain	Cation_ATPase_C	ATP2A1 ATP2A2	3.88e-03	17	103	2	PF00689
Domain	THYROGLOBULIN_1_2	SMOC2 TG	3.88e-03	17	103	2	PS51162
Domain	KRINGLE_2	MST1 MST1L	3.88e-03	17	103	2	PS50070
Domain	Thyroglobulin_1	SMOC2 TG	3.88e-03	17	103	2	IPR000716
Domain	Thyroglobulin_1	SMOC2 TG	3.88e-03	17	103	2	PF00086
Domain	Kringle	MST1 MST1L	3.88e-03	17	103	2	PF00051
Domain	KRINGLE_1	MST1 MST1L	3.88e-03	17	103	2	PS00021
Domain	THYROGLOBULIN_1_1	SMOC2 TG	3.88e-03	17	103	2	PS00484
Domain	KR	MST1 MST1L	3.88e-03	17	103	2	SM00130
Domain	Znf_CCCH	MKRN3 MBNL1 ZC3H10	4.03e-03	58	103	3	IPR000571
Domain	ZF_C3H1	MKRN3 MBNL1 ZC3H10	4.03e-03	58	103	3	PS50103
Domain	Cation_ATPase_N	ATP2A1 ATP2A2	4.35e-03	18	103	2	PF00690
Domain	Cation_ATPase_N	ATP2A1 ATP2A2	4.35e-03	18	103	2	SM00831
Domain	Prtase_inh_Kunz-CS	COL7A1 EPPIN	4.35e-03	18	103	2	IPR020901
Domain	BPTI_KUNITZ_2	COL7A1 EPPIN	4.84e-03	19	103	2	PS50279
Domain	ATPase_P-typ_cation-transptr_N	ATP2A1 ATP2A2	4.84e-03	19	103	2	IPR004014
Domain	Kunitz_BPTI	COL7A1 EPPIN	4.84e-03	19	103	2	PF00014
Domain	BPTI_KUNITZ_1	COL7A1 EPPIN	4.84e-03	19	103	2	PS00280
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS2 ADAMTS1 SEMA5B SBSPON	7.14e-05	39	81	4	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS2 ADAMTS1 SEMA5B SBSPON	7.14e-05	39	81	4	MM15165
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	COL7A1 VWF LAMB1 LAMC2 COL25A1 MST1 SBSPON	4.41e-07	153	105	7	25037231
Pubmed	cDNA cloning and chromosomal mapping of the mouse type VII collagen gene (Col7a1): evidence for rapid evolutionary divergence of the gene.	COL7A1 MST1 MST1L	5.31e-07	6	105	3	8325648
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL7A1 VWF LAMB1 LAMC2 COL25A1 PLXNB2 CLEC14A	7.95e-07	167	105	7	22159717
Pubmed	ERp57 is essential for efficient folding of glycoproteins sharing common structural domains.	ERO1A LAMB1 LAMC2 PLXNA1	9.45e-07	25	105	4	17170699
Pubmed	Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy.	CLTCL1 MAP1LC3A CLTC SEC16A	1.11e-06	26	105	4	24067654
Pubmed	Transcriptome analysis of mouse and human sinoatrial node cells reveals a conserved genetic program.	VWF SMOC2 GFRA2 VEGFA	2.64e-06	32	105	4	30936179
Pubmed	Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.	COL7A1 COMP ADAMTS1 LAMC2 SEMA5B DLL3 BAIAP2	3.65e-06	210	105	7	16537572
Pubmed	Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.	LAMB1 LAMC2 TG VEGFA	6.59e-06	40	105	4	27068110
Pubmed	Ontogenesis of the tear drainage system requires Prickle1-driven polarized basement membrane deposition.	LAMB1 TP63 CLTC	7.48e-06	13	105	3	33144400
Pubmed	Neddylation mediates ventricular chamber maturation through repression of Hippo signaling.	CCND1 MST1 TP63 MST1L	8.04e-06	42	105	4	29632206
Pubmed	Targeted disruption of the ATP2A1 gene encoding the sarco(endo)plasmic reticulum Ca2+ ATPase isoform 1 (SERCA1) impairs diaphragm function and is lethal in neonatal mice.	ATP2A1 ATP2A2	9.03e-06	2	105	2	12556521
Pubmed	Expression of p40 and laminin 332 in metaplastic spindle cell carcinoma of the breast compared with other malignant spindle cell tumours.	LAMC2 TP63	9.03e-06	2	105	2	25795733
Pubmed	Redox regulation of SERCA2 is required for vascular endothelial growth factor-induced signaling and endothelial cell migration.	ATP2A2 VEGFA	9.03e-06	2	105	2	22472004
Pubmed	Urothelial Carcinoma of the Bladder Induces Endothelial Cell Activation and Hypercoagulation.	VWF VEGFA	9.03e-06	2	105	2	32234826
Pubmed	Decreased c-Myc mRNA Stability via the MicroRNA 141-3p/AUF1 Axis Is Crucial for p63α Inhibition of Cyclin D1 Gene Transcription and Bladder Cancer Cell Tumorigenicity.	CCND1 TP63	9.03e-06	2	105	2	30104251
Pubmed	Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3.	MST1 MST1L	9.03e-06	2	105	2	8393443
Pubmed	Atypical fast SERCA1a protein expression in slow myofibers and differential S-nitrosylation prevented by exercise during long term bed rest.	ATP2A1 ATP2A2	9.03e-06	2	105	2	19644701
Pubmed	MSP is a negative regulator of inflammation and lipogenesis in ex vivo models of non-alcoholic steatohepatitis.	MST1 MST1L	9.03e-06	2	105	2	27609031
Pubmed	Hepatocyte growth factor-like protein is required for prostate tumor growth in the TRAMP mouse model.	MST1 MST1L	9.03e-06	2	105	2	24980820
Pubmed	Sarco(endo)plasmic reticulum Ca2+ ATPases (SERCA1 and -2) in human extraocular muscles.	ATP2A1 ATP2A2	9.03e-06	2	105	2	14638697
Pubmed	p63 and Its Target Follistatin Maintain Salivary Gland Stem/Progenitor Cell Function through TGF-β/Activin Signaling.	NDOR1 TP63	9.03e-06	2	105	2	32932139
Pubmed	Structure of the human D1F15S1A locus: a chromosome 1 locus with 97% identity to the chromosome 3 gene coding for hepatocyte growth factor-like protein.	MST1 MST1L	9.03e-06	2	105	2	10728827
Pubmed	Genetically selected Marchigian Sardinian alcohol-preferring (msP) rats: an animal model to study the neurobiology of alcoholism.	MST1 MST1L	9.03e-06	2	105	2	16961763
Pubmed	R-spondin 2 mediates neutrophil egress into the alveolar space through increased lung permeability.	NDOR1 RSPO2	9.03e-06	2	105	2	32019591
Pubmed	A common and functional gene variant in the vascular endothelial growth factor a predicts clinical outcome in early-stage breast cancer.	CCND1 VEGFA	9.03e-06	2	105	2	23625573
