Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF134 ZBTB38 ZNF143 ZNF672 TBX4 ZNF354A ZNF658 ZNF391 ZFP30 ZBTB4 TLX3 ZNF267 ZFP14 HIC2 ZKSCAN2 ZNF101 ZNF658B RFX2 ZNF25 RFX3 ZNF354B TLX1 ZNF77 ZNF2 ZNF557 ZNF26 ZNF878 ZFHX4 ZNF530 LBX1 NACC2 ZNF540 ZNF197 ZNF816 ZFHX3 ZNF30	6.96e-09	1412	177	36	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF134 ZBTB38 ZNF143 ZNF672 TBX4 ZNF354A ZNF658 ZNF391 ZFP30 ZBTB4 TLX3 ZNF267 ZFP14 HIC2 ZKSCAN2 ZNF101 ZNF658B RFX2 ZNF25 RFX3 ZNF354B ZNF835 TLX1 ZNF77 ZNF2 ZNF557 ZNF26 ZNF878 ZFHX4 ZNF530 NACC2 ZNF540 ZNF197 ZNF816 ZFHX3 ZNF30	1.63e-08	1459	177	36	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF134 ZBTB38 ZNF143 TBX4 ZNF354A ZNF658 ZFP30 ZBTB4 TLX3 ZNF267 ZFP14 HIC2 ZKSCAN2 ZNF101 ZNF658B RFX2 RFX3 ZNF354B ZNF835 TLX1 ZNF2 ZNF26 ZFHX4 ZNF530 NACC2 ZNF540 ZNF197 ZNF816 ZFHX3 ZNF30	5.09e-07	1244	177	30	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF134 ZBTB38 ZNF143 TBX4 ZNF354A ZNF658 ZFP30 ZBTB4 TLX3 ZNF267 ZFP14 HIC2 ZKSCAN2 ZNF101 ZNF658B RFX2 RFX3 ZNF354B ZNF835 TLX1 ZNF2 ZNF26 ZFHX4 ZNF530 NACC2 ZNF540 ZNF197 ZNF816 ZFHX3 ZNF30	7.97e-07	1271	177	30	GO:0000987
Domain	zf-C2H2	ZNF134 ZBTB38 ZNF143 ZNF672 ZNF234 ZNF354A ZNF658 ZNF391 ZFP30 ZBTB4 ZNF267 ZFP14 HIC2 ZKSCAN2 ZNF101 ZNF25 ZNF354B ZNF835 ZNF77 ZNF2 ZNF557 ZNF26 ZNF878 ZFHX4 ZNF530 ZNF592 ZNF540 ZNF197 ZNF816 ZFHX3 ZNF30	5.93e-13	693	178	31	PF00096
Domain	-	ZNF134 ZBTB38 ZNF143 ZNF672 ZNF234 ZNF354A ZNF658 ZNF391 ZFP30 ZBTB4 ZNF267 ZFP14 HIC2 ZKSCAN2 ZNF101 ZNF25 ZNF354B ZNF835 ZNF77 ZNF2 ZNF557 ZNF26 ZNF878 ZFHX4 ZNF530 ZNF540 ZNF197 ZNF816 ZFHX3 ZNF30	2.01e-12	679	178	30	3.30.160.60
Domain	ZINC_FINGER_C2H2_2	ZNF134 ZBTB38 ZNF143 ZNF672 ZNF234 ZNF354A ZNF658 ZNF391 ZFP30 ZBTB4 ZNF267 ZFP14 HIC2 ZKSCAN2 ZNF101 ZNF25 ZNF354B ZNF835 ZNF77 ZNF2 ZNF557 ZNF26 ZNF878 ZFHX4 ZNF530 ZNF592 ZNF540 ZNF197 ZNF816 ZFHX3 TRMT1L ZNF30	2.04e-12	775	178	32	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF134 ZBTB38 ZNF143 ZNF672 ZNF234 ZNF354A ZNF658 ZNF391 ZFP30 ZBTB4 ZNF267 ZFP14 HIC2 ZKSCAN2 ZNF101 ZNF25 ZNF354B ZNF835 ZNF77 ZNF2 ZNF557 ZNF26 ZNF878 ZFHX4 ZNF530 ZNF592 ZNF540 ZNF197 ZNF816 ZFHX3 TRMT1L ZNF30	2.18e-12	777	178	32	PS00028
Domain	Znf_C2H2/integrase_DNA-bd	ZNF134 ZBTB38 ZNF143 ZNF672 ZNF234 ZNF354A ZNF658 ZNF391 ZFP30 ZBTB4 ZNF267 ZFP14 HIC2 ZKSCAN2 ZNF101 ZNF25 ZNF354B ZNF835 ZNF77 ZNF2 ZNF557 ZNF26 ZNF878 ZFHX4 ZNF530 ZNF540 ZNF197 ZNF816 ZFHX3 ZNF30	3.49e-12	694	178	30	IPR013087
Domain	Znf_C2H2-like	ZNF134 ZBTB38 ZNF143 ZNF672 ZNF234 ZNF354A ZNF658 ZNF391 ZFP30 ZBTB4 ZNF267 ZFP14 HIC2 ZKSCAN2 ZNF101 ZNF25 ZNF354B ZNF835 ZNF77 ZNF2 ZNF557 ZNF26 ZNF878 ZFHX4 ZNF530 ZNF592 ZNF540 ZNF197 ZNF816 ZFHX3 TRMT1L ZNF30	4.14e-12	796	178	32	IPR015880
Domain	Znf_C2H2	ZNF134 ZBTB38 ZNF143 ZNF672 ZNF234 ZNF354A ZNF658 ZNF391 ZFP30 ZBTB4 ZNF267 ZFP14 HIC2 ZKSCAN2 ZNF101 ZNF25 ZNF354B ZNF835 ZNF77 ZNF2 ZNF557 ZNF26 ZNF878 ZFHX4 ZNF530 ZNF592 ZNF540 ZNF197 ZNF816 ZFHX3 TRMT1L ZNF30	5.56e-12	805	178	32	IPR007087
Domain	ZnF_C2H2	ZNF134 ZBTB38 ZNF143 ZNF672 ZNF234 ZNF354A ZNF658 ZNF391 ZFP30 ZBTB4 ZNF267 ZFP14 HIC2 ZKSCAN2 ZNF101 ZNF25 ZNF354B ZNF835 ZNF77 ZNF2 ZNF557 ZNF26 ZNF878 ZFHX4 ZNF530 ZNF592 ZNF540 ZNF197 ZNF816 ZFHX3 TRMT1L ZNF30	6.13e-12	808	178	32	SM00355
Domain	KRAB	ZNF234 ZNF354A ZNF658 ZFP30 ZNF267 ZFP14 ZKSCAN2 ZNF101 ZNF25 ZNF354B ZNF77 ZNF2 ZNF557 ZNF26 ZNF878 ZNF530 ZNF540 ZNF197 ZNF816 ZNF30	2.33e-10	358	178	20	PS50805
Domain	KRAB	ZNF234 ZNF354A ZNF658 ZFP30 ZNF267 ZFP14 ZKSCAN2 ZNF101 ZNF25 ZNF354B ZNF77 ZNF2 ZNF557 ZNF26 ZNF878 ZNF530 ZNF540 ZNF197 ZNF816 ZNF30	2.33e-10	358	178	20	PF01352
Domain	KRAB	ZNF234 ZNF354A ZNF658 ZFP30 ZNF267 ZFP14 ZKSCAN2 ZNF101 ZNF25 ZNF354B ZNF77 ZNF2 ZNF557 ZNF26 ZNF878 ZNF530 ZNF540 ZNF197 ZNF816 ZNF30	3.96e-10	369	178	20	SM00349
Domain	KRAB	ZNF234 ZNF354A ZNF658 ZFP30 ZNF267 ZFP14 ZKSCAN2 ZNF101 ZNF25 ZNF354B ZNF77 ZNF2 ZNF557 ZNF26 ZNF878 ZNF530 ZNF540 ZNF197 ZNF816 ZNF30	4.15e-10	370	178	20	IPR001909
Domain	zf-C2H2_6	ZNF672 ZNF234 ZNF354A ZNF658 ZNF391 ZFP30 ZNF267 ZFP14 ZNF25 ZNF354B ZNF77 ZNF26 ZNF878 ZNF530 ZNF540 ZNF197 ZNF816 ZNF30	1.29e-09	314	178	18	PF13912
Domain	Autophagy-rel_C	VPS13C ATG2A VPS13B	8.39e-06	5	178	3	IPR015412
Domain	ATG_C	VPS13C ATG2A VPS13B	8.39e-06	5	178	3	PF09333
Domain	BTB	ZBTB38 BTBD8 ZBTB4 ENC1 HIC2 KLHL38 NACC2 ABTB2	3.71e-05	131	178	8	PF00651
Domain	Chorein_N	VPS13C ATG2A VPS13B	4.60e-05	8	178	3	PF12624
Domain	VPS13_N	VPS13C ATG2A VPS13B	4.60e-05	8	178	3	IPR026854
Domain	BTB	ZBTB38 BTBD8 ZBTB4 ENC1 HIC2 KLHL38 NACC2 KCNF1 ABTB2	5.86e-05	180	178	9	SM00225
Domain	zf-C2H2_11	ZNF354A ZNF354B ZNF592	6.85e-05	9	178	3	PF16622
Domain	BTB/POZ_dom	ZBTB38 BTBD8 ZBTB4 ENC1 HIC2 KLHL38 NACC2 KCNF1 ABTB2	7.24e-05	185	178	9	IPR000210
Domain	SKP1/BTB/POZ	ZBTB38 BTBD8 ZBTB4 ENC1 HIC2 KLHL38 NACC2 KCNF1 ABTB2	8.53e-05	189	178	9	IPR011333
Domain	BTB	ZBTB38 BTBD8 ZBTB4 ENC1 HIC2 KLHL38 NACC2 ABTB2	1.52e-04	160	178	8	PS50097
Domain	RFX1_trans_act	RFX2 RFX3	2.69e-04	3	178	2	IPR007668
Domain	RFX1_trans_act	RFX2 RFX3	2.69e-04	3	178	2	PF04589
Domain	ARM-type_fold	RIPOR2 INTS1 BTAF1 MAP3K1 PIK3R4 IFRD1 PIK3C2B WDFY3 HEATR5B GCN1 STAG3	4.21e-04	339	178	11	IPR016024
Domain	SHR-BD	VPS13C VPS13B	5.35e-04	4	178	2	IPR009543
Domain	VPS13_C	VPS13C VPS13B	5.35e-04	4	178	2	PF16909
Domain	VPS13_C	VPS13C VPS13B	5.35e-04	4	178	2	IPR031645
Domain	SHR-BD	VPS13C VPS13B	5.35e-04	4	178	2	PF06650
Domain	Ion_trans_dom	CACNA1C TRPC4 TRPC5 RYR2 KCNF1 TRPM8	7.85e-04	114	178	6	IPR005821
Domain	Ion_trans	CACNA1C TRPC4 TRPC5 RYR2 KCNF1 TRPM8	7.85e-04	114	178	6	PF00520
Domain	HISTONE_H2B	H2BC13 H2BC20P H2BC19P	9.98e-04	21	178	3	PS00357
Domain	Histone_H2B	H2BC13 H2BC20P H2BC19P	9.98e-04	21	178	3	IPR000558
Domain	H2B	H2BC13 H2BC20P H2BC19P	9.98e-04	21	178	3	SM00427
Domain	Spectrin	SPTBN4 DST SYNE2	1.31e-03	23	178	3	PF00435
Domain	ACTININ_2	SPTBN4 DST SYNE2	1.31e-03	23	178	3	PS00020
Domain	ACTININ_1	SPTBN4 DST SYNE2	1.31e-03	23	178	3	PS00019
Domain	Actinin_actin-bd_CS	SPTBN4 DST SYNE2	1.31e-03	23	178	3	IPR001589
