Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessskin epidermis development

FLG HRNR FLG2 GLI2 PKP3

6.29e-06166335GO:0098773
GeneOntologyBiologicalProcessestablishment of skin barrier

FLG HRNR FLG2

3.82e-0541333GO:0061436
GeneOntologyBiologicalProcessregulation of metanephric nephron tubule epithelial cell differentiation

FAT4 WWTR1

5.19e-057332GO:0072307
GeneOntologyBiologicalProcessmetanephric nephron tubule epithelial cell differentiation

FAT4 WWTR1

5.19e-057332GO:0072257
GeneOntologyBiologicalProcessepidermis development

FLG HRNR COL17A1 FLG2 GLI2 PKP3

8.01e-05461336GO:0008544
GeneOntologyBiologicalProcessregulation of nephron tubule epithelial cell differentiation

FAT4 WWTR1

1.91e-0413332GO:0072182
GeneOntologyBiologicalProcesspositive regulation of nuclear-transcribed mRNA poly(A) tail shortening

TNRC6B TNRC6A

2.23e-0414332GO:0060213
GeneOntologyBiologicalProcessnephron tubule epithelial cell differentiation

FAT4 WWTR1

2.57e-0415332GO:0072160
GeneOntologyBiologicalProcessregulation of nuclear-transcribed mRNA poly(A) tail shortening

TNRC6B TNRC6A

2.94e-0416332GO:0060211
GeneOntologyBiologicalProcessskin development

FLG HRNR FLG2 GLI2 PKP3

2.95e-04373335GO:0043588
GeneOntologyBiologicalProcessexternal encapsulating structure organization

THSD4 ZNF469 HRNR COL17A1 TNR

3.17e-04379335GO:0045229
GeneOntologyBiologicalProcessneuron development

EEF2K FAT4 ATAT1 CSMD3 TNR CAMSAP2 KIF26A GLI2 TIAM2

3.60e-041463339GO:0048666
GeneOntologyBiologicalProcessregulation of neuron projection development

EEF2K CSMD3 TNR CAMSAP2 KIF26A TIAM2

3.72e-04612336GO:0010975
GeneOntologyBiologicalProcessregulation of epithelial cell differentiation involved in kidney development

FAT4 WWTR1

4.17e-0419332GO:2000696
GeneOntologyBiologicalProcessmetanephric nephron tubule development

FAT4 WWTR1

5.11e-0421332GO:0072234
GeneOntologyBiologicalProcesscell differentiation involved in metanephros development

FAT4 WWTR1

5.62e-0422332GO:0072202
GeneOntologyBiologicalProcessmetanephric nephron epithelium development

FAT4 WWTR1

6.15e-0423332GO:0072243
GeneOntologyBiologicalProcessneuron projection development

EEF2K FAT4 CSMD3 TNR CAMSAP2 KIF26A GLI2 TIAM2

7.59e-041285338GO:0031175
GeneOntologyBiologicalProcessmetanephric tubule development

FAT4 WWTR1

7.88e-0426332GO:0072170
GeneOntologyBiologicalProcessmetanephric epithelium development

FAT4 WWTR1

9.14e-0428332GO:0072207
GeneOntologyBiologicalProcessforebrain development

FAT4 ATAT1 TNR KIF26A GLI2

1.01e-03489335GO:0030900
GeneOntologyCellularComponentkeratohyalin granule

FLG HRNR FLG2

3.58e-085333GO:0036457
GeneOntologyCellularComponentcornified envelope

FLG HRNR FLG2 PKP3

4.14e-0669334GO:0001533
GeneOntologyCellularComponentdesmosome

POF1B PKP3

8.90e-0428332GO:0030057
GeneOntologyCellularComponentcollagen-containing extracellular matrix

