Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	diacylglycerol-dependent serine/threonine kinase activity	PRKCD PRKCE PRKCI	3.60e-05	16	82	3	GO:0004697
GeneOntologyMolecularFunction	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	PRKCD PRKCE	4.98e-05	3	82	2	GO:0004699
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF20A DNAH10 MYO5A MYO5B DNAH17	1.26e-04	118	82	5	GO:0003774
GeneOntologyMolecularFunction	outward rectifier potassium channel activity	KCNT2 KCNB1 KCND1	1.82e-04	27	82	3	GO:0015271
GeneOntologyMolecularFunction	ATP-dependent activity	KIF20A ACSL3 DNAH10 MYO5A MYO5B DNAH17 DHX57 MCM6 ATP4A MOV10	2.05e-04	614	82	10	GO:0140657
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	DCAF1 PRAMEF7 PRAMEF12 PRAMEF8	3.62e-04	82	82	4	GO:1990756
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	KCNT2 KCNB1 KCND1 TMEM38A ATP4A	6.26e-04	167	82	5	GO:0015079
GeneOntologyMolecularFunction	enzyme-substrate adaptor activity	DCAF1 PRAMEF7 PRAMEF12 PRAMEF8	6.33e-04	95	82	4	GO:0140767
GeneOntologyMolecularFunction	G-quadruplex RNA binding	XRN1 MCRS1	7.34e-04	10	82	2	GO:0002151
GeneOntologyMolecularFunction	nuclear receptor binding	DCAF1 PRAMEF7 PRAMEF12 PRAMEF8 PADI2	1.04e-03	187	82	5	GO:0016922
GeneOntologyBiologicalProcess	positive regulation of protein localization to plasma membrane	ACSL3 MYO5A MYO5B PRKCE PRKCI	8.17e-06	70	81	5	GO:1903078
GeneOntologyBiologicalProcess	positive regulation of protein localization to membrane	ACSL3 KCNB1 MYO5A MYO5B PRKCE PRKCI	1.23e-05	130	81	6	GO:1905477
GeneOntologyBiologicalProcess	positive regulation of protein localization to cell periphery	ACSL3 MYO5A MYO5B PRKCE PRKCI	1.77e-05	82	81	5	GO:1904377
GeneOntologyBiologicalProcess	regulation of DNA metabolic process	SUPT20H BRCA1 XRN1 PRKCD MCRS1 MCM6 CDT1 TTF1 PHF10 CCNA2	7.09e-05	564	81	10	GO:0051052
GeneOntologyBiologicalProcess	cellular response to insulin stimulus	GPLD1 MYO5A PSG5 GPT PRKCD PRKCI PCSK9	9.49e-05	271	81	7	GO:0032869
GeneOntologyBiologicalProcess	positive regulation of protein localization	ACSL3 GPLD1 BRCA1 KCNB1 MYO5A MYO5B PRKCD PRKCE MCRS1 PRKCI	1.04e-04	591	81	10	GO:1903829
GeneOntologyBiologicalProcess	cellular response to hormone stimulus	GPLD1 BRCA1 MYO5A PSG5 GPT PRKCD PRKCE PRKCI PADI2 PCSK9 CCNA2	1.24e-04	727	81	11	GO:0032870
GeneOntologyBiologicalProcess	cellular response to peptide hormone stimulus	GPLD1 MYO5A PSG5 GPT PRKCD PRKCI PCSK9 CCNA2	1.25e-04	381	81	8	GO:0071375
GeneOntologyBiologicalProcess	regulation of protein localization to plasma membrane	ACSL3 MYO5A MYO5B PRKCE PRKCI	1.49e-04	128	81	5	GO:1903076
GeneOntologyBiologicalProcess	cellular response to nitrogen compound	GPLD1 BRCA1 MYO5A PSG5 GPT TMEM38A XRN1 PRKCD PRKCI PCSK9 CCNA2	1.67e-04	752	81	11	GO:1901699
GeneOntologyBiologicalProcess	cellular response to platelet-derived growth factor stimulus	MARS1 PRKCE CCNA2	1.78e-04	28	81	3	GO:0036120
GeneOntologyBiologicalProcess	negative regulation of homotypic cell-cell adhesion	CCM2L PSG5 PRKCD	1.78e-04	28	81	3	GO:0034111
GeneOntologyBiologicalProcess	response to platelet-derived growth factor	MARS1 PRKCE CCNA2	2.42e-04	31	81	3	GO:0036119
GeneOntologyBiologicalProcess	protein localization to plasma membrane	ACSL3 PRAM1 KCNB1 MYO5A MYO5B PRKCE PRKCI	2.84e-04	324	81	7	GO:0072659
GeneOntologyBiologicalProcess	regulation of DNA replication	MCRS1 MCM6 CDT1 TTF1 CCNA2	2.85e-04	147	81	5	GO:0006275
GeneOntologyBiologicalProcess	regulation of protein localization to membrane	ACSL3 KCNB1 MYO5A MYO5B PRKCE PRKCI	3.42e-04	237	81	6	GO:1905475
GeneOntologyCellularComponent	extrinsic component of external side of plasma membrane	CUBN PCSK9	9.52e-05	4	84	2	GO:0031232
GeneOntologyCellularComponent	endolysosome	RNF167 PRKCD PCSK9	2.35e-04	30	84	3	GO:0036019
Domain	PRAME_family	PRAMEF7 PRAMEF12 PRAMEF8	7.24e-05	19	81	3	IPR026271
Domain	DAG/PE-bd	PRKCD PRKCE PRKCI	9.88e-05	21	81	3	IPR020454
Domain	Channel_four-helix_dom	KCNB1 KCND1 TPTE2 SCN4A	1.09e-04	57	81	4	IPR027359
Domain	-	KCNB1 KCND1 TPTE2 SCN4A	1.09e-04	57	81	4	1.20.120.350
Domain	Prot_kin_PKC_delta	PRKCD PRKCE	1.11e-04	4	81	2	IPR014376
Domain	Myosin_S1_N	MYO5A MYO5B	1.84e-04	5	81	2	IPR008989
Domain	DIL	MYO5A MYO5B	2.76e-04	6	81	2	PF01843
Domain	Dilute_dom	MYO5A MYO5B	2.76e-04	6	81	2	IPR002710
Domain	DILUTE	MYO5A MYO5B	2.76e-04	6	81	2	PS51126
Domain	DIL	MYO5A MYO5B	2.76e-04	6	81	2	SM01132
Domain	Calx_beta	FREM2 ADGRV1	5.11e-04	8	81	2	SM00237
Domain	Pkinase_C	PRKCD PRKCE PRKCI	5.49e-04	37	81	3	IPR017892
Domain	Calx_beta	FREM2 ADGRV1	6.56e-04	9	81	2	IPR003644
Domain	Calx-beta	FREM2 ADGRV1	6.56e-04	9	81	2	PF03160
Domain	Pkinase_C	PRKCD PRKCE PRKCI	7.99e-04	42	81	3	PF00433
Domain	Ion_trans_dom	KCNB1 KCND1 TPTE2 SCN4A	1.53e-03	114	81	4	IPR005821
Domain	Ion_trans	KCNB1 KCND1 TPTE2 SCN4A	1.53e-03	114	81	4	PF00520
Domain	AGC-kinase_C	PRKCD PRKCE PRKCI	1.85e-03	56	81	3	IPR000961
Domain	AGC_KINASE_CTER	PRKCD PRKCE PRKCI	1.85e-03	56	81	3	PS51285
Domain	S_TK_X	PRKCD PRKCE PRKCI	1.85e-03	56	81	3	SM00133
Domain	C1_1	PRKCD PRKCE PRKCI	1.94e-03	57	81	3	PF00130
Domain	ZF_DAG_PE_1	PRKCD PRKCE PRKCI	2.71e-03	64	81	3	PS00479
Domain	ZF_DAG_PE_2	PRKCD PRKCE PRKCI	2.71e-03	64	81	3	PS50081
Domain	C1	PRKCD PRKCE PRKCI	2.83e-03	65	81	3	SM00109
Domain	PE/DAG-bd	PRKCD PRKCE PRKCI	2.95e-03	66	81	3	IPR002219
Domain	P-loop_NTPase	KIF20A DNAH10 MYO5A MYO5B GBP3 DHX57 MCM6 GNAT1 MOV10 NLRP6	3.58e-03	848	81	10	IPR027417
Domain	IQ	MYO5A MYO5B SCN4A	3.63e-03	71	81	3	PF00612
Domain	IQ	MYO5A MYO5B SCN4A	5.26e-03	81	81	3	SM00015
Domain	GST_C	PTGES2 MARS1	5.64e-03	26	81	2	IPR004046
Domain	GST_C	PTGES2 MARS1	5.64e-03	26	81	2	PF00043
Domain	K_chnl_volt-dep_Kv	KCNB1 KCND1	6.08e-03	27	81	2	IPR003968
Domain	IQ_motif_EF-hand-BS	MYO5A MYO5B SCN4A	7.04e-03	90	81	3	IPR000048
Domain	IQ	MYO5A MYO5B SCN4A	7.71e-03	93	81	3	PS50096
Pubmed	Human Cdt1 lacking the evolutionarily conserved region that interacts with MCM2-7 is capable of inducing re-replication.	MCM6 CDT1 CCNA2	2.80e-07	6	85	3	18184650