Domain	TRP_2	TRPC4 TRPC5	1.32e-03	6	178	2	PF08344
Domain	TRP_dom	TRPC4 TRPC5	1.32e-03	6	178	2	IPR013555
Domain	-	RIPOR2 BTAF1 PIK3R4 IFRD1 WDFY3 HEATR5B GCN1 STAG3	1.33e-03	222	178	8	1.25.10.10
Domain	TRPC_channel	TRPC4 TRPC5	1.84e-03	7	178	2	IPR002153
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DPH2 SLC37A3 ZBTB4 INTS1 POMGNT1 BTAF1 INO80 ATG2A ARHGAP35 NSD3 SLC38A10 DST SBF1 PIK3C2B ZNF592 SLC35A2 STRN4 PDCD11 WDFY3 GCN1 ABTB2 PICK1	9.99e-08	1105	183	22	35748872
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF354A ZNF267 ZNF101 ZNF25 ZNF354B ZNF77 ZNF878 ZNF197 GCN1	5.48e-07	181	183	9	37372979
Pubmed	Genetic and age related models of neurodegeneration in mice: dystrophic axons.	ATP8A2 SPTBN4 DST	5.71e-07	4	183	3	1634998
Pubmed	A census of human transcription factors: function, expression and evolution.	ZBTB38 ZNF143 TBX4 ZBTB4 TLX3 ZNF267 HIC2 ZKSCAN2 RFX2 ZNF25 RFX3 TLX1 ZNF26 ZFHX4 LBX1 ZNF197 ZFHX3 ZNF30	1.66e-06	908	183	18	19274049
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CUL3 ZNF143 THNSL1 EI24 BTAF1 PTK2 PIK3R4 TAOK3 DST SBF1 ARHGEF7 MARF1 CARD6 ILVBL SORL1	2.06e-06	650	183	15	38777146
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	CUL3 ZNF234 F5 LRRC52 SPTBN4 ZFHX4 ZNF592 EFCAB12 RPUSD3 ADAMTS18 MTBP	3.76e-06	361	183	11	26167880
Pubmed	mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.	BTBD8 INTS1 BMP1 DST SYNE2 UCN3	1.38e-05	98	183	6	34943047
Pubmed	Expression of zfh-4, a new member of the zinc finger-homeodomain family, in developing brain and muscle.	ZNF101 ZFHX4	2.75e-05	2	183	2	7537552
Pubmed	The mouse ZFH-4 protein contains four homeodomains and twenty-two zinc fingers.	ZFHX4 ZFHX3	2.75e-05	2	183	2	10873665
Pubmed	Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.	TRPC4 TRPC5	2.75e-05	2	183	2	22457348
Pubmed	FAK potentiates Rac1 activation and localization to matrix adhesion sites: a role for betaPIX.	PTK2 ARHGEF7	2.75e-05	2	183	2	17093062
Pubmed	Conserved gating elements in TRPC4 and TRPC5 channels.	TRPC4 TRPC5	2.75e-05	2	183	2	23677990
Pubmed	Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells.	TRPC4 TRPC5	2.75e-05	2	183	2	32033274
Pubmed	CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release.	PTK2 CNR1	2.75e-05	2	183	2	24089517
Pubmed	The first ankyrin-like repeat is the minimum indispensable key structure for functional assembly of homo- and heteromeric TRPC4/TRPC5 channels.	TRPC4 TRPC5	2.75e-05	2	183	2	17624425
Pubmed	Thymic adult T-cell acute lymphoblastic leukemia stratified in standard- and high-risk group by aberrant HOX11L2 expression: experience of the German multicenter ALL study group.	TLX3 TLX1	2.75e-05	2	183	2	18368072
Pubmed	Downregulation of TRPC4 and TRPC5 Inhibits Smooth Muscle Cell Proliferation without Affecting Endothelial Cell Proliferation.	TRPC4 TRPC5	2.75e-05	2	183	2	34899056
Pubmed	Corticolimbic expression of TRPC4 and TRPC5 channels in the rodent brain.	TRPC4 TRPC5	2.75e-05	2	183	2	17593972
Pubmed	Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice.	TRPC4 TRPC5	2.75e-05	2	183	2	26317356
Pubmed	A novel capacitative calcium entry channel expressed in excitable cells.	TRPC4 TRPC5	2.75e-05	2	183	2	9687496
Pubmed	Skeletal and cardiac ryanodine receptors bind to the Ca(2+)-sensor region of dihydropyridine receptor alpha(1C) subunit.	CACNA1C RYR2	2.75e-05	2	183	2	11576544
Pubmed	Characterization of the mouse Kid1 gene and identification of a highly related gene, Kid2.	ZNF354A ZNF354B	2.75e-05	2	183	2	10564808
Pubmed	TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A.	TRPC4 TRPC5	2.75e-05	2	183	2	30038709
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	CACNA1C TRPC4 TRPC5 RYR2	4.76e-05	38	183	4	30786075
Pubmed	Pigmentation-related genes and their implication in malignant melanoma susceptibility.	ATRN HPS1 VPS13B	5.00e-05	14	183	3	19320733
Pubmed	Ptf1a, Lbx1 and Pax2 coordinate glycinergic and peptidergic transmitter phenotypes in dorsal spinal inhibitory neurons.	TLX3 TLX1 LBX1	6.22e-05	15	183	3	18634777
Pubmed	Tlx1 and Tlx3 coordinate specification of dorsal horn pain-modulatory peptidergic neurons.	TLX3 TLX1 LBX1	6.22e-05	15	183	3	18400903
Pubmed	Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.	TLX3 GRM8 TLX1 LBX1 GRIN3A	7.08e-05	81	183	5	22723691
Pubmed	MEK kinase 1 interacts with focal adhesion kinase and regulates insulin receptor substrate-1 expression.	PTK2 MAP3K1	8.23e-05	3	183	2	12458213
Pubmed	Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory.	TRPC4 TRPC5	8.23e-05	3	183	2	28790178
Pubmed	Characterization of the human and mouse unconventional myosin XV genes responsible for hereditary deafness DFNB3 and shaker 2.	DRG2 MYO15A	8.23e-05	3	183	2	10552926
Pubmed	Involvement of RFX proteins in transcriptional activation from a Ras-responsive enhancer element.	RFX2 RFX3	8.23e-05	3	183	2	15024578
Pubmed	Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL.	TLX3 TLX1	8.23e-05	3	183	2	22366949
Pubmed	Differential PI(4,5)P2 sensitivities of TRPC4, C5 homomeric and TRPC1/4, C1/5 heteromeric channels.	TRPC4 TRPC5	8.23e-05	3	183	2	30755645
Pubmed	Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains.	RFX2 RFX3	8.23e-05	3	183	2	10330134
Pubmed	Ciliogenic RFX transcription factors regulate FGF1 gene promoter.	RFX2 RFX3	8.23e-05	3	183	2	22415835
Pubmed	Clinical significance of HOX11L2 expression linked to t(5;14)(q35;q32), of HOX11 expression, and of SIL-TAL fusion in childhood T-cell malignancies: results of EORTC studies 58881 and 58951.	TLX3 TLX1	8.23e-05	3	183	2	14504110
Pubmed	An NGS-based genotyping in LQTS; minor genes are no longer minor.	CACNA1C RYR2	8.23e-05	3	183	2	32681117
Pubmed	Histologic features of melanoma associated with germline mutations of CDKN2A, CDK4, and POT1 in melanoma-prone families from the United States, Italy, and Spain.	POT1 CDK4	8.23e-05	3	183	2	32283231
Pubmed	The PDZ domain protein PICK1 and the sodium channel BNaC1 interact and localize at mechanosensory terminals of dorsal root ganglion neurons and dendrites of central neurons.	ASIC1 PICK1	8.23e-05	3	183	2	11739374