THSD4 FLG HRNR COL17A1 TNR

1.36e-03530335GO:0062023
DomainFilaggrin

FLG FLG2

3.03e-062332IPR003303
DomainAgo_hook

TNRC6B TNRC6A

9.07e-063332PF10427
DomainTNRC6-PABC_bdg

TNRC6B TNRC6A

9.07e-063332PF16608
DomainTNRC6_PABC-bd

TNRC6B TNRC6A

9.07e-063332IPR032226
DomainArgonaute_hook_dom

TNRC6B TNRC6A

9.07e-063332IPR019486
DomainS100_CABP

FLG HRNR FLG2

1.43e-0527333PS00303
DomainS_100

FLG HRNR FLG2

1.43e-0527333PF01023
DomainS100_Ca-bd_sub

FLG HRNR FLG2

1.60e-0528333IPR013787
DomainS100/CaBP-9k_CS

FLG HRNR FLG2

1.60e-0528333IPR001751
DomainS_100

FLG HRNR FLG2

1.60e-0528333SM01394
DomainEF_Hand_1_Ca_BS

FLG HRNR FLG2

3.59e-03175333IPR018247
DomainEF_HAND_1

FLG HRNR FLG2

5.50e-03204333PS00018
DomainUBA-like

TNRC6B TNRC6A

5.70e-0364332IPR009060
DomainRhoGEF

FGD5 TIAM2

6.41e-0368332SM00325
DomainDH_2

FGD5 TIAM2

6.78e-0370332PS50010
DomainRhoGEF

FGD5 TIAM2

6.78e-0370332PF00621
DomainDH-domain

FGD5 TIAM2

6.97e-0371332IPR000219
Domain-

FGD5 TIAM2

6.97e-03713321.20.900.10
DomainPH

FGD5 PLEKHA6 TIAM2

7.57e-03229333PF00169
DomainRRM

TNRC6B RBMXL3 TNRC6A

7.66e-03230333PS50102
DomainEF_HAND_2

FLG HRNR FLG2

7.75e-03231333PS50222
Domain-

FGD5 ZNRF3 TRIM9 BAZ2B

7.77e-034493343.30.40.10
DomainEF_hand_dom

FLG HRNR FLG2

7.84e-03232333IPR002048
DomainZnf_RING/FYVE/PHD

FGD5 ZNRF3 TRIM9 BAZ2B

8.38e-03459334IPR013083
Domain-

TNRC6B RBMXL3 TNRC6A

9.00e-032443333.30.70.330
DomainNucleotide-bd_a/b_plait

TNRC6B RBMXL3 TNRC6A

1.05e-02258333IPR012677
Domain-

FLG HRNR FLG2

1.08e-022613331.10.238.10
DomainPH

FGD5 PLEKHA6 TIAM2

1.28e-02278333SM00233
DomainPH_DOMAIN

FGD5 PLEKHA6 TIAM2

1.29e-02279333PS50003
DomainPH_domain

FGD5 PLEKHA6 TIAM2

1.31e-02280333IPR001849
DomainEF-hand-dom_pair

FLG HRNR FLG2

1.39e-02287333IPR011992
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

TNRC6B TNRC6A

4.88e-056262MM15083
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

TNRC6B TNRC6A

6.83e-057262M46421
PathwayREACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION

TNRC6B TNRC6A

1.17e-049262M27810
PathwayREACTOME_REGULATION_OF_NPAS4_MRNA_TRANSLATION

TNRC6B TNRC6A

1.17e-049262M46436
PathwayREACTOME_REGULATION_OF_CDH11_MRNA_TRANSLATION_BY_MICRORNAS

TNRC6B TNRC6A

1.46e-0410262M48013
PathwayREACTOME_REGULATION_OF_NPAS4_GENE_EXPRESSION

TNRC6B TNRC6A

2.52e-0413262M46434
PathwayREACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY

TNRC6B TNRC6A

4.37e-0417262M27788
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_APOPTOSIS

TNRC6B TNRC6A

5.49e-0419262M48238
PathwayREACTOME_TGFBR3_EXPRESSION

TNRC6B TNRC6A

1.20e-0328262M48253
PathwayREACTOME_CELL_JUNCTION_ORGANIZATION

TNRC6B COL17A1 TNRC6A

1.26e-03117263M19248
PathwayREACTOME_RUNX2_REGULATES_BONE_DEVELOPMENT

WWTR1 GLI2

1.47e-0331262M27805
PathwayREACTOME_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION

TNRC6B TNRC6A

1.57e-0332262M48012
PathwayREACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY

TNRC6B TNRC6A

1.57e-0332262M27900
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_NPAS4

TNRC6B TNRC6A

1.77e-0334262M46422
PathwayREACTOME_ONCOGENE_INDUCED_SENESCENCE

TNRC6B TNRC6A

1.87e-0335262M27190
PathwayREACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX

TNRC6B TNRC6A

2.09e-0337262M29790
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_VENTX

TNRC6B TNRC6A

2.57e-0341262M29748
PathwayREACTOME_CELL_CELL_COMMUNICATION

TNRC6B COL17A1 TNRC6A

2.82e-03155263M522
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

TNRC6B WWTR1 TNRC6A

3.13e-03161263M27871
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

TNRC6B TNRC6A

3.36e-0347262M29777
PathwayREACTOME_GENE_SILENCING_BY_RNA

TNRC6B TNRC6A

3.65e-0349262MM14837
PathwayREACTOME_SIGNALING_BY_TGFBR3

TNRC6B TNRC6A

3.65e-0349262M48250
Pubmed

Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin.

FLG HRNR FLG2

7.78e-10333323403047
Pubmed

Human transcription factor protein interaction networks.

TNRC6B FLG ZNF318 HRNR FLG2 SRRM2 TRIM9 GLI2 ZNF687 TNRC6A

5.18e-071429331035140242
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

TNRC6B ZNF318 HRNR CAMSAP2 TNRC6A

8.26e-0718433532908313
Pubmed

Role of GW182 protein in the cell.

TNRC6B TNRC6A

8.73e-07233229791863
Pubmed

Atopic Dermatitis Susceptibility Variants in Filaggrin Hitchhike Hornerin Selective Sweep.

FLG HRNR

8.73e-07233227678121
Pubmed

Expression of filaggrin-2 protein in the epidermis of human skin diseases: a comparative analysis with filaggrin.

FLG FLG2

8.73e-07233224813994
Pubmed

Variation in genes of the epidermal differentiation complex in German atopic dermatitis patients.

FLG HRNR FLG2

1.02e-062133319601998
Pubmed

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.

TNRC6B EEF2K WWTR1 TRIM9 TNRC6A

2.27e-0622633525900982
Pubmed

GATA3 regulates FLG and FLG2 expression in human primary keratinocytes.

FLG FLG2

2.62e-06333228928464
Pubmed

Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing.

TNRC6B TNRC6A

2.62e-06333234108231
Pubmed

Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.

TNRC6B TNRC6A

2.62e-06333216880270
Pubmed

Filaggrin and filaggrin 2 processing are linked together through skin aspartic acid protease activation.