Pubmed	Inhibition of protein kinase C by a synthetic peptide corresponding to cytoplasmic domain residues 828-848 of the human immunodeficiency virus type 1 envelope glycoprotein.	PRKCD PRKCE PRKCI	1.17e-06	9	85	3	7850771
Pubmed	Human immunodeficiency virus-1 recombinant gp120 induces changes in protein kinase C isozymes--a preliminary report.	PRKCD PRKCE PRKCI	1.17e-06	9	85	3	8206685
Pubmed	Regulation of HIV-1 gag protein subcellular targeting by protein kinase C.	PRKCD PRKCE PRKCI	1.17e-06	9	85	3	7876252
Pubmed	Phosphorylation of HIV-1 gag proteins by protein kinase C.	PRKCD PRKCE PRKCI	1.17e-06	9	85	3	8473314
Pubmed	The phorbol ester TPA strongly inhibits HIV-1-induced syncytia formation but enhances virus production: possible involvement of protein kinase C pathway.	PRKCD PRKCE PRKCI	1.67e-06	10	85	3	1970444
Pubmed	Human immunodeficiency virus induces phosphorylation of its cell surface receptor.	PRKCD PRKCE PRKCI	1.67e-06	10	85	3	3259291
Pubmed	Effect of serine and tyrosine phosphorylation on retroviral proteinase substrates.	PRKCD PRKCE PRKCI	1.67e-06	10	85	3	10491200
Pubmed	Inhibition of protein kinase C and anti-CD3-induced Ca2+ influx in Jurkat T cells by a synthetic peptide with sequence identity to HIV-1 gp41.	PRKCD PRKCE PRKCI	1.67e-06	10	85	3	2139676
Pubmed	Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol.	PRKCD PRKCE PRKCI	2.29e-06	11	85	3	14613966
Pubmed	IL-16- and other CD4 ligand-induced migration is dependent upon protein kinase C.	PRKCD PRKCE PRKCI	2.29e-06	11	85	3	8599832
Pubmed	Trans-activation of HIV-1 LTR-directed gene expression by tat requires protein kinase C.	PRKCD PRKCE PRKCI	2.29e-06	11	85	3	2182321
Pubmed	In vitro phosphorylation of human immunodeficiency virus type 1 Tat protein by protein kinase C: evidence for the phosphorylation of amino acid residue serine-46.	PRKCD PRKCE PRKCI	2.29e-06	11	85	3	8914829
Pubmed	Expression profile of protein kinase C isozymes in preimplantation mouse development.	PRKCD PRKCE PRKCI	2.29e-06	11	85	3	16183862
Pubmed	Involvement of protein kinase C in HIV-1 gp120-induced apoptosis in primary endothelium.	PRKCD PRKCE PRKCI	3.05e-06	12	85	3	11141237
Pubmed	HIV-1 Tat and AIDS-associated cancer: targeting the cellular anti-cancer barrier?	PRKCD PRKCE PRKCI	3.05e-06	12	85	3	18577246
Pubmed	c-FLIPL regulates PKC via AP-2 to inhibit Bax-mediated apoptosis induced by HIV-1 gp120 in Jurkat cells.	PRKCD PRKCE PRKCI	3.05e-06	12	85	3	19363595
Pubmed	HIV-1 Tat protein induces interleukin-10 in human peripheral blood monocytes: involvement of protein kinase C-betaII and -delta.	PRKCD PRKCE PRKCI	3.05e-06	12	85	3	11919157
Pubmed	HIV-1 reverse transcriptase is phosphorylated in vitro and in a cellular system.	PRKCD PRKCE PRKCI	3.96e-06	13	85	3	10641798
Pubmed	EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland.	PRKCD PRKCE PRKCI	3.96e-06	13	85	3	12761849
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ACSL3 MYO5A NOL6 XRN1 CPSF1 DHX57 MCM6 TTF1 MOV10 USP47	4.49e-06	653	85	10	22586326
Pubmed	HIV-1 envelope glycoproteins induce activation of activated protein-1 in CD4+ T cells.	PRKCD PRKCE PRKCI	5.03e-06	14	85	3	7642615
Pubmed	The divergent roles of protein kinase C epsilon and delta in simulated ischaemia-reperfusion injury in human myocardium.	PRKCD PRKCE	5.90e-06	2	85	2	19248786
Pubmed	Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6.	MCM6 CDT1	5.90e-06	2	85	2	20202939
Pubmed	Induction of neurites by the regulatory domains of PKCdelta and epsilon is counteracted by PKC catalytic activity and by the RhoA pathway.	PRKCD PRKCE	5.90e-06	2	85	2	14720513
Pubmed	Human thrombopoiesis depends on Protein kinase Cδ/protein kinase Cε functional couple.	PRKCD PRKCE	5.90e-06	2	85	2	27081176
Pubmed	Distinct contribution of protein kinase Cδ and protein kinase Cε in the lifespan and immune response of human blood monocyte subpopulations.	PRKCD PRKCE	5.90e-06	2	85	2	25322815
Pubmed	Bryostatin-1 attenuates TNF-induced epithelial barrier dysfunction: role of novel PKC isozymes.	PRKCD PRKCE	5.90e-06	2	85	2	12505880
Pubmed	Protein kinase D1 mediates NF-kappaB activation induced by cholecystokinin and cholinergic signaling in pancreatic acinar cells.	PRKCD PRKCE	5.90e-06	2	85	2	18845574
Pubmed	Overexpressed protein kinase C-delta and -epsilon subtypes in NIH 3T3 cells exhibit differential subcellular localization and differential regulation of sodium-dependent phosphate uptake.	PRKCD PRKCE	5.90e-06	2	85	2	8106444
Pubmed	Importance of C1B domain for lipid messenger-induced targeting of protein kinase C.	PRKCD PRKCE	5.90e-06	2	85	2	11877428
Pubmed	PKC{delta} is activated in a dietary model of steatohepatitis and regulates endoplasmic reticulum stress and cell death.	GPT PRKCD	5.90e-06	2	85	2	20971848
Pubmed	The interacting domains of hCdt1 and hMcm6 involved in the chromatin loading of the MCM complex in human cells.	MCM6 CDT1	5.90e-06	2	85	2	21099365
Pubmed	Diverse roles for protein kinase C delta and protein kinase C epsilon in the generation of high-fat-diet-induced glucose intolerance in mice: regulation of lipogenesis by protein kinase C delta.	PRKCD PRKCE	5.90e-06	2	85	2	19809797
Pubmed	Subcellular localization of protein kinase C delta and epsilon affects transcriptional and post-transcriptional processes in four-cell mouse embryos.	PRKCD PRKCE	5.90e-06	2	85	2	16183863
Pubmed	Cellular protein kinase C isozyme regulation by exogenously delivered physiological disulfides--implications of oxidative protein kinase C regulation to cancer prevention.	PRKCD PRKCE	5.90e-06	2	85	2	14656938
Pubmed	Structural insights into the Cdt1-mediated MCM2-7 chromatin loading.	MCM6 CDT1	5.90e-06	2	85	2	22140117
Pubmed	PKCδ and ε regulate the morphological integrity of the ER-Golgi intermediate compartment (ERGIC) but not the anterograde and retrograde transports via the Golgi apparatus.	PRKCD PRKCE	5.90e-06	2	85	2	22326427
Pubmed	Long chain n-3 polyunsaturated fatty acids increase the efficacy of docetaxel in mammary cancer cells by downregulating Akt and PKCε/δ-induced ERK pathways.	PRKCD PRKCE	5.90e-06	2	85	2	26821209