Pubmed	MEN1 tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2.	MEN1 CDK4	8.23e-05	3	183	2	24531709
Pubmed	Drosophila regulatory factor X is necessary for ciliated sensory neuron differentiation.	RFX2 RFX3	8.23e-05	3	183	2	12403718
Pubmed	Suppression of RhoA activity by focal adhesion kinase-induced activation of p190RhoGAP: role in regulation of endothelial permeability.	ARHGAP35 PTK2	8.23e-05	3	183	2	16308318
Pubmed	TLX homeodomain oncogenes mediate T cell maturation arrest in T-ALL via interaction with ETS1 and suppression of TCRα gene expression.	TLX3 TLX1	8.23e-05	3	183	2	22516263
Pubmed	Androglobin gene expression patterns and FOXJ1-dependent regulation indicate its functional association with ciliogenesis.	RFX2 ADGB	8.23e-05	3	183	2	33453283
Pubmed	Interplay of RFX transcription factors 1, 2 and 3 in motile ciliogenesis.	RFX2 RFX3	8.23e-05	3	183	2	32725242
Pubmed	Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST.	POT1 DCLRE1B	8.23e-05	3	183	2	22748632
Pubmed	Transient Receptor Potential C 1/4/5 Is a Determinant of MTI-101 Induced Calcium Influx and Cell Death in Multiple Myeloma.	TRPC4 TRPC5	8.23e-05	3	183	2	34199280
Pubmed	Joint CB1 and NGF Receptor Activation Suppresses TRPM8 Activation in Etoposide-Resistant Retinoblastoma Cells.	TRPM8 CNR1	8.23e-05	3	183	2	38339011
Pubmed	A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.	TLX3 TLX1	8.23e-05	3	183	2	11587205
Pubmed	FAK is required for TGFbeta-induced JNK phosphorylation in fibroblasts: implications for acquisition of a matrix-remodeling phenotype.	PTK2 MAP3K1	8.23e-05	3	183	2	17409352
Pubmed	TRPC1/4/5 channels contribute to morphine-induced analgesic tolerance and hyperalgesia by enhancing spinal synaptic potentiation and structural plasticity.	TRPC4 TRPC5	8.23e-05	3	183	2	32359120
Pubmed	A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins.	ZNF354A ZNF2	8.23e-05	3	183	2	8986806
Pubmed	CXXC5 drove inflammation and ovarian cancer proliferation via transcriptional activation of ZNF143 and EGR1.	ZNF143 CXXC5	8.23e-05	3	183	2	38642782
Pubmed	Differentially regulated ADAMTS1, 8, and 18 in gastric adenocarcinoma.	ADAMTS1 ADAMTS18	8.23e-05	3	183	2	28814085
Pubmed	ASIC1-mediated calcium entry stimulates NFATc3 nuclear translocation via PICK1 coupling in pulmonary arterial smooth muscle cells.	ASIC1 PICK1	8.23e-05	3	183	2	27190058
Pubmed	RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins.	RFX2 RFX3	8.23e-05	3	183	2	8289803
Pubmed	Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.	TRPC4 TRPC5	8.23e-05	3	183	2	28325835
Pubmed	Mot1, Ino80C, and NC2 Function Coordinately to Regulate Pervasive Transcription in Yeast and Mammals.	BTAF1 INO80	8.23e-05	3	183	2	28735899
Pubmed	Development expression of Hox11 and specification of splenic cell fate.	TLX3 TLX1	8.23e-05	3	183	2	7747804
Pubmed	GluN3A expression restricts spine maturation via inhibition of GIT1/Rac1 signaling.	ARHGEF7 GRIN3A	8.23e-05	3	183	2	24297929
Pubmed	Dual action of the Gαq-PLCβ-PI(4,5)P2 pathway on TRPC1/4 and TRPC1/5 heterotetramers.	TRPC4 TRPC5	8.23e-05	3	183	2	30108272
Pubmed	Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.	ASIC1 TRPC4 TRPC5 TRPM8	8.54e-05	44	183	4	19322198
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	TRPC5 POT1 F5 RYR2 DST SYNE2 MARF1	8.82e-05	197	183	7	20811636
Pubmed	Inhibition of core histones acetylation by carcinogenic nickel(II).	H2BC13 H2BC20P H2BC19P	1.10e-04	18	183	3	16283522
Pubmed	Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase.	H2BC13 H2BC20P H2BC19P	1.10e-04	18	183	3	12757711
Pubmed	Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.	ZFP30 GAS7 USP37 SPTBN4 SBF1 NUP210	1.11e-04	142	183	6	19851296
Pubmed	A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.	BTBD8 ZNF101 H2BC13 EFHC1 LIPE LOXHD1 GRIN3A	1.13e-04	205	183	7	12040188
Pubmed	Association of genetic variants with hemorrhagic stroke in Japanese individuals.	ZFP30 GAS7 USP37 SPTBN4 SBF1 NUP210	1.15e-04	143	183	6	20198315
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	ATRN MYH3 BAZ2B VPS13C INTS1 HIC2 IGSF10 SLC38A10 LOXHD1 DST ZNF592 BTD ATIC	1.54e-04	736	183	13	29676528
Pubmed	N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.	DPH2 VPS13C RFX2 ZNF77 SLC38A10 CEP89 ZNF592	1.60e-04	217	183	7	34048709
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ATRN ZBTB38 ZNF234 ADAMTS1 ZBTB4 ENC1 CXXC5 GAS7 PTK2 PIK3R4 SPTBN4 UBA7 DST ZNF592 ZNF197 ATIC WDFY3 PICK1	1.62e-04	1285	183	18	35914814
Pubmed	Interaction of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel).	ASIC1 PICK1	1.64e-04	4	183	2	11802773
Pubmed	Interaction with dopamine D2 receptor enhances expression of transient receptor potential channel 1 at the cell surface.	TRPC4 TRPC5	1.64e-04	4	183	2	18261457
Pubmed	Human regulatory factor X 4 (RFX4) is a testis-specific dimeric DNA-binding protein that cooperates with other human RFX members.	RFX2 RFX3	1.64e-04	4	183	2	11682486
Pubmed	The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5.	TRPC4 TRPC5	1.64e-04	4	183	2	20164195
Pubmed	Characterization of P4 ATPase Phospholipid Translocases (Flippases) in Human and Rat Pancreatic Beta Cells: THEIR GENE SILENCING INHIBITS INSULIN SECRETION.	ATP8A2 ATP9A	1.64e-04	4	183	2	26240149
Pubmed	Differential expression of Rfx1-4 during mouse spermatogenesis.	RFX2 RFX3	1.64e-04	4	183	2	19596083
Pubmed	Identification of a novel population in high-grade oligodendroglial tumors not deleted on 1p/19q using array CGH.	PIK3C2B CDK4	1.64e-04	4	183	2	22825724
Pubmed	Transcriptional regulation of the Alström syndrome gene ALMS1 by members of the RFX family and Sp1.	RFX2 ALMS1	1.64e-04	4	183	2	20381594
Pubmed	Systematic and quantitative mRNA expression analysis of TRP channel genes at the single trigeminal and dorsal root ganglion level in mouse.	TRPC4 TRPM8	1.64e-04	4	183	2	23410158
Pubmed	BPOZ-2 is a negative regulator of the NLPR3 inflammasome contributing to SARS-CoV-2-induced hyperinflammation.	CUL3 ABTB2	1.64e-04	4	183	2	36936774