FLG FLG2

2.62e-06333232437351
Pubmed

Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes.

TNRC6B TNRC6A

2.62e-06333231670606
Pubmed

DDX24 promotes metastasis by regulating RPL5 in non-small cell lung cancer.

FLG HRNR FLG2 POF1B PKP3

2.92e-0623833535864588
Pubmed

Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing.

TNRC6B TNRC6A

5.23e-06433221063388
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

JCAD FLG FAT4 FGD5 HRNR TIAM2 ZNF687

5.72e-0675433735906200
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

TNRC6B EEF2K FAT4 ZNF318 HRNR FLG2 TNRC6A

6.96e-0677733735844135
Pubmed

Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly.

FAT4 WWTR1

8.72e-06533230862798
Pubmed

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.

FLG HRNR FLG2 ATAT1 SRRM2 POF1B

1.27e-0555833627591049
Pubmed

Expression of Cornified Envelope Proteins in Skin and Its Relationship with Atopic Dermatitis Phenotype.

FLG FLG2

1.31e-05633227304082
Pubmed

The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.

TNRC6B TNRC6A

1.83e-05733219383768
Pubmed

Functional dissection of the human TNRC6 (GW182-related) family of proteins.

TNRC6B TNRC6A

1.83e-05733219470757
Pubmed

SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.

TNRC6B HRNR SRRM2 POF1B PKP3

1.97e-0535333527545878
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

FLG HRNR FLG2 SRRM2 POF1B ZNF687

2.01e-0560533628977666
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

ZNF318 SRRM2 CAMSAP2 KIF26A PKP3

2.19e-0536133530344098
Pubmed

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.

FLG HRNR COL17A1

2.83e-056233328344315
Pubmed

A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.

HRNR FLG2 PKP3

2.83e-056233326644517
Pubmed

TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN.

FLG HRNR FLG2 POF1B TNRC6A

2.87e-0538233537249651
Pubmed

Dchs1-Fat4 regulation of osteogenic differentiation in mouse.

FAT4 WWTR1

4.78e-051133231358536
Pubmed

Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice.

TNRC6B GLI2 TNRC6A

4.82e-057433323604909
Pubmed

LncRNA SAMD12-AS1 promotes cell proliferation and inhibits apoptosis by interacting with NPM1.

FLG HRNR

5.73e-051233231406141
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TNRC6B ZNF469 ZNF318 SRRM2 ZNRF3 ZNF687 TNRC6A

7.07e-05111633731753913
Pubmed

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.

TNRC6B TNRC6A

7.89e-051433219716330
Pubmed

PRDM14 directly interacts with heat shock proteins HSP90α and glucose-regulated protein 78.

FLG HRNR

7.89e-051433229178343
Pubmed

TRIM25 and DEAD-Box RNA Helicase DDX3X Cooperate to Regulate RIG-I-Mediated Antiviral Immunity.

FLG HRNR FLG2

8.93e-059133334445801
Pubmed

GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets.

TNRC6B TNRC6A

9.10e-051533221981923
Pubmed

TRIM30 modulates Interleukin-22-regulated papillary thyroid Cancer cell migration and invasion by targeting Sox17 for K48-linked Polyubiquitination.

HRNR FLG2

1.04e-041633231823782
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

EEF2K PLEKHA6 SRRM2 PKP3 ZNF687

1.05e-0450333516964243
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

TNRC6B ZNF318 TRIM9 TNRC6A

1.10e-0426333434702444
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

JCAD BAZ2B TNRC6A

1.29e-0410333310819331
Pubmed

Fat1 interacts with Fat4 to regulate neural tube closure, neural progenitor proliferation and apical constriction during mouse brain development.

FAT4 WWTR1

1.32e-041833226209645
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KIF26A TRIM9 TIAM2 ZNF687 TNRC6A

1.33e-0452933514621295
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

JCAD WWTR1 ATAT1 SRRM2 CAMSAP2 TRIM9

1.42e-0486133636931259
Pubmed

Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.

TNRC6B TRIM9 TNRC6A

1.44e-0410733330995489
Pubmed

Suppression of DDX39B sensitizes ovarian cancer cells to DNA-damaging chemotherapeutic agents via destabilizing BRCA1 mRNA.

HRNR FLG2 POF1B

1.44e-0410733332989256
Pubmed

Fat4/Dchs1 signaling between stromal and cap mesenchyme cells influences nephrogenesis and ureteric bud branching.

FAT4 WWTR1

1.64e-042033226116666
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

JCAD PLEKHA6 COL17A1 POF1B PKP3

1.81e-0456533525468996
Pubmed

Trinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endoderm.

TNRC6B TNRC6A

1.99e-042233222187428
Pubmed

Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung.

TNRC6B TNRC6A

2.18e-042333228811219
Pubmed

p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate.

COL17A1 PKP3

2.38e-042433228604778
Pubmed

Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation.

FAT4 WWTR1

2.80e-042633223974041
Pubmed

αE-Catenin Is a Positive Regulator of Pancreatic Islet Cell Lineage Differentiation.

GLI2 PKP3

2.80e-042633228793255
Pubmed

E3 Ligase Trim21 Ubiquitylates and Stabilizes Keratin 17 to Induce STAT3 Activation in Psoriasis.

HRNR FLG2 POF1B

2.87e-0413533329859926
Pubmed

In Vitro Identification of Histatin 5 Salivary Complexes.

FLG HRNR

3.02e-042733226544073
Pubmed

hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling.