Pubmed	Modeling ADAMTS13-von Willebrand factor interaction: Implications for oxidative stress-related cardiovascular diseases and type 2A von Willebrand disease.	VWF ADAMTS1	9.03e-06	2	105	2	21937160
Pubmed	Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice.	MST1 MST1L	9.03e-06	2	105	2	39253972
Pubmed	Cerebral ischemia-reperfusion is modulated by macrophage-stimulating 1 through the MAPK-ERK signaling pathway.	MST1 MST1L	9.03e-06	2	105	2	32017081
Pubmed	Functional consequences of the macrophage stimulating protein 689C inflammatory bowel disease risk allele.	MST1 MST1L	9.03e-06	2	105	2	24409221
Pubmed	Co-existence of cyclin D1 and vascular endothelial growth factor protein expression is a poor prognostic factor for UICC stage I-III colorectal cancer patients after curative resection.	CCND1 VEGFA	9.03e-06	2	105	2	22926658
Pubmed	Hepatocyte-specific expression of the mouse hepatocyte growth factor-like protein.	MST1 MST1L	9.03e-06	2	105	2	8340069
Pubmed	Biological effects of targeted inactivation of hepatocyte growth factor-like protein in mice.	MST1 MST1L	9.03e-06	2	105	2	9486989
Pubmed	Treatment with XMU-MP-1 erases hyperglycaemic memory in hearts of diabetic mice.	MST1 MST1L	9.03e-06	2	105	2	33887258
Pubmed	Cigarette smoke modulates binding of the transcription factor MZF1 to the VEGF promoter and regulates VEGF expression in dependence of genetic variation SNP 405.	MZF1 VEGFA	9.03e-06	2	105	2	32449233
Pubmed	VEGFA from osteoblasts is not required for lamellar bone formation following tibial loading.	NDOR1 VEGFA	9.03e-06	2	105	2	35872107
Pubmed	HGFL supports mammary tumorigenesis by enhancing tumor cell intrinsic survival and influencing macrophage and T-cell responses.	MST1 MST1L	9.03e-06	2	105	2	25938541
Pubmed	Effect of chronic obstructive pulmonary disease on calcium pump ATPase expression in human diaphragm.	ATP2A1 ATP2A2	9.03e-06	2	105	2	15718407
Pubmed	SERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis.	ATP2A1 ATP2A2	9.03e-06	2	105	2	11402072
Pubmed	Characterization of a second human clathrin heavy chain polypeptide gene (CLH-22) from chromosome 22q11.	CLTCL1 CLTC	9.03e-06	2	105	2	8733129
Pubmed	Insight into interactions of the von-Willebrand-factor-A-like domain 2 with the FNIII-like domain 9 of collagen VII by NMR and SPR.	COL7A1 VWF	9.03e-06	2	105	2	21570975
Pubmed	Mst1 regulates post-infarction cardiac injury through the JNK-Drp1-mitochondrial fission pathway.	MST1 MST1L	9.03e-06	2	105	2	29760744
Pubmed	The effect of CCND1 +870A>G and VEGF +936C>T polymorphisms on oral cancer development and disease-free survival in a Taiwan population.	CCND1 VEGFA	9.03e-06	2	105	2	22321253
Pubmed	Cancer-associated oxidoreductase ERO1-α drives the production of VEGF via oxidative protein folding and regulating the mRNA level.	ERO1A VEGFA	9.03e-06	2	105	2	27100727
Pubmed	CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.	CLTCL1 CLTC	9.03e-06	2	105	2	29097553
Pubmed	Oxidative damage to pre-eclamptic placenta: immunohistochemical expression of VEGF, nitrotyrosine residues and von Willebrand factor.	VWF VEGFA	9.03e-06	2	105	2	22612323
Pubmed	Sarco(endo)plasmic reticulum Ca2+ ATPase isoforms and their role in muscle physiology and pathology.	ATP2A1 ATP2A2	9.03e-06	2	105	2	10603953
Pubmed	Mst1 deletion reduces hyperglycemia-mediated vascular dysfunction via attenuating mitochondrial fission and modulating the JNK signaling pathway.	MST1 MST1L	9.03e-06	2	105	2	31206688
Pubmed	Characterizing SERCA Function in Murine Skeletal Muscles after 35-37 Days of Spaceflight.	ATP2A1 ATP2A2	9.03e-06	2	105	2	34769190
Pubmed	The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step.	CLTCL1 CLTC	9.03e-06	2	105	2	20065094
Pubmed	Training induced decrease in oxygen cost of cycling is accompanied by down-regulation of SERCA expression in human vastus lateralis muscle.	ATP2A1 ATP2A2	9.03e-06	2	105	2	18953100
Pubmed	Mst1 inhibition attenuates non-alcoholic fatty liver disease via reversing Parkin-related mitophagy.	MST1 MST1L	9.03e-06	2	105	2	30708325
Pubmed	SERCA overexpression reduces hydroxyl radical injury in murine myocardium.	ATP2A1 ATP2A2	9.03e-06	2	105	2	16798816
Pubmed	Melatonin alleviates postinfarction cardiac remodeling and dysfunction by inhibiting Mst1.	MST1 MST1L	9.03e-06	2	105	2	27696525
Pubmed	Enhanced endoplasmic reticulum SERCA activity by overexpression of hepatic stimulator substance gene prevents hepatic cells from ER stress-induced apoptosis.	GFER ATP2A2	9.03e-06	2	105	2	24284796
Pubmed	Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling.	CRIM1 VEGFA	9.03e-06	2	105	2	24353059
Pubmed	Histone Demethylase JARID1B Is Overexpressed in Osteosarcoma and Upregulates Cyclin D1 Expression via Demethylation of H3K27me3.	KDM5B CCND1	9.03e-06	2	105	2	28492139
Pubmed	Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 2 isoforms and characterization of Darier disease (SERCA2) mutants by steady-state and transient kinetic analyses.	ATP2A1 ATP2A2	9.03e-06	2	105	2	12975374
Pubmed	Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos.	VWF LAMB1 VEGFA	1.18e-05	15	105	3	10706142
