Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3K4me/H3K4me2/H3K4me3 demethylase activity	KDM5B KDM5A KDM5C KDM5D	5.25e-09	6	88	4	GO:0034647
GeneOntologyMolecularFunction	histone H3K4 demethylase activity	KDM5B KDM5A KDM5C KDM5D	2.43e-08	8	88	4	GO:0032453
GeneOntologyMolecularFunction	histone H3 demethylase activity	KDM5B KDM5A KDM5C KDM5D	6.65e-06	28	88	4	GO:0141052
GeneOntologyMolecularFunction	2-oxoglutarate-dependent dioxygenase activity	KDM5B PHYH KDM5A KDM5C KDM5D	9.94e-06	65	88	5	GO:0016706
GeneOntologyMolecularFunction	histone demethylase activity	KDM5B KDM5A KDM5C KDM5D	1.01e-05	31	88	4	GO:0032452
GeneOntologyMolecularFunction	protein demethylase activity	KDM5B KDM5A KDM5C KDM5D	1.15e-05	32	88	4	GO:0140457
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	KDM5B PHYH KDM5A MICAL2 KDM5C AKR1C4 KDM5D	2.40e-05	194	88	7	GO:0016705
GeneOntologyMolecularFunction	demethylase activity	KDM5B KDM5A KDM5C KDM5D	4.18e-05	44	88	4	GO:0032451
GeneOntologyMolecularFunction	dioxygenase activity	KDM5B PHYH KDM5A KDM5C KDM5D	7.29e-05	98	88	5	GO:0051213
GeneOntologyMolecularFunction	oxidoreductase activity	KDM5B PHYH AOC1 GAPDH PTGR1 KDM5A MICAL2 KDM5C AKR1C4 HADHA KDM5D NDUFC2	1.32e-04	766	88	12	GO:0016491
GeneOntologyMolecularFunction	neurotrophin receptor activity	NTRK2 NTRK3	1.90e-04	5	88	2	GO:0005030
GeneOntologyMolecularFunction	cyclin binding	GAK PTCH1 HERC6	4.89e-04	35	88	3	GO:0030332
GeneOntologyMolecularFunction	histone modifying activity	KDM5B KDM5A KDM5C MIER3 MECOM KDM5D	5.28e-04	229	88	6	GO:0140993
GeneOntologyMolecularFunction	hyalurononglucosaminidase activity	CEMIP2 CEMIP	6.78e-04	9	88	2	GO:0004415
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	GRIA4 GRIN2B SLC7A14 SLC36A2	1.20e-03	105	88	4	GO:0015171
GeneOntologyMolecularFunction	neurotrophin binding	NTRK2 NTRK3	1.23e-03	12	88	2	GO:0043121
MousePheno	abnormal trigeminal ganglion morphology	NTRK2 NTRK3 HIPK2 MECOM PTCH1	1.17e-05	55	76	5	MP:0001092
MousePheno	small vestibular ganglion	MYO7A NTRK2 NTRK3	2.47e-05	11	76	3	MP:0003987
MousePheno	abnormal glossopharyngeal ganglion morphology	NTRK2 NTRK3 MECOM PTCH1	2.58e-05	32	76	4	MP:0001096
MousePheno	duodenum polyps	AP1M2 SMAD4	8.72e-05	3	76	2	MP:0008012
Domain	Lys_sp_deMease-like_dom	KDM5B KDM5A KDM5C KDM5D	4.82e-10	4	89	4	IPR013637
Domain	PLU-1	KDM5B KDM5A KDM5C KDM5D	4.82e-10	4	89	4	PF08429
Domain	zf-C5HC2	KDM5B KDM5A KDM5C KDM5D	2.40e-09	5	89	4	PF02928
Domain	Znf_C5HC2	KDM5B KDM5A KDM5C KDM5D	2.40e-09	5	89	4	IPR004198
Domain	JmjN	KDM5B KDM5A KDM5C KDM5D	9.90e-08	10	89	4	SM00545
Domain	JmjN	KDM5B KDM5A KDM5C KDM5D	9.90e-08	10	89	4	PF02375
Domain	JMJN	KDM5B KDM5A KDM5C KDM5D	9.90e-08	10	89	4	PS51183
Domain	JmjN	KDM5B KDM5A KDM5C KDM5D	9.90e-08	10	89	4	IPR003349
Domain	-	KDM5B KDM5A KDM5C KDM5D	6.32e-07	15	89	4	1.10.150.60
Domain	BRIGHT	KDM5B KDM5A KDM5C KDM5D	6.32e-07	15	89	4	SM00501
Domain	ARID_dom	KDM5B KDM5A KDM5C KDM5D	6.32e-07	15	89	4	IPR001606
Domain	ARID	KDM5B KDM5A KDM5C KDM5D	6.32e-07	15	89	4	PS51011
Domain	ARID	KDM5B KDM5A KDM5C KDM5D	6.32e-07	15	89	4	PF01388
Domain	JmjC	KDM5B KDM5A KDM5C KDM5D	4.76e-06	24	89	4	PF02373
Domain	JMJC	KDM5B KDM5A KDM5C KDM5D	1.56e-05	32	89	4	PS51184
Domain	JmjC_dom	KDM5B KDM5A KDM5C KDM5D	1.56e-05	32	89	4	IPR003347
Domain	JmjC	KDM5B KDM5A KDM5C KDM5D	1.77e-05	33	89	4	SM00558
Domain	NDUF_C2	NDUFC2-KCTD14 NDUFC2	2.25e-05	2	89	2	PF06374
Domain	NADH-UbQ_OxRdtase_b14.5b_su	NDUFC2-KCTD14 NDUFC2	2.25e-05	2	89	2	IPR009423
Domain	TPKR_C2	NTRK2 NTRK3	6.72e-05	3	89	2	PF16920
Domain	Tyr_kinase_NGF_rcpt	NTRK2 NTRK3	6.72e-05	3	89	2	IPR020777
Domain	NTRK_C2	NTRK2 NTRK3	6.72e-05	3	89	2	IPR031635
Domain	G8_domain	CEMIP2 CEMIP	1.34e-04	4	89	2	IPR019316
Domain	G8	CEMIP2 CEMIP	1.34e-04	4	89	2	PS51484
Domain	G8	CEMIP2 CEMIP	1.34e-04	4	89	2	SM01225
Domain	G8	CEMIP2 CEMIP	1.34e-04	4	89	2	PF10162
Domain	Zinc_finger_PHD-type_CS	KDM5B KDM5A KDM5C KDM5D	2.61e-04	65	89	4	IPR019786
Domain	PHD	KDM5B KDM5A KDM5C KDM5D	4.52e-04	75	89	4	PF00628
Domain	Znf_PHD-finger	KDM5B KDM5A KDM5C KDM5D	5.51e-04	79	89	4	IPR019787
Domain	Pectin_lyase_fold/virulence	CEMIP2 CEMIP	6.17e-04	8	89	2	IPR011050
Domain	Znf_FYVE_PHD	PIKFYVE KDM5B KDM5A KDM5C KDM5D	6.89e-04	147	89	5	IPR011011
Domain	PHD	KDM5B KDM5A KDM5C KDM5D	8.64e-04	89	89	4	SM00249
Domain	Znf_PHD	KDM5B KDM5A KDM5C KDM5D	9.39e-04	91	89	4	IPR001965
Domain	ZF_PHD_2	KDM5B KDM5A KDM5C KDM5D	1.10e-03	95	89	4	PS50016
Domain	ZF_PHD_1	KDM5B KDM5A KDM5C KDM5D	1.15e-03	96	89	4	PS01359
Domain	Tyr_kinase_rcpt_2_CS	NTRK2 NTRK3	1.20e-03	11	89	2	IPR002011
Domain	-	PIKFYVE KDM5B TRAF5 KDM5A KDM5C RNF213 KDM5D TTC3	1.35e-03	449	89	8	3.30.40.10
Domain	RECEPTOR_TYR_KIN_II	NTRK2 NTRK3	1.44e-03	12	89	2	PS00239
Domain	Znf_RING/FYVE/PHD	PIKFYVE KDM5B TRAF5 KDM5A KDM5C RNF213 KDM5D TTC3	1.55e-03	459	89	8	IPR013083
Domain	Lig_chan-Glu_bd	GRIA4 GRIN2B	3.27e-03	18	89	2	PF10613
Domain	Glu/Gly-bd	GRIA4 GRIN2B	3.27e-03	18	89	2	IPR019594
Domain	Lig_chan-Glu_bd	GRIA4 GRIN2B	3.27e-03	18	89	2	SM00918
Domain	Iontro_rcpt	GRIA4 GRIN2B	3.27e-03	18	89	2	IPR001320
Domain	Iono_rcpt_met	GRIA4 GRIN2B	3.27e-03	18	89	2	IPR001508
Domain	Lig_chan	GRIA4 GRIN2B	3.27e-03	18	89	2	PF00060
Domain	PBPe	GRIA4 GRIN2B	3.27e-03	18	89	2	SM00079
Domain	DEP	PIKFYVE DVL2	4.87e-03	22	89	2	PF00610
Domain	DEP	PIKFYVE DVL2	4.87e-03	22	89	2	PS50186
Domain	DEP	PIKFYVE DVL2	4.87e-03	22	89	2	SM00049
Domain	DEP_dom	PIKFYVE DVL2	5.32e-03	23	89	2	IPR000591