FLG HRNR FLG2 POF1B

3.14e-0434633425324306
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

TNRC6B HRNR FLG2 POF1B DNAJB14

3.38e-0464733526618866
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

TNRC6B SRRM2 POF1B PKP3 TNRC6A

3.58e-0465533535819319
Pubmed

Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor.

FLG2 PKP3

3.74e-043033234905516
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

TNRC6B FLG HRNR FLG2 SRRM2 CLK1

4.82e-04108233638697112
Pubmed

Aerobic glycolysis tunes YAP/TAZ transcriptional activity.

WWTR1 HRNR FLG2

4.88e-0416233325796446
Pubmed

DNA Damage Regulates Translation through β-TRCP Targeting of CReP.

WWTR1 TRIM9

5.09e-043533226091241
Pubmed

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.

TNRC6B HRNR TNRC6A

5.24e-0416633335687106
Pubmed

Thioredoxin interacting protein (Txnip) forms redox sensitive high molecular weight nucleoprotein complexes.

FLG HRNR

5.39e-043633231669268
Pubmed

Endogenous human MDM2-C is highly expressed in human cancers and functions as a p53-independent growth activator.

ZNF318 HRNR

5.39e-043633224147044
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TNRC6B SRRM2 CSMD3 CAMSAP2

5.78e-0440733412693553
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FAT4 HRNR TNR TRIM9 BAZ2B

6.08e-0473633529676528
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TNRC6B ZNF318 ZNF687 TNRC6A

6.39e-0441833434709266
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

WWTR1 PKP3 TNRC6A

6.64e-0418033335198878
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

JCAD ZNF469 HRNR GLI2

7.10e-0443033435044719
Pubmed

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

EEF2K HRNR FLG2 ZNF687

7.22e-0443233423455922
Pubmed

A GO catalogue of human DNA-binding transcription factors.

ZNF469 ZNF687

7.34e-044233234673265
Pubmed

Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons.

KIF26A BAZ2B

7.34e-044233224997765
Pubmed

Extracellular Hsp90α and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1.

