Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF805 ZNF12 ZNF311 ZNF615 ZNF841 TAF1 ZNF605 ZNF543 ZBED4 ZFP2 MAZ ZNF589	1.80e-05	1459	40	12	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF805 ZNF12 ZNF311 ZNF615 ZNF841 ZNF605 ZNF543 ZBED4 ZFP2 MAZ ZNF589	7.26e-05	1412	40	11	GO:0000981
GeneOntologyMolecularFunction	frizzled binding	WNT10A WNT8A WNT8B	8.10e-05	42	40	3	GO:0005109
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF805 ZNF12 ZNF311 ZNF615 ZNF841 ZNF605 ZNF543 ZFP2 MAZ	6.47e-04	1244	40	9	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF805 ZNF12 ZNF311 ZNF615 ZNF841 ZNF605 ZNF543 ZFP2 MAZ	7.56e-04	1271	40	9	GO:0000987
GeneOntologyBiologicalProcess	canonical Wnt signaling pathway	WNT10A USP34 AMER3 EGF WNT8A WNT8B	4.90e-05	344	40	6	GO:0060070
GeneOntologyBiologicalProcess	Wnt signaling pathway	LRP1 WNT10A USP34 AMER3 EGF WNT8A WNT8B	5.36e-05	516	40	7	GO:0016055
GeneOntologyBiologicalProcess	positive regulation of Schwann cell migration	LRP1 PTPRZ1	1.02e-04	8	40	2	GO:1900149
GeneOntologyCellularComponent	synapse-associated extracellular matrix	SPARCL1 PTPRZ1	2.61e-04	13	39	2	GO:0099535
Domain	zf-C2H2_6	ZNF805 ZNF12 ZNF311 ZNF615 ZNF841 ZNF605 ZNF543 ZFP2	1.84e-07	314	38	8	PF13912
Domain	-	ZNF805 ZNF12 ZNF311 ZNF615 ZNF841 ZNF605 ZNF543 ZFP2 MAZ ZNF589	7.09e-07	679	38	10	3.30.160.60
Domain	zf-C2H2	ZNF805 ZNF12 ZNF311 ZNF615 ZNF841 ZNF605 ZNF543 ZFP2 MAZ ZNF589	8.54e-07	693	38	10	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF805 ZNF12 ZNF311 ZNF615 ZNF841 ZNF605 ZNF543 ZFP2 MAZ ZNF589	8.66e-07	694	38	10	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF805 ZNF12 ZNF311 ZNF615 ZNF841 ZNF605 ZNF543 ZFP2 MAZ ZNF589	2.35e-06	775	38	10	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF805 ZNF12 ZNF311 ZNF615 ZNF841 ZNF605 ZNF543 ZFP2 MAZ ZNF589	2.40e-06	777	38	10	PS00028
Domain	Znf_C2H2-like	ZNF805 ZNF12 ZNF311 ZNF615 ZNF841 ZNF605 ZNF543 ZFP2 MAZ ZNF589	2.98e-06	796	38	10	IPR015880
Domain	Znf_C2H2	ZNF805 ZNF12 ZNF311 ZNF615 ZNF841 ZNF605 ZNF543 ZFP2 MAZ ZNF589	3.30e-06	805	38	10	IPR007087
Domain	ZnF_C2H2	ZNF805 ZNF12 ZNF311 ZNF615 ZNF841 ZNF605 ZNF543 ZFP2 MAZ ZNF589	3.41e-06	808	38	10	SM00355
Domain	Wnt8	WNT8A WNT8B	4.03e-06	2	38	2	IPR013301
Domain	KRAB	ZNF805 ZNF12 ZNF311 ZNF615 ZNF605 ZNF543 ZNF589	6.78e-06	358	38	7	PS50805
Domain	KRAB	ZNF805 ZNF12 ZNF311 ZNF615 ZNF605 ZNF543 ZNF589	6.78e-06	358	38	7	PF01352
Domain	Wnt	WNT10A WNT8A WNT8B	7.36e-06	19	38	3	IPR005817
Domain	WNT1	WNT10A WNT8A WNT8B	7.36e-06	19	38	3	SM00097
Domain	Wnt_CS	WNT10A WNT8A WNT8B	7.36e-06	19	38	3	IPR018161
Domain	wnt	WNT10A WNT8A WNT8B	7.36e-06	19	38	3	PF00110
Domain	WNT1	WNT10A WNT8A WNT8B	7.36e-06	19	38	3	PS00246
Domain	KRAB	ZNF805 ZNF12 ZNF311 ZNF615 ZNF605 ZNF543 ZNF589	8.26e-06	369	38	7	SM00349
Domain	KRAB	ZNF805 ZNF12 ZNF311 ZNF615 ZNF605 ZNF543 ZNF589	8.41e-06	370	38	7	IPR001909
Domain	Ldl_recept_b	LRP1 EGF	3.61e-04	14	38	2	PF00058
Domain	LDLRB	LRP1 EGF	3.61e-04	14	38	2	PS51120