Pubmed	Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-kappa B binding and protein kinase C activity in primary human astrocytes.	PRKCD PRKCE PRKCI	6.28e-06	15	85	3	8627654
Pubmed	HIV envelope gp120 activates human arterial smooth muscle cells.	PRKCD PRKCE PRKCI	6.28e-06	15	85	3	11504923
Pubmed	A synthetic peptide with sequence identity to the transmembrane protein GP41 of HIV-1 inhibits distinct lymphocyte activation pathways dependent on protein kinase C and intracellular calcium influx.	PRKCD PRKCE PRKCI	7.71e-06	16	85	3	1832084
Pubmed	[HIV-1 Tat protein induces IL-10 production by human monocytes: implications of the PKC and calcium pathway].	PRKCD PRKCE PRKCI	7.71e-06	16	85	3	11833470
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF7 PRAMEF12 PRAMEF8	9.35e-06	17	85	3	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF7 PRAMEF12 PRAMEF8	9.35e-06	17	85	3	37781892
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF7 PRAMEF12 PRAMEF8	1.12e-05	18	85	3	23894331
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF7 PRAMEF12 PRAMEF8	1.12e-05	18	85	3	12890732
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF7 PRAMEF12 PRAMEF8	1.12e-05	18	85	3	29731491
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF7 PRAMEF12 PRAMEF8	1.12e-05	18	85	3	14675769
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF7 PRAMEF12 PRAMEF8	1.12e-05	18	85	3	39181896
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF7 PRAMEF12 PRAMEF8	1.33e-05	19	85	3	28604677
Pubmed	Tat protein of human immunodeficiency virus type 1 induces interleukin-10 in human peripheral blood monocytes: implication of protein kinase C-dependent pathway.	PRKCD PRKCE PRKCI	1.56e-05	20	85	3	11044099
Pubmed	Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.	PRAMEF7 PRAMEF12 PRAMEF8	1.56e-05	20	85	3	26694250
Pubmed	Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.	PRAMEF7 PRAMEF12 PRAMEF8	1.56e-05	20	85	3	16580637
Pubmed	Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.	PRAMEF7 PRAMEF12 PRAMEF8	1.56e-05	20	85	3	21425410
Pubmed	Proteomic analysis of livers from fat-fed mice deficient in either PKCδ or PKCε identifies Htatip2 as a regulator of lipid metabolism.	PRKCD PRKCE	1.77e-05	3	85	2	25175814
Pubmed	Regulation of tumor suppressor PDCD4 by novel protein kinase C isoforms.	PRKCD PRKCE	1.77e-05	3	85	2	20471435
Pubmed	Caenorhabditis elegans geminin homologue participates in cell cycle regulation and germ line development.	MCM6 CDT1	1.77e-05	3	85	2	15811859
Pubmed	Human Rab small GTPase- and class V myosin-mediated membrane tethering in a chemically defined reconstitution system.	MYO5A MYO5B	1.77e-05	3	85	2	28939769
Pubmed	G alpha(q)-coupled receptors in human atrium function through protein kinase C epsilon and delta.	PRKCD PRKCE	1.77e-05	3	85	2	15698833
Pubmed	The temporal and spatial expression pattern of myosin Va, Vb and VI in the mouse ovary.	MYO5A MYO5B	1.77e-05	3	85	2	16713372
Pubmed	Activated PKC{delta} and PKC{epsilon} inhibit epithelial chloride secretion response to cAMP via inducing internalization of the Na+-K+-2Cl- cotransporter NKCC1.	PRKCD PRKCE	1.77e-05	3	85	2	20732874
Pubmed	Role for myosin-V motor proteins in the selective delivery of Kv channel isoforms to the membrane surface of cardiac myocytes.	MYO5A MYO5B	1.77e-05	3	85	2	24508725
Pubmed	Cdc42 is involved in PKCepsilon- and delta-induced neurite outgrowth and stress fibre dismantling.	PRKCD PRKCE	1.77e-05	3	85	2	16930532
Pubmed	nPKCepsilon, a P2Y2-R downstream effector in regulated mucin secretion from airway goblet cells.	PRKCD PRKCE	1.77e-05	3	85	2	17728398
Pubmed	Structural insights into the globular tails of the human type v myosins Myo5a, Myo5b, And Myo5c.	MYO5A MYO5B	1.77e-05	3	85	2	24339992
Pubmed	Protein kinase Cepsilon (PKCepsilon) and Src control PKCdelta activation loop phosphorylation in cardiomyocytes.	PRKCD PRKCE	1.77e-05	3	85	2	17569658
Pubmed	Structural basis for inhibition of the replication licensing factor Cdt1 by geminin.	MCM6 CDT1	1.77e-05	3	85	2	15286659
Pubmed	Protein kinase C isoforms α, δ and ε are differentially expressed in mouse ovaries at different stages of postnatal development.	PRKCD PRKCE	1.77e-05	3	85	2	25491605
Pubmed	Flavin-Containing Monooxygenase 3 Reduces Endoplasmic Reticulum Stress in Lipid-Treated Hepatocytes.	PRKCD PRKCE	1.77e-05	3	85	2	26886171
Pubmed	Phorbol ester-stimulated NF-kappaB-dependent transcription: roles for isoforms of novel protein kinase C.	PRKCD PRKCE	1.77e-05	3	85	2	18436431
Pubmed	Structural insights into functional overlapping and differentiation among myosin V motors.	MYO5A MYO5B	1.77e-05	3	85	2	24097982
Pubmed	Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity.	MCM6 CDT1	1.77e-05	3	85	2	12192004
Pubmed	Urokinase plasminogen activator inhibits HIV virion release from macrophage-differentiated chronically infected cells via activation of RhoA and PKCε.	PRKCD PRKCE	1.77e-05	3	85	2	21858203
Pubmed	Differential roles of the PKC novel isoforms, PKCdelta and PKCepsilon, in mouse and human platelets.	PRKCD PRKCE	1.77e-05	3	85	2	19030108
Pubmed	PKC mediates fluctuant ERK-paxillin signaling for hepatocyte growth factor-induced migration of hepatoma cell HepG2.	PRKCD PRKCE	1.77e-05	3	85	2	23524339
Pubmed	Protein kinase C negatively regulates Akt activity and modifies UVC-induced apoptosis in mouse keratinocytes.	PRKCD PRKCE	1.77e-05	3	85	2	16338928
Pubmed	Differential modulation of unapposed connexin 43 hemichannel electrical conductance by protein kinase C isoforms.	PRKCD PRKCE	1.77e-05	3	85	2	18172602
Pubmed	alpha 1 Connexin (connexin43) gap junctions and activities of cAMP-dependent protein kinase and protein kinase C in developing mouse heart.	PRKCD PRKCE	1.77e-05	3	85	2	11803573
Pubmed	Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-alpha, and -epsilon and -zeta isoforms in PC12 cells.	PRKCD PRKCE PRKCI	1.82e-05	21	85	3	9446795
Pubmed	The human immunodeficiency virus coat protein gp120 promotes forward trafficking and surface clustering of NMDA receptors in membrane microdomains.	PRKCD PRKCE PRKCI	1.82e-05	21	85	3	22114277
