Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	ATP6V1B2 DDX49 KIF27 ABCB5 ACSS1 NTPCR ABCC9 INO80 ABCA7 ABCA10 DDX23 MACF1 DNAH6 TAP2 ATP4A DYNC1H1 ACSL5	1.47e-06	614	140	17	GO:0140657
GeneOntologyMolecularFunction	ATP hydrolysis activity	DDX49 KIF27 ABCB5 NTPCR ABCC9 INO80 ABCA7 ABCA10 DDX23 MACF1 DNAH6 TAP2 ATP4A DYNC1H1	2.77e-06	441	140	14	GO:0016887
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ATP6V1B2 ABCB5 ABCC9 ABCA7 ABCA10 TAP2 ATP4A	1.18e-05	109	140	7	GO:0042626
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCB5 ABCC9 ABCA7 ABCA10 TAP2	2.35e-05	49	140	5	GO:0140359
GeneOntologyMolecularFunction	glucan 1,4-alpha-glucosidase activity	MGAM MGAM2	4.88e-05	2	140	2	GO:0004339
GeneOntologyMolecularFunction	isocitrate dehydrogenase (NADP+) activity	IDH1 IDH2	4.88e-05	2	140	2	GO:0004450
GeneOntologyMolecularFunction	dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity	ALG10B ALG10	4.88e-05	2	140	2	GO:0106073
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	DDX49 KIF27 ABCB5 NTPCR BMS1 ABCC9 INO80 ABCA7 ABCA10 TRIM23 DDX23 MACF1 DNAH6 TAP2 ATP4A DYNC1H1	1.09e-04	775	140	16	GO:0017111
GeneOntologyMolecularFunction	apolipoprotein receptor activity	ABCA7 LRP1	1.46e-04	3	140	2	GO:0030226
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ATP6V1B2 ABCB5 ABCC9 ABCA7 ABCA10 TAP2 ATP4A	2.64e-04	178	140	7	GO:0015399
GeneOntologyMolecularFunction	pyrophosphatase activity	DDX49 KIF27 ABCB5 NTPCR BMS1 ABCC9 INO80 ABCA7 ABCA10 TRIM23 DDX23 MACF1 DNAH6 TAP2 ATP4A DYNC1H1	2.69e-04	839	140	16	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	DDX49 KIF27 ABCB5 NTPCR BMS1 ABCC9 INO80 ABCA7 ABCA10 TRIM23 DDX23 MACF1 DNAH6 TAP2 ATP4A DYNC1H1	2.72e-04	840	140	16	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	DDX49 KIF27 ABCB5 NTPCR BMS1 ABCC9 INO80 ABCA7 ABCA10 TRIM23 DDX23 MACF1 DNAH6 TAP2 ATP4A DYNC1H1	2.72e-04	840	140	16	GO:0016818
GeneOntologyMolecularFunction	oxidized base lesion DNA N-glycosylase activity	SMUG1 MUTYH	2.90e-04	4	140	2	GO:0000702
GeneOntologyMolecularFunction	isocitrate dehydrogenase [NAD(P)+] activity	IDH1 IDH2	4.81e-04	5	140	2	GO:0004448
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	MGAM MGAM2	4.81e-04	5	140	2	GO:0004558
GeneOntologyMolecularFunction	alpha-glucosidase activity	MGAM MGAM2	1.00e-03	7	140	2	GO:0090599
GeneOntologyMolecularFunction	cell adhesion molecule binding	DSP DOCK9 CDH23 IDH1 PTPRB TENM4 CNTN5 TENM1 MACF1 DMD TNXB VSIG10L2	1.06e-03	599	140	12	GO:0050839
Domain	RIBOSOMAL_S4E	RPS4Y2 RPS4X RPS4Y1	4.21e-07	3	141	3	PS00528
Domain	Ribosomal_S4e_central_region	RPS4Y2 RPS4X RPS4Y1	4.21e-07	3	141	3	IPR013845
Domain	Ribosomal_S4e_N	RPS4Y2 RPS4X RPS4Y1	4.21e-07	3	141	3	IPR013843
Domain	Ribosomal_S4e_central	RPS4Y2 RPS4X RPS4Y1	4.21e-07	3	141	3	PD002667
Domain	40S_S4_C	RPS4Y2 RPS4X RPS4Y1	4.21e-07	3	141	3	PF16121
Domain	40S_S4_C	RPS4Y2 RPS4X RPS4Y1	4.21e-07	3	141	3	IPR032277
Domain	Ribosomal_S4e_N_CS	RPS4Y2 RPS4X RPS4Y1	4.21e-07	3	141	3	IPR018199
Domain	RS4NT	RPS4Y2 RPS4X RPS4Y1	4.21e-07	3	141	3	PF08071
Domain	Ribosomal_S4e	RPS4Y2 RPS4X RPS4Y1	4.21e-07	3	141	3	IPR000876
Domain	Ribosomal_S4e	RPS4Y2 RPS4X RPS4Y1	4.21e-07	3	141	3	PF00900
Domain	KOW	RPS4Y2 RPS4X RPS4Y1 SUPT5H	9.86e-07	11	141	4	IPR005824
Domain	KOW	RPS4Y2 RPS4X RPS4Y1 SUPT5H	9.86e-07	11	141	4	PF00467
Domain	S4	RPS4Y2 RPS4X RPS4Y1	4.17e-06	5	141	3	SM00363
Domain	S4	RPS4Y2 RPS4X RPS4Y1	4.17e-06	5	141	3	PS50889
Domain	S4_RNA-bd	RPS4Y2 RPS4X RPS4Y1	8.29e-06	6	141	3	IPR002942
Domain	AAA	ABCB5 NTPCR ABCC9 ABCA7 ABCA10 DNAH6 TAP2 DYNC1H1	1.37e-05	144	141	8	SM00382
Domain	AAA+_ATPase	ABCB5 NTPCR ABCC9 ABCA7 ABCA10 DNAH6 TAP2 DYNC1H1	1.37e-05	144	141	8	IPR003593
Domain	ABC_transporter_CS	ABCB5 ABCC9 ABCA7 ABCA10 TAP2	1.55e-05	42	141	5	IPR017871
Domain	ABC_tran	ABCB5 ABCC9 ABCA7 ABCA10 TAP2	3.01e-05	48	141	5	PF00005
Domain	ABC_TRANSPORTER_2	ABCB5 ABCC9 ABCA7 ABCA10 TAP2	3.01e-05	48	141	5	PS50893
Domain	ABC_TRANSPORTER_1	ABCB5 ABCC9 ABCA7 ABCA10 TAP2	3.33e-05	49	141	5	PS00211
Domain	ABC_transporter-like	ABCB5 ABCC9 ABCA7 ABCA10 TAP2	3.68e-05	50	141	5	IPR003439
Domain	Alg10	ALG10B ALG10	5.66e-05	2	141	2	IPR016900
Domain	Isocitrate_DH_NADP	IDH1 IDH2	5.66e-05	2	141	2	IPR004790
Domain	DIE2_ALG10	ALG10B ALG10	5.66e-05	2	141	2	PF04922
Domain	-	MPP2 ATP6V1B2 DDX49 ABCB5 NTPCR BMS1 ABCC9 INO80 ABCA7 ABCA10 TRIM23 DDX23 DNAH6 TAP2 DYNC1H1 NLRP13	1.64e-04	746	141	16	3.40.50.300
Domain	-	TENM4 TENM1 LRP1 LRP6	2.09e-04	39	141	4	2.120.10.30
Domain	P-loop_NTPase	MPP2 ATP6V1B2 DDX49 KIF27 ABCB5 NTPCR BMS1 ABCC9 INO80 ABCA7 ABCA10 TRIM23 DDX23 DNAH6 TAP2 DYNC1H1 NLRP13	2.27e-04	848	141	17	IPR027417
Domain	Tox-GHH_dom	TENM4 TENM1	3.36e-04	4	141	2	IPR028916
Domain	ELAD_HUD_SF	ELAVL2 ELAVL3	3.36e-04	4	141	2	IPR006548
Domain	Gal_mutarotase_N	MGAM MGAM2	3.36e-04	4	141	2	IPR031727
Domain	Tox-GHH	TENM4 TENM1	3.36e-04	4	141	2	PF15636
Domain	S4	RPS4X RPS4Y1	3.36e-04	4	141	2	PF01479
Domain	Ten_N	TENM4 TENM1	3.36e-04	4	141	2	IPR009471
Domain	Ten_N	TENM4 TENM1	3.36e-04	4	141	2	PF06484
Domain	TENEURIN_N	TENM4 TENM1	3.36e-04	4	141	2	PS51361
Domain	NtCtMGAM_N	MGAM MGAM2	3.36e-04	4	141	2	PF16863
Domain	6-blade_b-propeller_TolB-like	TENM4 TENM1 LRP1 LRP6	3.97e-04	46	141	4	IPR011042
Domain	EGF	FCGBP TENM4 CELSR2 CNTNAP2 TENM1 LRP1 LRP6 TNXB	4.20e-04	235	141	8	SM00181
Domain	WW	HECW1 SMURF1 DMD SMURF2	4.32e-04	47	141	4	PF00397
Domain	WW	HECW1 SMURF1 DMD SMURF2	4.68e-04	48	141	4	SM00456
Domain	Isocitrate/isopropylmalate_DH	IDH1 IDH2	5.58e-04	5	141	2	IPR001804
Domain	Iso_dh	IDH1 IDH2	5.58e-04	5	141	2	PF00180
Domain	YD	TENM4 TENM1	5.58e-04	5	141	2	IPR006530
Domain	IsoCit/isopropylmalate_DH_CS	IDH1 IDH2	5.58e-04	5	141	2	IPR019818
Domain	Iso_dh	IDH1 IDH2	5.58e-04	5	141	2	SM01329
Domain	IDH_IMDH	IDH1 IDH2	5.58e-04	5	141	2	PS00470
Domain	IsoPropMal-DH-like_dom	IDH1 IDH2	5.58e-04	5	141	2	IPR024084
Domain	-	IDH1 IDH2	5.58e-04	5	141	2	3.40.718.10
Domain	WW_DOMAIN_1	HECW1 SMURF1 DMD SMURF2	5.91e-04	51	141	4	PS01159
Domain	WW_DOMAIN_2	HECW1 SMURF1 DMD SMURF2	5.91e-04	51	141	4	PS50020
Domain	EGF-like_dom	FCGBP TENM4 CELSR2 CNTNAP2 TENM1 LRP1 LRP6 TNXB	6.15e-04	249	141	8	IPR000742
Domain	WW_dom	HECW1 SMURF1 DMD SMURF2	6.36e-04	52	141	4	IPR001202
Domain	ABC_membrane	ABCB5 ABCC9 TAP2	7.59e-04	24	141	3	PF00664
Domain	-	DSP MACF1	8.32e-04	6	141	2	3.90.1290.10
Domain	Glyco_hydro_31_AS	MGAM MGAM2	8.32e-04	6	141	2	IPR030458