Domain	LY	LRP1 EGF	4.16e-04	15	38	2	SM00135
Domain	LDLR_classB_rpt	LRP1 EGF	4.16e-04	15	38	2	IPR000033
Domain	ZF_CCHC	SLU7 ZCCHC3	2.30e-03	35	38	2	PS50158
Domain	-	LRP1 EGF	2.85e-03	39	38	2	2.120.10.30
Domain	6-blade_b-propeller_TolB-like	LRP1 EGF	3.94e-03	46	38	2	IPR011042
Domain	ZnF_C2HC	SLU7 ZCCHC3	5.59e-03	55	38	2	SM00343
Domain	Znf_CCHC	SLU7 ZCCHC3	5.59e-03	55	38	2	IPR001878
Domain	-	MALT1 ASTN1 HLA-C PTPRZ1 MYPN	1.06e-02	663	38	5	2.60.40.10
Domain	EGF_3	LRP1 ASTN1 EGF	1.20e-02	235	38	3	PS50026
Domain	EGF	LRP1 ASTN1 EGF	1.20e-02	235	38	3	SM00181
Domain	EGF_CA	LRP1 EGF	1.32e-02	86	38	2	PF07645
Domain	Ig-like_fold	MALT1 ASTN1 HLA-C PTPRZ1 MYPN	1.36e-02	706	38	5	IPR013783
Domain	EGF-like_dom	LRP1 ASTN1 EGF	1.40e-02	249	38	3	IPR000742
Domain	EGF_1	LRP1 ASTN1 EGF	1.49e-02	255	38	3	PS00022
Domain	EGF-like_CS	LRP1 ASTN1 EGF	1.59e-02	261	38	3	IPR013032
Domain	EGF_2	LRP1 ASTN1 EGF	1.65e-02	265	38	3	PS01186
Domain	EGF_Ca-bd_CS	LRP1 EGF	1.66e-02	97	38	2	IPR018097
Domain	EGF_CA	LRP1 EGF	1.73e-02	99	38	2	PS01187
Domain	ASX_HYDROXYL	LRP1 EGF	1.76e-02	100	38	2	PS00010
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_ACYLATION	WNT10A WNT8A WNT8B	6.66e-06	19	28	3	M47836
Pathway	REACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING	WNT10A WNT8A WNT8B	1.57e-05	25	28	3	MM14940
Pathway	REACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING	WNT10A WNT8A WNT8B	1.77e-05	26	28	3	M27239
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR	WNT10A WNT8A WNT8B	2.22e-05	28	28	3	M47835
Pathway	WP_POLYCYSTIC_KIDNEY_DISEASE_PATHWAY	WNT10A EGF WNT8A WNT8B	2.26e-05	85	28	4	M48315
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY	WNT10A WNT8A WNT8B	2.48e-05	29	28	3	M47372
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY	WNT10A WNT8A WNT8B	2.48e-05	29	28	3	M47377
Pathway	KEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY	WNT10A WNT8A WNT8B	5.21e-05	37	28	3	M47411
Pathway	BIOCARTA_WNT_LRP6_PATHWAY	WNT8A WNT8B	5.68e-05	6	28	2	MM1588
Pathway	BIOCARTA_WNT_LRP6_PATHWAY	WNT8A WNT8B	5.68e-05	6	28	2	M22083
Pathway	KEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY	WNT10A WNT8A WNT8B	9.42e-05	45	28	3	M47412
Pathway	KEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY	WNT10A WNT8A WNT8B	1.01e-04	46	28	3	M47409
Pathway	KEGG_BASAL_CELL_CARCINOMA	WNT10A WNT8A WNT8B	1.72e-04	55	28	3	M17807
Pathway	KEGG_HEDGEHOG_SIGNALING_PATHWAY	WNT10A WNT8A WNT8B	1.81e-04	56	28	3	M1053
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF12 SLU7 ZNF311 ZNF615 TAF1 ZNF605 ZNF543 TAF10 ZFP2 ZNF589	2.05e-04	1387	28	10	M734
Pathway	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	WNT10A WNT8A WNT8B	8.34e-04	94	28	3	M797
Pathway	KEGG_MELANOGENESIS	WNT10A WNT8A WNT8B	1.03e-03	101	28	3	M7761
Pathway	REACTOME_SIGNALING_BY_WNT	WNT10A USP34 WNT8A WNT8B	1.20e-03	239	28	4	MM14756
Pathway	WP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES	WNT10A WNT8A WNT8B	1.61e-03	118	28	3	M39852