Pubmed	Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase C- and cAMP-dependent protein kinase pathways.	PRKCD PRKCE PRKCI	1.82e-05	21	85	3	9671211
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF7 PRAMEF12 PRAMEF8	2.10e-05	22	85	3	31729367
Pubmed	HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes.	PRKCD PRKCE PRKCI	2.10e-05	22	85	3	11154208
Pubmed	The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix.	PRKCD PRKCE PRKCI	2.10e-05	22	85	3	9151826
Pubmed	Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.	PRAMEF7 PRAMEF12 PRAMEF8	2.41e-05	23	85	3	19480014
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	KIF20A DCAF1 ACSL3 MYO5A MARS1 NOL6 XRN1 CPSF1 PRKCD DHX57 MCM6 ECM1 MOV10	2.41e-05	1353	85	13	29467282
Pubmed	Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.	PRKCD PRKCE PRKCI	2.75e-05	24	85	3	10843712
Pubmed	Signalling crosstalk in FGF2-mediated protection of endothelial cells from HIV-gp120.	PRKCD PRKCE PRKCI	3.12e-05	25	85	3	15689238
Pubmed	MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.	PRAMEF7 PRAMEF12 PRAMEF8	3.12e-05	25	85	3	37451217
Pubmed	Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.	PRAMEF7 PRAMEF12 PRAMEF8	3.12e-05	25	85	3	12620990
Pubmed	Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.	PRAMEF7 PRAMEF12 PRAMEF8	3.52e-05	26	85	3	18500982
Pubmed	Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication.	MCM6 CDT1 CCNA2	3.52e-05	26	85	3	11931757
Pubmed	Protein kinase C regulates human pluripotent stem cell self-renewal.	PRKCD PRKCE	3.53e-05	4	85	2	23349801
Pubmed	Interaction of connexin43 and protein kinase C-delta during FGF2 signaling.	PRKCD PRKCE	3.53e-05	4	85	2	20338032
Pubmed	Dual Regulation of Spine-Specific and Synapse-to-Nucleus Signaling by PKCδ during Plasticity.	PRKCD PRKCE	3.53e-05	4	85	2	37277178
Pubmed	Structural basis of myosin V Rab GTPase-dependent cargo recognition.	MYO5A MYO5B	3.53e-05	4	85	2	24248336
Pubmed	Alternative splicing in class V myosins determines association with Rab10.	MYO5A MYO5B	3.53e-05	4	85	2	19008234
Pubmed	Combined cardiomyocyte PKCδ and PKCε gene deletion uncovers their central role in restraining developmental and reactive heart growth.	PRKCD PRKCE	3.53e-05	4	85	2	25900833
Pubmed	Emergence of structure through protein-protein interactions and pH changes in dually predicted coiled-coil and disordered regions of centrosomal proteins.	BRCA1 CCNA2	3.53e-05	4	85	2	25091198
Interaction	H1-1 interactions	KIF20A DCAF1 SCN4A TRMT1 PRKCD DHX57 PRKCE MCM6 DLEC1 TTF1 MOV10 CCNA2	9.45e-07	507	82	12	int:H1-1
Cytoband	1p36.21	PRAMEF7 PRAMEF12 PRAMEF8	2.32e-04	63	86	3	1p36.21
Cytoband	18q21	MRO MYO5B	5.20e-04	18	86	2	18q21
GeneFamily	Myosins, class V	MYO5A MYO5B	2.62e-05	3	54	2	1100
GeneFamily	PRAME family	PRAMEF7 PRAMEF12 PRAMEF8	4.88e-05	24	54	3	686
GeneFamily	C2 domain containing protein kinases	PRKCD PRKCE	3.88e-04	10	54	2	835
GeneFamily	Dyneins, axonemal	DNAH10 DNAH17	1.16e-03	17	54	2	536
GeneFamily	Neuroblastoma breakpoint family	NBPF12 NBPF11	2.13e-03	23	54	2	662
GeneFamily	Potassium voltage-gated channels	KCNB1 KCND1	6.35e-03	40	54	2	274
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	MIER3 TTF1	1.09e-02	53	54	2	532
Coexpression	ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_6HR	KIF20A BRCA1 MCM6 CDT1 CCNA2	8.04e-06	84	85	5	M2606
Coexpression	WHITFIELD_CELL_CYCLE_LITERATURE	KIF20A BRCA1 MCM6 CCNA2	1.27e-05	44	85	4	M2066
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRCA1 DNAH10 MRO DHX57 CDT1 MOV10	8.19e-07	165	86	6	1703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	1.04e-06	172	86	6	6fcc16f1067672967ecbcdfdc727649ae9891dd9
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF20A FREM2 ARHGEF39 PODN MSLN IGDCC4	1.27e-06	178	86	6	c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	1.40e-06	181	86	6	e4dbc09f0210de465d8347969b301c22463a2b7d
ToppCell	Healthy_Control-Lymphoid-T-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	1.40e-06	181	86	6	ac1ee313910c05b1b3cb497bae14565464919c21
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF20A BRCA1 ARHGEF39 MCM6 ATP4A CCNA2	1.50e-06	183	86	6	6c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPLD1 KCND1 GPR153 ALPK3 IGDCC4 CFAP65	1.55e-06	184	86	6	6b0c110d8930df99043c3b99cf4d873985126960
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPLD1 KCND1 GPR153 ALPK3 IGDCC4 CFAP65	1.55e-06	184	86	6	35928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCell	Severe_COVID-19-Myeloid-proliferating_Myeloid_cells\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	KIF20A BRCA1 ARHGEF39 CDT1 PCSK9 CCNA2	2.04e-06	193	86	6	0d85025690c9cd545cba30abc38acbdd6a39b153
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF20A BRCA1 ARHGEF39 CDT1 PCSK9 CCNA2	2.10e-06	194	86	6	cb39850e9577015b6b9834e98c36b412bae7d462
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF20A BRCA1 ARHGEF39 CDT1 PCSK9 CCNA2	2.10e-06	194	86	6	408597c9aa302a44b112c1d612c21fbb0227a82a
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KIF20A BRCA1 ARHGEF39 CDT1 PCSK9 CCNA2	2.10e-06	194	86	6	193cc20fefbd795a4ad59e401a95af47d30603e7
ToppCell	BAL-Severe-Myeloid-Myeloid\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF20A BRCA1 ARHGEF39 CDT1 PCSK9 CCNA2	2.10e-06	194	86	6	2360b5f995b360419de41612368cab9fb61781a1
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	KIF20A BRCA1 ARHGEF39 CDT1 PCSK9 CCNA2	2.10e-06	194	86	6	903ae11708b0cb24538c6982abd57fe6fa95b8d3
ToppCell	BAL-Severe-Myeloid-Myeloid\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	KIF20A BRCA1 ARHGEF39 CDT1 PCSK9 CCNA2	2.10e-06	194	86	6	58406502a8cbcc3037f79a1b6a683df408297ae5
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	2.16e-06	195	86	6	c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	2.23e-06	196	86	6	6d80e23f6a1725a3f5ea7263233c55c2ea56f977
ToppCell	BAL-Control-Myeloid-Myeloid\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	2.23e-06	196	86	6	bf1d3fae8c01bb3d17c2dafad92b94937c663acd