Pubmed	Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias.	CACNA1C RYR2	1.64e-04	4	183	2	19383796
Pubmed	Transcriptional activation by TLX1/HOX11 involves Gro/TLE corepressors.	TLX3 TLX1	1.64e-04	4	183	2	19250647
Pubmed	Signalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases.	PTK2 CDK4	1.64e-04	4	183	2	31296956
Pubmed	Odontoblast TRPC5 channels signal cold pain in teeth.	TRPC5 TRPM8	1.64e-04	4	183	2	33771873
Pubmed	Analysis of the human VPS13 gene family.	VPS13C VPS13B	1.64e-04	4	183	2	15498460
Pubmed	The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes.	TLX3 TLX1	1.64e-04	4	183	2	8099440
Pubmed	A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells.	ARHGAP35 PTK2	1.64e-04	4	183	2	19435801
Pubmed	NMDA receptor-dependent synaptic activation of TRPC channels in olfactory bulb granule cells.	TRPC4 TRPC5	1.64e-04	4	183	2	22539836
Pubmed	Behavioral abnormalities observed in Zfhx2-deficient mice.	ZFHX4 ZFHX3	1.64e-04	4	183	2	23300874
Pubmed	A family of human zinc finger proteins that bind methylated DNA and repress transcription.	ZBTB38 ZBTB4	1.64e-04	4	183	2	16354688
Pubmed	cAMP-dependent protein kinase phosphorylation of the acid-sensing ion channel-1 regulates its binding to the protein interacting with C-kinase-1.	ASIC1 PICK1	1.64e-04	4	183	2	12578970
Pubmed	Transient Receptor Potential Canonical 5-Scramblase Signaling Complex Mediates Neuronal Phosphatidylserine Externalization and Apoptosis.	TRPC4 TRPC5	1.64e-04	4	183	2	32110987
Pubmed	Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms.	TRPC4 TRPC5	1.64e-04	4	183	2	23188715
Pubmed	Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.	ATRN ATP8A2 ATP9A ALG9 TRPM8	1.92e-04	100	183	5	26073538
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	CDK20 TTF2 ZNF143 HIC2 BTAF1 RFX2 RFX3 MEN1 IFRD1 UBA7 ZFHX4 NACC2 TRMT1L SORL1	1.92e-04	857	183	14	25609649
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	HIC2 ARHGAP35 DST ALMS1 SYNE2 WDFY3 GCN1	2.00e-04	225	183	7	12168954
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ZFP14 ZDBF2 KIAA1586 USP37 SPTBN4	2.01e-04	101	183	5	10997877
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DRG2 SPATA18 NAA10 NSD3 PIK3R4 IFRD1 H2BC13 DST ALMS1 SBF1 PIK3C2B CEP89 SYNE2 ABTB2	2.02e-04	861	183	14	36931259
Cytoband	6q14-q15	HTR1E CNR1	3.28e-04	7	183	2	6q14-q15
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF134 ZNF234 ZFP30 ZFP14 ARHGAP35 ZNF835 SPTBN4 LIPE ZNF530 CEP89 ZNF540 STRN4 ZNF816 ZNF30	3.30e-04	1192	183	14	chr19q13
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF134 ZBTB38 ZNF143 ZNF672 ZNF234 ZNF354A ZNF658 ZNF391 ZFP30 ZBTB4 ZNF267 ZFP14 HIC2 ZKSCAN2 ZNF101 ZNF25 ZNF354B ZNF835 ZNF77 ZNF2 ZNF557 ZNF26 ZNF878 ZNF530 ZNF592 ZNF540 ZNF197 ZNF816 ZFHX3 ZNF30	3.21e-14	718	141	30	28
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	ZBTB38 BTBD8 ZBTB4 ENC1 HIC2 KLHL38 NACC2 ABTB2	1.02e-05	134	141	8	861
GeneFamily	Transient receptor potential cation channels	TRPC4 TRPC5 TRPM8	1.32e-03	28	141	3	249
GeneFamily	Regulatory factor X family	RFX2 RFX3	1.64e-03	8	141	2	1153
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	CUL3 ATRN VPS13C ZFP30 ZDBF2 BTAF1 PTPRU TAOK3 DST ALMS1 NACC2 PIK3C2B BTD SYNE2 NUP210 ERMARD ABTB2	2.44e-05	654	172	17	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	CUL3 TTF2 VPS13C POT1 CXXC5 ZDBF2 BTAF1 USP37 RFX3 PTK2 IFRD1 ALMS1 MTBP TRMT1L WDR44	2.98e-05	532	172	15	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	INTS1 BMP1 MAPK15 NACC2 ADAMTS18 TRPM8 ACKR2 ABTB2	1.57e-06	196	183	8	7be50b9156394dea44d7b8b476d4dd516abfafae
ToppCell	TCGA-Skin-Metastatic-Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	EXOC6 ZBTB38 ZNF143 VPS13C USP37 ALMS1 ZFHX3 TRMT1L	1.69e-06	198	183	8	af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCell	TCGA-Skin-Metastatic\|TCGA-Skin / Sample_Type by Project: Shred V9	EXOC6 ZBTB38 ZNF143 VPS13C USP37 ALMS1 ZFHX3 TRMT1L	1.69e-06	198	183	8	ad39cce004867f083f8da1954e0cf5a263815184
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	EXOC6 ZBTB38 ZNF143 VPS13C USP37 ALMS1 ZFHX3 TRMT1L	1.69e-06	198	183	8	62cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPATA18 ADGB WDR93 EFHC1 MAPK15 EFCAB12 LRRC53	9.80e-06	180	183	7	92fb01b91261b3103454924cde56add337b41844
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	ENC1 USP37 MAP3K1 ALMS1 MARF1 TRMT1L VPS13B	1.21e-05	186	183	7	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	tumor_Lung-Epithelial_cells-tS3\|Epithelial_cells / Location, Cell class and cell subclass	RIPOR2 SPATA18 DRC1 ADGB EFHC1 MAPK15 EFCAB12	1.26e-05	187	183	7	3cea677279e71fdb9879530dea10a5e6393beacd
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	DPP6 RYR2 IGSF10 EFHC1 ZFHX4 ZFHX3 GRIN3A	1.39e-05	190	183	7	6e92c78799f34b31d098854503c796edb0dc7f80
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SPATA18 DRC1 RFX2 RFX3 ADGB EFHC1 MAPK15	1.65e-05	195	183	7	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SPATA18 DRC1 RFX2 RFX3 ADGB EFHC1 MAPK15	1.65e-05	195	183	7	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	NS-control-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SPATA18 DRC1 RFX3 ADGB EFHC1 MAPK15 EFCAB12	1.70e-05	196	183	7	d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SPATA18 DRC1 RFX2 RFX3 ADGB EFHC1 MAPK15	1.76e-05	197	183	7	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	severe-Myeloid-Neutrophils_4\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RIPOR2 TDRD9 ATP9A F5 SYNE2 WDFY3 SORL1	1.88e-05	199	183	7	50242666def13e5d4149c563ae000d6768f086f7
ToppCell	severe-Myeloid-Neutrophils_4\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RIPOR2 TDRD9 NCF2 ATP9A F5 WDFY3 SORL1	1.94e-05	200	183	7	b665f36dcf3c9d3981ee96f2973512f751612542
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C TBX4 ADAMTS1 TRPC4 GAS7 RYR2 DST	1.94e-05	200	183	7	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Cilia-bearing_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	SPATA18 DRC1 GRM8 F5 ADGB MAPK15 EFCAB12	1.94e-05	200	183	7	177f9ad8dd8635394c575a2b30140184df0bd51e