Pathway	REACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE	WNT8A WNT8B	1.71e-03	31	28	2	M27400
Pathway	REACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE	WNT8A WNT8B	1.71e-03	31	28	2	MM15154
Pathway	KEGG_BASAL_TRANSCRIPTION_FACTORS	TAF1 TAF10	2.17e-03	35	28	2	M4864
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF805 ZNF311 ZNF615 ZNF841 ZNF543 ZNF589	6.06e-08	181	40	6	37372979
Pubmed	Expression patterns of Wnt genes in mouse gut development.	WNT10A WNT8A WNT8B	6.35e-07	15	40	3	11429295
Pubmed	Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.	WNT10A WNT8A WNT8B	9.48e-07	17	40	3	28733458
Pubmed	Expression and regulation of WNT8A and WNT8B mRNAs in human tumor cell lines: up-regulation of WNT8B mRNA by beta-estradiol in MCF-7 cells, and down-regulation of WNT8A and WNT8B mRNAs by retinoic acid in NT2 cells.	WNT8A WNT8B	1.29e-06	2	40	2	11956596
Pubmed	Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis.	WNT10A WNT8A WNT8B	1.35e-06	19	40	3	11520664
Pubmed	Coronary Artery Formation Is Driven by Localized Expression of R-spondin3.	WNT10A WNT8A WNT8B	1.35e-06	19	40	3	28834739
Pubmed	The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium.	WNT10A WNT8A WNT8B	1.85e-06	21	40	3	11914369
Pubmed	Does murine spermatogenesis require WNT signalling? A lesson from Gpr177 conditional knockout mouse models.	WNT10A WNT8A WNT8B	2.46e-06	23	40	3	27362799
Pubmed	Protein phosphorylation and expression profiling by Yin-yang multidimensional liquid chromatography (Yin-yang MDLC) mass spectrometry.	USP34 GVINP1	3.87e-06	3	40	2	17203969
Pubmed	Activation of the Wnt-beta catenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections.	WNT10A WNT8A WNT8B	4.04e-06	27	40	3	17804636
Pubmed	Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes.	WNT10A WNT8A WNT8B	4.53e-06	28	40	3	20940229
Pubmed	Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development.	WNT10A WNT8A WNT8B	4.53e-06	28	40	3	24394376
Pubmed	Wnt5a potentiates TGF-β signaling to promote colonic crypt regeneration after tissue injury.	WNT10A WNT8A WNT8B	5.04e-06	29	40	3	22956684
Pubmed	3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19).	WNT10A WNT8A WNT8B	5.04e-06	29	40	3	18364260
Pubmed	Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tract.	WNT10A WNT8A WNT8B	5.60e-06	30	40	3	21936019
Pubmed	Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development.	WNT10A WNT8A WNT8B	5.60e-06	30	40	3	15880404
Pubmed	Genetic interactions of the androgen and Wnt/beta-catenin pathways for the masculinization of external genitalia.	WNT10A WNT8A WNT8B	5.60e-06	30	40	3	19282366
Pubmed	Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development.	WNT10A WNT8A WNT8B	5.60e-06	30	40	3	36305473
Pubmed	Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor.	TAF1 TAF10	7.73e-06	4	40	2	7923369
Pubmed	WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis.	WNT10A WNT8A WNT8B	8.99e-06	35	40	3	30940800