Pubmed	Aberrant expression of a beta-catenin gain-of-function mutant induces hyperplastic transformation in the mouse cornea.	LAMB1 TP63 VEGFA	1.46e-05	16	105	3	20332116
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	ADAMTS1 ERO1A CCND1 PLXNB2 GFER CLTC MIB1 ZNF579 ATP2A2	2.27e-05	503	105	9	36217030
Pubmed	Insulinoma-associated protein 1 controls nasopharyngeal carcinoma to radiotherapy by modulating cyclin D1-dependent DNA repair machinery.	INSM1 CCND1	2.70e-05	3	105	2	31155641
Pubmed	Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis.	VWF VEGFA	2.70e-05	3	105	2	7683699
Pubmed	Regulation of endothelial lipase and systemic HDL cholesterol levels by SREBPs and VEGF-A.	SREBF2 VEGFA	2.70e-05	3	105	2	23102786
Pubmed	Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis.	CLTCL1 CLTC	2.70e-05	3	105	2	19509056
Pubmed	The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse.	MST1 MST1L	2.70e-05	3	105	2	10225971
Pubmed	Role of COX-2, VEGF and cyclin D1 in mammary infiltrating duct carcinoma.	CCND1 VEGFA	2.70e-05	3	105	2	12883688
Pubmed	Protein kinase C-delta mediates von Willebrand factor secretion from endothelial cells in response to vascular endothelial growth factor (VEGF) but not histamine.	VWF VEGFA	2.70e-05	3	105	2	18752579
Pubmed	The Expression of Cyclin D1, VEGF, EZH2, and H3K27me3 in Atypical Teratoid/Rhabdoid Tumors of the CNS: A Possible Role in Targeted Therapy.	CCND1 VEGFA	2.70e-05	3	105	2	26469332
Pubmed	VEGFA From Early Osteoblast Lineage Cells (Osterix+) Is Required in Mice for Fracture Healing.	NDOR1 VEGFA	2.70e-05	3	105	2	31081125
Pubmed	Inhibition of MST1 ameliorates neuronal apoptosis via GSK3β/β-TrCP/NRF2 pathway in spinal cord injury accompanied by diabetes.	MST1 MST1L	2.70e-05	3	105	2	38430683
Pubmed	TRAF2 functions as an activator switch in the reactive oxygen species-induced stimulation of MST1.	MST1 MST1L	2.70e-05	3	105	2	26698664
Pubmed	Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle.	ATP2A1 ATP2A2	2.70e-05	3	105	2	27055500
Pubmed	High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis.	VWF VEGFA	2.70e-05	3	105	2	7681362
Pubmed	Zinc finger transcription factor INSM1 interrupts cyclin D1 and CDK4 binding and induces cell cycle arrest.	INSM1 CCND1	2.70e-05	3	105	2	19124461
Pubmed	Inhibition of endogenous Mst1 prevents apoptosis and cardiac dysfunction without affecting cardiac hypertrophy after myocardial infarction.	MST1 MST1L	2.70e-05	3	105	2	17395874
Pubmed	Sarcoplasmic reticulum Ca2+ ATPase pump is a major regulator of glucose transport in the healthy and diabetic heart.	ATP2A1 ATP2A2	2.70e-05	3	105	2	25615793
Pubmed	Mst1 participates in the atherosclerosis progression through macrophage autophagy inhibition and macrophage apoptosis enhancement.	MST1 MST1L	2.70e-05	3	105	2	27496379
Pubmed	ADAMTS1/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165.	ADAMTS1 VEGFA	2.70e-05	3	105	2	12716911
Pubmed	Receptor tyrosine kinase Ron is expressed in mouse reproductive tissues during embryo implantation and is important in trophoblast cell function.	MST1 MST1L	2.70e-05	3	105	2	12606483
Pubmed	Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice.	MST1 MST1L	2.70e-05	3	105	2	36623453
Pubmed	Altered mRNA splicing of the skeletal muscle ryanodine receptor and sarcoplasmic/endoplasmic reticulum Ca2+-ATPase in myotonic dystrophy type 1.	ATP2A1 ATP2A2	2.70e-05	3	105	2	15972723
Pubmed	CircRbms1 fosters MST1 mRNA and protein levels to motivate myocardial ischaemia-reperfusion injury via autophagic status.	MST1 MST1L	2.70e-05	3	105	2	38288506
Pubmed	The proto-oncogene RON is involved in development of epithelial, bone and neuro-endocrine tissues.	MST1 MST1L	2.70e-05	3	105	2	8545120
Pubmed	Hepatocyte growth factor-like protein is a positive regulator of early mammary gland ductal morphogenesis.	MST1 MST1L	2.70e-05	3	105	2	25049204
Pubmed	Characterization of the mouse cDNA and gene coding for a hepatocyte growth factor-like protein: expression during development.	MST1 MST1L	2.70e-05	3	105	2	1832957
Pubmed	Activation of pro-survival CaMK4β/CREB and pro-death MST1 signaling at early and late times during a mouse model of prion disease.	MST1 MST1L	2.70e-05	3	105	2	25183307
Pubmed	Osmotic and hypoxic induction of the complement factor C9 in cultured human retinal pigment epithelial cells: Regulation of VEGF and NLRP3 expression.	C9 VEGFA	2.70e-05	3	105	2	30090015
Pubmed	MST1 mediates neuronal loss and cognitive deficits: A novel therapeutic target for Alzheimer's disease.	MST1 MST1L	2.70e-05	3	105	2	35525373
Pubmed	MST1 coordinately regulates autophagy and apoptosis in diabetic cardiomyopathy in mice.	MST1 MST1L	2.70e-05	3	105	2	27510910
Pubmed	Relevance of brain natriuretic peptide in preload-dependent regulation of cardiac sarcoplasmic reticulum Ca2+ ATPase expression.	ATP2A1 ATP2A2	2.70e-05	3	105	2	16754798
Pubmed	Heparins that block VEGF-A-mediated von Willebrand factor fiber generation are potent inhibitors of hematogenous but not lymphatic metastasis.	VWF VEGFA	2.70e-05	3	105	2	27602496
Pubmed	Found in inflammatory zone 1 induces angiogenesis in murine models of asthma.	VWF VEGFA	2.70e-05	3	105	2	18758859
Pubmed	RNA N6-methyladenosine reader IGF2BP3 regulates cell cycle and angiogenesis in colon cancer.	CCND1 VEGFA	2.70e-05	3	105	2	32993738