Domain	HECT	HECW1 SMURF1 SMURF2	1.08e-03	27	141	3	PF00632
Domain	HECTc	HECW1 SMURF1 SMURF2	1.08e-03	27	141	3	SM00119
Domain	HECT_dom	HECW1 SMURF1 SMURF2	1.08e-03	27	141	3	IPR000569
Domain	HECT	HECW1 SMURF1 SMURF2	1.08e-03	27	141	3	PS50237
Domain	ARM-type_fold	TRPC4AP DOCK9 CUL9 WDFY4 EFR3A IFRD2 LRBA HEATR5B HEATR3	1.10e-03	339	141	9	IPR016024
Domain	Glyco_hydro_31	MGAM MGAM2	1.16e-03	7	141	2	IPR000322
Domain	KOW	RPS4Y2 SUPT5H	1.16e-03	7	141	2	SM00739
Domain	Plectin	DSP MACF1	1.16e-03	7	141	2	PF00681
Domain	Cullin_CS	CUL1 CUL9	1.16e-03	7	141	2	IPR016157
Domain	Glyco_hydro_31	MGAM MGAM2	1.16e-03	7	141	2	PF01055
Domain	Plectin_repeat	DSP MACF1	1.16e-03	7	141	2	IPR001101
Domain	GLYCOSYL_HYDROL_F31_1	MGAM MGAM2	1.16e-03	7	141	2	PS00129
Domain	PLEC	DSP MACF1	1.16e-03	7	141	2	SM00250
Domain	ABC_TM1F	ABCB5 ABCC9 TAP2	1.20e-03	28	141	3	PS50929
Domain	ABC1_TM_dom	ABCB5 ABCC9 TAP2	1.20e-03	28	141	3	IPR011527
Domain	Spectrin_repeat	DSP MACF1 DMD	1.33e-03	29	141	3	IPR002017
Domain	-	CUL9 WDFY4 EFR3A IFRD2 LRBA HEATR5B HEATR3	1.50e-03	222	141	7	1.25.10.10
Domain	Cullin_neddylation_domain	CUL1 CUL9	1.54e-03	8	141	2	IPR019559
Domain	PH-BEACH_dom	WDFY4 LRBA	1.54e-03	8	141	2	IPR023362
Domain	Cullin_Nedd8	CUL1 CUL9	1.54e-03	8	141	2	PF10557
Domain	Cullin_Nedd8	CUL1 CUL9	1.54e-03	8	141	2	SM00884
Domain	-	WDFY4 LRBA	1.54e-03	8	141	2	2.30.29.40
Domain	Trefoil	MGAM MGAM2	1.54e-03	8	141	2	PF00088
Domain	PH_BEACH	WDFY4 LRBA	1.54e-03	8	141	2	PS51783
Domain	SPEC	DSP MACF1 DMD	1.78e-03	32	141	3	SM00150
Domain	Spectrin/alpha-actinin	DSP MACF1 DMD	1.78e-03	32	141	3	IPR018159
Domain	BEACH	WDFY4 LRBA	1.97e-03	9	141	2	PS50197
Domain	Beach	WDFY4 LRBA	1.97e-03	9	141	2	PF02138
Domain	Cullin_homology	CUL1 CUL9	1.97e-03	9	141	2	IPR016158
Domain	-	WDFY4 LRBA	1.97e-03	9	141	2	1.10.1540.10
Domain	P_TREFOIL_2	MGAM MGAM2	1.97e-03	9	141	2	PS51448
Domain	Beach	WDFY4 LRBA	1.97e-03	9	141	2	SM01026
Domain	BEACH_dom	WDFY4 LRBA	1.97e-03	9	141	2	IPR000409
Domain	PD	MGAM MGAM2	1.97e-03	9	141	2	SM00018
Domain	EGF_3	TENM4 CELSR2 CNTNAP2 TENM1 LRP1 LRP6 TNXB	2.07e-03	235	141	7	PS50026
Domain	Cullin	CUL1 CUL9	2.45e-03	10	141	2	PF00888
Domain	Hud_Sxl_RNA	ELAVL2 ELAVL3	2.45e-03	10	141	2	IPR002343
Domain	CULLIN_2	CUL1 CUL9	2.45e-03	10	141	2	PS50069
Domain	Cullin_N	CUL1 CUL9	2.45e-03	10	141	2	IPR001373
Domain	CULLIN_1	CUL1 CUL9	2.45e-03	10	141	2	PS01256
Domain	EGF	CELSR2 CNTNAP2 LRP1 LRP6 TNXB	2.69e-03	126	141	5	PF00008
Domain	-	MGAM MGAM2	2.98e-03	11	141	2	4.10.110.10
Domain	EGF_1	TENM4 CELSR2 CNTNAP2 TENM1 LRP1 LRP6 TNXB	3.27e-03	255	141	7	PS00022
Domain	P_trefoil_dom	MGAM MGAM2	3.55e-03	12	141	2	IPR000519
Pathway	KEGG_ABC_TRANSPORTERS	ABCB5 ABCC9 ABCA7 ABCA10 TAP2	1.80e-05	44	105	5	M11911
Pubmed	Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome.	RPS4Y2 RPS4X RPS4Y1	6.66e-08	3	142	3	2124517
Pubmed	Expression level of Rps4 mRNA in 39,X mice and 40,XX mice.	RPS4Y2 RPS4X RPS4Y1	6.66e-08	3	142	3	8187552
Pubmed	Relationship between the monosomy X phenotype and Y-linked ribosomal protein S4 (Rps4) in several species of mammals: a molecular evolutionary analysis of Rps4 homologs.	RPS4Y2 RPS4X RPS4Y1	6.66e-08	3	142	3	8808278
Pubmed	Inactivation of the Rps4 gene on the mouse X chromosome.	RPS4Y2 RPS4X RPS4Y1	6.66e-08	3	142	3	1783379
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RPS4Y2 MPP2 ATP6V1B2 KRT19 DSP RPS4X RPS4Y1 AAK1 SMURF1 IDH2 PFKM PGM1 TENM4 SUGP2 SORCS2 SNX27 ELAVL3 MACF1 DMD DNAH6 CNOT1 DYNC1H1	8.88e-08	1431	142	22	37142655
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DDX49 DSP RPS4X BMS1 SMURF1 MRPL19 INO80 IDH2 GPC6 SUGP2 SUPT5H NAT10 DDX23 ELAVL2 ELAVL3 MACF1 CNOT1 TNXB DYNC1H1	9.77e-08	1082	142	19	38697112
Pubmed	Rps4 maps near the inactivation center on the mouse X chromosome.	RPS4Y2 RPS4X RPS4Y1 DMD	1.85e-07	13	142	4	1740345
Pubmed	XIST and the mapping of the X chromosome inactivation centre.	RPS4Y2 RPS4X RPS4Y1 DMD	1.85e-07	13	142	4	1772416
Pubmed	Structure and function of ribosomal protein S4 genes on the human and mouse sex chromosomes.	RPS4Y2 RPS4X RPS4Y1	2.66e-07	4	142	3	8139551
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	INCENP DSP RPS4X BMS1 CUL9 SUGP2 SUPT5H NAT10 DDX23 MACF1 FUBP3 CNOT1 PHIP DYNC1H1	5.20e-07	653	142	14	22586326
Pubmed	Use of a reverse transcriptase-polymerase chain reaction assay to analyze allele-specific expression in individual hippocampal neurons.	RPS4Y2 RPS4X RPS4Y1	6.62e-07	5	142	3	9562962
Pubmed	Maintenance of X inactivation of the Rps4, Zfx, and Ube1 genes in a mouse in vitro system.	RPS4Y2 RPS4X RPS4Y1	6.62e-07	5	142	3	7681608
Pubmed	Molecular background of oligodendroglioma: 1p/19q, IDH, TERT, CIC and FUBP1.	IDH1 IDH2 FUBP1	6.62e-07	5	142	3	26545048
Pubmed	SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.	CUL1 HECW1 SMURF1 SMURF2	9.84e-07	19	142	4	21572392
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	ATP6V1B2 DSP RPS4X OBSL1 AARS2 SUGP2 SUPT5H FUBP1 NAT10 DDX23 MACF1 HEATR5B SCIN FUBP3 CNOT1 PHIP DYNC1H1	1.05e-06	1024	142	17	24711643
Pubmed	Embryonic growth and the evolution of the mammalian Y chromosome. II. Suppression of selfish Y-linked growth factors may explain escape from X-inactivation and rapid evolution of Sry.	RPS4Y2 RPS4X RPS4Y1	2.30e-06	7	142	3	7928394
Pubmed	An evaluation of the inactive mouse X chromosome in somatic cell hybrids.	RPS4Y2 RPS4X RPS4Y1	2.30e-06	7	142	3	8460399
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	CUL1 DDX49 INCENP GNE DSP RPS4X BMS1 AAK1 PFKM SUGP2 FUBP1 TPP1 NAT10 SNX27 DDX23 MACF1 FUBP3 PHIP DYNC1H1	2.78e-06	1353	142	19	29467282
Pubmed	Physical mapping of 2000 kb of the mouse X chromosome in the vicinity of the Xist locus.	RPS4Y2 RPS4X RPS4Y1	3.68e-06	8	142	3	8468051
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	RPS4Y2 MPP2 HECW1 DSP RPS4X RPS4Y1 DOCK9 ATG2B AAK1 IDH2 TENM4 CELSR2 SUGP2 CNTNAP2 TENM1 MACF1 CNOT1	4.38e-06	1139	142	17	36417873
Pubmed	Cloning and localization of the murine Xpct gene: evidence for complex rearrangements during the evolution of the region around the Xist gene.	RPS4Y2 RPS4X RPS4Y1	5.50e-06	9	142	3	9545634
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	RPS4X NTPCR BMS1 LSM1 SUGP2 SUPT5H FUBP1 NAT10 DDX23 ELAVL2 MACF1 FUBP3 CNOT1 DYNC1H1	6.08e-06	807	142	14	22681889
Pubmed	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	ATP6V1B2 GPC6 CNTN5 CNTNAP2 DMD	6.64e-06	64	142	5	20889312