Pubmed	Foxf2 in intestinal fibroblasts reduces numbers of Lgr5(+) stem cells and adenoma formation by inhibiting Wnt signaling.	WNT10A WNT8A WNT8B	8.99e-06	35	40	3	23376422
Pubmed	Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation.	WNT10A WNT8A WNT8B	8.99e-06	35	40	3	19185060
Pubmed	Integrated analysis of Wnt signalling system component gene expression.	WNT10A WNT8A WNT8B	1.07e-05	37	40	3	35831952
Pubmed	Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis.	WNT10A WNT8A WNT8B	1.07e-05	37	40	3	15342465
Pubmed	Tissue-specific requirements of beta-catenin in external genitalia development.	WNT10A WNT8A WNT8B	1.16e-05	38	40	3	18635608
Pubmed	Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis.	WNT10A WNT8A WNT8B	1.16e-05	38	40	3	23190887
Pubmed	Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals.	WNT10A WNT8A WNT8B	1.16e-05	38	40	3	21041481
Pubmed	Distinct requirements for cranial ectoderm and mesenchyme-derived wnts in specification and differentiation of osteoblast and dermal progenitors.	WNT10A WNT8A WNT8B	1.25e-05	39	40	3	24586192
Pubmed	Gpr177 regulates pulmonary vasculature development.	WNT10A WNT8A WNT8B	1.81e-05	44	40	3	23884445
Pubmed	Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation.	TAF1 TAF10	1.93e-05	6	40	2	7680771
Pubmed	Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene.	ASTN1 SPARCL1	1.93e-05	6	40	2	18384059
Pubmed	Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination.	WNT10A WNT8A WNT8B	2.21e-05	47	40	3	16678101
Pubmed	Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.	WNT10A WNT8A WNT8B	2.21e-05	47	40	3	28813421
Pubmed	Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.	WNT10A WNT8A WNT8B	2.21e-05	47	40	3	33141892
Pubmed	Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.	WNT10A WNT8A WNT8B	2.50e-05	49	40	3	19562671
Pubmed	Several regions in the major histocompatibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus.	ZNF311 HLA-C	2.70e-05	7	40	2	18309376
Pubmed	Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID.	TAF1 TAF10	2.70e-05	7	40	2	7729427
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	LRP1 USP34 MALT1 TAF1 TAF10 ZMYM3 MAZ ZNF589	3.38e-05	1116	40	8	31753913
Pubmed	Common variants in the trichohyalin gene are associated with straight hair in Europeans.	WNT10A EGF	3.60e-05	8	40	2	19896111
Pubmed	Spatial and temporal expression of Wnt and Dickkopf genes during murine lens development.	WNT8A WNT8B	4.62e-05	9	40	2	15053977
Pubmed	The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation.	TAF1 TAF10	4.62e-05	9	40	2	12665565
Pubmed	HIV-1 tat binds TAFII250 and represses TAFII250-dependent transcription of major histocompatibility class I genes.	TAF1 HLA-C	4.62e-05	9	40	2	9751712
Pubmed	Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea.	WNT8A WNT8B	4.62e-05	9	40	2	12702652
Pubmed	CCAAT binding NF-Y-TBP interactions: NF-YB and NF-YC require short domains adjacent to their histone fold motifs for association with TBP basic residues.	TAF1 TAF10	7.05e-05	11	40	2	9153318