Pubmed	Hippo kinases Mst1 and Mst2 maintain NK cell homeostasis by orchestrating metabolic state and transcriptional activity.	MST1 MST1L	2.70e-05	3	105	2	38898027
Pubmed	WASP and Mst1 coregulate B-cell development and B-cell receptor signaling.	MST1 MST1L	2.70e-05	3	105	2	32045478
Pubmed	Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2.	MST1 MST1L	2.70e-05	3	105	2	27940445
Pubmed	The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family.	ADAMTS2 ADAMTS1	2.70e-05	3	105	2	26025392
Pubmed	Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of Ca(V)1.1 calcium channel.	MBNL1 ATP2A1	2.70e-05	3	105	2	22140091
Pubmed	CircPLXNB2 regulates acute myeloid leukemia progression through miR-654-3p/CCND1 axis.	CCND1 PLXNB2	2.70e-05	3	105	2	37272581
Pubmed	Macrophage stimulating protein is a target-derived neurotrophic factor for developing sensory and sympathetic neurons.	MST1 MST1L	2.70e-05	3	105	2	12538524
Cytoband	19p13.1	AKAP8 COMP WIZ	1.87e-04	48	105	3	19p13.1
Cytoband	16p12.1	ATP2A1 LCMT1	1.50e-03	25	105	2	16p12.1
Cytoband	8q24	TG C8orf82	1.88e-03	28	105	2	8q24
Cytoband	3p21	MST1 TMIE	2.61e-03	33	105	2	3p21
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF559 ZNF696 PRDM5 ZBTB7B ZNF623 ZNF800 WIZ ZNF732 MZF1 ZNF579 ZFP62 ZNF541 ZNF646	7.15e-06	718	75	13	28
GeneFamily	ATPases Ca2+ transporting	ATP2A1 ATP2A2	6.00e-04	9	75	2	1209
GeneFamily	Plexins	PLXNB2 PLXNA1	6.00e-04	9	75	2	683
GeneFamily	Laminin subunits	LAMB1 LAMC2	1.09e-03	12	75	2	626
GeneFamily	CD molecules\|Gamma-glutamyltransferases	GGT1 GGT3P	1.29e-03	13	75	2	564
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM5 PRDM8	2.22e-03	17	75	2	1197
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS2 ADAMTS1	2.77e-03	19	75	2	50
Coexpression	NABA_MATRISOME	COL7A1 VWF COMP CRIM1 ADAMTS2 ADAMTS1 NRG2 LAMB1 LAMC2 COL25A1 SMOC2 PLXNB2 MST1 SEMA5B CLEC14A SBSPON RSPO2 VWA3B MST1L PLXNA1 OTOG VEGFA	6.92e-11	1008	105	22	MM17056
Coexpression	NABA_MATRISOME	COL7A1 VWF COMP CRIM1 ADAMTS2 ADAMTS1 NRG2 LAMB1 LAMC2 COL25A1 SMOC2 PLXNB2 MST1 SEMA5B CLEC14A SBSPON RSPO2 VWA3B MST1L PLXNA1 OTOG VEGFA	9.70e-11	1026	105	22	M5889
Coexpression	NABA_CORE_MATRISOME	COL7A1 VWF COMP CRIM1 LAMB1 LAMC2 COL25A1 SMOC2 SBSPON RSPO2 VWA3B OTOG	9.33e-10	270	105	12	MM17057
Coexpression	NABA_CORE_MATRISOME	COL7A1 VWF COMP CRIM1 LAMB1 LAMC2 COL25A1 SMOC2 SBSPON RSPO2 VWA3B OTOG	1.15e-09	275	105	12	M5884
Coexpression	NABA_ECM_GLYCOPROTEINS	VWF COMP CRIM1 LAMB1 LAMC2 SMOC2 SBSPON RSPO2 VWA3B OTOG	5.28e-09	191	105	10	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	VWF COMP CRIM1 LAMB1 LAMC2 SMOC2 SBSPON RSPO2 VWA3B OTOG	6.77e-09	196	105	10	M3008
Coexpression	KOBAYASHI_EGFR_SIGNALING_6HR_DN	DUSP5 CCND1 VEGFA	4.88e-05	18	105	3	M659
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU4 CCND1 TAFA4 OPRL1 SEMA5B DLL3 ACAP3	3.44e-07	190	105	7	9b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU4 CCND1 TAFA4 OPRL1 SEMA5B DLL3 ACAP3	3.44e-07	190	105	7	d146af1926474328a7c822bc140c4dda66e1bbfb
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL7A1 NRG2 LAMB1 LAMC2 SMOC2 TP63 ATP2A2	4.24e-07	196	105	7	a58bdf9de05d13d84211e09a933679d485bf8ab4
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	LMNTD2 LAMC2 CCND1 ARHGEF1 BAIAP2 PLXNA1 VEGFA	4.70e-07	199	105	7	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	LMNTD2 LAMC2 CCND1 PLXNB2 BAIAP2 PLXNA1 VEGFA	4.86e-07	200	105	7	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	LAMC2 CCND1 SBSPON ARHGEF1 BAIAP2 PLXNA1 VEGFA	4.86e-07	200	105	7	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GPR26 DUSP5 CHN1 ADRB1 ZMYND10 BAIAP2	2.30e-06	161	105	6	ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GPR26 DUSP5 CHN1 ADRB1 ZMYND10 BAIAP2	3.72e-06	175	105	6	ff0789f5913c9f3c49159e40b1ec3d2ff175ec9f
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GPR26 DUSP5 CHN1 ADRB1 ZMYND10 BAIAP2	3.72e-06	175	105	6	21f8f11a8b874d4f7c47931010a2535f2a5a3373
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF CRIM1 ADAMTS1 COL25A1 CLEC14A ZNF541	4.23e-06	179	105	6	d2db9e70b780643f1e004c41a70464d0abe26088
ToppCell	Basal\|World / shred by cell class for mouse tongue	COL7A1 CRIM1 LAMB1 LAMC2 CCND1 TP63	4.81e-06	183	105	6	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|343B / Donor, Lineage, Cell class and subclass (all cells)	LAMC2 CCND1 GGT1 SBSPON PLXNA1 VEGFA	4.96e-06	184	105	6	cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	LAMC2 CCND1 GGT1 SBSPON PLXNA1 VEGFA	4.96e-06	184	105	6	bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	VWF CRIM1 ADAMTS1 DUSP5 CHN1 CLEC14A	5.12e-06	185	105	6	a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU4 CCND1 TAFA4 OPRL1 SEMA5B DLL3	5.61e-06	188	105	6	7471c194276161422326647f09022e94f3d1640c
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU4 CCND1 OPRL1 SEMA5B DLL3 ACAP3	5.61e-06	188	105	6	a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU4 CCND1 TAFA4 OPRL1 SEMA5B DLL3	5.61e-06	188	105	6	053c251d3ddbeb866f34565aefca4535517b4387
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU4 CCND1 OPRL1 SEMA5B DLL3 ACAP3	5.61e-06	188	105	6	c8530c9ff98666c64a94683261af4288cb790a7e