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK9 SMURF1 OBSL1 DDN CUL9 TENM4 SUGP2 SNX27 MACF1 DYNC1H1	7.27e-06	407	142	10	12693553
Pubmed	Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.	MGAM ACSS1 IDH1 IDH2 PFKM PGM1	7.73e-06	114	142	6	28245920
Pubmed	DYRK3 phosphorylates SNAPIN to regulate axonal retrograde transport and neurotransmitter release.	PGM1 DYNC1H1 DYRK3	7.83e-06	10	142	3	36585413
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	RPS4Y2 MPP2 ATP6V1B2 RPS4X RPS4Y1 ABCC9 PFKM TRIM23 ELAVL2 ELAVL3 ATP4A DYNC1H1	9.99e-06	621	142	12	22794259
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	CUL1 INCENP ACSS1 TMEM135 NTPCR ATG2B BMS1 OBSL1 PUSL1 MRPL19 IDH2 PFKM CRYZ AARS2 FUBP1 NAT10 ELAVL2 FUBP3 PHIP	1.16e-05	1496	142	19	32877691
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	LRFN1 DOCK9 NLRX1 CUL9 INO80 ABCA7 PLEKHH3 SCAP CELSR2 SUGP2 TRAPPC12 IFRD2 LTK LRBA SMURF2 DYNC1H1	1.24e-05	1105	142	16	35748872
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	TRPC4AP LRFN1 DSP NUP210L C1orf167 SCAP FUBP1 NAT10 DDX23 DMD VSIG10L2 DYNC1H1 ILKAP	1.41e-05	754	142	13	35906200
Pubmed	Metabolism unhinged: IDH mutations in cancer.	IDH1 IDH2	1.66e-05	2	142	2	21383741
Pubmed	IDH1 and IDH2 mutations in patients with acute myeloid leukemia: Suitable targets for minimal residual disease monitoring?	IDH1 IDH2	1.66e-05	2	142	2	30176240
Pubmed	Vorasidenib, a Dual Inhibitor of Mutant IDH1/2, in Recurrent or Progressive Glioma; Results of a First-in-Human Phase I Trial.	IDH1 IDH2	1.66e-05	2	142	2	34078652
Pubmed	IDH1/IDH2 mutations define the prognosis and molecular profiles of patients with gliomas: a meta-analysis.	IDH1 IDH2	1.66e-05	2	142	2	23894344
Pubmed	High incidence of IDH mutations in acute myeloid leukaemia with cuplike nuclei.	IDH1 IDH2	1.66e-05	2	142	2	21480859
Pubmed	Study of mutations in IDH1 and IDH2 genes in a sample of gliomas from Colombian population.	IDH1 IDH2	1.66e-05	2	142	2	29874711
Pubmed	Molecular profiling of cholangiocarcinoma shows potential for targeted therapy treatment decisions.	IDH1 IDH2	1.66e-05	2	142	2	23391413
Pubmed	Highly specific determination of IDH status using edited in vivo magnetic resonance spectroscopy.	IDH1 IDH2	1.66e-05	2	142	2	29126125
Pubmed	Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations.	IDH1 IDH2	1.66e-05	2	142	2	20142433
Pubmed	IDH1 and IDH2 mutations in gliomas.	IDH1 IDH2	1.66e-05	2	142	2	23532369
Pubmed	[IDH1/2 mutations in gliomas].	IDH1 IDH2	1.66e-05	2	142	2	22147457
Pubmed	The prognostic value of IDH mutations and MGMT promoter status in secondary high-grade gliomas.	IDH1 IDH2	1.66e-05	2	142	2	23015095
Pubmed	Absence of IDH mutation in colorectal cancers with microsatellite instability.	IDH1 IDH2	1.66e-05	2	142	2	26987944
Pubmed	Pyrosequencing of IDH1 and IDH2 mutations in brain tumors and non-neoplastic conditions.	IDH1 IDH2	1.66e-05	2	142	2	23111198
Pubmed	Insular primary glioblastomas with IDH mutations: Clinical and biological specificities.	IDH1 IDH2	1.66e-05	2	142	2	28116838
Pubmed	Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value.	IDH1 IDH2	1.66e-05	2	142	2	20538800
Pubmed	IDH mutations in older patients with diffuse astrocytic gliomas.	IDH1 IDH2	1.66e-05	2	142	2	33137656
Pubmed	Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups.	IDH1 IDH2	1.66e-05	2	142	2	25783747
Pubmed	Type and location of isocitrate dehydrogenase mutations influence clinical characteristics and disease outcome of acute myeloid leukemia.	IDH1 IDH2	1.66e-05	2	142	2	23039322
Pubmed	Characterisation of isocitrate dehydrogenase 1/isocitrate dehydrogenase 2 gene mutation and the d-2-hydroxyglutarate oncometabolite level in dedifferentiated chondrosarcoma.	IDH1 IDH2	1.66e-05	2	142	2	31609487
Pubmed	Contraction-Induced Loss of Plasmalemmal Electrophysiological Function Is Dependent on the Dystrophin Glycoprotein Complex.	SGCB DMD	1.66e-05	2	142	2	34764884
Pubmed	Association of Maximal Extent of Resection of Contrast-Enhanced and Non-Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma.	IDH1 IDH2	1.66e-05	2	142	2	32027343
Pubmed	Long-term survival in primary glioblastoma with versus without isocitrate dehydrogenase mutations.	IDH1 IDH2	1.66e-05	2	142	2	23918605
Pubmed	IDH2 Mutation Analysis in Undifferentiated and Poorly Differentiated Sinonasal Carcinomas for Diagnosis and Clinical Management.	IDH1 IDH2	1.66e-05	2	142	2	31876581
Pubmed	IDH1 and IDH2 mutation analysis in Chinese patients with acute myeloid leukemia and myelodysplastic syndrome.	IDH1 IDH2	1.66e-05	2	142	2	21997850
Pubmed	Significance of IDH mutations varies with tumor histology, grade, and genetics in Japanese glioma patients.	IDH1 IDH2	1.66e-05	2	142	2	22136423
Pubmed	Isocitrate dehydrogenase (IDH) status prediction in histopathology images of gliomas using deep learning.	IDH1 IDH2	1.66e-05	2	142	2	32382048
Pubmed	Estimation of the occurrence rates of IDH1 and IDH2 mutations in gliomas and the reconsideration of IDH-wildtype anaplastic astrocytomas: an institutional experience.	IDH1 IDH2	1.66e-05	2	142	2	34162262
Pubmed	The functions and regulation of Smurfs in cancers.	SMURF1 SMURF2	1.66e-05	2	142	2	31899247
Pubmed	Differential prognostic impact of IDH1 and IDH2 mutations in chronic myelomonocytic leukemia.	IDH1 IDH2	1.66e-05	2	142	2	35351982
Pubmed	Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles.	IDH1 IDH2	1.66e-05	2	142	2	28297679
Pubmed	Isocitrate dehydrogenase mutations in gliomas: mechanisms, biomarkers and therapeutic target.	IDH1 IDH2	1.66e-05	2	142	2	22002076
Pubmed	Adverse impact of IDH1 and IDH2 mutations in primary AML: experience of the Spanish CETLAM group.	IDH1 IDH2	1.66e-05	2	142	2	22520341
Pubmed	[IDH1- and IDH2-mutations in brain glial tumors - the new antioncogenic mechanism].	IDH1 IDH2	1.66e-05	2	142	2	29863707
Pubmed	Acute myeloid leukemia with isolated del(5q) is associated with IDH1/IDH2 mutations and better prognosis when compared to acute myeloid leukemia with complex karyotype including del(5q).	IDH1 IDH2	1.66e-05	2	142	2	31685963
Pubmed	IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours.	IDH1 IDH2	1.66e-05	2	142	2	21598255
Pubmed	Reprogramming of Isocitrate Dehydrogenases Expression and Activity by the Androgen Receptor in Prostate Cancer.	IDH1 IDH2	1.66e-05	2	142	2	31068457
Pubmed	A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation.	IDH1 IDH2	1.66e-05	2	142	2	22922872