Pubmed	Epicardial retinoid X receptor alpha is required for myocardial growth and coronary artery formation.	WNT8A WNT8B	8.45e-05	12	40	2	16352730
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	LRP1 USP34 TAF1 ZMYM3 LIN54	1.14e-04	418	40	5	34709266
Pubmed	Identification of a small TAF complex and its role in the assembly of TAF-containing complexes.	TAF1 TAF10	1.16e-04	14	40	2	17375202
Pubmed	Structure of promoter-bound TFIID and model of human pre-initiation complex assembly.	TAF1 TAF10	1.16e-04	14	40	2	27007846
Pubmed	Human TFIID binds to core promoter DNA in a reorganized structural state.	TAF1 TAF10	1.16e-04	14	40	2	23332750
Pubmed	SAGE reveals expression of Wnt signalling pathway members during mouse prostate development.	WNT8A WNT8B	1.16e-04	14	40	2	16378759
Pubmed	Expression and estradiol regulation of Wnt genes in the mouse blastocyst identify a candidate pathway for embryo-maternal signaling at implantation.	WNT10A WNT8B	1.34e-04	15	40	2	15044261
Pubmed	The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis.	TAF1 TAF10	1.34e-04	15	40	2	14580349
Pubmed	Wild-type and transactivation-defective mutants of human immunodeficiency virus type 1 Tat protein bind human TATA-binding protein in vitro.	TAF1 TAF10	1.53e-04	16	40	2	8680883
Pubmed	Molecular genetic studies of Wnt signaling in the mouse.	WNT10A WNT8B	1.53e-04	16	40	2	10585256
Pubmed	Mutations in the carboxy-terminal domain of TBP affect the synthesis of human immunodeficiency virus type 1 full-length and short transcripts similarly.	TAF1 TAF10	1.53e-04	16	40	2	8764009
Pubmed	Direct interaction of human TFIID with the HIV-1 transactivator tat.	TAF1 TAF10	1.53e-04	16	40	2	8121496
Pubmed	A novel LBP-1-mediated restriction of HIV-1 transcription at the level of elongation in vitro.	TAF1 TAF10	1.53e-04	16	40	2	7836461
Pubmed	The Wnts.	WNT10A WNT8B	1.53e-04	16	40	2	9889131
Pubmed	Novel mechanism and factor for regulation by HIV-1 Tat.	TAF1 TAF10	1.53e-04	16	40	2	7835343
Pubmed	Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.	WNT10A WNT8A WNT8B	1.54e-04	90	40	3	19515997
Pubmed	Wnt family proteins are secreted and associated with the cell surface.	WNT8A WNT8B	1.73e-04	17	40	2	8167409
Pubmed	Histone-like TAFs within the PCAF histone acetylase complex.	TAF1 TAF10	1.73e-04	17	40	2	9674425
Pubmed	Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.	TAF1 TAF10	1.95e-04	18	40	2	29111974
Pubmed	Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression.	TAF1 TAF10	1.95e-04	18	40	2	15053879
Pubmed	Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function.	TAF1 TAF10	1.95e-04	18	40	2	7933101
Pubmed	Interaction of human immunodeficiency virus type 1 Tat with a unique site of TFIID inhibits negative cofactor Dr1 and stabilizes the TFIID-TFIIA complex.	TAF1 TAF10	2.18e-04	19	40	2	8764062