Pathway	REACTOME_HDMS_DEMETHYLATE_HISTONES	KDM5B KDM5A KDM5C KDM5D	1.14e-05	29	69	4	MM14934
Pathway	REACTOME_HDMS_DEMETHYLATE_HISTONES	KDM5B KDM5A KDM5C KDM5D	1.02e-04	50	69	4	M27232
Pubmed	Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.	KDM5B KDM5A KDM5C KDM5D	4.01e-11	4	89	4	16541399
Pubmed	Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization.	KDM5B KDM5A KDM5C	1.62e-08	3	89	3	38230606
Pubmed	Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.	KDM5B KDM5A KDM5C	1.62e-08	3	89	3	26645689
Pubmed	Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.	KDM5B KDM5A KDM5C KDM5D	2.81e-08	13	89	4	24619213
Pubmed	TEAD1, MYO7A and NDUFC2 are novel functional genes associated with glucose metabolism in BXD recombinant inbred population.	NDUFC2-KCTD14 MYO7A NDUFC2	6.47e-08	4	89	3	38385898
Pubmed	The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.	KDM5B KDM5C KDM5D	6.47e-08	4	89	3	17320160
Pubmed	Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock.	KDM5B KDM5A KDM5C	3.22e-07	6	89	3	21960634
Pubmed	Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein-induced transcriptional activation.	HIPK2 PTCH1 SMAD4	5.63e-07	7	89	3	12874272
Pubmed	Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-beta signaling.	NTRK2 NTRK3 GRIN2B SMAD4	1.20e-06	31	89	4	21300867
Pubmed	Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.	KDM5B KDM5A KDM5C KDM5D	1.55e-06	33	89	4	26864203
Pubmed	Disorganized innervation and neuronal loss in the inner ear of Slitrk6-deficient mice.	MYO7A NTRK2 NTRK3	5.78e-06	14	89	3	19936227
Pubmed	Abnormal development of pacinian corpuscles in double trkB;trkC knockout mice.	NTRK2 NTRK3	6.48e-06	2	89	2	17101216
Pubmed	Mutations in myosin VIIA (MYO7A) and usherin (USH2A) in Spanish patients with Usher syndrome types I and II, respectively.	MYO7A USH2A	6.48e-06	2	89	2	12112664
Pubmed	Mapping of the tyrosine kinase receptors trkA (NTRK1), trkB (NTRK2) and trkC(NTRK3) to human chromosomes 1q22, 9q22 and 15q25 by fluorescence in situ hybridization.	NTRK2 NTRK3	6.48e-06	2	89	2	9195161
Pubmed	Mice Deficient in Nucleoporin Nup210 Develop Peripheral T Cell Alterations.	NUP210 FOXP3	6.48e-06	2	89	2	30323813
Pubmed	The TrkB-positive dopaminergic neurons are less sensitive to MPTP insult in the substantia nigra of adult C57/BL mice.	NTRK2 NTRK3	6.48e-06	2	89	2	21562748
Pubmed	Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.	KDM5C KDM5D	6.48e-06	2	89	2	10441747
Pubmed	Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.	KDM5C KDM5D	6.48e-06	2	89	2	16416087
Pubmed	Protein Kinase C-η Deficiency Does Not Impair Antiviral Immunity and CD8+ T Cell Activation.	PRKCH FOXP3	6.48e-06	2	89	2	32198145
Pubmed	The role and regulation of TMEM2 (transmembrane protein 2) in HYBID (hyaluronan (HA)-binding protein involved in HA depolymerization/ KIAA1199/CEMIP)-mediated HA depolymerization in human skin fibroblasts.	CEMIP2 CEMIP	6.48e-06	2	89	2	30241936
Pubmed	Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.	KDM5C KDM5D	6.48e-06	2	89	2	32081420
Pubmed	TrkB but not trkC receptors are necessary for postnatal maintenance of hippocampal spines.	NTRK2 NTRK3	6.48e-06	2	89	2	17442456
Pubmed	Concurrent Overexpression of Two Hyaluronidases, KIAA1199 and TMEM2, Strongly Predicts Shorter Survival After Resection in Pancreatic Ductal Adenocarcinoma.	CEMIP2 CEMIP	6.48e-06	2	89	2	36395406
Pubmed	Selective activation and down-regulation of Trk receptors by neurotrophins in human neurons co-expressing TrkB and TrkC.	NTRK2 NTRK3	6.48e-06	2	89	2	35536742
Pubmed	Haploinsufficiency in trkB and/or trkC neurotrophin receptors causes structural alterations in the aged hippocampus and amygdala.	NTRK2 NTRK3	6.48e-06	2	89	2	14622193
Pubmed	Expression and regulation of recently discovered hyaluronidases, HYBID and TMEM2, in chondrocytes from knee osteoarthritic cartilage.	CEMIP2 CEMIP	6.48e-06	2	89	2	36241903
Pubmed	KDM5 lysine demethylases are involved in maintenance of 3'UTR length.	KDM5B KDM5A	6.48e-06	2	89	2	28138513
Pubmed	A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.	KDM5C KDM5D	6.48e-06	2	89	2	7524912
Pubmed	Severe sensory deficits but normal CNS development in newborn mice lacking TrkB and TrkC tyrosine protein kinase receptors.	NTRK2 NTRK3	6.48e-06	2	89	2	9421165
Pubmed	The combined effects of trkB and trkC mutations on the innervation of the inner ear.	NTRK2 NTRK3	6.48e-06	2	89	2	9881298
Pubmed	Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms.	NTRK2 NTRK3	6.48e-06	2	89	2	32315394
Pubmed	MYO7A and USH2A gene sequence variants in Italian patients with Usher syndrome.	MYO7A USH2A	6.48e-06	2	89	2	25558175
Pubmed	Lack of TrkB and TrkC signaling alters the synaptogenesis and maturation of mossy fiber terminals in the hippocampus.	NTRK2 NTRK3	6.48e-06	2	89	2	15726425
Pubmed	Leveraging the Treg-intrinsic CTLA4-PKCη signaling pathway for cancer immunotherapy.	PRKCH FOXP3	6.48e-06	2	89	2	34588224
Pubmed	Alcohol-associated fibrosis in females is mediated by female-specific activation of lysine demethylases KDM5B and KDM5C.	KDM5B KDM5C	6.48e-06	2	89	2	35468265
Pubmed	The Study of a 231 French Patient Cohort Significantly Extends the Mutational Spectrum of the Two Major Usher Genes MYO7A and USH2A.	MYO7A USH2A	6.48e-06	2	89	2	34948090
Pubmed	KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.	KDM5B KDM5A	6.48e-06	2	89	2	30472020
Pubmed	Protein kinase C-η controls CTLA-4-mediated regulatory T cell function.	PRKCH FOXP3	6.48e-06	2	89	2	24705298