Pubmed	IDH Mutations in AML Patients; A higher Association with Intermediate Risk Cytogenetics.	IDH1 IDH2	1.66e-05	2	142	2	32212799
Pubmed	IDH mutations occur frequently in Chinese glioma patients and predict longer survival but not response to concomitant chemoradiotherapy in anaplastic gliomas.	IDH1 IDH2	1.66e-05	2	142	2	21874255
Pubmed	IDH1 and IDH2 mutations in myelodysplastic syndromes and role in disease progression.	IDH1 IDH2	1.66e-05	2	142	2	26228814
Pubmed	Co-deletion of chromosome 1p/19q and IDH1/2 mutation in glioma subsets of brain tumors in Chinese patients.	IDH1 IDH2	1.66e-05	2	142	2	22427879
Pubmed	Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production.	IDH1 IDH2	1.66e-05	2	142	2	21996744
Pubmed	IDH mutation analysis in gliomas as a diagnostic and prognostic biomarker.	IDH1 IDH2	1.66e-05	2	142	2	23451940
Pubmed	Differential isocitrate dehydrogenase 1 and isocitrate dehydrogenase 2 mutation-related landscape in intrahepatic cholangiocarcinoma.	IDH1 IDH2	1.66e-05	2	142	2	38842680
Pubmed	A nonsense mutation of IDH1 in myelodysplastic syndromes and related disorders.	IDH1 IDH2	1.66e-05	2	142	2	20962861
Pubmed	Diagnostic utility of IDH1/2 mutations to distinguish dedifferentiated chondrosarcoma from undifferentiated pleomorphic sarcoma of bone.	IDH1 IDH2	1.66e-05	2	142	2	28552826
Pubmed	The oncometabolite D-2-hydroxyglutarate induced by mutant IDH1 or -2 blocks osteoblast differentiation in vitro and in vivo.	IDH1 IDH2	1.66e-05	2	142	2	26046462
Pubmed	Mutations in the isocitrate dehydrogenase genes IDH1 and IDH2 in tumors.	IDH1 IDH2	1.66e-05	2	142	2	23232569
Pubmed	Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia.	IDH1 IDH2	1.66e-05	2	142	2	23641016
Pubmed	Distinct IDH1/IDH2 mutation profiles in purely insular versus paralimbic WHO Grade II gliomas.	IDH1 IDH2	1.66e-05	2	142	2	23330999
Pubmed	IDH1/2 Mutations in Sinonasal Undifferentiated Carcinomas : Previously Undescribed IDH2 R172K and R140x Variants.	IDH1 IDH2	1.66e-05	2	142	2	35486703
Pubmed	Metabolism of glioma and IDH1/IDH2 mutations.	IDH1 IDH2	1.66e-05	2	142	2	21885076
Pubmed	IDH1/2 Mutations in Cancer Stem Cells and Their Implications for Differentiation Therapy.	IDH1 IDH2	1.66e-05	2	142	2	34967233
Pubmed	Histopathological malignant progression of grade II and III gliomas correlated with IDH1/2 mutation status.	IDH1 IDH2	1.66e-05	2	142	2	22790483
Pubmed	IDH1 and IDH2 mutations in lung adenocarcinomas: Evidences of subclonal evolution.	IDH1 IDH2	1.66e-05	2	142	2	32333643
Pubmed	IDH1/2 mutations in acute myeloid leukemia patients and risk of coronary artery disease and cardiac dysfunction-a retrospective propensity score analysis.	IDH1 IDH2	1.66e-05	2	142	2	32948843
Pubmed	Mutant IDH: a targetable driver of leukemic phenotypes linking metabolism, epigenetics and transcriptional regulation.	IDH1 IDH2	1.66e-05	2	142	2	27431380
Pubmed	Fibrosis and inflammation are greater in muscles of beta-sarcoglycan-null mouse than mdx mouse.	SGCB DMD	1.66e-05	2	142	2	24723230
Pubmed	Functional evaluation of isocitrate dehydrogenase 1 and 2 variants of unclear significance in chronic myeloid neoplasms.	IDH1 IDH2	1.66e-05	2	142	2	31706195
Pubmed	Investigation of Isocitrate Dehydrogenase 1 and 2 Mutations in Acute Leukemia Patients in Saudi Arabia.	IDH1 IDH2	1.66e-05	2	142	2	34946913
Pubmed	Mutations of isocitrate dehydrogenase 1 and 2 in intrahepatic cholangiocarcinoma.	IDH1 IDH2	1.66e-05	2	142	2	24569570
Pubmed	Isocitrate dehydrogenase 1/2 mutational analyses and 2-hydroxyglutarate measurements in Wilms tumors.	IDH1 IDH2	1.66e-05	2	142	2	21225914
Pubmed	Cancer-associated IDH mutations: biomarker and therapeutic opportunities.	IDH1 IDH2	1.66e-05	2	142	2	20972461
Pubmed	Molecular investigation of isocitrate dehydrogenase gene (IDH) mutations in gliomas: first report of IDH2 mutations in Indian patients.	IDH1 IDH2	1.66e-05	2	142	2	24460285
Pubmed	IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide.	IDH1 IDH2	1.66e-05	2	142	2	19933982
Pubmed	Detection of IDH1 and IDH2 Mutation in Formalin-fixed Paraffin-embedded Gliomas Using Allele-specific COLD-PCR and Probe Melting Curve Analysis.	IDH1 IDH2	1.66e-05	2	142	2	30299371
Pubmed	SMURF1 and SMURF2 in Progenitor Cells from Articular Cartilage and Meniscus during Late-Stage Osteoarthritis.	SMURF1 SMURF2	1.66e-05	2	142	2	33090007
Pubmed	2-hydroxyglutarate accumulation caused by IDH mutation is involved in the formation of malignant gliomas.	IDH1 IDH2	1.66e-05	2	142	2	20367200
Pubmed	IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.	IDH1 IDH2	1.66e-05	2	142	2	20368543
Interaction	KIF23 interactions	RPS4Y2 CUL1 KIF27 INCENP DSP RPS4X RPS4Y1 BMS1 OBSL1 MRPL19 IDH2 PFKM EFR3A SUGP2 NAT10 DDX23 ELAVL2 MACF1 DMD HEATR5B PHIP DYNC1H1 NLRP13	7.70e-07	1031	141	23	int:KIF23
Cytoband	19p12	DDX49 SUGP2 TMEM59L ZNF714	1.82e-04	90	142	4	19p12
Cytoband	12q13.12	TROAP DDN DDX23	2.26e-04	38	142	3	12q13.12
Cytoband	11q12.3	INCENP SLC22A6 TMEM223	2.26e-04	38	142	3	11q12.3
Cytoband	Ensembl 112 genes in cytogenetic band chr12q13	SMUG1 TROAP DDN PFKM MIP LRP1 DDX23	3.67e-04	423	142	7	chr12q13
GeneFamily	Alpha-1,2-glucosyltransferases	ALG10B ALG10	2.67e-05	2	94	2	448
GeneFamily	S ribosomal proteins	RPS4Y2 RPS4X RPS4Y1	7.25e-04	34	94	3	728
GeneFamily	EF-hand domain containing\|Plakins	DSP MACF1	7.34e-04	8	94	2	939
GeneFamily	Cullins	CUL1 CUL9	7.34e-04	8	94	2	1032
GeneFamily	WD repeat domain containing\|BEACH domain containing	WDFY4 LRBA	9.40e-04	9	94	2	1230
GeneFamily	ATP binding cassette subfamily B	ABCB5 TAP2	1.43e-03	11	94	2	806
GeneFamily	DNA glycosylases	SMUG1 MUTYH	1.43e-03	11	94	2	1024
GeneFamily	Low density lipoprotein receptors	LRP1 LRP6	2.01e-03	13	94	2	634
GeneFamily	ATP binding cassette subfamily A	ABCA7 ABCA10	2.34e-03	14	94	2	805
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCC9 GPC6 TENM4 CNTN5 SORCS2 LHFPL6 SLC12A7 DNAH6	1.14e-07	179	142	8	b35a7f8115c997c390201da01d7cb10b10769aec
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARRES2 ABCC9 CELSR2 GPR149 ELAVL2 SIGLEC1 SCIN	9.49e-07	163	142	7	1eec7f5e5fed05fa21d3f81db588f10605f08ea7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CDH23 GPC6 ABCA10 LRP1 LHFPL6 DMD TNXB	1.53e-06	175	142	7	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	wk_15-18-Epithelial-PNS-SST+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	HECW1 CNTN5 ELAVL2 ELAVL3 SYT4 LTK ATP4A	1.98e-06	182	142	7	a7e77aaaddabf78c7784f72b3431703fc5ee4a8c