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	2.23e-06	196	86	6	3dd7ed1dfac8d90c8a44f0ae00128bb46d9ef496
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	2.23e-06	196	86	6	4f649e3bfd21f21682678828673843a7d51c4ff2
ToppCell	BAL-Control-Myeloid-Myeloid\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	2.23e-06	196	86	6	799c290fb3dfacb666dd0dc3c43ec8a86b697ec7
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	2.23e-06	196	86	6	0c003a767c3b58605099dab64b9df0d8e5d8bc4b
ToppCell	Healthy-T/NK_proliferative\|World / disease group, cell group and cell class	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	2.29e-06	197	86	6	e90be1e7e02f736b6aab14010a912b592d6f1e80
ToppCell	Control-Myeloid-proliferating_Myeloid_cells\|Control / Disease group,lineage and cell class （2021.01.30）	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	2.29e-06	197	86	6	ddbe3fe078766bb55f0d7ca1aeb8f9e4aa696d8e
ToppCell	COVID-19_Moderate-T/NK_proliferative\|COVID-19_Moderate / disease group, cell group and cell class	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	2.36e-06	198	86	6	166c000fb0e19602ffdd8bf2b2f19be2c6df96a6
ToppCell	COVID-19_Moderate-T/NK_proliferative\|World / disease group, cell group and cell class	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	2.36e-06	198	86	6	bf0131fbca6032e1aab4aa807f8c1d3be689cb7f
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19-Stem_cells-Stem_cells\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	KIF20A BRCA1 ARHGEF39 ADGRV1 CPT2 CCNA2	2.36e-06	198	86	6	50f236ab7ef6f00721f6cd714e3eee183077beeb
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|bone_marrow / Manually curated celltypes from each tissue	KIF20A PRAM1 BRCA1 MCM6 CDT1 CCNA2	2.36e-06	198	86	6	5c92687b853ebb00960adbef6552f9d460bc6886
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19-Stem_cells\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	KIF20A BRCA1 ARHGEF39 ADGRV1 CPT2 CCNA2	2.36e-06	198	86	6	dc0c6189ff9dd76675f63acf1cbc7dda60e75f3f
ToppCell	cycling_basal_cell\|World / shred by cell class for turbinate	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	2.36e-06	198	86	6	e86c1224f5b0890a50a25257628e90c790aae7cd
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	2.36e-06	198	86	6	bcfe7b6d91f2e2f145cb2660b65fd2a6c1134b86
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DNAH10 DLEC1 ECM1 ANKFN1 MSLN CFAP65	2.50e-06	200	86	6	da12821e8a0657869ca0f75d351cce2d7605a505
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF20A BRCA1 ARHGEF39 CDT1 ECM1 CCNA2	2.50e-06	200	86	6	1fbed5967fc1922efe4a98f5760ad74fce210c52
ToppCell	3'_v3-Lung-Lymphocytic_NK-Cycling_NK\|Lung / Manually curated celltypes from each tissue	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	2.50e-06	200	86	6	381bafdde6492f020ae93ab8fffa6215c631c570
ToppCell	Biopsy_IPF-Immune-Proliferating_Macrophages\|Biopsy_IPF / Sample group, Lineage and Cell type	KIF20A BRCA1 ARHGEF39 MCM6 CDT1 CCNA2	2.50e-06	200	86	6	8abb2c25422717e994468ac02d8260344341467f
ToppCell	LPS_IL1RA_TNF-Epithelial_airway\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DNAH10 DLEC1 ECM1 ANKFN1 MSLN CFAP65	2.50e-06	200	86	6	72c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH10 ANKEF1 DLEC1 ANKFN1 CFAP65	1.11e-05	151	86	5	81cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH10 ANKEF1 DLEC1 ANKFN1 CFAP65	1.11e-05	151	86	5	9cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH10 ANKEF1 DLEC1 ANKFN1 CFAP65	1.23e-05	154	86	5	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH10 ANKEF1 DLEC1 ANKFN1 CFAP65	1.23e-05	154	86	5	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH10 ANKEF1 DLEC1 ANKFN1 CFAP65	1.27e-05	155	86	5	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH10 ANKEF1 DLEC1 ANKFN1 CFAP65	1.27e-05	155	86	5	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	3'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C17orf113 FOCAD GPLD1 FCGBP DLEC1	1.43e-05	159	86	5	6ec5489d55667e53bd9c021ada7de458bfef43a3
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNT2 DNAH10 AADACL2 ADGRV1 WDR17	1.47e-05	160	86	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNT2 DNAH10 AADACL2 ADGRV1 WDR17	1.47e-05	160	86	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	367C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	KIF20A DNAH10 MYO5B AADACL2 ANKEF1	1.52e-05	161	86	5	c61283c301a87bb802f6f8ce79c26067032dd7d9
ToppCell	367C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	KIF20A DNAH10 MYO5B AADACL2 ANKEF1	1.52e-05	161	86	5	9864d8b0929dacf4be7a4e97d2527ac3120ea264
ToppCell	3'-Adult-Distal_Rectal-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C17orf113 FOCAD GPLD1 FCGBP DLEC1	1.57e-05	162	86	5	075f73ff10e1a7f5695e014e47acc4db513e9cfb
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NOL6 TMEM38A CDT1 ANKFN1 PCSK9	1.61e-05	163	86	5	360cd65decda24853124f33a174f5224d7f3ce23
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NOL6 TMEM38A CDT1 ANKFN1 PCSK9	1.61e-05	163	86	5	b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KCND1 AADACL2 XRN1 GBP3 MCRS1	1.61e-05	163	86	5	d005115aa1e1458b51de7eb719794617a4168608
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FREM2 ANKEF1 ANKFN1 MSLN CFAP65	1.66e-05	164	86	5	e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF20A BRCA1 ARHGEF39 CDT1 CCNA2	2.21e-05	174	86	5	c26eac176e9b0cba385630fdc60e0314a4e4caac
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	CDT1 ADGRV1 PCSK9 CCNA2 CFAP65	2.27e-05	175	86	5	fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|368C / Donor, Lineage, Cell class and subclass (all cells)	CDT1 ADGRV1 PCSK9 CCNA2 CFAP65	2.27e-05	175	86	5	36c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KCNT2 BRCA1 ARHGEF39 MCM6 CDT1	2.40e-05	177	86	5	f925a15d2162d166a5b60edac3517c6b2d6cfbea
ToppCell	Dividing_Macrophages-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	KIF20A BRCA1 ARHGEF39 CDT1 CCNA2	2.46e-05	178	86	5	1893fadac2ec3d5de0a641e57b7b2f962012a9ba