HRNR FLG2

8.06e-044433231273033
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

TNRC6B WWTR1 PKP3 TNRC6A

8.90e-0445733432344865
InteractionBTRC interactions

TNRC6B EEF2K WWTR1 HRNR FLG2 ZNRF3 TRIM9 GLI2 TNRC6A

2.95e-06775339int:BTRC
InteractionGLI3 interactions

THSD4 TNRC6B GLI2 TNRC6A

1.93e-0598334int:GLI3
InteractionPI4KAP1 interactions

FLG FLG2 POF1B

2.53e-0535333int:PI4KAP1
InteractionDDX24 interactions

FLG HRNR FLG2 CSMD3 POF1B PKP3 ZNF687

4.18e-05596337int:DDX24
InteractionPRSS16 interactions

FLG FLG2 POF1B

5.06e-0544333int:PRSS16
InteractionCYLD interactions

TNRC6B FLG HRNR FLG2 ATAT1 SRRM2 POF1B TNRC6A

6.09e-05868338int:CYLD
InteractionTJP2 interactions

JCAD FGD5 SRRM2 CLK1 TNRC6A

9.84e-05288335int:TJP2
InteractionCFAP210 interactions

TRIM9 PKP3

1.16e-0410332int:CFAP210
InteractionCNOT1 interactions

TNRC6B EEF2K WWTR1 GLI2 TNRC6A

1.29e-04305335int:CNOT1
InteractionAMOT interactions

JCAD TNRC6B WWTR1 CAMSAP2 TNRC6A

1.43e-04312335int:AMOT
InteractionCEP85 interactions

TNRC6B WWTR1 GLI2 TNRC6A

1.62e-04169334int:CEP85
InteractionSAMD12 interactions

FLG HRNR

2.01e-0413332int:SAMD12
InteractionDSG1 interactions

FLG HRNR FLG2 PKP3

2.24e-04184334int:DSG1
InteractionGPR18 interactions

FLG POF1B

2.34e-0414332int:GPR18
InteractionGPBP1 interactions

TNRC6B PKP3 TNRC6A

2.49e-0475333int:GPBP1
InteractionSH2D3A interactions

FLG FLG2 POF1B

2.49e-0475333int:SH2D3A
InteractionKLF5 interactions

FLG WWTR1 HRNR FLG2

2.79e-04195334int:KLF5
InteractionARL16 interactions

TNRC6B ZNF318 TNRC6A

3.36e-0483333int:ARL16
InteractionTLE3 interactions

ZNF318 SRRM2 BAZ2B GLI2 TNRC6A

3.40e-04376335int:TLE3
InteractionPTDSS1 interactions

FLG FLG2 POF1B PKP3

3.83e-04212334int:PTDSS1
InteractionDPRX interactions

HRNR FLG2

3.91e-0418332int:DPRX
InteractionGTSE1 interactions

TNRC6B CAMSAP2 PKP3 TNRC6A

4.04e-04215334int:GTSE1
InteractionCFTR interactions

TNRC6B FLG FGD5 PLEKHA6 HRNR FLG2 POF1B DNAJB14 TIAM2

4.65e-041480339int:CFTR
InteractionRNF31 interactions

HRNR SRRM2 POF1B PKP3 TNRC6A

4.67e-04403335int:RNF31
InteractionNUP43 interactions

TNRC6B ZNF318 SRRM2 CSMD3 BAZ2B ZNF687

4.71e-04625336int:NUP43
InteractionMPHOSPH9 interactions

TNRC6B CAMSAP2 TNRC6A

5.00e-0495333int:MPHOSPH9
InteractionCNOT9 interactions

TNRC6B ZNF318 GLI2 TNRC6A

5.30e-04231334int:CNOT9
InteractionFCF1 interactions

FLG POF1B PKP3

5.47e-0498333int:FCF1
InteractionKRT18 interactions

FLG FGD5 COL17A1 PKP3 TNRC6A

5.57e-04419335int:KRT18
InteractionANXA2 interactions

FLG WWTR1 FGD5 FLG2 RSC1A1

5.57e-04419335int:ANXA2
InteractionDSP interactions

TNRC6B HRNR COL17A1 FLG2 PKP3

5.82e-04423335int:DSP
InteractionRNF43 interactions

TNRC6B ZNF318 ZNRF3 TRIM9 TNRC6A

6.07e-04427335int:RNF43
InteractionST6GALNAC6 interactions

FLG POF1B PKP3

6.51e-04104333int:ST6GALNAC6
InteractionCDC16 interactions

WWTR1 ZNF318 ZNF687 TNRC6A

6.71e-04246334int:CDC16
InteractionLATS1 interactions

JCAD TNRC6B WWTR1 SRRM2 TNRC6A

6.95e-04440335int:LATS1
InteractionKRT8 interactions

TNRC6B FGD5 CAMSAP2 CLK1 TNRC6A

7.02e-04441335int:KRT8
InteractionKRT17 interactions

FGD5 HRNR FLG2 POF1B

7.34e-04252334int:KRT17
Cytoband1q21.3

FLG HRNR FLG2 ZNF687

1.55e-061173341q21.3
CytobandEnsembl 112 genes in cytogenetic band chr1q21

FLG HRNR FLG2 ZNF687

1.98e-04404334chr1q21
Cytoband1q32.1

PLEKHA6 CAMSAP2

2.76e-031083321q32.1
CytobandEnsembl 112 genes in cytogenetic band chr16p12

EEF2K TNRC6A

6.83e-03172332chr16p12
GeneFamilyEF-hand domain containing|S100 fused type protein family

FLG HRNR FLG2

7.17e-0872431350
GeneFamilyAtaxins|Trinucleotide repeat containing

TNRC6B TNRC6A

4.97e-0425242775
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

FGD5 PLEKHA6 TIAM2

2.47e-03206243682
GeneFamilyEF-hand domain containing

FLG HRNR FLG2

2.94e-03219243863
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

FGD5 TIAM2

3.44e-0366242722
GeneFamilyFibronectin type III domain containing

TNR TRIM9

1.89e-02160242555
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K1

JCAD COL17A1 KIF26A PKP3

7.37e-05150324facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K1
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#4_top-relative-expression-ranked_100

COL17A1 POF1B

9.83e-0510322gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_100_k4
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JCAD FAT4 WWTR1 FGD5 BAZ2B

2.97e-07193335aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JCAD FAT4 WWTR1 FGD5 BAZ2B

2.97e-07193335c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 JCAD FAT4 WWTR1 FGD5

3.29e-07197335c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 JCAD FAT4 WWTR1 FGD5

3.29e-071973352844dbcd0a673ed81c99920aa45858651a00736d
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD FAT4 FGD5 COL17A1

8.67e-061773348ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF318 SRRM2 BAZ2B CLK1

9.67e-06182334eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF318 SRRM2 BAZ2B CLK1

9.88e-0618333428cbf909424f3be4491d49832f0aca0386560814
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THSD4 JCAD FGD5 POF1B

9.88e-06183334c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF318 SRRM2 BAZ2B CLK1

9.88e-061833343fa608aa6b119869ec3280dc388dfee57160e63a
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD FAT4 FGD5 KIF26A

1.03e-05185334f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCellTCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma-6|TCGA-Skin / Sample_Type by Project: Shred V9

COL17A1 FLG2 POF1B PKP3

1.08e-051873342ca7928baf0c5e61f7294ed05e6e6f0e0adf9d3f
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL17A1 POF1B GLI2 PKP3

1.12e-051893346f0fc5271a7d3682f145e734abc3be6473dda2e2
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

THSD4 JCAD FGD5 TNR

1.12e-05189334b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL17A1 POF1B GLI2 PKP3

1.12e-051893343b9ce8964b16cb2200d30cbb0bfc711dcad2380e
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL17A1 POF1B GLI2 PKP3

1.12e-0518933438acb307907fde68b992057714448c1561d69ee3
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD WWTR1 FGD5 KIF26A

1.15e-05190334c8370c922e0cf0e0c36e02e1ed2b4053ad6a8073
ToppCellTCGA-Skin-Primary_Tumor|TCGA-Skin / Sample_Type by Project: Shred V9

COL17A1 FLG2 POF1B PKP3

1.15e-05190334e2b26a03c6ab24d9b0f4150c47597be37767d86e
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD WWTR1 FGD5 KIF26A

1.15e-051903345174f91a880f85bb20806023aa68bd4b8ca24ea5
ToppCellTCGA-Skin-Primary_Tumor-Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

COL17A1 FLG2 POF1B PKP3

1.15e-0519033401fb45add4661bc86cd0a34fac35177907152dbb
ToppCellTCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

COL17A1 FLG2 POF1B PKP3

1.15e-051903343188c7bd225cbcf46a21e2fb784336cdd9665995
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