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CRIM1 DUSP5 LAMB1 MAP1LC3A CHN1 SEMA5B	5.96e-06	190	105	6	106862ef44fcaa0971c3ba0147d13eb08015ca77
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU4 CCND1 TAFA4 OPRL1 SEMA5B DLL3	6.14e-06	191	105	6	ece87127f85939e61b1048d968ed96f0e87c3a79
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU4 CCND1 TAFA4 OPRL1 SEMA5B DLL3	6.14e-06	191	105	6	478e8341ee03b05501e2233e02cef5f97492c95d
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSM1 PLXNB2 CLTC SEC16A ATP2A2 BAIAP3	6.52e-06	193	105	6	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSM1 PLXNB2 CLTC SEC16A ATP2A2 BAIAP3	6.52e-06	193	105	6	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	21-Trachea-Mesenchymal\|Trachea / Age, Tissue, Lineage and Cell class	ADAMTS2 ADAMTS1 GFRA2 IGDCC4 SBSPON RSPO2	6.72e-06	194	105	6	749dd8113ef260e00facac09de9861d61725124a
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)\|356C / Donor, Lineage, Cell class and subclass (all cells)	LAMC2 CCND1 GGT1 SBSPON PLXNA1 VEGFA	6.92e-06	195	105	6	07a3ef6b0f1201fe2bcb9ea426b8f7a69beb4904
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	LAMC2 CCND1 GGT1 SBSPON PLXNA1 VEGFA	6.92e-06	195	105	6	b65511770ed67f7447847e2187555b362988af45
ToppCell	facs-Bladder-nan-3m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS2 MBNL1 LAMB1 GANAB MRPS21 CLTC	7.12e-06	196	105	6	44f5b1b474399c9316729155f2ea95a82ca66e30
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADAMTS1 PLXNB2 BAIAP2 PLXNA1 ACAP3 VEGFA	7.12e-06	196	105	6	b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell	(7)_Epithelial-I_(AT1)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	LAMC2 CCND1 GGT1 SBSPON PLXNA1 VEGFA	7.12e-06	196	105	6	150554fa06868d29b0608189862eef6505ba757f
ToppCell	facs-Bladder-nan-3m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS2 MBNL1 LAMB1 GANAB MRPS21 CLTC	7.12e-06	196	105	6	c0e90d964baa2eb4fbd18a52379ccec5d3bf59a8
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAMTS2 ADAMTS1 LAMB1 COL25A1 SMOC2 GFRA2	7.33e-06	197	105	6	06a0d7062dadda656decaf77dcef9a10b5f2698d
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAMTS2 ADAMTS1 LAMB1 COL25A1 SMOC2 GFRA2	7.33e-06	197	105	6	d35c7a36135b5ed6a7bf2f934849678eba2a0177
ToppCell	Parenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CLTCL1 ADAMTS1 COL25A1 SMOC2 CHN1 SEMA5B	7.55e-06	198	105	6	882710bd6215e299257dd3df234292db9a2823ba
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	LAMC2 CCND1 GGT1 SBSPON PLXNA1 VEGFA	7.77e-06	199	105	6	5a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	LAMC2 CCND1 SBSPON ARHGEF1 BAIAP2 VEGFA	7.77e-06	199	105	6	1c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CRIM1 ADAMTS1 LAMB1 ANKRD50 CHN1 GFRA2	7.99e-06	200	105	6	4e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LAMC2 CCND1 GGT1 SBSPON PLXNA1 VEGFA	7.99e-06	200	105	6	c6f211bbadd0c9be776c58807249e06764df47dc
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	LMNTD2 LAMC2 CCND1 ARHGEF1 BAIAP2 VEGFA	7.99e-06	200	105	6	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	distal-Hematologic-EREG+_Dendritic-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NEU4 FOLR2 COL25A1 GFRA2 ATP2A2 VEGFA	7.99e-06	200	105	6	7809c74a2e52768854b66a135522138281bc4449
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	LAMC2 CCND1 GGT1 SBSPON PLXNA1 VEGFA	7.99e-06	200	105	6	5f7e8d8b05c90a10313775f9f126eb4ab0fe4f67
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-AT1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	LAMC2 CCND1 GGT1 SBSPON PLXNA1 VEGFA	7.99e-06	200	105	6	e3a80626941363bfc9d97ef906d38c97080aecb1
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2\|Control_saline / Treatment groups by lineage, cell group, cell type	CRIM1 LAMB1 ANKRD50 CHN1 PLXNB2 GFRA2	7.99e-06	200	105	6	bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell	Tracheal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_systemic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	NDOR1 COL25A1 CHN1 ATP2A1	2.41e-05	71	105	4	5d63a582229520b2a037f3c27f772e34cdee092b
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GPR26 DUSP5 CHN1 RSPO2 BAIAP2	2.58e-05	147	105	5	8f725ff8fb4ced5db2643e80669d3f7945b820ab
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SLFN12 LMNTD2 TG ATP2A1	3.00e-05	75	105	4	3167beedef7304697e9577270cdeacfc9743cee1
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SLFN12 LMNTD2 TG ATP2A1	3.00e-05	75	105	4	70c346f92a9ac7e33fc1b9dee1dca0bf9ae0a38c
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SLFN12 LMNTD2 TG ATP2A1	3.00e-05	75	105	4	26d6e54ed0a6c3ff57f6269c460177bc7b8bf979
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF559 CHN1 MIB1 ZNF579 BAIAP3	3.43e-05	156	105	5	14e2f693a75f1075f40cc7b16ee430262a5de016
ToppCell	10x5'-blood-Lymphocytic_T_CD4-Trm_Th1/Th17\|blood / Manually curated celltypes from each tissue	TCF19 CRIM1 DUSP5 NRG2 CHN1	3.54e-05	157	105	5	c99cb26d831c25038f2aa1b1c0f7ba52facb2e7a
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TCF19 GPR26 LAMC2 GFRA2 PRDM8	3.65e-05	158	105	5	c8af8964a140acb2987e3b4906d72c546108d229
ToppCell	droplet-Thymus-nan-21m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF FOLR2 CCND1 GFRA2 ATP2A1	3.99e-05	161	105	5	441ebd3c029861d833fbcf8a68fc740d9de8ef2f