ToppCell	10x5'-blood-Lymphocytic_NK-Cycling_NK\|blood / Manually curated celltypes from each tissue	KIF20A BRCA1 ARHGEF39 CDT1 CCNA2	2.53e-05	179	86	5	c93711273055a999335ba8d0f6500e4549f46cec
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KIF20A ALPK3 MCM6 CDT1 CCNA2	2.60e-05	180	86	5	42f48e646fc6e72ad3cce72409ace3a0b64020a2
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF20A BRCA1 ARHGEF39 CDT1 CCNA2	2.60e-05	180	86	5	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	P28-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KIF20A BRCA1 ARHGEF39 MCM6 CCNA2	2.67e-05	181	86	5	e482fd116c00ff4d8db7be3c06b1bd1ffa2d479d
ToppCell	P28-Endothelial-proliferative_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KIF20A BRCA1 ARHGEF39 MCM6 CCNA2	2.67e-05	181	86	5	2be3d44619adb25d339e7a27b500a56e07e8de01
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF20A ARHGEF39 MCM6 CDT1 CCNA2	2.67e-05	181	86	5	73b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	DNAH10 AADACL2 DLEC1 ANKFN1 CFAP65	2.74e-05	182	86	5	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	droplet-Lung-nan-18m-Myeloid-Proliferating_Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRCA1 ARHGEF39 MCM6 ATP4A CCNA2	2.74e-05	182	86	5	11494a66d986297b837332ee9d382b71b9f22591
ToppCell	Control-T/NK_proliferative\|Control / Disease group and Cell class	KIF20A BRCA1 CDT1 ECM1 CCNA2	2.81e-05	183	86	5	09c2b4e630f1c338f02c1242e3598e870d6b0a28
ToppCell	IIF-Lymphocyte-T_NK-T_NK_proliferative\|IIF / Disease, Lineage and Cell Type	KIF20A BRCA1 MCM6 CDT1 CCNA2	2.89e-05	184	86	5	ab8b45ce40e8c5f66e5c23332a591b4f9cba4ce1
ToppCell	Dividing_Macrophages-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	KIF20A BRCA1 ARHGEF39 CDT1 CCNA2	2.89e-05	184	86	5	f15ce786d25c6546804a6d1efcc2ad645f2ef54e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 DNAH10 MRO ALPK3 CFAP65	2.96e-05	185	86	5	05bc89a566b0db90ae06506e067190a4739a0974
ToppCell	droplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF20A BRCA1 MCM6 CDT1 CCNA2	2.96e-05	185	86	5	57c1eb50a4456d20953e48d5dc3b0ea3d0d81b6d
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_NK-Cycling_NK\|GI_small-bowel / Manually curated celltypes from each tissue	KIF20A FCGBP ARHGEF39 CDT1 CCNA2	3.12e-05	187	86	5	265c690c2921fd201361a0ec8bc4d2a996fbcaf4
ToppCell	droplet-Spleen-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF20A BRCA1 PODN GDF3 ATP4A	3.20e-05	188	86	5	1a3f95b4fd7611c634666761ddf21f1e58e56af8
ToppCell	PBMC-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	BRCA1 GPR153 MCM6 CDT1 CCNA2	3.28e-05	189	86	5	946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCell	Dividing_Macrophages-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	KIF20A BRCA1 ARHGEF39 CDT1 CCNA2	3.28e-05	189	86	5	d4e88a3e50499d683e3db38aee04490146fe30bb
ToppCell	Int-URO-Lymphocyte-T_NK-T_NK_proliferative\|Int-URO / Disease, Lineage and Cell Type	KIF20A BRCA1 MCM6 CDT1 CCNA2	3.36e-05	190	86	5	005967c540418b85311308072a07c684f4296aef
ToppCell	(02)_Cycling_Basal_(regeneration)\|World / shred by cell type and Timepoint	KIF20A MCM6 CDT1 ECM1 CCNA2	3.36e-05	190	86	5	53f017a11ca5ebe9025558e12cedc409cab2e5aa
ToppCell	Dividing_Macrophages-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	KIF20A BRCA1 ARHGEF39 CDT1 CCNA2	3.45e-05	191	86	5	3e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T\|bone_marrow / Manually curated celltypes from each tissue	KIF20A BRCA1 MCM6 CDT1 CCNA2	3.45e-05	191	86	5	210a0f1a71df2508cbfc73d6868a2122338b9a1c
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KIF20A FREM2 ARHGEF39 ADGRV1 CCNA2	3.45e-05	191	86	5	39220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH10 AADACL2 DLEC1 ANKFN1 CFAP65	3.45e-05	191	86	5	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF20A BRCA1 ARHGEF39 CDT1 CCNA2	3.45e-05	191	86	5	50854384fdaa0efa2e3227659d544ed09ac102f2
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH10 AADACL2 DLEC1 ANKFN1 CFAP65	3.45e-05	191	86	5	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic-lymphocyte-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	KIF20A BRCA1 MCM6 CDT1 CCNA2	3.45e-05	191	86	5	56b45259dfc38bd5ea43b0e3adf47e7e2c043a5d
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH10 AADACL2 DLEC1 ANKFN1 CFAP65	3.45e-05	191	86	5	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	Dividing_Macrophages-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	KIF20A BRCA1 ARHGEF39 CDT1 CCNA2	3.54e-05	192	86	5	741bd0c2b0a7ce3fcb1610ce8bdacaf9a803c212
ToppCell	facs-Thymus-Flowthrough-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF20A BRCA1 MCM6 CDT1 CCNA2	3.54e-05	192	86	5	e8d47504b744040a762ec9b670a66cc060b2ae86
ToppCell	Control-Lymphoid-Proliferating_CD4_T_cells\|Control / Condition, Lineage and Cell class	KIF20A BRCA1 ARHGEF39 CDT1 CCNA2	3.62e-05	193	86	5	33d409d6ed1c606337248587ad997ac5f67f081d
ToppCell	control-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KIF20A BRCA1 MCM6 CDT1 CCNA2	3.62e-05	193	86	5	ecb4018a47d9a82bb999e0bc8b3dceabd97d1f0d
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF20A BRCA1 MCM6 CDT1 CCNA2	3.71e-05	194	86	5	f39a471293ecc5c5967b00e772b8f48ebc9affbe
ToppCell	P03-Endothelial-proliferative_endothelial_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KIF20A BRCA1 MCM6 CDT1 CCNA2	3.71e-05	194	86	5	22bcfb0f3f73608feb22c0847ab4d34f87aeede0
ToppCell	3'_v3-Lung-Myeloid_Mac-Cycling_Myeloid-Mac\|Lung / Manually curated celltypes from each tissue	KIF20A BRCA1 CDT1 ECM1 CCNA2	3.71e-05	194	86	5	a8ae49157ca3f9e8b3f1750a995aee012dc859b6
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	KIF20A FREM2 ARHGEF39 ADGRV1 CCNA2	3.71e-05	194	86	5	c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF20A BRCA1 ARHGEF39 CDT1 CCNA2	3.71e-05	194	86	5	1a2090e997c70433d07f56bf7cb0a50c4151118c
ToppCell	P03-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KIF20A BRCA1 MCM6 CDT1 CCNA2	3.71e-05	194	86	5	5e56ce9b9fe0721be3a9e6efe1422599bb867721
ToppCell	wk_20-22-Hematologic_Lymphocytic-B-Pro-B\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	KIF20A BRCA1 MCM6 CDT1 CCNA2	3.71e-05	194	86	5	3590ff471f74a361ee5bf02a58e3104cd3bf7d00