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RFX3 ADGB EFHC1 MAPK15 EFCAB12 WDR86	7.13e-05	169	183	6	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-7\|TCGA-Breast / Sample_Type by Project: Shred V9	DPH2 SRSF12 NOP58 IFRD1 RPUSD3 ERI3	7.86e-05	172	183	6	a2c3b790be85f7fd23f2dc919dcc749656920e71
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPATA18 DRC1 RFX3 KLHL38 EFHC1 MAPK15	8.11e-05	173	183	6	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	PCW_13-14-Epithelial-Epithelial_ciliated\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DPP6 SPATA18 DRC1 ADGB WDR93 MAPK15	8.64e-05	175	183	6	b1369d2b74f461e6822d0c33e9b50fe0dfbceb54
ToppCell	PCW_13-14-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DPP6 SPATA18 DRC1 ADGB WDR93 MAPK15	8.64e-05	175	183	6	c82ec6deb6ccdd991a69a62b6d62d5b14c803d7a
ToppCell	NS-critical-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CDK20 CACNA1C RFX3 MAPK15 EFCAB12 WDR86	8.92e-05	176	183	6	b794275fdd757b8fa2108e3c867f23da2649146d
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	HMGCR SRSF12 BMP1 DST ARHGEF7 PDCD11	9.20e-05	177	183	6	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	COVID-19-Heart-VSMC\|Heart / Disease (COVID-19 only), tissue and cell type	CACNA1C ADAMTS1 TRPC4 BMP1 ARHGEF7 ZFHX3	9.78e-05	179	183	6	a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPATA18 DRC1 ADGB WDR93 EFHC1 VWA5B1	1.07e-04	182	183	6	587636c0f127231de21acd8aa632b74ff22ca8c2
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPATA18 DRC1 ADGB WDR93 EFHC1 VWA5B1	1.07e-04	182	183	6	adfadd7893e74b3002f13f00875e3667d3493e0c
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RIPOR2 TDRD9 NCF2 ATG2A F5 SORL1	1.14e-04	184	183	6	7ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SPATA18 DRC1 ADGB WDR93 MAPK15 EFCAB12	1.17e-04	185	183	6	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	SPATA18 RFX3 ADGB WDR93 EFHC1 MAPK15	1.17e-04	185	183	6	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SPATA18 DRC1 ADGB WDR93 MAPK15 EFCAB12	1.17e-04	185	183	6	3e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CXXC5 SHC4 GAS7 PMEPA1 LRRC52 DST	1.17e-04	185	183	6	dd17025d8c423aa0a451ac7f1f301c93528e0229
ToppCell	Mild-NK\|World / Disease group and Cell class	ADAMTS1 BAZ2B CXXC5 GAS7 PTK2 ACKR2	1.17e-04	185	183	6	0565b7c464e1a09e596f5a0b363d2dc9b55c3c50
ToppCell	COPD-Stromal-Pericyte\|World / Disease state, Lineage and Cell class	CACNA1C TBX4 ADAMTS1 TRPC4 RYR2 LRRC53	1.21e-04	186	183	6	8adfd2d1fda4e8aecc95192ea627bf7ed5214b8d
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	ZNF672 GAS7 F5 TIMM21 JRK ERMARD	1.24e-04	187	183	6	3c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SPATA18 DRC1 ADGB WDR93 MAPK15 EFCAB12	1.24e-04	187	183	6	9e10ed56090d82589bc457788282f664b70ace4b
ToppCell	tumor_Lung-Epithelial_cells-tS3\|tumor_Lung / Location, Cell class and cell subclass	SPATA18 DRC1 ADGB EFHC1 MAPK15 EFCAB12	1.28e-04	188	183	6	26326b4e298e33f9ba393fc632238aa8c54b1ea3
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	SPATA18 DRC1 ADGB WDR93 MAPK15 EFCAB12	1.28e-04	188	183	6	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SPATA18 DRC1 ADGB WDR93 MAPK15 EFCAB12	1.28e-04	188	183	6	2b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCell	COVID-19-lung-Ciliated\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SPATA18 DRC1 ADGB WDR93 MAPK15 EFCAB12	1.32e-04	189	183	6	a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCell	cellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ATRN POT1 ZNF267 KIAA1586 ZNF557 PIK3C2B	1.32e-04	189	183	6	bccb3481ffed597c845fe860da658505316105b5
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SPATA18 DRC1 ADGB WDR93 MAPK15 EFCAB12	1.32e-04	189	183	6	68a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	SPATA18 DRC1 ADGB WDR93 MAPK15 EFCAB12	1.32e-04	189	183	6	dc440015949a768188c67661b6be63b1ead1a0f0
ToppCell	droplet-Lung-18m-Epithelial-airway_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPATA18 DRC1 ADGB WDR93 EFHC1 MAPK15	1.32e-04	189	183	6	fe958fdf9963c2dfe270f67f0da36b3264d0017c
ToppCell	Adult-Epithelial-ciliated_cell\|Adult / Lineage, Cell type, age group and donor	SPATA18 DRC1 ADGB WDR93 MAPK15 EFCAB12	1.32e-04	189	183	6	b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	SPATA18 DRC1 ADGB WDR93 MAPK15 EFCAB12	1.32e-04	189	183	6	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	SPATA18 DRC1 RFX2 RFX3 ADGB EFHC1	1.36e-04	190	183	6	9ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell	facs-Lung-nan-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPATA18 DRC1 KLHL38 ADGB WDR93 MAPK15	1.36e-04	190	183	6	e243b5fbb17b9ec3cc90bbe970c1d30b0fd1c2e1
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	SPATA18 DRC1 RFX2 RFX3 ADGB EFHC1	1.36e-04	190	183	6	833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell	facs-Lung-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPATA18 DRC1 KLHL38 ADGB WDR93 MAPK15	1.36e-04	190	183	6	fe844559b95832845d2e8d3ab4b57e3d558bc372
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RIPOR2 ZNF354A ATG2A ZNF540 SYNE2 PDCD11	1.36e-04	190	183	6	69c5c4d5f4fb6e5ae2c9dbf9d209faf093c3f769
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPATA18 DRC1 RFX3 ADGB EFHC1 MAPK15	1.48e-04	193	183	6	e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPP6 SPATA18 F5 PMEPA1 DST SRGAP2B	1.48e-04	193	183	6	3eaa0461618582a1754400624350d269d24e750a
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DPP6 CXXC5 SHC4 GAS7 PMEPA1 DST	1.48e-04	193	183	6	66af80f4b51e1ce97b6fb7c630dc5f95bfa7e7d4
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SPATA18 ADGB IGSF10 EFHC1 MAPK15 EFCAB12	1.48e-04	193	183	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	15-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	SPATA18 DRC1 RFX2 RFX3 EFHC1 MAPK15	1.48e-04	193	183	6	aa3acc7571405169efb656d214f3a8cbf988362e