THSD4 JCAD FAT4 FGD5

1.15e-051903340e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD WWTR1 FGD5 KIF26A

1.15e-0519033490e494cbfbed33a3a0d29bb7dae83f0c81580bcf
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

THSD4 JCAD FAT4 FGD5

1.17e-05191334f229abf69a1217194f74b0502486907e07dba989
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD FAT4 FGD5 KIF26A

1.17e-05191334b9ae5af426e7a1f2652a47700bb168371bd2dec6
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JCAD FAT4 WWTR1 FGD5

1.19e-05192334c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 WWTR1 FGD5 KIF26A

1.19e-05192334bcd8876235be503186f119653b39476488c0fa15
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 WWTR1 FGD5 KIF26A

1.19e-05192334f4cd65e6c5b17bcabf45fe5b687246c72e7975f7
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

TNRC6B SRRM2 ZNRF3 TNRC6A

1.19e-05192334916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JCAD FAT4 WWTR1 FGD5

1.19e-0519233404f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD FAT4 WWTR1 FGD5

1.22e-05193334826b8dd801298b3e0cd76232feae5a14026b8806
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JCAD FAT4 WWTR1 FGD5

1.22e-05193334e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JCAD FAT4 WWTR1 FGD5

1.22e-0519333402f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JCAD FAT4 WWTR1 FGD5

1.22e-051933346e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

TNRC6B SRRM2 ZNRF3 TNRC6A

1.22e-05193334e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD FAT4 WWTR1 FGD5

1.22e-0519333487d3a577d37fb0cb4b6313c596310de452bc3872
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 WWTR1 FGD5 BAZ2B

1.22e-05193334e1d546165dcc2392f540162206852c4717d7306f
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JCAD FAT4 WWTR1 FGD5

1.22e-051933345122b1ffba42de190061be34ecdc6176f84e56a3
ToppCellCOVID-19-Endothelial_cells-Inflamed_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

THSD4 JCAD WWTR1 FGD5

1.22e-05193334979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD FAT4 FGD5 KIF26A

1.22e-05193334d485634c564b268e344b6a2863c26f6adaec9e38
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 WWTR1 FGD5 BAZ2B

1.24e-051943340b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JCAD FAT4 WWTR1 FGD5

1.24e-051943341d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JCAD FAT4 WWTR1 FGD5

1.24e-0519433443f92b0533e26633dc94cce554045d641ef8fd76
ToppCellASK454-Endothelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

JCAD FAT4 WWTR1 FGD5

1.29e-0519633414dd6956ef420b660be0baf52a66960e57d75d16
ToppCellASK454-Endothelial-Endothelium|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

JCAD FAT4 WWTR1 FGD5

1.29e-051963342b777a2026b56839112fd179f2db482c49f4594a
ToppCellCOVID-19-lung-Capillary_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

JCAD FAT4 WWTR1 FGD5

1.29e-05196334ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 JCAD FAT4 FGD5

1.29e-05196334e224338490691d92c1f70b57112fabdcc92b06a9
ToppCellCOVID-19-lung-Capillary_1|lung / Disease (COVID-19 only), tissue and cell type

JCAD FAT4 WWTR1 FGD5

1.32e-051973347e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCellSkin|World / Skin and Kidney Cells in Lupus Nephritis Patients.

FLG EEF2K COL17A1 PKP3

1.37e-051993346be1340413ee868c610b6e3f58c65b493eb22bb5
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 TNRC6B BAZ2B TNRC6A

1.37e-0519933494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell3'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD FAT4 WWTR1 FGD5

1.37e-051993340075bcc7d2a5031e76a24cb176e16ac998d846fd
ToppCellKidney-Keratinocytes|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.

EEF2K COL17A1 POF1B PKP3

1.40e-0520033441d83faa9f45ee7ea2ab19be8ecc6d2c5ac7fe5d
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-6|TCGA-Bladder / Sample_Type by Project: Shred V9

THSD4 FLG FLG2

1.13e-04127333d61b71572eab8a850ee8ce54323fb247525006e5
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNR KIF26A TRIM9

1.41e-04137333b831d917f5073ccff158662adb281d34f023126a
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNR KIF26A TRIM9

1.41e-04137333cf3e928d9a7a7349840bb87475a42a07f65b94f0
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNR KIF26A TRIM9

1.41e-041373335d82d6c7eef4ec7a7fae60e37fb956488314987e
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Krt80|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WWTR1 KIF26A TIAM2

1.53e-0414133340ef6d792e11fe10963d64eb0b606b90556c1a70
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma|TCGA-Brain / Sample_Type by Project: Shred V9

CSMD3 TNR CAMSAP2

2.27e-041613335f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3_VIP_CBLN1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

THSD4 FAT4 KIF26A

2.48e-04166333688e3c01ffcec01eb7027df6f3bde8fecfb50479
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

THSD4 JCAD FGD5

2.52e-041673335af9127bae05768a5164d5708a4ad37edca99324
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D231|Adult / Lineage, Cell type, age group and donor

FAT4 FGD5 KIF26A

2.57e-04168333aca34c51758c65925ad24110294a72b2dea6db72
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

THSD4 WWTR1 CAMSAP2

2.57e-04168333c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D122|Adult / Lineage, Cell type, age group and donor

JCAD FGD5 KIF26A

2.57e-041683338c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD FAT4 FGD5

2.66e-0417033350c6c571591aa4b218caefe5778c570c809f567e
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD FAT4 FGD5