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-1\|TCGA-Kidney / Sample_Type by Project: Shred V9	VWF CCND1 COL25A1 CLEC14A VEGFA	3.99e-05	161	105	5	6cacae4a759ace763597ee394cff498dc5d96f74
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COMP CRIM1 COL25A1 TMIE C9	4.75e-05	167	105	5	102b3d160a44c8623fab1fd10e9054178c42a78b
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4\|TCGA-Lung / Sample_Type by Project: Shred V9	ADAMTS2 LAMB1 CHN1 IGDCC4 FHL3	4.88e-05	168	105	5	aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU4 VWF CRIM1 ADAMTS1 CLEC14A	5.02e-05	169	105	5	8dba7546adc6b1345933eec81fc77fc9611fae60
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCF19 ADAMTS2 SMOC2 CACNA1G PLXNA1	5.02e-05	169	105	5	335619507857383c3b0b507cdf05d786ed59e585
ToppCell	facs-Lung-Endomucin-24m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU4 VWF CRIM1 ADAMTS1 CLEC14A	5.02e-05	169	105	5	d2862a7ddee6d7a65d84ef9d0800ba6f4690973f
ToppCell	droplet-Marrow-nan-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLFN12 KANSL3 FSCN2 CACNA1G TOR1B	5.02e-05	169	105	5	5f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CRIM1 DUSP5 LAMB1 CHN1 SEMA5B	5.17e-05	170	105	5	1f994b690e881106a5d54b3080ccce6260bc3ac5
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERO1A NRG2 TAFA4 LCMT1 VEGFA	5.31e-05	171	105	5	fea6ef6bbfebea2dd0f0360c7db7a5e858f15958
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERO1A NRG2 TAFA4 LCMT1 VEGFA	5.31e-05	171	105	5	f15594fd4d709920733de9376a391dedc62b65de
ToppCell	Adult-Mesenchymal-pericyte_cell-D231\|Adult / Lineage, Cell type, age group and donor	CRIM1 LAMB1 CHN1 DNAJC14 SEMA5B	5.46e-05	172	105	5	858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCell	ASK440-Epithelial-Transformed_epithelium\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	COL7A1 LAMB1 SMOC2 CHN1 ZNF623	5.46e-05	172	105	5	df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS2 CHN1 OPRL1 WIZ FSCN2	5.61e-05	173	105	5	176d7dc103b8161c4e2d7dc74f2dc77ea1f2d2ed
ToppCell	AT1_cells-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	ZNF696 LAMC2 ADRB1 PLXNA1 VEGFA	5.61e-05	173	105	5	b29816427428c7053017477f59b828bf1357f3b2
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|390C / Donor, Lineage, Cell class and subclass (all cells)	COMP LAMB1 PRDM5 CHN1 CACNA1G	6.09e-05	176	105	5	852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell	AT1_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	LAMC2 GGT1 SBSPON PLXNA1 VEGFA	6.09e-05	176	105	5	458720776b0151cd55acc352d509599cb62f0ca8
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	COMP LAMB1 PRDM5 CHN1 CACNA1G	6.09e-05	176	105	5	d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCell	facs-Brain_Myeloid-Striatum\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAGAP MBNL1 ADRB1 CLTC FHL3	6.26e-05	177	105	5	efb1990fd1d216f64261e81017299783afb24a1e
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-macrophage\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOLR2 CCND1 PLXNB2 GFRA2 PLXNA1	6.43e-05	178	105	5	6c1b5087581ca8cea976d89ea6f34088c8fc3668
ToppCell	facs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF CRIM1 ADAMTS1 CLEC14A DLL3	6.43e-05	178	105	5	ebfae386a518ea33911ba3ff40464c94d18ef695
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS2 ADAMTS1 LAMB1 COL25A1 SMOC2	6.43e-05	178	105	5	d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCell	facs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF CRIM1 ADAMTS1 CLEC14A DLL3	6.43e-05	178	105	5	ccd37575b60102f5e647c01546e8ff8fec638bd7
ToppCell	facs-Lung-18m-Endothelial-venous_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF CRIM1 ADAMTS1 CLEC14A DLL3	6.43e-05	178	105	5	87b04753650e45f12299c8456fb980d6c0d5961c
ToppCell	facs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY9 OPRL1 SEMA5B SBSPON CACNA1G	6.77e-05	180	105	5	a37cc885fe3f6cb9df69d43358064c83c18412e7
ToppCell	facs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY9 OPRL1 SEMA5B SBSPON CACNA1G	6.77e-05	180	105	5	63a6d532b16b8b15c7c9102148d7297ee3afd641
ToppCell	Neuroendocrine-neuroendo-1\|World / Class top	VWF INSM1 SMOC2 TG DLL3	6.77e-05	180	105	5	50fdd182a083380899b5943cb5f55ffd77e2a7d4
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL7A1 ADAMTS2 LAMB1 SMOC2 CACNA1G	6.95e-05	181	105	5	3462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL7A1 ADAMTS2 LAMB1 SMOC2 CACNA1G	6.95e-05	181	105	5	6730e249cac55ae892cc567d9211615882f3dab4
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ADAMTS1 NRG2 SMOC2 SBSPON VEGFA	7.32e-05	183	105	5	a1d4f25e13f5b9e92a9ca0a804a7bed5df8fb2fe
ToppCell	tumor_Lung-Fibroblasts-Pericytes\|tumor_Lung / Location, Cell class and cell subclass	ADAMTS1 LAMB1 SMOC2 CHN1 SEMA5B	7.32e-05	183	105	5	a03dd563af9b15cb1f5de5732a229405a9f82d84
ToppCell	Adult-Mesenchymal-pericyte_cell-D122\|Adult / Lineage, Cell type, age group and donor	COL7A1 CRIM1 LAMB1 TAFA4 CHN1	7.32e-05	183	105	5	fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	VWF TCF19 ANKRD50 CHN1 SEMA5B	7.51e-05	184	105	5	688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	LAMC2 CCND1 GGT1 SBSPON PLXNA1	7.51e-05	184	105	5	c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU4 CCND1 TAFA4 SEMA5B DLL3	7.51e-05	184	105	5	278a7ed764c326450cb70e69ed2175980eaf5fe0