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	KIF20A BRCA1 ARHGEF39 CDT1 CCNA2	3.71e-05	194	86	5	f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell	Control-Lymphoid_T/NK-T/NK_proliferative\|Control / Disease group, lineage and cell class	KIF20A BRCA1 MCM6 CDT1 CCNA2	3.71e-05	194	86	5	9bbb124001fba7450f4639f47f9b720a483e7242
ToppCell	Control-Lymphocyte-T_NK-T_NK_proliferative\|Control / Disease, Lineage and Cell Type	KIF20A BRCA1 MCM6 CDT1 CCNA2	3.71e-05	194	86	5	844731b7943d1cfca819b7b89e4e62067bfa0230
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF20A BRCA1 ARHGEF39 CDT1 CCNA2	3.71e-05	194	86	5	6cc689595a182fbf685fa2f3b9c300f7170fb81f
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KIF20A BRCA1 MCM6 CDT1 CCNA2	3.71e-05	194	86	5	a75ecd0b0a928d4646602f7d16a645f6b3df3af5
Drug	dihydrosterculic acid	PRKCD PRKCE PRKCI CPT2	5.07e-07	18	84	4	CID000160788
Drug	25(OH) vitamin D3	MGAM GPT PRKCD PRKCE PRKCI CUBN PCSK9	1.39e-06	150	84	7	CID000001593
Drug	diazoxide	MGAM KCNT2 KCNB1 KCND1 GPT PRKCD PRKCE PRKCI	1.96e-06	227	84	8	CID000003019
Drug	ST638	GPLD1 PRKCD PRKCE MCRS1 PRKCI	5.26e-06	68	84	5	CID000005276
Drug	AC1L1J6W	PTGES2 GPT PRKCD PRKCE PRKCI CUBN IGDCC4	5.78e-06	186	84	7	CID000004894
Drug	NSC383468	GPT PRKCD PRKCE PRKCI PCSK9	6.08e-06	70	84	5	CID000343585
Drug	verapamil	MGAM KCNT2 KCNB1 MYO5A MYO5B KCND1 SCN4A PRKCD PRKCE PRKCI	1.29e-05	490	84	10	CID000002520
Drug	dansyl-DAG	PRKCD PRKCE PRKCI	2.13e-05	15	84	3	CID000129493
Drug	RK-1409B	PRKCD PRKCE PRKCI	2.13e-05	15	84	3	CID003036125
Drug	1-stearoyl-2-arachidonylglycerol	PRKCD PRKCE PRKCI	2.13e-05	15	84	3	CID006443869
Drug	tetraethylammonium	MGAM KCNB1 KCND1 SCN4A PRKCD PRKCE PRKCI	2.70e-05	236	84	7	CID000005413
Drug	AC1L1JQC	PRKCD PRKCE PRKCI	3.17e-05	17	84	3	CID000005157
Drug	daphnoretin	PRKCD PRKCE PRKCI	3.17e-05	17	84	3	CID005281406
Drug	strontium chromate	MGAM MYO5A PRKCD PRKCE PRKCI	3.30e-05	99	84	5	CID000024599
Drug	diradylglycerol	GPLD1 PRKCD PRKCE PRKCI	3.77e-05	51	84	4	CID006437874
Drug	dipalmitin	PRKCD PRKCE PRKCI	3.80e-05	18	84	3	CID000068149
Drug	Cgp-42700	PRKCD PRKCE PRKCI	3.80e-05	18	84	3	CID000188390
Drug	TAPP-Br	PRKCD PRKCE PRKCI	4.50e-05	19	84	3	CID000160326
Drug	sapintoxin A	PRKCD PRKCE PRKCI	4.50e-05	19	84	3	CID000108085
Drug	1,2-diglyceride	GPLD1 PTGES2 PRKCD PRKCE PRKCI CPT2	4.68e-05	175	84	6	CID000192866
Drug	NSC755840	GPT PRKCD PRKCE PRKCI	4.74e-05	54	84	4	CID000002117
Drug	Cortisporin	GPLD1 PRKCD PRKCE PRKCI ADGRV1 GDF3	4.99e-05	177	84	6	CID000004454
Drug	HA1004	GPLD1 PTGES2 PRKCD PRKCE PRKCI	5.24e-05	109	84	5	CID000003546
Drug	AD 198	PRKCD PRKCE CPT2	5.28e-05	20	84	3	CID000127201
Drug	RHC 80267	GPLD1 PTGES2 PRKCD PRKCE PRKCI	5.97e-05	112	84	5	CID000005063
Drug	KS-619-1	PRKCD PRKCE PRKCI	6.14e-05	21	84	3	CID000128369
Drug	K-259-2	PRKCD PRKCE PRKCI	6.14e-05	21	84	3	CID006438946
Drug	debromoaplysiatoxin	PRKCD PRKCE PRKCI	6.14e-05	21	84	3	CID000002967
Drug	broussochalcone A	PRKCD PRKCE PRKCI	6.14e-05	21	84	3	CID006438825
Drug	MDL 27,032	PRKCD PRKCE PRKCI	6.14e-05	21	84	3	CID000163812
Drug	(?-Fluprostenol	PTGES2 PRKCD PRKCE PRKCI	7.66e-05	61	84	4	CID000003391
Drug	AC1L4NFY	PRKCD PRKCE PRKCI	8.13e-05	23	84	3	CID000160335
Drug	myristyl acetate	PRKCD PRKCE PRKCI CUBN	8.70e-05	63	84	4	CID000012531
Drug	Tridihexethyl chloride; Up 200; 11.4uM; HL60; HT_HG-U133A	PTGES2 ERAP2 GPR153 MCRS1 GNAT1 PADI2	8.77e-05	196	84	6	2964_UP
Drug	radicicol; Up 200; 0.1uM; PC3; HG-U133A	CPSF1 PRAMEF12 GNAT1 CUBN PADI2 ATP4A	9.02e-05	197	84	6	484_UP
Drug	D 609	GPLD1 PRKCD PRKCE PRKCI	9.25e-05	64	84	4	CID000002940
Drug	AC1L1ET5	GPLD1 PRKCD PRKCE PRKCI	9.83e-05	65	84	4	CID000002936
Drug	15-epi-lipoxin A4	GPLD1 PTGES2 PRKCD PRKCE PRKCI	1.12e-04	128	84	5	CID000003934
Drug	2-methylthioadenosine triphosphate	GPLD1 PRKCD PRKCE PRKCI	1.17e-04	68	84	4	CID000001581
Drug	AC1L1H7H	PTGES2 PRKCD PRKCE PRKCI	1.17e-04	68	84	4	CID000004009
Drug	R59949	GPLD1 PRKCD PRKCE PRKCI	1.31e-04	70	84	4	CID000657356
Drug	beta-tocopherol	PRKCD PRKCE PRKCI	1.33e-04	27	84	3	CID000008989
Drug	ilmofosine	PRKCD PRKCE PRKCI	1.33e-04	27	84	3	CID000055008
Drug	C15720	PRKCD PRKCE PRKCI	1.33e-04	27	84	3	CID000003979
Drug	pseudohypericin	PRKCD PRKCE PRKCI	1.33e-04	27	84	3	CID005281751
Drug	NSC-88947	MGAM GPT	1.34e-04	5	84	2	CID005351908
Drug	UCN-01-Me	PRKCD PRKCE	1.34e-04	5	84	2	CID000130373
Drug	calcium nitrate tetrahydrate	MGAM MARS1	1.34e-04	5	84	2	CID000026061
Drug	Barium permanganate	MGAM SCN4A PRKCD PRKCE PRKCI	1.35e-04	133	84	5	CID000024587
Drug	NSC107658	GPLD1 MYO5A MYO5B PRKCD PRKCE PRKCI MSLN	1.38e-04	306	84	7	CID000002919
Drug	methoxamine	PRKCD PRKCE PRKCI CDT1	1.39e-04	71	84	4	CID000006081
Drug	vanadyl	GPLD1 MGAM DNAH10 DNAH17 PRKCD PRKCE PRKCI	1.41e-04	307	84	7	CID000061671
Drug	bisindolylmaleimide II	PRKCD PRKCE PRKCI	1.48e-04	28	84	3	CID000002397
Drug	bisindolylmaleimide V	PRKCD PRKCE PRKCI	1.48e-04	28	84	3	CID000002400
Drug	aplysiatoxin	PRKCD PRKCE PRKCI	1.48e-04	28	84	3	CID000040465
Drug	HBDDE	PRKCD PRKCE PRKCI	1.48e-04	28	84	3	CID000003568
Drug	SC-10	PRKCD PRKCE PRKCI	1.48e-04	28	84	3	CID000005175
Drug	NCDC	PRKCD PRKCE PRKCI	1.48e-04	28	84	3	CID000001583
Drug	AC1Q6DXY	PRKCD PRKCE PRKCI	1.65e-04	29	84	3	CID000003719
Drug	AC1L1B58	PRKCD PRKCE PRKCI	1.65e-04	29	84	3	CID000001288
Drug	Polychlorinated biphenyls	PRKCD PRKCE PRKCI	1.65e-04	29	84	3	CID000006636
Drug	Methamphetamine	KIF20A FCGBP BRCA1 TMTC3 KCNB1 MYO5B GPT XRN1 TRMT1 SMPD4 PRKCD PRKCE CUBN MOV10 CCNA2	1.69e-04	1401	84	15	ctd:D008694
Drug	R59022	GPLD1 PRKCD PRKCE PRKCI	1.81e-04	76	84	4	CID000003012
Drug	9,11-octadecadienoic acid	PRKCD PRKCE PRKCI CPT2 CCNA2	1.83e-04	142	84	5	CID000074607
Drug	calcium sulfate	MGAM MARS1 CDT1	1.83e-04	30	84	3	CID000024497
Drug	Gf 109	PRKCD PRKCE PRKCI	1.83e-04	30	84	3	CID000196144
Drug	AC1L3G0K	PRKCD PRKCE PRKCI	1.83e-04	30	84	3	CID000114822
Drug	12-deoxyphorbol 13-phenylacetate	PRKCD PRKCE PRKCI	1.83e-04	30	84	3	CID000105100
Drug	methyl 2,5-dihydroxycinnamate	GPLD1 PRKCD PRKCE PRKCI	1.90e-04	77	84	4	CID000003248