Pubmed	Tropomyosin receptor kinases B and C are tumor progressive and metastatic marker in colorectal carcinoma.	NTRK2 NTRK3	6.48e-06	2	89	2	23332094
Pubmed	Medulloblastoma tumorigenesis diverges from cerebellar granule cell differentiation in patched heterozygous mice.	NTRK3 PTCH1	6.48e-06	2	89	2	14568546
Pubmed	KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance.	KDM5B KDM5A	6.48e-06	2	89	2	34184733
Pubmed	Conditional deletion of TrkC does not modify limbic epileptogenesis.	NTRK2 NTRK3	6.48e-06	2	89	2	22980123
Pubmed	Characterisation of microvascular abnormalities using OCT angiography in patients with biallelic variants in USH2A and MYO7A.	MYO7A USH2A	6.48e-06	2	89	2	31266775
Pubmed	Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis.	KDM5B KDM5A	6.48e-06	2	89	2	36509829
Pubmed	Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.	KDM5C KDM5D	6.48e-06	2	89	2	9060413
Pubmed	Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons.	NTRK2 NTRK3	6.48e-06	2	89	2	11877382
Pubmed	CLINICAL PRESENTATION AND DISEASE COURSE OF USHER SYNDROME BECAUSE OF MUTATIONS IN MYO7A OR USH2A.	MYO7A USH2A	6.48e-06	2	89	2	27828912
Pubmed	Frequent mutations in the neurotrophic tyrosine receptor kinase gene family in large cell neuroendocrine carcinoma of the lung.	NTRK2 NTRK3	6.48e-06	2	89	2	18293376
Pubmed	Developing inner ear sensory neurons require TrkB and TrkC receptors for innervation of their peripheral targets.	NTRK2 NTRK3	6.48e-06	2	89	2	7588071
Pubmed	Novel mutations in MYO7A and USH2A in Usher syndrome.	MYO7A USH2A	6.48e-06	2	89	2	15823922
Pubmed	NDUFC2 deficiency exacerbates endothelial mesenchymal transformation during ischemia-reperfusion via NLRP3.	NDUFC2-KCTD14 NDUFC2	6.48e-06	2	89	2	37506315
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	KDM5B KDM5A KDM5C KDM5D	7.77e-06	49	89	4	34368113
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	KDM5B TRAF5 RGSL1 NRDC GRIA4 LBP HERC6 TTC3 IFI16 IL1RL2	1.05e-05	686	89	10	29987050
Pubmed	Multiple lineage-specific roles of Smad4 during neural crest development.	NTRK2 NTRK3 SMAD4	1.29e-05	18	89	3	19361496
Pubmed	New nomenclature for chromatin-modifying enzymes.	KDM5B KDM5A KDM5C KDM5D	1.43e-05	57	89	4	18022353
Pubmed	The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3.	KDM5B KDM5A KDM5C	1.79e-05	20	89	3	23637629
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	SEMA3F NDUFC2-KCTD14 HSP90B1 GAK GAPDH LPCAT3 XXYLT1 RNF213 HADHA SEC63 PRPF8 ADAR NDUFC2 SMAD4	1.85e-05	1451	89	14	30550785
Pubmed	Survival of inner ear sensory neurons in trk mutant mice.	NTRK2 NTRK3	1.94e-05	3	89	2	9232598
Pubmed	Gangliosides activate Trk receptors by inducing the release of neurotrophins.	NTRK2 NTRK3	1.94e-05	3	89	2	12388556
Pubmed	The Genetics of Usher Syndrome in the Israeli and Palestinian Populations.	MYO7A USH2A	1.94e-05	3	89	2	29490346
Pubmed	RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3.	KDM5A KDM5C	1.94e-05	3	89	2	17320161
Pubmed	The Effects of IGF-1 on Trk Expressing DRG Neurons with HIV-gp120- Induced Neurotoxicity.	NTRK2 NTRK3	1.94e-05	3	89	2	26652865
Pubmed	KDM5 family of demethylases promotes CD44-mediated chemoresistance in pancreatic adenocarcinomas.	KDM5A KDM5C	1.94e-05	3	89	2	37880235
Pubmed	The development of myelinated nociceptors is dependent upon trks in the trigeminal ganglion.	NTRK2 NTRK3	1.94e-05	3	89	2	15530548
Pubmed	Dok5 is substrate of TrkB and TrkC receptors and involved in neurotrophin induced MAPK activation.	NTRK2 NTRK3	1.94e-05	3	89	2	16647839
Pubmed	TrkB and TrkC agonist antibodies improve function, electrophysiologic and pathologic features in Trembler J mice.	NTRK2 NTRK3	1.94e-05	3	89	2	20553714
Pubmed	Developmental dependency of Merkel endings on trks in the palate.	NTRK2 NTRK3	1.94e-05	3	89	2	11295244
Pubmed	Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours.	NTRK2 NTRK3	1.94e-05	3	89	2	21552290
Pubmed	TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons.	NTRK2 NTRK3	1.94e-05	3	89	2	8918886
Pubmed	Trk receptor expression and inhibition in neuroblastomas.	NTRK2 NTRK3	1.94e-05	3	89	2	19417027
Pubmed	Prognostic value of tropomyosin-related kinases A, B, and C in gastric cancer.	NTRK2 NTRK3	1.94e-05	3	89	2	26459250
Pubmed	The Trk tyrosine kinase inhibitor K252a regulates growth of lung adenocarcinomas.	NTRK2 NTRK3	1.94e-05	3	89	2	16862449
Pubmed	NeuroD regulates neuronal migration.	NTRK2 NTRK3	1.94e-05	3	89	2	23652629
Pubmed	Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins.	NTRK2 NTRK3	1.94e-05	3	89	2	7823156
Pubmed	Re-expression of the retinoblastoma-binding protein 2-homolog 1 reveals tumor-suppressive functions in highly metastatic melanoma cells.	KDM5B KDM5A	1.94e-05	3	89	2	16645588
Pubmed	ESMO recommendations on the standard methods to detect NTRK fusions in daily practice and clinical research.	NTRK2 NTRK3	1.94e-05	3	89	2	31268127
Pubmed	NTRK fusion analysis reveals enrichment in Middle Eastern BRAF wild-type PTC.	NTRK2 NTRK3	1.94e-05	3	89	2	33524004
Pubmed	GPC3 and PEG10 peptides associated with placental gp96 elicit specific T cell immunity against hepatocellular carcinoma.	HSP90B1 PEG10	1.94e-05	3	89	2	37932427
Pubmed	Dimerization of the Trk receptors in the plasma membrane: effects of their cognate ligands.	NTRK2 NTRK3	1.94e-05	3	89	2	30366959
Pubmed	Identification of a mouse male-specific transplantation antigen, H-Y.	KDM5C KDM5D	1.94e-05	3	89	2	7544442