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCC9 TENM4 CNTN5 SORCS2 LHFPL6 SLC12A7 DNAH6	2.13e-06	184	142	7	9cc5c588f7c6631b3fb8a522214a09ca32947e72
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CDH23 ABCC9 ABCA10 LRP1 LHFPL6 DMD TNXB	2.64e-06	190	142	7	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	droplet-Heart-nan-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARRES2 DSP OBSL1 GPC6 LRP1 LHFPL6 TNXB	2.64e-06	190	142	7	96a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 TMEM200A TENM4 CNTN5 CNTNAP2 ELAVL2 SYT4	2.92e-06	193	142	7	461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 TMEM200A TENM4 CNTN5 CNTNAP2 ELAVL2 SYT4	2.92e-06	193	142	7	0dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38\|World / Primary Cells by Cluster	BAZ2B RPS4Y1 FCGBP TENM4 CELSR2 ELAVL2 PHIP	3.24e-06	196	142	7	38da0751941adca650fe9b383d9f343153978eb5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC9 TMEM200A NRP2 LRP1 LHFPL6 DMD TNXB	3.24e-06	196	142	7	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn\|World / Primary Cells by Cluster	BAZ2B RPS4Y1 FCGBP TENM4 CELSR2 ELAVL2 PHIP	3.24e-06	196	142	7	721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC9 TMEM200A NRP2 LRP1 LHFPL6 DMD TNXB	3.24e-06	196	142	7	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MPP2 MGAM HECW1 TENM1 ELAVL2 TMEM223 DMD	3.46e-06	198	142	7	d1827e3707b929e3a3562989a0c11537d344e164
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Neuronal\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	NRP2 TMEM59L CNTNAP2 ELAVL2 LHFPL6 ELAVL3 SYT4	3.58e-06	199	142	7	f94307958cead25d38103fcbb35fa45011de1687
ToppCell	Striatum-Neuronal\|Striatum / BrainAtlas - Mouse McCarroll V32	ATP6V1B2 HECW1 AAK1 TMEM59L CNTNAP2 TENM1 SYT4	3.70e-06	200	142	7	c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCell	Neuronal-Excitatory-eB(RORB)-SEMA3E-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ABCC9 TENM4 CNTN5 SORCS2 LHFPL6 SLC12A7 DNAH6	3.70e-06	200	142	7	1a3d29a580d1b405a74869a1da3e818c581fc559
ToppCell	Neuronal-Excitatory-eB(RORB)-SEMA3E---L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ABCC9 TENM4 CNTN5 SORCS2 LHFPL6 SLC12A7 DNAH6	3.70e-06	200	142	7	6f9ed8fe9cda91185c3a1a675353e11b8fec6ef1
ToppCell	Neuronal-Excitatory-eB(RORB)-SEMA3E--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ABCC9 TENM4 CNTN5 SORCS2 LHFPL6 SLC12A7 DNAH6	3.70e-06	200	142	7	86705dfc05b3e1576543b93883c88fb55b742855
ToppCell	Neuronal-Excitatory-eB(RORB)-SEMA3E\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ABCC9 TENM4 CNTN5 SORCS2 LHFPL6 SLC12A7 DNAH6	3.70e-06	200	142	7	db194b4f524fd008b3c5b4b6014b436190a1b87a
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	NPR2 CUL9 ABCA10 EXD3 TPP1 DMD	9.44e-06	152	142	6	eb7ff36792c3c54ac88cfe976f84016b70b1a1d7
ToppCell	facs-Marrow-KLS-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARRES2 ABCC9 GPC6 EFR3A PTPRB SORCS2	1.02e-05	154	142	6	37765512dfae557b9f6eb30a29463b93682a4404
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_2\|367C / Donor, Lineage, Cell class and subclass (all cells)	MGAM TROAP FCGBP SUGP2 SIGLEC1 ZNF714	1.45e-05	164	142	6	0662cd9d21608efacc336e0a582859f3b9a4951d
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF596 C1orf167 GPC6 TENM4 SORCS2 LOXL4	1.45e-05	164	142	6	d167c7a987b9b35d1e7725c803df4f9cd5380e47
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	MGAM IDH1 WDFY4 NRP2 FCGBP SIGLEC1	1.78e-05	170	142	6	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MPP2 RARRES2 TMEM200A PLEKHH3 LHFPL6 DMD	2.38e-05	179	142	6	f5bb4d3a27d56698473219970e764084096cc582
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MPP2 RARRES2 TMEM200A PLEKHH3 LHFPL6 DMD	2.38e-05	179	142	6	fa03ec3cc0132f977b4cb28e7b23789732375183
ToppCell	droplet-Kidney-KIDNEY\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARRES2 IDH1 IDH2 METTL26 SLC22A6 CRYZ	2.54e-05	181	142	6	3a8c2bc0199b8fe2235ada14672bd31153d5a682
ToppCell	droplet-Lung-30m-Mesenchymal-myofibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MPP2 RARRES2 TMEM200A B9D1 LHFPL6 DMD	2.78e-05	184	142	6	55dde9c4eebac2a33788c1ff1d8fe312d150fad4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GPC6 ABCA10 LRP1 LHFPL6 DMD TNXB	2.78e-05	184	142	6	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	droplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MPP2 RARRES2 TMEM200A B9D1 LHFPL6 DMD	2.78e-05	184	142	6	7128a2be291544d3df3ed6c80f21ddda8437dcba
ToppCell	droplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MPP2 RARRES2 TMEM200A B9D1 LHFPL6 DMD	2.78e-05	184	142	6	d14238f7b0b55a4c8d7040bea854bd221a66ac30
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCC9 CNTN5 SORCS2 LHFPL6 SLC12A7 DNAH6	2.87e-05	185	142	6	a1b2525da018abe458908cab7268bd403ee98d92
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPR149 TMEM59L ELAVL2 ELAVL3 SYT4 LTK	2.96e-05	186	142	6	18fd311252299d6d30ddb32002ed069056108206
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RARRES2 NRP2 LRP1 LHFPL6 MACF1 TNXB	3.43e-05	191	142	6	44a9a6768084dafc641ad455b65862bfd4cc0cb9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC9 ABCA10 LRP1 LHFPL6 DMD TNXB	3.43e-05	191	142	6	a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCell	droplet-Heart-nan-24m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARRES2 GPC6 LRP1 LHFPL6 SCIN TNXB	3.43e-05	191	142	6	1f660ea2841324d13f63e01f1789e606c2843fc4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC9 ABCA10 LRP1 LHFPL6 DMD TNXB	3.43e-05	191	142	6	8f6d592edc32fdb901af30501d4360512334e8c2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC9 ABCA10 LRP1 LHFPL6 DMD TNXB	3.53e-05	192	142	6	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC9 ABCA10 LRP1 LHFPL6 DMD TNXB	3.53e-05	192	142	6	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	Entopeduncular-Neuronal\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	HECW1 AAK1 CNTNAP2 TENM1 ELAVL2 SYT4	3.53e-05	192	142	6	4c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	GPC6 ABCA10 TENM4 LRP1 LHFPL6 TNXB	3.53e-05	192	142	6	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC9 ABCA10 LRP1 LHFPL6 DMD TNXB	3.53e-05	192	142	6	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	Control-B_naive-4\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	NPR2 FCGBP CELSR2 NAT10 SCIN	3.53e-05	116	142	5	35d471c8dbf408d0be3837c428d9c2a73c805a6f