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	LAMC2 CCND1 GGT1 SBSPON PLXNA1	7.51e-05	184	105	5	1ed558a88215b248431c524ea16f13d9022ae98c
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU4 CCND1 TAFA4 SEMA5B DLL3	7.51e-05	184	105	5	8d86e125257ff1d3af8d90577a8b3f0321eca21c
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CRIM1 ADAMTS1 LAMB1 CHN1 GFRA2	7.51e-05	184	105	5	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEKHF1 MAP1LC3A CCND1 ADRB1 CLEC14A	7.71e-05	185	105	5	9f6c1e35047d1618974b802a1d609c1f4b99ce84
ToppCell	COVID-19-Fibroblasts-Pericytes\|COVID-19 / group, cell type (main and fine annotations)	CRIM1 ADAMTS1 LAMB1 COL25A1 CHN1	7.71e-05	185	105	5	4905adaeeffd353e089578e5ea614437dbe794e6
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEKHF1 MAP1LC3A CCND1 ADRB1 CLEC14A	7.71e-05	185	105	5	a82a0252ae091ee8fcb453ae03ba21542b220e8f
ToppCell	TCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell\|TCGA-Uvea / Sample_Type by Project: Shred V9	MYO19 DUSP5 LAMB1 TOR1B ATP2A2	7.91e-05	186	105	5	e8580a2093eb7e50aad55ec7fada850d2fed8ae1
ToppCell	Adult-Endothelial-endothelial_cell_of_artery\|Adult / Lineage, Cell type, age group and donor	VWF ADAMTS1 DUSP5 CHN1 CLEC14A	7.91e-05	186	105	5	2d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	INSM1 CCND1 COL25A1 DLL3 ACAP3	8.11e-05	187	105	5	dfc2b95d70daf533bc0cc4ce78af9f65dd75a25b
ToppCell	Adult-Mesenchymal-pericyte_cell\|Adult / Lineage, Cell type, age group and donor	COL7A1 CRIM1 LAMB1 TAFA4 CHN1	8.11e-05	187	105	5	62759efb660179402fb574ce5701c89a2e17bcfe
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ADAMTS1 ADRB1 CLEC14A VEGFA	8.11e-05	187	105	5	52ffd4be374e329ac8d321063f061b826d252956
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma\|TCGA-Kidney / Sample_Type by Project: Shred V9	VWF CCND1 SEMA5B CLEC14A VEGFA	8.32e-05	188	105	5	e711c7a46d7cfa030ca2982eacc1dae5af5788dd
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU4 CCND1 TAFA4 SEMA5B DLL3	8.32e-05	188	105	5	006db2c2c44971ca9241c582bc89f258c785f5ed
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CRIM1 DUSP5 LAMB1 CHN1 ADCY9	8.32e-05	188	105	5	a906c29e3fda22eecfec3e5cac706c417bf2b7a4
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEU4 CCND1 TAFA4 SEMA5B DLL3	8.32e-05	188	105	5	d0e6fb4a3b3d79d3512b5500062ea285495ae526
Drug	PE-W	CLTCL1 TG CLTC ATP2A1	7.17e-07	16	104	4	CID016040251
Drug	AC1L1IPS	CLTCL1 TG CLTC	1.83e-06	6	104	3	CID000004682
Drug	perillyl alcohol	ADAMTS2 SREBF2 CCND1 M6PR VEGFA	5.73e-06	56	104	5	CID000010819
Drug	NSC-343257	NEU4 CLTCL1 ADAMTS1 FOLR2 TG CLTC M6PR VEGFA	1.01e-05	228	104	8	CID000004242
Drug	(2s,5s)-5-Carboxymethylproline	COL7A1 VWF MBNL1 COL25A1 TG DLL3 CRYZL1 PLXNA1 VEGFA	1.40e-05	314	104	9	CID000447989
Disease	Brody myopathy (implicated_via_orthology)	ATP2A1 ATP2A2	3.54e-05	3	102	2	DOID:0050692 (implicated_via_orthology)
Disease	Congestive heart failure	VWF ADRB1 ATP2A1 ATP2A2 VEGFA	4.10e-05	110	102	5	C0018802
Disease	Heart failure	VWF ADRB1 ATP2A1 ATP2A2 VEGFA	4.10e-05	110	102	5	C0018801
Disease	Left-Sided Heart Failure	VWF ADRB1 ATP2A1 ATP2A2 VEGFA	4.10e-05	110	102	5	C0023212
Disease	Heart Failure, Right-Sided	VWF ADRB1 ATP2A1 ATP2A2 VEGFA	4.10e-05	110	102	5	C0235527
Disease	Heart Decompensation	VWF ADRB1 ATP2A1 ATP2A2 VEGFA	4.10e-05	110	102	5	C1961112
Disease	Myocardial Failure	VWF ADRB1 ATP2A1 ATP2A2 VEGFA	4.10e-05	110	102	5	C1959583
Disease	Duane Retraction Syndrome	COL25A1 CHN1	1.18e-04	5	102	2	C0013261
Disease	cervical cancer	CCND1 TP63 VEGFA	2.22e-04	34	102	3	C4048328
Disease	Malignant tumor of colon	KDM5B TCF19 CCND1 TP63 VEGFA	2.33e-04	159	102	5	C0007102
Disease	aflatoxins-related hepatocellular carcinoma (biomarker_via_orthology)	GGT1 GGT3P	2.46e-04	7	102	2	DOID:5022 (biomarker_via_orthology)
Disease	Disease Exacerbation	COL7A1 SREBF2 LAMC2 CCND1 M6PR	2.77e-04	165	102	5	C0235874
Disease	Urologic Neoplasms	CCND1 VEGFA	3.27e-04	8	102	2	C0042076
Disease	alcohol dependence (biomarker_via_orthology)	GGT1 GGT3P	3.27e-04	8	102	2	DOID:0050741 (biomarker_via_orthology)
Disease	Cancer of Urinary Tract	CCND1 VEGFA	3.27e-04	8	102	2	C0751571
Disease	Malignant neoplasm of breast	COL7A1 VWF AKAP8 ADAMTS1 FOLR2 SREBF2 CCND1 TAFA4 MST1 SEMA5B ZNF541 ZNF646	3.38e-04	1074	102	12	C0006142
Disease	cervix uteri carcinoma in situ (is_marker_for)	CCND1 TP63 VEGFA	4.17e-04	42	102	3	DOID:8991 (is_marker_for)
Disease	uveal melanoma (is_marker_for)	KDM5B VEGFA	4.19e-04	9	102	2	DOID:6039 (is_marker_for)
Disease	urinary bladder cancer (is_marker_for)	KDM5B CCND1 TP63 VEGFA	5.29e-04	107	102	4	DOID:11054 (is_marker_for)
Disease	taurodeoxycholate measurement	MBNL1 SMOC2	7.64e-04	12	102	2	EFO_0010539
Disease	diabetic retinopathy (is_marker_for)	VWF GGT1 VEGFA	8.75e-04	54	102	3	DOID:8947 (is_marker_for)
Disease	gamma-glutamylleucine measurement	MBNL1 GGT1	9.00e-04	13	102	2	EFO_0021140
Disease	intracranial aneurysm (is_marker_for)	VWF VEGFA	1.05e-03	14	102	2	DOID:10941 (is_marker_for)
Disease	Spondyloepiphyseal Dysplasia	DLL3 VEGFA	1.38e-03	16	102	2	C0038015