Pubmed	Next-generation sequencing to solve complex inherited retinal dystrophy: A case series of multiple genes contributing to disease in extended families.	PRPF8 USH2A	1.94e-05	3	89	2	28761320
Pubmed	TRK Fusions Are Enriched in Cancers with Uncommon Histologies and the Absence of Canonical Driver Mutations.	NTRK2 NTRK3	1.94e-05	3	89	2	31871300
Pubmed	Developmental dependency of Meissner corpuscles on trkB but not trkA or trkC.	NTRK2 NTRK3	1.94e-05	3	89	2	10674466
Pubmed	Expression of mRNAs for neurotrophic factors (NGF, BDNF, NT-3, and GDNF) and their receptors (p75NGFR, trkA, trkB, and trkC) in the adult human peripheral nervous system and nonneural tissues.	NTRK2 NTRK3	1.94e-05	3	89	2	8895847
Pubmed	Gene expression of TRK neurotrophin receptors in advanced neuroblastomas in Singapore--a pilot study.	NTRK2 NTRK3	1.94e-05	3	89	2	21728718
Pubmed	Neurotrophin actions during the development of the peripheral nervous system.	NTRK2 NTRK3	1.94e-05	3	89	2	10383116
Pubmed	Pan-Trk Immunohistochemistry Is an Efficient and Reliable Screen for the Detection of NTRK Fusions.	NTRK2 NTRK3	1.94e-05	3	89	2	28719467
Pubmed	DNA methylation-dependent regulation of TrkA, TrkB, and TrkC genes in human hepatocellular carcinoma.	NTRK2 NTRK3	1.94e-05	3	89	2	21295543
Pubmed	Targeted next generation sequencing in Italian patients with Usher syndrome: phenotype-genotype correlations.	MYO7A USH2A	1.94e-05	3	89	2	29142287
Pubmed	Structural analysis of human KDM5B guides histone demethylase inhibitor development.	KDM5B KDM5C	1.94e-05	3	89	2	27214403
Pubmed	A chemical-genetic approach to studying neurotrophin signaling.	NTRK2 NTRK3	1.94e-05	3	89	2	15820690
Pubmed	FOXP3 orchestrates H4K16 acetylation and H3K4 trimethylation for activation of multiple genes by recruiting MOF and causing displacement of PLU-1.	KDM5B FOXP3	1.94e-05	3	89	2	22152480
Pubmed	Human TMEM2 is not a catalytic hyaluronidase, but a regulator of hyaluronan metabolism via HYBID (KIAA1199/CEMIP) and HAS2 expression.	CEMIP2 CEMIP	1.94e-05	3	89	2	37196767
Pubmed	Crystal Structures of Neurotrophin Receptors Kinase Domain.	NTRK2 NTRK3	1.94e-05	3	89	2	28215291
Pubmed	Differential effects of combined trk receptor mutations on dorsal root ganglion and inner ear sensory neurons.	NTRK2 NTRK3	1.94e-05	3	89	2	8575307
Pubmed	The trk family of tyrosine protein kinase receptors.	NTRK2 NTRK3	1.94e-05	3	89	2	1751544
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KDM5B KDM5A KDM5C	2.08e-05	21	89	3	27626377
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	HSP90B1 GAK NRDC GAPDH PEG10 NUP210 XXYLT1 HADHA SEC63 PRPF8 ADAR PALLD ALPP	2.57e-05	1297	89	13	33545068
Pubmed	Neurotrophin receptors: a window into neuronal differentiation.	NTRK2 NTRK3	3.87e-05	4	89	2	1327010
Pubmed	Amyloid-β Receptors: The Good, the Bad, and the Prion Protein.	GRIA4 GRIN2B	3.87e-05	4	89	2	26719327
Cytoband	3q26.2	ACTRT3 MECOM SLC7A14	1.99e-05	27	89	3	3q26.2
Cytoband	12p11	SINHCAF KDM5A	1.33e-04	9	89	2	12p11
GeneFamily	AT-rich interaction domain containing	KDM5B KDM5A KDM5C KDM5D	1.27e-07	15	58	4	418
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM5B KDM5A KDM5C KDM5D	9.66e-07	24	58	4	485
GeneFamily	PHD finger proteins	KDM5B KDM5A KDM5C KDM5D	1.98e-04	90	58	4	88
Coexpression	MARSON_BOUND_BY_FOXP3_STIMULATED	PIKFYVE KDM5B HSP90B1 CROT NRDC ACTRT3 KDM5A KDM5C NUP210 ZC3H12D FBRS AKR1C4 HADHA IFI16	7.68e-06	1024	88	14	M1742
Coexpression	MARSON_BOUND_BY_FOXP3_STIMULATED	PIKFYVE KDM5B HSP90B1 CROT NRDC ACTRT3 KDM5A KDM5C NUP210 ZC3H12D FBRS AKR1C4 HADHA IFI16	1.29e-05	1072	88	14	MM1031
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500	PTGR1 MICAL2 FAT3 RNF213 GRIA4 KDM5D PTCH1 IL1RL2 PALLD	2.01e-05	364	88	9	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1B RGSL1 FAT3 NTRK3 ATP13A5 GRIN2B USH2A	3.70e-08	162	89	7	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	RNF213 PRKCH PTCH1 HERC6 IFI16 ADAR PALLD	1.56e-07	200	89	7	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1B FAT3 ATP13A5 GRIA4 GRIN2B USH2A	8.38e-07	160	89	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1B FAT3 ATP13A5 GRIA4 GRIN2B USH2A	8.38e-07	160	89	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1B AKAP4 FAT3 GRIN2B SLC7A14 SLC36A2	2.01e-06	186	89	6	bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KDM5A NUP210 RNF213 PRKCH KDM5D CEMIP2	2.64e-06	195	89	6	83c125223e7ca0f08a31414b3a16347912564765
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B CELF4 MICAL2 NTRK2 GRIN2B TTC3	2.89e-06	198	89	6	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	CV-Severe-1\|CV / Virus stimulation, Condition and Cluster	HSP90B1 GAPDH RNF213 HERC6 IFI16 ADAR	2.89e-06	198	89	6	fc0e885e370ffb780eada62bb2b52065c2f8b26b
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1B RGSL1 ATP13A5 GRIN2B USH2A	1.08e-05	145	89	5	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Serous_adenocarcinoma-3\|TCGA-Endometrium / Sample_Type by Project: Shred V9	GUCA1C AOC1 RNF213 LBP SLC36A2	1.59e-05	157	89	5	ef70abc999be3a2c1eed7d21aef4b484f69d8567
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_macrophage-Langerhans_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MICAL2 GNA12 IL1RN IL1RL2 PPP4R4	1.59e-05	157	89	5	10341ed8cbee0f636770a82cf580f6453bee8596
ToppCell	droplet-Lung-nan-3m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KBTBD8 XXYLT1 MED12L IL1RL2 SLC7A14	1.74e-05	160	89	5	8a7a73b0ee1877fe02d47f745d36ae2858b529e1