ToppCell	droplet-Heart-nan-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARRES2 GPC6 LRP1 LHFPL6 SCIN TNXB	3.64e-05	193	142	6	0ca0439dfdcb2361ca8d1015fb874a5b5c635d31
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARRES2 GPC6 LRP1 LHFPL6 SCIN TNXB	3.64e-05	193	142	6	0a665531d581d4e3941e29d3f95569da8f166447
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARRES2 GPC6 LRP1 LHFPL6 SCIN TNXB	3.64e-05	193	142	6	24ce1f37cca655415410d2403a52d1ebb3332280
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC9 ABCA10 LRP1 LHFPL6 DMD TNXB	3.74e-05	194	142	6	81713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC9 ABCA10 LRP1 LHFPL6 DMD TNXB	3.74e-05	194	142	6	c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCell	facs-Heart-RA-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARRES2 ABCC9 GPC6 LRP1 LHFPL6 TNXB	3.74e-05	194	142	6	c422aeddb4e949a22f731da675bdf91dee86ba61
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARRES2 GPC6 LRP1 LHFPL6 SCIN TNXB	3.74e-05	194	142	6	2d0cff9dc538a14518741e2a96d9d78442c81a72
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RARRES2 ABCC9 TMEM59L LRP1 LHFPL6 TNXB	3.74e-05	194	142	6	02b8102be9414d6964cd71019613edff6d88b893
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RARRES2 ABCC9 TMEM59L LRP1 LHFPL6 TNXB	3.74e-05	194	142	6	29f83cdd63314fff41258937d70b881a5503bfcc
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC9 ABCA10 LRP1 LHFPL6 DMD TNXB	3.74e-05	194	142	6	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	RARRES2 INCENP TROAP ABCC9 GPC6 LHFPL6	3.74e-05	194	142	6	d840c1949c328779426c9172e02da09e968f0567
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RARRES2 ABCC9 TMEM59L LRP1 LHFPL6 TNXB	3.74e-05	194	142	6	d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC9 ABCA10 LRP1 LHFPL6 DMD TNXB	3.74e-05	194	142	6	627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RARRES2 GPC6 ABCA10 LRP1 MACF1 TNXB	3.85e-05	195	142	6	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RARRES2 GPC6 ABCA10 LRP1 MACF1 TNXB	3.85e-05	195	142	6	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC9 ABCA10 LRP1 LHFPL6 DMD TNXB	3.85e-05	195	142	6	3c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARRES2 ABCC9 GPC6 LRP1 LHFPL6 DMD	3.96e-05	196	142	6	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARRES2 ABCC9 GPC6 LRP1 LHFPL6 DMD	3.96e-05	196	142	6	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RARRES2 GPC6 ABCA10 LRP1 MACF1 TNXB	3.96e-05	196	142	6	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HECW1 TMEM59L CNTNAP2 ELAVL3 SYT4 LTK	4.08e-05	197	142	6	27c044833e471a312a572e0b1c83e4bc8a36e896
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC9 ABCA10 LRP1 LHFPL6 DMD TNXB	4.08e-05	197	142	6	ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RARRES2 OBSL1 ABCC9 GPC6 ABCA10 LHFPL6	4.08e-05	197	142	6	3bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC9 ABCA10 LRP1 LHFPL6 DMD TNXB	4.08e-05	197	142	6	37f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCC9 GPC6 ABCA10 LRP1 LHFPL6 TNXB	4.08e-05	197	142	6	71786e9432e2d649f5d86f639abb25e7102deb67
ToppCell	wk_08-11-Epithelial-Airway_epithelial_progenitor-epi-airway_progenitor_early\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	KRT19 DSP PCDH17 DMKN LRBA DMD	4.08e-05	197	142	6	4ae08ccb6f1da626c4f0fb0140a2811cb6e31ba1
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RARRES2 OBSL1 ABCC9 GPC6 ABCA10 LHFPL6	4.08e-05	197	142	6	17344464fdcc5ba0c03959696b97c195f11e644c
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RARRES2 OBSL1 ABCC9 GPC6 ABCA10 LHFPL6	4.08e-05	197	142	6	5b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RARRES2 GPC6 CNTNAP2 LRP1 LHFPL6 MACF1	4.19e-05	198	142	6	17dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Neuronal-PNs\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	NRP2 TMEM59L CNTNAP2 ELAVL2 ELAVL3 SYT4	4.31e-05	199	142	6	c8aaf6ebd1cb6f6e59fdffeb81f9a3c921cc592a
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MPP2 PCDH17 CELSR2 SORCS2 LRP6 ELAVL3	4.31e-05	199	142	6	5d2e85e40b6b52b1809e680b952913d77215b3d0
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MPP2 PCDH17 CELSR2 SORCS2 LRP6 ELAVL3	4.31e-05	199	142	6	9dd4b17fb8c70ab9e126b23b72600463f3db832d
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	RARRES2 BAZ2B LRP1 LHFPL6 DMD TNXB	4.31e-05	199	142	6	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MPP2 PCDH17 CELSR2 SORCS2 LRP6 ELAVL3	4.31e-05	199	142	6	6fb5f931e6217142de38c1fffc011e63bda4772b
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RARRES2 GPC6 DMKN LRP1 LOXL4 LHFPL6	4.31e-05	199	142	6	e78f661b40da34768469549b6e755d330be6bbd8
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MPP2 PCDH17 CELSR2 SORCS2 LRP6 ELAVL3	4.31e-05	199	142	6	1bb5797e8e0552bf9b44bf4c958d1aa6dbe6c756
ToppCell	(5)_Fibroblast-D\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	RARRES2 GPC6 ABCA10 LRP1 LHFPL6 TNXB	4.31e-05	199	142	6	3f415620ad8b8d8c6871e1353e13f87b281fcc0e
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RARRES2 GPC6 ABCA10 LRP1 LHFPL6 TNXB	4.43e-05	200	142	6	17ffdbc13332bd3ed1d54abcd7af20267dd4b234
ToppCell	367C-Fibroblasts-Fibroblast-E-\|367C / Donor, Lineage, Cell class and subclass (all cells)	RARRES2 ABCC9 ABCA10 LRP1 LHFPL6 TNXB	4.43e-05	200	142	6	57b9d6aa2265ab178a5886f36ecc66115bd382a8
ToppCell	wk_20-22-Mesenchymal-Fibroblast-intermediate_fibro\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	RARRES2 GPC6 ABCA10 CNTNAP2 LRP1 LHFPL6	4.43e-05	200	142	6	d769723f8fcb37d9b86589e0c41c1d7f16393cfe
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RARRES2 GPC6 ABCA10 LRP1 LHFPL6 TNXB	4.43e-05	200	142	6	2e4ab7fbd94d3d865ef6188d3b4916d2bf1b8d89
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RARRES2 GPC6 ABCA10 LRP1 LHFPL6 TNXB	4.43e-05	200	142	6	665df8391d2ebcfc6536318612f4992852b5e2b8
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	RARRES2 BAZ2B LRP1 LHFPL6 DMD TNXB	4.43e-05	200	142	6	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Macroglial-Astrocyte\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	ACSS1 GPC6 CRYZ SORCS2 LHFPL6 DYRK3	4.43e-05	200	142	6	7c66953ff6d8f16f4decd23c85232990d2d8c6c4