Pubmed	Function of TAF(II)-containing complex without TBP in transcription by RNA polymerase II.	TAF1 TAF10	2.42e-04	20	40	2	9603525
Pubmed	Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4.	TAF1 TAF10	2.42e-04	20	40	2	17884155
Pubmed	STAGA recruits Mediator to the MYC oncoprotein to stimulate transcription and cell proliferation.	TAF1 TAF10	2.42e-04	20	40	2	17967894
Pubmed	Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis.	WNT10A WNT8A	2.67e-04	21	40	2	17943183
Pubmed	Epithelial Wnt10a Is Essential for Tooth Root Furcation Morphogenesis.	WNT10A WNT8B	2.67e-04	21	40	2	31914354
Pubmed	Characterization of Wnt signaling components and activation of the Wnt canonical pathway in the murine retina.	WNT10A WNT8B	2.94e-04	22	40	2	12815618
Pubmed	Motor neurons with axial muscle projections specified by Wnt4/5 signaling.	WNT8A WNT8B	2.94e-04	22	40	2	19285468
Pubmed	Activation of beta-Catenin in mouse prostate causes HGPIN and continuous prostate growth after castration.	WNT10A WNT8B	2.94e-04	22	40	2	18991257
Pubmed	Selective recognition of viral promoters by host cell transcription complexes: challenges and opportunities to control latency.	TAF1 TAF10	3.50e-04	24	40	2	23827503
Pubmed	The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function.	TAF1 TAF10	3.80e-04	25	40	2	19240132
Pubmed	A role for Wnt/beta-catenin signaling in lens epithelial differentiation.	WNT8A WNT8B	3.80e-04	25	40	2	12812787
Pubmed	KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors.	WNT10A WNT8B	5.87e-04	31	40	2	37838801
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	LRP1 USP34 ASTN1 SPARCL1 ZNF841 TAF1 ZNF605	5.92e-04	1285	40	7	35914814
Pubmed	NOTCH maintains developmental cardiac gene network through WNT5A.	WNT10A WNT8A	6.26e-04	32	40	2	30347193
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ZNF12 TAF1 ZMYM3 MAZ LIN54	6.37e-04	608	40	5	36089195
Pubmed	Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.	TAF1 TAF10	6.66e-04	33	40	2	11564863
Pubmed	Association of Tat with purified HIV-1 and HIV-2 transcription preinitiation complexes.	TAF1 TAF10	9.30e-04	39	40	2	9054383
Pubmed	The general transcription factors of RNA polymerase II.	TAF1 TAF10	9.30e-04	39	40	2	8946909
Pubmed	Three transitions in the RNA polymerase II transcription complex during initiation.	TAF1 TAF10	9.30e-04	39	40	2	9405375
Pubmed	Abortive initiation is increased only for the weakest members of a set of down mutants of the adenovirus 2 major late promoter.	TAF1 TAF10	9.79e-04	40	40	2	1939271
Pubmed	ATP activates transcription initiation from promoters by RNA polymerase II in a reversible step prior to RNA synthesis.	TAF1 TAF10	9.79e-04	40	40	2	2449431
Pubmed	USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.	RGS8 SPARCL1 TAF1 EGF MYPN	1.01e-03	674	40	5	37196079
Pubmed	Human transcription factor protein interaction networks.	SLU7 TAF1 TAF10 ZMYM3 ZCCHC3 MAZ LIN54	1.10e-03	1429	40	7	35140242
Pubmed	Dominant and redundant functions of TFIID involved in the regulation of hepatic genes.	TAF1 TAF10	1.13e-03	43	40	2	18722179