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	MYO7A ZC3H12D RHBDL1 CEMIP FOXP3	1.91e-05	163	89	5	bca9abd02ffb2a90c8386a59f5e25126ae7b6acd
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	SPTLC3 SPEF1 FAT3 MED12L CEMIP	2.02e-05	165	89	5	7b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	AOC1 PTGR1 KDM5C ZC3H12D TTC3	2.14e-05	167	89	5	ced6ed9b412739c6ced622523347c10295edbf53
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPEF1 NTRK3 XXYLT1 KDM5D PALLD	2.40e-05	171	89	5	d1e87478d8c0329e662849823f5c7604f20e1b1a
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	KDM5A MICAL2 ZC3H12D RNF213 FOXP3	3.15e-05	181	89	5	b193f3606554adc55c5906219d114288bb1f978a
ToppCell	PBMC-Mild-cDC_9\|Mild / Compartment, Disease Groups and Clusters	CACNA1B HSP90B1 PEG10 RNF213 ADAR	3.40e-05	184	89	5	2e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CACNA1B CELF4 NAPG GRIN2B TTC3	3.59e-05	186	89	5	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	KDM5A MICAL2 ZC3H12D RNF213 FOXP3	3.68e-05	187	89	5	689b3cc76f1e04bd35a7d3ce19e9f08744a7835b
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	KDM5A MICAL2 ZC3H12D RNF213 FOXP3	3.68e-05	187	89	5	4527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	KDM5B NRDC IL1RN CEMIP2 FOXP3	3.87e-05	189	89	5	99b01893da9f9f7c9528afaffad178285211738b
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CACNA1B SPTLC3 TRAF5 GRIA4 PTCH1	3.87e-05	189	89	5	0abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CACNA1B CELF4 GRIN2B TTC3 SLC7A14	3.97e-05	190	89	5	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	tumor_Lung-T/NK_cells-Exhausted_Tfh\|tumor_Lung / Location, Cell class and cell subclass	RASAL3 GAPDH MYO7A NTRK2 CEMIP2	4.07e-05	191	89	5	3e259eba83f8159d1a1a96b98d0e867fe547c5e7
ToppCell	CV-Healthy-1\|Healthy / Virus stimulation, Condition and Cluster	GAPDH RNF213 HERC6 IFI16 ADAR	4.17e-05	192	89	5	2a2052b44e8f679ef484f03ba4fb37b0ec841b88
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-Treg\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MICAL2 ZC3H12D RNF213 PRKCH FOXP3	4.17e-05	192	89	5	b7e08cadb50f66c2efdde45e0fa8bab29367269b
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RASAL3 RNF213 PRKCH HERC6 IFI16	4.27e-05	193	89	5	fce4f805e53669acb4c188f87ac7d84408c0c218
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RASAL3 RNF213 PRKCH HERC6 IFI16	4.27e-05	193	89	5	6e1498153a7766c03fddbda1701dbf1596d21736
ToppCell	Hippocampus-Neuronal\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CACNA1B CELF4 NAPG GRIN2B TTC3	4.38e-05	194	89	5	8aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell	control-Myeloid-Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RNF213 HERC6 IFI16 IL1RN ADAR	4.38e-05	194	89	5	267e213e8efe53aadfe553a2ca010a0e3b4b8939
ToppCell	mild-Myeloid-Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RNF213 HERC6 IFI16 IL1RN ADAR	4.60e-05	196	89	5	ded44b38ea489946e9eedfe752b5a9fde9149c16
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1B NTRK2 GRIA4 USH2A SLC7A14	4.60e-05	196	89	5	4bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCell	moderate-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	HSP90B1 HIPK2 RNF213 PRKCH CEMIP2	4.60e-05	196	89	5	9152f4a8a27ff4ee28f231c5ad00eb2edd9ea6da
ToppCell	PBMC-Control-cDC_3\|Control / Compartment, Disease Groups and Clusters	HSP90B1 KDM5A NUP210 HADHA ADAR	4.60e-05	196	89	5	09d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCell	CV-Severe-1\|Severe / Virus stimulation, Condition and Cluster	GAPDH RNF213 HERC6 IFI16 ADAR	4.83e-05	198	89	5	9b9ee0b0f6cc92e7be94869604c98f43d57ff8ff
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B CELF4 MICAL2 GRIN2B TTC3	4.83e-05	198	89	5	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B CELF4 MICAL2 NTRK2 GRIN2B	4.83e-05	198	89	5	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	COVID_non-vent-Lymphocytic-ILC\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	HIPK2 RNF213 PRKCH PTCH1 PALLD	4.94e-05	199	89	5	df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	FAT3 SEC63 TTC3 IFI16 PALLD	4.94e-05	199	89	5	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	COVID_non-vent-Lymphocytic-ILC-NK_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	HIPK2 RNF213 PRKCH PTCH1 PALLD	4.94e-05	199	89	5	ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCell	Bronchus_Control_(B.)-Immune-TX-T_cells\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	RASAL3 ZC3H12D RNF213 PRKCH FOXP3	4.94e-05	199	89	5	cb4cd42e608126227cbbf2342486550bcd4d0fc9
ToppCell	(05)_Secretory-(2)_GFP_FOXI1\|(05)_Secretory / shred by cell type by condition	SBNO1 HIPK2 OSBPL10 NAPG TTC3	4.94e-05	199	89	5	d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell	megakaryocytic-CD34+_Megakaryoblast\|megakaryocytic / Lineage and Cell class	HSP90B1 MED12L HADHA SEC63 TTC3	4.94e-05	199	89	5	99a65887d3c8a2cde26693dd74404b101bba9d58
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	RNF213 PRKCH IFI16 ADAR CEMIP2	5.06e-05	200	89	5	2d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-gd_T\|ICU-NoSEP / Disease, condition lineage and cell class	RASAL3 PEG10 AP1M2 PRKCH PTCH1	5.06e-05	200	89	5	2c2cea7691c340912f6ad77667a580a071eaeb8b
ToppCell	LPS-IL1RA-Endothelial-Mes-Like\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTRK3 USH2A PALLD RASD2	8.94e-05	117	89	4	5a23770806b4612bed4ae6fd716abdec7f7f56c6