2.66e-041703338fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD FAT4 FGD5

2.66e-041703333232db50b1a40f861e981a1b9c9073b81af9f832
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 FAT4 GLI2

2.71e-04171333972fab891135bd755d5526cbc5a963200067b0a6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 FAT4 GLI2

2.71e-041713332a77ed79c6f2e700e789c80451a70ecb31639719
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HRNR TRIM9 GLI2

2.75e-041723331ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HRNR TRIM9 GLI2

2.75e-04172333ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL17A1 POF1B PKP3

2.80e-041733331b2508cc890430bd4b2cf232c633928edb86c57e
ToppCellwk_15-18-Mesenchymal-Fibroblast-Mesenchymal_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

THSD4 ZNF318 TIAM2

2.80e-04173333b43817a6b1ed8d6b5366702343be4311c0d52d83
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D231|Adult / Lineage, Cell type, age group and donor

FAT4 WWTR1 FGD5

2.85e-041743332dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGD5 KIF26A TIAM2

2.95e-0417633327e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 FAT4 GLI2

2.95e-041763339bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 FAT4 GLI2

2.95e-041763333f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

JCAD FGD5 KIF26A

2.99e-041773335ff8dcfb030312126695d53a026d2e104a401b83
ToppCelltumor_Lung-Endothelial_cells-EPCs|tumor_Lung / Location, Cell class and cell subclass

JCAD ZNF318 KIF26A

2.99e-04177333f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

TNRC6B CSMD3 TNR

2.99e-04177333e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)|367C / Donor, Lineage, Cell class and subclass (all cells)

JCAD WWTR1 FGD5

3.04e-04178333e1e96a0e3ff718ebf676a982bc63e8ced6984059
ToppCellwk_20-22-Epithelial-Proximal_epithelial-basal_late|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

COL17A1 POF1B PKP3

3.04e-0417833303f22485074b3cbf9a6ad4d543c5bbfa826dc741
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)-|367C / Donor, Lineage, Cell class and subclass (all cells)

JCAD WWTR1 FGD5

3.04e-04178333363e8b23b3834692a8a79e5fdc7b43bd3a4dab5e
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1|TCGA-Adrenal / Sample_Type by Project: Shred V9

PLEKHA6 TNR KIF26A

3.09e-04179333431e1b29015ec817f778499106d24b19cfc825ae
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 GLI2 TIAM2

3.09e-0417933302c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell10x3'2.3-week_12-13-Myeloid_macrophage-stroma-erythroid_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

THSD4 JCAD ZNF469

3.09e-04179333c17ae394b855f01f8ca1765c416fd8b34a96e60b
ToppCellCOVID-19-kidney-PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

JCAD WWTR1 FGD5

3.15e-04180333493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

JCAD FGD5 TNR

3.15e-04180333b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL17A1 POF1B PKP3

3.20e-04181333a5e770b5b5d57cbac18560828e89f7c96b687743
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

THSD4 JCAD FGD5

3.20e-04181333c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHA6 ATAT1 TNR

3.20e-041813334e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHA6 ATAT1 TNR

3.20e-04181333ad30c01290fb98adbd0caed301a584761212c977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHA6 ATAT1 TNR

3.20e-041813333a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD FAT4 COL17A1

3.20e-041813334df7972f88117108698efd06b124b232f8588981
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL17A1 POF1B PKP3

3.20e-041813336b43dcaeeb02ad5900772b6f16f1581847050e38
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAT4 FGD5 KIF26A

3.20e-041813334d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL17A1 POF1B PKP3

3.20e-04181333504b1af1951a7a20ef5db69d84c20630ec64095b
ToppCellPND07-Epithelial-Epithelial_Airway-Basal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL17A1 POF1B PKP3

3.20e-04181333f50561fdacfb83ba85fe6476e7cbc2bad1ebc826
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD FAT4 COL17A1

3.20e-04181333cbb530566893281289026bfd93adf721decd4ca3
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL17A1 POF1B PKP3

3.20e-04181333a55ec36d2393f7a376feb42b22aee75dfdf4c383
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

THSD4 JCAD FGD5

3.25e-04182333a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 TRIM9 GLI2

3.25e-0418233344764676ed3f51ba171ce63f669390392fa50a43
DrugSTOCK1N-35215; Down 200; 10uM; PC3; HT_HG-U133A

JCAD TNRC6B WWTR1 COL17A1 TRIM9 PKP3

3.14e-071933366427_DN
DrugF0447-0125; Down 200; 10uM; PC3; HT_HG-U133A

WWTR1 COL17A1 TRIM9 GLI2 PKP3

6.45e-061843356429_DN
Diseaseaortic measurement

THSD4 JCAD TNRC6B FGD5

1.52e-04251324EFO_0020865
DiseaseAntihypertensive use measurement

FGD5 ZNF318 ZNRF3 TNRC6A

1.88e-04265324EFO_0009927
DiseaseDrug Use Disorders

THSD4 CSMD3 TIAM2

2.63e-04115323C0013222
DiseaseDrug Dependence

THSD4 CSMD3 TIAM2

2.63e-04115323C1510472
DiseaseDrug habituation

THSD4 CSMD3 TIAM2

2.63e-04115323C0013170
DiseaseSubstance Dependence

THSD4 CSMD3 TIAM2

2.63e-04115323C0038580
DiseaseSubstance Use Disorders

THSD4 CSMD3 TIAM2

2.63e-04115323C0038586
DiseaseSubstance-Related Disorders

THSD4 CSMD3 TIAM2

2.63e-04115323C0236969
DiseaseDrug abuse

THSD4 CSMD3 TIAM2

2.63e-04115323C0013146
DiseaseOrganic Mental Disorders, Substance-Induced

THSD4 CSMD3 TIAM2

2.63e-04115323C0029231
DiseasePrescription Drug Abuse

THSD4 CSMD3 TIAM2

2.63e-04115323C4316881
DiseaseSubstance abuse problem

THSD4 CSMD3 TIAM2

2.70e-04116323C0740858
Diseaseascending aortic diameter

THSD4 TNRC6B FGD5

4.69e-04140323EFO_0021787
Diseaseneurodegenerative disease (implicated_via_orthology)