ToppCell	(5)_Fibroblast-E\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	RARRES2 ABCC9 ABCA10 LRP1 LHFPL6 TNXB	4.43e-05	200	142	6	75e5ecb05e965e24d569aa2ef5cdf740b1528c06
ToppCell	wk_15-18-Mesenchymal-Fibroblast-intermediate_fibro\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	RARRES2 GPC6 ABCA10 CNTNAP2 LRP1 LHFPL6	4.43e-05	200	142	6	6461d25fd8fb52921b188f083fbe808535d3130b
ToppCell	367C-Fibroblasts-Fibroblast-E\|367C / Donor, Lineage, Cell class and subclass (all cells)	RARRES2 ABCC9 ABCA10 LRP1 LHFPL6 TNXB	4.43e-05	200	142	6	ddfbc004e7bd2fd3f11f046ed8fc049277160547
ToppCell	distal-2-Epithelial-Basal\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RARRES2 KRT19 GPC6 DMKN TMEM59L LOXL4	4.43e-05	200	142	6	9beb128841c50241aa819261f21bf66f881ea125
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2\|Control_saline / Treatment groups by lineage, cell group, cell type	ABCC9 PLEKHH3 LRP1 LRP6 LHFPL6 ELAVL3	4.43e-05	200	142	6	bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1-Excitatory_Neuron.Slc17a7.Fibcd1-Fos_(CA1_Principal_cells)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NUP210L ABCB5 AIRE TCFL5	4.90e-05	63	142	4	22ab24281a42b60e79a6d35e25f42e7f20cb04b9
ToppCell	droplet-Liver-Npc-21m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEKHH3 PRELID2 LOXL4 TNXB	7.84e-05	71	142	4	cf4c8715c2bd77fc86e45cc01bcc7aa6044e091d
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DDN KCNG3 LTK TCFL5 DYRK3	9.55e-05	143	142	5	5fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KCNG3 TMEM200A EFR3A SORCS2 DNAH6	9.87e-05	144	142	5	08005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell	mild_COVID-19_(asymptomatic)-NK_CD56bright\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	HECW1 B3GALNT2 CELSR2 DMKN DNAH6	1.23e-04	151	142	5	2470162f4b56bc505db166a6eb0fa54847759df8
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-Like-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MPP2 INCENP AIRE KCNG3 SIGLEC1	1.23e-04	151	142	5	c06a54afe918b14f885d6a85fbcf81e80f33afae
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NPR2 CUL9 EXD3 TPP1 DMD	1.27e-04	152	142	5	6d02b50e9e9ecf820f84a79e46d153a4840a1cfe
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF596 B3GALNT2 OBSL1 PCDH17 CNTNAP2	1.39e-04	155	142	5	d10cf5e922dbd3ca46660404da5aca43f181fc19
Disease	hepatocellular clear cell carcinoma (is_implicated_in)	IDH1 IDH2	2.17e-05	2	138	2	DOID:5016 (is_implicated_in)
Disease	Chondroma	IDH1 IDH2	2.17e-05	2	138	2	C0936248
Disease	Enchondroma	IDH1 IDH2	2.17e-05	2	138	2	C1704356
Disease	Long Qt Syndrome 2	ALG10B ALG10	6.49e-05	3	138	2	C3150943
Disease	Maffucci Syndrome	IDH1 IDH2	6.49e-05	3	138	2	C0024454
Disease	Enchondromatosis	IDH1 IDH2	1.29e-04	4	138	2	C0014084
Disease	Hemangioma, Intramuscular	IDH1 IDH2	1.29e-04	4	138	2	C0205789
Disease	Histiocytoid hemangioma	IDH1 IDH2	1.29e-04	4	138	2	C0205788
Disease	Chorioangioma	IDH1 IDH2	1.29e-04	4	138	2	C0677608
Disease	Angioma	IDH1 IDH2	1.29e-04	4	138	2	C1959588
Disease	Hemangioma	IDH1 IDH2	1.29e-04	4	138	2	C0018916
Disease	Headache	GPR149 LRP1 SNX27 MACF1	2.34e-04	64	138	4	HP_0002315
Disease	Biliary Tract Neoplasm	IDH1 IDH2	3.22e-04	6	138	2	C0005426
Disease	nonsyndromic deafness (implicated_via_orthology)	ALG10B ALG10	3.22e-04	6	138	2	DOID:0050563 (implicated_via_orthology)
Disease	bitter alcoholic beverage consumption measurement	DTD1 MGAM ACSS1 GPC6 CNTNAP2	4.14e-04	133	138	5	EFO_0010092
Disease	Childhood Oligodendroglioma	IDH1 IDH2	4.49e-04	7	138	2	C0280475
Disease	Adult Oligodendroglioma	IDH1 IDH2	4.49e-04	7	138	2	C0279070
Disease	Oligodendroblastoma	IDH1 IDH2	4.49e-04	7	138	2	C0344461
Disease	Mixed Oligodendroglioma-Astrocytoma	IDH1 IDH2	4.49e-04	7	138	2	C0280793
Disease	Mixed Oligodendroglioma-Ependymoma	IDH1 IDH2	4.49e-04	7	138	2	C0751395
Disease	Well Differentiated Oligodendroglioma	IDH1 IDH2	4.49e-04	7	138	2	C0751396
Disease	Colorectal Carcinoma	ABCB5 IDH1 ABCA10 PGM1 DMKN TENM1 LRP1 DMD PHIP MUTYH ACSL5	4.79e-04	702	138	11	C0009402
Disease	facial height measurement	GPC6 PCDH17 CNTN5 SCIN TAP2	5.58e-04	142	138	5	EFO_0007856
Disease	oligodendroglioma	IDH1 IDH2	5.97e-04	8	138	2	C0028945
Disease	Anaplastic Oligodendroglioma	IDH1 IDH2	5.97e-04	8	138	2	C0334590
Disease	lung squamous cell carcinoma (is_marker_for)	IDH1 IDH2 FUBP1	6.38e-04	36	138	3	DOID:3907 (is_marker_for)
Disease	lung adenocarcinoma (is_marker_for)	IDH1 IDH2 PTPRB FUBP1	6.92e-04	85	138	4	DOID:3910 (is_marker_for)
Disease	glucose metabolism decline measurement, cingulate cortex measurement	CDH23 VPS53	7.65e-04	9	138	2	EFO_0007738, EFO_0009392
Disease	dilated cardiomyopathy (is_implicated_in)	DSP ABCC9 DMD	1.08e-03	43	138	3	DOID:12930 (is_implicated_in)
Disease	diet measurement	DTD1 MPP2 MGAM NUP210L ACSS1 PCDH17 TENM4 CELSR2 CNTN5 MIP SYT4 CNOT1 ZNF714	1.32e-03	1049	138	13	EFO_0008111
Disease	amino acid measurement	MPP2 ZNF596 SMURF1 NRP2 PTPRB TENM4 CNTN5 ELAVL2 LRBA MGAM2	1.36e-03	678	138	10	EFO_0005134
Disease	complement C1q tumor necrosis factor-related protein 1 measurement	CDH23 CELSR2	1.39e-03	12	138	2	EFO_0801493
Disease	Hematologic Neoplasms	IDH1 IDH2	1.39e-03	12	138	2	C0376545
Disease	granulins measurement	CDH23 CELSR2	1.39e-03	12	138	2	EFO_0008141
Disease	major depressive episode	BAZ2B TENM4 CNTN5	1.40e-03	47	138	3	EFO_0007634
Disease	Cardiomyopathy, Dilated	SGCB ABCC9 DMD	1.48e-03	48	138	3	C0007193
Disease	mental or behavioural disorder	ATP6V1B2 GPC6 CNTN5 CNTNAP2 DMD	1.57e-03	179	138	5	EFO_0000677
Disease	Modic type vertebral endplate changes	MPP2 SCIN	1.64e-03	13	138	2	HP_0030775
Disease	alcohol dependence	MPP2 ALG10B TRAPPC12 CNTN5 ALG10	1.73e-03	183	138	5	MONDO_0007079
Disease	Glioblastoma Multiforme	CDC42BPG TMEM135 IDH1 IDH2	1.86e-03	111	138	4	C1621958
Disease	idiopathic osteonecrosis of the femoral head	PI4K2B KLHL20 SORCS2	1.87e-03	52	138	3	EFO_1001930
Disease	apolipoprotein A 1 measurement	MGAM CELSR2 GPR149 DHRS9 CES3 LRP1 MACF1 SYT4 CNOT1 VPS53 PHIP	2.18e-03	848	138	11	EFO_0004614
Disease	Down syndrome (implicated_via_orthology)	DYRK1B DYRK3	2.19e-03	15	138	2	DOID:14250 (implicated_via_orthology)
Disease	developmental dysplasia of the hip	LOXL4 VPS53	2.50e-03	16	138	2	EFO_1000648
Disease	Intrahepatic cholestasis of pregnancy	DHRS9 ATP4A	2.50e-03	16	138	2	EFO_0009048
Disease	migraine without aura, susceptibility to, 4	MPP2 LRP1	2.50e-03	16	138	2	MONDO_0011847