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SPTLC3 OSBPL10 NDUFC2 RASD2	1.69e-04	138	89	4	a88c3ae56b0af60f6e87cabade4f21e2bbb336f2
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	SEMA3F SPEF1 PDE8B XXYLT1	2.10e-04	146	89	4	5b2608b56204dda9a773988f42ff00a9fa743a39
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPEF1 ZC3H12D MECOM GRIN2B	2.15e-04	147	89	4	2885978bcfc5623967c0c1204dadf5c78c74a082
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM GRIA4 GRIN2B IL1RN	2.15e-04	147	89	4	b66ccc710b3c04f6fc7fed69f3c892fc110e98fc
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1B GRIA4 GRIN2B USH2A	2.21e-04	148	89	4	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-MPP_myeloid\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	KDM5B FAM86B2 RHBDL1 MECOM	2.33e-04	150	89	4	040468880f69b050c7e992749a165280eb6e61ef
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTRK2 MIER3 FBRS AK9	2.57e-04	154	89	4	16fdafb5c64d2db321554f87129a962d113f1668
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1B FAT3 CEMIP2 CEMIP	2.63e-04	155	89	4	8fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	ZC3H12D RNF213 PRKCH CEMIP2	2.70e-04	156	89	4	1545169694f686d28648a68b552c2ae606599d66
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CACNA1B FAT3 HIPK2 PTCH1	2.77e-04	157	89	4	b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tregs\|GI_small-bowel / Manually curated celltypes from each tissue	NTRK2 NTRK3 IL1RL2 FOXP3	2.77e-04	157	89	4	c44bd530e396b08f16f284e185dcb830843959ea
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRAF5 RASAL3 NUP210 KDM5D	3.04e-04	161	89	4	d72c572613f8eff3251cb7b1e9dcc76d193b2f21
ToppCell	T_cells-Tph_and_Tfh\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	MYO7A ZC3H12D PRKCH CEMIP2	3.12e-04	162	89	4	146058f2d60846376078916055d08f68562e3a7c
ToppCell	T_cells-TFH-like_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	MYO7A NTRK3 ZC3H12D FOXP3	3.26e-04	164	89	4	b10cf59f4cc37ca6cd0ecf71d7de278cc2bdd8b5
ToppCell	droplet-Lung-nan-3m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SINHCAF MED12L PALLD FOXP3	3.26e-04	164	89	4	78de403446fe0eb375c82ff1832cc5fbb8e20afa
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	CELF4 NTRK3 GRIN2B IL1RL2	3.34e-04	165	89	4	9795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	KDM5B FAT3 MED12L PALLD	3.50e-04	167	89	4	cb396f3edb9e8fdc316091e8e193dbba50e0be0c
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NTRK2 OSBPL10 KDM5D HERC6	3.58e-04	168	89	4	5e721268f0baa51d3f640f7f4c41db769ebef210
ToppCell	Control-T_cells-Tregs\|Control / group, cell type (main and fine annotations)	ZC3H12D PRKCH IFI16 FOXP3	3.66e-04	169	89	4	e1e0983f31ec81b3fad5f9c6140d17f03f81a5dc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CELF4 PDE8B PRKCH HERC6	3.66e-04	169	89	4	987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE8B PLEKHA3 IL1RN RASD2	3.66e-04	169	89	4	780fb0050852626062a729dd1b82b0cf61e7e9ca
ToppCell	metastatic_Lymph_Node-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	KDM5B GAPDH MYO7A NTRK2	3.66e-04	169	89	4	3d48acea7482bbe5bb9da4c3af5f9b0c9800122f
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 ATP13A5 GRIA4 USH2A	3.66e-04	169	89	4	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SEMA3F CACNA1B CROT PTCH1	3.74e-04	170	89	4	fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCell	Mild-Treg\|World / Disease group and Cell class	SPEF1 IL1RN IL1RL2 FOXP3	3.74e-04	170	89	4	f3f177534badca34e1ae8671b7f583ee6688e14b
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 NTRK3 GRIA4 PALLD	3.74e-04	170	89	4	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	normal-na-Lymphocytic_T-T4_em-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	NTRK2 ZC3H12D KDM5D ALPP	3.82e-04	171	89	4	61318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell	facs-Liver-Non-hepatocytes-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASAL3 ZC3H12D RASD2 FOXP3	3.91e-04	172	89	4	b440184f2d98d2f2d59566795f44fb79c0647ca4
ToppCell	droplet-Fat-Mat-18m-Lymphocytic-lymphocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTRT3 NUP210 ZC3H12D FOXP3	3.91e-04	172	89	4	226de1a5d4a360d3ae01b0235fea19521ec623a0
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LBP KDM5D PPP4R4 CEMIP2	3.91e-04	172	89	4	f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTGR1 NTRK3 MED12L HIPK2	3.91e-04	172	89	4	ebeda7ef181cac0109be750a98e7589c615d2724
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GAPDH ZC3H12D CEMIP2 FOXP3	3.91e-04	172	89	4	eee45759284baa3ed77da6a5fbcc4f8f6c553106
ToppCell	facs-Heart-LV-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LBP KDM5D PPP4R4 CEMIP2	3.91e-04	172	89	4	6ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF5 RASAL3 ZC3H12D FOXP3	3.91e-04	172	89	4	33c201aaa98acbf1901b6fa6ce0d3ff8012a4d94
ToppCell	Influenza_Severe-B_intermediate\|Influenza_Severe / Disease group and Cell class	NTRK2 ZC3H12D MED12L OSBPL10	4.08e-04	174	89	4	4276bdaac53aebd3084323a90ecde572d3177446
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Natural_Killer_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASAL3 ACTRT3 PRKCH RASD2	4.26e-04	176	89	4	e2b4be7d4f31a78d7862c0fd629dd9cc84589193
ToppCell	droplet-Kidney-nan-18m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NTRK3 XXYLT1 PPP4R4 RASD2	4.26e-04	176	89	4	533d544852038c0612aacf87f4b1c88ff7aace82