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like-IPCs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	ASIC1 BAZ2B ENC1 CXXC5 SYNE2 CNR1	1.48e-04	193	183	6	2088f1d210c73f74685492c63065c62ac3f553e9
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	ASIC1 BAZ2B ENC1 CXXC5 SYNE2 CNR1	1.48e-04	193	183	6	f24bae40f5cbcfece04fbefe4e3de1b88ac90de4
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature-Adult_Glia\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHC4 GAS7 PMEPA1 DST ZFHX4 WDR86	1.52e-04	194	183	6	d429bb5e422a07bd92f0dc48cd51528e8b7d9a72
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	THNSL1 BTBD8 ATP8A2 ZKSCAN2 WDR86 CDK4	1.52e-04	194	183	6	5031f324628ff12a33e84cc52157be4786e0961d
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHC4 GAS7 PMEPA1 DST ZFHX4 WDR86	1.52e-04	194	183	6	bffdf6db0bf3fb338e7bb0789ae7dcde1fce0094
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHC4 GAS7 PMEPA1 DST ZFHX4 WDR86	1.52e-04	194	183	6	408dfc7060095972a54ae37ae8105521df6fbbee
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPATA18 DRC1 RFX3 ADGB EFHC1 MAPK15	1.56e-04	195	183	6	0e763f36786515698b593e5c93f6a56619c1242d
ToppCell	COVID-19-Lymphoid-Tregs\|Lymphoid / Condition, Lineage and Cell class	ZBTB38 ZNF101 F5 NSD3 SYNE2 CARD6	1.56e-04	195	183	6	9ad844d9d5aac39d133ae8ab9c4839300f08064c
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPATA18 DRC1 RFX3 ADGB EFHC1 MAPK15	1.56e-04	195	183	6	581b04220587e1d5198b1abd6965965ace7803e7
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPATA18 DRC1 RFX3 ADGB EFHC1 MAPK15	1.56e-04	195	183	6	93b1559382a12cfb158aa5fac7386e38b4f87989
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	CACNA1C TBX4 ADAMTS1 TRPC4 RYR2 DST	1.56e-04	195	183	6	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPATA18 DRC1 RFX3 ADGB EFHC1 MAPK15	1.56e-04	195	183	6	79dc031258579ea328181dda33710dd897f1064a
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB38 VPS13C USP37 IGSF10 NOP58 ZFHX4	1.56e-04	195	183	6	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	ILEUM-non-inflamed-(9)_Enteric_neurons\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SHC4 GAS7 PMEPA1 DST ZFHX4 WDR86	1.60e-04	196	183	6	998aa523555ed6bc9c1b5cacbf7ba77c7b218e6b
ToppCell	10x5'-Liver-Lymphocytic_NK-NK_CD16\|Liver / Manually curated celltypes from each tissue	ADAMTS1 ENC1 CXXC5 GK5 SYNE2 SORL1	1.60e-04	196	183	6	e6d4853ccefbcd45a019cee595811f0474dcc036
ToppCell	ILEUM-non-inflamed-(9)_Neuro_cell\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SHC4 GAS7 PMEPA1 DST ZFHX4 WDR86	1.60e-04	196	183	6	2b08cd6730119d5dea0152709ab8de580b66cd3c
ToppCell	COVID-19-lung-Pericytes/_Smooth_Muscle\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1C TBX4 ADAMTS1 TRPC4 RYR2 ZFHX3	1.60e-04	196	183	6	754a3613340932563cd8424d775e18b93c3a1aaa
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ADAMTS1 GRM8 RYR2 IGSF10 DST WDR86	1.65e-04	197	183	6	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPATA18 DRC1 RFX3 ADGB EFHC1 MAPK15	1.65e-04	197	183	6	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG\|World / Primary Cells by Cluster	CXXC5 DRC1 PMEPA1 ZFHX4 NACC2 NUP210	1.65e-04	197	183	6	61749ccafeb938c310cff1de5ff924a1c794325a
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPATA18 DRC1 RFX3 ADGB EFHC1 MAPK15	1.65e-04	197	183	6	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RFX3 ADGB WDR93 MAPK15 EFCAB12 SYNE2	1.65e-04	197	183	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPATA18 DRC1 RFX3 ADGB EFHC1 MAPK15	1.65e-04	197	183	6	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	control-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SPATA18 DRC1 RFX3 ADGB EFHC1 MAPK15	1.65e-04	197	183	6	e453d085182364ca347cbcc9dc995c62c3353016
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPATA18 DRC1 RFX3 ADGB EFHC1 MAPK15	1.65e-04	197	183	6	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	Parenchymal-NucSeq-Stromal-Pericyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C TBX4 ADAMTS1 TRPC4 ZNF835 RYR2	1.65e-04	197	183	6	41dd312f46a2b983c8d864adeb6970c0ca4a8048
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG-25\|World / Primary Cells by Cluster	CXXC5 DRC1 PMEPA1 ZFHX4 NACC2 NUP210	1.65e-04	197	183	6	9d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCell	control-Epithelial-Ciliated\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SPATA18 DRC1 RFX3 ADGB EFHC1 MAPK15	1.65e-04	197	183	6	d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-Treg\|ICU-SEP / Disease, condition lineage and cell class	ATP8A2 ZDBF2 ZNF101 H2BC13 SYNE2 ATIC	1.65e-04	197	183	6	c3ee2d522fbfe67069ddba2d1abfc4f5ca230c26
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CXXC5 SHC4 GAS7 PMEPA1 DST WDR86	1.70e-04	198	183	6	36c97eb71b89bac01cabd6a8b728e5a20e52d2a3
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CXXC5 SHC4 GAS7 PMEPA1 DST WDR86	1.70e-04	198	183	6	50dfe6efca76ea9683a19b6bff59cb5030d346f1
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SPATA18 DRC1 RFX2 RFX3 ADGB EFHC1	1.70e-04	198	183	6	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-Treg\|ICU-NoSEP / Disease, condition lineage and cell class	CDK20 DPH2 ZNF101 ZNF835 ZNF540 SYNE2	1.70e-04	198	183	6	1ed4dfe5565328cb0f7ef31e6b2f67dfbdf3e2ac
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CXXC5 SHC4 GAS7 PMEPA1 DST WDR86	1.70e-04	198	183	6	52ddc1f1ed4ac4c3bac794c90b8feb03e3c221c4
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-Cilia-bearing_cell\|10w / Sample Type, Dataset, Time_group, and Cell type.	SPATA18 DRC1 GRM8 F5 ADGB MAPK15	1.74e-04	199	183	6	2d8ab4aee300c7c4baf662940ce855da2b6d2cae
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPATA18 DRC1 RFX3 ADGB EFHC1 MAPK15	1.74e-04	199	183	6	92fdf6e2f0786ab2ab78126e9131a93794168139
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SPATA18 DRC1 ADGB WDR93 MAPK15 EFCAB12	1.74e-04	199	183	6	2498237b9e895ca4826a3378d9d40989968df72b