Disease	Glycogen storage disease	PFKM PGM1	2.82e-03	17	138	2	cv:C0017919
Disease	IGF-1 measurement, IGFBP-3 measurement	CELSR2 SORCS2	2.82e-03	17	138	2	EFO_0004626, EFO_0004627
Disease	sphingosine 1-phosphate measurement	SORCS2 DMD	3.16e-03	18	138	2	EFO_0800185
Disease	tea consumption measurement	MGAM CUL9 PLEKHH3 AARS2	3.21e-03	129	138	4	EFO_0010091
Disease	Cardiomyopathies	DSP SGCB ABCC9 DMD	3.30e-03	130	138	4	C0878544
Disease	fish consumption measurement	MPP2 TENM4 CNOT1	3.39e-03	64	138	3	EFO_0010139
Disease	Dyschondroplasias	IDH1 IDH2	3.52e-03	19	138	2	C0013366
Disease	hydrocephalus (implicated_via_orthology)	KIF27 CELSR2	3.52e-03	19	138	2	DOID:10908 (implicated_via_orthology)
Disease	response to methotrexate, neurotoxicity	GPC6 MACF1	3.52e-03	19	138	2	EFO_0011057, GO_0031427
Disease	Global developmental delay	TRAPPC12 SNX27 CNOT1 VPS53	3.58e-03	133	138	4	C0557874
Disease	Seizures	SGSH IDH2 NRP2 SNX27 MACF1	3.68e-03	218	138	5	C0036572
Disease	blood aluminium measurement	BAZ2B EFR3A	3.90e-03	20	138	2	EFO_0007575
Disease	susceptibility to mononucleosis measurement	CUL1 SYT4 DMD	4.19e-03	69	138	3	EFO_0008403

Protein segments in the cluster

Peptide	Gene	Start	Entry
IVESLGFQGGRLQRV	TMEM59L	191	Q9UK28
VITFNQGLRGGRVVE	ACSS1	216	Q9NUB1
SVQSAVRGGVQRAIL	C1orf167	1171	Q5SNV9
GVVVLQGSRASVRQQ	ABCA10	1261	Q8WWZ4
GRVFGIGRQQVTVDE	AAK1	36	Q2M2I8
DIAQIQGATGSRIGV	ABCB5	801	Q2M3G0
ETRIRNFGGRLQGEV	BAZ2B	756	Q9UIF8
ILVDQVTGVSRGVGF	ELAVL3	156	Q14576
GERGINLSGGQRQRI	ABCC9	806	O60706
AFVVVNGGIVIGDRS	ALG10B	266	Q5I7T1
TIQEGGTREDGLRIV	NPR2	351	P20594
TRQADGVLLQAITRG	CELSR2	1646	Q9HCU4
GIGQRQTVVRTLNAT	DMD	2151	P11532
QGRAEGSEVAVVQRR	DDN	581	O94850
FEGAVIRTVSGIRGQ	BMS1	1056	Q14692
VGGGTAVVQVRATDR	CDH23	1541	Q9H251
VTGVIRVGNATIDRE	CDH23	2121	Q9H251
GTRRLQEVLGVQTGG	DYRK1B	371	Q9Y463
RTEIRIAGIRGIQGV	EFR3A	161	Q14156
SRGVTGAVGEVLRQI	ATG2B	2021	Q96BY7
VARERERVVQGATQG	ABCA7	1776	Q8IZY2
GARGAVEGILIQQVF	AIRE	201	O43918
TRSAVSVREGQGVVL	CNTN5	201	O94779
ERRNGQLGSVALAVG	MIP	151	P30301
QRQEATLVVGGDGRF	PGM1	51	P36871
RIAAANGIGRLVIGQ	PGM1	76	P36871
AGTVIGNIGRDARLQ	PCDH17	31	O14917
GVGVAELTEAQRRGL	RARRES2	16	Q99969
GRVIVVGSRGTIEIN	CRYZ	241	Q08257
SSTQRQIDIGGGVVV	INO80	421	Q9ULG1
VIGRGAFGEVTVVRQ	CDC42BPG	76	Q6DT37
GENSQLQRAGVTLRV	KCNG3	276	Q8TAE7
GARQVLRVQGARSGD	OBSL1	1321	O75147
VSGGISSRQVVVEGR	PTPRB	626	P23467
EISTLRGQVGGQVSV	KRT19	221	P08727
VRLRSGAQVGEGRVE	LOXL4	311	Q96JB6
ATVVGENGSVLRRVT	INCENP	111	Q9NQS7
VQEVTGQRGVIITRS	MGAM2	1451	Q2M2H8
IGRGGEQISRIQQES	FUBP1	116	Q96AE4
GADETVQGQGSRRLI	HECW1	191	Q76N89
REDVVTNGIGRVEGI	LRP1	1956	Q07954
ITRQAGGRALVVEGQ	LRFN1	301	Q9P244
GGRALVVEGQAVSLR	LRFN1	306	Q9P244
SRGVVVAGQSQAGAR	ATXN1L	46	P0C7T5
AVQEVTGQRGVVITR	MGAM	1496	O43451
VEVGIVAIRGLFSGR	FGF3	81	P11487
RGIFVVRGENVVLLG	LSM1	61	O15116
VVTVGAAGQLRGVQL	LTK	96	P29376
RLSSQIQVVGNVGRL	KIF27	1336	Q86VH2
NTRVIALGVGVFLRG	OR51B2	136	Q9Y5P1
NAAVRAVVRVGIFTG	PFKM	31	P08237
NAAVRSTVRIGLIQG	PFKM	416	P08237
FIIGRGGEQISRIQA	FUBP3	91	Q96I24
VIIQGARGGDSITAV	NRP2	501	O60462
QATGGRGVALQVVRE	NRP2	721	O60462
TGGDRGVVVVRQVSD	LRBA	2796	P50851
NVINVTRLDGRSVGV	LRP6	1036	O75581
VRQGGRRIGFDVVTL	NTPCR	41	Q9BSD7
GVTFRVEGGELVIAR	MPP2	176	Q14168
TLVLIGAQGVGRRSL	MPP2	376	Q14168
GRRVQTVVLYGTVGT	NLRX1	156	Q86UT6
GIRTVAVIGGISRED	DDX23	496	Q9BUQ8
DLISRTVGRVAGGIQ	LHFPL6	111	Q9Y693
NGVAERQRSLFVVVG	NAT10	16	Q9H0A0
RQLQTGGIIDTVTGQ	MACF1	1811	Q9UPN3
AIVSIGLTIRNRGLG	OXER1	271	Q8TDS5
QTASRRSGQVLGVVL	GPR149	141	Q86SP6
GVRTKQIGDRVIQGC	OR52R1	296	Q8NGF1
CVIVERSQGGSQGRI	PI4K2B	446	Q8TCG2
QRVTRASVTVGGEQI	DTD1	6	Q8TEA8
IRQERGNALLVGVGG	DNAH6	2436	Q9C0G6
SNVGVRVNVVSILGI	HEATR3	551	Q7Z4Q2
NGTIRNILGGTVFRE	IDH1	96	O75874
NGTIRNILGGTVFRE	IDH2	136	P48735
GGSVNREVRVGVTQA	HEATR5B	296	Q9P2D3
FVQGLTVGREVANRV	GPC6	221	Q9Y625
TSRRSGVGLAVVNGQ	KLHL20	541	Q9Y2M5
LIADVVGIGGTRFQQ	DOCK9	1531	Q9BZ29
INLGTRQIGRETGEN	GNE	316	Q9Y223
LGQGTREAVGTGVRQ	DMKN	71	Q6E0U4
GNGRVSVTRVITVQV	FCGBP	1301	Q9Y6R7
RNGETINTRLISGVV	CUL1	191	Q13616
VTVNDGGGVLRVITA	B3GALNT2	241	Q8NCR0
GIERGIVDSITGQRL	DSP	2636	P15924
GNVRDGRVLGVLEVS	ILKAP	276	Q9H0C8
QDSLGGRVRVIVTGA	ACSL5	406	Q9ULC5
GGTGTCVRVTVQARV	C20orf27	126	Q9GZN8
ILVDQVTGISRGVGF	ELAVL2	156	Q12926
TDTVAIREQGNGRLV	MARF1	921	Q9Y4F3
SGQVSAQRTGRRLVG	IFRD2	31	Q12894
VQQRNLGVSGRIFTI	DYNC1H1	706	Q14204
CQQGGIDTRVRGVEV	CUL9	1281	Q8IWT3
VGRTARAGRQGQAIT	DDX49	336	Q9Y6V7
GVNRNSAIIGGVIAV	CNTNAP2	1256	Q9UHC6
VDTTLGRVRGRQVGV	CES3	36	Q6UWW8
AQGEGREVTRVRSQG	B9D1	151	Q9UPM9
QGRVINVSSVGGRLA	DHRS9	156	Q9BPW9
NRVLLVRGGGREVIT	SLC12A7	1066	Q9Y666
QGNLIVVGRSSGRLE	SCAP	976	Q12770
GGVGRFQQIQVTLVV	SLC22A6	11	Q4U2R8
LEGTVQGLVVNTGDR	ATP4A	261	P20648
QGLVVNTGDRTIIGR	ATP4A	266	P20648
TQADGRVVLVGGRSR	DYRK3	456	O43781
VNRRGQVTGKIVGTA	NUP210L	1126	Q5VU65
QRGVRVLEVASGSGQ	METTL26	26	Q96S19
NGVAAVRGTQRAVGV	PUSL1	26	Q8N0Z8
RGSRNEVIGQLVLGA	SYT4	381	Q9H2B2
ERAGRVEGRNGSITQ	ATP6V1B2	336	P21281
QRGAQERALAGGTLV	PLEKHH3	451	Q7Z736
LRQGQLTGRGLVRAV	TRPC4AP	41	Q8TEL6
ETQVIRNEGGVVVRF	TMEM200A	101	Q86VY9
DRSLGGQAVQIRVSQ	SCIN	461	Q9Y6U3
RGLQVSIQGEAVAVR	SORCS2	781	Q96PQ0
GANLGRVGVITNRER	RPS4Y1	186	P22090
GANLGRVGVITNRER	RPS4Y2	186	Q8TD47
ARAGQVVREAVGGLQ	TAP2	326	Q03519
VVREAVGGLQTVRSF	TAP2	331	Q03519
VLIGNTGGRRILENG	TENM1	2586	Q9UKZ4
TGGRRILENGVNVTV	TENM1	2591	Q9UKZ4
GQATGVVDGNVARVL	MUTYH	226	Q9UIF7
GANLGRIGVITNRER	RPS4X	186	P62701
QVVGQTGVIRSVTGG	SUPT5H	996	O00267
TVGGRRNENLVITGN	SGCB	126	Q16585
ENGSVLQVGRNITRI	SGSH	141	P51688
RTGAVGDLVIIGDRQ	AARS2	756	Q5JTZ9
GQIVVSLQTRDRIGT	SMURF1	131	Q9HCE7
AFVVVNGGIVIGDRS	ALG10	266	Q5BKT4
GVREVTAAQVARVLG	CNOT1	281	A5YKK6
GATFILRNVIEGQGV	MRPL19	146	P49406
QIVVSLQSRDRIGTG	SMURF2	131	Q9HAU4
LQSRDRIGTGGQVVD	SMURF2	136	Q9HAU4
VRSVVLRAGGQQVTL	TMEM223	121	A0PJW6
RGLGEQIARSGVQDQ	ZNF714	516	Q96N38
STQRISLLQGREVGI	ZNF596	66	Q8TC21
NVGLRRSGQIEGVRQ	PHIP	686	Q8WWQ0
TRGVLRAVATQQRGA	TRAPPC12	316	Q8WVT3
RAAQTGQVDGELIRG	SOGA1	46	O94964
SVLRGGSQVQARGRA	SUGP2	201	Q8IX01
VRVRGEESEVTVGGL	TNXB	2996	P22105
TIGAVAVGQLGVRVF	WDFY4	1346	Q6ZS81
GVARGTITTLRNGEV	TMEM135	141	Q86UB9
VLVRGSQGGTTQRVQ	TROAP	151	Q12815
TEFIQRGRISITGVG	PRELID2	136	Q8N945
GGRRTLENGVNVTVS	TENM4	2636	Q6N022
NVRGQVSEGGQLRSI	SNX27	56	Q96L92
TIGRLQVEGARVVAE	SIGLEC1	1436	Q9BZZ2
TVVRGQTNVGQDGRQ	VPS53	81	Q5VIR6
GVRLVVGVGRLAEQR	SMUG1	206	Q53HV7
GRQGSRGTAVVKVLE	TRIM23	16	P36406
VVSVQGVRGGSVELA	VSIG10L2	41	P0DP72
RRALGEIQNVGEGAT	TCFL5	356	Q9UL49
SVARVVGQQGRGRAG	TPP1	256	O14773
AQAQTIVLVGRAGVG	NLRP13	226	Q86W25
EVARQEGRIILTSGQ	EXD3	666	Q8N9H8