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-mature_NK_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASAL3 ACTRT3 PRKCH RASD2	4.26e-04	176	89	4	299075e65ca86564e1c0b06058bd4371a60a3bcd
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	HSP90B1 ACTRT3 RNF213 CEMIP2	4.26e-04	176	89	4	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HSP90B1 MYO7A KBTBD8 IL1RN	4.36e-04	177	89	4	67cc3a6461db5e0678f96b18224aeb83ad34b0f4
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RASAL3 PEG10 NTRK2 NTRK3	4.36e-04	177	89	4	30f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCell	BAL-Control-cDC_1\|Control / Compartment, Disease Groups and Clusters	RNF213 HERC6 IFI16 ADAR	4.36e-04	177	89	4	aa021f6d62e9d740c5ea499faaf875de835a2865
ToppCell	NS-moderate-d_16-33-Lymphoid-B_cell\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PIKFYVE TRAF5 KBTBD8 ZC3H12D	4.36e-04	177	89	4	320fd77c7c98e9305dcc34a168ec9d674539ed65
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CROT FAT3 MED12L PPP4R4	4.45e-04	178	89	4	ccea3c8908d72f5fecd151a133048c8e9758304c
ToppCell	Mild-Treg\|Mild / Disease group and Cell class	KBTBD8 IL1RN IL1RL2 FOXP3	4.45e-04	178	89	4	e669fd95278e145f55126d0e6be8fb2d6184dbbd
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	RNF213 HERC6 IFI16 IL1RN	4.54e-04	179	89	4	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	COVID-19-Heart-VSMC\|Heart / Disease (COVID-19 only), tissue and cell type	TRAF5 NTRK2 NTRK3 HIPK2	4.54e-04	179	89	4	a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3F GAK HIPK2 PRKCH	4.64e-04	180	89	4	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	Children_(3_yrs)-Immune-B_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRAF5 NUP210 ZC3H12D OSBPL10	4.64e-04	180	89	4	40a12eb852373ae3d7c8d9bca376b0ae99f724b3
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_RORB_CARTPT\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRAF5 CROT MED12L PPP4R4	4.64e-04	180	89	4	5e78b29fa1cbdcf502fee3577e5b45766b90d1dc
ToppCell	10x5'-Lung-Myeloid_Dendritic-migDC\|Lung / Manually curated celltypes from each tissue	SPTLC3 SINHCAF AOC1 PALLD	4.64e-04	180	89	4	e9e8992deb0beeee5548910e4616e7c990763d99
ToppCell	Adult-Immune-natural_killer_cell-D175\|Adult / Lineage, Cell type, age group and donor	TRAF5 RASAL3 NUP210 PRKCH	4.64e-04	180	89	4	fc59e28f39e7d4fb1bcc7205202cf39224b70d7b
ToppCell	COPD-Lymphoid-T_Regulatory\|World / Disease state, Lineage and Cell class	ZC3H12D PRKCH CEMIP2 FOXP3	4.64e-04	180	89	4	51a12fbad5fa7bb12e6d616a02ff9b5141e2b063
Drug	Theophylline monohydrate [5967-84-0]; Up 200; 20.2uM; PC3; HT_HG-U133A	NTRK3 GRIN2B IFI16 IL1RN PPP4R4 CEMIP2 SMAD4 CEMIP	1.10e-06	198	89	8	4228_UP
Drug	Tetracycline	SPTLC3 HSP90B1 TRAF5 CROT CUEDC2 NRDC GAPDH GLB1L DVL2 HADHA LBP PALLD PHIP	1.93e-06	668	89	13	ctd:D013752
Drug	K00077	PIKFYVE AKAP4 NTRK2 NTRK3 MECOM GRIA4 PRKCH GRIN2B	2.41e-06	220	89	8	CID006419759
Disease	syndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)	KDM5B KDM5A KDM5C KDM5D	7.38e-11	4	88	4	DOID:0060809 (implicated_via_orthology)
Disease	syndromic intellectual disability (implicated_via_orthology)	KDM5B KDM5A KDM5C KDM5D	1.31e-07	16	88	4	DOID:0050888 (implicated_via_orthology)
Disease	alcohol use disorder (implicated_via_orthology)	KDM5B KDM5A KDM5C FBRS RHBDL1 PRKCH KDM5D	2.00e-06	195	88	7	DOID:1574 (implicated_via_orthology)
Disease	Usher syndrome type 2	MYO7A USH2A	2.63e-05	3	88	2	C0339534
Disease	Usher syndrome (is_implicated_in)	MYO7A USH2A	5.26e-05	4	88	2	DOID:0050439 (is_implicated_in)
Disease	intellectual disability (implicated_via_orthology)	KDM5B KDM5A KDM5C KDM5D	7.64e-05	75	88	4	DOID:1059 (implicated_via_orthology)
Disease	Usher Syndrome, Type II	MYO7A USH2A	8.74e-05	5	88	2	C1568249
Disease	Bipolar Disorder	CACNA1B HSP90B1 NTRK2 NAPG AKR1C4 GRIN2B IL1RN FOXP3	9.13e-05	477	88	8	C0005586
Disease	Human papillomavirus infectious disease (is_implicated_in)	ADAR FOXP3	1.31e-04	6	88	2	DOID:11166 (is_implicated_in)
Disease	response to iloperidone	CELF4 PALLD	1.31e-04	6	88	2	GO_0036287
Disease	Dysthymic Disorder	NTRK2 IL1RN	1.31e-04	6	88	2	C0013415
Disease	Alcoholic Intoxication, Chronic	NRDC GAPDH NTRK2 AKR1C4 GRIN2B IL1RN	1.54e-04	268	88	6	C0001973
Disease	attention deficit hyperactivity disorder (biomarker_via_orthology)	NTRK2 GRIN2B	1.83e-04	7	88	2	DOID:1094 (biomarker_via_orthology)
Disease	Pancreatic carcinoma, familial	PALLD SMAD4	3.12e-04	9	88	2	C2931038
Disease	transcription factor IIIb 90 kda subunit measurement	PIKFYVE LBP	3.90e-04	10	88	2	EFO_0020778
Disease	hyperglycemia (is_marker_for)	PTCH1 IL1RN	6.71e-04	13	88	2	DOID:4195 (is_marker_for)
Disease	Profound Mental Retardation	KDM5A KDM5C GRIN2B PHIP	8.09e-04	139	88	4	C0020796
Disease	Mental Retardation, Psychosocial	KDM5A KDM5C GRIN2B PHIP	8.09e-04	139	88	4	C0025363
Disease	Mental deficiency	KDM5A KDM5C GRIN2B PHIP	8.09e-04	139	88	4	C0917816
Disease	pancreatic ductal carcinoma (is_marker_for)	NTRK3 PALLD SMAD4	8.14e-04	61	88	3	DOID:3587 (is_marker_for)
Disease	schizophrenia (biomarker_via_orthology)	KDM5C GRIN2B	9.00e-04	15	88	2	DOID:5419 (biomarker_via_orthology)
Disease	neurodegenerative disease (implicated_via_orthology)	NRDC DVL2 GRIA4 PTCH1	9.47e-04	145	88	4	DOID:1289 (implicated_via_orthology)
Disease	Grand Mal Status Epilepticus	NTRK2 NTRK3 IL1RN	1.07e-03	67	88	3	C0311335