ToppCell	Sigmoid-T_cell-Tfh\|Sigmoid / Region, Cell class and subclass	MYH3 ASAH2 HIC2 ZNF101 ZNF354B SORL1	1.74e-04	199	183	6	fa9404a021a015d1d571c324780b6eef2da47c4c
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SPATA18 DRC1 ADGB WDR93 MAPK15 EFCAB12	1.74e-04	199	183	6	542ec45c931b40738df1f3777b00c83be33a514a
ToppCell	proximal-Epithelial-Ciliated\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SPATA18 DRC1 RFX3 ADGB WDR93 MAPK15	1.74e-04	199	183	6	9700f06e51ddca85e482b4f9bd4a79bfcd3cfb76
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	BAZ2B VPS13C NSD3 DST SYNE2 POPDC3	1.74e-04	199	183	6	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	proximal-3-Epithelial-Ciliated\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SPATA18 DRC1 RFX3 ADGB WDR93 MAPK15	1.74e-04	199	183	6	1188afad6fd5f01f9aeba225f611f38b237dd2c9
ToppCell	Sigmoid-(1)_T_cell-(16)_Tfh\|Sigmoid / shred on region, Cell_type, and subtype	MYH3 ASAH2 HIC2 ZNF101 ZNF354B SORL1	1.74e-04	199	183	6	a61bf52d2d359746433623ee00337124f1f84f61
ToppCell	proximal-Epithelial-Ciliated-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SPATA18 DRC1 RFX3 ADGB WDR93 MAPK15	1.74e-04	199	183	6	2e8ace105c4e2405baa06d953e52888b54e2d055
ToppCell	TCGA-Stomach-Primary_Tumor\|TCGA-Stomach / Sample_Type by Project: Shred V9	ENC1 ZNF267 BMP1 NOP58 PDCD11 ATIC	1.74e-04	199	183	6	38f1f612b29feb868322999ceeda78e52447ec4f
Disease	non-alcoholic fatty liver disease, type 2 diabetes mellitus	ATRN HTR1E ATP8A2 SHC4 PTCD1 ADAMTS18	4.97e-05	110	174	6	EFO_0003095, MONDO_0005148
Disease	Cohen syndrome (implicated_via_orthology)	VPS13C VPS13B	1.03e-04	3	174	2	DOID:0111590 (implicated_via_orthology)
Disease	schizophrenia, anorexia nervosa	CUL3 CACNA1C ALMS1 ZNF592	1.86e-04	48	174	4	MONDO_0005090, MONDO_0005351
Disease	Impulsive Petit Mal Epilepsy	EFHC1 JRK	2.06e-04	4	174	2	C4553298
Disease	Juvenile Myoclonic Epilepsy of Janz	EFHC1 JRK	2.06e-04	4	174	2	C4551857
Disease	Myoclonic Epilepsy, Adolescent	EFHC1 JRK	2.06e-04	4	174	2	C4552768
Disease	Myoclonic Epilepsy, Juvenile, 1	EFHC1 JRK	2.06e-04	4	174	2	C4553087
Disease	blood aluminium measurement	DPP6 ZBTB38 BAZ2B	2.13e-04	20	174	3	EFO_0007575
Disease	autosomal recessive limb-girdle muscular dystrophy (is_implicated_in)	HMGCR POPDC3	3.42e-04	5	174	2	DOID:0110274 (is_implicated_in)
Disease	bipolar disorder, anorexia nervosa	CACNA1C ZNF592	5.11e-04	6	174	2	MONDO_0004985, MONDO_0005351
Disease	Akinetic Petit Mal	EFHC1 JRK	7.12e-04	7	174	2	C0001890
Disease	Epilepsy, Absence, Atypical	EFHC1 JRK	7.12e-04	7	174	2	C0751124
Disease	Absence Seizure Disorder	EFHC1 JRK	7.12e-04	7	174	2	C4553705
Disease	Juvenile Absence Epilepsy	EFHC1 JRK	7.12e-04	7	174	2	C4317339
Disease	Childhood Absence Epilepsy	EFHC1 JRK	7.12e-04	7	174	2	C4281785
Disease	Epilepsy, Minor	EFHC1 JRK	7.12e-04	7	174	2	C4552765
Disease	Absence Epilepsy	EFHC1 JRK	7.12e-04	7	174	2	C0014553
Disease	Juvenile Myoclonic Epilepsy	EFHC1 JRK	9.46e-04	8	174	2	C0270853
Disease	Mental deterioration	CACNA1C SORL1	1.21e-03	9	174	2	C0234985
Disease	Mild cognitive disorder	CACNA1C SORL1	1.21e-03	9	174	2	C1270972
Disease	familial melanoma (is_implicated_in)	POT1 CDK4	1.21e-03	9	174	2	DOID:6846 (is_implicated_in)
Disease	Malignant neoplasm of breast	UTS2R ADAMTS1 TRPC4 SPATA18 RFX2 ZNF25 MAP3K1 PIK3R4 BMP1 LIPE LBX1 SYNE2 SLC35A2 VPS13B SORL1	1.81e-03	1074	174	15	C0006142
Disease	polybrominated biphenyl measurement, gestational serum measurement, fetal genotype effect measurement, polybrominated diphenyl ether measurement	LOXHD1 ZFHX3	1.84e-03	11	174	2	EFO_0007959, EFO_0007961, EFO_0007962, EFO_0007964
Disease	Familial Atypical Mole Melanoma Syndrome	POT1 CDK4	1.84e-03	11	174	2	C2314896
Disease	nicotine dependence (implicated_via_orthology)	TRPC4 TRPC5	2.19e-03	12	174	2	DOID:0050742 (implicated_via_orthology)
Disease	methionine sulfone measurement	ALMS1 CEP89	2.19e-03	12	174	2	EFO_0800072
Disease	N-acetyl-2-aminooctanoate measurement	ALMS1 BTD	2.19e-03	12	174	2	EFO_0800567
Disease	Anxiety States, Neurotic	CACNA1C GRM8 CNR1	2.23e-03	44	174	3	C0376280
Disease	Anxiety neurosis (finding)	CACNA1C GRM8 CNR1	2.23e-03	44	174	3	C1279420
Disease	Anxiety Disorders	CACNA1C GRM8 CNR1	2.23e-03	44	174	3	C0003469
Disease	alcohol use disorder measurement, alcohol consumption measurement	CACNA1C DPP6 ZFHX3 SORL1	2.64e-03	97	174	4	EFO_0007878, EFO_0009458
Disease	Impaired cognition	CACNA1C SORL1	3.00e-03	14	174	2	C0338656
Disease	smoking status measurement	CUL3 CACNA1C DPP6 TRPC4 MFSD4B GRM8 RFX3 GK5 PTK2 RYR2 SPTBN4 ALMS1 PTCD1 ZFHX3 SORL1	3.75e-03	1160	174	15	EFO_0006527
Disease	interferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement	F5 MEN1	3.93e-03	16	174	2	EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
Disease	isocitrate measurement	ENC1 TRPM8	3.93e-03	16	174	2	EFO_0010505
Disease	acute graft vs. host disease	CUL3 ZBTB38 PTK2	4.01e-03	54	174	3	EFO_0004599
Disease	Small cell carcinoma of lung	ZDBF2 GRM8 TAOK3	4.01e-03	54	174	3	C0149925
Disease	mental or behavioural disorder	HTR1E VPS13C ATP8A2 SHC4 RFX2	4.27e-03	179	174	5	EFO_0000677
Disease	sphingomyelin 14:0 measurement	SYNE2 ZFHX3	4.44e-03	17	174	2	EFO_0010390
Disease	Ischemic stroke, venous thromboembolism, stroke, Abnormal thrombosis, deep vein thrombosis, pulmonary embolism	TTF2 F5	4.44e-03	17	174	2	EFO_0000712, EFO_0003827, EFO_0003907, EFO_0004286, HP_0001977, HP_0002140
Disease	breast cancer (is_marker_for)	PMEPA1 MAP3K1 MAPK15 ZFHX3 CDK4	4.91e-03	185	174	5	DOID:1612 (is_marker_for)
Disease	Brain Ischemia	IL10RB ASIC1 F5	5.39e-03	60	174	3	C0007786
Disease	Cerebral Ischemia	IL10RB ASIC1 F5	5.39e-03	60	174	3	C0917798

Protein segments in the cluster

Peptide	Gene	Start	Entry
SHRFRQYLKAFLAAV	ACKR2	316	O00590
SSYLLSRARKVLGSH	ERI3	91	O43414
RIAASKALLHQYFFT	CDK20	276	Q8IZL9
RAIKASQARLHYLSG	ADGB	1401	Q8N7X0
YRRKLFDASHSLRSV	BAZ2B	1361	Q9UIF8
FLDASRSSKLLRAFY	ALG9	566	Q9H6U8
QKHQRFYSSLFALVR	ASB10	406	Q8WXI3
SLYQKRGSSRHLSNR	HTR1E	211	P28566
NTTRSVFRSAKFYIH	ALMS1	3471	Q8TCU4