Cytoband	Xq13.1	TAF1 ZMYM3	8.14e-04	48	40	2	Xq13.1
Cytoband	19q13.41	ZNF615 ZNF841	2.13e-03	78	40	2	19q13.41
Cytoband	19q13.43	ZNF805 ZNF543	2.64e-03	87	40	2	19q13.43
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF805 ZNF615 ZNF841 PINLYP ZNF543	3.62e-03	1192	40	5	chr19q13
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF805 ZNF12 ZNF311 ZNF615 ZNF841 ZNF605 ZNF543 ZFP2 MAZ ZNF589	3.70e-07	718	33	10	28
GeneFamily	Wnt family\|Endogenous ligands	WNT10A WNT8A WNT8B	5.26e-06	19	33	3	360
Disease	hair morphology	WNT10A EGF	6.08e-04	29	37	2	EFO_0005038
Disease	Paroxysmal atrial fibrillation	USP34 WNT8A MYPN	9.87e-04	156	37	3	C0235480
Disease	Persistent atrial fibrillation	USP34 WNT8A MYPN	9.87e-04	156	37	3	C2585653
Disease	familial atrial fibrillation	USP34 WNT8A MYPN	9.87e-04	156	37	3	C3468561
Disease	Atrial Fibrillation	USP34 WNT8A MYPN	1.06e-03	160	37	3	C0004238
Disease	thioredoxin domain-containing protein 12 measurement	KLHL18 ZNF589	1.10e-03	39	37	2	EFO_0008298
Disease	cardiomyopathy (implicated_via_orthology)	LRP1 SPARCL1	3.60e-03	71	37	2	DOID:0050700 (implicated_via_orthology)
Disease	susceptibility to Mycobacterium tuberculosis infection measurement	ZNF311 HLA-C	5.23e-03	86	37	2	EFO_0008407
Disease	Adenocarcinoma of large intestine	DCLK3 TAF1	6.48e-03	96	37	2	C1319315

Protein segments in the cluster

Peptide	Gene	Start	Entry
KCKTHDSMSGAGRAT	AMER3	91	Q8N944
HRHCTGSRKDCLLMG	GVINP1	1081	Q7Z2Y8
GVRMECHSKGRCPSS	ASTN1	936	O14525
SDRRHSKGCNCKRSG	LIN54	591	Q6MZP7
DMHRGLGRKTCFQTC	MALT1	716	Q9UDY8
TKGGHLCSCARNFMK	LRP1	3841	Q07954
KSCSEVAGCKAAMRH	DCLK3	61	Q9C098
MMCRRKSSGGKGGSC	HLA-C	331	P10321
ICTAAGSRCHGQMKT	PINLYP	31	A6NC86
GSRCHGQMKTCSSDK	PINLYP	36	A6NC86
SGKRIRKNHACEMCG	MAZ	271	P56270
RKNHACEMCGKAFRD	MAZ	276	P56270
DRGSDGLSIHKCMSC	PTPRZ1	1431	P23471
KRCRHGAASLGSKMF	KLHL18	466	O94889
SCREGFMKASDGKTC	EGF	766	P01133
CHCKSGTMSRSRSGK	MENT	211	Q9BUN1
KGMRTRLGCLSHKSD	RGS8	11	P57771
LQHCKMKGTASGSSR	TAF10	171	Q12962
KLKCGACGAIGHMRT	TAF1	1261	P21675
RLKCKNCGAFGHMAR	FAM90A26	41	D6RGX4
GTCCFQMLHKSKGRT	CHODL	236	Q9H9P2
PHVCSMCGKAFSRKS	ZNF615	231	Q8N8J6
AVKGTMKRTCKCHGV	WNT8B	171	Q93098
MKRTCKCHGVSGSCT	WNT8B	176	Q93098
QPKTCFKCGSRTHMS	ZCCHC3	331	Q9NUD5
FKCGSRTHMSGSCTQ	ZCCHC3	336	Q9NUD5
DSCMSFQCKRGHICK	SPARCL1	431	Q14515
TNAKHGLRCKACKMS	STAC	131	Q99469
RKGACENCGAMTHKK	SLU7	116	O95391
MSHGNKETFSCRGIK	ZC3H12D	101	A2A288
MECGKAFGRRSCLTK	ZNF841	736	Q6ZN19
KCMECGKAFNRRSHL	ZNF543	256	Q08ER8
KCMECGKAFNRRSHL	ZNF543	396	Q08ER8
ARMKADECSGCGKSL	ZNF12	161	P17014
CMVCGKHFTGRSSLT	ZFP2	356	Q6ZN57
GDNMYTCSHCGKKVR	USP34	2056	Q70CQ2
MKRTCKCHGISGSCS	WNT8A	176	Q9H1J5
ENMRRKCKCHGTSGS	WNT10A	256	Q9GZT5
HTREKSFMCTVCGRG	ZNF589	326	Q86UQ0
CLSAKNMSHVKGGCI	SLC5A1	301	P13866
CGECGKSFTRKSHLM	ZNF605	591	Q86T29
CMECGKAFNRKSHLT	ZNF805	261	Q5CZA5
GRSAVGTKMTCAHCR	ZMYM3	301	Q14202
CGKAFKTRNRLCMHQ	ZNF311	336	Q5JNZ3
CIHCMNEFSRGKNGK	ZBED4	306	O75132
HCKMRREGDGTCSLH	MYPN	991	Q86TC9