Disease	Status Epilepticus, Subclinical	NTRK2 NTRK3 IL1RN	1.07e-03	67	88	3	C0751522
Disease	Simple Partial Status Epilepticus	NTRK2 NTRK3 IL1RN	1.07e-03	67	88	3	C0751524
Disease	Non-Convulsive Status Epilepticus	NTRK2 NTRK3 IL1RN	1.07e-03	67	88	3	C0751523
Disease	Petit mal status	NTRK2 NTRK3 IL1RN	1.07e-03	67	88	3	C0270823
Disease	Complex Partial Status Epilepticus	NTRK2 NTRK3 IL1RN	1.07e-03	67	88	3	C0393734
Disease	Status Epilepticus	NTRK2 NTRK3 IL1RN	1.12e-03	68	88	3	C0038220
Disease	Autistic Disorder	KDM5B KDM5C NTRK2 GRIN2B IL1RN	1.12e-03	261	88	5	C0004352
Disease	autism spectrum disorder (implicated_via_orthology)	KDM5B KDM5A KDM5C KDM5D	1.13e-03	152	88	4	DOID:0060041 (implicated_via_orthology)
Disease	Parkinson's disease (implicated_via_orthology)	GAK HIPK2 ATP13A5 PTCH1	1.27e-03	157	88	4	DOID:14330 (implicated_via_orthology)
Disease	stomach cancer (is_implicated_in)	NTRK3 PTCH1 IL1RN	1.32e-03	72	88	3	DOID:10534 (is_implicated_in)
Disease	Retinitis pigmentosa	PRPF8 USH2A SLC7A14	1.43e-03	74	88	3	cv:C0035334
Disease	nicotine dependence symptom count, depressive symptom measurement	AOC1 GRIA4 GRIN2B	1.48e-03	75	88	3	EFO_0007006, EFO_0009262
Disease	aspartate aminotransferase measurement	CROT MYO7A NTRK2 PLEKHA3 DVL2 RNF213 PTCH1 IL1RN PHIP	1.50e-03	904	88	9	EFO_0004736
Disease	reading and spelling ability	PHYH MECOM PRKCH PHIP	1.56e-03	166	88	4	EFO_0005301
Disease	colorectal adenoma (is_marker_for)	PTCH1 SMAD4	1.61e-03	20	88	2	DOID:0050860 (is_marker_for)
Disease	epilepsy (biomarker_via_orthology)	GAPDH GRIN2B	1.78e-03	21	88	2	DOID:1826 (biomarker_via_orthology)
Disease	renal system measurement, blood urea nitrogen measurement	KBTBD8 MECOM	1.95e-03	22	88	2	EFO_0004741, EFO_0004742
Disease	cervical squamous cell carcinoma (is_marker_for)	ADAR FOXP3	1.95e-03	22	88	2	DOID:3744 (is_marker_for)
Disease	thalamus volume	SEMA3F FAT3 GNA12	2.12e-03	85	88	3	EFO_0006935
Disease	Carcinoma of lung	NTRK2 NTRK3	2.14e-03	23	88	2	C0684249
Disease	Intellectual Disability	CACNA1B KDM5A KDM5C MED12L GRIN2B PHIP	2.23e-03	447	88	6	C3714756
Disease	West Syndrome	NTRK2 GRIN2B	2.33e-03	24	88	2	C0037769
Disease	chronic myeloid leukemia (is_marker_for)	IL1RN SMAD4	2.94e-03	27	88	2	DOID:8552 (is_marker_for)
Disease	retinitis pigmentosa (implicated_via_orthology)	PRPF8 USH2A	2.94e-03	27	88	2	DOID:10584 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
VVMDFLMDHPDYPFS	AKR1C4	306	P17516
ENHFHVYMKGAPEMV	ATP13A5	616	Q4VNC0
YKGDVAMSKIEHFMP	AP1M2	21	Q9Y6Q5
FNVPMLYFMGDKDGQ	AKAP4	786	Q5JQC9
MFFEHLGVPAFYMSI	ACTRT3	121	Q9BYD9
AFTEMMEAYVPGFAH	CUEDC2	56	Q9H467
DFIFYPNGVMEAKMH	AOC1	466	P19801
MFAIIGLEFYMGKFH	CACNA1B	236	Q00975
MGEMEDKCYPYRNHI	CEMIP	501	Q8WUJ3
FHMAMGNPSEFFVDV	DVL2	721	O14641
RAPFGEKEAYMGFMN	RASAL3	651	Q86YV0
MVNMSHANPGLADYF	MECOM	456	Q03112
GEMKVYVIEPHSMEF	NUP210	526	Q8TEM1
DQKLFPYGEHLEMAM	FAM86B2	311	P0C5J1
VMSLPEEHNKMVYFA	LBP	266	P18428
MAPVYEGMASHVQVF	HIPK2	1	Q9H2X6
EYNEKLAFHMFQEGM	MED12L	231	Q86YW9
VFNTMGLYDGIEHFM	MAGEB10	226	Q96LZ2
HNMDYFKFHNMRPPF	FOXP3	326	Q9BZS1
DPLIMVFEYMKHGDL	NTRK3	611	Q16288
ADSFKSDYFNMPVHM	KDM5D	391	Q9BY66
PYVMYKKNHEMFEGN	GRIA4	426	P48058
PAFERMMGYHKGELL	PDE8B	296	O95263
FMMEYPSGLQTLHEF	GUCA1C	26	O95843
FHCMFEEMTKPEYGM	HERC6	721	Q8IVU3
NYPAFMMEMKHVFED	PEG10	146	Q86TG7
DREMFGYMKLHPEDF	NDUFC2	86	O95298
AFLVGPQFSMNHYMK	LPCAT3	196	Q6P1A2
ADAFKSDYFNMPVHM	KDM5B	386	Q9UGL1
FETGFYHSELNPMNM	MIER3	456	Q7Z3K6
DNFKSDYFNMPVHMV	KDM5A	371	P29375
AMPVAMEFHNAVEYK	KBTBD8	426	Q8NFY9
ENGMAPFFEMKLKHY	PALLD	996	Q8WX93
HLMGLFEPGDMKYEI	ALPP	286	P05187
VFITDDFHDMMPKYL	HSP90B1	416	P14625
DFHDMMPKYLNFVKG	HSP90B1	421	P14625
KMEDYGLPFMCHAGV	IL1RL2	306	Q9HB29
FCEAMDKYFLMVPDH	PIKFYVE	2076	Q9Y2I7
GQPYEQHAKMIFMEL	GAK	1281	O14976
MFEKYPGKMEGLFRH	FBRS	1	Q9HAH7
GEFRAIMEMPSFYSH	ADAR	471	P55265
MLFAVEMHSSEFYKP	FAT3	3701	Q8TDW7
PMTFEAVKQDHGFML	GLB1L	401	Q6UWU2
YSENEKHGMFLMAFE	GNA12	121	Q03113
FDYDTFGGHIMIMKN	CEMIP2	511	Q9UHN6
FEYETPEMEKKIMFH	IFI16	216	Q16666
GMHYFSPVDKMQLLE	HADHA	496	P40939
MPDEGVMVTKFYFQE	IL1RN	161	P18510
MGHAETYAEYMPIKL	SBNO1	236	A3KN83
FAMNHYGQPDVAMFD	MICAL2	356	O94851
DHAPFDAMIMVNISY	CROT	326	Q9UKG9
YIIEGFENMPAAFMG	PTGR1	301	Q14914
KYVECFTGPNIMAMH	PHYH	141	O14832
RQYEKMEFGVFPMEA	AK9	476	Q5TCS8
ELHPYMFHGGMNFEI	USH2A	1726	O75445
FHGAIMSVFPVVMYF	RGSL1	961	A5PLK6
FPAMIVFVDPKNFHM	PPP4R4	381	Q6NUP7
MADIRMVFNGPFAHK	SEMA3F	376	Q13275
ADAPMFVMGVNHEKY	GAPDH	126	P04406
MMVKDEYVHDFEGQP	SMAD4	156	Q13485
NHFIGEGMTKYDYLM	TENT5D	286	Q8NEK8
LMTPKQMYEHFKGYE	PTCH1	366	Q13635
LNKPFMDYGDTVMHG	SLC36A2	116	Q495M3
EEAPLHVMVFTYMGY	SPTLC3	56	Q9NUV7
YMPGKVAAFARHMLE	SPTLC3	466	Q9NUV7
YMFMHVGLEQLGFNA	RHBDL1	251	O75783
PHMLVVYSANGEMFK	OSBPL10	136	Q9BXB5
MAYSEEHKGMPCGFI	TRAF5	1	O00463
MLFEAFNTPAMHIAY	ACTL7A	186	Q9Y615
YHLPQEFGDAELMQM	CELF4	426	Q9BZC1
DPLIMVFEYMKHGDL	NTRK2	611	Q16620
YNFMGVRHDPNMKYE	PRPF8	2281	Q6P2Q9
PLMEMFVAHGFYAAK	SLC7A14	321	Q8TBB6
MFGFHKPKMYRSIEG	SINHCAF	1	Q9NP50
VMYMENFIEHLGRFP	RNF213	771	Q63HN8
MKMIHGDYIEKPDFA	SUN5	186	Q8TC36
GSFTMKYHDMPDVID	PHIP	1036	Q8WWQ0
LFHAAKAYEQAGMML	NAPG	71	Q99747
YFPKMVEMHNYVPAN	SPEF1	46	Q9Y4P9
HGPLDMSNKMFSAEY	TTC3	1121	P53804
EHMVFMGSLKYPDEN	NRDC	236	O43847
EMFYVLFSMAKLPHE	RASD2	181	Q96D21
YHPDKGGDEVMFMRI	SEC63	131	Q9UGP8
DREMFGYMKLHPEDF	NDUFC2-KCTD14	86	E9PQ53
MELIIPGEQHFYMKA	PLEKHA3	61	Q9HB20
MEHPSKMEFFQKLGY	ZC3H12D	1	A2A288
QDFFTMIGMEHPKLF	XXYLT1	331	Q8NBI6
ADSFKADYFNMPVHM	KDM5C	401	P41229
FVMEFVNGGDLMFHI	PRKCH	431	P24723
PVNHSDMVDKMFGFL	MYO7A	936	Q13402
DKGRFMDGSPYAHMF	GRIN2B	1326	Q13224