AHLRNLTQAAGKRSY	DPH2	301	Q9BQC3
SLHTRTSKLFQGQYR	ARHGEF7	161	Q14155
LRYTSTKFQDTLHSR	BMP1	971	P13497
HSSYSELRAFVAALK	DCLRE1B	276	Q9H816
RSSLATAREHYILAK	EFCAB12	271	Q6NXP0
RLASSQINKFLYLHT	ATG2A	1531	Q2TAZ0
GHTLKYALSFEVRRS	ATP8A2	766	Q9NTI2
KKRSAQNARSSLHYR	ADAMTS18	86	Q8TE60
FSVAARLYKHPSIRN	ADAMTS1	286	Q9UHI8
LFLSLKASYRLHQLR	INO80	916	Q9ULG1
RSYFKDRAHIQSLFS	MEN1	131	O00255
SSSQNGSYHRIRALK	NUP210	401	Q8TEM1
GLAHSLSRYRLKFSA	NOP58	141	Q9Y2X3
TRSINRDKHLAVAYF	NCF2	61	P19878
LAHYNKRSTITSRRS	H2BC20P	81	Q6DN03
LAHYNKRSTITSRRS	H2BC19P	81	Q6DRA6
LLLNYRKSSRHLAAF	INTS1	1941	Q8N201
SLVKFRSLVHAYVSR	MYO15A	1951	Q9UKN7
SIFYQLLRATRFLHS	MAPK15	116	Q8TD08
RKLDHATDRFRSLYS	DST	4016	Q03001
AFDSTSRFARLQKLH	HMGCR	621	P04035
ARFLRNYIKSSAHTL	LRRC53	226	A6NM62
VARKAALLSRFSDSY	SPATA18	296	Q8TC71
HTLSAYIQLFRNLAK	ASAH2	601	Q9NR71
ILKDSRFFRYLHTAV	ATRN	546	O75882
DSSATLKNFRYHISL	LOXHD1	676	Q8IVV2
LSYQAKRDAHRSLGI	CCNYL2	151	Q5T2Q4
RAHKAQLLRFFASSD	JRK	56	O75564
FSHSYSGLAKRLANI	KIAA1586	506	Q9HCI6
VRKSNRAALHLYSNT	NAA10	111	P41227
LHKFTFANTTSLRYL	LRRC52	141	Q8N7C0
RSKADYTSHLRSLVS	GCN1	2181	Q92616
YKRSAALSQFVIHRS	ATP9A	836	O75110
FSYAALLTKTNRIHR	GRM8	661	O00222
KSLRRSRPLSHYSSF	CXXC5	71	Q7LFL8
LVNFFLKYRAHRLSS	DRC1	546	Q96MC2
TTRLYGLSTFKDARH	EXOC6	581	Q8TAG9
ASAETFRRAKYHNAL	MFSD4B	216	Q5TF39
TYSLFRRKTHLGTQD	MILR1	66	Q7Z6M3
LLSHYKLSARSFISR	PMEPA1	61	Q969W9
ALTEHKVLFLSRSYQ	SBF1	231	O95248
TSNLSHDNRRKYIFS	GRIN3A	1016	Q8TCU5
RTISKLRNETYHVFS	PTPRU	541	Q92729
CSPLQTRRAHFSKYL	PIK3C2B	666	O00750
LKRAVSDLRVTHYFF	PIK3C2B	941	O00750
QKDTFYGLRSLTRLH	IGSF10	121	Q6WRI0
DDYHLRNKTIFLRTS	IFTAP	76	Q86VG3
AASSHRDIYKNARSL	HEATR5B	171	Q9P2D3
SEASRLAHYNKRSTI	H2BU1	76	Q8N257
FRLSYGRVLSHSSKI	ILVBL	356	A1L0T0
YKTRLRSLHFQATLQ	GRID2IP	976	A4D2P6
RSRAVASKIGHSYSL	CARD6	841	Q9BX69
ARLAHRISKSKFSRY	CACNA1C	491	Q13936
ITLYRHQKAAFAITS	BTAF1	971	O14981
HKRISAFRALQHSYL	CDK4	281	P11802
NVELSRYQTKFRHLS	CEP89	326	Q96ST8
SNRLFHKTVYLQSAL	EI24	301	O14681
RFKAHRAILSARSSY	BTBD8	216	Q5XKL5
RRFYLAKHSGRQLTL	CUL3	536	Q13618
SEASRLAHYNKRSTI	H2BC13	76	Q99880
NDHYFLRKSRLSSGL	BTD	516	P43251
IYALRSKDLRHAFRS	CNR1	396	P21554
FSSLSKYGDHTLRVR	IL10RB	76	Q08334
KISRFERHLYNSAAF	IFRD1	416	O00458
SLYLFAKNVRSLLHT	MARF1	1486	Q9Y4F3
TKTAFHRSQTLSYRN	EFHC1	21	Q5JVL4
LHFFTRSKRLFTASL	GK5	146	Q6ZS86
SRASSGSINIYLFHK	ENC1	11	O14682
YLQNTKLTLAHRSFI	ERMARD	221	Q5T6L9
RKSRTAFTNHQIYEL	LBX1	126	P52954
FTSSSLKQHLYRSII	DPP6	826	P42658
KLLAFYSSHSASSLR	HPS1	216	Q92902
ASLSKRRTYAGLAFH	SLC38A10	61	Q9HBR0
KNHRLYFLSAASRPL	RYR2	2976	Q92736
FAQHRYISRLFSVLI	POPDC3	221	Q9HBV1
HLLHKSRYVASNRRS	LIPE	386	Q05469
FTAANVYHLLKRSIS	MTBP	41	Q96DY7
ESLFQKYHSRRSSRI	MAP3K1	386	Q13233
IFRAHKNVLAASSIY	HIC2	56	Q96JB3
VVDKNLRHRSSYFFL	HRH4	41	Q9H3N8
LRHRSSYFFLNLAIS	HRH4	46	Q9H3N8
ASRLQKYFTHARRAQ	RPUSD3	151	Q6P087
KYFTHARRAQRPTAT	RPUSD3	156	Q6P087
AILYTKHRRLQSSFT	SORL1	2156	Q92673
DISSLYAKAQHVARR	TRMT1L	401	Q7Z2T5
RFSLYQTRSLIHELK	SYNE2	5731	Q8WXH0
RESSRGKNTFLYQLH	TDRD9	1361	Q8NDG6
YNTFSERRLKHSLVL	F5	1056	P12259
AFAQTLRRYTSLNHL	RFX2	506	P48378
AFAQTLRRYTSLNHL	RFX3	491	P48380
ARVSQHYKASLTATF	POMGNT1	366	Q8WZA1
STALAYLESKRFVHR	PTK2	531	Q05397
HIADLRKQLASRYAS	GAS7	321	O60861
RSLKVGSFLRIYSLH	POT1	231	Q9NUX5
ALHYRNRERFATIKS	TAOK3	426	Q9H2K8
LGYHASLNRALRTFL	SRGAP2B	281	P0DMP2
QKSSNRLLAHLYATF	MYH3	611	P11055
FYRKSSRKPSSHRNA	SPATA3	156	Q8NHX4
RIHRSLASQFKYALV	DRG2	321	P55039
SVLSYHSSFSIRKSR	ARHGAP35	836	Q9NRY4
SLKESRHRRFSYSQS	SRSF12	136	Q8WXF0
SALQDTFFAKLHRSR	RIPOR2	376	Q9Y4F9
VTLYLAAASKNQHFR	RIPOR2	961	Q9Y4F9
GTASAAHRRLKYISL	SLC35A2	26	P78381
FYAHKVLLVTASNRF	ABTB2	856	Q8N961
AHIFSYERLSLKRAL	ASIC1	31	P78348
YALRSKDITSLFRHL	PIK3R4	731	Q99570
HRAKYSRFRNESITS	SHC4	26	Q6S5L8
LAYARLSHLSDSKNV	PDCD11	391	Q14690
KTFSRASYLVQHSRI	ZNF30	491	P17039
YSARLSIRDHIFSKQ	ZFHX4	2971	Q86UP3
GKTFRLSFYLTEHRR	ZNF540	361	Q8NDQ6
GKTFRYLASLQAHVR	ZNF77	526	Q15935
KAFSYNSSLLVHRRI	ZNF197	741	O14709
RAFASATNYKNHVRI	ZNF143	366	P52747
FSSKSSVIQHQRRYA	ZNF2	406	Q9BSG1
KTFSRGYHLTLHQRI	ZFP30	361	Q9Y2G7
NRTILYQFSRAHKTV	WDFY3	2096	Q8IZQ1
RQHLYSVFDRATSKV	RBP3	806	P10745
SLVTYFRLRGLSVNH	OR4E1	11	P0C645
LTFFSYSLLHASRKT	SLC37A3	26	Q8NCC5
ATLKRLSAFYNTHDL	STAG3	701	Q9UJ98
ILTLRKGANTHYFRD	UBA7	191	P41226
KAFSYSSDVIQHRRI	ZNF267	611	Q14586
GKAFNSRSYLTTHRR	ZNF267	666	Q14586
FALEKSLSQHYGRRS	ZNF592	596	Q92610
KSFCYSSVLLRHERA	ZNF672	21	Q499Z4
YHDLSKFTSVRRDRN	WDR44	816	Q5JSH3
SVFLRHRYQSRSAFL	ZDBF2	2231	Q9HCK1
RSYVTLSSLKRHSNV	ZBTB4	316	Q9P1Z0
DKHAQRFLSRTFALA	THNSL1	26	Q8IYQ7
RAQLLAASRELHKFF	SPTBN4	1826	Q9H254
FKQSSHQRSLRARLY	VPS13C	3191	Q709C8
LTHFSQRYKPVALAR	ELAC1	311	Q9H777
RRQLALKAFTHTAQY	ATIC	171	P31939
LRIKRAHENSVTNFY	NSD3	1186	Q9BZ95
RYILSLSFRSQGITH	SOCS7	431	O14512
HRQKYLASAERAALA	TLX3	186	O43711
KVFSRSSQLQYHRRV	ZNF234	631	Q14588
LRAVQYTEKLHRSSA	TIMM21	6	Q9BVV7
KSFTYNSALRAHQRI	ZNF658	581	Q5TYW1
HRQKYLASAERAALA	TLX1	221	P31314
RAHRAYLTLLFATSI	UTS2R	206	Q9UKP6
LHLKRYSFNVALSLN	USP37	561	Q86T82
KIFYHLSSLSRHLRT	ZNF25	181	P17030
KVFTFSNYLRLHERT	ZNF101	401	Q8IZC7
RSHNFFLYSLNRTLK	WDR93	386	Q6P2C0
KCSFRTRLHFTYENL	VPS13B	231	Q7Z7G8
LSKTHDSSRQRLYNT	ZNF26	116	P17031
KAFSFSSALIRHQRT	ZNF835	481	Q9Y2P0
GLHSSNKRSILRSNY	ZKSCAN2	291	Q63HK3
KFTLRSHYDGIRSLA	STRN4	431	Q9NRL3
KSYSQSSALLQHRRV	ZNF530	526	Q6P9A1
RHSRSRLNIYKALAS	TRPC5	191	Q9UL62
GKAFRLYSFLTQHQR	ZFP14	486	Q9HCL3
TQRDSSLFYHCLKRR	TBX4	326	P57082
NTFKSSSSLRYHQRI	ZNF354A	361	O60765
KRSYVTLSSLRRHAN	ZBTB38	466	Q8NAP3
HLCRKALRSFLTTYQ	WSB2	371	Q9NYS7
RLHSSNKSSLYSGRV	TRPM8	816	Q7Z2W7
NTFKSSSSLRYHQRI	ZNF354B	361	Q96LW1
ASLLSKRSFHYLRSR	UCN3	51	Q969E3
YSSRRLFRKSAAQFH	PTCD1	96	O75127
KTFSNSSYLRPHLRI	ZNF557	236	Q8N988
KNLLRAFYELSQTHR	PICK1	171	Q9NRD5
RNVSALKYHAGTLFT	WDR86	276	Q86TI4
RRISFSASHRLYSKF	PTS	16	Q03393
RYLLSIRLSSHRKHS	TGM6	111	O95932
KFFSRSSDYIAHQRV	ZNF134	351	P52741
RHSRSRLNIYKALAS	TRPC4	191	Q9UBN4
KAFNYSSLLRRHHIT	ZNF816	236	Q0VGE8
RSRSALQSYLKRHES	TTF2	861	Q9UNY4
SLNRHLRAFSYSSSL	ZNF878	116	C9JN71
KHDLNLSQRRRAYST	VWA5B1	646	Q5TIE3
IKYSARLSVRDHIFS	ZFHX3	3031	Q15911
KSFTYNSALRAHQRI	ZNF658B	341	Q4V348
KAFSYQSDLLVHSRI	ZNF391	116	Q9UJN7
RSLVSHNVYIFSLKL	KLHL38	346	Q2WGJ6
FKLARHSSGLQTLTY	KCNF1	301	Q9H3M0
FKAHRAVLAASSLYF	NACC2	41	Q96BF6