FAT4 WWTR1 ATAT1

5.19e-04145323DOID:1289 (implicated_via_orthology)
Diseaseglucose metabolism measurement, age-related hearing impairment

ZNF469 TRIM9

1.46e-0352322EFO_0005782, EFO_0009367
Diseasealcohol use disorder measurement

JCAD CSMD3 TNRC6A

1.60e-03214323EFO_0009458
Diseasewaist-hip ratio

THSD4 JCAD TNRC6B ZNF318 ZNRF3 TNRC6A

1.82e-031226326EFO_0004343
Diseasepolycystic ovary syndrome

WWTR1 ZNRF3

1.94e-0360322EFO_0000660
Diseasemean arterial pressure

FGD5 ZNF318 ZNRF3 TNRC6A

2.00e-03499324EFO_0006340
Diseasecarcinoma (implicated_via_orthology)

FAT4 WWTR1

2.20e-0364322DOID:305 (implicated_via_orthology)
Diseasepulse pressure measurement, alcohol drinking

JCAD ZNF318

2.63e-0370322EFO_0004329, EFO_0005763
Diseaseaxial length measurement

ZNF469 ZNRF3

3.17e-0377322EFO_0005318

Protein segments in the cluster

PeptideGeneStartEntry
RHAYEGSSSGNSSPE

COL17A1

106

Q9UMD9
RGFSAPYQGSSTLTH

CSMD3

336

Q7Z407
SFHSRTSGKSNRNGP

BAZ2B

151

Q9UIF8
GPNSELHYSLSGRNS

FAT4

2496

Q6V0I7
PSYGQGLRTSSLSHS

FAT4

4676

Q6V0I7
QSAPSTGGRQGSHYD

FLG

2106

P20930
QDSAYHSGIQSRGSP

FLG

3936

P20930
RYQNHSSKSSGRSGR

CLK1

96

P49759
SRSRQSSYGQHGSGS

FLG2

536

Q5D862
PSYSSHQQSRGGADS

JCAD

296

Q9P266
SSGSFSQRNHLPSSG

FGD5

591

Q6ZNL6
RQGSSAGSSSSYGQH

HRNR

506

Q86YZ3
GRHESGSRQSSSYGP

HRNR

546

Q86YZ3
GRSSSRGPYESRSGH

HRNR

1266

Q86YZ3
SSRYGQHGSGSRQSS

HRNR

1686

Q86YZ3
GRSSSRGPYESRSGH

HRNR

1736

Q86YZ3
SSRYGQHGSGSRQSS

HRNR

2156

Q86YZ3
GRSSSRGPYESRSGH

HRNR

2206

Q86YZ3
RPQRYSSGHGSDNSS

KIF26A

1621

Q9ULI4
LGAGRPHNASSADSY

GLI2

841

P10070
IYSSHNQPSTGGRTT

POF1B

531

Q8WVV4
PSGSVHSFSNGRAGY

DNAJB14

211

Q8TBM8
YSRHGGVNSSSPNTG

ATAT1

336

Q5SQI0
NHRESENSGDSGYPS

EEF2K

431

O00418
TSDGFNHPARSSGQS

RSC1A1

6

Q92681
SRYSRPQAHSSASGG

CAMSAP2

396

Q08AD1
GGSGYHSRSPARQES

SRRM2

1816

Q9UQ35
NSYGSHRTLQRLSSG

PKP3

301

Q9Y446
HRGGLGPSATYSSNS

PLEKHA6

676

Q9Y2H5
SRGVAYSTHRTNAPG

TIAM2

86

Q8IVF5
SGGRNSSSNSYGQSH

RBMXL3

401

Q8N7X1
GGRSPDTYSRGHDSS

RBMXL3

721

Q8N7X1
PNAYSGGHNSSSRND

RBMXL3

796

Q8N7X1
GDHDRSSNSYGRSDR

RBMXL3

996

Q8N7X1
NGTAGDSLSYHQGRP

TNR

1261

Q92752
RGHSSYSPSNTARLG

ZNF469

2296

Q96JG9
SPQSHRAAGSGVSDY

TRIM9

46

Q9C026
NYSSNSSLEHRGPNS

ZNRF3

666

Q9ULT6
SGGHGPLRYRSSSST

ZNF687

1106

Q8N1G0
SQGASSARHGYSSPA

THSD4

201

Q6ZMP0
GGDHPSFTSGTRNYR

ZNF318

286

Q5VUA4
STSGSHYENSQRGPV

TNRC6A

201

Q8NDV7
GSSDSHNSGRRSYRP

TNRC6B

581

Q9UPQ9
NGGPYHSREQSTDSG

WWTR1

301

Q9GZV5