Drug	trifluoperazine	MGAM MYO5A MYO5B PRKCD PRKCE PRKCI ATP4A	1.96e-04	324	84	7	CID000005566
Drug	6,9,12-octadecatrienoic acid	PRKCD PRKCE PRKCI CCNA2	2.00e-04	78	84	4	CID000003453
Drug	miltefosine	GPLD1 PRKCD PRKCE PRKCI	2.00e-04	78	84	4	CID000003599
Drug	AC1L1B9H	KCNB1 PRKCD PRKCE PRKCI	2.00e-04	78	84	4	CID000001341
Drug	talcum powder	MGAM MARS1	2.00e-04	6	84	2	CID000517272
Drug	2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one	PRKCD PRKCE	2.00e-04	6	84	2	ctd:C505456
Drug	N,n,n-tms	PRKCD PRKCE PRKCI	2.02e-04	31	84	3	CID006439410
Drug	orthovanadate	KIF20A GPLD1 MGAM DNAH17 ALPK3 PRKCD PRKCE PRKCI	2.04e-04	435	84	8	CID000061672
Drug	dihydrosphingosine	GPLD1 GPT PRKCD PRKCE PRKCI	2.08e-04	146	84	5	CID000003126
Drug	AC1NS1NG	MGAM PRKCD PRKCE PRKCI ADGRV1	2.15e-04	147	84	5	CID005327099
Drug	Sulcrate	GPLD1 MGAM MARS1 CDT1 GNAT1	2.22e-04	148	84	5	CID006398525
Drug	PPL-L-alanine	MGAM PRKCD PRKCE PRKCI	2.42e-04	82	84	4	CID000444773
Drug	AC1NPP2V	GPT PRKCD PRKCE PRKCI	2.42e-04	82	84	4	CID005207744
Drug	CGS 9343B	PRKCD PRKCE PRKCI	2.44e-04	33	84	3	CID000065909
Drug	naphthalenesulfonamide	PRKCD PRKCE PRKCI	2.44e-04	33	84	3	CID000163571
Drug	AC1L1FGW	PRKCD PRKCE PRKCI	2.44e-04	33	84	3	CID000003231
Drug	arachidonic acid trifluoromethyl ketone	GPLD1 PTGES2 PRKCD PRKCE PRKCI	2.58e-04	153	84	5	CID000002224
Drug	acetyl-L-carnitine	PRKCD PRKCE PRKCI CPT2	2.66e-04	84	84	4	CID000000001
Drug	UCN-01	BRCA1 PRKCD PRKCE PRKCI CCNA2	2.66e-04	154	84	5	CID000072271
Drug	AC1NSKHR	PRKCD PRKCE PRKCI	2.67e-04	34	84	3	CID005311362
Drug	h x mg	PRKCD PRKCE PRKCI	2.67e-04	34	84	3	CID000001380
Drug	4-O-methyl-TPA	PRKCD PRKCE PRKCI	2.67e-04	34	84	3	CID000072292
Drug	pinacidil	KCNB1 PRKCD PRKCE PRKCI	3.04e-04	87	84	4	CID000004826
Drug	tetracaine	SCN4A PRKCD PRKCE PRKCI	3.18e-04	88	84	4	CID000005411
Drug	eicosa-8,11,14-trienoic acid	PTGES2 PRKCD PRKCE PRKCI	3.18e-04	88	84	4	CID000003011
Drug	W7 hydrochloride	GPLD1 MGAM CAMKV PRKCD PRKCE PRKCI	3.28e-04	250	84	6	CID000005681
Drug	C6-ceramide	GPLD1 PRKCD PRKCE PRKCI	3.32e-04	89	84	4	CID000375405
Drug	GDP-b-S	GPLD1 PRKCD PRKCE PRKCI GNAT1	3.36e-04	162	84	5	CID000643998
Drug	baicalein	MGAM PRKCD PRKCE PRKCI CCNA2	3.36e-04	162	84	5	CID005281605
Drug	HOE 694	PRKCD PRKCE PRKCI	3.44e-04	37	84	3	CID000123840
Drug	iso-H7	PRKCD PRKCE PRKCI	3.44e-04	37	84	3	CID000001352
Disease	idiopathic dilated cardiomyopathy	MGAM AADACL2 DNAH17	5.66e-04	60	79	3	EFO_0009094
Disease	low density lipoprotein cholesterol measurement, body fat percentage	DNAH10 MCM6	9.38e-04	17	79	2	EFO_0004611, EFO_0007800
Disease	epilepsy (implicated_via_orthology)	KCNT2 TMTC3 SCN4A ATP4A	9.77e-04	163	79	4	DOID:1826 (implicated_via_orthology)
Disease	urinary microalbumin measurement	CRPPA CUBN	1.30e-03	20	79	2	EFO_0010967
Disease	complement factor H-like 1 protein measurement	FREM2 KCNT2	1.58e-03	22	79	2	EFO_0600092
Disease	upper face morphology measurement	DLEC1 ADGRV1 ANKFN1	2.27e-03	97	79	3	EFO_0010949

Protein segments in the cluster

Peptide	Gene	Start	Entry
PEIIDYLYETTLPLL	TTF1	821	Q15361
IPQYPLYSATLAELG	GPT	186	P24298
GEPLYNYASIRLPEE	EOGT	31	Q5NDL2
VLLYPGLQITDSYLP	AADACL2	216	Q6P093
PIYVINDIYPELEES	ADGRV1	2186	Q8WXG9
DLLSYYESPIQGVPD	ADGRV1	2406	Q8WXG9
GFGEVPEIIPLYLIY	ALPK3	1696	Q96L96
LPGLVLPYKYQVLAE	CDT1	181	Q9H211
LTKLGYPELINYTEP	ANKEF1	31	Q9NU02
YPELINYTEPINGLS	ANKEF1	36	Q9NU02
PPDYLIDPQILLCDY	CCM2L	46	Q9NUG4
ELIYGASQELLPYLE	ARHGEF39	71	Q8N4T4
PPAYLGQYESILDAL	C17orf113	306	A0A1B0GUU1
KGIILPELYLDPAYG	CPT2	566	P23786
PTEPNGEIVEYLILY	IGDCC4	871	Q8TDY8
YELEPSPLTQYILER	INTS6L	331	Q5JSJ4
ILLYGLLISYPQDDQ	CRPPA	406	A4D126
IPEGLPESLEYLYLQ	PODN	516	Q7Z5L7
LQYLTPLGEYQELLP	DCAF1	331	Q9Y4B6
EEDPYLVVNPNYLLE	MCM6	806	Q14566
AILPYYIGLLVPKND	KCND1	271	Q9NSA2
TPNYIAPEILRGEDY	PRKCI	416	P41743
YLSDLERLVTPGYVP	GNAT1	151	P11488
TPDYIAPEILQGLKY	PRKCD	511	Q05655
PDYIAPEILQELEYG	PRKCE	571	Q02156
IGDTLPPRQIYELYN	CFAP65	1311	Q6ZU64
QEYLELIGRPALPSY	MGAM	361	O43451
LTFLLEDPPLYGEIL	FREM2	981	Q5SZK8
LGPNSYYNLGPELEL	GDF3	131	Q9NR23
GYYEPTLLILFEPNQ	CPSF1	211	Q10570
YQPPDGGSLVEVYLL	PCSK9	171	Q8NBP7
YEISALEGGLPQLYP	GPR153	361	Q6NV75
GYDPPQLYLTQLREA	NOL6	1051	Q9H6R4
GQPLTPDEYLEYSLK	GBP3	191	Q9H0R5
LDLLVYGLYDPVNLE	MRO	91	Q9BYG7
LDELYPQGYPESVIQ	MSLN	356	Q13421
NDVVYLIRPDPLAYL	KCNT2	1096	Q6UVM3
LEDLLAFYGYEPTIP	MIER3	66	Q7Z3K6
PDRLPAGYEIVLYIS	PADI2	191	Q9Y2J8
LYEENGGIPRDLYLP	HECTD4	2301	Q9Y4D8
LLPDEEVVVYGIPYL	MMEL1	366	Q495T6
YQGDPELQPIRSYEI	SMPD4	726	Q9NXE4
PDELRYLPLNTALYE	PHF10	271	Q8WUB8
LSLELYPAPLESYDA	PRAMEF12	406	O95522
SYLPRQDLEGTPYLE	BRCA1	1551	P38398
DYLEIRDGPLYQDPL	CUBN	646	O60494
DDIIYRAQLELYPEP	FAM126A	261	Q9BYI3
LYELLILLPPETYEG	HEATR5A	671	Q86XA9
PLNAIDLLAILPYYV	KCNB1	261	Q14721
YILLSGNPPFYEEVE	CAMKV	211	Q8NCB2
IDENLPPESPYLYGL	DNAH17	4141	Q9UFH2
EVTYDPYLVLIPDVA	FCGBP	326	Q9Y6R7
LDPLEYAGLASVEPY	DHX57	161	Q6P158
YYLLEDQTVQPLPKG	MCRS1	261	Q96EZ8
IYYPLSKLDLIAIPD	ERAP2	316	Q6P179
PYPNYDRDILTIDIG	ECM1	401	Q16610
LIDADPYLKYLPSVI	CCNA2	341	P20248
VLLEPYALIIPGENY	DLEC1	756	Q9Y238
YDLDSLEQFPVPLGY	DNAH10	3806	Q8IVF4
LSLELYPAPLESYDT	PRAMEF8	406	Q5VWM4
LVPLPYGILIFVYDE	ATP4A	1001	P20648
EGEEPNYPLELLYCL	NLRP6	611	P59044
LEPILYNDILYTLPK	FOCAD	501	Q5VW36
TEELPDVPLYYTLDQ	TRMT1	436	Q9NXH9
IGIPLEDLDPYYSNK	SCN4A	76	P35499
LLIYYDDLLPSGVSD	IGLV1-36	66	A0A0B4J1U3
YLELPDLGQPYRSAV	NBPF11	721	Q86T75
YLELPDLGQPYRSAV	NBPF12	1236	Q5TAG4
PTILDIPNQLYYEGE	MOV10	736	Q9HCE1
YGYVPRTALLPLETE	PRAM1	636	Q96QH2
LLVPDNTFPLGYYLI	RNF167	161	Q9H6Y7
GIAPIFILYELDSPL	SLC46A3	276	Q7Z3Q1
LVSGQPLEEIITYYP	PTGES2	176	Q9H7Z7
YYLLSQEPEKALPIG	WDR17	1101	Q8IZU2
PELGEEDVYIGYLPL	ACSL3	316	O95573
LLYQYTPEELDLNTP	ANKFN1	156	Q8N957
LSLELYPAPLESYDT	PRAMEF7	406	Q5VXH5
FEIYNELLYDLLEPP	KIF20A	306	O95235
TIRLPYEEGELLEYL	SUPT20H	101	Q8NEM7
VYLIYGNDLGLPPVD	GPLD1	416	P80108
IDTYLDIPLVIRPYG	USP47	321	Q96K76
ALPLLYGTYVTILPE	XRN1	306	Q8IZH2
TDKILINVYDGPPLY	TPTE2	441	Q6XPS3
KALPILEELLRYYPD	TMTC3	721	Q6ZXV5
VTLNVLYGPDLPSIY	PSG5	231	Q15238
ALYPLLQDPAYLPEE	MARS1	151	P56192
YILADLLLGEPLIDY	TMEM38A	66	Q9H6F2
VLVAINPYEQLPIYG	MYO5A	106	Q9Y4I1
VLVAINPYEQLPIYG	MYO5B	106	Q9ULV0