Disease	Spondyloepiphyseal Dysplasia Tarda, X-Linked	DLL3 VEGFA	1.38e-03	16	102	2	C3541456
Disease	Schwartz-Jampel Syndrome, Type 1	DLL3 VEGFA	1.38e-03	16	102	2	C4551479
Disease	Schwartz-Jampel Syndrome	DLL3 VEGFA	1.38e-03	16	102	2	C0036391
Disease	Melnick-Needles Syndrome	DLL3 VEGFA	1.38e-03	16	102	2	C0025237
Disease	Van Buchem disease	DLL3 VEGFA	1.56e-03	17	102	2	C0432272
Disease	Hemangiosarcoma	CCND1 VEGFA	1.75e-03	18	102	2	C0018923
Disease	Colonic Neoplasms	KDM5B TCF19 CCND1 VEGFA	1.94e-03	152	102	4	C0009375
Disease	Osteochondrodysplasias	DLL3 VEGFA	1.95e-03	19	102	2	C0029422
Disease	Dyschondroplasias	DLL3 VEGFA	1.95e-03	19	102	2	C0013366
Disease	type 1 diabetes mellitus (biomarker_via_orthology)	VWF ADRB1	1.95e-03	19	102	2	DOID:9744 (biomarker_via_orthology)
Disease	Non-Small Cell Lung Carcinoma	COL7A1 ADAMTS1 LAMC2 VEGFA	2.14e-03	156	102	4	C0007131
Disease	Multiple Epiphyseal Dysplasia	DLL3 VEGFA	2.16e-03	20	102	2	C0026760
Disease	gastric ulcer	GGT1 ZNF800	2.38e-03	21	102	2	EFO_0009454
Disease	leptin measurement	SMOC2 ZNF800 TP63	2.81e-03	81	102	3	EFO_0005000
Disease	liver cirrhosis (is_marker_for)	MAP1LC3A GGT1 VEGFA	2.91e-03	82	102	3	DOID:5082 (is_marker_for)
Disease	Myocardial Reperfusion Injury	ADRB1 ATP2A2 VEGFA	3.23e-03	85	102	3	C0027055
Disease	Depressive disorder	TG ADRB1 ATP2A2 M6PR VEGFA	3.35e-03	289	102	5	C0011581
Disease	inflammatory bowel disease (implicated_via_orthology)	MST1 MST1L	3.37e-03	25	102	2	DOID:0050589 (implicated_via_orthology)
Disease	Cancer of Neck	TP63 VEGFA	3.37e-03	25	102	2	C0746787

Protein segments in the cluster

Peptide	Gene	Start	Entry
QAECVRCPRDSNRCK	nan	126	Q6ZRU5
PDFRKAFQRLLCCAR	ADRB1	381	P08588
LFSECVNQCDIRRRP	DIAPH2-AS1	106	Q14236
FCAFVQEAESRPRCR	ARHGEF1	536	Q92888
SPCGRERNFLRCEDR	C8orf82	96	Q6P1X6
SVPAEACRRRAACVL	BAIAP3	1086	O94812
RDRAADRIQFACSVC	AKAP8	381	O43823
RCPERQCRKDNCVTV	COMP	281	P49747
RLCSVKPCEDIERRF	ACAP3	316	Q96P50
RFLSRVIKCDPDCLR	CCND1	231	P24385
CERNPAEAFKRCVLL	ANKRD50	161	Q9ULJ7
EKRVDRCSLQPCRNG	DLL3	351	Q9NYJ7
RRACCFARVEPSHKS	ATP2A1	671	O14983
DARPESRRACSRELC	ADAMTS2	961	O95450
VCRANKPRTRDFATA	IGDCC4	311	Q8TDY8
ACSLEDKQCLERFRP	CRYZL1	176	O95825
KRVRYRSCNLEDCPD	ADAMTS1	601	Q9UHI8
ERPFQCEECKALFRT	PRDM5	401	Q9NQX1
EQQPVLCEVFCRDRK	GGT3P	186	A6NGU5
REPKSARYCAECNRL	DNAJC14	551	Q6Y2X3
QIRRCTDDVRPQDCY	MST1L	341	Q2TV78
QVFRKPCARAECDTR	MYO19	361	Q96H55
CTLCSRRPDERLRFA	GPR26	156	Q8NDV2
CSRRDACERADEPQR	PLXNA1	541	Q9UIW2
VEGRCTRKAECPRAE	PLXNB2	491	O15031
AKIRIAREAPSECNC	COL25A1	106	Q9BXS0
KCNSPACVEARARRA	NRG2	546	O14511
ERDIRDPNFCERCTC	LAMB1	386	P07942
RECKSSDCRRRNSRP	FLVCR1-DT	61	Q8TAF5
VRPSSEKNDCCRGKR	KDM5B	1386	Q9UGL1
RVCRKSVDRSCPLVA	LMNTD2	591	Q8IXW0
VDRRECFGKICRTSP	NEU4	181	Q8WWR8
CNRPRRTILEVLCDF	NDOR1	346	Q9UHB4
KCVQCRAVVERRVPF	MIB1	896	Q86YT6
EARICACPGRDRKAD	TP63	341	Q9H3D4
RDACLNARCFARVEP	ATP2A2	666	P16615
FRCCRCQRSLADEPF	FHL3	66	Q13643
FRPCEDIACDSQRCR	CACNA1G	101	O43497
NREISPTERCNRRKC	GFRA2	186	O00451
KARCEVQFSPRCPED	CRIM1	176	Q9NZV1
ERFLDVPLCKEDCQR	FOLR2	121	P14207
EEACLERCFPQTQRR	ADCY9	101	O60503
RRDCAVKPCQSDEVP	ERO1A	96	Q96HE7
RADSPRCRKASVVFN	IFNL4	146	K9M1U5
LEVCREFQRGTCSRP	MBNL1	16	Q9NR56
CNEPVLRRVAVDKCA	KANSL3	161	Q9P2N6
LPAARATSRREVCDC	LAMC2	16	Q13753
ANRFGTREACERRCP	COL7A1	2916	Q02388
YQIRRCTDDVRPQDC	MST1	356	P26927
RRITCTCEVENRPKY	CHN1	31	P15882
RKEAAARCVVLDCRP	DUSP5	16	Q16690
KRCTDAVGDRRQCVP	C9	76	P02748
KCSRIVRVEYRCPEC	INSM1	286	Q01101
FQTCRDPRAASCRDV	OTOG	1421	Q6ZRI0
RKFCCASALRRDVQV	OPRL1	331	P41146
RRCPKIREECEFQER	EPPIN	31	O95925
RVACEAEQPGRDCRF	FSCN2	76	O14926
VVCAECSRQRFLLPR	PLEKHF1	181	Q96S99
RIEERSQTVKCSCFP	TAFA4	66	Q96LR4
RDCLVRRCSQPVFEA	TAGAP	706	Q8N103
RRRQCDLAGVETCKS	LCMT1	246	Q9UIC8
ISRFACRIVCDRNEP	PELI2	136	Q9HAT8
CRIVCDRNEPYTARI	PELI2	141	Q9HAT8
CEESSFCKRQRSIRP	GANAB	41	Q14697
RREEKLKCPICNESF	PRDM8	661	Q9NQV8
DEGREARLQCPKCVF	WIZ	346	O95785
PFKQRRSFADRCKEV	MAP1LC3A	6	Q9H492
RAPDMNRCARCRIEN	RSPO2	86	Q6UXX9
RRRFCFLVEKQCAVA	BAIAP2	191	Q9UQB8
VAEDASRRRPCRACV	GFER	61	P55789
RICRESNCYDPERVK	CLTC	746	Q00610
RICRESSCYNPERVK	CLTCL1	746	P53675
VEEPQRSCTARRCAV	CLEC14A	131	Q86T13
IQAAREADFRCPGCR	TCF19	326	Q9Y242
CLNRDPARVVVVDCK	TIMM50	236	Q3ZCQ8
SENAPVCDRCRQKTR	USP21	431	Q9UK80
EKPFACEVCGVRFTR	ZBTB7B	371	O15156
PNFTCACRKEECKRV	VWF	2356	P04275
VADGCDFVCRSKPRN	M6PR	236	P20645
RQFENRIVKSCPQCR	MKRN3	351	Q13064
CADQCKPTTRVRRRS	SBSPON	86	Q8IVN8
RETCVRQKQCRPAAA	SEC16A	636	O15027
EKPCCRRQRESYERC	MRPS21	46	P82921
RGNCKDVSRCVAERK	SMOC2	81	Q9H3U7
CVFNCRVPRTRKEIE	TMIE	76	Q8NEW7
RTLEKVGDRRSCNDC	SREBF2	1111	Q12772
EKPFRCTECGRAFRL	ZNF696	346	Q9H7X3
EDKERPFRCTQCGRS	ZNF646	1671	O15015
RVERFCCAVFAKEPD	SLFN12	306	Q8IYM2
NEIKSRDPIRCRECG	POLR2K	26	P53803
RICVGKSREERFCNE	SEMA5B	701	Q9P283
RRVHTREKPYECDRC	ZFP62	636	Q8NB50
CPLCTYETRRKRDVI	ZNF800	521	Q2TB10
RPRCAYCSAEASKRC	ZMYND10	391	O75800
CNNRREFCPRSALIK	VWA3B	1136	Q502W6
PVNDDLCFSRKRVSR	TOGARAM1	701	Q9Y4F4
EVPICRDFLKGDCQR	ZC3H10	136	Q96K80
RCEECGKAFRRSRVL	ZNF732	531	B4DXR9
RQLELNERTCRCDKP	VEGFA	216	P15692
ERPFECNECGKAFIR	ZNF623	316	O75123
RPFECQECGKAFTRS	ZNF559	491	Q9BR84
PFQCVRCQREFKRLA	ZNF579	411	Q8NAF0
ISGRFRCPTKCEVER	TG	291	P01266
CRFAECCREERPLNA	TOR1B	51	O14657
ARDQRAPRKCCEAVL	nan	116	Q6ZVH6
QGIFPCRECERVFDK	ZNF541	1286	Q9H0D2
EQQPVLCEVFCRDRK	GGT1	186	P19440
PCSECRESFARRAVL	MZF1	486	P28698